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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for En1

Z-value: 1.31

Motif logo

Transcription factors associated with En1

Gene Symbol Gene ID Gene Info
ENSRNOG00000056580 engrailed 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
En1rn6_v1_chr13_+_36532758_36532758-0.081.6e-01Click!

Activity profile of En1 motif

Sorted Z-values of En1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_54619129 53.74 ENSRNOT00000059924
T cell receptor associated transmembrane adaptor 1
chr8_+_49282460 37.85 ENSRNOT00000021488
CD3d molecule
chr1_-_227441442 35.16 ENSRNOT00000028433
membrane spanning 4-domains A1
chr13_-_77896697 33.28 ENSRNOT00000003452
tenascin N
chr14_+_38030189 29.52 ENSRNOT00000035623
TXK tyrosine kinase
chr3_+_16817051 29.37 ENSRNOT00000071666

chr4_+_69384145 28.69 ENSRNOT00000084834
T cell receptor beta, variable 13-2
chr15_+_32614002 27.60 ENSRNOT00000072962

chr1_-_226791773 26.26 ENSRNOT00000082482
ENSRNOT00000065376
ENSRNOT00000054812
ENSRNOT00000086669
T-cell surface glycoprotein CD5-like
chr3_+_17107861 25.91 ENSRNOT00000043097

chr10_+_19366793 25.15 ENSRNOT00000050610
family with sequence similarity 196, member B
chr8_-_117932518 24.45 ENSRNOT00000028130
cathelicidin antimicrobial peptide
chrX_-_71168612 23.33 ENSRNOT00000075934
interleukin 2 receptor subunit gamma
chr2_+_223121410 22.71 ENSRNOT00000087559

chr4_+_109467272 22.71 ENSRNOT00000008212
regenerating family member 3 beta
chr1_-_89329185 22.70 ENSRNOT00000078284
CD22 molecule
chr9_+_2202511 22.65 ENSRNOT00000017556
SATB homeobox 1
chrX_+_78372257 22.42 ENSRNOT00000046164
G protein-coupled receptor 174
chr13_-_90022269 22.11 ENSRNOT00000035498
lymphocyte antigen 9
chr3_+_20007192 22.01 ENSRNOT00000075229

chr6_+_139405966 21.78 ENSRNOT00000088974

chrX_+_134979646 21.40 ENSRNOT00000006035
SAM and SH3 domain containing 3
chrX_+_96991658 21.09 ENSRNOT00000049969

chr6_-_138632159 20.86 ENSRNOT00000082921
ENSRNOT00000040702
immunoglobulin heavy constant mu
chr18_+_55466373 20.25 ENSRNOT00000074629
interferon-inducible GTPase 1-like
chr15_+_33271015 19.94 ENSRNOT00000073767
proteasome subunit beta 11
chr15_+_32809069 19.80 ENSRNOT00000070848

chr1_-_100537377 19.63 ENSRNOT00000026599
Spi-B transcription factor
chr20_-_4070721 19.40 ENSRNOT00000000523
RT1 class II, locus Ba
chr1_+_86938138 19.29 ENSRNOT00000075601
coiled-coil glutamate-rich protein 2
chr4_-_103369224 18.50 ENSRNOT00000075709

chr4_-_157750088 17.98 ENSRNOT00000038023
CD27 molecule
chr6_+_139177200 17.86 ENSRNOT00000084131

chr2_-_112802073 17.39 ENSRNOT00000093081
epithelial cell transforming 2
chr4_-_103646906 17.14 ENSRNOT00000047620

chr3_-_16537433 16.41 ENSRNOT00000048523

chr9_-_9675110 16.13 ENSRNOT00000073294
vav guanine nucleotide exchange factor 1
chr18_+_55391388 16.06 ENSRNOT00000071612
interferon-inducible GTPase 1-like
chr4_+_179398621 16.04 ENSRNOT00000049474
ENSRNOT00000067506
lymphoid-restricted membrane protein
chr4_-_164211819 16.02 ENSRNOT00000084796
hypothetical protein LOC497796
chr15_-_37409668 15.96 ENSRNOT00000011742
gap junction protein, beta 6
chr5_+_146294030 15.68 ENSRNOT00000073637

chr4_-_163403653 15.31 ENSRNOT00000088151
killer cell lectin like receptor K1
chr10_+_94566928 15.14 ENSRNOT00000078446
proline rich 29
chr17_-_43807540 14.62 ENSRNOT00000074763
similar to CG31613-PA
chr20_+_7279820 13.98 ENSRNOT00000090820
protein kinase C and casein kinase substrate in neurons 1
chr4_+_101882994 13.94 ENSRNOT00000087773

chr2_+_219628695 13.84 ENSRNOT00000067324
SAS-6 centriolar assembly protein
chr17_+_78764506 13.80 ENSRNOT00000077953
suppressor of variegation 3-9 homolog 2
chr2_-_216348194 13.79 ENSRNOT00000087839
pancreatic alpha-amylase-like
chr6_+_139486775 13.75 ENSRNOT00000077771

chr3_-_148057523 13.68 ENSRNOT00000055408
defensin beta 24
chr3_+_16413080 13.43 ENSRNOT00000040386
Ig kappa chain V19-17-like
chr10_-_67401836 13.18 ENSRNOT00000073071
cytokine receptor-like factor 3
chr20_-_9876008 13.00 ENSRNOT00000001537
trefoil factor 2
chr10_-_89454681 12.96 ENSRNOT00000028109
BRCA1, DNA repair associated
chr6_-_138948583 12.87 ENSRNOT00000084614

chr8_-_122532070 12.81 ENSRNOT00000013705
C-C motif chemokine receptor 4
chr4_-_103115522 12.79 ENSRNOT00000074206

chr18_+_55505993 12.76 ENSRNOT00000043736
similar to interferon-inducible GTPase
chr15_+_32355565 12.76 ENSRNOT00000072382

chr1_+_141120166 12.73 ENSRNOT00000050759
Fanconi anemia, complementation group I
chr17_-_43627629 12.61 ENSRNOT00000022965
histone cluster 1, H2af
chr8_+_96551245 12.57 ENSRNOT00000039850
BCL2-related protein A1
chr13_-_110257367 12.54 ENSRNOT00000005576
denticleless E3 ubiquitin protein ligase homolog
chr17_+_43627930 12.45 ENSRNOT00000081719
histone H2B type 1-N-like
chr3_+_19690016 12.41 ENSRNOT00000085460

chr13_-_74520634 12.41 ENSRNOT00000077169
Ral GEF with PH domain and SH3 binding motif 2
chr6_+_122254841 11.87 ENSRNOT00000005055
G-protein coupled receptor 65
chr15_+_29208606 11.83 ENSRNOT00000073722
ENSRNOT00000086054
uncharacterized LOC100911980
chr6_-_143131118 11.68 ENSRNOT00000074930

chr14_+_76732650 11.50 ENSRNOT00000088197
cytokine-dependent hematopoietic cell linker
chr15_+_31097291 11.47 ENSRNOT00000075456

chr11_+_84745904 11.32 ENSRNOT00000002617
kelch-like family member 6
chr3_-_172537877 11.31 ENSRNOT00000072069
cathepsin Z
chr5_+_68717519 10.91 ENSRNOT00000066226
structural maintenance of chromosomes 2
chr4_-_162025090 10.90 ENSRNOT00000085887
ENSRNOT00000009904
killer cell lectin-like receptor subfamily B, member 1A
chr1_+_215609036 10.72 ENSRNOT00000076187
troponin I2, fast skeletal type
chr3_+_122816924 10.68 ENSRNOT00000045604
similar to ribosomal protein L31
chr18_+_55463308 10.61 ENSRNOT00000073388
interferon-inducible GTPase 1-like
chr4_-_157304653 10.47 ENSRNOT00000051613
leucine rich repeat containing 23
chr6_-_138631997 10.47 ENSRNOT00000073304

chr3_+_18805220 10.41 ENSRNOT00000071216
immunoglobulin kappa variable 4-86
chr15_+_31618297 10.31 ENSRNOT00000072332

chr15_-_29532988 10.26 ENSRNOT00000074782

chr7_+_143629455 10.20 ENSRNOT00000073951
keratin 18
chr16_-_48692476 10.12 ENSRNOT00000013118
interferon regulatory factor 2
chr1_+_7726529 10.02 ENSRNOT00000073460
adenosine deaminase, tRNA-specific 2
chr20_+_3149114 9.95 ENSRNOT00000084770
RT1 class Ib, locus N2
chr18_+_44716226 9.89 ENSRNOT00000086431
TNF alpha induced protein 8
chr7_-_142348232 9.89 ENSRNOT00000078848
polypeptide N-acetylgalactosaminyltransferase 6
chr1_-_169355117 9.88 ENSRNOT00000022992
similar to RIKEN cDNA E030002O03
chr13_-_77821312 9.86 ENSRNOT00000082110

chr2_-_196323881 9.68 ENSRNOT00000028642
TNF alpha induced protein 8 like 2
chr4_-_22192474 9.52 ENSRNOT00000043822
ATP binding cassette subfamily B member 1A
chr7_-_144880092 9.47 ENSRNOT00000055281
nuclear factor, erythroid 2
chr7_+_28654733 9.43 ENSRNOT00000006174
pro-melanin-concentrating hormone
chr15_+_28128078 9.34 ENSRNOT00000082938
ribonuclease pancreatic gamma-type
chr15_-_35394792 9.32 ENSRNOT00000028058
granzyme C
chr10_+_44271587 9.31 ENSRNOT00000047700
tripartite motif-containing 58
chr9_-_60923706 9.17 ENSRNOT00000047517

chr2_-_183128932 9.17 ENSRNOT00000031179
meiotic nuclear divisions 1
chr5_+_56797502 9.16 ENSRNOT00000067992
transmembrane protein 215
chr4_-_78879294 9.08 ENSRNOT00000084543
insulin-like growth factor 2 mRNA binding protein 3
chr20_+_3148665 9.07 ENSRNOT00000086026
RT1 class Ib, locus N2
chr15_+_4209703 9.07 ENSRNOT00000082236
protein phosphatase 3 catalytic subunit beta
chr1_+_226252226 8.98 ENSRNOT00000039369

chr12_-_19314016 8.94 ENSRNOT00000001825
minichromosome maintenance complex component 7
chr3_-_123631109 8.93 ENSRNOT00000091493
sialic acid binding Ig like lectin 1
chr11_+_60383431 8.92 ENSRNOT00000093295
Cd200 molecule
chr1_+_226897625 8.79 ENSRNOT00000029443
solute carrier family 15 member 3
chr10_-_88152064 8.74 ENSRNOT00000019477
keratin 16
chr4_-_131694755 8.61 ENSRNOT00000013271
forkhead box P1
chr2_+_212435728 8.50 ENSRNOT00000046960

chr18_+_25163561 8.47 ENSRNOT00000042287
ENSRNOT00000049898
ENSRNOT00000017573
bridging integrator 1
chr13_-_61070599 8.47 ENSRNOT00000005251
regulator of G-protein signaling 1
chr1_+_72692105 8.45 ENSRNOT00000032439
transmembrane protein 150B
chr6_-_138954741 8.44 ENSRNOT00000083278

chr13_-_31753800 8.44 ENSRNOT00000050715

chr11_-_88038518 8.40 ENSRNOT00000051991
RIMS binding protein 3
chr10_-_90415070 8.39 ENSRNOT00000055179
integrin subunit alpha 2b
chr15_-_24056073 8.38 ENSRNOT00000015100
WD repeat and HMG-box DNA binding protein 1
chr8_-_104155775 8.36 ENSRNOT00000042885
60S ribosomal protein L31-like
chr6_+_139428999 8.32 ENSRNOT00000084482

chr13_-_90839411 8.30 ENSRNOT00000010594
SLAM family member 9
chr11_+_73936750 8.19 ENSRNOT00000002350
ATPase 13A3
chr15_+_87704340 7.92 ENSRNOT00000034987
sciellin
chr15_-_29712639 7.90 ENSRNOT00000073230

chr14_-_18849258 7.84 ENSRNOT00000033406
platelet factor 4
chr7_-_96464049 7.81 ENSRNOT00000006517
hyaluronan synthase 2
chr5_-_78393143 7.75 ENSRNOT00000043610
60S ribosomal protein L31-like
chr9_-_61418679 7.74 ENSRNOT00000078800
ankyrin repeat domain 44
chr3_+_58022238 7.66 ENSRNOT00000002085
histone acetyltransferase 1
chr13_-_53137253 7.61 ENSRNOT00000011368
G protein-coupled receptor 25
chrX_-_156891038 7.56 ENSRNOT00000091495
arginine vasopressin receptor 2
chr11_+_47146308 7.55 ENSRNOT00000002191
centrosomal protein 97
chr20_-_5076539 7.49 ENSRNOT00000076253
ENSRNOT00000037613
lymphocyte antigen 6 complex, locus G6F
chr4_+_145489869 7.48 ENSRNOT00000082618
Fanconi anemia, complementation group D2
chr6_-_124876710 7.35 ENSRNOT00000073530
G protein-coupled receptor 68
chr4_+_78320190 7.34 ENSRNOT00000032742
ENSRNOT00000091359
GTPase, IMAP family member 4
chr5_-_153924896 7.29 ENSRNOT00000065247
grainyhead-like transcription factor 3
chr4_+_156051915 7.29 ENSRNOT00000087933
ENSRNOT00000077840
C-type lectin domain family 4, member A
chr4_+_102290338 7.22 ENSRNOT00000011067

chr13_+_92136290 7.21 ENSRNOT00000049819
olfactory receptor 1587
chr11_+_85633243 7.10 ENSRNOT00000045807
Ig lambda chain V-VI region AR-like
chrX_-_156891213 7.10 ENSRNOT00000082899
arginine vasopressin receptor 2
chr8_-_21492801 7.10 ENSRNOT00000077465
zinc finger protein 426
chr5_+_90818736 7.09 ENSRNOT00000093480
ENSRNOT00000009083
lysine demethylase 4C
chr1_+_212695735 7.02 ENSRNOT00000049269
CD163 molecule-like 1
chr10_+_29165577 7.01 ENSRNOT00000078415
cyclin J-like
chr7_+_14643704 6.99 ENSRNOT00000044642

chr3_-_161246351 6.95 ENSRNOT00000020348
troponin C2, fast skeletal type
chr5_+_131915382 6.88 ENSRNOT00000087012
selection and upkeep of intraepithelial T cells 1
chr5_-_83648044 6.84 ENSRNOT00000046725
similar to ribosomal protein L31
chr16_-_54137660 6.81 ENSRNOT00000085435
pericentriolar material 1
chrX_-_115426083 6.76 ENSRNOT00000014756

chr5_+_139007642 6.69 ENSRNOT00000066774
human immunodeficiency virus type I enhancer binding protein 3
chr13_-_89306219 6.66 ENSRNOT00000004183
ENSRNOT00000079247
Fc receptor-like A
chr7_-_2961873 6.63 ENSRNOT00000067441
ribosomal protein S15, pseudogene 2
chr2_+_198040536 6.60 ENSRNOT00000028744
acidic nuclear phosphoprotein 32 family member E
chr6_+_127927650 6.56 ENSRNOT00000057271
serine protease inhibitor A3F-like
chr3_+_79498179 6.50 ENSRNOT00000030750
nucleoporin 160
chr4_+_45567573 6.46 ENSRNOT00000089824
ankyrin repeat domain 7
chr4_+_71652354 6.41 ENSRNOT00000022672
ENSRNOT00000022543
caspase 2
chr18_-_32670665 6.40 ENSRNOT00000019409
nuclear receptor subfamily 3, group C, member 1
chr3_+_103753238 6.36 ENSRNOT00000007144
solute carrier family 12, member 6
chr8_+_52729003 6.35 ENSRNOT00000081738
neurexophilin and PC-esterase domain family, member 4
chr8_+_22050222 6.27 ENSRNOT00000028096
intercellular adhesion molecule 5
chr6_-_125317593 6.10 ENSRNOT00000074142
ovarian cancer G-protein coupled receptor 1-like
chr10_-_34242985 6.06 ENSRNOT00000046438
similar to novel protein
chrX_-_1346181 6.04 ENSRNOT00000042736
60S ribosomal protein L12-like
chr9_-_46309451 6.01 ENSRNOT00000018684
ring finger protein 149
chr7_-_59763219 5.98 ENSRNOT00000041210
similar to 60S ribosomal protein L12
chr10_+_43817947 5.98 ENSRNOT00000032816
LY6/PLAUR domain containing 8
chr15_-_52399074 5.90 ENSRNOT00000018440
exportin 7
chr17_+_15429708 5.88 ENSRNOT00000093261
hypothetical protein LOC679342
chr6_-_143768985 5.87 ENSRNOT00000046694
immunoglobulin heavy variable V15-2
chr10_+_71008709 5.86 ENSRNOT00000055923
WAP four-disulfide core domain 18
chr4_+_31704747 5.83 ENSRNOT00000047850

chr10_-_82399484 5.76 ENSRNOT00000082972
ENSRNOT00000055582
xylosyltransferase 2
chr4_+_183896303 5.73 ENSRNOT00000055437
similar to hypothetical protein FLJ10652
chr7_+_27081667 5.60 ENSRNOT00000066143
nuclear transcription factor Y subunit beta
chr9_-_73948583 5.58 ENSRNOT00000018097
myosin, light chain 1
chr14_+_104821215 5.58 ENSRNOT00000007162
SERTA domain containing 2
chr15_-_51834030 5.54 ENSRNOT00000024895
cell cycle and apoptosis regulator 2
chr10_-_53595827 5.53 ENSRNOT00000004560
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
chr4_+_9882904 5.53 ENSRNOT00000016909
DnaJ heat shock protein family (Hsp40) member C2
chr10_+_104019888 5.49 ENSRNOT00000032016
solute carrier family 16 member 5
chr12_+_2948570 5.46 ENSRNOT00000071450
hypothetical LOC100363914
chr14_+_96300596 5.44 ENSRNOT00000071967
similar to Spindlin-like protein 2 (SPIN-2)
chr9_+_81656116 5.43 ENSRNOT00000083421
solute carrier family 11 member 1
chr15_-_82581916 5.43 ENSRNOT00000057891
similar to ribosomal protein L27
chr1_-_116567189 5.42 ENSRNOT00000048996
protein BEX1-like
chr5_-_120083904 5.37 ENSRNOT00000064542
Janus kinase 1
chr4_+_98027554 5.37 ENSRNOT00000009503
Serpine1 mRNA binding protein 1
chr4_-_183417667 5.36 ENSRNOT00000089160
family with sequence similarity 60, member A
chr10_+_14122878 5.31 ENSRNOT00000052008
heparan sulfate-glucosamine 3-sulfotransferase 6
chr5_-_138361702 5.27 ENSRNOT00000067943
ENSRNOT00000064712
peptidylprolyl isomerase H
chr10_-_49192693 5.26 ENSRNOT00000004294
zinc finger protein 286A
chr20_-_44255064 5.16 ENSRNOT00000000735
WNT1 inducible signaling pathway protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of En1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.3 33.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
7.4 29.5 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
6.7 53.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
5.7 22.7 GO:1903576 response to L-arginine(GO:1903576)
5.1 15.3 GO:2000502 stimulatory C-type lectin receptor signaling pathway(GO:0002223) negative regulation of natural killer cell chemotaxis(GO:2000502)
4.5 9.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
4.3 13.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
4.1 24.4 GO:0071224 cellular response to peptidoglycan(GO:0071224)
3.2 44.7 GO:0045059 positive thymic T cell selection(GO:0045059)
3.1 12.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
3.0 42.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
2.9 8.6 GO:0061470 T follicular helper cell differentiation(GO:0061470)
2.8 8.5 GO:0060988 lipid tube assembly(GO:0060988)
2.6 23.3 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
2.4 14.7 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
2.4 21.9 GO:0043031 negative regulation of macrophage activation(GO:0043031)
2.4 9.5 GO:1905231 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) response to cyclosporin A(GO:1905237) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
2.2 22.1 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
2.2 10.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.1 6.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
2.0 7.8 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
2.0 7.8 GO:1900623 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) positive regulation of hyaluronan biosynthetic process(GO:1900127) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.9 9.4 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.8 7.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
1.8 5.4 GO:0055073 cadmium ion homeostasis(GO:0055073)
1.8 10.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
1.8 5.3 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
1.7 13.8 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
1.6 21.4 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
1.6 11.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
1.6 11.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
1.6 6.4 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
1.6 9.5 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
1.6 4.7 GO:2000769 regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771)
1.5 7.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.5 8.8 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
1.4 5.8 GO:0030210 heparin biosynthetic process(GO:0030210)
1.4 8.4 GO:0070827 chromatin maintenance(GO:0070827)
1.4 49.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
1.4 21.9 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
1.3 5.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.3 8.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.2 6.1 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616)
1.2 4.8 GO:0072144 glomerular mesangial cell development(GO:0072144)
1.1 19.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
1.1 3.3 GO:1990743 protein sialylation(GO:1990743)
1.1 17.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.1 3.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.0 14.0 GO:0019985 translesion synthesis(GO:0019985)
1.0 1.0 GO:0051012 microtubule sliding(GO:0051012)
0.9 4.6 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.9 3.6 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.9 2.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.9 7.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.8 11.3 GO:0002467 germinal center formation(GO:0002467)
0.8 3.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240) detection of muscle stretch(GO:0035995)
0.8 4.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.8 7.7 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.7 8.5 GO:0001554 luteolysis(GO:0001554)
0.7 5.5 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.7 2.1 GO:0010813 neuropeptide catabolic process(GO:0010813)
0.7 2.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.7 7.4 GO:0010755 regulation of plasminogen activation(GO:0010755) positive regulation of plasminogen activation(GO:0010756)
0.7 4.0 GO:0050917 sensory perception of umami taste(GO:0050917)
0.7 9.9 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.7 3.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.6 17.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.6 3.2 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.6 1.8 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.6 8.9 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.6 3.0 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.6 8.7 GO:0051546 keratinocyte migration(GO:0051546)
0.6 12.8 GO:0002507 tolerance induction(GO:0002507)
0.6 1.2 GO:1903660 negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.6 4.5 GO:0009405 pathogenesis(GO:0009405)
0.6 6.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.5 24.1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.5 1.6 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.5 1.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.5 1.6 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.5 15.8 GO:0030225 macrophage differentiation(GO:0030225)
0.5 10.2 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.5 3.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.5 7.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.5 2.0 GO:0097327 response to antineoplastic agent(GO:0097327)
0.5 3.8 GO:0060591 chondroblast differentiation(GO:0060591)
0.5 19.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.5 3.3 GO:0015705 iodide transport(GO:0015705)
0.5 22.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.5 1.4 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.5 2.7 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.4 8.9 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.4 2.7 GO:0045072 regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.4 3.4 GO:0015808 L-alanine transport(GO:0015808)
0.4 3.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.4 1.3 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.4 4.4 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.4 13.2 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.4 1.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.4 1.6 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.4 3.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.4 13.8 GO:0007099 centriole replication(GO:0007099)
0.4 2.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 13.2 GO:0043029 T cell homeostasis(GO:0043029)
0.4 4.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.4 0.7 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.4 0.7 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.3 6.6 GO:0043486 histone exchange(GO:0043486)
0.3 2.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3 8.7 GO:0010447 response to acidic pH(GO:0010447)
0.3 31.9 GO:0006334 nucleosome assembly(GO:0006334)
0.3 1.6 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.3 3.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.3 3.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.3 0.9 GO:0048749 compound eye development(GO:0048749)
0.3 2.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.3 1.8 GO:0043587 tongue morphogenesis(GO:0043587)
0.3 8.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 0.9 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.3 4.9 GO:1990845 adaptive thermogenesis(GO:1990845)
0.3 1.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.3 5.9 GO:0097320 membrane tubulation(GO:0097320)
0.3 2.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 4.0 GO:0010543 regulation of platelet activation(GO:0010543)
0.3 0.8 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.3 2.4 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.3 2.6 GO:0016926 protein desumoylation(GO:0016926)
0.3 1.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 1.5 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.3 1.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.2 6.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 4.5 GO:0046415 urate metabolic process(GO:0046415)
0.2 3.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 1.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 2.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 9.9 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.2 1.6 GO:0007341 penetration of zona pellucida(GO:0007341)
0.2 0.4 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.2 2.8 GO:0060013 righting reflex(GO:0060013)
0.2 4.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 16.0 GO:0051602 response to electrical stimulus(GO:0051602)
0.2 2.8 GO:0015671 oxygen transport(GO:0015671)
0.2 1.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 1.0 GO:0070889 platelet alpha granule organization(GO:0070889)
0.2 2.0 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.2 1.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.2 7.6 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.2 8.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 2.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.2 3.6 GO:0098743 cell aggregation(GO:0098743)
0.2 1.1 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.2 0.9 GO:0044650 virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650) receptor-mediated virion attachment to host cell(GO:0046813)
0.2 10.9 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2 12.4 GO:0006342 chromatin silencing(GO:0006342)
0.2 1.5 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.2 0.7 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 1.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.2 2.7 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 1.9 GO:0048733 sebaceous gland development(GO:0048733)
0.2 1.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 0.6 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.2 5.5 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.1 9.7 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.1 1.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 8.6 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.7 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 0.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 2.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 2.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 3.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.5 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 2.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 6.1 GO:0042100 B cell proliferation(GO:0042100)
0.1 2.5 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 6.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 5.0 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 2.0 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 4.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 5.9 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 3.4 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.4 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 3.1 GO:0031641 regulation of myelination(GO:0031641)
0.1 9.0 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 1.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 1.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 1.8 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.2 GO:0072126 positive regulation of glomerular mesangial cell proliferation(GO:0072126) positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0006863 purine nucleobase transport(GO:0006863) nucleobase transport(GO:0015851)
0.1 6.0 GO:0035690 cellular response to drug(GO:0035690)
0.1 0.5 GO:0033683 UV protection(GO:0009650) nucleotide-excision repair, DNA incision(GO:0033683)
0.1 2.2 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 4.6 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.1 4.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 2.7 GO:0007032 endosome organization(GO:0007032)
0.1 1.2 GO:0030261 chromosome condensation(GO:0030261)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.8 GO:0043030 regulation of macrophage activation(GO:0043030)
0.1 1.1 GO:0008033 tRNA processing(GO:0008033)
0.1 8.1 GO:0051607 defense response to virus(GO:0051607)
0.1 2.9 GO:0006611 protein export from nucleus(GO:0006611)
0.1 6.1 GO:0006909 phagocytosis(GO:0006909)
0.1 1.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 6.4 GO:0021987 cerebral cortex development(GO:0021987)
0.1 1.4 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857)
0.1 5.5 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.9 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 2.5 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 1.5 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 1.0 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 7.1 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.7 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.7 GO:0006400 tRNA modification(GO:0006400)
0.0 1.5 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 14.0 GO:0006412 translation(GO:0006412)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 2.0 GO:0009411 response to UV(GO:0009411)
0.0 0.3 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.8 GO:0021510 spinal cord development(GO:0021510)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 91.6 GO:0042101 T cell receptor complex(GO:0042101)
4.3 17.4 GO:0097149 centralspindlin complex(GO:0097149)
3.2 13.0 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
2.8 13.8 GO:0098536 deuterosome(GO:0098536)
2.5 12.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.0 7.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.9 22.5 GO:0005861 troponin complex(GO:0005861)
1.8 5.5 GO:0044609 DBIRD complex(GO:0044609)
1.8 5.4 GO:0070821 tertiary granule membrane(GO:0070821)
1.8 5.3 GO:0071001 U4/U6 snRNP(GO:0071001)
1.5 24.4 GO:0042581 specific granule(GO:0042581)
1.5 9.1 GO:0005955 calcineurin complex(GO:0005955)
1.4 10.9 GO:0000796 condensin complex(GO:0000796)
1.2 19.4 GO:0042613 MHC class II protein complex(GO:0042613)
1.2 7.1 GO:0097255 R2TP complex(GO:0097255)
1.2 4.6 GO:1990005 granular vesicle(GO:1990005)
1.0 20.4 GO:0005922 connexon complex(GO:0005922)
1.0 4.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.9 3.7 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.9 11.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.8 8.9 GO:0042555 MCM complex(GO:0042555)
0.8 19.3 GO:0005839 proteasome core complex(GO:0005839)
0.8 5.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.8 8.4 GO:0002177 manchette(GO:0002177)
0.7 3.0 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.7 6.6 GO:0000812 Swr1 complex(GO:0000812)
0.7 22.2 GO:0034451 centriolar satellite(GO:0034451)
0.7 19.7 GO:0042588 zymogen granule(GO:0042588)
0.7 9.5 GO:0016580 Sin3 complex(GO:0016580)
0.7 2.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.6 36.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.6 7.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.6 6.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.6 14.0 GO:0030137 COPI-coated vesicle(GO:0030137)
0.5 2.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.5 47.5 GO:0000786 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.5 2.5 GO:0042587 glycogen granule(GO:0042587)
0.4 2.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.4 5.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 4.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 1.8 GO:1990769 proximal neuron projection(GO:1990769)
0.4 7.8 GO:0031091 platelet alpha granule(GO:0031091)
0.4 1.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 1.4 GO:0044194 cytolytic granule(GO:0044194)
0.3 110.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.3 1.2 GO:0097451 glial limiting end-foot(GO:0097451)
0.3 2.2 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.3 7.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 3.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 1.6 GO:0030896 checkpoint clamp complex(GO:0030896)
0.3 2.8 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.3 1.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.2 3.5 GO:0060091 kinocilium(GO:0060091)
0.2 2.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 1.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 1.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 18.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.2 GO:0070449 elongin complex(GO:0070449)
0.2 2.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 1.2 GO:0030870 Mre11 complex(GO:0030870)
0.2 4.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 8.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 17.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 12.2 GO:0016605 PML body(GO:0016605)
0.1 9.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 2.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 3.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 9.7 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 1.9 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.8 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 7.5 GO:0045095 keratin filament(GO:0045095)
0.1 4.1 GO:0099738 cell cortex region(GO:0099738)
0.1 0.7 GO:0042825 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.1 1.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 6.1 GO:0005882 intermediate filament(GO:0005882)
0.1 5.3 GO:0005643 nuclear pore(GO:0005643)
0.1 6.9 GO:0000793 condensed chromosome(GO:0000793)
0.1 4.9 GO:0000502 proteasome complex(GO:0000502)
0.1 2.0 GO:0002080 acrosomal membrane(GO:0002080)
0.1 3.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.6 GO:0016235 aggresome(GO:0016235)
0.1 0.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.4 GO:0042629 mast cell granule(GO:0042629)
0.1 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.1 6.6 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 8.0 GO:0005840 ribosome(GO:0005840)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 12.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 2.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0044447 axoneme part(GO:0044447)
0.0 1.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 2.3 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.8 GO:0004556 alpha-amylase activity(GO:0004556)
4.3 12.8 GO:0004522 ribonuclease A activity(GO:0004522)
3.9 23.3 GO:0019976 interleukin-2 binding(GO:0019976)
2.9 8.8 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
2.3 9.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
2.2 15.6 GO:0031014 troponin T binding(GO:0031014)
2.0 13.8 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
1.9 5.8 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.9 9.5 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
1.8 5.3 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
1.7 36.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
1.6 6.4 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
1.6 7.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.6 7.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.4 13.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
1.4 22.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
1.4 8.4 GO:0070051 fibrinogen binding(GO:0070051)
1.3 14.7 GO:0005000 vasopressin receptor activity(GO:0005000)
1.3 7.8 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.2 7.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
1.2 4.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.1 20.2 GO:0070182 DNA polymerase binding(GO:0070182)
1.1 5.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
1.1 5.4 GO:0005131 growth hormone receptor binding(GO:0005131)
1.1 42.8 GO:0042605 peptide antigen binding(GO:0042605)
1.0 6.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
1.0 5.1 GO:0070513 death domain binding(GO:0070513)
1.0 12.6 GO:0051400 BH domain binding(GO:0051400)
0.9 4.6 GO:0001729 ceramide kinase activity(GO:0001729)
0.9 27.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.9 9.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.9 4.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.9 5.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.9 12.8 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.8 5.0 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.8 4.1 GO:0015616 DNA translocase activity(GO:0015616)
0.8 3.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.8 4.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.8 4.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.8 15.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.8 16.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.8 3.1 GO:0004645 phosphorylase activity(GO:0004645)
0.7 5.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.7 19.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.7 3.4 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.7 2.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.6 6.4 GO:1990239 steroid hormone binding(GO:1990239)
0.6 3.2 GO:0051373 FATZ binding(GO:0051373)
0.6 32.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.6 2.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.6 12.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.6 5.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.5 5.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.5 21.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.5 4.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 6.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.5 2.0 GO:0019770 IgG receptor activity(GO:0019770)
0.5 1.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.5 9.1 GO:0048156 tau protein binding(GO:0048156)
0.5 10.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.5 1.4 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.5 4.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.4 3.6 GO:0004966 galanin receptor activity(GO:0004966)
0.4 15.7 GO:0050681 androgen receptor binding(GO:0050681)
0.4 3.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.4 25.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.4 2.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.4 1.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.4 4.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 5.0 GO:0005522 profilin binding(GO:0005522)
0.4 2.6 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.4 0.7 GO:0046978 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.3 6.9 GO:0005537 mannose binding(GO:0005537)
0.3 2.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.3 6.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.3 9.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 4.4 GO:0005243 gap junction channel activity(GO:0005243)
0.3 13.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.3 2.7 GO:0008432 JUN kinase binding(GO:0008432)
0.3 2.1 GO:0003720 double-stranded telomeric DNA binding(GO:0003691) telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.3 2.1 GO:0001595 angiotensin receptor activity(GO:0001595)
0.3 8.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.3 2.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.3 1.7 GO:1901612 cardiolipin binding(GO:1901612)
0.3 5.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 2.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 24.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 8.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.2 GO:0034235 GPI anchor binding(GO:0034235)
0.2 7.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 2.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 0.4 GO:0097677 STAT family protein binding(GO:0097677)
0.2 13.0 GO:0003684 damaged DNA binding(GO:0003684)
0.2 4.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 5.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 1.0 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.2 49.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 2.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 2.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 1.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 3.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 36.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.2 7.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 3.0 GO:0001968 fibronectin binding(GO:0001968)
0.1 11.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 13.5 GO:0005178 integrin binding(GO:0005178)
0.1 1.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 39.1 GO:0003924 GTPase activity(GO:0003924)
0.1 24.8 GO:0042393 histone binding(GO:0042393)
0.1 37.2 GO:0030246 carbohydrate binding(GO:0030246)
0.1 1.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.0 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 2.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 4.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 10.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 2.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 2.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 6.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 2.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 17.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 7.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 10.9 GO:0005525 GTP binding(GO:0005525)
0.1 2.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 1.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.7 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 2.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 3.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 2.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.1 3.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.6 GO:0008061 chitin binding(GO:0008061)
0.1 2.2 GO:0015485 cholesterol binding(GO:0015485)
0.1 2.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 3.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 2.1 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0015216 purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.5 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0004950 chemokine receptor activity(GO:0004950)
0.0 2.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.2 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 24.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
1.3 48.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
1.1 44.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
1.0 32.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.7 35.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.5 4.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.4 22.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.4 4.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.4 17.4 PID PLK1 PATHWAY PLK1 signaling events
0.3 8.9 PID ATR PATHWAY ATR signaling pathway
0.3 5.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 11.1 PID ARF6 PATHWAY Arf6 signaling events
0.3 17.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 12.6 PID BCR 5PATHWAY BCR signaling pathway
0.3 1.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.3 6.0 PID EPO PATHWAY EPO signaling pathway
0.3 9.4 PID AURORA B PATHWAY Aurora B signaling
0.3 3.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 7.4 PID MYC PATHWAY C-MYC pathway
0.2 7.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 8.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 4.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.2 3.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 2.7 PID IL27 PATHWAY IL27-mediated signaling events
0.2 4.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 4.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 4.1 PID P73PATHWAY p73 transcription factor network
0.2 6.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 2.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 9.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 7.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.2 PID FOXO PATHWAY FoxO family signaling
0.1 5.9 PID E2F PATHWAY E2F transcription factor network
0.1 2.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 3.7 PID FGF PATHWAY FGF signaling pathway
0.1 15.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 2.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.7 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 37.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
2.4 53.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
2.4 28.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
1.5 23.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
1.2 12.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.1 20.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.9 14.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.8 8.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.8 31.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.7 4.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.7 2.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.7 2.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.6 19.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5 10.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.5 11.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.4 22.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 4.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.4 7.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.4 4.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.4 17.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4 3.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 6.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.4 6.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.3 3.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 3.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 7.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 4.8 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.3 3.8 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.3 4.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 14.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.3 6.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.3 4.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.3 13.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.3 1.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 4.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 4.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 3.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 7.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 5.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 2.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 2.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 2.8 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 5.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 1.9 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.2 1.5 REACTOME OPSINS Genes involved in Opsins
0.2 11.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 10.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 2.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 4.0 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.1 2.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 5.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 12.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.9 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 3.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 5.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 7.4 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.8 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 1.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex