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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Ezh2_Atf2_Ikzf1

Z-value: 1.77

Motif logo

Transcription factors associated with Ezh2_Atf2_Ikzf1

Gene Symbol Gene ID Gene Info
ENSRNOG00000006048 enhancer of zeste 2 polycomb repressive complex 2 subunit
ENSRNOG00000001597 activating transcription factor 2
ENSRNOG00000004444 IKAROS family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Atf2rn6_v1_chr3_-_60765645_607656450.513.7e-22Click!
Ikzf1rn6_v1_chr14_+_91783514_91783514-0.441.7e-16Click!
Ezh2rn6_v1_chr4_-_77347011_77347011-0.211.3e-04Click!

Activity profile of Ezh2_Atf2_Ikzf1 motif

Sorted Z-values of Ezh2_Atf2_Ikzf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_110046687 98.23 ENSRNOT00000057404
ENSRNOT00000006624
ENSRNOT00000089695
sodium leak channel, non-selective
chr7_+_123510804 88.84 ENSRNOT00000010491
septin 3
chr15_+_33600102 85.70 ENSRNOT00000022664
CKLF-like MARVEL transmembrane domain containing 5
chr17_-_10766253 74.98 ENSRNOT00000000117
complexin 2
chr4_+_175729726 70.82 ENSRNOT00000013230
solute carrier organic anion transporter family, member 1c1
chr3_-_44086006 69.53 ENSRNOT00000034449
ENSRNOT00000082604
ermin
chr3_+_113318563 69.08 ENSRNOT00000089230
creatine kinase, mitochondrial 1
chr7_-_136853154 67.72 ENSRNOT00000087376
neural EGFL like 2
chr7_-_136853957 66.84 ENSRNOT00000008985
neural EGFL like 2
chr11_-_35098883 66.39 ENSRNOT00000079955
potassium voltage-gated channel subfamily J member 6
chr3_+_129599353 66.03 ENSRNOT00000008734
synaptosomal-associated protein 25
chr11_+_58624198 64.74 ENSRNOT00000002091
growth associated protein 43
chr1_+_234252757 63.96 ENSRNOT00000091814
RAR-related orphan receptor B
chr10_+_42614713 62.85 ENSRNOT00000081136
ENSRNOT00000073148
glutamate ionotropic receptor AMPA type subunit 1
chrX_+_107496072 58.66 ENSRNOT00000003283
proteolipid protein 1
chr13_-_72367980 55.26 ENSRNOT00000003928
calcium voltage-gated channel subunit alpha1 E
chr1_+_25174456 54.63 ENSRNOT00000092830
clavesin 2
chr4_-_16669368 54.10 ENSRNOT00000007608
piccolo (presynaptic cytomatrix protein)
chr4_+_22859622 53.76 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr10_+_42618487 52.81 ENSRNOT00000071615
glutamate ionotropic receptor AMPA type subunit 1
chr4_-_169999873 52.53 ENSRNOT00000011697
glutamate ionotropic receptor NMDA type subunit 2B
chr15_-_77736892 52.05 ENSRNOT00000057924
protocadherin 9
chr16_-_21089508 50.15 ENSRNOT00000072565
hyaluronan and proteoglycan link protein 4
chr4_-_51844331 48.83 ENSRNOT00000003593
G protein-coupled receptor 37
chr4_-_11497531 48.69 ENSRNOT00000078799
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_+_51687809 48.03 ENSRNOT00000087242
sodium voltage-gated channel alpha subunit 2
chr6_-_147172022 46.66 ENSRNOT00000080675
integrin subunit beta 8
chr2_-_179704629 45.68 ENSRNOT00000083361
ENSRNOT00000077941
glutamate ionotropic receptor AMPA type subunit 2
chr9_+_60039297 44.53 ENSRNOT00000016262
solute carrier family 39 member 10
chr4_-_16654811 42.89 ENSRNOT00000008637
piccolo (presynaptic cytomatrix protein)
chr17_-_58292624 42.76 ENSRNOT00000047512
adenosine deaminase, RNA-specific, B2
chr7_-_44121130 42.31 ENSRNOT00000005706
neurotensin
chr2_-_187401786 41.97 ENSRNOT00000025624
hyaluronan and proteoglycan link protein 2
chr9_+_82571269 40.95 ENSRNOT00000026941
SPEG complex locus
chr14_+_8080565 40.42 ENSRNOT00000092395
mitogen activated protein kinase 10
chr9_+_82596355 39.43 ENSRNOT00000065076
SPEG complex locus
chr14_+_8080275 39.35 ENSRNOT00000065965
ENSRNOT00000092542
mitogen activated protein kinase 10
chr12_-_10307265 39.20 ENSRNOT00000092627
WAS protein family, member 3
chr7_-_125407806 38.57 ENSRNOT00000084666
similar to mKIAA1644 protein
chr10_+_65586993 37.06 ENSRNOT00000086036
aldolase, fructose-bisphosphate C
chr2_+_69415057 36.93 ENSRNOT00000013152
cadherin 10
chr18_-_18079560 36.73 ENSRNOT00000072093

chr3_+_113257688 35.45 ENSRNOT00000019320
microtubule-associated protein 1A
chr18_-_67224566 35.09 ENSRNOT00000064947
DCC netrin 1 receptor
chr7_-_50278842 34.24 ENSRNOT00000088950
synaptotagmin 1
chr3_+_35175313 34.15 ENSRNOT00000081744
kinesin family member 5C
chr3_-_64554953 33.95 ENSRNOT00000067452
serine/arginine repetitive matrix protein 1-like
chr2_-_35104963 33.93 ENSRNOT00000018058
regulator of G-protein signaling 7-binding protein
chr6_-_114488880 33.88 ENSRNOT00000087560

chr18_+_30562178 33.79 ENSRNOT00000040998
protocadherin beta-16-like
chrX_-_116792864 33.63 ENSRNOT00000090918
angiomotin
chrX_-_29648359 33.39 ENSRNOT00000086721
ENSRNOT00000006777
glycoprotein m6b
chrX_-_116792707 32.67 ENSRNOT00000049482
angiomotin
chr11_+_36851038 32.44 ENSRNOT00000002221
ENSRNOT00000061047
Purkinje cell protein 4
chrX_+_107323215 32.40 ENSRNOT00000071874
transcription elongation factor A like 3
chrX_-_152642531 32.35 ENSRNOT00000085037
gamma-aminobutyric acid type A receptor alpha3 subunit
chr11_+_45888221 31.86 ENSRNOT00000071932
ENSRNOT00000066008
ENSRNOT00000060802
leukemia NUP98 fusion partner 1
chr3_-_52664209 31.84 ENSRNOT00000065126
ENSRNOT00000079020
sodium voltage-gated channel alpha subunit 9
chr1_-_5165859 31.75 ENSRNOT00000044325
ENSRNOT00000019319
glutamate metabotropic receptor 1
chr6_+_64789940 31.49 ENSRNOT00000085979
ENSRNOT00000059739
ENSRNOT00000051908
ENSRNOT00000082793
ENSRNOT00000078583
ENSRNOT00000091677
ENSRNOT00000093241
neuronal cell adhesion molecule
chr10_-_15928169 31.08 ENSRNOT00000028069
neuron specific gene family member 2
chrX_-_142248369 31.04 ENSRNOT00000091330
fibroblast growth factor 13
chr9_-_71852113 30.85 ENSRNOT00000083263
ENSRNOT00000072983

chr14_+_109533792 29.90 ENSRNOT00000067690
ankyrin repeat domain-containing protein 29-like
chr1_-_225035687 29.75 ENSRNOT00000026539
G protein subunit gamma 3
chr10_-_56211891 29.66 ENSRNOT00000015076
ATPase Na+/K+ transporting subunit beta 2
chr13_-_88061108 29.07 ENSRNOT00000003774
regulator of G-protein signaling 4
chr9_+_73433252 29.07 ENSRNOT00000092540
microtubule-associated protein 2
chr5_-_79570073 28.40 ENSRNOT00000011845
tumor necrosis factor superfamily member 15
chr7_-_50638798 28.39 ENSRNOT00000048880
synaptotagmin 1
chr9_+_73418607 28.34 ENSRNOT00000092547
microtubule-associated protein 2
chr12_+_21767606 28.29 ENSRNOT00000059602
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1-like
chr10_-_27179254 28.21 ENSRNOT00000004619
gamma-aminobutyric acid type A receptor gamma 2 subunit
chr3_-_168018410 28.09 ENSRNOT00000087579
breast carcinoma amplified sequence 1
chr1_+_101517714 27.87 ENSRNOT00000028423
pleckstrin homology domain containing A4
chr3_-_113312127 26.26 ENSRNOT00000065285
microfibrillar-associated protein 1A
chr14_-_39112600 25.97 ENSRNOT00000003170
gamma-aminobutyric acid type A receptor beta 1 subunit
chr15_-_44860604 25.85 ENSRNOT00000018637
neurofilament medium
chr13_+_57131395 25.77 ENSRNOT00000017884
potassium sodium-activated channel subfamily T member 2
chr3_-_176666282 25.60 ENSRNOT00000016947
eukaryotic translation elongation factor 1 alpha 2
chr7_+_6644643 25.07 ENSRNOT00000051670
olfactory receptor 962
chr17_-_72046381 24.94 ENSRNOT00000073919

chr3_-_168033457 24.36 ENSRNOT00000055111
breast carcinoma amplified sequence 1
chr5_-_147303346 24.33 ENSRNOT00000009153
hippocalcin
chr9_-_32019205 24.32 ENSRNOT00000016194
adhesion G protein-coupled receptor B3
chr9_+_118849302 24.20 ENSRNOT00000087592
DLG associated protein 1
chr17_+_60059949 24.03 ENSRNOT00000025458
membrane palmitoylated protein 7
chrX_+_20351486 23.58 ENSRNOT00000093675
ENSRNOT00000047444
WNK lysine deficient protein kinase 3
chr20_+_40769586 23.18 ENSRNOT00000001079
fatty acid binding protein 7
chr2_-_95472115 23.06 ENSRNOT00000015720
stathmin 2
chr17_+_81922329 22.69 ENSRNOT00000031542
calcium voltage-gated channel auxiliary subunit beta 2
chr10_-_82492918 22.62 ENSRNOT00000066895
transmembrane protein 92-like
chr1_+_16478127 22.26 ENSRNOT00000019076
Abelson helper integration site 1
chr3_+_51883559 22.22 ENSRNOT00000007197
cysteine and serine rich nuclear protein 3
chr18_-_5314511 22.08 ENSRNOT00000022637
ENSRNOT00000079682
zinc finger protein 521
chr13_-_72063347 21.86 ENSRNOT00000090544
ENSRNOT00000003869
calcium voltage-gated channel subunit alpha1 E
chr2_+_201289357 21.55 ENSRNOT00000067358
T-box 15
chr16_-_10296341 21.33 ENSRNOT00000083990
zinc finger protein 488
chr1_-_43638161 21.31 ENSRNOT00000024460
interaction protein for cytohesin exchange factors 1
chr4_+_108301129 21.26 ENSRNOT00000007993
leucine rich repeat transmembrane neuronal 1
chr15_-_76789298 21.21 ENSRNOT00000077853

chr13_+_46169963 20.85 ENSRNOT00000005212
thrombospondin type 1 domain containing 7B
chr19_+_6046665 20.84 ENSRNOT00000084126
cadherin 8
chr11_+_69484293 20.44 ENSRNOT00000049292
kalirin, RhoGEF kinase
chr6_+_101603319 20.31 ENSRNOT00000030470
gephyrin
chr9_-_63641400 20.25 ENSRNOT00000087684
SATB homeobox 2
chr11_-_59110562 20.18 ENSRNOT00000047907
ENSRNOT00000042024
limbic system-associated membrane protein
chrX_+_136460215 20.09 ENSRNOT00000093538
Rho GTPase activating protein 36
chr4_-_150829741 20.01 ENSRNOT00000051846
ENSRNOT00000052017
calcium voltage-gated channel subunit alpha1 C
chr18_+_30527705 20.00 ENSRNOT00000027168
protocadherin beta 14
chr20_-_31956649 19.94 ENSRNOT00000072429
hexokinase 1
chr10_-_97582188 19.64 ENSRNOT00000005076
regulator of G-protein signaling 9
chr8_-_98738446 19.61 ENSRNOT00000019860
Zic family member 1
chr5_-_130085838 19.60 ENSRNOT00000035252
ELAV like RNA binding protein 4
chr3_-_176816114 19.60 ENSRNOT00000079262
ENSRNOT00000018697
stathmin 3
chr4_+_138441332 19.37 ENSRNOT00000090847
contactin 4
chr18_+_30474947 19.11 ENSRNOT00000027188
protocadherin beta 9
chrX_+_62363953 19.07 ENSRNOT00000083362
aristaless related homeobox
chr2_+_247248407 18.89 ENSRNOT00000082287
unc-5 netrin receptor C
chr1_+_187149453 18.85 ENSRNOT00000082738
xylosyltransferase 1
chr18_-_38088457 18.75 ENSRNOT00000077814
janus kinase and microtubule interacting protein 2
chr2_-_57935334 18.46 ENSRNOT00000022319
ENSRNOT00000085599
ENSRNOT00000077790
ENSRNOT00000035821
solute carrier family 1 member 3
chr7_-_129970550 18.40 ENSRNOT00000055879
megalencephalic leukoencephalopathy with subcortical cysts 1
chr16_-_20097287 18.39 ENSRNOT00000025162
unc-13 homolog A
chr15_-_43542939 18.19 ENSRNOT00000012996
dihydropyrimidinase-like 2
chr14_-_3288017 18.15 ENSRNOT00000080452
hypothetical protein LOC689986
chr2_+_18392142 18.14 ENSRNOT00000043196
hyaluronan and proteoglycan link protein 1
chr1_+_128924966 18.03 ENSRNOT00000019267
insulin-like growth factor 1 receptor
chrX_+_6791136 17.86 ENSRNOT00000003984
norrin-like
chr8_-_96985558 17.83 ENSRNOT00000018553
similar to UPF0258 protein KIAA1024
chr5_-_168734296 17.76 ENSRNOT00000066120
calmodulin binding transcription activator 1
chr1_+_42169501 17.35 ENSRNOT00000025477
ENSRNOT00000092791
vasoactive intestinal peptide
chr2_+_36246628 17.30 ENSRNOT00000013618
5-hydroxytryptamine receptor 1A
chr15_-_88036354 17.23 ENSRNOT00000014747
endothelin receptor type B
chr1_-_13915594 17.20 ENSRNOT00000015927
ARFGEF family member 3
chr15_-_26175645 17.03 ENSRNOT00000020175
solute carrier family 35, member F4
chr16_-_6245644 16.92 ENSRNOT00000040759
calcium voltage-gated channel subunit alpha1 D
chr7_+_130431213 16.91 ENSRNOT00000055792
mitogen-activated protein kinase 8 interacting protein 2
chr3_-_122206671 16.84 ENSRNOT00000037576
prodynorphin
chr8_+_45797315 16.80 ENSRNOT00000059997

chr1_-_89559960 16.70 ENSRNOT00000092133
sodium voltage-gated channel beta subunit 1
chr16_-_36161089 16.40 ENSRNOT00000017888
stimulator of chondrogenesis 1
chr3_-_159775643 16.11 ENSRNOT00000010939
junctophilin 2
chr5_-_158439078 16.03 ENSRNOT00000025517
kelch domain containing 7A
chr4_-_155275161 15.88 ENSRNOT00000032690
ribosomal modification protein rimK-like family member B
chr6_+_58467254 15.80 ENSRNOT00000065396
ets variant 1
chr4_-_11610518 15.72 ENSRNOT00000066643
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_+_159165169 15.65 ENSRNOT00000087274
four and a half LIM domains 1
chr18_+_52215682 15.64 ENSRNOT00000037901
multiple EGF-like domains 10
chr20_+_20105047 15.58 ENSRNOT00000082181
ankyrin 3
chr2_+_102685513 15.53 ENSRNOT00000033940
basic helix-loop-helix family, member e22
chr20_+_5050327 15.41 ENSRNOT00000083353
dimethylarginine dimethylaminohydrolase 2
chr3_+_139695028 15.24 ENSRNOT00000089098
solute carrier family 24 member 3
chr14_+_36047144 15.23 ENSRNOT00000003088
ligand of numb-protein X 1
chr9_+_16862248 15.20 ENSRNOT00000080104
ENSRNOT00000024824
tau tubulin kinase 1
chr18_+_29966245 15.13 ENSRNOT00000074028
protocadherin alpha 4
chr7_+_139698148 14.88 ENSRNOT00000078579
phosphofructokinase, muscle
chrX_-_152641679 14.87 ENSRNOT00000080277
gamma-aminobutyric acid type A receptor alpha3 subunit
chr2_+_229196616 14.84 ENSRNOT00000012773
N-deacetylase and N-sulfotransferase 4
chr9_-_30844199 14.80 ENSRNOT00000017169
collagen type XIX alpha 1 chain
chr10_+_54156649 14.77 ENSRNOT00000074718
growth arrest specific 7
chr15_+_33121273 14.65 ENSRNOT00000016020
RRAD and GEM like GTPase 2
chr14_-_13058172 14.50 ENSRNOT00000002746
ENSRNOT00000071706
PR/SET domain 8
chr3_-_64543100 14.49 ENSRNOT00000025803
zinc finger protein 385B
chr4_-_155563249 14.40 ENSRNOT00000011298
solute carrier family 2 member 3
chr8_-_62987182 14.36 ENSRNOT00000070885
immunoglobulin superfamily containing leucine-rich repeat 2
chr5_+_154077944 14.36 ENSRNOT00000031512
interleukin 22 receptor subunit alpha 1
chrX_-_104932508 14.32 ENSRNOT00000075325
NADPH oxidase 1
chr1_+_211423022 14.28 ENSRNOT00000029587
dihydropyrimidinase-like 4
chr15_-_62200837 14.27 ENSRNOT00000017599
protocadherin 8
chr15_+_33600337 14.26 ENSRNOT00000075965
CKLF-like MARVEL transmembrane domain containing 5
chr10_+_77537340 14.26 ENSRNOT00000003297
transmembrane protein 100
chr18_+_30592794 14.23 ENSRNOT00000027133
protocadherin beta 22
chr6_-_88917070 14.17 ENSRNOT00000000767
MAM domain containing glycosylphosphatidylinositol anchor 2
chr2_+_262914327 14.14 ENSRNOT00000029312
neuronal growth regulator 1
chrX_-_82743753 14.09 ENSRNOT00000003512
ribosomal protein S6 kinase A6
chr8_-_53899669 14.06 ENSRNOT00000082257
neural cell adhesion molecule 1
chr15_+_58016238 14.03 ENSRNOT00000075786
potassium channel tetramerization domain containing 4
chr3_+_113319456 13.87 ENSRNOT00000051354
creatine kinase, mitochondrial 1
chrX_+_62363757 13.87 ENSRNOT00000091240
aristaless related homeobox
chr14_+_114152472 13.78 ENSRNOT00000042965
reticulon 4
chr17_-_52477575 13.78 ENSRNOT00000081290
GLI family zinc finger 3
chr8_+_7128656 13.66 ENSRNOT00000038313
progesterone receptor
chr14_+_39661968 13.49 ENSRNOT00000064779
gamma-aminobutyric acid type A receptor alpha2 subunit
chr1_+_101682172 13.44 ENSRNOT00000028540
carbonic anhydrase 11
chrX_-_15553720 13.44 ENSRNOT00000012646
GRIP1 associated protein 1
chr5_-_6083083 13.39 ENSRNOT00000072411
sulfatase 1
chr3_-_104502471 13.22 ENSRNOT00000040306
ryanodine receptor 3
chr8_+_39848448 13.20 ENSRNOT00000012248
hepatocyte cell adhesion molecule
chr15_-_34550850 13.12 ENSRNOT00000027794
ENSRNOT00000090228
cerebellin 3 precursor
chr3_+_131351587 13.03 ENSRNOT00000010835
BTB domain containing 3
chr2_-_173087648 13.03 ENSRNOT00000091079
IQ motif containing J
chr20_+_25990656 12.98 ENSRNOT00000081254
leucine rich repeat transmembrane neuronal 3
chr1_+_168489077 12.93 ENSRNOT00000021191
olfactory receptor 96
chr5_-_137584608 12.90 ENSRNOT00000051470
olfactory receptor 2A2-like
chr7_+_82338663 12.83 ENSRNOT00000006890
ER membrane protein complex subunit 2
chr1_+_42170583 12.78 ENSRNOT00000093104
vasoactive intestinal peptide
chr2_-_89498395 12.72 ENSRNOT00000068507

chr7_-_70480724 12.59 ENSRNOT00000090057
deltex E3 ubiquitin ligase 3
chr17_-_63994169 12.52 ENSRNOT00000075651
cholinergic receptor, muscarinic 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Ezh2_Atf2_Ikzf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
24.0 168.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
22.1 66.3 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
22.0 66.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
18.1 108.3 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
14.2 56.8 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
12.7 89.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
11.2 134.6 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
9.6 9.6 GO:0051643 endoplasmic reticulum localization(GO:0051643)
9.0 54.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
8.6 25.9 GO:0033693 neurofilament bundle assembly(GO:0033693)
8.5 34.2 GO:0098961 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
8.5 42.3 GO:0097332 response to antipsychotic drug(GO:0097332)
8.4 92.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
8.3 41.4 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
8.1 64.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
8.0 31.8 GO:0043179 rhythmic excitation(GO:0043179)
7.9 23.6 GO:2000688 positive regulation of rubidium ion transport(GO:2000682) positive regulation of rubidium ion transmembrane transporter activity(GO:2000688)
7.7 84.2 GO:0007258 JUN phosphorylation(GO:0007258)
7.6 22.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
7.5 60.3 GO:0090273 regulation of somatostatin secretion(GO:0090273)
7.4 29.7 GO:1903288 positive regulation of potassium ion import(GO:1903288)
7.4 51.8 GO:0099645 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
7.2 86.2 GO:0046548 retinal rod cell development(GO:0046548)
6.9 48.0 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
6.7 13.4 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
6.7 67.0 GO:0016198 axon choice point recognition(GO:0016198)
6.0 18.0 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
5.8 23.3 GO:0071896 protein localization to adherens junction(GO:0071896)
5.8 40.4 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
5.7 17.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
5.5 32.9 GO:0021759 globus pallidus development(GO:0021759)
5.5 43.9 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
5.5 16.4 GO:0097168 mesenchymal stem cell proliferation(GO:0097168)
5.4 32.7 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
5.3 10.7 GO:0060300 regulation of cytokine activity(GO:0060300)
5.0 20.0 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
5.0 29.8 GO:0071313 cellular response to caffeine(GO:0071313)
4.9 44.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
4.9 24.4 GO:0061743 motor learning(GO:0061743)
4.8 14.3 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
4.7 14.1 GO:0001928 regulation of exocyst assembly(GO:0001928)
4.6 18.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
4.6 13.7 GO:1904700 granulosa cell apoptotic process(GO:1904700) regulation of granulosa cell apoptotic process(GO:1904708)
4.5 62.6 GO:0005513 detection of calcium ion(GO:0005513)
4.5 22.3 GO:0060594 mammary gland specification(GO:0060594)
4.5 13.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
4.4 48.8 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
4.4 31.0 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
4.1 12.4 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
4.1 12.4 GO:0060447 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) bud outgrowth involved in lung branching(GO:0060447) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
4.1 32.9 GO:0061193 taste bud development(GO:0061193)
4.0 24.2 GO:0047484 regulation of response to osmotic stress(GO:0047484)
4.0 16.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
3.9 15.8 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
3.9 43.2 GO:0070327 thyroid hormone transport(GO:0070327)
3.9 54.8 GO:0071420 cellular response to histamine(GO:0071420)
3.9 58.7 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
3.9 15.6 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.8 11.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
3.7 14.9 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
3.7 11.0 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
3.5 21.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
3.5 31.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
3.5 7.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
3.4 37.2 GO:0071315 cellular response to morphine(GO:0071315)
3.3 30.1 GO:0060406 positive regulation of penile erection(GO:0060406)
3.3 19.9 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
3.1 9.4 GO:0097298 regulation of nucleus size(GO:0097298)
3.1 25.0 GO:0070842 aggresome assembly(GO:0070842)
3.1 9.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
3.1 98.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
3.1 9.2 GO:0060066 oviduct development(GO:0060066)
3.0 9.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
3.0 30.0 GO:0021540 corpus callosum morphogenesis(GO:0021540)
3.0 17.8 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
2.9 87.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
2.9 8.8 GO:0032053 ciliary basal body organization(GO:0032053)
2.9 14.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
2.7 8.2 GO:0032423 regulation of mismatch repair(GO:0032423)
2.7 16.3 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
2.7 8.0 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
2.7 74.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
2.7 8.0 GO:0021678 third ventricle development(GO:0021678)
2.5 10.1 GO:0001692 histamine metabolic process(GO:0001692)
2.5 15.0 GO:0097039 protein linear polyubiquitination(GO:0097039)
2.5 55.0 GO:0060992 response to fungicide(GO:0060992)
2.5 12.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
2.5 27.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
2.5 24.7 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
2.4 7.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
2.4 16.9 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
2.4 7.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
2.4 48.1 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
2.4 42.8 GO:0001573 ganglioside metabolic process(GO:0001573)
2.4 4.7 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
2.3 13.8 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
2.3 13.8 GO:0021553 olfactory nerve development(GO:0021553)
2.3 9.1 GO:0072092 ureteric bud invasion(GO:0072092)
2.2 6.6 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
2.2 4.3 GO:2000468 regulation of peroxidase activity(GO:2000468)
2.1 16.9 GO:0046958 nonassociative learning(GO:0046958)
2.1 38.0 GO:0031643 positive regulation of myelination(GO:0031643)
2.1 10.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
1.9 7.6 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
1.8 9.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.8 10.8 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551)
1.8 3.6 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
1.8 28.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
1.7 17.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
1.7 6.9 GO:0010157 response to chlorate(GO:0010157)
1.7 18.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
1.7 6.8 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
1.7 23.2 GO:0060134 prepulse inhibition(GO:0060134)
1.6 3.3 GO:2000017 regulation of determination of dorsal identity(GO:2000015) positive regulation of determination of dorsal identity(GO:2000017)
1.6 6.5 GO:0001880 Mullerian duct regression(GO:0001880)
1.6 3.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
1.5 1.5 GO:0050915 sensory perception of sour taste(GO:0050915)
1.5 6.1 GO:0050955 negative regulation of translational elongation(GO:0045900) thermoception(GO:0050955)
1.5 18.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
1.5 11.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.5 11.7 GO:0060484 lung-associated mesenchyme development(GO:0060484)
1.5 26.3 GO:0006020 inositol metabolic process(GO:0006020)
1.4 14.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
1.4 11.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
1.4 4.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
1.4 5.6 GO:0003166 bundle of His development(GO:0003166)
1.4 15.4 GO:0006527 arginine catabolic process(GO:0006527)
1.4 4.2 GO:0015755 fructose transport(GO:0015755)
1.4 6.9 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
1.4 1.4 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
1.3 5.3 GO:2000698 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
1.3 13.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.3 9.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
1.3 6.4 GO:0035063 nuclear speck organization(GO:0035063)
1.3 3.8 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
1.3 5.0 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.2 3.7 GO:0090247 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
1.2 29.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.2 7.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
1.2 168.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.2 2.4 GO:0045105 intermediate filament polymerization or depolymerization(GO:0045105)
1.2 4.7 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
1.2 82.0 GO:0055013 cardiac muscle cell development(GO:0055013)
1.2 3.5 GO:0042335 cuticle development(GO:0042335)
1.1 12.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
1.1 21.3 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
1.1 15.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
1.1 3.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
1.1 9.8 GO:0070257 positive regulation of mucus secretion(GO:0070257)
1.1 4.3 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
1.1 12.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.1 9.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.0 3.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
1.0 19.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
1.0 1.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
1.0 6.8 GO:0009838 abscission(GO:0009838)
1.0 20.2 GO:0035641 locomotory exploration behavior(GO:0035641)
1.0 10.6 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
1.0 2.9 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.9 2.8 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.9 7.5 GO:0051013 microtubule severing(GO:0051013)
0.9 4.6 GO:0008078 mesodermal cell migration(GO:0008078) establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.9 5.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.9 9.1 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.9 4.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.9 8.0 GO:0051255 spindle midzone assembly(GO:0051255)
0.9 4.4 GO:0050957 equilibrioception(GO:0050957)
0.9 7.0 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.9 47.4 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.8 3.4 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.8 73.5 GO:0032091 negative regulation of protein binding(GO:0032091)
0.8 2.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.8 7.5 GO:0051775 response to redox state(GO:0051775)
0.8 4.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.8 4.9 GO:1990928 response to amino acid starvation(GO:1990928)
0.8 5.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.8 4.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.8 5.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.8 14.2 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.8 29.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.8 17.3 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.8 6.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.8 3.1 GO:0009597 detection of virus(GO:0009597)
0.8 5.3 GO:0060017 parathyroid gland development(GO:0060017)
0.8 25.6 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.7 3.7 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.7 4.5 GO:0071000 response to magnetism(GO:0071000)
0.7 11.9 GO:0016048 detection of temperature stimulus(GO:0016048)
0.7 1.5 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.7 11.9 GO:0045793 positive regulation of cell size(GO:0045793)
0.7 8.0 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
0.7 4.4 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.7 9.4 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.7 3.6 GO:1904179 osteoblast fate commitment(GO:0002051) positive regulation of adipose tissue development(GO:1904179)
0.7 5.7 GO:1904424 regulation of GTP binding(GO:1904424)
0.7 3.5 GO:0044860 protein localization to plasma membrane raft(GO:0044860) protein transport into plasma membrane raft(GO:0044861)
0.7 10.5 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.7 1.4 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.7 10.3 GO:0071801 regulation of podosome assembly(GO:0071801)
0.7 2.7 GO:0051660 establishment of centrosome localization(GO:0051660)
0.7 5.3 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.7 6.6 GO:0051764 actin crosslink formation(GO:0051764)
0.7 2.6 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
0.7 3.9 GO:0042045 epithelial fluid transport(GO:0042045)
0.6 5.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.6 19.6 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.6 19.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.6 14.1 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.6 6.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.6 4.1 GO:0048664 neuron fate determination(GO:0048664)
0.6 4.0 GO:0042148 strand invasion(GO:0042148)
0.6 5.0 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.6 6.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.5 3.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.5 3.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.5 1.1 GO:0007172 signal complex assembly(GO:0007172)
0.5 2.6 GO:0060005 vestibular reflex(GO:0060005)
0.5 10.4 GO:0010107 potassium ion import(GO:0010107)
0.5 18.8 GO:0048747 muscle fiber development(GO:0048747)
0.5 13.4 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.5 45.4 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.5 19.6 GO:0042220 response to cocaine(GO:0042220)
0.5 3.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.5 4.9 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.5 1.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.5 10.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.5 1.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.5 16.8 GO:0048663 neuron fate commitment(GO:0048663)
0.5 1.4 GO:0031989 bombesin receptor signaling pathway(GO:0031989)
0.5 22.7 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.5 5.4 GO:0051382 kinetochore assembly(GO:0051382)
0.4 0.9 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.4 6.8 GO:0010669 epithelial structure maintenance(GO:0010669)
0.4 2.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.4 10.4 GO:0017004 cytochrome complex assembly(GO:0017004)
0.4 8.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.4 2.5 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.4 15.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.4 1.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.4 0.4 GO:1903525 regulation of membrane tubulation(GO:1903525)
0.4 4.9 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.4 7.4 GO:0008542 visual learning(GO:0008542)
0.4 3.7 GO:0044804 nucleophagy(GO:0044804)
0.4 2.8 GO:2000811 negative regulation of anoikis(GO:2000811)
0.3 2.7 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.3 1.0 GO:0071031 nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
0.3 1.6 GO:0022007 neural plate morphogenesis(GO:0001839) neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 5.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.3 5.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.3 2.5 GO:0016926 protein desumoylation(GO:0016926)
0.3 0.9 GO:0000958 mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962)
0.3 4.5 GO:0071625 vocalization behavior(GO:0071625)
0.3 13.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.3 1.5 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.3 0.9 GO:0019086 late viral transcription(GO:0019086)
0.3 3.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.3 1.3 GO:0021936 regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.3 9.3 GO:0021762 substantia nigra development(GO:0021762)
0.3 30.9 GO:0097485 neuron projection guidance(GO:0097485)
0.3 9.0 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.2 1.2 GO:0090168 Golgi reassembly(GO:0090168)
0.2 1.4 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 0.5 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.2 1.6 GO:0006824 cobalt ion transport(GO:0006824)
0.2 1.7 GO:0009642 response to light intensity(GO:0009642)
0.2 0.4 GO:0021626 hindbrain maturation(GO:0021578) cerebellum maturation(GO:0021590) central nervous system maturation(GO:0021626) cerebellar cortex maturation(GO:0021699)
0.2 1.1 GO:0048254 snoRNA localization(GO:0048254)
0.2 3.2 GO:0042574 retinal metabolic process(GO:0042574)
0.2 1.4 GO:0010815 bradykinin catabolic process(GO:0010815)
0.2 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 1.1 GO:0051036 regulation of endosome size(GO:0051036)
0.2 5.8 GO:0030199 collagen fibril organization(GO:0030199)
0.2 1.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 2.3 GO:0001502 cartilage condensation(GO:0001502)
0.2 2.7 GO:0019236 response to pheromone(GO:0019236)
0.2 6.1 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.2 1.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 8.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.2 5.1 GO:0006270 DNA replication initiation(GO:0006270)
0.2 2.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 3.9 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.3 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 3.0 GO:0030239 myofibril assembly(GO:0030239)
0.1 1.3 GO:0007000 nucleolus organization(GO:0007000)
0.1 1.9 GO:0051601 exocyst localization(GO:0051601)
0.1 0.9 GO:0019388 galactose catabolic process(GO:0019388)
0.1 4.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.3 GO:0002118 aggressive behavior(GO:0002118)
0.1 2.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 11.4 GO:0007631 feeding behavior(GO:0007631)
0.1 4.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 3.7 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 0.9 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 12.1 GO:0050808 synapse organization(GO:0050808)
0.1 3.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 1.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 3.0 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.1 20.8 GO:0007015 actin filament organization(GO:0007015)
0.1 1.7 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 0.6 GO:0032288 myelin assembly(GO:0032288)
0.1 0.9 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.4 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 2.8 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.1 0.3 GO:0015838 amino-acid betaine transport(GO:0015838)
0.1 0.9 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.1 1.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 1.3 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.1 2.7 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.1 2.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 6.8 GO:0016358 dendrite development(GO:0016358)
0.1 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 7.3 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.9 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 1.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.5 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.4 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.9 GO:0022900 electron transport chain(GO:0022900)
0.0 0.3 GO:0030488 tRNA methylation(GO:0030488)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
39.4 197.2 GO:0099569 presynaptic cytoskeleton(GO:0099569)
23.5 141.0 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
19.3 115.7 GO:0044308 axonal spine(GO:0044308)
16.6 49.8 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
12.5 99.8 GO:0032584 growth cone membrane(GO:0032584)
11.6 69.5 GO:0033269 internode region of axon(GO:0033269)
10.9 109.3 GO:0098839 postsynaptic density membrane(GO:0098839)
10.4 62.6 GO:0042584 chromaffin granule membrane(GO:0042584)
8.5 25.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
7.9 31.8 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
6.4 64.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
6.4 57.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
6.0 24.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
5.0 115.7 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
5.0 59.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
5.0 14.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
4.8 96.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
4.6 18.4 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
4.5 54.5 GO:0043083 synaptic cleft(GO:0043083)
4.5 18.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
4.5 13.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
4.4 39.8 GO:0030314 junctional membrane complex(GO:0030314)
4.2 12.5 GO:0098982 glycine-gated chloride channel complex(GO:0016935) GABA-ergic synapse(GO:0098982)
3.9 15.7 GO:1990584 cardiac Troponin complex(GO:1990584)
3.9 27.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
3.6 58.3 GO:0005883 neurofilament(GO:0005883)
3.3 9.8 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
3.0 15.0 GO:0071797 LUBAC complex(GO:0071797)
3.0 32.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
2.8 30.9 GO:0044327 dendritic spine head(GO:0044327)
2.5 82.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
2.4 47.1 GO:0043194 axon initial segment(GO:0043194)
2.3 34.2 GO:0035253 ciliary rootlet(GO:0035253)
2.2 17.3 GO:0043203 axon hillock(GO:0043203)
2.0 14.3 GO:0071438 invadopodium membrane(GO:0071438)
2.0 73.3 GO:0032809 neuronal cell body membrane(GO:0032809)
2.0 8.1 GO:0097513 myosin II filament(GO:0097513)
2.0 371.3 GO:0043204 perikaryon(GO:0043204)
2.0 13.8 GO:0044305 calyx of Held(GO:0044305)
2.0 21.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
1.9 15.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.8 16.5 GO:0031209 SCAR complex(GO:0031209)
1.8 68.6 GO:0008180 COP9 signalosome(GO:0008180)
1.7 17.1 GO:0042788 polysomal ribosome(GO:0042788)
1.6 8.0 GO:0032133 chromosome passenger complex(GO:0032133)
1.5 4.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
1.3 5.3 GO:0071914 prominosome(GO:0071914)
1.3 14.4 GO:0072546 ER membrane protein complex(GO:0072546)
1.3 6.5 GO:0005927 muscle tendon junction(GO:0005927)
1.3 7.6 GO:0044294 dendritic growth cone(GO:0044294)
1.2 20.4 GO:0036038 MKS complex(GO:0036038)
1.1 27.4 GO:0060077 inhibitory synapse(GO:0060077)
1.1 5.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.1 43.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.0 12.5 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
1.0 6.1 GO:1990246 uniplex complex(GO:1990246)
1.0 4.0 GO:0070876 SOSS complex(GO:0070876)
1.0 6.8 GO:0090543 Flemming body(GO:0090543)
1.0 14.3 GO:0042734 presynaptic membrane(GO:0042734)
0.9 69.4 GO:0044291 cell-cell contact zone(GO:0044291)
0.9 10.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.9 9.6 GO:0032982 myosin filament(GO:0032982)
0.9 5.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.8 22.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.8 10.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.8 23.0 GO:0097228 sperm principal piece(GO:0097228)
0.8 7.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.7 3.7 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.7 10.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.7 20.7 GO:0043034 costamere(GO:0043034)
0.7 73.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.7 194.4 GO:0060076 excitatory synapse(GO:0060076)
0.7 7.0 GO:0034704 calcium channel complex(GO:0034704)
0.7 2.7 GO:1990745 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.7 79.5 GO:0044306 neuron projection terminus(GO:0044306)
0.7 5.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.7 3.3 GO:0048179 activin receptor complex(GO:0048179)
0.6 1.9 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.6 10.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.6 6.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.6 178.3 GO:0030424 axon(GO:0030424)
0.6 24.5 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.6 5.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 1.6 GO:1990923 PET complex(GO:1990923)
0.5 4.2 GO:0016589 NURF complex(GO:0016589)
0.5 31.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.5 8.3 GO:0031430 M band(GO:0031430)
0.5 4.9 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.5 1.9 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.5 12.3 GO:0002080 acrosomal membrane(GO:0002080)
0.5 1.4 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.5 44.1 GO:0031225 anchored component of membrane(GO:0031225)
0.5 0.9 GO:0045025 mitochondrial degradosome(GO:0045025)
0.4 6.6 GO:0035102 PRC1 complex(GO:0035102)
0.4 11.1 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.4 30.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.4 2.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.4 47.9 GO:0005795 Golgi stack(GO:0005795)
0.4 3.2 GO:0005610 laminin-5 complex(GO:0005610)
0.4 13.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.4 3.6 GO:0030131 clathrin adaptor complex(GO:0030131) filopodium tip(GO:0032433)
0.4 0.4 GO:0030478 actin cap(GO:0030478)
0.4 2.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.4 22.2 GO:0030018 Z disc(GO:0030018)
0.4 4.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4 11.2 GO:0002102 podosome(GO:0002102)
0.4 26.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4 10.4 GO:0030315 T-tubule(GO:0030315)
0.4 2.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.3 16.7 GO:0045171 intercellular bridge(GO:0045171)
0.3 15.6 GO:0016592 mediator complex(GO:0016592)
0.3 0.9 GO:0032398 MHC class Ib protein complex(GO:0032398)
0.3 33.4 GO:0030027 lamellipodium(GO:0030027)
0.3 5.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 37.0 GO:0043209 myelin sheath(GO:0043209)
0.3 14.4 GO:0005884 actin filament(GO:0005884)
0.3 4.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 2.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 4.0 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.2 11.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 3.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 44.8 GO:0043025 neuronal cell body(GO:0043025)
0.2 1.5 GO:0070449 elongin complex(GO:0070449)
0.2 9.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 2.0 GO:0070652 HAUS complex(GO:0070652)
0.2 3.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 1.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.2 33.4 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.2 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 13.0 GO:0005814 centriole(GO:0005814)
0.1 16.8 GO:0001650 fibrillar center(GO:0001650)
0.1 7.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 2.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.3 GO:0034709 methylosome(GO:0034709)
0.1 2.4 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 7.6 GO:0005923 bicellular tight junction(GO:0005923)
0.1 2.7 GO:0031519 PcG protein complex(GO:0031519)
0.1 1.0 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 2.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.5 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.3 GO:0016459 myosin complex(GO:0016459)
0.0 1.0 GO:0031252 cell leading edge(GO:0031252)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
42.0 168.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
18.3 55.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
16.2 64.7 GO:0035727 lysophosphatidic acid binding(GO:0035727)
16.1 64.4 GO:0070699 type II activin receptor binding(GO:0070699)
15.4 77.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
13.3 66.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
13.3 66.3 GO:0043532 angiostatin binding(GO:0043532)
12.8 64.0 GO:0008502 melatonin receptor activity(GO:0008502)
12.5 62.6 GO:0030348 syntaxin-3 binding(GO:0030348)
12.3 98.2 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
10.8 54.0 GO:0005042 netrin receptor activity(GO:0005042)
10.7 42.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
10.3 71.8 GO:0004111 creatine kinase activity(GO:0004111)
8.8 26.3 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827)
8.4 84.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
6.3 18.8 GO:0030158 protein xylosyltransferase activity(GO:0030158)
6.2 49.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
6.0 181.1 GO:0017075 syntaxin-1 binding(GO:0017075)
5.4 43.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
5.3 15.9 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
5.1 15.4 GO:0016403 dimethylargininase activity(GO:0016403)
5.1 20.3 GO:0008940 nitrate reductase activity(GO:0008940)
5.0 89.7 GO:0005522 profilin binding(GO:0005522)
4.9 39.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
4.9 58.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
4.8 14.4 GO:0033222 xylose binding(GO:0033222)
4.8 14.4 GO:0042015 interleukin-20 binding(GO:0042015)
4.2 76.3 GO:0004890 GABA-A receptor activity(GO:0004890)
4.2 16.9 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
4.2 12.5 GO:0022852 glycine-gated chloride ion channel activity(GO:0022852)
4.1 32.9 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
3.9 110.3 GO:0005540 hyaluronic acid binding(GO:0005540)
3.9 15.7 GO:0030172 troponin C binding(GO:0030172)
3.7 14.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
3.7 18.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
3.6 86.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
3.6 96.6 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
3.5 31.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
3.4 17.2 GO:0004962 endothelin receptor activity(GO:0004962)
3.4 10.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
3.4 34.2 GO:0034190 apolipoprotein receptor binding(GO:0034190)
3.4 10.1 GO:0098603 selenol Se-methyltransferase activity(GO:0098603)
3.3 13.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
3.3 19.9 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
3.3 13.2 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
3.3 16.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
3.2 31.8 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
2.9 26.3 GO:0043559 insulin binding(GO:0043559)
2.9 14.3 GO:0015252 hydrogen ion channel activity(GO:0015252)
2.8 16.8 GO:0001515 opioid peptide activity(GO:0001515)
2.7 32.8 GO:0004000 adenosine deaminase activity(GO:0004000)
2.7 172.6 GO:0005080 protein kinase C binding(GO:0005080)
2.7 8.0 GO:0044736 acid-sensing ion channel activity(GO:0044736)
2.6 15.6 GO:0001849 complement component C1q binding(GO:0001849)
2.6 59.4 GO:0002162 dystroglycan binding(GO:0002162)
2.5 10.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
2.5 12.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
2.5 14.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
2.4 7.2 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489) ornithine decarboxylase activator activity(GO:0042978)
2.4 32.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
2.3 7.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
2.3 6.8 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
2.2 6.7 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
2.2 15.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
2.1 29.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
2.0 13.7 GO:0043237 laminin-1 binding(GO:0043237)
2.0 27.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.9 24.2 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
1.8 5.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607) H3 histone acetyltransferase activity(GO:0010484)
1.8 38.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.7 12.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.7 6.8 GO:0042610 CD8 receptor binding(GO:0042610)
1.7 6.7 GO:0019870 potassium channel inhibitor activity(GO:0019870)
1.6 11.4 GO:0045503 dynein light chain binding(GO:0045503)
1.6 14.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.6 41.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.6 1.6 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
1.6 8.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
1.6 1.6 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
1.6 7.9 GO:0004969 histamine receptor activity(GO:0004969)
1.6 18.9 GO:0019869 chloride channel inhibitor activity(GO:0019869)
1.5 10.8 GO:0016413 O-acetyltransferase activity(GO:0016413)
1.5 44.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.5 26.0 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
1.5 4.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.4 12.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.4 28.4 GO:0005123 death receptor binding(GO:0005123)
1.3 10.7 GO:0036122 BMP binding(GO:0036122)
1.3 46.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
1.2 4.9 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
1.2 7.3 GO:0004144 2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
1.2 4.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
1.2 9.4 GO:0030274 LIM domain binding(GO:0030274)
1.2 29.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.2 25.6 GO:0003746 translation elongation factor activity(GO:0003746)
1.2 5.8 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
1.1 4.5 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
1.1 6.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.1 19.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
1.1 3.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
1.1 9.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
1.0 3.0 GO:0051373 FATZ binding(GO:0051373)
1.0 3.9 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.9 25.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.9 9.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.9 5.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.8 39.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.8 7.1 GO:0015266 protein channel activity(GO:0015266)
0.8 27.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.8 3.9 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.8 2.3 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.8 6.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.8 12.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.7 10.7 GO:0031005 filamin binding(GO:0031005)
0.7 2.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.7 7.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.7 4.2 GO:1990239 steroid hormone binding(GO:1990239)
0.7 4.0 GO:0000150 recombinase activity(GO:0000150)
0.7 7.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.6 11.0 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.6 5.1 GO:0045545 syndecan binding(GO:0045545)
0.6 7.6 GO:0033691 sialic acid binding(GO:0033691)
0.6 5.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.6 5.0 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.6 10.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.6 90.3 GO:0051015 actin filament binding(GO:0051015)
0.6 10.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.6 17.1 GO:0030371 translation repressor activity(GO:0030371)
0.6 6.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.5 3.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.5 4.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.5 13.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.5 5.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.5 5.8 GO:0050811 GABA receptor binding(GO:0050811)
0.5 14.3 GO:0030507 spectrin binding(GO:0030507)
0.5 15.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.5 7.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.5 7.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.5 1.4 GO:0004946 bombesin receptor activity(GO:0004946)
0.5 11.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.5 2.3 GO:0042731 PH domain binding(GO:0042731)
0.4 24.0 GO:0032947 protein complex scaffold(GO:0032947)
0.4 32.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.4 131.0 GO:0015631 tubulin binding(GO:0015631)
0.4 3.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.4 2.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923) GPI anchor binding(GO:0034235)
0.4 4.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.4 3.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.4 11.6 GO:0019894 kinesin binding(GO:0019894)
0.4 4.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.4 46.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 5.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.4 1.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.4 16.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3 1.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.3 1.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 5.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.3 2.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 3.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 24.7 GO:0008565 protein transporter activity(GO:0008565)
0.3 0.8 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.2 2.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 25.4 GO:0005516 calmodulin binding(GO:0005516)
0.2 1.2 GO:0071253 connexin binding(GO:0071253)
0.2 0.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 1.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 5.3 GO:0042805 actinin binding(GO:0042805)
0.2 5.5 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.2 4.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 2.4 GO:0019215 intermediate filament binding(GO:0019215)
0.2 2.9 GO:0004659 prenyltransferase activity(GO:0004659)
0.2 0.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 0.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 39.7 GO:0005096 GTPase activator activity(GO:0005096)
0.2 2.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.2 14.6 GO:0030165 PDZ domain binding(GO:0030165)
0.2 1.1 GO:0008432 JUN kinase binding(GO:0008432)
0.1 2.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 2.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 10.6 GO:0044325 ion channel binding(GO:0044325)
0.1 1.5 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 1.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 6.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 3.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 2.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 6.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 11.3 GO:0005179 hormone activity(GO:0005179)
0.1 3.7 GO:0004601 peroxidase activity(GO:0004601)
0.1 2.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 4.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 7.6 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.8 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 2.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 2.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 7.3 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0016594 glycine binding(GO:0016594)
0.0 1.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.3 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.2 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 163.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
2.6 112.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
2.6 33.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
2.4 60.7 PID NETRIN PATHWAY Netrin-mediated signaling events
2.3 79.2 PID NCADHERIN PATHWAY N-cadherin signaling events
2.2 116.5 PID EPHB FWD PATHWAY EPHB forward signaling
1.5 44.8 PID REELIN PATHWAY Reelin signaling pathway
1.0 9.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
1.0 49.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.9 15.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.9 13.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.8 9.8 PID ALK2 PATHWAY ALK2 signaling events
0.8 10.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.8 15.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.8 15.9 ST GA13 PATHWAY G alpha 13 Pathway
0.8 47.4 PID LKB1 PATHWAY LKB1 signaling events
0.7 28.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.7 7.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.6 13.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.6 4.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.5 10.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.5 13.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.5 17.4 PID FGF PATHWAY FGF signaling pathway
0.4 9.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.4 7.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.4 8.3 PID ARF 3PATHWAY Arf1 pathway
0.4 5.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.4 8.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.4 8.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.4 9.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.4 23.1 PID AP1 PATHWAY AP-1 transcription factor network
0.3 3.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 2.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 9.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 3.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 8.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 13.6 PID NOTCH PATHWAY Notch signaling pathway
0.2 40.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 3.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 5.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 5.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
12.4 223.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
9.2 128.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
6.8 114.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
5.4 53.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
5.3 84.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
3.6 106.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
3.4 119.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
3.4 71.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
3.1 70.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
2.9 35.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
2.8 8.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
2.6 39.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
2.4 16.8 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
2.3 44.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
2.1 29.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
1.7 31.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.5 22.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
1.5 11.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.3 30.1 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
1.3 12.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.2 13.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
1.2 33.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
1.2 18.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
1.2 14.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
1.2 19.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.9 11.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.9 11.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.8 62.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.8 14.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.8 10.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.7 20.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.7 9.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.7 15.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.6 10.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.6 6.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.6 23.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.6 5.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.6 21.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.5 21.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.5 20.0 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.5 9.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.5 12.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.5 23.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.5 8.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.4 22.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.4 3.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.4 20.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 14.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.4 3.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.3 10.3 REACTOME KINESINS Genes involved in Kinesins
0.3 7.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 4.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 4.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 7.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 12.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 5.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.3 8.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.3 2.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 7.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 9.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.2 3.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 10.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 13.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 2.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 3.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 3.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.2 4.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.2 2.3 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 3.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 7.7 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 11.5 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.1 3.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 3.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 3.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 2.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 5.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)