GSE53960: rat RNA-Seq transcriptomic Bodymap

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Erg Links NCBI RGD Ensembl	ENSRNOG00000001652	ERG, ETS transcription factor

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Erg	rn6_v1_chr11_-_35749464_35749594	0.71	1.3e-50	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_+_11077411 Show fit	126.34	ENSRNOT00000007117	S1pr4 Links NCBI RGD Ensembl Show fit	sphingosine-1-phosphate receptor 4
chr13_+_47602692 Show fit	96.83	ENSRNOT00000038822	Fcmr Links NCBI RGD Ensembl Show fit	Fc fragment of IgM receptor
chr13_+_89774764 Show fit	91.86	ENSRNOT00000005619	Arhgap30 Links NCBI RGD Ensembl Show fit	Rho GTPase activating protein 30
chr11_+_84745904 Show fit	84.06	ENSRNOT00000002617	Klhl6 Links NCBI RGD Ensembl Show fit	kelch-like family member 6
chr14_-_43992587 Show fit	78.69	ENSRNOT00000003425	Rhoh Links NCBI RGD Ensembl Show fit	ras homolog family member H
chr11_-_66759402 Show fit	76.47	ENSRNOT00000003326	Hcls1 Links NCBI RGD Ensembl Show fit	hematopoietic cell specific Lyn substrate 1
chr4_-_163227242 Show fit	74.36	ENSRNOT00000091552 ENSRNOT00000077793	Clec7a Links NCBI RGD Ensembl Show fit	C-type lectin domain family 7, member A
chr2_-_190100276 Show fit	74.08	ENSRNOT00000015351	S100a9 Links NCBI RGD Ensembl Show fit	S100 calcium binding protein A9
chrX_+_134979646 Show fit	71.11	ENSRNOT00000006035	Sash3 Links NCBI RGD Ensembl Show fit	SAM and SH3 domain containing 3
chr7_-_107392972 Show fit	70.73	ENSRNOT00000093425	Tmem71 Links NCBI RGD Ensembl Show fit	transmembrane protein 71
chr1_+_198744050 Show fit	70.09	ENSRNOT00000024404	Itgal Links NCBI RGD Ensembl Show fit	integrin subunit alpha L
chr13_+_50164563 Show fit	68.90	ENSRNOT00000029533	Lax1 Links NCBI RGD Ensembl Show fit	lymphocyte transmembrane adaptor 1
chr7_+_142776252 Show fit	68.77	ENSRNOT00000008673	Acvrl1 Links NCBI RGD Ensembl Show fit	activin A receptor like type 1
chr7_+_142776580 Show fit	67.34	ENSRNOT00000081047	Acvrl1 Links NCBI RGD Ensembl Show fit	activin A receptor like type 1
chr11_+_54619129 Show fit	65.22	ENSRNOT00000059924	Trat1 Links NCBI RGD Ensembl Show fit	T cell receptor associated transmembrane adaptor 1
chr1_-_227441442 Show fit	65.14	ENSRNOT00000028433	Ms4a1 Links NCBI RGD Ensembl Show fit	membrane spanning 4-domains A1
chr16_-_19918644 Show fit	64.50	ENSRNOT00000083345 ENSRNOT00000023926	Plvap Links NCBI RGD Ensembl Show fit	plasmalemma vesicle associated protein
chr1_-_197770669 Show fit	63.76	ENSRNOT00000023563	Lat Links NCBI RGD Ensembl Show fit	linker for activation of T cells
chr13_-_55173692 Show fit	61.65	ENSRNOT00000064785 ENSRNOT00000029878 ENSRNOT00000029865 ENSRNOT00000060292 ENSRNOT00000000814	Ptprc Links NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type, C
chr2_+_183674522 Show fit	61.02	ENSRNOT00000014433	Tmem154 Links NCBI RGD Ensembl Show fit	transmembrane protein 154
chr16_-_9430743 Show fit	60.47	ENSRNOT00000043811	Wdfy4 Links NCBI RGD Ensembl Show fit	WDFY family member 4
chr2_+_93792601 Show fit	58.18	ENSRNOT00000014701 ENSRNOT00000077311	Fabp4 Links NCBI RGD Ensembl Show fit	fatty acid binding protein 4
chr13_-_111917587 Show fit	57.18	ENSRNOT00000007649	Traf3ip3 Links NCBI RGD Ensembl Show fit	TRAF3 interacting protein 3
chr2_+_187218851 Show fit	57.03	ENSRNOT00000017798	Sh2d2a Links NCBI RGD Ensembl Show fit	SH2 domain containing 2A
chr20_+_30915213 Show fit	56.76	ENSRNOT00000000681	Prf1 Links NCBI RGD Ensembl Show fit	perforin 1
chr1_-_198577226 Show fit	55.65	ENSRNOT00000055013	Spn Links NCBI RGD Ensembl Show fit	sialophorin
chr8_-_49308806 Show fit	55.10	ENSRNOT00000047291	Cd3e Links NCBI RGD Ensembl Show fit	CD3e molecule
chr1_-_198662610 Show fit	54.39	ENSRNOT00000055012	Sept1 Links NCBI RGD Ensembl Show fit	septin 1
chr9_+_2190915 Show fit	53.66	ENSRNOT00000077417	Satb1 Links NCBI RGD Ensembl Show fit	SATB homeobox 1
chr5_-_147761983 Show fit	53.09	ENSRNOT00000012936	Lck Links NCBI RGD Ensembl Show fit	LCK proto-oncogene, Src family tyrosine kinase
chr1_-_206282575 Show fit	52.65	ENSRNOT00000024974	Adam12 Links NCBI RGD Ensembl Show fit	ADAM metallopeptidase domain 12
chr1_+_81763614 Show fit	52.56	ENSRNOT00000027254	Cd79a Links NCBI RGD Ensembl Show fit	CD79a molecule
chr1_-_17378047 Show fit	50.16	ENSRNOT00000020102	Themis Links NCBI RGD Ensembl Show fit	thymocyte selection associated
chr11_+_57108956 Show fit	49.53	ENSRNOT00000035485	Cd96 Links NCBI RGD Ensembl Show fit	CD96 molecule
chr19_+_19395655 Show fit	48.91	ENSRNOT00000019130	Snx20 Links NCBI RGD Ensembl Show fit	sorting nexin 20
chr1_+_42121636 Show fit	46.03	ENSRNOT00000025616	Myct1 Links NCBI RGD Ensembl Show fit	myc target 1
chrX_+_15155230 Show fit	45.98	ENSRNOT00000073289 ENSRNOT00000051439	Was Links NCBI RGD Ensembl Show fit	Wiskott-Aldrich syndrome
chr10_-_59112788 Show fit	45.49	ENSRNOT00000041886	Spns3 Links NCBI RGD Ensembl Show fit	SPNS sphingolipid transporter 3
chr6_+_98284170 Show fit	43.94	ENSRNOT00000031979	Rhoj Links NCBI RGD Ensembl Show fit	ras homolog family member J
chr10_+_47930633 Show fit	43.86	ENSRNOT00000003515	Grap Links NCBI RGD Ensembl Show fit	GRB2-related adaptor protein
chr11_-_35749464 Show fit	43.10	ENSRNOT00000078818 ENSRNOT00000078425	Erg Links NCBI RGD Ensembl Show fit	ERG, ETS transcription factor
chr1_+_166141954 Show fit	42.88	ENSRNOT00000042524	Fchsd2 Links NCBI RGD Ensembl Show fit	FCH and double SH3 domains 2
chr16_+_18716019 Show fit	42.50	ENSRNOT00000047870	Sftpa1 Links NCBI RGD Ensembl Show fit	surfactant protein A1
chr1_+_81779380 Show fit	42.26	ENSRNOT00000065865 ENSRNOT00000080143 ENSRNOT00000089592 ENSRNOT00000080840	Arhgef1 Links NCBI RGD Ensembl Show fit	Rho guanine nucleotide exchange factor 1
chr15_+_52451161 Show fit	39.72	ENSRNOT00000018725	Dok2 Links NCBI RGD Ensembl Show fit	docking protein 2
chr10_+_94566928 Show fit	39.16	ENSRNOT00000078446	Prr29 Links NCBI RGD Ensembl Show fit	proline rich 29
chr5_+_144160108 Show fit	38.94	ENSRNOT00000064972	Eva1b Links NCBI RGD Ensembl Show fit	eva-1 homolog B
chr5_+_149056078 Show fit	37.77	ENSRNOT00000083028	Laptm5 Links NCBI RGD Ensembl Show fit	lysosomal protein transmembrane 5
chr2_-_47281421 Show fit	37.51	ENSRNOT00000086114	Itga1 Links NCBI RGD Ensembl Show fit	integrin subunit alpha 1
chr3_+_28627084 Show fit	37.33	ENSRNOT00000049884	Arhgap15 Links NCBI RGD Ensembl Show fit	Rho GTPase activating protein 15
chr10_-_5260608 Show fit	37.15	ENSRNOT00000003572	Ciita Links NCBI RGD Ensembl Show fit	class II, major histocompatibility complex, transactivator
chrX_+_14578264 Show fit	36.31	ENSRNOT00000038994	Cybb Links NCBI RGD Ensembl Show fit	cytochrome b-245 beta chain
chr2_+_206342066 Show fit	36.31	ENSRNOT00000026556	Ptpn22 Links NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 22
chr4_-_78342863 Show fit	36.23	ENSRNOT00000049038	Gimap6 Links NCBI RGD Ensembl Show fit	GTPase, IMAP family member 6
chr1_-_14412807 Show fit	36.09	ENSRNOT00000074583	Tnfaip3 Links NCBI RGD Ensembl Show fit	TNF alpha induced protein 3
chr6_-_79306443 Show fit	35.90	ENSRNOT00000030706	Clec14a Links NCBI RGD Ensembl Show fit	C-type lectin domain family 14, member A
chr13_+_83996080 Show fit	35.60	ENSRNOT00000004403 ENSRNOT00000070958	Cd247 Links NCBI RGD Ensembl Show fit	Cd247 molecule
chrX_+_78259409 Show fit	35.44	ENSRNOT00000049779	RGD1560455 Links NCBI RGD Ensembl Show fit	similar to RIKEN cDNA A630033H20 gene
chr18_-_28535828 Show fit	35.14	ENSRNOT00000068386	Tmem173 Links NCBI RGD Ensembl Show fit	transmembrane protein 173
chr13_+_74456487 Show fit	34.85	ENSRNOT00000065801	Angptl1 Links NCBI RGD Ensembl Show fit	angiopoietin-like 1
chr8_+_60760078 Show fit	34.23	ENSRNOT00000063930	Pstpip1 Links NCBI RGD Ensembl Show fit	proline-serine-threonine phosphatase-interacting protein 1
chr7_-_119716238 Show fit	32.72	ENSRNOT00000075678	Il2rb Links NCBI RGD Ensembl Show fit	interleukin 2 receptor subunit beta
chr16_-_74710704 Show fit	32.72	ENSRNOT00000016859	Thsd1 Links NCBI RGD Ensembl Show fit	thrombospondin type 1 domain containing 1
chr4_+_90990088 Show fit	32.68	ENSRNOT00000030320	Mmrn1 Links NCBI RGD Ensembl Show fit	multimerin 1
chr9_+_65620658 Show fit	32.66	ENSRNOT00000084498	Casp8 Links NCBI RGD Ensembl Show fit	caspase 8
chr3_+_93920447 Show fit	32.50	ENSRNOT00000012625	Lmo2 Links NCBI RGD Ensembl Show fit	LIM domain only 2
chr2_-_105047984 Show fit	32.04	ENSRNOT00000014970	Cpa3 Links NCBI RGD Ensembl Show fit	carboxypeptidase A3
chr9_+_94745217 Show fit	31.95	ENSRNOT00000051338	Inpp5d Links NCBI RGD Ensembl Show fit	inositol polyphosphate-5-phosphatase D
chr9_+_2202511 Show fit	31.77	ENSRNOT00000017556	Satb1 Links NCBI RGD Ensembl Show fit	SATB homeobox 1
chr5_+_154522119 Show fit	31.58	ENSRNOT00000072618	E2f2 Links NCBI RGD Ensembl Show fit	E2F transcription factor 2
chr1_-_56683731 Show fit	31.55	ENSRNOT00000014552	Thbs2 Links NCBI RGD Ensembl Show fit	thrombospondin 2
chr4_+_71740532 Show fit	31.32	ENSRNOT00000023537	Zyx Links NCBI RGD Ensembl Show fit	zyxin
chr5_-_79222687 Show fit	31.31	ENSRNOT00000010516	Akna Links NCBI RGD Ensembl Show fit	AT-hook transcription factor
chr2_-_198002625 Show fit	31.26	ENSRNOT00000091888	BC028528 Links NCBI RGD Ensembl Show fit	cDNA sequence BC028528
chr5_-_137321121 Show fit	30.96	ENSRNOT00000027414	Tie1 Links NCBI RGD Ensembl Show fit	tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr7_+_70614617 Show fit	30.17	ENSRNOT00000035382	Arhgap9 Links NCBI RGD Ensembl Show fit	Rho GTPase activating protein 9
chr13_+_88606894 Show fit	29.93	ENSRNOT00000048692	Sh2d1b Links NCBI RGD Ensembl Show fit	SH2 domain containing 1B
chr13_-_50761306 Show fit	29.65	ENSRNOT00000076610 ENSRNOT00000004241	Prelp Links NCBI RGD Ensembl Show fit	proline and arginine rich end leucine rich repeat protein
chr17_+_22984844 Show fit	28.81	ENSRNOT00000078310	Nedd9 Links NCBI RGD Ensembl Show fit	neural precursor cell expressed, developmentally down-regulated 9
chr1_-_216918969 Show fit	28.75	ENSRNOT00000079454	Osbpl5 Links NCBI RGD Ensembl Show fit	oxysterol binding protein-like 5
chr10_+_75088422 Show fit	28.63	ENSRNOT00000081951	Mpo Links NCBI RGD Ensembl Show fit	myeloperoxidase
chr20_+_9948908 Show fit	28.48	ENSRNOT00000001541	Ubash3a Links NCBI RGD Ensembl Show fit	ubiquitin associated and SH3 domain containing, A
chr1_-_89474252 Show fit	28.11	ENSRNOT00000028597	Fxyd5 Links NCBI RGD Ensembl Show fit	FXYD domain-containing ion transport regulator 5
chr4_-_44136815 Show fit	28.09	ENSRNOT00000086810	Tfec Links NCBI RGD Ensembl Show fit	transcription factor EC
chr15_-_34469350 Show fit	27.93	ENSRNOT00000067536	Adcy4 Links NCBI RGD Ensembl Show fit	adenylate cyclase 4
chr5_-_59025631 Show fit	27.80	ENSRNOT00000049000 ENSRNOT00000022801	Tpm2 Links NCBI RGD Ensembl Show fit	tropomyosin 2, beta
chr3_-_91370167 Show fit	27.70	ENSRNOT00000006291	Prr5l Links NCBI RGD Ensembl Show fit	proline rich 5 like
chr11_+_67082193 Show fit	27.67	ENSRNOT00000003129	Cd86 Links NCBI RGD Ensembl Show fit	CD86 molecule
chr9_+_52023295 Show fit	27.65	ENSRNOT00000004956	Col3a1 Links NCBI RGD Ensembl Show fit	collagen type III alpha 1 chain
chr11_+_64601029 Show fit	27.24	ENSRNOT00000004138	Arhgap31 Links NCBI RGD Ensembl Show fit	Rho GTPase activating protein 31
chr2_+_32820322 Show fit	27.14	ENSRNOT00000013768	Cd180 Links NCBI RGD Ensembl Show fit	CD180 molecule
chr1_-_199823386 Show fit	26.99	ENSRNOT00000027375	Rgs10 Links NCBI RGD Ensembl Show fit	regulator of G-protein signaling 10
chrX_-_77700269 Show fit	26.39	ENSRNOT00000092418	Cysltr1 Links NCBI RGD Ensembl Show fit	cysteinyl leukotriene receptor 1
chr1_-_89473904 Show fit	26.36	ENSRNOT00000089474	Fxyd5 Links NCBI RGD Ensembl Show fit	FXYD domain-containing ion transport regulator 5
chr10_+_35133252 Show fit	26.16	ENSRNOT00000051916	Scgb3a1 Links NCBI RGD Ensembl Show fit	secretoglobin, family 3A, member 1
chr4_-_157263890 Show fit	26.03	ENSRNOT00000065416	Ptpn6 Links NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 6
chrX_+_1311121 Show fit	26.01	ENSRNOT00000038909	Cfp Links NCBI RGD Ensembl Show fit	complement factor properdin
chr10_+_77537340 Show fit	25.94	ENSRNOT00000003297	Tmem100 Links NCBI RGD Ensembl Show fit	transmembrane protein 100
chr3_+_93920013 Show fit	25.79	ENSRNOT00000083527	Lmo2 Links NCBI RGD Ensembl Show fit	LIM domain only 2
chr14_-_81023682 Show fit	25.79	ENSRNOT00000081570	Rgs12 Links NCBI RGD Ensembl Show fit	regulator of G-protein signaling 12
chr3_-_153001309 Show fit	25.77	ENSRNOT00000027581	Sla2 Links NCBI RGD Ensembl Show fit	Src-like-adaptor 2
chr1_+_88875375 Show fit	25.68	ENSRNOT00000028284	Tyrobp Links NCBI RGD Ensembl Show fit	Tyro protein tyrosine kinase binding protein
chr8_+_104106740 Show fit	25.55	ENSRNOT00000015015	Tfdp2 Links NCBI RGD Ensembl Show fit	transcription factor Dp-2
chr10_-_14443010 Show fit	25.51	ENSRNOT00000022142	Tmem204 Links NCBI RGD Ensembl Show fit	transmembrane protein 204
chr9_+_67699379 Show fit	25.48	ENSRNOT00000091237 ENSRNOT00000088183	Ctla4 Links NCBI RGD Ensembl Show fit	cytotoxic T-lymphocyte-associated protein 4
chr18_+_44716226 Show fit	25.39	ENSRNOT00000086431	Tnfaip8 Links NCBI RGD Ensembl Show fit	TNF alpha induced protein 8
chr3_+_79918969 Show fit	25.00	ENSRNOT00000016306	Spi1 Links NCBI RGD Ensembl Show fit	Spi-1 proto-oncogene
chr9_+_42871950 Show fit	24.96	ENSRNOT00000089673	Arid5a Links NCBI RGD Ensembl Show fit	AT-rich interaction domain 5A
chr5_+_153507093 Show fit	24.86	ENSRNOT00000086650 ENSRNOT00000083645	Runx3 Links NCBI RGD Ensembl Show fit	runt-related transcription factor 3
chr2_+_212257225 Show fit	24.80	ENSRNOT00000077883	Vav3 Links NCBI RGD Ensembl Show fit	vav guanine nucleotide exchange factor 3
chr9_+_46657922 Show fit	24.73	ENSRNOT00000019180	Map4k4 Links NCBI RGD Ensembl Show fit	mitogen-activated protein kinase kinase kinase kinase 4
chr3_+_110367939 Show fit	24.69	ENSRNOT00000010406	Bub1b Links NCBI RGD Ensembl Show fit	BUB1 mitotic checkpoint serine/threonine kinase B
chr8_+_133210473 Show fit	24.49	ENSRNOT00000082774	Ccr5 Links NCBI RGD Ensembl Show fit	chemokine (C-C motif) receptor 5
chr7_+_70612103 Show fit	24.43	ENSRNOT00000057833	Arhgap9 Links NCBI RGD Ensembl Show fit	Rho GTPase activating protein 9
chr20_+_7788084 Show fit	23.94	ENSRNOT00000000597	Def6 Links NCBI RGD Ensembl Show fit	DEF6 guanine nucleotide exchange factor
chr16_-_7250924 Show fit	23.88	ENSRNOT00000025394	Stab1 Links NCBI RGD Ensembl Show fit	stabilin 1
chr8_+_102304095 Show fit	23.81	ENSRNOT00000011358	Slc9a9 Links NCBI RGD Ensembl Show fit	solute carrier family 9 member A9
chr4_+_158088505 Show fit	23.10	ENSRNOT00000026643	Vwf Links NCBI RGD Ensembl Show fit	von Willebrand factor
chr3_+_4034921 Show fit	23.03	ENSRNOT00000026318	Egfl7 Links NCBI RGD Ensembl Show fit	EGF-like-domain, multiple 7
chr11_+_64882288 Show fit	22.95	ENSRNOT00000077727	Pla1a Links NCBI RGD Ensembl Show fit	phospholipase A1 member A
chr10_+_56764927 Show fit	22.56	ENSRNOT00000025308	Clec10a Links NCBI RGD Ensembl Show fit	C-type lectin domain family 10, member A
chr20_+_9743269 Show fit	21.78	ENSRNOT00000001533 ENSRNOT00000083505	Abcg1 Links NCBI RGD Ensembl Show fit	ATP binding cassette subfamily G member 1
chr12_+_9034308 Show fit	21.78	ENSRNOT00000001248	Flt1 Links NCBI RGD Ensembl Show fit	FMS-related tyrosine kinase 1
chr6_+_12362813 Show fit	21.71	ENSRNOT00000022370	Ston1 Links NCBI RGD Ensembl Show fit	stonin 1
chr1_-_24191908 Show fit	21.58	ENSRNOT00000061157	Sgk1 Links NCBI RGD Ensembl Show fit	serum/glucocorticoid regulated kinase 1
chr3_+_11679530 Show fit	21.57	ENSRNOT00000074562 ENSRNOT00000071801	Eng Links NCBI RGD Ensembl Show fit	endoglin
chr2_-_206222248 Show fit	21.13	ENSRNOT00000026075	Olfml3 Links NCBI RGD Ensembl Show fit	olfactomedin-like 3
chr15_-_42898150 Show fit	20.69	ENSRNOT00000030036	Ptk2b Links NCBI RGD Ensembl Show fit	protein tyrosine kinase 2 beta
chrX_-_38196060 Show fit	20.36	ENSRNOT00000006741 ENSRNOT00000006438	Sh3kbp1 Links NCBI RGD Ensembl Show fit	SH3 domain-containing kinase-binding protein 1
chr7_-_143852119 Show fit	20.21	ENSRNOT00000016801	Rarg Links NCBI RGD Ensembl Show fit	retinoic acid receptor, gamma
chr11_-_60882379 Show fit	20.02	ENSRNOT00000002799	Cd200r1 Links NCBI RGD Ensembl Show fit	CD200 receptor 1
chr10_-_106781950 Show fit	19.99	ENSRNOT00000077495	Tmc6 Links NCBI RGD Ensembl Show fit	transmembrane channel-like gene family 6
chr5_+_122019301 Show fit	19.67	ENSRNOT00000068158	Pde4b Links NCBI RGD Ensembl Show fit	phosphodiesterase 4B
chr2_+_242634399 Show fit	19.55	ENSRNOT00000035700	Emcn Links NCBI RGD Ensembl Show fit	endomucin
chr4_+_156253079 Show fit	19.44	ENSRNOT00000013536	Clec4d Links NCBI RGD Ensembl Show fit	C-type lectin domain family 4, member D
chr18_-_6082997 Show fit	19.43	ENSRNOT00000086335 ENSRNOT00000032454	Ss18 Links NCBI RGD Ensembl Show fit	SS18, nBAF chromatin remodeling complex subunit
chr5_-_160158386 Show fit	19.35	ENSRNOT00000089345	Fblim1 Links NCBI RGD Ensembl Show fit	filamin binding LIM protein 1
chr5_-_70463546 Show fit	19.34	ENSRNOT00000043184	AC118841.1 Links NCBI RGD Ensembl Show fit
chr13_+_52645257 Show fit	19.18	ENSRNOT00000012801	Lad1 Links NCBI RGD Ensembl Show fit	ladinin 1
chrX_-_84167717 Show fit	19.02	ENSRNOT00000006415	Pof1b Links NCBI RGD Ensembl Show fit	premature ovarian failure 1B
chrX_+_18998532 Show fit	18.99	ENSRNOT00000004213	AABR07037343.1 Links NCBI RGD Ensembl Show fit
chr10_+_17421075 Show fit	18.90	ENSRNOT00000047011	Stk10 Links NCBI RGD Ensembl Show fit	serine/threonine kinase 10
chr8_-_32280869 Show fit	18.90	ENSRNOT00000009139	St14 Links NCBI RGD Ensembl Show fit	suppression of tumorigenicity 14
chr20_-_32133431 Show fit	18.71	ENSRNOT00000000443	Srgn Links NCBI RGD Ensembl Show fit	serglycin
chr18_-_24312950 Show fit	18.68	ENSRNOT00000051911	LOC686074 Links NCBI RGD Ensembl Show fit	similar to 60S ribosomal protein L35
chr8_-_72204730 Show fit	18.50	ENSRNOT00000023810	Fbxl22 Links NCBI RGD Ensembl Show fit	F-box and leucine-rich repeat protein 22
chr9_-_20195566 Show fit	18.15	ENSRNOT00000015223	Adgrf5 Links NCBI RGD Ensembl Show fit	adhesion G protein-coupled receptor F5
chr10_-_56300077 Show fit	18.11	ENSRNOT00000064401	Tnfsf12 Links NCBI RGD Ensembl Show fit	tumor necrosis factor superfamily member 12
chr15_-_108326907 Show fit	18.01	ENSRNOT00000016848	Gpr18 Links NCBI RGD Ensembl Show fit	G protein-coupled receptor 18
chr8_+_22559098 Show fit	17.95	ENSRNOT00000041091	LOC691141 Links NCBI RGD Ensembl Show fit	hypothetical protein LOC691141
chr2_-_189573280 Show fit	17.91	ENSRNOT00000022897	Rps27 Links NCBI RGD Ensembl Show fit	ribosomal protein S27
chr10_-_40764185 Show fit	17.90	ENSRNOT00000017486	Sparc Links NCBI RGD Ensembl Show fit	secreted protein acidic and cysteine rich
chr6_+_50528823 Show fit	17.82	ENSRNOT00000008321	Lamb1 Links NCBI RGD Ensembl Show fit	laminin subunit beta 1
chr18_+_56379890 Show fit	17.78	ENSRNOT00000078764	Pdgfrb Links NCBI RGD Ensembl Show fit	platelet derived growth factor receptor beta
chr3_-_63568464 Show fit	17.36	ENSRNOT00000068494	AABR07052585.2 Links NCBI RGD Ensembl Show fit
chr17_-_78812111 Show fit	16.99	ENSRNOT00000021506	Dclre1c Links NCBI RGD Ensembl Show fit	DNA cross-link repair 1C
chr4_-_155051429 Show fit	16.80	ENSRNOT00000020094	Klrg1 Links NCBI RGD Ensembl Show fit	killer cell lectin like receptor G1
chr9_-_29647903 Show fit	16.78	ENSRNOT00000019062	Ogfrl1 Links NCBI RGD Ensembl Show fit	opioid growth factor receptor-like 1
chr5_+_82587420 Show fit	16.31	ENSRNOT00000014020	Tlr4 Links NCBI RGD Ensembl Show fit	toll-like receptor 4
chr3_+_140024043 Show fit	16.30	ENSRNOT00000086409	Rin2 Links NCBI RGD Ensembl Show fit	Ras and Rab interactor 2
chr4_+_28989115 Show fit	15.97	ENSRNOT00000075326	Gng11 Links NCBI RGD Ensembl Show fit	G protein subunit gamma 11
chr1_-_90149991 Show fit	15.77	ENSRNOT00000076987	RGD1308428 Links NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 4931406P16
chr4_+_167754525 Show fit	15.76	ENSRNOT00000007889	Etv6 Links NCBI RGD Ensembl Show fit	ets variant 6
chr2_+_187988925 Show fit	15.69	ENSRNOT00000093033 ENSRNOT00000093016	Arhgef2 Links NCBI RGD Ensembl Show fit	Rho/Rac guanine nucleotide exchange factor 2
chr15_+_67555835 Show fit	15.68	ENSRNOT00000045882	Pcdh17 Links NCBI RGD Ensembl Show fit	protocadherin 17
chr7_+_59326518 Show fit	15.37	ENSRNOT00000085231	Ptprb Links NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type, B
chr11_-_14304603 Show fit	15.35	ENSRNOT00000040202 ENSRNOT00000082143	Samsn1 Links NCBI RGD Ensembl Show fit	SAM domain, SH3 domain and nuclear localization signals, 1
chr16_-_21362955 Show fit	15.27	ENSRNOT00000039607	Gmip Links NCBI RGD Ensembl Show fit	Gem-interacting protein
chr2_-_149325913 Show fit	14.79	ENSRNOT00000036690	Gpr171 Links NCBI RGD Ensembl Show fit	G protein-coupled receptor 171
chr4_+_31387420 Show fit	14.62	ENSRNOT00000074048	LOC100912034 Links NCBI RGD Ensembl Show fit	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11-like
chr10_+_63662986 Show fit	14.39	ENSRNOT00000088722	Scarf1 Links NCBI RGD Ensembl Show fit	scavenger receptor class F, member 1
chr5_+_104362971 Show fit	14.38	ENSRNOT00000058520	Adamtsl1 Links NCBI RGD Ensembl Show fit	ADAMTS-like 1
chr13_-_108841482 Show fit	14.30	ENSRNOT00000004632 ENSRNOT00000086775	Ptpn14 Links NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 14
chr4_-_165317573 Show fit	14.10	ENSRNOT00000087529 ENSRNOT00000080017	Klra5 Links NCBI RGD Ensembl Show fit	killer cell lectin-like receptor, subfamily A, member 5
chrX_+_40460047 Show fit	14.03	ENSRNOT00000010970	Phex Links NCBI RGD Ensembl Show fit	phosphate regulating endopeptidase homolog, X-linked
chr10_+_75087892 Show fit	14.03	ENSRNOT00000065910	Mpo Links NCBI RGD Ensembl Show fit	myeloperoxidase
chr8_-_132178217 Show fit	13.93	ENSRNOT00000087427	Zdhhc3 Links NCBI RGD Ensembl Show fit	zinc finger, DHHC-type containing 3
chr5_+_144031402 Show fit	13.52	ENSRNOT00000011694	Csf3r Links NCBI RGD Ensembl Show fit	colony stimulating factor 3 receptor
chr17_-_46794845 Show fit	13.44	ENSRNOT00000077910 ENSRNOT00000090663 ENSRNOT00000078331	Elmo1 Links NCBI RGD Ensembl Show fit	engulfment and cell motility 1
chr11_-_51202703 Show fit	13.44	ENSRNOT00000002719 ENSRNOT00000077220	Cblb Links NCBI RGD Ensembl Show fit	Cbl proto-oncogene B
chr9_+_69497121 Show fit	13.42	ENSRNOT00000042562	Nrp2 Links NCBI RGD Ensembl Show fit	neuropilin 2
chr1_+_214440503 Show fit	13.38	ENSRNOT00000025964	Cracr2b Links NCBI RGD Ensembl Show fit	calcium release activated channel regulator 2B
chr14_-_35581031 Show fit	13.16	ENSRNOT00000003077	Pdgfra Links NCBI RGD Ensembl Show fit	platelet derived growth factor receptor alpha
chr10_-_39604070 Show fit	13.13	ENSRNOT00000032333	Csf2 Links NCBI RGD Ensembl Show fit	colony stimulating factor 2
chr10_-_90912287 Show fit	13.06	ENSRNOT00000093570	Gjc1 Links NCBI RGD Ensembl Show fit	gap junction protein, gamma 1
chr10_-_104358253 Show fit	13.02	ENSRNOT00000005942	Caskin2 Links NCBI RGD Ensembl Show fit	cask-interacting protein 2
chr12_-_24537313 Show fit	12.76	ENSRNOT00000001975	Baz1b Links NCBI RGD Ensembl Show fit	bromodomain adjacent to zinc finger domain, 1B
chr11_+_82680253 Show fit	12.63	ENSRNOT00000077119 ENSRNOT00000075512	Liph Links NCBI RGD Ensembl Show fit	lipase H
chr11_-_33003021 Show fit	12.38	ENSRNOT00000084134	Runx1 Links NCBI RGD Ensembl Show fit	runt-related transcription factor 1
chr16_-_56900052 Show fit	12.23	ENSRNOT00000017339	Msr1 Links NCBI RGD Ensembl Show fit	macrophage scavenger receptor 1
chr5_+_163612518 Show fit	12.15	ENSRNOT00000071103	LOC103692519 Links NCBI RGD Ensembl Show fit	60S ribosomal protein L9 pseudogene
chr3_-_119135391 Show fit	11.90	ENSRNOT00000045443	Gabpb1 Links NCBI RGD Ensembl Show fit	GA binding protein transcription factor, beta subunit 1
chr20_+_5646097 Show fit	11.72	ENSRNOT00000090925	Itpr3 Links NCBI RGD Ensembl Show fit	inositol 1,4,5-trisphosphate receptor, type 3
chr17_+_9837402 Show fit	11.56	ENSRNOT00000076436	Rab24 Links NCBI RGD Ensembl Show fit	RAB24, member RAS oncogene family
chr3_+_151691515 Show fit	11.44	ENSRNOT00000052236	AC118414.1 Links NCBI RGD Ensembl Show fit
chr5_-_137238354 Show fit	11.15	ENSRNOT00000039235	Szt2 Links NCBI RGD Ensembl Show fit	seizure threshold 2 homolog (mouse)
chr12_+_13090172 Show fit	11.11	ENSRNOT00000092558	Rac1 Links NCBI RGD Ensembl Show fit	ras-related C3 botulinum toxin substrate 1
chr3_-_11102515 Show fit	10.96	ENSRNOT00000035580	Fam78a Links NCBI RGD Ensembl Show fit	family with sequence similarity 78, member A
chr11_-_61499557 Show fit	10.89	ENSRNOT00000046208	Usf3 Links NCBI RGD Ensembl Show fit	upstream transcription factor family member 3
chr10_-_32471454 Show fit	10.72	ENSRNOT00000003224	Sgcd Links NCBI RGD Ensembl Show fit	sarcoglycan, delta

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
24.1	72.4	GO:0070425	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
20.6	61.7	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
20.1	200.8	GO:0090500	endocardial cushion to mesenchymal transition(GO:0090500)
19.1	76.5	GO:0042509	regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
18.6	74.4	GO:0071226	cellular response to molecule of fungal origin(GO:0071226)
18.6	55.7	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
18.5	55.6	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
18.1	54.4	GO:0007056	spindle assembly involved in female meiosis(GO:0007056)
14.2	42.7	GO:0002148	hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
12.4	49.5	GO:0002727	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
12.1	36.3	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
11.5	171.8	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
10.8	64.8	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
9.2	27.7	GO:0002644	negative regulation of tolerance induction(GO:0002644)
8.8	96.8	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
8.2	24.5	GO:2000464	positive regulation of astrocyte chemotaxis(GO:2000464)
8.2	65.2	GO:0001920	negative regulation of receptor recycling(GO:0001920)
8.0	31.9	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
7.7	30.9	GO:0072276	VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
7.7	46.0	GO:0002457	T cell antigen processing and presentation(GO:0002457)
7.6	53.1	GO:0046645	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
7.4	103.4	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
7.2	50.3	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
7.0	70.1	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
6.9	27.7	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
6.9	20.7	GO:0010752	regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
6.8	94.8	GO:0002467	germinal center formation(GO:0002467)
6.7	20.2	GO:0003430	growth plate cartilage chondrocyte growth(GO:0003430)
6.6	19.9	GO:0010070	zygote asymmetric cell division(GO:0010070)
6.5	32.7	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
6.4	25.5	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
6.3	31.6	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
6.2	25.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
6.2	18.7	GO:0033364	mast cell secretory granule organization(GO:0033364)
6.2	37.1	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
5.9	17.8	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
5.9	71.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
5.8	23.3	GO:0071802	negative regulation of podosome assembly(GO:0071802)
5.4	21.8	GO:0034436	glycoprotein transport(GO:0034436) response to high density lipoprotein particle(GO:0055099)
5.3	58.3	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
5.2	25.9	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
4.9	24.7	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
4.9	19.6	GO:0032707	negative regulation of interleukin-23 production(GO:0032707)
4.7	18.9	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
4.7	42.5	GO:0008228	opsonization(GO:0008228)
4.5	13.4	GO:0021649	vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
4.4	26.4	GO:0061737	leukotriene signaling pathway(GO:0061737)
4.3	25.8	GO:0023021	termination of signal transduction(GO:0023021)
4.3	17.2	GO:0033277	abortive mitotic cell cycle(GO:0033277)
4.1	12.4	GO:2000872	positive regulation of progesterone secretion(GO:2000872)
3.9	15.8	GO:0007296	vitellogenesis(GO:0007296)
3.9	50.2	GO:0043383	negative T cell selection(GO:0043383)
3.8	56.8	GO:0001771	immunological synapse formation(GO:0001771)
3.6	21.8	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
3.6	43.5	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
3.6	32.0	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
3.5	10.5	GO:1904383	response to sodium phosphate(GO:1904383)
3.5	10.5	GO:0031583	phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
3.4	6.9	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
3.4	30.6	GO:2001204	regulation of osteoclast development(GO:2001204)
3.3	13.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
3.3	13.1	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
3.2	19.4	GO:0038203	TORC2 signaling(GO:0038203)
3.2	22.6	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
3.2	35.1	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
3.1	62.7	GO:0050872	white fat cell differentiation(GO:0050872)
3.0	48.6	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
3.0	32.7	GO:0060546	negative regulation of necroptotic process(GO:0060546)
2.8	17.0	GO:0038096	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
2.8	8.4	GO:0060939	myofibroblast differentiation(GO:0036446) cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939) regulation of myofibroblast differentiation(GO:1904760)
2.7	41.0	GO:0033591	response to L-ascorbic acid(GO:0033591)
2.6	68.9	GO:0000188	inactivation of MAPK activity(GO:0000188)
2.6	10.2	GO:0090309	DNA methylation on cytosine within a CG sequence(GO:0010424) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
2.4	19.4	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
2.4	21.6	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
2.4	7.1	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
2.3	14.0	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
2.3	77.4	GO:0050853	B cell receptor signaling pathway(GO:0050853)
2.3	18.1	GO:0071073	positive regulation of phospholipid biosynthetic process(GO:0071073)
2.3	4.5	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
2.2	37.5	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
2.1	12.8	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
2.1	17.0	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
2.1	10.3	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
2.0	28.5	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
2.0	25.8	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
2.0	7.9	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
1.9	5.8	GO:0098972	dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
1.9	5.8	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160)
1.9	24.7	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.9	13.3	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
1.9	39.8	GO:0001945	lymph vessel development(GO:0001945)
1.9	142.5	GO:0045576	mast cell activation(GO:0045576)
1.9	5.6	GO:0000105	histidine biosynthetic process(GO:0000105)
1.9	11.2	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
1.8	23.8	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.8	8.9	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.8	14.2	GO:0044154	histone H3-K14 acetylation(GO:0044154)
1.7	5.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
1.6	26.2	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
1.6	4.9	GO:2001268	response to high light intensity(GO:0009644) cellular response to iron(III) ion(GO:0071283) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
1.6	4.8	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
1.6	15.7	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
1.5	4.5	GO:0002191	cap-dependent translational initiation(GO:0002191) positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
1.5	19.3	GO:0033623	regulation of integrin activation(GO:0033623)
1.5	24.9	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
1.4	10.1	GO:0043654	recognition of apoptotic cell(GO:0043654)
1.4	12.2	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
1.3	4.0	GO:1904178	sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
1.3	35.4	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
1.2	14.4	GO:0048680	positive regulation of axon regeneration(GO:0048680)
1.1	3.3	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301) negative regulation of neutrophil degranulation(GO:0043314) negative regulation of neutrophil activation(GO:1902564)
1.1	35.6	GO:0050852	T cell receptor signaling pathway(GO:0050852)
1.1	35.9	GO:0002042	cell migration involved in sprouting angiogenesis(GO:0002042)
1.0	6.3	GO:0006910	phagocytosis, recognition(GO:0006910)
1.0	9.3	GO:0043416	regulation of skeletal muscle tissue regeneration(GO:0043416)
1.0	25.0	GO:0035066	positive regulation of histone acetylation(GO:0035066)
1.0	13.4	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
1.0	44.9	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.9	7.3	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.9	6.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.9	31.0	GO:0045026	plasma membrane fusion(GO:0045026)
0.8	19.4	GO:0097150	neuronal stem cell population maintenance(GO:0097150)
0.8	5.8	GO:0016081	synaptic vesicle docking(GO:0016081)
0.8	2.5	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.8	3.3	GO:0008355	olfactory learning(GO:0008355)
0.8	8.7	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.8	6.3	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.8	2.3	GO:0036438	maintenance of lens transparency(GO:0036438)
0.8	23.7	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.7	2.9	GO:0030242	pexophagy(GO:0030242)
0.7	6.2	GO:0080009	mRNA methylation(GO:0080009)
0.7	9.5	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.6	4.5	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.6	10.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.6	17.3	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.6	13.4	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.6	35.7	GO:0015914	phospholipid transport(GO:0015914)
0.6	25.4	GO:0032611	interleukin-1 beta production(GO:0032611)
0.6	1.2	GO:0060661	submandibular salivary gland formation(GO:0060661) positive regulation of hair follicle cell proliferation(GO:0071338)
0.6	9.6	GO:0010669	epithelial structure maintenance(GO:0010669)
0.6	23.9	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.6	6.8	GO:0005513	detection of calcium ion(GO:0005513)
0.6	4.0	GO:0006013	mannose metabolic process(GO:0006013) protein deglycosylation(GO:0006517)
0.6	9.0	GO:0030220	platelet formation(GO:0030220)
0.6	6.1	GO:0097284	hepatocyte apoptotic process(GO:0097284)
0.6	54.6	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.5	10.4	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.5	2.1	GO:0010286	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.5	31.8	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.5	5.2	GO:1904424	regulation of GTP binding(GO:1904424)
0.5	10.9	GO:0006491	N-glycan processing(GO:0006491)
0.5	1.5	GO:1903237	regulation of leukocyte tethering or rolling(GO:1903236) negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.5	27.8	GO:0043462	regulation of ATPase activity(GO:0043462)
0.5	5.1	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.4	2.2	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.4	13.9	GO:0018345	protein palmitoylation(GO:0018345)
0.4	5.8	GO:0001553	luteinization(GO:0001553)
0.4	4.5	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.4	28.4	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.4	16.0	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.4	13.5	GO:0030593	neutrophil chemotaxis(GO:0030593)
0.4	1.5	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.4	2.3	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.4	29.0	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.4	1.5	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
0.4	8.8	GO:0019835	cytolysis(GO:0019835)
0.4	12.6	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.3	29.6	GO:0007569	cell aging(GO:0007569)
0.3	143.3	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.3	6.3	GO:0030225	macrophage differentiation(GO:0030225)
0.3	5.5	GO:0046415	urate metabolic process(GO:0046415)
0.3	13.2	GO:0034605	cellular response to heat(GO:0034605)
0.3	2.5	GO:0060965	negative regulation of gene silencing by miRNA(GO:0060965)
0.3	6.3	GO:0019068	virion assembly(GO:0019068)
0.3	32.7	GO:0007596	blood coagulation(GO:0007596)
0.3	6.1	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.3	4.5	GO:0046037	GMP metabolic process(GO:0046037)
0.2	5.6	GO:0035455	response to interferon-alpha(GO:0035455)
0.2	10.9	GO:0045638	negative regulation of myeloid cell differentiation(GO:0045638)
0.2	4.1	GO:0097352	autophagosome maturation(GO:0097352)
0.2	10.6	GO:0030101	natural killer cell activation(GO:0030101)
0.2	19.6	GO:0007265	Ras protein signal transduction(GO:0007265)
0.2	1.6	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2	40.6	GO:0071593	leukocyte aggregation(GO:0070486) lymphocyte aggregation(GO:0071593)
0.2	15.4	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2	1.9	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.2	0.8	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.2	8.3	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.2	21.2	GO:0042742	defense response to bacterium(GO:0042742)
0.1	1.3	GO:0060056	mammary gland involution(GO:0060056)
0.1	0.4	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	4.3	GO:0060612	adipose tissue development(GO:0060612)
0.1	0.3	GO:0044857	membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1	10.3	GO:0030100	regulation of endocytosis(GO:0030100)
0.1	0.3	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.1	10.7	GO:0055001	muscle cell development(GO:0055001)
0.1	3.7	GO:0060395	SMAD protein signal transduction(GO:0060395)
0.1	2.5	GO:0051567	histone H3-K9 methylation(GO:0051567)
0.0	4.6	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	5.2	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	1.6	GO:0006284	base-excision repair(GO:0006284)
0.0	3.3	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.3	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	1.0	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.6	116.7	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
13.1	52.6	GO:0019815	B cell receptor complex(GO:0019815)
10.9	32.7	GO:0030690	Noc1p-Noc2p complex(GO:0030690)
9.5	56.8	GO:0031904	endosome lumen(GO:0031904)
7.6	265.6	GO:0001772	immunological synapse(GO:0001772)
7.2	65.2	GO:0042101	T cell receptor complex(GO:0042101)
5.6	33.6	GO:0033093	Weibel-Palade body(GO:0033093)
5.1	55.7	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
4.5	17.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
4.5	17.8	GO:0005606	laminin-1 complex(GO:0005606) laminin-2 complex(GO:0005607) laminin-10 complex(GO:0043259)
4.3	34.2	GO:0005826	actomyosin contractile ring(GO:0005826)
4.1	16.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
4.0	27.8	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
3.6	54.4	GO:0072687	meiotic spindle(GO:0072687)
2.7	42.7	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
2.4	23.6	GO:0043020	NADPH oxidase complex(GO:0043020)
2.3	27.7	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
2.2	8.7	GO:0000444	MIS12/MIND type complex(GO:0000444)
2.0	27.7	GO:0031932	TORC2 complex(GO:0031932)
1.9	24.7	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
1.9	17.0	GO:0070419	nonhomologous end joining complex(GO:0070419)
1.8	63.0	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
1.8	10.7	GO:0016012	sarcoglycan complex(GO:0016012)
1.7	5.2	GO:0071001	U4/U6 snRNP(GO:0071001)
1.7	6.7	GO:0070436	Grb2-EGFR complex(GO:0070436)
1.6	19.4	GO:0071564	npBAF complex(GO:0071564)
1.6	50.2	GO:0008180	COP9 signalosome(GO:0008180)
1.6	14.2	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
1.5	4.5	GO:1902560	GMP reductase complex(GO:1902560)
1.4	19.6	GO:0060091	kinocilium(GO:0060091)
1.4	17.8	GO:0043202	lysosomal lumen(GO:0043202)
1.3	5.3	GO:0031088	platelet dense granule membrane(GO:0031088)
1.2	130.5	GO:0016605	PML body(GO:0016605)
1.2	23.6	GO:0031091	platelet alpha granule(GO:0031091)
1.2	20.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
1.2	338.9	GO:0009897	external side of plasma membrane(GO:0009897)
1.1	42.5	GO:0005771	multivesicular body(GO:0005771)
1.1	27.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
1.0	19.7	GO:0000930	gamma-tubulin complex(GO:0000930)
1.0	6.2	GO:0036396	MIS complex(GO:0036396)
1.0	23.0	GO:0002080	acrosomal membrane(GO:0002080)
1.0	15.7	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
1.0	2.9	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.9	23.0	GO:0005721	pericentric heterochromatin(GO:0005721)
0.9	6.4	GO:0005683	U7 snRNP(GO:0005683)
0.9	19.0	GO:0030057	desmosome(GO:0030057)
0.8	19.3	GO:0045120	pronucleus(GO:0045120)
0.8	23.3	GO:0002102	podosome(GO:0002102)
0.8	6.3	GO:0016282	eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290) eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.8	18.7	GO:0042629	mast cell granule(GO:0042629)
0.8	64.8	GO:0005901	caveola(GO:0005901)
0.7	5.1	GO:0070938	contractile ring(GO:0070938)
0.7	89.3	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.7	10.1	GO:0001891	phagocytic cup(GO:0001891)
0.7	4.8	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.7	75.3	GO:0005884	actin filament(GO:0005884)
0.7	11.9	GO:0019013	viral nucleocapsid(GO:0019013)
0.7	42.9	GO:0031594	neuromuscular junction(GO:0031594)
0.7	13.1	GO:0005922	connexon complex(GO:0005922)
0.6	5.8	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.6	9.3	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.6	42.4	GO:0005811	lipid particle(GO:0005811)
0.6	228.4	GO:0005667	transcription factor complex(GO:0005667)
0.6	18.9	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.6	31.3	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.6	11.7	GO:0005640	nuclear outer membrane(GO:0005640)
0.5	4.0	GO:0005638	lamin filament(GO:0005638)
0.5	2.7	GO:1990393	3M complex(GO:1990393)
0.4	22.6	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.4	9.8	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.4	31.6	GO:0005604	basement membrane(GO:0005604)
0.3	23.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.3	4.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.3	18.1	GO:0031901	early endosome membrane(GO:0031901)
0.3	62.7	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.3	134.7	GO:0009986	cell surface(GO:0009986)
0.3	32.0	GO:0000922	spindle pole(GO:0000922)
0.3	18.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.3	5.6	GO:0032839	dendrite cytoplasm(GO:0032839)
0.3	87.4	GO:0031012	extracellular matrix(GO:0031012)
0.2	1.2	GO:0000322	storage vacuole(GO:0000322)
0.2	6.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.2	0.7	GO:0033186	CAF-1 complex(GO:0033186)
0.2	21.3	GO:0055037	recycling endosome(GO:0055037)
0.2	6.1	GO:0034451	centriolar satellite(GO:0034451)
0.2	11.6	GO:0005776	autophagosome(GO:0005776)
0.2	2.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.2	38.0	GO:0030659	cytoplasmic vesicle membrane(GO:0030659)
0.1	6.8	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.1	19.0	GO:0043235	receptor complex(GO:0043235)
0.1	2.4	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	1.6	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	22.2	GO:0031965	nuclear membrane(GO:0031965)
0.1	0.8	GO:0005796	Golgi lumen(GO:0005796)
0.1	28.4	GO:0016607	nuclear speck(GO:0016607)
0.1	6.2	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	8.5	GO:0001650	fibrillar center(GO:0001650)
0.1	22.7	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.1	3.9	GO:0001726	ruffle(GO:0001726)
0.1	2.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	50.7	GO:0005615	extracellular space(GO:0005615)
0.0	4.5	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.3	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	2.8	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.5	GO:0071013	catalytic step 2 spliceosome(GO:0071013)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
22.7	136.1	GO:0098821	activin receptor activity, type I(GO:0016361) BMP receptor activity(GO:0098821)
13.3	53.1	GO:0042610	CD8 receptor binding(GO:0042610)
12.6	126.3	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
12.3	74.1	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
10.9	32.7	GO:0004911	interleukin-2 receptor activity(GO:0004911)
10.3	30.9	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
9.7	87.7	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
8.2	32.7	GO:0035877	death effector domain binding(GO:0035877)
8.2	24.5	GO:0071791	chemokine (C-C motif) ligand 5 binding(GO:0071791)
8.0	31.9	GO:0051425	inositol bisphosphate phosphatase activity(GO:0016312) PTB domain binding(GO:0051425)
7.9	39.7	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
7.6	45.5	GO:0046624	sphingolipid transporter activity(GO:0046624)
7.5	37.5	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
7.3	21.8	GO:0034040	lipid-transporting ATPase activity(GO:0034040) sterol-transporting ATPase activity(GO:0034041) glycoprotein transporter activity(GO:0034437)
7.0	42.3	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
6.0	36.1	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
5.3	26.4	GO:0004974	leukotriene receptor activity(GO:0004974)
5.1	137.7	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
5.0	90.7	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
5.0	35.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
4.7	14.2	GO:0034211	GTP-dependent protein kinase activity(GO:0034211)
4.5	13.5	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
4.5	35.9	GO:1990430	extracellular matrix protein binding(GO:1990430)
4.3	21.6	GO:0005534	galactose binding(GO:0005534)
4.3	17.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
4.0	36.3	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
3.9	50.5	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
3.8	23.0	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
3.5	24.7	GO:0004111	creatine kinase activity(GO:0004111)
3.5	10.5	GO:0031708	endothelin B receptor binding(GO:0031708)
3.3	13.1	GO:0086077	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
2.7	21.2	GO:0051525	NFAT protein binding(GO:0051525)
2.6	20.8	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
2.5	27.7	GO:0048407	platelet-derived growth factor binding(GO:0048407)
2.4	29.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
2.4	17.0	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
2.4	23.8	GO:0015386	potassium:proton antiporter activity(GO:0015386)
2.4	49.6	GO:0023026	MHC class II protein complex binding(GO:0023026)
2.3	334.2	GO:0017124	SH3 domain binding(GO:0017124)
2.2	48.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
2.1	6.4	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
2.1	6.2	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
2.1	28.8	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
2.0	10.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.9	55.4	GO:0042169	SH2 domain binding(GO:0042169)
1.9	5.6	GO:0019961	interferon binding(GO:0019961)
1.8	19.3	GO:0097157	pre-mRNA intronic binding(GO:0097157)
1.7	72.7	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
1.7	56.8	GO:0022829	wide pore channel activity(GO:0022829)
1.7	10.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
1.7	48.9	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
1.6	19.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
1.6	58.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
1.5	9.3	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
1.5	15.3	GO:0001784	phosphotyrosine binding(GO:0001784)
1.5	4.5	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
1.5	13.3	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.4	58.2	GO:0005504	fatty acid binding(GO:0005504)
1.4	5.6	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.3	19.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
1.3	47.6	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
1.2	3.7	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
1.2	7.3	GO:0050700	CARD domain binding(GO:0050700)
1.2	32.0	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
1.2	44.9	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
1.1	4.5	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.1	8.8	GO:0030274	LIM domain binding(GO:0030274)
1.1	27.2	GO:0004383	guanylate cyclase activity(GO:0004383)
1.1	49.3	GO:0030544	Hsp70 protein binding(GO:0030544)
1.1	64.7	GO:1990782	protein tyrosine kinase binding(GO:1990782)
1.1	25.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
1.0	23.1	GO:0019865	immunoglobulin binding(GO:0019865)
1.0	9.3	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.0	42.7	GO:0004601	peroxidase activity(GO:0004601)
1.0	10.9	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.9	47.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.8	74.2	GO:0019210	kinase inhibitor activity(GO:0019210)
0.8	7.1	GO:0045499	chemorepellent activity(GO:0045499)
0.8	17.3	GO:0005112	Notch binding(GO:0005112)
0.7	28.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.7	47.0	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.7	10.5	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.7	31.8	GO:0017080	sodium channel regulator activity(GO:0017080)
0.7	5.2	GO:0017070	U6 snRNA binding(GO:0017070) U4 snRNA binding(GO:0030621)
0.6	26.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.6	4.8	GO:0035197	siRNA binding(GO:0035197)
0.6	36.6	GO:0005518	collagen binding(GO:0005518)
0.6	4.5	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.6	9.5	GO:0043236	laminin binding(GO:0043236)
0.5	5.5	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.5	43.7	GO:0004713	protein tyrosine kinase activity(GO:0004713)
0.5	1.6	GO:0000703	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.5	5.1	GO:0017166	vinculin binding(GO:0017166)
0.4	17.0	GO:0030551	cyclic nucleotide binding(GO:0030551)
0.4	4.0	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.4	8.8	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.4	29.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.4	13.9	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4	6.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.4	11.9	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.4	4.9	GO:0001968	fibronectin binding(GO:0001968)
0.4	91.6	GO:0005096	GTPase activator activity(GO:0005096)
0.4	16.7	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.4	3.7	GO:0042301	phosphate ion binding(GO:0042301)
0.4	44.2	GO:0008201	heparin binding(GO:0008201)
0.3	6.1	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3	82.3	GO:0030246	carbohydrate binding(GO:0030246)
0.3	226.6	GO:0044212	transcription regulatory region DNA binding(GO:0044212)
0.3	98.3	GO:0005525	GTP binding(GO:0005525)
0.2	6.8	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.2	18.7	GO:0019903	protein phosphatase binding(GO:0019903)
0.2	6.3	GO:0031369	translation initiation factor binding(GO:0031369)
0.2	2.5	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2	15.4	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.1	2.5	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.1	4.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	29.5	GO:0003712	transcription cofactor activity(GO:0003712)
0.1	38.0	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.1	8.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	53.9	GO:0042803	protein homodimerization activity(GO:0042803)
0.1	2.9	GO:0004521	endoribonuclease activity(GO:0004521)
0.1	0.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.3	GO:0050733	RS domain binding(GO:0050733)
0.1	1.5	GO:0008009	chemokine activity(GO:0008009)
0.0	11.5	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.8	GO:0005184	neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.7	115.4	PID S1P S1P4 PATHWAY	S1P4 pathway
6.6	132.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
5.8	99.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
5.8	379.7	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
4.9	157.7	PID ALK1 PATHWAY	ALK1 signaling events
3.7	107.6	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
3.6	39.7	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
3.3	55.7	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
3.2	85.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
3.0	32.7	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
3.0	17.8	PID S1P S1P1 PATHWAY	S1P1 pathway
2.7	30.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
2.7	171.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
2.3	106.7	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
2.2	13.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
2.2	43.7	PID IL23 PATHWAY	IL23-mediated signaling events
2.1	91.7	PID ENDOTHELIN PATHWAY	Endothelins
2.0	36.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
2.0	31.6	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.9	52.6	PID BCR 5PATHWAY	BCR signaling pathway
1.8	31.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
1.7	58.9	PID IL2 1PATHWAY	IL2-mediated signaling events
1.5	52.5	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
1.4	74.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
1.4	31.6	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
1.2	4.9	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
1.2	48.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
1.2	17.8	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
1.1	17.0	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
1.1	24.7	PID EPHB FWD PATHWAY	EPHB forward signaling
1.1	17.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
1.0	36.7	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.0	160.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.0	30.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
1.0	29.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.9	24.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.9	13.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.9	42.8	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.9	21.6	PID INSULIN PATHWAY	Insulin Pathway
0.8	43.3	PID AP1 PATHWAY	AP-1 transcription factor network
0.7	32.1	PID AURORA B PATHWAY	Aurora B signaling
0.7	38.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.7	24.7	PID PLK1 PATHWAY	PLK1 signaling events
0.6	7.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.6	25.5	PID E2F PATHWAY	E2F transcription factor network
0.6	2.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.6	17.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.6	28.5	PID CMYB PATHWAY	C-MYB transcription factor network
0.4	5.6	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.4	71.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.4	6.1	PID RHOA PATHWAY	RhoA signaling pathway
0.4	6.7	PID CDC42 PATHWAY	CDC42 signaling events
0.3	21.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.3	10.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.3	8.4	PID MTOR 4PATHWAY	mTOR signaling pathway
0.2	0.8	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	5.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	35.9	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	1.9	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.4	PID LKB1 PATHWAY	LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.7	205.5	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
5.7	114.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
5.2	78.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
5.0	20.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
4.1	32.7	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
3.9	58.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
3.6	39.7	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
3.3	39.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
3.3	98.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
3.3	16.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
3.3	65.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
3.2	139.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
3.2	48.4	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
2.9	48.7	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
2.9	34.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
2.7	65.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
2.3	339.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
2.3	23.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
2.1	55.7	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
2.1	29.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
2.1	26.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
1.9	26.4	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
1.8	27.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
1.6	46.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
1.6	44.2	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
1.6	85.8	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
1.6	38.9	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
1.5	32.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
1.4	25.8	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
1.4	17.7	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
1.3	21.8	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
1.1	18.5	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
1.1	14.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.9	149.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.9	37.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.9	16.2	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.8	74.3	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.8	69.3	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.7	13.1	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.6	6.4	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.6	36.3	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.5	17.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.5	7.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.4	43.5	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.4	4.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.4	29.2	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.4	30.0	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.3	5.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.3	6.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.3	6.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.3	4.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	8.0	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2	9.3	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.1	5.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	1.6	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	8.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	2.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	1.9	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	9.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	0.8	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	5.6	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation