ISMARA results: Etv3_Erf_Fev_Elk4_Elk1

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Etv3_Erf_Fev_Elk4_Elk1_Elk3

Z-value: 2.64

Motif logo

Transcription factors associated with Etv3_Erf_Fev_Elk4_Elk1_Elk3

Gene Symbol	Gene ID	Gene Info
Etv3 NCBI RGD Ensembl	ENSRNOG00000043095	ets variant 3
Erf NCBI RGD Ensembl	ENSRNOG00000020426	Ets2 repressor factor
Fev NCBI RGD Ensembl	ENSRNOG00000017856	FEV, ETS transcription factor
Elk4 NCBI RGD Ensembl	ENSRNOG00000007887	ELK4, ETS transcription factor
Elk1 NCBI RGD Ensembl	ENSRNOG00000010171	ELK1, ETS transcription factor
Elk3 NCBI RGD Ensembl	ENSRNOG00000004367	ELK3, ETS-domain protein

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Elk4	rn6_v1_chr13_+_48790951_48790951	-0.85	1.3e-89	Click!
Etv3	rn6_v1_chr2_+_186872520_186872572	-0.78	7.4e-66	Click!
Elk3	rn6_v1_chr7_-_34121694_34121694	-0.52	1.5e-23	Click!
Elk1	rn6_v1_chrX_+_1297099_1297099	0.32	3.4e-09	Click!
Fev	rn6_v1_chr9_-_82146874_82146874	0.12	3.2e-02	Click!
Erf	rn6_v1_chr1_-_82120902_82120902	-0.02	6.7e-01	Click!

Activity profile of Etv3_Erf_Fev_Elk4_Elk1_Elk3 motif

Sorted Z-values of Etv3_Erf_Fev_Elk4_Elk1_Elk3 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_-_34166599 Show fit	260.79	ENSRNOT00000003246	Trim41 NCBI RGD Ensembl Show fit	tripartite motif-containing 41
chr8_-_65587427 Show fit	159.49	ENSRNOT00000016491	Lrrc49 NCBI RGD Ensembl Show fit	leucine rich repeat containing 49
chr13_-_37287458 Show fit	142.63	ENSRNOT00000003391	Insig2 NCBI RGD Ensembl Show fit	insulin induced gene 2
chr8_-_65587658 Show fit	134.50	ENSRNOT00000091982	Lrrc49 NCBI RGD Ensembl Show fit	leucine rich repeat containing 49
chr20_+_5125349 Show fit	104.95	ENSRNOT00000085598 ENSRNOT00000001129	Bag6 NCBI RGD Ensembl Show fit	BCL2-associated athanogene 6
chr6_+_104291071 Show fit	99.00	ENSRNOT00000006798	Slc39a9 NCBI RGD Ensembl Show fit	solute carrier family 39, member 9
chr15_-_34352673 Show fit	93.98	ENSRNOT00000064916	Nedd8 NCBI RGD Ensembl Show fit	neural precursor cell expressed, developmentally down-regulated 8
chr2_+_115337439 Show fit	90.83	ENSRNOT00000015779	Eif5a2 NCBI RGD Ensembl Show fit	eukaryotic translation initiation factor 5A2
chr6_-_104290579 Show fit	87.48	ENSRNOT00000066014	Erh NCBI RGD Ensembl Show fit	enhancer of rudimentary homolog (Drosophila)
chr16_+_21275311 Show fit	85.25	ENSRNOT00000027980	LOC100911483 NCBI RGD Ensembl Show fit	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-like
chr3_-_168018410 Show fit	84.49	ENSRNOT00000087579	Bcas1 NCBI RGD Ensembl Show fit	breast carcinoma amplified sequence 1
chr2_-_18927365 Show fit	83.18	ENSRNOT00000045850	Xrcc4 NCBI RGD Ensembl Show fit	X-ray repair cross complementing 4
chr20_+_5455974 Show fit	82.63	ENSRNOT00000000553 ENSRNOT00000092676	Pfdn6 NCBI RGD Ensembl Show fit	prefoldin subunit 6
chr10_-_27366665 Show fit	81.83	ENSRNOT00000004725	Gabra1 NCBI RGD Ensembl Show fit	gamma-aminobutyric acid type A receptor alpha1 subunit
chr19_+_56010085 Show fit	79.62	ENSRNOT00000058216	Spata33 NCBI RGD Ensembl Show fit	spermatogenesis associated 33
chr20_+_6869767 Show fit	79.15	ENSRNOT00000000631 ENSRNOT00000086330 ENSRNOT00000093188 ENSRNOT00000093736	RGD735065 NCBI RGD Ensembl Show fit	similar to GI:13385412-like protein splice form I
chr3_+_60024013 Show fit	78.74	ENSRNOT00000025255	Scrn3 NCBI RGD Ensembl Show fit	secernin 3
chr10_+_14094754 Show fit	78.32	ENSRNOT00000019660	Rpl3l NCBI RGD Ensembl Show fit	ribosomal protein L3-like
chr7_-_119158173 Show fit	75.61	ENSRNOT00000067483 ENSRNOT00000078528	Txn2 NCBI RGD Ensembl Show fit	thioredoxin 2
chr3_+_80555196 Show fit	75.28	ENSRNOT00000067318	Arhgap1 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 1
chr15_-_4057104 Show fit	75.23	ENSRNOT00000084350 ENSRNOT00000012270	Sec24c NCBI RGD Ensembl Show fit	SEC24 homolog C, COPII coat complex component
chr16_+_71058022 Show fit	72.74	ENSRNOT00000066901	Bag4 NCBI RGD Ensembl Show fit	BCL2-associated athanogene 4
chr1_+_225120061 Show fit	71.35	ENSRNOT00000026875	B3gat3 NCBI RGD Ensembl Show fit	beta-1,3-glucuronyltransferase 3
chr20_-_5441706 Show fit	66.53	ENSRNOT00000000549	Vps52 NCBI RGD Ensembl Show fit	VPS52 GARP complex subunit
chr19_-_11451278 Show fit	64.72	ENSRNOT00000026118	Ogfod1 NCBI RGD Ensembl Show fit	2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr20_+_5125679 Show fit	64.36	ENSRNOT00000060832	Bag6 NCBI RGD Ensembl Show fit	BCL2-associated athanogene 6
chr5_+_142702685 Show fit	63.25	ENSRNOT00000085986 ENSRNOT00000010373 ENSRNOT00000087416	Sf3a3 NCBI RGD Ensembl Show fit	splicing factor 3a, subunit 3
chr6_-_108076186 Show fit	63.22	ENSRNOT00000014814	Fam161b NCBI RGD Ensembl Show fit	family with sequence similarity 161, member B
chr11_+_64790801 Show fit	62.39	ENSRNOT00000004023	Timmdc1 NCBI RGD Ensembl Show fit	translocase of inner mitochondrial membrane domain containing 1
chrX_+_26294066 Show fit	62.09	ENSRNOT00000037862	Hccs NCBI RGD Ensembl Show fit	holocytochrome c synthase
chr9_-_23352668 Show fit	61.05	ENSRNOT00000075279	Mut NCBI RGD Ensembl Show fit	methylmalonyl CoA mutase
chr13_-_89668473 Show fit	61.05	ENSRNOT00000004938	Ufc1 NCBI RGD Ensembl Show fit	ubiquitin-fold modifier conjugating enzyme 1
chr8_+_70522092 Show fit	60.69	ENSRNOT00000025873	Dpp8 NCBI RGD Ensembl Show fit	dipeptidylpeptidase 8
chr3_-_151688149 Show fit	60.40	ENSRNOT00000072945	Nfs1 NCBI RGD Ensembl Show fit	NFS1 cysteine desulfurase
chr17_-_79798435 Show fit	60.10	ENSRNOT00000022986	Fam188a NCBI RGD Ensembl Show fit	family with sequence similarity 188, member A
chr11_-_27080701 Show fit	60.05	ENSRNOT00000002180	Ltn1 NCBI RGD Ensembl Show fit	listerin E3 ubiquitin protein ligase 1
chr4_+_27647335 Show fit	59.64	ENSRNOT00000067376	Gatad1 NCBI RGD Ensembl Show fit	GATA zinc finger domain containing 1
chr6_+_108936664 Show fit	58.45	ENSRNOT00000007298	Dlst NCBI RGD Ensembl Show fit	dihydrolipoamide S-succinyltransferase
chr15_+_12407524 Show fit	58.18	ENSRNOT00000009249	Psmd6 NCBI RGD Ensembl Show fit	proteasome 26S subunit, non-ATPase 6
chr19_+_37282018 Show fit	57.79	ENSRNOT00000021723	Tmem208 NCBI RGD Ensembl Show fit	transmembrane protein 208
chr4_-_9881484 Show fit	57.51	ENSRNOT00000016450	Psmc2 NCBI RGD Ensembl Show fit	proteasome 26S subunit, ATPase 2
chr6_-_64170122 Show fit	57.34	ENSRNOT00000093248 ENSRNOT00000005363	Dnajb9 NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member B9
chr3_-_79728879 Show fit	56.98	ENSRNOT00000012425	Ndufs3 NCBI RGD Ensembl Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 3
chr15_-_57805184 Show fit	56.79	ENSRNOT00000000168	Cog3 NCBI RGD Ensembl Show fit	component of oligomeric golgi complex 3
chr6_-_8346197 Show fit	56.58	ENSRNOT00000061826	Prepl NCBI RGD Ensembl Show fit	prolyl endopeptidase-like
chr10_-_74001895 Show fit	54.83	ENSRNOT00000005658	Vmp1 NCBI RGD Ensembl Show fit	vacuole membrane protein 1
chr3_-_152222647 Show fit	53.30	ENSRNOT00000026820	Nfs1 NCBI RGD Ensembl Show fit	NFS1 cysteine desulfurase
chr9_+_94879745 Show fit	53.29	ENSRNOT00000080482	Atg16l1 NCBI RGD Ensembl Show fit	autophagy related 16-like 1
chr4_+_118655728 Show fit	52.98	ENSRNOT00000043082	Aak1 NCBI RGD Ensembl Show fit	AP2 associated kinase 1
chr17_+_15966234 Show fit	52.84	ENSRNOT00000084304	Wnk2 NCBI RGD Ensembl Show fit	WNK lysine deficient protein kinase 2
chr2_+_244521699 Show fit	51.25	ENSRNOT00000029382	Stpg2 NCBI RGD Ensembl Show fit	sperm-tail PG-rich repeat containing 2
chr1_+_142050458 Show fit	50.84	ENSRNOT00000018107	Ngrn NCBI RGD Ensembl Show fit	neugrin, neurite outgrowth associated
chr6_-_22138286 Show fit	50.76	ENSRNOT00000007607	Yipf4 NCBI RGD Ensembl Show fit	Yip1 domain family, member 4
chr8_+_126411829 Show fit	50.72	ENSRNOT00000013450	Azi2 NCBI RGD Ensembl Show fit	5-azacytidine induced 2
chr8_+_21663325 Show fit	49.78	ENSRNOT00000027749	Ubl5 NCBI RGD Ensembl Show fit	ubiquitin-like 5
chr7_-_36408588 Show fit	49.54	ENSRNOT00000063946	Cradd NCBI RGD Ensembl Show fit	CASP2 and RIPK1 domain containing adaptor with death domain
chr1_-_48033343 Show fit	48.58	ENSRNOT00000019531 ENSRNOT00000076422	Tcp1 NCBI RGD Ensembl Show fit	t-complex 1
chr14_-_86333424 Show fit	48.28	ENSRNOT00000083191	Nudcd3 NCBI RGD Ensembl Show fit	NudC domain containing 3
chr7_+_26256459 Show fit	47.64	ENSRNOT00000010986	Appl2 NCBI RGD Ensembl Show fit	adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
chr8_+_49354115 Show fit	47.60	ENSRNOT00000032837	Mpzl3 NCBI RGD Ensembl Show fit	myelin protein zero-like 3
chr3_+_151688454 Show fit	47.43	ENSRNOT00000026856	Romo1 NCBI RGD Ensembl Show fit	reactive oxygen species modulator 1
chr3_+_152222726 Show fit	47.13	ENSRNOT00000072464	LOC100910944 NCBI RGD Ensembl Show fit	reactive oxygen species modulator 1-like
chr20_-_45005035 Show fit	46.94	ENSRNOT00000035047	Mfsd4b NCBI RGD Ensembl Show fit	major facilitator superfamily domain containing 4B
chr9_+_10846596 Show fit	46.41	ENSRNOT00000075386	Dpp9 NCBI RGD Ensembl Show fit	dipeptidyl peptidase 9
chr7_-_12918173 Show fit	46.25	ENSRNOT00000011010	Tpgs1 NCBI RGD Ensembl Show fit	tubulin polyglutamylase complex subunit 1
chr15_-_58711872 Show fit	45.95	ENSRNOT00000058204	Serp2 NCBI RGD Ensembl Show fit	stress-associated endoplasmic reticulum protein family member 2
chr9_-_99818262 Show fit	45.87	ENSRNOT00000056600	Cops9 NCBI RGD Ensembl Show fit	COP9 signalosome subunit 9
chr19_+_22281906 Show fit	45.71	ENSRNOT00000021711	Itfg1 NCBI RGD Ensembl Show fit	integrin alpha FG-GAP repeat containing 1
chr1_+_31576183 Show fit	45.48	ENSRNOT00000019735	Pdcd6 NCBI RGD Ensembl Show fit	programmed cell death 6
chr11_+_46179940 Show fit	45.23	ENSRNOT00000088152	Tfg NCBI RGD Ensembl Show fit	Trk-fused gene
chr16_-_2367253 Show fit	44.53	ENSRNOT00000083573	Pde12 NCBI RGD Ensembl Show fit	phosphodiesterase 12
chr9_-_69953182 Show fit	44.13	ENSRNOT00000015852	Ndufs1 NCBI RGD Ensembl Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr15_+_34352914 Show fit	43.85	ENSRNOT00000067150	Gmpr2 NCBI RGD Ensembl Show fit	guanosine monophosphate reductase 2
chr1_-_89084859 Show fit	43.67	ENSRNOT00000032026	Cox6b1 NCBI RGD Ensembl Show fit	cytochrome c oxidase subunit 6B1
chr11_+_83868655 Show fit	43.54	ENSRNOT00000072402	NEWGENE_621438 NCBI RGD Ensembl Show fit	thrombopoietin
chr13_-_82607379 Show fit	43.16	ENSRNOT00000051763	Blzf1 NCBI RGD Ensembl Show fit	basic leucine zipper nuclear factor 1
chr10_-_46206135 Show fit	42.54	ENSRNOT00000091471	Cops3 NCBI RGD Ensembl Show fit	COP9 signalosome subunit 3
chr3_-_122813583 Show fit	42.49	ENSRNOT00000009681	Idh3B NCBI RGD Ensembl Show fit	isocitrate dehydrogenase 3 (NAD+) beta
chr11_+_16826399 Show fit	42.33	ENSRNOT00000050701	Cxadr NCBI RGD Ensembl Show fit	coxsackie virus and adenovirus receptor
chr4_-_56897310 Show fit	41.87	ENSRNOT00000043902 ENSRNOT00000090038	Tnpo3 NCBI RGD Ensembl Show fit	transportin 3
chr6_+_34094306 Show fit	41.73	ENSRNOT00000051970	Wdr35 NCBI RGD Ensembl Show fit	WD repeat domain 35
chr19_+_551708 Show fit	41.52	ENSRNOT00000015811	Fam96b NCBI RGD Ensembl Show fit	family with sequence similarity 96, member B
chr1_+_192088672 Show fit	41.51	ENSRNOT00000024367	Dctn5 NCBI RGD Ensembl Show fit	dynactin subunit 5
chr1_-_165382216 Show fit	41.36	ENSRNOT00000023648	Ppme1 NCBI RGD Ensembl Show fit	protein phosphatase methylesterase 1
chr13_-_101697684 Show fit	41.32	ENSRNOT00000078834	Brox NCBI RGD Ensembl Show fit	BRO1 domain and CAAX motif containing
chr3_-_164986180 Show fit	41.23	ENSRNOT00000016150	Dpm1 NCBI RGD Ensembl Show fit	dolichyl-phosphate mannosyltransferase subunit 1, catalytic
chr2_+_218951451 Show fit	41.15	ENSRNOT00000019190	Extl2 NCBI RGD Ensembl Show fit	exostosin-like glycosyltransferase 2
chr10_-_86355006 Show fit	40.91	ENSRNOT00000075076	Pgap3 NCBI RGD Ensembl Show fit	post-GPI attachment to proteins 3
chr3_+_140106766 Show fit	40.43	ENSRNOT00000014046	Naa20 NCBI RGD Ensembl Show fit	N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr13_-_97838228 Show fit	40.43	ENSRNOT00000003618	Tfb2m NCBI RGD Ensembl Show fit	transcription factor B2, mitochondrial
chr17_+_47397558 Show fit	40.07	ENSRNOT00000085923	Epdr1 NCBI RGD Ensembl Show fit	ependymin related 1
chr20_-_38985036 Show fit	39.71	ENSRNOT00000001066	Serinc1 NCBI RGD Ensembl Show fit	serine incorporator 1
chr3_-_22951711 Show fit	39.40	ENSRNOT00000016876 ENSRNOT00000085981	Psmb7 NCBI RGD Ensembl Show fit	proteasome subunit beta 7
chr7_+_98813040 Show fit	39.32	ENSRNOT00000012616	Ndufb9 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit B9
chr3_+_94848823 Show fit	38.99	ENSRNOT00000041362	Ccdc73 NCBI RGD Ensembl Show fit	coiled-coil domain containing 73
chr17_+_5225835 Show fit	38.94	ENSRNOT00000022373	Zcchc6 NCBI RGD Ensembl Show fit	zinc finger CCHC-type containing 6
chr14_+_2325308 Show fit	38.91	ENSRNOT00000000072	Atp5i NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr19_+_52032886 Show fit	38.32	ENSRNOT00000019923	Mlycd NCBI RGD Ensembl Show fit	malonyl-CoA decarboxylase
chr12_+_19231092 Show fit	38.30	ENSRNOT00000045379	Zkscan1 NCBI RGD Ensembl Show fit	zinc finger with KRAB and SCAN domains 1
chr1_-_261140389 Show fit	37.97	ENSRNOT00000073193	Rrp12 NCBI RGD Ensembl Show fit	ribosomal RNA processing 12 homolog
chr1_-_174620064 Show fit	37.78	ENSRNOT00000016224	Tmem41b NCBI RGD Ensembl Show fit	transmembrane protein 41B
chr19_-_22281778 Show fit	37.74	ENSRNOT00000049624	Phkb NCBI RGD Ensembl Show fit	phosphorylase kinase regulatory subunit beta
chr10_+_82375572 Show fit	37.34	ENSRNOT00000004947	Mrpl27 NCBI RGD Ensembl Show fit	mitochondrial ribosomal protein L27
chr16_-_71057883 Show fit	37.15	ENSRNOT00000020721	Lsm1 NCBI RGD Ensembl Show fit	LSM1 homolog, mRNA degradation associated
chr10_+_72197977 Show fit	37.02	ENSRNOT00000003886	Myo19 NCBI RGD Ensembl Show fit	myosin XIX
chr8_+_22625874 Show fit	36.71	ENSRNOT00000012269	Timm29 NCBI RGD Ensembl Show fit	translocase of inner mitochondrial membrane 29
chr2_-_183582553 Show fit	36.67	ENSRNOT00000014236	Arfip1 NCBI RGD Ensembl Show fit	ADP-ribosylation factor interacting protein 1
chr2_+_4195917 Show fit	36.58	ENSRNOT00000093303	RGD1560883 NCBI RGD Ensembl Show fit	similar to KIAA0825 protein
chr4_+_56625561 Show fit	36.28	ENSRNOT00000008356 ENSRNOT00000090808 ENSRNOT00000008972	Calu NCBI RGD Ensembl Show fit	calumenin
chr1_+_247110216 Show fit	35.66	ENSRNOT00000016000	Cdc37l1 NCBI RGD Ensembl Show fit	cell division cycle 37-like 1
chr3_-_92242318 Show fit	35.61	ENSRNOT00000007018	Trim44 NCBI RGD Ensembl Show fit	tripartite motif-containing 44
chr7_-_117140168 Show fit	35.55	ENSRNOT00000056481 ENSRNOT00000013353	Puf60 NCBI RGD Ensembl Show fit	poly-U binding splicing factor 60
chr1_+_189665976 Show fit	35.49	ENSRNOT00000033673	Lyrm1 NCBI RGD Ensembl Show fit	LYR motif containing 1
chr8_+_113603533 Show fit	35.37	ENSRNOT00000017280	Mrpl3 NCBI RGD Ensembl Show fit	mitochondrial ribosomal protein L3
chr4_+_155709613 Show fit	35.21	ENSRNOT00000013272	Necap1 NCBI RGD Ensembl Show fit	NECAP endocytosis associated 1
chr5_-_127523089 Show fit	35.19	ENSRNOT00000016954	Cpt2 NCBI RGD Ensembl Show fit	carnitine palmitoyltransferase 2
chr7_-_95310005 Show fit	35.08	ENSRNOT00000005815	Mrpl13 NCBI RGD Ensembl Show fit	mitochondrial ribosomal protein L13
chr4_-_157486844 Show fit	34.80	ENSRNOT00000038281 ENSRNOT00000022874	Cops7a NCBI RGD Ensembl Show fit	COP9 signalosome subunit 7A
chr3_-_60105212 Show fit	34.68	ENSRNOT00000086329 ENSRNOT00000025158	Gpr155 NCBI RGD Ensembl Show fit	G protein-coupled receptor 155
chr5_+_104941066 Show fit	34.67	ENSRNOT00000009225	Rraga NCBI RGD Ensembl Show fit	Ras-related GTP binding A
chr5_-_135397591 Show fit	34.65	ENSRNOT00000050434	Tmem69 NCBI RGD Ensembl Show fit	transmembrane protein 69
chr8_-_50199978 Show fit	34.45	ENSRNOT00000023459	Rnf214 NCBI RGD Ensembl Show fit	ring finger protein 214
chr11_-_45510961 Show fit	34.44	ENSRNOT00000002238	Tomm70 NCBI RGD Ensembl Show fit	translocase of outer mitochondrial membrane 70
chr12_+_2170630 Show fit	34.18	ENSRNOT00000071928	Pet100 NCBI RGD Ensembl Show fit	PET100 homolog
chr2_+_218951141 Show fit	34.16	ENSRNOT00000091001	Extl2 NCBI RGD Ensembl Show fit	exostosin-like glycosyltransferase 2
chr2_+_84678948 Show fit	34.14	ENSRNOT00000046325	Fam173b NCBI RGD Ensembl Show fit	family with sequence similarity 173, member B
chr8_+_117246376 Show fit	34.10	ENSRNOT00000074493	Ccdc71 NCBI RGD Ensembl Show fit	coiled-coil domain containing 71
chr5_-_57267002 Show fit	33.85	ENSRNOT00000011455	Bag1 NCBI RGD Ensembl Show fit	Bcl2 associated athanogene 1
chr6_+_2969333 Show fit	33.79	ENSRNOT00000047356	Morn2 NCBI RGD Ensembl Show fit	MORN repeat containing 2
chr13_-_88536728 Show fit	33.76	ENSRNOT00000003950	Uhmk1 NCBI RGD Ensembl Show fit	U2AF homology motif kinase 1
chr10_-_40201992 Show fit	33.61	ENSRNOT00000075311	Lyrm7 NCBI RGD Ensembl Show fit	LYR motif containing 7
chr1_+_226947105 Show fit	33.61	ENSRNOT00000028373	Prpf19 NCBI RGD Ensembl Show fit	pre-mRNA processing factor 19
chr3_+_61756148 Show fit	33.49	ENSRNOT00000002134	Mtx2 NCBI RGD Ensembl Show fit	metaxin 2
chr1_-_222167447 Show fit	33.41	ENSRNOT00000028687	Prdx5 NCBI RGD Ensembl Show fit	peroxiredoxin 5
chr5_-_134927235 Show fit	33.23	ENSRNOT00000016751	Uqcrh NCBI RGD Ensembl Show fit	ubiquinol-cytochrome c reductase hinge protein
chr7_+_121480723 Show fit	33.16	ENSRNOT00000065304	Atf4 NCBI RGD Ensembl Show fit	activating transcription factor 4
chr1_-_72311856 Show fit	33.10	ENSRNOT00000021286	Epn1 NCBI RGD Ensembl Show fit	Epsin 1
chr13_-_109483868 Show fit	32.88	ENSRNOT00000067017 ENSRNOT00000087305	Rps6kc1 NCBI RGD Ensembl Show fit	ribosomal protein S6 kinase C1
chr3_-_161272460 Show fit	32.79	ENSRNOT00000020740	Acot8 NCBI RGD Ensembl Show fit	acyl-CoA thioesterase 8
chr18_-_60002529 Show fit	32.43	ENSRNOT00000081014 ENSRNOT00000024264 ENSRNOT00000059162	Nars NCBI RGD Ensembl Show fit	asparaginyl-tRNA synthetase
chr10_-_37209881 Show fit	32.42	ENSRNOT00000090475	Sec24a NCBI RGD Ensembl Show fit	SEC24 homolog A, COPII coat complex component
chrX_-_32355296 Show fit	32.21	ENSRNOT00000081652 ENSRNOT00000065075	Ap1s2 NCBI RGD Ensembl Show fit	adaptor-related protein complex 1, sigma 2 subunit
chr9_+_17225122 Show fit	32.19	ENSRNOT00000068747 ENSRNOT00000080816	Rsph9 NCBI RGD Ensembl Show fit	radial spoke head 9 homolog
chr8_+_62696720 Show fit	32.07	ENSRNOT00000010083	Ubl7 NCBI RGD Ensembl Show fit	ubiquitin-like 7
chr9_+_102862890 Show fit	32.04	ENSRNOT00000050494 ENSRNOT00000080129	Fam174a NCBI RGD Ensembl Show fit	family with sequence similarity 174, member A
chr14_-_104375649 Show fit	31.61	ENSRNOT00000006607	Actr2 NCBI RGD Ensembl Show fit	ARP2 actin related protein 2 homolog
chr5_+_156668712 Show fit	31.18	ENSRNOT00000067228	Ddost NCBI RGD Ensembl Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr5_+_172488708 Show fit	31.15	ENSRNOT00000019930	Morn1 NCBI RGD Ensembl Show fit	MORN repeat containing 1
chr11_-_31103520 Show fit	31.15	ENSRNOT00000030279	RGD1306954 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 1110004E09
chr3_-_22952063 Show fit	31.02	ENSRNOT00000083850	Psmb7 NCBI RGD Ensembl Show fit	proteasome subunit beta 7
chr1_-_84986581 Show fit	31.01	ENSRNOT00000025819	Psmc4 NCBI RGD Ensembl Show fit	proteasome 26S subunit, ATPase 4
chr6_+_86651196 Show fit	30.83	ENSRNOT00000034756	RGD1307621 NCBI RGD Ensembl Show fit	hypothetical LOC314168
chr8_+_55037750 Show fit	30.83	ENSRNOT00000013188	Timm8b NCBI RGD Ensembl Show fit	translocase of inner mitochondrial membrane 8 homolog B
chr1_+_170471238 Show fit	30.73	ENSRNOT00000076961 ENSRNOT00000075597 ENSRNOT00000076631 ENSRNOT00000076783	Timm10b NCBI RGD Ensembl Show fit Dnhd1 NCBI RGD Ensembl Show fit	translocase of inner mitochondrial membrane 10B dynein heavy chain domain 1
chr1_-_219259448 Show fit	30.49	ENSRNOT00000024517	Ndufv1 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase core subunit V1
chr1_+_81365138 Show fit	30.44	ENSRNOT00000026793	Cadm4 NCBI RGD Ensembl Show fit	cell adhesion molecule 4
chr3_+_113423693 Show fit	30.18	ENSRNOT00000021091	Hypk NCBI RGD Ensembl Show fit	Huntingtin interacting protein K
chr1_-_170471076 Show fit	30.18	ENSRNOT00000025159	Arfip2 NCBI RGD Ensembl Show fit	ADP-ribosylation factor interacting protein 2
chr1_+_276309927 Show fit	30.13	ENSRNOT00000067460 ENSRNOT00000066236	Vti1a NCBI RGD Ensembl Show fit	vesicle transport through interaction with t-SNAREs 1A
chr4_+_145399913 Show fit	30.10	ENSRNOT00000012177	Jagn1 NCBI RGD Ensembl Show fit	jagunal homolog 1
chr5_+_162183327 Show fit	30.10	ENSRNOT00000037875	Pramef8 NCBI RGD Ensembl Show fit	PRAME family member 8
chr8_+_112594691 Show fit	29.93	ENSRNOT00000038383 ENSRNOT00000081281	Acad11 NCBI RGD Ensembl Show fit	acyl-CoA dehydrogenase family, member 11
chr6_+_108076306 Show fit	29.66	ENSRNOT00000014913	Coq6 NCBI RGD Ensembl Show fit	coenzyme Q6 monooxygenase
chr1_-_192025350 Show fit	29.66	ENSRNOT00000071946	Ears2 NCBI RGD Ensembl Show fit	glutamyl-tRNA synthetase 2, mitochondrial
chr1_-_92069160 Show fit	29.57	ENSRNOT00000039115	Dpy19l3 NCBI RGD Ensembl Show fit	dpy-19-like 3 (C. elegans)
chr3_-_1868015 Show fit	29.56	ENSRNOT00000048945	Cacna1b NCBI RGD Ensembl Show fit	calcium voltage-gated channel subunit alpha1 B
chr9_-_44024876 Show fit	29.41	ENSRNOT00000024366	Coa5 NCBI RGD Ensembl Show fit	cytochrome C oxidase assembly factor 5
chr2_-_20919824 Show fit	29.33	ENSRNOT00000086300	Zcchc9 NCBI RGD Ensembl Show fit	zinc finger CCHC-type containing 9
chr16_-_2367069 Show fit	29.29	ENSRNOT00000079625	Pde12 NCBI RGD Ensembl Show fit	phosphodiesterase 12
chr8_-_70215719 Show fit	29.22	ENSRNOT00000015598	Rab11a NCBI RGD Ensembl Show fit	RAB11a, member RAS oncogene family
chr1_+_174655939 Show fit	29.04	ENSRNOT00000014002	Ipo7 NCBI RGD Ensembl Show fit	importin 7
chr11_-_86328469 Show fit	29.03	ENSRNOT00000071493	Ufd1l NCBI RGD Ensembl Show fit	ubiquitin fusion degradation 1 like (yeast)
chr8_+_117455262 Show fit	29.02	ENSRNOT00000027520	Slc25a20 NCBI RGD Ensembl Show fit	solute carrier family 25 member 20
chrX_+_1787266 Show fit	28.95	ENSRNOT00000011183	Ndufb11 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit B11
chr2_-_219842986 Show fit	28.94	ENSRNOT00000055735	Agl NCBI RGD Ensembl Show fit	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr4_-_157266018 Show fit	28.91	ENSRNOT00000019570	LOC100911713 NCBI RGD Ensembl Show fit	protein C10-like
chr14_-_42520020 Show fit	28.90	ENSRNOT00000065550	Slc30a9 NCBI RGD Ensembl Show fit	solute carrier family 30 member 9
chr8_-_114853103 Show fit	28.82	ENSRNOT00000074595	Glyctk NCBI RGD Ensembl Show fit	glycerate kinase
chr11_-_24294179 Show fit	28.79	ENSRNOT00000002116	Atp5j NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr3_+_121660110 Show fit	28.70	ENSRNOT00000024942	Chchd5 NCBI RGD Ensembl Show fit	coiled-coil-helix-coiled-coil-helix domain containing 5
chr8_-_36410612 Show fit	28.60	ENSRNOT00000091308	Foxred1 NCBI RGD Ensembl Show fit	FAD-dependent oxidoreductase domain containing 1
chr1_-_264756546 Show fit	28.48	ENSRNOT00000020020	Mrpl43 NCBI RGD Ensembl Show fit	mitochondrial ribosomal protein L43
chr10_+_95706685 Show fit	28.46	ENSRNOT00000004283	Psmd12 NCBI RGD Ensembl Show fit	proteasome 26S subunit, non-ATPase 12
chr8_+_115179893 Show fit	28.37	ENSRNOT00000017469	Rrp9 NCBI RGD Ensembl Show fit	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr8_+_61080103 Show fit	28.29	ENSRNOT00000022976	Hmg20a NCBI RGD Ensembl Show fit	high mobility group 20A
chr8_-_77992621 Show fit	28.22	ENSRNOT00000085843	Myzap NCBI RGD Ensembl Show fit	myocardial zonula adherens protein
chr6_-_26241337 Show fit	28.15	ENSRNOT00000006525	Slc4a1ap NCBI RGD Ensembl Show fit	solute carrier family 4 member 1 adaptor protein
chr13_-_45127815 Show fit	28.14	ENSRNOT00000005127	Dars NCBI RGD Ensembl Show fit	aspartyl-tRNA synthetase
chr5_-_136541795 Show fit	28.08	ENSRNOT00000026336	Dmap1 NCBI RGD Ensembl Show fit	DNA methyltransferase 1-associated protein 1
chr2_-_188471988 Show fit	28.08	ENSRNOT00000027785	Hcn3 NCBI RGD Ensembl Show fit	hyperpolarization-activated cyclic nucleotide-gated potassium channel 3
chr1_-_226572349 Show fit	28.01	ENSRNOT00000028028	Sdhaf2 NCBI RGD Ensembl Show fit	succinate dehydrogenase complex assembly factor 2
chr7_-_70355619 Show fit	27.89	ENSRNOT00000031272	Tspan31 NCBI RGD Ensembl Show fit	tetraspanin 31
chr16_-_20873344 Show fit	27.79	ENSRNOT00000027381	Cope NCBI RGD Ensembl Show fit	coatomer protein complex, subunit epsilon
chr8_-_22625959 Show fit	27.74	ENSRNOT00000012138	Yipf2 NCBI RGD Ensembl Show fit	Yip1 domain family, member 2
chr1_+_255479261 Show fit	27.71	ENSRNOT00000079808	Tnks2 NCBI RGD Ensembl Show fit	tankyrase 2
chr9_+_43259709 Show fit	27.68	ENSRNOT00000022487	Cox5b NCBI RGD Ensembl Show fit	cytochrome c oxidase subunit 5B
chr1_+_84361736 Show fit	27.62	ENSRNOT00000077968	RGD1307554 NCBI RGD Ensembl Show fit	similar to CG16812-PA
chr12_-_48663143 Show fit	27.55	ENSRNOT00000082809	Ficd NCBI RGD Ensembl Show fit	FIC domain containing
chr1_+_228142778 Show fit	27.50	ENSRNOT00000028517	Mrpl16 NCBI RGD Ensembl Show fit	mitochondrial ribosomal protein L16
chr2_+_98252925 Show fit	27.49	ENSRNOT00000011579	Pex2 NCBI RGD Ensembl Show fit	peroxisomal biogenesis factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Etv3_Erf_Fev_Elk4_Elk1_Elk3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
42.3	169.3	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
37.9	113.7	GO:0018282	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
25.1	75.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
22.0	131.8	GO:0006449	regulation of translational termination(GO:0006449)
21.2	106.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
19.5	58.5	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
16.6	33.2	GO:1990737	response to manganese-induced endoplasmic reticulum stress(GO:1990737)
16.5	82.6	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
15.2	76.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
15.2	45.5	GO:0010796	regulation of multivesicular body size(GO:0010796)
15.2	45.5	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
14.9	164.4	GO:0032933	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
14.5	43.5	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
13.9	41.7	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
13.4	40.2	GO:0044565	dendritic cell proliferation(GO:0044565)
13.2	39.7	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
13.0	77.8	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
12.8	38.3	GO:0015938	coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) fatty-acyl-CoA catabolic process(GO:0036115)
12.1	48.6	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
12.1	72.7	GO:1903215	negative regulation of mRNA modification(GO:0090367) negative regulation of protein targeting to mitochondrion(GO:1903215)
11.8	58.9	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
11.2	44.9	GO:1903895	negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
11.1	33.4	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
10.8	32.4	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
10.4	83.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
9.4	18.7	GO:0014736	negative regulation of muscle atrophy(GO:0014736)
9.1	27.4	GO:1905244	negative regulation of long term synaptic depression(GO:1900453) regulation of intracellular transport of viral material(GO:1901252) regulation of modification of synaptic structure(GO:1905244)
9.0	116.4	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617)
8.5	34.0	GO:1904431	positive regulation of t-circle formation(GO:1904431)
8.3	25.0	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
8.0	24.0	GO:0042489	negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
7.9	79.2	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
7.9	23.6	GO:0021678	third ventricle development(GO:0021678)
7.8	141.2	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
7.4	96.6	GO:0017004	cytochrome complex assembly(GO:0017004)
7.4	29.7	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
7.4	66.5	GO:0010668	ectodermal cell differentiation(GO:0010668)
7.4	29.6	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
7.4	58.9	GO:0051182	coenzyme transport(GO:0051182)
7.3	29.0	GO:0015879	carnitine transport(GO:0015879)
7.1	42.5	GO:0006102	isocitrate metabolic process(GO:0006102)
7.0	35.2	GO:0034227	tRNA thio-modification(GO:0034227)
6.9	34.7	GO:0045919	positive regulation of cytolysis(GO:0045919)
6.9	27.6	GO:0038158	granulocyte colony-stimulating factor signaling pathway(GO:0038158)
6.8	33.9	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
6.7	40.4	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
6.4	19.2	GO:0006533	fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
6.4	19.2	GO:0018343	protein farnesylation(GO:0018343)
6.4	114.5	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
6.3	18.8	GO:0060816	random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
6.2	24.9	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
6.1	18.2	GO:0019086	late viral transcription(GO:0019086)
6.1	66.7	GO:0000338	protein deneddylation(GO:0000338)
6.0	42.3	GO:0098904	regulation of AV node cell action potential(GO:0098904)
6.0	30.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
6.0	41.8	GO:0019348	dolichol metabolic process(GO:0019348)
5.8	81.8	GO:0071420	cellular response to histamine(GO:0071420)
5.7	17.2	GO:0034628	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
5.5	22.2	GO:0051031	tRNA transport(GO:0051031)
5.5	21.9	GO:0090234	regulation of kinetochore assembly(GO:0090234)
5.5	16.4	GO:0030576	Cajal body organization(GO:0030576)
5.4	16.3	GO:2000845	positive regulation of testosterone secretion(GO:2000845)
5.4	123.3	GO:0045116	protein neddylation(GO:0045116)
5.3	16.0	GO:0044375	regulation of peroxisome size(GO:0044375)
5.2	15.7	GO:0021699	cerebellar cortex maturation(GO:0021699)
5.1	40.8	GO:0016559	peroxisome fission(GO:0016559)
5.1	5.1	GO:0071569	protein ufmylation(GO:0071569)
4.9	14.6	GO:0044313	protein K6-linked deubiquitination(GO:0044313)
4.9	19.4	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
4.8	43.5	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
4.8	28.6	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
4.7	47.4	GO:0001302	replicative cell aging(GO:0001302)
4.7	9.5	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
4.7	9.4	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
4.7	174.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
4.7	18.7	GO:1903677	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
4.6	13.9	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
4.6	55.6	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
4.6	23.1	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
4.6	18.3	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
4.5	13.6	GO:0019249	lactate biosynthetic process(GO:0019249) amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
4.5	76.9	GO:0006662	glycerol ether metabolic process(GO:0006662)
4.3	39.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
4.3	51.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
4.2	12.7	GO:2000313	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
4.2	42.0	GO:0018095	protein polyglutamylation(GO:0018095)
4.2	12.6	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
4.2	12.6	GO:0090149	mitochondrial membrane fission(GO:0090149)
4.1	20.7	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
4.1	12.4	GO:0019677	NADP catabolic process(GO:0006742) NAD catabolic process(GO:0019677)
4.1	41.1	GO:0035721	intraciliary retrograde transport(GO:0035721)
4.1	20.5	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
4.1	32.4	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
4.0	4.0	GO:1903094	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
4.0	11.9	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
3.9	7.9	GO:0010847	regulation of chromatin assembly(GO:0010847)
3.9	50.9	GO:0090169	regulation of spindle assembly(GO:0090169) regulation of mitotic spindle assembly(GO:1901673)
3.9	15.6	GO:0002084	protein depalmitoylation(GO:0002084)
3.8	19.2	GO:0075525	viral translational termination-reinitiation(GO:0075525)
3.8	23.0	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
3.8	45.8	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
3.7	33.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
3.7	121.4	GO:0042773	ATP synthesis coupled electron transport(GO:0042773)
3.6	10.8	GO:0043928	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
3.6	3.6	GO:0006598	polyamine catabolic process(GO:0006598)
3.5	6.9	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
3.5	20.7	GO:1902969	mitotic DNA replication(GO:1902969)
3.4	131.0	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
3.4	6.8	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160)
3.4	17.0	GO:0035627	ceramide transport(GO:0035627)
3.4	10.2	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
3.4	60.4	GO:0050667	homocysteine metabolic process(GO:0050667)
3.3	89.9	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
3.2	38.8	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
3.2	9.5	GO:0044571	[2Fe-2S] cluster assembly(GO:0044571)
3.1	9.4	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
3.1	6.3	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
3.1	12.5	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
3.1	9.3	GO:1903445	protein transport from ciliary membrane to plasma membrane(GO:1903445)
3.1	12.3	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
3.0	23.9	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
3.0	91.9	GO:0006829	zinc II ion transport(GO:0006829)
2.9	8.8	GO:1904009	cellular response to monosodium glutamate(GO:1904009)
2.9	14.6	GO:0070125	mitochondrial translational elongation(GO:0070125)
2.9	57.7	GO:0006625	protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
2.8	14.2	GO:0033523	histone H2B ubiquitination(GO:0033523)
2.8	59.3	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
2.8	45.2	GO:0071044	histone mRNA catabolic process(GO:0071044)
2.8	5.6	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
2.8	47.4	GO:0043248	proteasome assembly(GO:0043248)
2.8	5.5	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
2.7	27.3	GO:0007220	Notch receptor processing(GO:0007220)
2.7	8.2	GO:2000437	regulation of monocyte extravasation(GO:2000437)
2.7	29.9	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
2.7	32.6	GO:0072718	response to cisplatin(GO:0072718)
2.7	5.4	GO:0046066	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
2.7	8.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
2.7	61.3	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
2.7	66.4	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)
2.6	18.3	GO:0098885	modification of postsynaptic actin cytoskeleton(GO:0098885)
2.6	26.1	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
2.6	38.9	GO:0060294	cilium movement involved in cell motility(GO:0060294)
2.6	10.3	GO:0001692	histamine metabolic process(GO:0001692)
2.6	25.8	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
2.6	7.7	GO:0035928	rRNA import into mitochondrion(GO:0035928)
2.6	30.8	GO:0034498	early endosome to Golgi transport(GO:0034498)
2.6	10.3	GO:0032439	endosome localization(GO:0032439)
2.5	10.1	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
2.5	22.5	GO:0015825	L-serine transport(GO:0015825)
2.5	22.2	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
2.4	198.4	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
2.4	92.0	GO:0032543	mitochondrial translation(GO:0032543)
2.4	9.4	GO:1902774	late endosome to lysosome transport(GO:1902774)
2.3	34.6	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
2.3	16.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
2.3	18.3	GO:0070861	regulation of protein exit from endoplasmic reticulum(GO:0070861)
2.3	25.1	GO:0042407	cristae formation(GO:0042407)
2.3	6.8	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
2.3	36.3	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
2.2	6.7	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
2.2	8.9	GO:0006011	UDP-glucose metabolic process(GO:0006011)
2.2	6.6	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
2.2	6.5	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
2.2	32.4	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
2.1	30.1	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
2.1	8.5	GO:0061534	forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
2.1	36.0	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
2.1	41.7	GO:0022900	electron transport chain(GO:0022900)
2.1	2.1	GO:1904638	response to resveratrol(GO:1904638)
2.1	14.5	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
2.1	14.4	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
2.0	14.3	GO:0043654	recognition of apoptotic cell(GO:0043654)
2.0	12.1	GO:0097491	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
2.0	8.1	GO:1903333	negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
2.0	12.0	GO:0042713	sperm ejaculation(GO:0042713) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
2.0	23.8	GO:0071806	protein transmembrane transport(GO:0071806)
2.0	7.9	GO:0010999	regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
2.0	5.9	GO:1990790	response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
2.0	5.9	GO:0001546	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
2.0	23.6	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
1.9	30.9	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
1.9	15.3	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.9	9.6	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
1.9	85.8	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
1.9	28.3	GO:0043968	histone H2A acetylation(GO:0043968)
1.9	13.1	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
1.9	14.8	GO:0070294	renal sodium ion absorption(GO:0070294)
1.8	9.2	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
1.8	32.9	GO:0006020	inositol metabolic process(GO:0006020)
1.8	40.0	GO:0046037	GMP metabolic process(GO:0046037)
1.8	3.6	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
1.8	17.7	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
1.7	5.2	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
1.7	85.6	GO:0021762	substantia nigra development(GO:0021762)
1.7	5.1	GO:0009249	protein lipoylation(GO:0009249)
1.6	9.9	GO:0015074	DNA integration(GO:0015074)
1.6	9.8	GO:0036438	maintenance of lens transparency(GO:0036438)
1.6	8.2	GO:0006287	base-excision repair, gap-filling(GO:0006287)
1.6	16.1	GO:0090153	regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
1.6	4.8	GO:0010968	regulation of microtubule nucleation(GO:0010968)
1.6	9.5	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.6	12.6	GO:0048278	vesicle docking(GO:0048278)
1.6	37.2	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
1.5	7.7	GO:0032707	negative regulation of interleukin-23 production(GO:0032707)
1.5	51.8	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
1.5	5.9	GO:1990839	response to endothelin(GO:1990839) cellular response to endothelin(GO:1990859)
1.5	16.1	GO:0000722	telomere maintenance via recombination(GO:0000722)
1.4	15.7	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
1.4	1.4	GO:0046070	dGTP metabolic process(GO:0046070)
1.4	24.1	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
1.4	4.2	GO:0034472	snRNA 3'-end processing(GO:0034472)
1.4	2.8	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
1.4	29.9	GO:0005980	glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
1.4	20.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.3	9.4	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
1.3	14.7	GO:1904424	regulation of GTP binding(GO:1904424)
1.3	5.2	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
1.3	3.9	GO:0007228	signal transduction downstream of smoothened(GO:0007227) positive regulation of hh target transcription factor activity(GO:0007228)
1.3	2.6	GO:2000619	negative regulation of histone H4-K16 acetylation(GO:2000619)
1.3	7.6	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
1.2	8.7	GO:0060526	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
1.2	5.0	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
1.2	38.9	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
1.2	4.8	GO:0031642	negative regulation of myelination(GO:0031642)
1.2	2.4	GO:0080120	CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
1.2	10.8	GO:0007000	nucleolus organization(GO:0007000)
1.2	158.7	GO:0006626	protein targeting to mitochondrion(GO:0006626)
1.2	16.5	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.2	36.2	GO:0007029	endoplasmic reticulum organization(GO:0007029)
1.2	3.5	GO:0072709	cellular response to sorbitol(GO:0072709)
1.2	2.3	GO:0032258	CVT pathway(GO:0032258)
1.1	33.8	GO:0046825	regulation of protein export from nucleus(GO:0046825)
1.1	3.4	GO:0006408	snRNA export from nucleus(GO:0006408)
1.1	6.7	GO:1901621	response to clozapine(GO:0097338) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
1.1	10.8	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
1.1	7.6	GO:0050915	sensory perception of sour taste(GO:0050915)
1.1	4.2	GO:0090625	mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
1.1	54.1	GO:0051865	protein autoubiquitination(GO:0051865)
1.1	10.5	GO:0006657	CDP-choline pathway(GO:0006657)
1.0	9.3	GO:2000650	negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
1.0	3.1	GO:0052564	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
1.0	10.2	GO:0006183	GTP biosynthetic process(GO:0006183) guanosine-containing compound biosynthetic process(GO:1901070)
1.0	13.2	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
1.0	18.0	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
1.0	12.4	GO:0046325	negative regulation of glucose import(GO:0046325)
0.9	20.7	GO:0035641	locomotory exploration behavior(GO:0035641)
0.9	42.8	GO:0060976	coronary vasculature development(GO:0060976)
0.9	46.8	GO:0007041	lysosomal transport(GO:0007041)
0.9	23.8	GO:0001956	positive regulation of neurotransmitter secretion(GO:0001956)
0.9	6.3	GO:0048102	autophagic cell death(GO:0048102)
0.9	2.6	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.9	8.6	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.8	32.2	GO:0036465	synaptic vesicle recycling(GO:0036465)
0.8	3.3	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.8	4.9	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.8	8.2	GO:0008215	spermine metabolic process(GO:0008215)
0.8	4.9	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.8	25.6	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039)
0.8	16.7	GO:0006301	postreplication repair(GO:0006301)
0.8	1.6	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.8	7.7	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.8	7.7	GO:0051601	exocyst localization(GO:0051601)
0.8	6.9	GO:0030575	nuclear body organization(GO:0030575)
0.8	15.2	GO:0006458	'de novo' protein folding(GO:0006458)
0.8	1.5	GO:0030242	pexophagy(GO:0030242)
0.7	4.5	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.7	2.2	GO:0035552	oxidative single-stranded DNA demethylation(GO:0035552)
0.7	5.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.7	5.1	GO:0006465	signal peptide processing(GO:0006465)
0.7	2.2	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) mammary gland specification(GO:0060594)
0.7	5.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.7	1.4	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.7	9.9	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.7	35.2	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.7	4.9	GO:0061462	protein localization to lysosome(GO:0061462)
0.7	9.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.7	8.3	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.7	13.8	GO:0006611	protein export from nucleus(GO:0006611)
0.7	12.9	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.7	7.5	GO:0007097	nuclear migration(GO:0007097)
0.7	20.1	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.7	26.1	GO:0003009	skeletal muscle contraction(GO:0003009) synaptic transmission, cholinergic(GO:0007271)
0.7	5.3	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.7	11.2	GO:0000266	mitochondrial fission(GO:0000266)
0.7	41.4	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.6	6.5	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.6	11.6	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.6	3.8	GO:0021764	amygdala development(GO:0021764)
0.6	28.0	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.6	3.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.6	0.6	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.6	20.8	GO:0006817	phosphate ion transport(GO:0006817)
0.6	12.7	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.6	7.8	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.6	2.4	GO:0061709	reticulophagy(GO:0061709)
0.6	0.6	GO:0071033	nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.6	5.2	GO:0070995	NADPH oxidation(GO:0070995)
0.6	4.6	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.6	13.9	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) calcineurin-NFAT signaling cascade(GO:0033173)
0.6	4.0	GO:0021860	pyramidal neuron development(GO:0021860)
0.6	1.7	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.6	26.2	GO:0044042	glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.5	6.0	GO:0031167	rRNA methylation(GO:0031167)
0.5	7.6	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.5	8.5	GO:0001919	regulation of receptor recycling(GO:0001919)
0.5	15.8	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.5	5.1	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.5	20.1	GO:0046324	regulation of glucose import(GO:0046324)
0.5	8.0	GO:0072583	clathrin-mediated endocytosis(GO:0072583)
0.5	2.0	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.5	3.5	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.5	6.4	GO:0016180	snRNA processing(GO:0016180)
0.5	11.2	GO:0030488	tRNA methylation(GO:0030488)
0.5	2.4	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.5	1.9	GO:0070173	regulation of enamel mineralization(GO:0070173)
0.5	1.4	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226) positive regulation of cell adhesion molecule production(GO:0060355)
0.4	112.0	GO:0010498	proteasomal protein catabolic process(GO:0010498)
0.4	1.8	GO:0072014	proximal tubule development(GO:0072014)
0.4	5.8	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.4	33.1	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.4	27.4	GO:0035308	negative regulation of protein dephosphorylation(GO:0035308)
0.4	9.1	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.4	3.4	GO:0003351	epithelial cilium movement(GO:0003351)
0.4	20.7	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.4	2.1	GO:0090494	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.4	19.0	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.4	0.8	GO:0008089	anterograde axonal transport(GO:0008089)
0.4	3.6	GO:0015747	urate transport(GO:0015747)
0.4	10.9	GO:0018196	peptidyl-asparagine modification(GO:0018196)
0.4	6.8	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.4	7.5	GO:0097480	synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480)
0.4	3.0	GO:0070197	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.4	0.7	GO:0070459	prolactin secretion(GO:0070459)
0.4	12.4	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.4	2.2	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.4	14.1	GO:0035094	response to nicotine(GO:0035094)
0.4	4.9	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
0.4	4.9	GO:0070932	histone H3 deacetylation(GO:0070932)
0.3	2.4	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3	1.3	GO:0032264	IMP salvage(GO:0032264)
0.3	1.6	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3	2.6	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.3	7.6	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.3	3.4	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.3	2.1	GO:0035878	nail development(GO:0035878)
0.3	1.5	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.3	0.9	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.3	2.1	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.3	5.8	GO:0048011	neurotrophin TRK receptor signaling pathway(GO:0048011)
0.3	0.6	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.3	6.2	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.3	2.3	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.3	0.8	GO:0015746	citrate transport(GO:0015746)
0.3	13.8	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.2	0.5	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.2	16.6	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.2	2.4	GO:0021554	optic nerve development(GO:0021554)
0.2	3.9	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.2	0.7	GO:0033092	positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.2	3.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.2	8.5	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.2	56.1	GO:0006887	exocytosis(GO:0006887)
0.2	21.6	GO:0007219	Notch signaling pathway(GO:0007219)
0.2	0.6	GO:2000010	positive regulation of protein localization to cell surface(GO:2000010)
0.2	1.2	GO:0032482	Rab protein signal transduction(GO:0032482)
0.2	8.8	GO:0045732	positive regulation of protein catabolic process(GO:0045732)
0.2	2.3	GO:0007032	endosome organization(GO:0007032)
0.2	2.0	GO:0016239	positive regulation of macroautophagy(GO:0016239)
0.2	25.3	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2	6.4	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.2	2.1	GO:0010669	epithelial structure maintenance(GO:0010669)
0.2	6.4	GO:0000209	protein polyubiquitination(GO:0000209)
0.2	5.7	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.2	19.9	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.2	2.1	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2	1.2	GO:0032418	lysosome localization(GO:0032418)
0.2	0.6	GO:0015889	cobalamin transport(GO:0015889)
0.2	4.9	GO:0035987	endodermal cell differentiation(GO:0035987)
0.2	3.4	GO:0061512	protein localization to cilium(GO:0061512)
0.1	8.9	GO:0042633	molting cycle(GO:0042303) hair cycle(GO:0042633)
0.1	2.3	GO:0010762	regulation of fibroblast migration(GO:0010762)
0.1	11.1	GO:0006457	protein folding(GO:0006457)
0.1	2.6	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.1	0.7	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.1	3.8	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1	1.1	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	2.8	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	2.1	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.1	0.4	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1	1.4	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1	0.3	GO:0002188	translation reinitiation(GO:0002188)
0.1	1.1	GO:0010269	response to selenium ion(GO:0010269)
0.1	2.4	GO:0006505	GPI anchor metabolic process(GO:0006505)
0.1	2.8	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1	0.7	GO:0006833	water transport(GO:0006833)
0.1	6.3	GO:0006694	steroid biosynthetic process(GO:0006694)
0.1	2.3	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.1	0.3	GO:0019695	choline metabolic process(GO:0019695)
0.1	8.8	GO:0050890	cognition(GO:0050890)
0.1	0.9	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	3.2	GO:0003014	renal system process(GO:0003014)
0.0	0.5	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	1.6	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0	38.8	GO:0007608	sensory perception of smell(GO:0007608)
0.0	1.9	GO:0030307	positive regulation of cell growth(GO:0030307)
0.0	0.2	GO:0036159	inner dynein arm assembly(GO:0036159)
0.0	0.8	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.2	GO:0002042	cell migration involved in sprouting angiogenesis(GO:0002042)
0.0	0.4	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
47.5	142.6	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
44.1	176.2	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
27.7	83.2	GO:0032807	DNA ligase IV complex(GO:0032807)
19.5	78.0	GO:0000938	GARP complex(GO:0000938) EARP complex(GO:1990745)
17.9	143.0	GO:0031595	nuclear proteasome complex(GO:0031595)
14.8	59.1	GO:0032044	DSIF complex(GO:0032044)
14.2	42.5	GO:0005962	mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
13.9	41.8	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
13.6	109.0	GO:0016272	prefoldin complex(GO:0016272)
13.3	40.0	GO:1902560	GMP reductase complex(GO:1902560)
11.7	58.5	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
11.2	55.9	GO:0097361	CIA complex(GO:0097361)
11.1	33.2	GO:1990589	Lewy body core(GO:1990037) ATF4-CREB1 transcription factor complex(GO:1990589) ATF1-ATF4 transcription factor complex(GO:1990590)
10.8	32.4	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
10.5	146.9	GO:0030127	COPII vesicle coat(GO:0030127)
10.3	51.7	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
9.1	27.4	GO:0097444	spine apparatus(GO:0097444)
9.1	36.3	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
8.7	34.7	GO:0045281	respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281)
8.4	25.2	GO:0008537	proteasome activator complex(GO:0008537)
8.3	33.1	GO:0098888	extrinsic component of presynaptic membrane(GO:0098888)
7.6	45.4	GO:0097441	basilar dendrite(GO:0097441)
7.2	36.2	GO:1990130	Iml1 complex(GO:1990130)
7.2	368.2	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
7.2	100.5	GO:0017119	Golgi transport complex(GO:0017119)
7.2	42.9	GO:0070765	gamma-secretase complex(GO:0070765)
6.9	20.6	GO:0033557	Slx1-Slx4 complex(GO:0033557)
6.8	88.6	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
6.6	39.7	GO:0089701	U2AF(GO:0089701)
6.6	46.3	GO:0030991	intraciliary transport particle A(GO:0030991)
6.6	131.6	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
6.6	46.1	GO:0070449	elongin complex(GO:0070449)
6.2	43.3	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
6.1	61.5	GO:0071439	clathrin complex(GO:0071439)
5.7	68.9	GO:0030008	TRAPP complex(GO:0030008)
5.7	34.1	GO:0030478	actin cap(GO:0030478)
5.6	28.1	GO:0044316	cone cell pedicle(GO:0044316)
5.6	44.8	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
5.6	83.4	GO:0005838	proteasome regulatory particle(GO:0005838)
5.5	32.8	GO:0070847	core mediator complex(GO:0070847)
5.4	10.8	GO:0055087	Ski complex(GO:0055087)
5.3	78.9	GO:0034709	methylosome(GO:0034709)
5.2	151.1	GO:0000421	autophagosome membrane(GO:0000421)
5.2	46.7	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
5.1	15.2	GO:0000814	ESCRT II complex(GO:0000814)
5.0	15.1	GO:0033596	TSC1-TSC2 complex(GO:0033596)
4.6	63.7	GO:0005832	chaperonin-containing T-complex(GO:0005832)
4.4	13.3	GO:0070522	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
4.4	57.5	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
4.4	69.8	GO:0030126	COPI vesicle coat(GO:0030126)
4.2	12.6	GO:0098837	postsynaptic recycling endosome(GO:0098837)
4.2	92.0	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
4.0	12.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
4.0	27.7	GO:0061617	MICOS complex(GO:0061617)
3.9	232.4	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
3.9	46.9	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
3.8	30.6	GO:0031931	TORC1 complex(GO:0031931)
3.8	41.7	GO:0072546	ER membrane protein complex(GO:0072546)
3.8	30.1	GO:0000815	ESCRT III complex(GO:0000815)
3.7	29.5	GO:0031428	box C/D snoRNP complex(GO:0031428)
3.6	10.9	GO:0031372	UBC13-MMS2 complex(GO:0031372)
3.6	32.4	GO:0030897	HOPS complex(GO:0030897)
3.6	81.8	GO:1902711	GABA-A receptor complex(GO:1902711)
3.4	51.1	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
3.4	80.9	GO:0005839	proteasome core complex(GO:0005839)
3.4	6.7	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
3.3	42.8	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
3.2	29.2	GO:0005828	kinetochore microtubule(GO:0005828)
3.2	19.4	GO:0000125	PCAF complex(GO:0000125)
3.2	32.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
3.2	16.1	GO:0035061	interchromatin granule(GO:0035061)
3.2	25.3	GO:0005964	phosphorylase kinase complex(GO:0005964)
3.1	12.6	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
3.1	12.4	GO:0034657	GID complex(GO:0034657)
3.1	21.4	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
3.1	18.3	GO:0099571	postsynaptic actin cytoskeleton(GO:0098871) postsynaptic cytoskeleton(GO:0099571)
3.0	33.2	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750)
2.9	11.5	GO:0070876	SOSS complex(GO:0070876)
2.9	5.7	GO:0000322	storage vacuole(GO:0000322)
2.7	101.2	GO:0008180	COP9 signalosome(GO:0008180)
2.6	18.3	GO:0000137	Golgi cis cisterna(GO:0000137)
2.6	33.7	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
2.5	20.3	GO:0097443	sorting endosome(GO:0097443)
2.5	17.7	GO:0071986	Ragulator complex(GO:0071986)
2.4	4.8	GO:0097413	Lewy body(GO:0097413)
2.3	41.9	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
2.3	13.9	GO:0005955	calcineurin complex(GO:0005955)
2.1	8.6	GO:0032021	NELF complex(GO:0032021)
2.1	12.8	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
2.1	26.9	GO:0005675	holo TFIIH complex(GO:0005675)
2.1	45.3	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
2.0	28.5	GO:0030122	AP-2 adaptor complex(GO:0030122)
2.0	16.2	GO:0005869	dynactin complex(GO:0005869)
2.0	10.0	GO:0070069	cytochrome complex(GO:0070069)
2.0	31.5	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
1.9	5.8	GO:0030690	Noc1p-Noc2p complex(GO:0030690)
1.9	9.4	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
1.9	37.2	GO:0005680	anaphase-promoting complex(GO:0005680)
1.8	9.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
1.8	9.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
1.8	43.0	GO:0005868	cytoplasmic dynein complex(GO:0005868)
1.8	8.9	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
1.8	8.8	GO:0044327	dendritic spine head(GO:0044327)
1.8	28.1	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
1.6	16.5	GO:0008290	F-actin capping protein complex(GO:0008290)
1.6	8.2	GO:0030915	Smc5-Smc6 complex(GO:0030915)
1.6	6.5	GO:0005956	protein kinase CK2 complex(GO:0005956)
1.6	43.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
1.6	82.1	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.6	11.0	GO:0048500	signal recognition particle(GO:0048500)
1.5	16.7	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
1.5	92.6	GO:0005758	mitochondrial intermembrane space(GO:0005758)
1.5	27.9	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
1.5	10.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
1.5	59.9	GO:0005801	cis-Golgi network(GO:0005801)
1.4	28.0	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
1.4	30.4	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
1.3	14.8	GO:0042405	nuclear inclusion body(GO:0042405)
1.3	11.9	GO:0030877	beta-catenin destruction complex(GO:0030877)
1.3	31.7	GO:0000145	exocyst(GO:0000145)
1.3	736.1	GO:0044429	mitochondrial part(GO:0044429)
1.2	15.0	GO:0032797	SMN complex(GO:0032797)
1.2	5.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
1.2	13.2	GO:0016600	flotillin complex(GO:0016600)
1.2	13.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
1.2	57.0	GO:0010494	cytoplasmic stress granule(GO:0010494)
1.1	11.5	GO:0042587	glycogen granule(GO:0042587)
1.1	2.1	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
1.1	26.4	GO:0000502	proteasome complex(GO:0000502)
1.0	45.1	GO:0030173	integral component of Golgi membrane(GO:0030173)
1.0	22.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
1.0	16.2	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.9	5.7	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.9	14.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.9	6.6	GO:0001739	sex chromatin(GO:0001739)
0.9	5.5	GO:0032437	cuticular plate(GO:0032437)
0.9	7.0	GO:1990023	mitotic spindle midzone(GO:1990023)
0.9	19.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.9	39.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.9	2.6	GO:0097255	R2TP complex(GO:0097255)
0.9	5.1	GO:0005787	signal peptidase complex(GO:0005787)
0.8	5.8	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.8	12.4	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.8	58.0	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.8	4.9	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.8	2.4	GO:0033648	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.8	8.5	GO:0098839	postsynaptic density membrane(GO:0098839)
0.8	8.4	GO:0043202	lysosomal lumen(GO:0043202)
0.7	7.5	GO:0035102	PRC1 complex(GO:0035102)
0.7	6.7	GO:0032059	bleb(GO:0032059)
0.7	6.8	GO:0034464	BBSome(GO:0034464)
0.6	27.2	GO:0005637	nuclear inner membrane(GO:0005637)
0.6	33.5	GO:0016234	inclusion body(GO:0016234)
0.6	54.5	GO:0031227	intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.6	19.0	GO:0030673	axolemma(GO:0030673)
0.6	5.0	GO:0071141	SMAD protein complex(GO:0071141)
0.6	4.2	GO:0070578	RISC-loading complex(GO:0070578)
0.6	8.5	GO:0035253	ciliary rootlet(GO:0035253)
0.6	42.3	GO:0014704	intercalated disc(GO:0014704)
0.6	10.4	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.6	3.4	GO:0036157	outer dynein arm(GO:0036157)
0.5	8.7	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.5	12.1	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.5	21.6	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.5	8.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.5	3.0	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.5	11.7	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.4	7.5	GO:0030014	CCR4-NOT complex(GO:0030014)
0.4	31.7	GO:0045211	postsynaptic membrane(GO:0045211)
0.4	20.2	GO:0016459	myosin complex(GO:0016459)
0.4	19.2	GO:0031902	late endosome membrane(GO:0031902)
0.4	4.6	GO:0016580	Sin3 complex(GO:0016580)
0.4	7.9	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.4	1.1	GO:0036488	CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
0.4	71.4	GO:0031965	nuclear membrane(GO:0031965)
0.4	18.7	GO:0005811	lipid particle(GO:0005811)
0.3	3.8	GO:0042555	MCM complex(GO:0042555)
0.3	3.9	GO:0060091	kinocilium(GO:0060091)
0.3	3.8	GO:0044291	cell-cell contact zone(GO:0044291)
0.3	308.6	GO:0005739	mitochondrion(GO:0005739)
0.3	16.1	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.3	5.2	GO:0030904	retromer complex(GO:0030904)
0.3	1.5	GO:0035859	Seh1-associated complex(GO:0035859)
0.3	1.2	GO:0035339	SPOTS complex(GO:0035339)
0.3	2.1	GO:0042583	chromaffin granule(GO:0042583)
0.3	1.2	GO:0071797	LUBAC complex(GO:0071797)
0.3	1.2	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
0.3	66.8	GO:0014069	postsynaptic density(GO:0014069)
0.3	3.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.3	20.1	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3	9.1	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.2	228.4	GO:0005783	endoplasmic reticulum(GO:0005783)
0.2	22.1	GO:0008021	synaptic vesicle(GO:0008021)
0.2	13.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.2	19.0	GO:0030018	Z disc(GO:0030018)
0.2	0.7	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.2	14.5	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2	3.4	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.2	11.2	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.2	27.3	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.2	3.9	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.2	1.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.2	3.0	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.2	3.6	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2	0.9	GO:0031933	telomeric heterochromatin(GO:0031933)
0.2	13.2	GO:0016363	nuclear matrix(GO:0016363)
0.2	17.6	GO:0005802	trans-Golgi network(GO:0005802)
0.2	0.8	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.2	0.3	GO:0071203	WASH complex(GO:0071203)
0.2	1.6	GO:0032300	mismatch repair complex(GO:0032300)
0.2	3.5	GO:0060170	ciliary membrane(GO:0060170)
0.1	0.7	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	28.3	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1	4.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	0.3	GO:0061574	ASAP complex(GO:0061574)
0.1	15.2	GO:0044431	Golgi apparatus part(GO:0044431)
0.1	397.9	GO:0016021	integral component of membrane(GO:0016021)
0.0	1.5	GO:1902554	serine/threonine protein kinase complex(GO:1902554)
0.0	1.4	GO:0015030	Cajal body(GO:0015030)
0.0	2.1	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.3	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	1.0	GO:0001650	fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
25.1	75.3	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
24.1	96.5	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
23.8	71.4	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
19.5	58.5	GO:0016748	succinyltransferase activity(GO:0016748)
19.1	114.5	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
18.9	75.6	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
18.6	55.8	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
16.4	81.8	GO:0008503	benzodiazepine receptor activity(GO:0008503) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
16.2	64.7	GO:0031544	peptidyl-proline 3-dioxygenase activity(GO:0031544)
14.4	43.3	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
14.4	231.1	GO:0051787	misfolded protein binding(GO:0051787)
13.9	41.8	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
13.5	148.9	GO:0016783	sulfurtransferase activity(GO:0016783)
13.3	40.0	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
12.7	38.2	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
12.3	37.0	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
10.6	42.5	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
10.5	52.6	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
10.0	29.9	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
9.7	29.0	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
9.5	47.3	GO:0051185	coenzyme transporter activity(GO:0051185)
9.3	74.1	GO:0031419	cobalamin binding(GO:0031419)
9.2	248.4	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
8.8	35.2	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
8.7	34.7	GO:0000104	succinate dehydrogenase activity(GO:0000104)
8.4	33.4	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
7.9	62.9	GO:0071253	connexin binding(GO:0071253)
6.8	27.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
6.7	26.6	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
6.6	26.4	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
6.4	19.2	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
6.4	19.2	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
6.4	44.5	GO:0061133	endopeptidase activator activity(GO:0061133)
6.3	25.0	GO:1904288	BAT3 complex binding(GO:1904288)
6.2	37.0	GO:0090599	alpha-glucosidase activity(GO:0090599)
6.1	49.1	GO:0031386	protein tag(GO:0031386)
5.7	17.2	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
5.6	78.7	GO:0016805	dipeptidase activity(GO:0016805)
5.6	16.7	GO:0000827	inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827)
5.5	49.3	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
5.4	54.3	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
5.4	27.1	GO:0089720	caspase binding(GO:0089720)
5.2	20.8	GO:0000293	ferric-chelate reductase activity(GO:0000293)
5.2	62.2	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
5.2	62.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
5.1	45.5	GO:0043495	protein anchor(GO:0043495)
5.0	40.4	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
4.9	108.5	GO:0003746	translation elongation factor activity(GO:0003746)
4.8	33.9	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
4.7	56.6	GO:0070008	serine-type exopeptidase activity(GO:0070008)
4.7	18.7	GO:0001156	TFIIIC-class transcription factor binding(GO:0001156)
4.5	13.5	GO:0048408	epidermal growth factor binding(GO:0048408)
4.5	17.8	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
4.4	30.6	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
4.3	34.7	GO:0034046	poly(G) binding(GO:0034046)
4.3	17.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
4.2	17.0	GO:0017089	glycolipid transporter activity(GO:0017089)
4.2	20.8	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
4.2	33.2	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
4.1	12.3	GO:0030156	benzodiazepine receptor binding(GO:0030156)
4.1	53.0	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
4.0	39.7	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
3.9	11.7	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
3.8	38.5	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
3.7	14.8	GO:0034618	arginine binding(GO:0034618)
3.7	99.4	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
3.7	14.6	GO:0043532	angiostatin binding(GO:0043532)
3.6	39.3	GO:0070513	death domain binding(GO:0070513)
3.6	107.0	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
3.5	10.5	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
3.4	10.3	GO:0036470	tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
3.4	304.1	GO:0051082	unfolded protein binding(GO:0051082)
3.4	13.7	GO:0000829	inositol heptakisphosphate kinase activity(GO:0000829)
3.3	13.1	GO:0005047	signal recognition particle binding(GO:0005047)
3.3	72.0	GO:0008327	methyl-CpG binding(GO:0008327)
3.2	16.1	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
3.2	25.3	GO:0004689	phosphorylase kinase activity(GO:0004689)
3.2	66.4	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
3.1	31.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
3.1	12.4	GO:1990955	G-rich single-stranded DNA binding(GO:1990955)
3.1	42.8	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
3.0	12.0	GO:0032050	clathrin heavy chain binding(GO:0032050)
2.9	20.6	GO:0017108	5'-flap endonuclease activity(GO:0017108)
2.8	8.5	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
2.8	34.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
2.7	19.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
2.7	10.7	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
2.6	34.0	GO:0008061	chitin binding(GO:0008061)
2.6	15.6	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
2.5	12.7	GO:0031685	adenosine receptor binding(GO:0031685)
2.5	7.6	GO:0044736	acid-sensing ion channel activity(GO:0044736)
2.5	74.4	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
2.5	37.2	GO:0043522	leucine zipper domain binding(GO:0043522)
2.5	9.8	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
2.4	19.4	GO:0046790	virion binding(GO:0046790)
2.4	2.4	GO:0034512	box C/D snoRNA binding(GO:0034512)
2.3	13.6	GO:1990226	histone methyltransferase binding(GO:1990226)
2.3	31.7	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.2	6.7	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
2.1	108.1	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
2.1	8.5	GO:0099609	microtubule lateral binding(GO:0099609)
2.0	32.3	GO:0046933	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
2.0	14.1	GO:0016018	cyclosporin A binding(GO:0016018)
2.0	12.0	GO:0098821	BMP receptor activity(GO:0098821)
2.0	6.0	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
2.0	27.9	GO:0000339	RNA cap binding(GO:0000339)
2.0	19.9	GO:0034511	U3 snoRNA binding(GO:0034511)
1.9	15.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
1.9	188.7	GO:0008565	protein transporter activity(GO:0008565)
1.9	5.6	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
1.8	11.1	GO:0008420	CTD phosphatase activity(GO:0008420)
1.8	29.0	GO:0008536	Ran GTPase binding(GO:0008536)
1.8	5.4	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
1.8	12.5	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
1.7	29.4	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
1.7	5.1	GO:0001031	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
1.7	11.6	GO:0008517	folic acid transporter activity(GO:0008517)
1.6	16.4	GO:0016929	SUMO-specific protease activity(GO:0016929)
1.6	75.4	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
1.6	29.6	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
1.5	26.1	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
1.5	63.3	GO:0005484	SNAP receptor activity(GO:0005484)
1.5	5.8	GO:0003987	acetate-CoA ligase activity(GO:0003987)
1.4	10.1	GO:0071532	ankyrin repeat binding(GO:0071532)
1.3	20.1	GO:0001671	ATPase activator activity(GO:0001671)
1.3	7.9	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.3	58.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.3	10.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.3	3.8	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
1.3	38.9	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
1.2	13.7	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
1.2	8.7	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
1.2	4.8	GO:0045322	unmethylated CpG binding(GO:0045322)
1.2	79.5	GO:0019888	protein phosphatase regulator activity(GO:0019888)
1.2	24.0	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
1.2	9.6	GO:0001163	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
1.2	26.1	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
1.2	8.2	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.1	29.7	GO:0071949	FAD binding(GO:0071949)
1.1	4.5	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
1.1	9.0	GO:0097602	cullin family protein binding(GO:0097602)
1.1	4.4	GO:0016149	translation release factor activity, codon specific(GO:0016149)
1.1	8.5	GO:0045545	syndecan binding(GO:0045545)
1.1	3.2	GO:0019961	interferon binding(GO:0019961)
1.0	9.4	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
1.0	2.1	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
1.0	8.3	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
1.0	18.3	GO:0005522	profilin binding(GO:0005522)
1.0	8.1	GO:0004673	protein histidine kinase activity(GO:0004673)
1.0	5.0	GO:0097016	L27 domain binding(GO:0097016)
1.0	4.0	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
1.0	5.8	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
1.0	6.8	GO:0034452	dynactin binding(GO:0034452)
1.0	14.3	GO:0032452	histone demethylase activity(GO:0032452)
0.9	5.5	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.9	110.5	GO:0047485	protein N-terminus binding(GO:0047485)
0.9	30.1	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.9	31.0	GO:0051059	NF-kappaB binding(GO:0051059)
0.9	25.4	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.9	7.2	GO:0001055	RNA polymerase II activity(GO:0001055)
0.9	38.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.9	12.1	GO:0045499	chemorepellent activity(GO:0045499)
0.9	17.3	GO:0031489	myosin V binding(GO:0031489)
0.9	2.6	GO:0001849	complement component C1q binding(GO:0001849)
0.9	6.0	GO:0050815	phosphoserine binding(GO:0050815)
0.9	4.3	GO:0034235	GPI anchor binding(GO:0034235)
0.9	20.4	GO:0070566	adenylyltransferase activity(GO:0070566)
0.8	31.3	GO:0019213	deacetylase activity(GO:0019213)
0.8	0.8	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.8	5.0	GO:0070878	primary miRNA binding(GO:0070878)
0.8	4.0	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.8	14.9	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.8	116.3	GO:0017137	Rab GTPase binding(GO:0017137)
0.8	7.6	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.8	3.8	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.7	9.6	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.7	3.7	GO:0001083	transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.7	20.5	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.7	8.6	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.7	2.1	GO:0030274	LIM domain binding(GO:0030274)
0.7	26.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.7	2.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.7	6.9	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.7	13.8	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.7	0.7	GO:0051870	methotrexate binding(GO:0051870)
0.7	2.0	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.7	7.5	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.7	2.0	GO:0009384	N-acylmannosamine kinase activity(GO:0009384)
0.7	27.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.6	20.6	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.6	6.4	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.6	180.9	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.6	0.6	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.6	8.2	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.6	1.7	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
0.6	4.5	GO:0030275	LRR domain binding(GO:0030275)
0.6	2.2	GO:0035514	DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.6	2.8	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.5	189.5	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.5	20.4	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.5	15.0	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.5	7.6	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.5	115.4	GO:0008236	serine-type peptidase activity(GO:0008236)
0.5	3.9	GO:0008494	translation activator activity(GO:0008494)
0.5	3.8	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.5	6.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.5	26.7	GO:0032947	protein complex scaffold(GO:0032947)
0.5	4.2	GO:0035198	miRNA binding(GO:0035198)
0.5	2.8	GO:0016531	copper chaperone activity(GO:0016531) cuprous ion binding(GO:1903136)
0.4	3.6	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4	6.3	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.4	23.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.4	5.9	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.4	5.0	GO:0015643	toxic substance binding(GO:0015643)
0.4	7.9	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.4	9.1	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4	9.9	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.4	10.8	GO:0043531	ADP binding(GO:0043531)
0.4	0.8	GO:0015137	citrate transmembrane transporter activity(GO:0015137)
0.4	14.0	GO:0051087	chaperone binding(GO:0051087)
0.4	3.9	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.4	7.7	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.4	70.3	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.4	6.0	GO:0050681	androgen receptor binding(GO:0050681)
0.4	6.0	GO:0005537	mannose binding(GO:0005537)
0.4	3.3	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.4	8.6	GO:0070491	repressing transcription factor binding(GO:0070491)
0.4	1.4	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.3	5.9	GO:0071837	HMG box domain binding(GO:0071837)
0.3	50.8	GO:0005179	hormone activity(GO:0005179)
0.3	1.3	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3	2.3	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.3	246.8	GO:0008270	zinc ion binding(GO:0008270)
0.3	3.3	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3	5.2	GO:0070402	NADPH binding(GO:0070402)
0.3	7.8	GO:0001540	beta-amyloid binding(GO:0001540)
0.3	66.8	GO:0004175	endopeptidase activity(GO:0004175)
0.3	2.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.3	1.7	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3	1.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.3	6.8	GO:0033613	activating transcription factor binding(GO:0033613)
0.3	16.6	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.3	0.5	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.3	66.7	GO:0003735	structural constituent of ribosome(GO:0003735)
0.3	101.6	GO:0046873	metal ion transmembrane transporter activity(GO:0046873)
0.3	3.6	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.2	3.9	GO:0042288	MHC class I protein binding(GO:0042288)
0.2	0.7	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.2	0.6	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.2	12.4	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.2	11.9	GO:0015405	primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405)
0.2	0.7	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.2	2.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.2	1.2	GO:0004565	beta-galactosidase activity(GO:0004565)
0.1	2.6	GO:0030331	estrogen receptor binding(GO:0030331)
0.1	2.2	GO:0016854	racemase and epimerase activity(GO:0016854)
0.1	0.7	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.1	0.9	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.7	GO:0070628	proteasome binding(GO:0070628)
0.1	5.4	GO:0008013	beta-catenin binding(GO:0008013)
0.1	5.1	GO:0002020	protease binding(GO:0002020)
0.1	1.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	2.3	GO:0016836	hydro-lyase activity(GO:0016836)
0.1	11.3	GO:0042277	peptide binding(GO:0042277)
0.1	2.7	GO:0070330	aromatase activity(GO:0070330)
0.1	2.2	GO:0005244	voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.1	0.5	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	2.1	GO:0097110	scaffold protein binding(GO:0097110)
0.1	6.2	GO:0020037	heme binding(GO:0020037) tetrapyrrole binding(GO:0046906)
0.1	0.7	GO:0015250	water channel activity(GO:0015250)
0.1	0.3	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	11.6	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.6	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.4	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	1.7	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.6	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.2	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.2	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.1	GO:1990254	keratin filament binding(GO:1990254)
0.0	35.8	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	1.4	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.3	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.5	GO:0030145	manganese ion binding(GO:0030145)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.9	100.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
3.0	78.6	PID ARF 3PATHWAY	Arf1 pathway
2.9	64.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
2.6	107.2	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
2.4	33.9	PID AP1 PATHWAY	AP-1 transcription factor network
2.4	31.4	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
1.7	59.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
1.5	27.1	ST G ALPHA S PATHWAY	G alpha s Pathway
1.5	14.9	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.3	56.9	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
1.2	34.1	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
1.2	43.2	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
1.2	22.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
1.1	36.4	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
1.1	12.8	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
1.1	71.7	PID MTOR 4PATHWAY	mTOR signaling pathway
1.0	32.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.8	21.7	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.8	6.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.8	13.6	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.7	9.5	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.7	18.1	PID MYC PATHWAY	C-MYC pathway
0.7	11.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.6	19.4	PID ALK1 PATHWAY	ALK1 signaling events
0.6	13.9	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.5	17.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.5	2.4	PID IL23 PATHWAY	IL23-mediated signaling events
0.5	30.1	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.4	27.7	PID P73PATHWAY	p73 transcription factor network
0.4	8.7	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.4	2.4	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.4	3.5	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.4	2.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.3	10.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.3	4.7	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.3	3.1	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.2	2.0	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.2	6.5	PID LKB1 PATHWAY	LKB1 signaling events
0.2	8.6	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.2	5.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.2	8.2	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.2	9.1	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	1.7	PID BARD1 PATHWAY	BARD1 signaling events
0.1	2.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.1	1.4	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.1	19.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	4.1	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.5	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	1.1	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	1.0	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.1	1.4	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	2.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.8	SIG CHEMOTAXIS	Genes related to chemotaxis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.5	85.4	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
7.5	135.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
7.1	114.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
5.9	307.3	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
5.8	69.8	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
5.6	343.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
5.3	142.9	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
5.0	15.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
4.8	81.8	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
4.7	66.0	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
3.9	94.4	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
3.9	38.6	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
3.9	46.2	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
3.5	62.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
3.4	67.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
3.4	140.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
3.0	15.2	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
2.9	23.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
2.7	54.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
2.7	69.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
2.7	72.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
2.7	42.8	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
2.6	71.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
2.6	163.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
2.6	40.9	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
2.4	43.4	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
2.4	63.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
2.2	26.1	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
2.1	37.4	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
2.0	30.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
2.0	67.0	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
2.0	22.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
2.0	86.3	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
2.0	23.9	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
1.9	26.1	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
1.9	14.8	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.6	38.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
1.5	27.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
1.4	18.7	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
1.3	15.7	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
1.2	10.9	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
1.2	29.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
1.2	11.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
1.0	33.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
1.0	17.1	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.9	11.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.9	41.7	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.9	20.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.9	11.9	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.8	40.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.8	18.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.7	5.9	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.6	10.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.6	5.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.5	6.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.5	10.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.5	10.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5	10.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.4	4.9	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.4	6.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.4	10.5	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.4	5.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4	60.4	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.4	9.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.4	7.6	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.3	3.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.3	37.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.3	17.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.3	4.0	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.3	8.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.3	28.1	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.3	4.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.2	3.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.2	26.7	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2	5.9	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	24.1	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.2	3.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	3.9	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.2	2.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	4.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	2.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	2.2	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	0.7	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.1	1.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	3.9	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	5.3	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.1	1.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	10.3	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions

Results for Etv3_Erf_Fev_Elk4_Elk1_Elk3

Z-value: 2.64

Motif logo

Transcription factors associated with Etv3_Erf_Fev_Elk4_Elk1_Elk3

Activity-expression correlation:

Activity profile of Etv3_Erf_Fev_Elk4_Elk1_Elk3 motif

Sorted Z-values of Etv3_Erf_Fev_Elk4_Elk1_Elk3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Etv3_Erf_Fev_Elk4_Elk1_Elk3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: