ISMARA results: En1

Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation

Downloads

Results for En1

Z-value: 1.31

Motif logo

Transcription factors associated with En1

Gene Symbol	Gene ID	Gene Info
En1 NCBI RGD Ensembl	ENSRNOG00000056580	engrailed 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
En1	rn6_v1_chr13_+_36532758_36532758	-0.08	1.6e-01	Click!

Activity profile of En1 motif

Sorted Z-values of En1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_+_54619129 Show fit	53.74	ENSRNOT00000059924	Trat1 NCBI RGD Ensembl Show fit	T cell receptor associated transmembrane adaptor 1
chr8_+_49282460 Show fit	37.85	ENSRNOT00000021488	Cd3d NCBI RGD Ensembl Show fit	CD3d molecule
chr1_-_227441442 Show fit	35.16	ENSRNOT00000028433	Ms4a1 NCBI RGD Ensembl Show fit	membrane spanning 4-domains A1
chr13_-_77896697 Show fit	33.28	ENSRNOT00000003452	Tnn NCBI RGD Ensembl Show fit	tenascin N
chr14_+_38030189 Show fit	29.52	ENSRNOT00000035623	Txk NCBI RGD Ensembl Show fit	TXK tyrosine kinase
chr3_+_16817051 Show fit	29.37	ENSRNOT00000071666	AABR07051550.1 NCBI RGD Ensembl Show fit
chr4_+_69384145 Show fit	28.69	ENSRNOT00000084834	Trbv13-2 NCBI RGD Ensembl Show fit	T cell receptor beta, variable 13-2
chr15_+_32614002 Show fit	27.60	ENSRNOT00000072962	AABR07017902.1 NCBI RGD Ensembl Show fit
chr1_-_226791773 Show fit	26.26	ENSRNOT00000082482 ENSRNOT00000065376 ENSRNOT00000054812 ENSRNOT00000086669	LOC100911215 NCBI RGD Ensembl Show fit	T-cell surface glycoprotein CD5-like
chr3_+_17107861 Show fit	25.91	ENSRNOT00000043097	AABR07051563.1 NCBI RGD Ensembl Show fit

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of En1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
6.7	53.7	GO:0001920	negative regulation of receptor recycling(GO:0001920)
1.4	49.7	GO:0035458	cellular response to interferon-beta(GO:0035458)
3.2	44.7	GO:0045059	positive thymic T cell selection(GO:0045059)
3.0	42.6	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
8.3	33.3	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.3	31.9	GO:0006334	nucleosome assembly(GO:0006334)
7.4	29.5	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
4.1	24.4	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.5	24.1	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
2.6	23.3	GO:0032829	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)

Showing 1 to 10 of 225 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	110.3	GO:0009897	external side of plasma membrane(GO:0009897)
5.1	91.6	GO:0042101	T cell receptor complex(GO:0042101)
0.5	47.5	GO:0000786	nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.6	36.4	GO:0005720	nuclear heterochromatin(GO:0005720)
1.5	24.4	GO:0042581	specific granule(GO:0042581)
1.9	22.5	GO:0005861	troponin complex(GO:0005861)
0.7	22.2	GO:0034451	centriolar satellite(GO:0034451)
1.0	20.4	GO:0005922	connexon complex(GO:0005922)
0.7	19.7	GO:0042588	zymogen granule(GO:0042588)
1.2	19.4	GO:0042613	MHC class II protein complex(GO:0042613)

Showing 1 to 10 of 106 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	49.9	GO:0003735	structural constituent of ribosome(GO:0003735)
1.1	42.8	GO:0042605	peptide antigen binding(GO:0042605)
0.1	39.1	GO:0003924	GTPase activity(GO:0003924)
0.1	37.2	GO:0030246	carbohydrate binding(GO:0030246)
1.7	36.3	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.2	36.2	GO:0003713	transcription coactivator activity(GO:0003713)
0.6	32.5	GO:0005044	scavenger receptor activity(GO:0005044)
0.9	27.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.4	25.2	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	24.8	GO:0042393	histone binding(GO:0042393)

Showing 1 to 10 of 154 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	48.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
1.1	44.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.7	35.9	PID FANCONI PATHWAY	Fanconi anemia pathway
1.0	32.4	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
3.5	24.4	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.4	22.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.4	17.4	PID PLK1 PATHWAY	PLK1 signaling events
0.3	17.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	15.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.3	12.6	PID BCR 5PATHWAY	BCR signaling pathway

Showing 1 to 10 of 47 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
2.4	53.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
4.7	37.8	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.8	31.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
2.4	28.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
1.5	23.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.4	22.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
1.1	20.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.6	19.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.4	17.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3	14.7	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins

Showing 1 to 10 of 73 entries

Results for En1

Z-value: 1.31

Motif logo

Transcription factors associated with En1

Activity-expression correlation:

Activity profile of En1 motif

Sorted Z-values of En1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of En1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: