Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Evx2

Z-value: 0.43

Motif logo

logo of

Transcription factors associated with Evx2

Gene Symbol Gene ID Gene Info
Evx2
ENSRNOG00000001589 even-skipped homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Evx2rn6_v1_chr3_-_61581598_615815980.475.1e-19Click!

Activity profile of Evx2 motif

Sorted Z-values of Evx2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_28485619 18.29 ENSRNOT00000093341
ENSRNOT00000093129
LOC100912373
uncharacterized LOC100912373
chr11_+_58624198 15.57 ENSRNOT00000002091
Gap43
growth associated protein 43
chr12_-_19167015 14.16 ENSRNOT00000001797
Gjc3
gap junction protein, gamma 3
chr1_+_59156251 13.69 ENSRNOT00000017442
Lix1
limb and CNS expressed 1
chr8_-_45137893 13.13 ENSRNOT00000010743
RGD1309108
similar to hypothetical protein FLJ23554
chr1_-_227457629 11.98 ENSRNOT00000035910
ENSRNOT00000073770
Ms4a5
membrane spanning 4-domains A5
chr2_+_66940057 11.21 ENSRNOT00000043050
Cdh9
cadherin 9
chr12_-_2174131 10.99 ENSRNOT00000001313
Pcp2
Purkinje cell protein 2
chr7_-_113228439 10.31 ENSRNOT00000034672
Col22a1
collagen type XXII alpha 1 chain
chr9_-_30844199 9.96 ENSRNOT00000017169
Col19a1
collagen type XIX alpha 1 chain
chr1_-_189238776 9.79 ENSRNOT00000020817
Pdilt
protein disulfide isomerase-like, testis expressed
chr3_-_120076788 9.59 ENSRNOT00000047158
Kcnip3
potassium voltage-gated channel interacting protein 3
chr10_-_88670430 9.33 ENSRNOT00000025547
Hcrt
hypocretin neuropeptide precursor
chr4_+_70977556 7.88 ENSRNOT00000031984
LOC680112
hypothetical protein LOC680112
chr2_-_132301073 7.57 ENSRNOT00000058288
RGD1563562
similar to GTPase activating protein testicular GAP1
chr13_+_89480058 7.48 ENSRNOT00000050804
Cfap126
cilia and flagella associated protein 126
chr1_-_215033460 7.45 ENSRNOT00000044565
Dusp8
dual specificity phosphatase 8
chr12_-_35979193 7.08 ENSRNOT00000071104
Tmem132b
transmembrane protein 132B
chr14_-_115052450 7.05 ENSRNOT00000067998
Acyp2
acylphosphatase 2
chr11_-_61234944 6.68 ENSRNOT00000059680
Cfap44
cilia and flagella associated protein 44
chr7_-_76488216 6.47 ENSRNOT00000080024
Ncald
neurocalcin delta
chr16_+_12955826 6.37 ENSRNOT00000060751
4930596D02Rik
RIKEN cDNA 4930596D02 gene
chr16_+_51748970 6.22 ENSRNOT00000059182
Adam26a
a disintegrin and metallopeptidase domain 26A
chr1_+_129613497 6.13 ENSRNOT00000074410
LOC102551255
tetraspanin-7-like
chr1_+_98414226 5.91 ENSRNOT00000090785
Siglecl1
SIGLEC family like 1
chr18_+_4084228 5.77 ENSRNOT00000071392
Cabyr
calcium binding tyrosine phosphorylation regulated
chr3_+_56056925 5.53 ENSRNOT00000088351
ENSRNOT00000010508
Klhl23
kelch-like family member 23
chr5_+_61474000 5.31 ENSRNOT00000013930
Ccdc180
coiled-coil domain containing 180
chr18_+_30017918 5.23 ENSRNOT00000079794
Pcdha4
protocadherin alpha 4
chr3_+_113319456 5.13 ENSRNOT00000051354
Ckmt1
creatine kinase, mitochondrial 1
chr1_-_81550598 4.33 ENSRNOT00000051671
RGD1564380
similar to BC049730 protein
chr13_+_51229890 3.68 ENSRNOT00000060669
Cyb5r1
cytochrome b5 reductase 1
chr7_-_28711761 3.67 ENSRNOT00000006249
Parpbp
PARP1 binding protein
chr3_+_80072489 3.40 ENSRNOT00000057176
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chrX_-_134866210 3.35 ENSRNOT00000005331
Apln
apelin
chr18_-_16543992 3.21 ENSRNOT00000036306
Slc39a6
solute carrier family 39 member 6
chr3_-_124879216 3.04 ENSRNOT00000028886
Tmem230
transmembrane protein 230
chr8_-_83280888 3.02 ENSRNOT00000052341
Gfral
GDNF family receptor alpha like
chr12_+_41486076 2.79 ENSRNOT00000057242
Rita1
RBPJ interacting and tubulin associated 1
chr7_+_6644643 2.78 ENSRNOT00000051670
Olr962
olfactory receptor 962
chr1_+_185863043 2.54 ENSRNOT00000079072
Sox6
SRY box 6
chr13_+_90514336 2.39 ENSRNOT00000088996
ENSRNOT00000085377
Pex19
peroxisomal biogenesis factor 19
chr8_+_126975833 2.23 ENSRNOT00000088348
AABR07071701.1

chr19_+_45938915 2.20 ENSRNOT00000065508
Mon1b
MON1 homolog B, secretory trafficking associated
chr1_+_99888297 1.99 ENSRNOT00000080896
AABR07003241.3

chr8_+_57983556 1.94 ENSRNOT00000009562
RGD1311251
similar to RIKEN cDNA 4930550C14
chr2_-_219262901 1.91 ENSRNOT00000037068
Gpr88
G-protein coupled receptor 88
chr5_+_117583502 1.78 ENSRNOT00000010933
Usp1
ubiquitin specific peptidase 1
chr10_-_43931094 1.73 ENSRNOT00000039778
Olr1415
olfactory receptor 1415
chr2_+_252090669 1.69 ENSRNOT00000020656
Lpar3
lysophosphatidic acid receptor 3
chr1_-_261179790 1.58 ENSRNOT00000074420
ENSRNOT00000072073
Exosc1
exosome component 1
chr7_-_143967484 1.53 ENSRNOT00000081758
Sp7
Sp7 transcription factor
chr5_-_151473750 1.45 ENSRNOT00000011357
Tmem222
transmembrane protein 222
chr1_+_261180007 1.43 ENSRNOT00000072181
Zdhhc16
zinc finger, DHHC-type containing 16
chrX_+_110016995 1.41 ENSRNOT00000093542
Nrk
Nik related kinase
chr17_-_52477575 1.40 ENSRNOT00000081290
Gli3
GLI family zinc finger 3
chr1_-_88657845 1.40 ENSRNOT00000074211
LOC100912380
calpain small subunit 1-like
chr17_-_34945317 1.18 ENSRNOT00000090457
Vma21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr14_+_77922045 1.11 ENSRNOT00000081198
Stk32b
serine/threonine kinase 32B
chr17_-_87826421 1.03 ENSRNOT00000068156
Arhgap21
Rho GTPase activating protein 21
chr15_-_12889102 0.91 ENSRNOT00000061214
ENSRNOT00000084687
RGD1306063
similar to HT021
chr20_-_323703 0.88 ENSRNOT00000089844
Olr1668
olfactory receptor 1668
chr4_+_71836677 0.88 ENSRNOT00000024048
Tas2r126
taste receptor, type 2, member 126
chrX_+_15113878 0.67 ENSRNOT00000007464
Wdr13
WD repeat domain 13
chr15_-_93748742 0.65 ENSRNOT00000093370
Mycbp2
MYC binding protein 2, E3 ubiquitin protein ligase
chr3_-_133131192 0.56 ENSRNOT00000055630
Tasp1
taspase 1
chr13_-_73638073 0.54 ENSRNOT00000005195
Cep350
centrosomal protein 350
chr10_-_10881844 0.53 ENSRNOT00000087118
ENSRNOT00000004416
Mgrn1
mahogunin ring finger 1
chrX_-_65102344 0.52 ENSRNOT00000016042
ENSRNOT00000075875
Las1l
LAS1-like, ribosome biogenesis factor
chr20_+_7409401 0.45 ENSRNOT00000000586
Snrpc
small nuclear ribonucleoprotein polypeptide C
chrX_+_140878216 0.45 ENSRNOT00000075840
ENSRNOT00000077026
Zic3
Zic family member 3
chr12_-_48627297 0.45 ENSRNOT00000000890
Iscu
iron-sulfur cluster assembly enzyme
chr17_+_9797907 0.37 ENSRNOT00000021638
Lman2
lectin, mannose-binding 2
chr8_-_19773243 0.33 ENSRNOT00000040848
Olr1155
olfactory receptor 1155
chr17_-_27279260 0.32 ENSRNOT00000018508
Snrnp48
small nuclear ribonucleoprotein U11/U12 subunit 48
chr15_-_12129220 0.30 ENSRNOT00000029318
Olr1605
olfactory receptor 1605
chr16_-_70242979 0.30 ENSRNOT00000071269
LOC103689964
vacuolar ATPase assembly integral membrane protein Vma21
chr20_+_12944786 0.28 ENSRNOT00000048218
Pcnt
pericentrin
chr8_+_107495366 0.25 ENSRNOT00000056590
Cep70
centrosomal protein 70
chr13_+_90943255 0.21 ENSRNOT00000011539
Vsig8
V-set and immunoglobulin domain containing 8
chr1_+_189432604 0.17 ENSRNOT00000034610
Acsm4
acyl-CoA synthetase medium-chain family member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Evx2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 15.6 GO:0016198 axon choice point recognition(GO:0016198)
1.4 11.0 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
1.2 9.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.9 18.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.8 3.3 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.7 2.2 GO:0019086 late viral transcription(GO:0019086)
0.7 9.8 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.5 2.4 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.4 2.5 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.4 13.7 GO:0097352 autophagosome maturation(GO:0097352)
0.4 1.9 GO:0061743 motor learning(GO:0061743)
0.4 3.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 1.4 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.3 9.6 GO:0048266 behavioral response to pain(GO:0048266)
0.3 3.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.3 6.7 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.3 7.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.3 1.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 1.4 GO:0060721 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.2 3.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.8 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 1.5 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 16.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.7 GO:0032060 bleb assembly(GO:0032060)
0.1 14.2 GO:0042552 myelination(GO:0042552)
0.1 0.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 2.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 3.0 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 3.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 0.5 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.7 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 6.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 12.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.6 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 1.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 7.5 GO:0044782 cilium organization(GO:0044782)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 2.2 GO:0097480 synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480)
0.0 0.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 15.6 GO:0032584 growth cone membrane(GO:0032584)
0.7 14.2 GO:0005922 connexon complex(GO:0005922)
0.3 5.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 3.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 9.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 9.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 5.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 7.8 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.5 GO:0000243 commitment complex(GO:0000243)
0.0 2.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 3.0 GO:0005776 autophagosome(GO:0005776)
0.0 11.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 5.1 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 3.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 11.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 15.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
1.5 18.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
1.2 9.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.8 1.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.7 5.1 GO:0004111 creatine kinase activity(GO:0004111)
0.6 3.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.5 7.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 2.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.3 12.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 3.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 6.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 9.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.5 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 3.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.5 GO:0030619 U1 snRNA binding(GO:0030619) U1 snRNP binding(GO:1990446)
0.0 11.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 17.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 13.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 1.9 GO:0003774 motor activity(GO:0003774)
0.0 3.3 GO:0015631 tubulin binding(GO:0015631)
0.0 1.4 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 15.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 15.2 NABA COLLAGENS Genes encoding collagen proteins
0.2 7.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.4 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 11.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 20.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 1.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 3.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 11.0 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events