ISMARA results: Elf1_Elf2_Etv2

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Elf1_Elf2_Etv2_Elf4

Z-value: 4.14

Motif logo

Transcription factors associated with Elf1_Elf2_Etv2_Elf4

Gene Symbol	Gene ID	Gene Info
Elf1 NCBI RGD Ensembl	ENSRNOG00000011762	E74-like factor 1
Elf2 NCBI RGD Ensembl	ENSRNOG00000010815	E74-like factor 2
Etv2 NCBI RGD Ensembl	ENSRNOG00000024288	ets variant 2
Elf4 NCBI RGD Ensembl	ENSRNOG00000005352	E74 like ETS transcription factor 4

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Elf1	rn6_v1_chr15_+_61826711_61826711	0.91	3.6e-125	Click!
Elf4	rn6_v1_chrX_-_135250519_135250519	0.74	4.0e-57	Click!
Elf2	rn6_v1_chr2_-_140334912_140334912	0.54	3.3e-25	Click!
Etv2	rn6_v1_chr1_-_89094530_89094530	-0.07	1.9e-01	Click!

Activity profile of Elf1_Elf2_Etv2_Elf4 motif

Sorted Z-values of Elf1_Elf2_Etv2_Elf4 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr13_+_89774764 Show fit	208.40	ENSRNOT00000005619	Arhgap30 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 30
chr1_+_198744050 Show fit	182.17	ENSRNOT00000024404	Itgal NCBI RGD Ensembl Show fit	integrin subunit alpha L
chr13_+_50164563 Show fit	170.25	ENSRNOT00000029533	Lax1 NCBI RGD Ensembl Show fit	lymphocyte transmembrane adaptor 1
chr5_-_58987760 Show fit	154.58	ENSRNOT00000035040	Sit1 NCBI RGD Ensembl Show fit	signaling threshold regulating transmembrane adaptor 1
chr10_+_39875371 Show fit	139.70	ENSRNOT00000013481	Rapgef6 NCBI RGD Ensembl Show fit	Rap guanine nucleotide exchange factor 6
chrX_-_71169038 Show fit	134.59	ENSRNOT00000005343	Il2rg NCBI RGD Ensembl Show fit	interleukin 2 receptor subunit gamma
chr4_+_157523320 Show fit	132.61	ENSRNOT00000023192	Zfp384 NCBI RGD Ensembl Show fit	zinc finger protein 384
chr5_+_154522119 Show fit	131.13	ENSRNOT00000072618	E2f2 NCBI RGD Ensembl Show fit	E2F transcription factor 2
chr7_-_107392972 Show fit	126.00	ENSRNOT00000093425	Tmem71 NCBI RGD Ensembl Show fit	transmembrane protein 71
chr13_-_90022269 Show fit	124.21	ENSRNOT00000035498	Ly9 NCBI RGD Ensembl Show fit	lymphocyte antigen 9
chr10_+_11810926 Show fit	120.38	ENSRNOT00000036205 ENSRNOT00000036189	Nlrc3 NCBI RGD Ensembl Show fit	NLR family, CARD domain containing 3
chr10_+_47930633 Show fit	119.93	ENSRNOT00000003515	Grap NCBI RGD Ensembl Show fit	GRB2-related adaptor protein
chr20_+_9948908 Show fit	108.65	ENSRNOT00000001541	Ubash3a NCBI RGD Ensembl Show fit	ubiquitin associated and SH3 domain containing, A
chr20_+_5441876 Show fit	107.24	ENSRNOT00000092476	Rps18 NCBI RGD Ensembl Show fit	ribosomal protein S18
chr11_+_84745904 Show fit	107.11	ENSRNOT00000002617	Klhl6 NCBI RGD Ensembl Show fit	kelch-like family member 6
chr1_+_221448661 Show fit	106.24	ENSRNOT00000072493	LOC100910252 NCBI RGD Ensembl Show fit	sororin-like
chr2_+_209097927 Show fit	105.04	ENSRNOT00000023807	Dennd2d NCBI RGD Ensembl Show fit	DENN domain containing 2D
chr20_+_5509059 Show fit	104.11	ENSRNOT00000065349	Kifc1 NCBI RGD Ensembl Show fit	kinesin family member C1
chr5_-_79222687 Show fit	103.01	ENSRNOT00000010516	Akna NCBI RGD Ensembl Show fit	AT-hook transcription factor
chr1_+_198528635 Show fit	100.85	ENSRNOT00000022765	LOC308990 NCBI RGD Ensembl Show fit	hypothetical protein LOC308990
chr10_+_59529785 Show fit	100.03	ENSRNOT00000064840 ENSRNOT00000065181	Atp2a3 NCBI RGD Ensembl Show fit	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr3_-_160730360 Show fit	99.85	ENSRNOT00000075864	RGD1563818 NCBI RGD Ensembl Show fit	similar to secretory leukocyte protease inhibitor
chr13_-_55173692 Show fit	99.34	ENSRNOT00000064785 ENSRNOT00000029878 ENSRNOT00000029865 ENSRNOT00000060292 ENSRNOT00000000814	Ptprc NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type, C
chr20_+_30915213 Show fit	98.65	ENSRNOT00000000681	Prf1 NCBI RGD Ensembl Show fit	perforin 1
chr2_-_190100276 Show fit	98.35	ENSRNOT00000015351	S100a9 NCBI RGD Ensembl Show fit	S100 calcium binding protein A9
chr4_+_34282625 Show fit	98.26	ENSRNOT00000011138 ENSRNOT00000086735	Glcci1 NCBI RGD Ensembl Show fit	glucocorticoid induced 1
chr3_-_160802433 Show fit	97.82	ENSRNOT00000076191	Slpi NCBI RGD Ensembl Show fit	secretory leukocyte peptidase inhibitor
chr1_-_198476476 Show fit	97.52	ENSRNOT00000027525	Kif22 NCBI RGD Ensembl Show fit	kinesin family member 22
chr4_+_157523110 Show fit	96.44	ENSRNOT00000081640	Zfp384 NCBI RGD Ensembl Show fit	zinc finger protein 384
chr15_-_51834030 Show fit	96.17	ENSRNOT00000024895	Ccar2 NCBI RGD Ensembl Show fit	cell cycle and apoptosis regulator 2
chr8_-_49308806 Show fit	94.37	ENSRNOT00000047291	Cd3e NCBI RGD Ensembl Show fit	CD3e molecule
chr1_+_215628785 Show fit	93.95	ENSRNOT00000054864	Lsp1 NCBI RGD Ensembl Show fit	lymphocyte-specific protein 1
chr15_+_45422010 Show fit	93.50	ENSRNOT00000012231	Rnaseh2b NCBI RGD Ensembl Show fit	ribonuclease H2, subunit B
chr14_+_44889287 Show fit	93.08	ENSRNOT00000091312 ENSRNOT00000032273	Tmem156 NCBI RGD Ensembl Show fit	transmembrane protein 156
chrX_+_15155230 Show fit	91.84	ENSRNOT00000073289 ENSRNOT00000051439	Was NCBI RGD Ensembl Show fit	Wiskott-Aldrich syndrome
chr13_-_111917587 Show fit	91.22	ENSRNOT00000007649	Traf3ip3 NCBI RGD Ensembl Show fit	TRAF3 interacting protein 3
chr5_-_140585408 Show fit	90.46	ENSRNOT00000018711	Cap1 NCBI RGD Ensembl Show fit	adenylate cyclase associated protein 1
chr5_+_173460354 Show fit	90.11	ENSRNOT00000038747	Tnfrsf18 NCBI RGD Ensembl Show fit	TNF receptor superfamily member 18
chr3_+_119776925 Show fit	89.97	ENSRNOT00000018549	Dusp2 NCBI RGD Ensembl Show fit	dual specificity phosphatase 2
chrX_+_29157470 Show fit	89.67	ENSRNOT00000081986	LOC100910245 NCBI RGD Ensembl Show fit	ribose-phosphate pyrophosphokinase 2-like
chr1_-_197770669 Show fit	88.98	ENSRNOT00000023563	Lat NCBI RGD Ensembl Show fit	linker for activation of T cells
chr3_+_16610086 Show fit	88.92	ENSRNOT00000046231	LOC100361009 NCBI RGD Ensembl Show fit	rCG64257-like
chr7_+_120125633 Show fit	88.56	ENSRNOT00000012480	Sh3bp1 NCBI RGD Ensembl Show fit	SH3-domain binding protein 1
chr9_-_9985358 Show fit	88.49	ENSRNOT00000080856	Crb3 NCBI RGD Ensembl Show fit	crumbs 3, cell polarity complex component
chr4_+_149957206 Show fit	87.30	ENSRNOT00000083843	Hnrnpf NCBI RGD Ensembl Show fit	heterogeneous nuclear ribonucleoprotein F
chr17_+_43791657 Show fit	87.23	ENSRNOT00000074024	Hist2h3c2 NCBI RGD Ensembl Show fit	histone cluster 2, H3c2
chr10_+_12046541 Show fit	86.15	ENSRNOT00000081191	Mefv NCBI RGD Ensembl Show fit	MEFV, pyrin innate immunity regulator
chr12_-_9331195 Show fit	85.26	ENSRNOT00000044134	Pan3 NCBI RGD Ensembl Show fit	PAN3 poly(A) specific ribonuclease subunit
chr4_-_34282351 Show fit	85.18	ENSRNOT00000011123	Rpa3 NCBI RGD Ensembl Show fit	replication protein A3
chr1_-_227441442 Show fit	84.98	ENSRNOT00000028433	Ms4a1 NCBI RGD Ensembl Show fit	membrane spanning 4-domains A1
chr2_+_187218851 Show fit	84.39	ENSRNOT00000017798	Sh2d2a NCBI RGD Ensembl Show fit	SH2 domain containing 2A
chr4_-_113866674 Show fit	84.28	ENSRNOT00000010020	Dok1 NCBI RGD Ensembl Show fit	docking protein 1
chr13_+_90759260 Show fit	83.16	ENSRNOT00000010551	Pigm NCBI RGD Ensembl Show fit	phosphatidylinositol glycan anchor biosynthesis, class M
chr10_-_94500591 Show fit	82.77	ENSRNOT00000015976	Cd79b NCBI RGD Ensembl Show fit	CD79b molecule
chr20_+_3875706 Show fit	82.43	ENSRNOT00000036900	RT1-Ha NCBI RGD Ensembl Show fit	RT1 class II, locus Ha
chr13_+_51958834 Show fit	82.11	ENSRNOT00000007833	Ptpn7 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 7
chrX_+_70461718 Show fit	81.99	ENSRNOT00000078233 ENSRNOT00000003789	Kif4a NCBI RGD Ensembl Show fit	kinesin family member 4A
chr8_-_49280901 Show fit	81.83	ENSRNOT00000021390	Cd3g NCBI RGD Ensembl Show fit	CD3g molecule
chr7_-_94774569 Show fit	81.71	ENSRNOT00000036399	Dscc1 NCBI RGD Ensembl Show fit	DNA replication and sister chromatid cohesion 1
chr20_+_4020317 Show fit	80.87	ENSRNOT00000000526	RT1-DOb NCBI RGD Ensembl Show fit	RT1 class II, locus DOb
chr7_+_70614617 Show fit	80.58	ENSRNOT00000035382	Arhgap9 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 9
chr2_+_183674522 Show fit	79.82	ENSRNOT00000014433	Tmem154 NCBI RGD Ensembl Show fit	transmembrane protein 154
chr4_+_152892599 Show fit	79.53	ENSRNOT00000079090	Kdm5a NCBI RGD Ensembl Show fit	lysine demethylase 5A
chr14_-_71814523 Show fit	79.14	ENSRNOT00000004094	Bst1 NCBI RGD Ensembl Show fit	bone marrow stromal cell antigen 1
chr19_+_25077918 Show fit	78.98	ENSRNOT00000006964	Asf1b NCBI RGD Ensembl Show fit	anti-silencing function 1B histone chaperone
chr12_+_2180150 Show fit	78.17	ENSRNOT00000001322	Stxbp2 NCBI RGD Ensembl Show fit	syntaxin binding protein 2
chr1_+_81779380 Show fit	77.94	ENSRNOT00000065865 ENSRNOT00000080143 ENSRNOT00000089592 ENSRNOT00000080840	Arhgef1 NCBI RGD Ensembl Show fit	Rho guanine nucleotide exchange factor 1
chr5_-_76756140 Show fit	77.67	ENSRNOT00000022107 ENSRNOT00000089251	Ptbp3 NCBI RGD Ensembl Show fit	polypyrimidine tract binding protein 3
chr10_+_12046701 Show fit	77.56	ENSRNOT00000011073 ENSRNOT00000084004	Mefv NCBI RGD Ensembl Show fit	MEFV, pyrin innate immunity regulator
chr5_-_147761983 Show fit	77.51	ENSRNOT00000012936	Lck NCBI RGD Ensembl Show fit	LCK proto-oncogene, Src family tyrosine kinase
chr11_-_54404612 Show fit	77.27	ENSRNOT00000033837	RGD1310335 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA C330027C09
chr2_+_52333396 Show fit	76.93	ENSRNOT00000046174	RGD1306227 NCBI RGD Ensembl Show fit	similar to 4833420G17Rik protein
chr1_-_219438779 Show fit	76.57	ENSRNOT00000029237	Tbc1d10c NCBI RGD Ensembl Show fit	TBC1 domain family, member 10C
chr6_-_141147264 Show fit	74.96	ENSRNOT00000042900	LOC100361105 NCBI RGD Ensembl Show fit	Igh protein-like
chr1_+_242959488 Show fit	74.47	ENSRNOT00000015668	Dock8 NCBI RGD Ensembl Show fit	dedicator of cytokinesis 8
chr17_-_76410294 Show fit	74.13	ENSRNOT00000023892	Nudt5 NCBI RGD Ensembl Show fit	nudix hydrolase 5
chr10_-_30118873 Show fit	74.04	ENSRNOT00000006063	Ublcp1 NCBI RGD Ensembl Show fit	ubiquitin-like domain containing CTD phosphatase 1
chr1_-_213907144 Show fit	73.86	ENSRNOT00000054874	Sigirr NCBI RGD Ensembl Show fit	single Ig and TIR domain containing
chr6_-_36940868 Show fit	73.75	ENSRNOT00000006470	Gen1 NCBI RGD Ensembl Show fit	GEN1 Holliday junction 5' flap endonuclease
chr7_-_119797098 Show fit	72.85	ENSRNOT00000009994	Rac2 NCBI RGD Ensembl Show fit	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr14_-_86796378 Show fit	72.31	ENSRNOT00000092021	Myo1g NCBI RGD Ensembl Show fit	myosin IG
chr17_-_78812111 Show fit	72.24	ENSRNOT00000021506	Dclre1c NCBI RGD Ensembl Show fit	DNA cross-link repair 1C
chr13_+_83996080 Show fit	72.24	ENSRNOT00000004403 ENSRNOT00000070958	Cd247 NCBI RGD Ensembl Show fit	Cd247 molecule
chr3_-_160739137 Show fit	72.19	ENSRNOT00000075836	Slpil2 NCBI RGD Ensembl Show fit	antileukoproteinase-like 2
chr5_-_147803851 Show fit	72.08	ENSRNOT00000071922	Eif3i NCBI RGD Ensembl Show fit	eukaryotic translation initiation factor 3, subunit I
chrX_+_134979646 Show fit	72.01	ENSRNOT00000006035	Sash3 NCBI RGD Ensembl Show fit	SAM and SH3 domain containing 3
chr4_-_157263890 Show fit	70.77	ENSRNOT00000065416	Ptpn6 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 6
chr6_+_109562587 Show fit	70.13	ENSRNOT00000011563	Batf NCBI RGD Ensembl Show fit	basic leucine zipper ATF-like transcription factor
chr3_-_160738927 Show fit	69.91	ENSRNOT00000043470	Slpil2 NCBI RGD Ensembl Show fit	antileukoproteinase-like 2
chr11_-_54514441 Show fit	69.82	ENSRNOT00000002673	Retnlg NCBI RGD Ensembl Show fit	resistin-like gamma
chr1_-_89473904 Show fit	69.66	ENSRNOT00000089474	Fxyd5 NCBI RGD Ensembl Show fit	FXYD domain-containing ion transport regulator 5
chr3_+_159995064 Show fit	69.18	ENSRNOT00000012606	Ttpal NCBI RGD Ensembl Show fit	alpha tocopherol transfer protein like
chr7_+_95309928 Show fit	69.16	ENSRNOT00000005887	Mtbp NCBI RGD Ensembl Show fit	MDM2 binding protein
chr4_+_152892388 Show fit	69.14	ENSRNOT00000056198 ENSRNOT00000090218 ENSRNOT00000075895	Kdm5a NCBI RGD Ensembl Show fit	lysine demethylase 5A
chr5_+_142845114 Show fit	68.27	ENSRNOT00000039870	Yrdc NCBI RGD Ensembl Show fit	yrdC N(6)-threonylcarbamoyltransferase domain containing
chr10_+_56187679 Show fit	67.91	ENSRNOT00000085115	Tp53 NCBI RGD Ensembl Show fit	tumor protein p53
chr14_-_69927938 Show fit	66.76	ENSRNOT00000058838	Ncapg NCBI RGD Ensembl Show fit	non-SMC condensin I complex, subunit G
chr12_+_13716596 Show fit	66.42	ENSRNOT00000080216	Actb NCBI RGD Ensembl Show fit	actin, beta
chr16_-_21380331 Show fit	66.07	ENSRNOT00000015247	Atp13a1 NCBI RGD Ensembl Show fit	ATPase 13A1
chr8_-_71533069 Show fit	65.91	ENSRNOT00000021863	Trip4 NCBI RGD Ensembl Show fit	thyroid hormone receptor interactor 4
chr20_-_4863198 Show fit	65.78	ENSRNOT00000001108	Ltb NCBI RGD Ensembl Show fit	lymphotoxin beta
chr11_-_87628502 Show fit	65.46	ENSRNOT00000002568	Med15 NCBI RGD Ensembl Show fit	mediator complex subunit 15
chr7_+_119482272 Show fit	65.07	ENSRNOT00000009544	Ncf4 NCBI RGD Ensembl Show fit	neutrophil cytosolic factor 4
chr2_+_212257225 Show fit	65.00	ENSRNOT00000077883	Vav3 NCBI RGD Ensembl Show fit	vav guanine nucleotide exchange factor 3
chr10_-_104054805 Show fit	64.68	ENSRNOT00000004853	Nt5c NCBI RGD Ensembl Show fit	5', 3'-nucleotidase, cytosolic
chr3_+_28627084 Show fit	64.49	ENSRNOT00000049884	Arhgap15 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 15
chr11_-_66759402 Show fit	64.45	ENSRNOT00000003326	Hcls1 NCBI RGD Ensembl Show fit	hematopoietic cell specific Lyn substrate 1
chr17_+_43734461 Show fit	64.45	ENSRNOT00000072564	Hist1h1d NCBI RGD Ensembl Show fit	histone cluster 1, H1d
chr1_-_198225580 Show fit	64.44	ENSRNOT00000026909	Ppp4c NCBI RGD Ensembl Show fit	protein phosphatase 4, catalytic subunit
chr16_-_7588841 Show fit	64.44	ENSRNOT00000084645	Mettl6 NCBI RGD Ensembl Show fit	methyltransferase like 6
chr14_-_18849258 Show fit	64.36	ENSRNOT00000033406	Pf4 NCBI RGD Ensembl Show fit	platelet factor 4
chr8_+_115131367 Show fit	63.80	ENSRNOT00000014849	Rpl29 NCBI RGD Ensembl Show fit	ribosomal protein L29
chr13_+_98615287 Show fit	63.41	ENSRNOT00000004032	Itpkb NCBI RGD Ensembl Show fit	inositol-trisphosphate 3-kinase B
chr3_+_110618298 Show fit	63.08	ENSRNOT00000012454	Knstrn NCBI RGD Ensembl Show fit	kinetochore-localized astrin/SPAG5 binding protein
chr4_-_78342863 Show fit	62.97	ENSRNOT00000049038	Gimap6 NCBI RGD Ensembl Show fit	GTPase, IMAP family member 6
chr1_-_198577226 Show fit	62.66	ENSRNOT00000055013	Spn NCBI RGD Ensembl Show fit	sialophorin
chr3_+_148327965 Show fit	61.77	ENSRNOT00000010851 ENSRNOT00000088481	Tpx2 NCBI RGD Ensembl Show fit	TPX2, microtubule nucleation factor
chr1_+_81230989 Show fit	61.75	ENSRNOT00000077952	Kcnn4 NCBI RGD Ensembl Show fit	potassium calcium-activated channel subfamily N member 4
chr17_+_22984844 Show fit	61.41	ENSRNOT00000078310	Nedd9 NCBI RGD Ensembl Show fit	neural precursor cell expressed, developmentally down-regulated 9
chr3_-_14643897 Show fit	61.35	ENSRNOT00000082008 ENSRNOT00000025983	Ggta1 NCBI RGD Ensembl Show fit	glycoprotein, alpha-galactosyltransferase 1
chr10_+_94566928 Show fit	61.25	ENSRNOT00000078446	Prr29 NCBI RGD Ensembl Show fit	proline rich 29
chr7_+_125288081 Show fit	61.19	ENSRNOT00000085216	Parvg NCBI RGD Ensembl Show fit	parvin, gamma
chr20_+_5184515 Show fit	61.02	ENSRNOT00000089411	LOC103694381 NCBI RGD Ensembl Show fit	lymphotoxin-beta
chr2_-_187909394 Show fit	60.94	ENSRNOT00000032355	Rab25 NCBI RGD Ensembl Show fit	RAB25, member RAS oncogene family
chr1_-_225952516 Show fit	60.78	ENSRNOT00000043387	Incenp NCBI RGD Ensembl Show fit	inner centromere protein
chr6_-_142585188 Show fit	60.30	ENSRNOT00000067437	AABR07065815.1 NCBI RGD Ensembl Show fit
chr18_+_86299463 Show fit	60.06	ENSRNOT00000058152	Cd226 NCBI RGD Ensembl Show fit	CD226 molecule
chr3_+_72395218 Show fit	59.64	ENSRNOT00000057616	Prg3 NCBI RGD Ensembl Show fit	proteoglycan 3, pro eosinophil major basic protein 2
chr9_+_65620658 Show fit	59.25	ENSRNOT00000084498	Casp8 NCBI RGD Ensembl Show fit	caspase 8
chr8_+_117355943 Show fit	59.14	ENSRNOT00000027318	Dalrd3 NCBI RGD Ensembl Show fit	DALR anticodon binding domain containing 3
chr19_+_37652969 Show fit	58.99	ENSRNOT00000041970	Carmil2 NCBI RGD Ensembl Show fit	capping protein regulator and myosin 1 linker 2
chr9_-_92616165 Show fit	58.88	ENSRNOT00000056995	Sp110 NCBI RGD Ensembl Show fit	SP110 nuclear body protein
chr10_+_106856097 Show fit	58.69	ENSRNOT00000072387	Birc5 NCBI RGD Ensembl Show fit	baculoviral IAP repeat-containing 5
chr3_+_1478525 Show fit	58.66	ENSRNOT00000008161	Psd4 NCBI RGD Ensembl Show fit	pleckstrin and Sec7 domain containing 4
chr5_-_118541928 Show fit	58.57	ENSRNOT00000012947	Itgb3bp NCBI RGD Ensembl Show fit	integrin subunit beta 3 binding protein
chr16_+_73584521 Show fit	58.46	ENSRNOT00000024301	Gins4 NCBI RGD Ensembl Show fit	GINS complex subunit 4
chr4_-_115354795 Show fit	58.34	ENSRNOT00000017691	Cd207 NCBI RGD Ensembl Show fit	CD207 molecule
chr18_-_28535828 Show fit	58.33	ENSRNOT00000068386	Tmem173 NCBI RGD Ensembl Show fit	transmembrane protein 173
chr7_+_70612103 Show fit	58.25	ENSRNOT00000057833	Arhgap9 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 9
chr4_+_69384145 Show fit	58.16	ENSRNOT00000084834	Trbv13-2 NCBI RGD Ensembl Show fit	T cell receptor beta, variable 13-2
chr12_-_11265865 Show fit	57.88	ENSRNOT00000001315	Arpc1b NCBI RGD Ensembl Show fit	actin related protein 2/3 complex, subunit 1B
chr1_+_219403970 Show fit	57.82	ENSRNOT00000029607	Ptprcap NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type, C-associated protein
chr8_+_11888591 Show fit	57.75	ENSRNOT00000083967	Ccdc82 NCBI RGD Ensembl Show fit	coiled-coil domain containing 82
chr15_-_29443454 Show fit	57.72	ENSRNOT00000082167	AABR07017635.2 NCBI RGD Ensembl Show fit
chr9_-_17835240 Show fit	57.68	ENSRNOT00000026988	Nfkbie NCBI RGD Ensembl Show fit	NFKB inhibitor epsilon
chr17_+_44763598 Show fit	57.56	ENSRNOT00000079880	Hist1h3b NCBI RGD Ensembl Show fit	histone cluster 1, H3b
chr15_+_32614002 Show fit	57.28	ENSRNOT00000072962	AABR07017902.1 NCBI RGD Ensembl Show fit
chr2_-_241545250 Show fit	56.87	ENSRNOT00000073875	Bank1 NCBI RGD Ensembl Show fit	B-cell scaffold protein with ankyrin repeats 1
chr6_-_139041812 Show fit	56.83	ENSRNOT00000074510	AABR07065656.1 NCBI RGD Ensembl Show fit
chr3_+_152909189 Show fit	56.73	ENSRNOT00000066341	Tgif2 NCBI RGD Ensembl Show fit	TGFB-induced factor homeobox 2
chr15_+_31989041 Show fit	56.69	ENSRNOT00000073686	AABR07017868.2 NCBI RGD Ensembl Show fit
chr4_+_101645731 Show fit	56.10	ENSRNOT00000087901	AABR07060953.1 NCBI RGD Ensembl Show fit
chr15_-_29465807 Show fit	56.08	ENSRNOT00000075046	AABR07017635.1 NCBI RGD Ensembl Show fit
chr8_-_71118927 Show fit	55.56	ENSRNOT00000042633	Plekho2 NCBI RGD Ensembl Show fit	pleckstrin homology domain containing O2
chr11_+_85508300 Show fit	55.13	ENSRNOT00000038646	AABR07034730.3 NCBI RGD Ensembl Show fit
chr10_+_56576428 Show fit	55.04	ENSRNOT00000079237 ENSRNOT00000023291	Cldn7 NCBI RGD Ensembl Show fit	claudin 7
chr1_-_199439210 Show fit	54.67	ENSRNOT00000026699	Pycard NCBI RGD Ensembl Show fit	PYD and CARD domain containing
chr15_-_70399924 Show fit	54.60	ENSRNOT00000087940	Diaph3 NCBI RGD Ensembl Show fit	diaphanous-related formin 3
chr3_+_7635933 Show fit	54.26	ENSRNOT00000061029	Ttf1 NCBI RGD Ensembl Show fit	transcription termination factor 1
chr7_+_145068286 Show fit	54.20	ENSRNOT00000088956 ENSRNOT00000065753	Nckap1l NCBI RGD Ensembl Show fit	NCK associated protein 1 like
chr4_+_69138525 Show fit	54.13	ENSRNOT00000073589	Trbv1 NCBI RGD Ensembl Show fit	T cell receptor beta, variable 1
chr1_-_265798167 Show fit	54.08	ENSRNOT00000079483	Ldb1 NCBI RGD Ensembl Show fit	LIM domain binding 1
chr10_-_87067456 Show fit	54.01	ENSRNOT00000014163	Ccr7 NCBI RGD Ensembl Show fit	C-C motif chemokine receptor 7
chr17_+_44556039 Show fit	53.73	ENSRNOT00000086540	Prss16 NCBI RGD Ensembl Show fit	protease, serine 16
chr1_-_47502952 Show fit	53.67	ENSRNOT00000025580	Tagap NCBI RGD Ensembl Show fit	T-cell activation RhoGTPase activating protein
chr3_+_112531703 Show fit	53.64	ENSRNOT00000041727	LOC100911204 NCBI RGD Ensembl Show fit	protein CASC5-like
chr1_-_100559942 Show fit	53.57	ENSRNOT00000026862	Nr1h2 NCBI RGD Ensembl Show fit	nuclear receptor subfamily 1, group H, member 2
chr17_+_43632397 Show fit	53.36	ENSRNOT00000013790	Hist1h2ah NCBI RGD Ensembl Show fit	histone cluster 1, H2ah
chr9_+_10952374 Show fit	53.24	ENSRNOT00000074993	Lrg1 NCBI RGD Ensembl Show fit	leucine-rich alpha-2-glycoprotein 1
chr1_-_198128857 Show fit	53.20	ENSRNOT00000026496	Coro1a NCBI RGD Ensembl Show fit	coronin 1A
chr1_+_189550354 Show fit	53.09	ENSRNOT00000083153	Exnef NCBI RGD Ensembl Show fit	exonuclease NEF-sp
chr1_-_142020525 Show fit	53.08	ENSRNOT00000042558	Cib1 NCBI RGD Ensembl Show fit	calcium and integrin binding 1
chr2_-_196323881 Show fit	53.04	ENSRNOT00000028642	Tnfaip8l2 NCBI RGD Ensembl Show fit	TNF alpha induced protein 8 like 2
chr10_-_70341837 Show fit	52.92	ENSRNOT00000077261	Slfn13 NCBI RGD Ensembl Show fit	schlafen family member 13
chr13_-_108178609 Show fit	52.89	ENSRNOT00000004525	Cenpf NCBI RGD Ensembl Show fit	centromere protein F
chr8_+_99625545 Show fit	52.87	ENSRNOT00000010689 ENSRNOT00000056727	Plscr1 NCBI RGD Ensembl Show fit	phospholipid scramblase 1
chr13_+_90116843 Show fit	52.87	ENSRNOT00000006306	Cd48 NCBI RGD Ensembl Show fit	Cd48 molecule
chr4_+_118167294 Show fit	52.53	ENSRNOT00000022367	LOC687679 NCBI RGD Ensembl Show fit	similar to small nuclear ribonucleoprotein polypeptide G
chr14_-_43992587 Show fit	52.39	ENSRNOT00000003425	Rhoh NCBI RGD Ensembl Show fit	ras homolog family member H
chr4_+_100209951 Show fit	52.31	ENSRNOT00000015807	LOC691113 NCBI RGD Ensembl Show fit	hypothetical protein LOC691113
chr15_+_30785248 Show fit	52.26	ENSRNOT00000089085	AABR07017768.5 NCBI RGD Ensembl Show fit
chr15_-_30323833 Show fit	52.09	ENSRNOT00000071631	AABR07017714.1 NCBI RGD Ensembl Show fit
chr4_+_99239115 Show fit	51.92	ENSRNOT00000009515	Cd8a NCBI RGD Ensembl Show fit	CD8a molecule
chr2_+_219628695 Show fit	51.75	ENSRNOT00000067324	Sass6 NCBI RGD Ensembl Show fit	SAS-6 centriolar assembly protein
chr9_+_65614142 Show fit	51.67	ENSRNOT00000016613	Casp8 NCBI RGD Ensembl Show fit	caspase 8
chr16_-_48921242 Show fit	51.63	ENSRNOT00000041596	Cenpu NCBI RGD Ensembl Show fit	centromere protein U
chr7_+_126736732 Show fit	51.39	ENSRNOT00000022012	Gtse1 NCBI RGD Ensembl Show fit	G-2 and S-phase expressed 1
chr6_-_9459188 Show fit	51.37	ENSRNOT00000019894	Srbd1 NCBI RGD Ensembl Show fit	S1 RNA binding domain 1
chr13_-_89606326 Show fit	51.32	ENSRNOT00000029179	Fcer1g NCBI RGD Ensembl Show fit	Fc fragment of IgE receptor Ig
chr8_-_61823102 Show fit	50.94	ENSRNOT00000058645	Neil1 NCBI RGD Ensembl Show fit	nei-like DNA glycosylase 1
chr20_+_5040337 Show fit	50.52	ENSRNOT00000068435	Clic1 NCBI RGD Ensembl Show fit	chloride intracellular channel 1
chr20_-_4070721 Show fit	50.36	ENSRNOT00000000523	RT1-Ba NCBI RGD Ensembl Show fit	RT1 class II, locus Ba
chr5_-_57683932 Show fit	50.22	ENSRNOT00000074796	Dcaf12 NCBI RGD Ensembl Show fit	DDB1 and CUL4 associated factor 12
chr8_-_33661049 Show fit	50.21	ENSRNOT00000068037	Fli1 NCBI RGD Ensembl Show fit	Fli-1 proto-oncogene, ETS transcription factor
chr1_+_189549960 Show fit	50.19	ENSRNOT00000019654	Exnef NCBI RGD Ensembl Show fit	exonuclease NEF-sp
chr1_-_20417637 Show fit	50.16	ENSRNOT00000036049	RGD1559962 NCBI RGD Ensembl Show fit	similar to High mobility group protein 2 (HMG-2)
chr16_-_9430743 Show fit	50.14	ENSRNOT00000043811	Wdfy4 NCBI RGD Ensembl Show fit	WDFY family member 4
chr19_-_39087880 Show fit	50.04	ENSRNOT00000070822	Chtf8 NCBI RGD Ensembl Show fit	chromosome transmission fidelity factor 8
chr2_-_189573280 Show fit	50.02	ENSRNOT00000022897	Rps27 NCBI RGD Ensembl Show fit	ribosomal protein S27
chr18_+_27657628 Show fit	49.98	ENSRNOT00000026303	Egr1 NCBI RGD Ensembl Show fit	early growth response 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Elf1_Elf2_Etv2_Elf4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
55.7	278.4	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
49.6	148.7	GO:1901726	negative regulation of histone deacetylase activity(GO:1901726)
44.2	176.8	GO:0002586	regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
32.8	98.4	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
32.6	97.8	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
31.2	93.5	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
30.2	151.0	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
29.0	260.7	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
28.3	85.0	GO:0007056	spindle assembly involved in female meiosis(GO:0007056)
28.1	84.4	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
28.0	307.5	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
27.9	111.4	GO:0033277	abortive mitotic cell cycle(GO:0033277)
27.7	110.9	GO:0006014	D-ribose metabolic process(GO:0006014)
27.2	108.7	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
26.6	106.5	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
26.1	52.2	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
25.6	76.9	GO:0042531	regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
25.5	255.1	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
25.3	151.6	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
25.2	100.9	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
25.1	25.1	GO:0060101	negative regulation of phagocytosis, engulfment(GO:0060101)
24.9	373.4	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
24.7	148.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
24.0	96.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
23.9	286.3	GO:0001771	immunological synapse formation(GO:0001771)
23.6	70.8	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
22.9	91.7	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
22.5	67.6	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
22.5	67.6	GO:2000417	negative regulation of eosinophil migration(GO:2000417)
22.3	44.7	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
22.3	67.0	GO:1904569	regulation of selenocysteine incorporation(GO:1904569)
22.1	22.1	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
22.1	66.2	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
21.3	63.8	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
21.2	63.7	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
21.1	63.4	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
21.1	63.3	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
21.0	21.0	GO:0060557	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
21.0	63.1	GO:0002149	hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
21.0	21.0	GO:0060375	regulation of mast cell differentiation(GO:0060375)
20.4	61.3	GO:0033580	protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
20.2	100.8	GO:2000553	positive regulation of T-helper 2 cell cytokine production(GO:2000553)
20.1	100.5	GO:0072717	cellular response to actinomycin D(GO:0072717)
20.1	80.2	GO:0006701	progesterone biosynthetic process(GO:0006701)
20.0	60.1	GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
19.8	178.2	GO:0032831	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
19.7	19.7	GO:0002277	myeloid dendritic cell activation involved in immune response(GO:0002277)
19.6	195.6	GO:1901978	positive regulation of cell cycle checkpoint(GO:1901978)
19.1	57.4	GO:1904586	response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586)
19.0	190.0	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
18.9	37.9	GO:0002326	B cell lineage commitment(GO:0002326)
18.5	55.6	GO:1905218	cellular response to astaxanthin(GO:1905218)
18.4	55.1	GO:0045575	basophil activation(GO:0045575)
18.1	54.3	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
17.9	17.9	GO:2000253	positive regulation of feeding behavior(GO:2000253)
17.9	71.6	GO:2000814	positive regulation of barbed-end actin filament capping(GO:2000814)
17.4	69.5	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
17.4	52.1	GO:0006667	sphinganine metabolic process(GO:0006667)
17.2	17.2	GO:0034418	urate biosynthetic process(GO:0034418)
17.1	51.2	GO:1904882	telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
17.0	85.0	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
17.0	84.8	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
16.9	33.9	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
16.9	16.9	GO:0002434	immune complex clearance(GO:0002434)
16.9	33.8	GO:0006308	DNA catabolic process(GO:0006308)
16.9	84.3	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
16.8	50.5	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
16.6	99.8	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
16.5	49.6	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
16.2	32.4	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
16.2	64.7	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
16.1	64.6	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
16.0	47.9	GO:0019417	sulfur oxidation(GO:0019417)
15.9	47.8	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
15.9	47.7	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
15.9	31.8	GO:0019323	pentose catabolic process(GO:0019323)
15.9	79.3	GO:0002457	T cell antigen processing and presentation(GO:0002457)
15.9	47.6	GO:1905132	metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
15.7	62.8	GO:0034240	negative regulation of macrophage fusion(GO:0034240)
15.6	77.8	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
15.6	46.7	GO:0072697	protein localization to cell cortex(GO:0072697)
15.4	92.4	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
15.4	46.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
15.4	46.1	GO:2001183	negative regulation of interleukin-12 secretion(GO:2001183)
15.2	60.8	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
15.1	30.3	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
15.0	105.0	GO:0051256	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
15.0	74.8	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
14.9	44.6	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
14.9	44.6	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
14.8	399.5	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
14.7	58.9	GO:2000813	negative regulation of barbed-end actin filament capping(GO:2000813)
14.7	58.6	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
14.6	29.2	GO:0002654	regulation of tolerance induction dependent upon immune response(GO:0002652) positive regulation of tolerance induction dependent upon immune response(GO:0002654)
14.5	43.4	GO:1904170	regulation of bleb assembly(GO:1904170)
14.4	43.3	GO:0032298	positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
14.4	100.5	GO:0070269	pyroptosis(GO:0070269)
14.3	185.7	GO:0007076	mitotic chromosome condensation(GO:0007076)
14.2	56.8	GO:1903238	positive regulation of leukocyte tethering or rolling(GO:1903238)
14.1	42.2	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
14.0	42.1	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
13.7	68.3	GO:0090187	positive regulation of pancreatic juice secretion(GO:0090187)
13.5	53.9	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
13.4	53.7	GO:0032074	negative regulation of nuclease activity(GO:0032074)
13.4	93.7	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
13.4	40.1	GO:0045210	FasL biosynthetic process(GO:0045210)
13.4	40.1	GO:0042631	cellular response to water deprivation(GO:0042631)
13.2	105.5	GO:0016584	nucleosome positioning(GO:0016584)
13.1	39.4	GO:1902963	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
13.1	26.3	GO:0071283	cellular response to iron(III) ion(GO:0071283)
13.1	52.5	GO:0002184	cytoplasmic translational termination(GO:0002184)
13.1	104.6	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
13.1	26.1	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
13.0	39.1	GO:0046967	cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
13.0	52.1	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
13.0	39.0	GO:0021997	neural plate axis specification(GO:0021997)
12.8	64.0	GO:0019371	cyclooxygenase pathway(GO:0019371)
12.8	51.1	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
12.7	38.0	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
12.6	113.6	GO:0034501	protein localization to kinetochore(GO:0034501)
12.6	37.8	GO:1901227	negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
12.5	50.2	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
12.5	25.0	GO:0071224	cellular response to peptidoglycan(GO:0071224)
12.5	75.0	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
12.4	37.2	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
12.1	48.5	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
12.1	48.2	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
12.0	48.1	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
12.0	12.0	GO:0044253	positive regulation of multicellular organismal metabolic process(GO:0044253)
12.0	23.9	GO:0006407	rRNA export from nucleus(GO:0006407)
12.0	35.9	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
11.9	155.3	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
11.8	58.9	GO:0000454	snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
11.7	151.7	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
11.6	11.6	GO:0002191	cap-dependent translational initiation(GO:0002191)
11.6	34.8	GO:0060821	inactivation of X chromosome by DNA methylation(GO:0060821)
11.6	197.2	GO:0001833	inner cell mass cell proliferation(GO:0001833)
11.6	138.8	GO:0043249	erythrocyte maturation(GO:0043249)
11.6	80.9	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
11.5	23.0	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
11.4	34.2	GO:2000667	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
11.4	11.4	GO:0030221	basophil differentiation(GO:0030221)
11.3	283.3	GO:0048305	immunoglobulin secretion(GO:0048305)
11.3	45.2	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
11.2	56.0	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
11.2	22.4	GO:2000318	positive regulation of T-helper 17 type immune response(GO:2000318)
11.1	55.5	GO:0010360	negative regulation of anion channel activity(GO:0010360)
11.1	55.5	GO:0007144	female meiosis I(GO:0007144)
11.1	11.1	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
11.0	33.1	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
10.9	32.8	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
10.9	87.3	GO:0002315	marginal zone B cell differentiation(GO:0002315)
10.8	32.4	GO:0071348	cellular response to interleukin-11(GO:0071348)
10.7	75.1	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
10.7	10.7	GO:0002339	B cell selection(GO:0002339)
10.7	21.4	GO:1902751	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
10.6	31.9	GO:0014739	positive regulation of muscle hyperplasia(GO:0014739)
10.6	31.8	GO:0070475	rRNA base methylation(GO:0070475)
10.6	84.7	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
10.6	116.1	GO:0002467	germinal center formation(GO:0002467)
10.5	10.5	GO:0000019	regulation of mitotic recombination(GO:0000019)
10.5	21.0	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
10.5	21.0	GO:0002344	peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
10.5	21.0	GO:0009608	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
10.5	31.4	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
10.4	62.4	GO:0061737	leukotriene signaling pathway(GO:0061737)
10.4	103.9	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
10.4	62.2	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
10.4	93.3	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
10.3	93.0	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
10.3	10.3	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
10.2	50.8	GO:0032202	telomere assembly(GO:0032202)
10.1	50.7	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
10.1	70.7	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
10.1	120.9	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
10.1	30.2	GO:0038158	granulocyte colony-stimulating factor signaling pathway(GO:0038158)
10.0	29.9	GO:0021747	cochlear nucleus development(GO:0021747)
9.9	168.4	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
9.9	9.9	GO:0002431	Fc receptor mediated stimulatory signaling pathway(GO:0002431)
9.9	9.9	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
9.9	88.8	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
9.8	275.6	GO:0007080	mitotic metaphase plate congression(GO:0007080)
9.8	59.0	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
9.8	29.5	GO:0051105	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
9.8	19.6	GO:0033364	mast cell secretory granule organization(GO:0033364)
9.7	29.2	GO:0030578	PML body organization(GO:0030578)
9.7	29.1	GO:0071461	cellular response to redox state(GO:0071461)
9.7	38.7	GO:0042256	mature ribosome assembly(GO:0042256)
9.6	28.9	GO:2000872	positive regulation of progesterone secretion(GO:2000872)
9.5	37.9	GO:2001166	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
9.4	131.1	GO:0002283	neutrophil activation involved in immune response(GO:0002283)
9.3	74.7	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
9.3	18.7	GO:2000464	positive regulation of astrocyte chemotaxis(GO:2000464)
9.3	9.3	GO:1990253	cellular response to leucine starvation(GO:1990253)
9.3	27.9	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
9.3	18.6	GO:0036388	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
9.3	27.9	GO:0048210	Golgi vesicle fusion to target membrane(GO:0048210)
9.3	37.1	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
9.2	295.3	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
9.2	36.8	GO:0030263	apoptotic chromosome condensation(GO:0030263)
9.1	36.6	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
9.1	36.5	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
9.0	27.0	GO:0060490	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
9.0	71.9	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
8.9	17.8	GO:0090669	telomerase RNA stabilization(GO:0090669)
8.9	8.9	GO:0006408	snRNA export from nucleus(GO:0006408)
8.9	44.3	GO:0030223	neutrophil differentiation(GO:0030223)
8.8	17.7	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
8.7	96.2	GO:0034724	DNA replication-independent nucleosome organization(GO:0034724)
8.7	26.2	GO:0042350	GDP-L-fucose biosynthetic process(GO:0042350)
8.7	43.6	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
8.7	26.2	GO:0036066	protein O-linked fucosylation(GO:0036066)
8.7	26.1	GO:1902463	protein localization to cell leading edge(GO:1902463)
8.7	34.8	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
8.7	26.1	GO:0033566	gamma-tubulin complex localization(GO:0033566)
8.5	17.1	GO:0001806	type IV hypersensitivity(GO:0001806) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
8.5	162.2	GO:0006270	DNA replication initiation(GO:0006270)
8.5	25.6	GO:0002777	antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
8.5	25.6	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
8.5	498.8	GO:0070527	platelet aggregation(GO:0070527)
8.3	24.9	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
8.2	33.0	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
8.2	16.4	GO:1904674	positive regulation of somatic stem cell population maintenance(GO:1904674)
8.2	98.4	GO:0050765	negative regulation of phagocytosis(GO:0050765)
8.2	49.2	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
8.2	24.6	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
8.2	89.8	GO:0002360	T cell lineage commitment(GO:0002360)
8.1	276.1	GO:0050853	B cell receptor signaling pathway(GO:0050853)
8.1	64.8	GO:0030259	lipid glycosylation(GO:0030259)
8.1	24.3	GO:0036260	7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
8.1	16.1	GO:0046864	isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
8.1	16.1	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
8.0	32.2	GO:0042148	strand invasion(GO:0042148)
8.0	56.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
8.0	48.0	GO:0097039	protein linear polyubiquitination(GO:0097039)
7.9	15.9	GO:0043366	beta selection(GO:0043366)
7.9	87.4	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
7.9	47.7	GO:0010216	maintenance of DNA methylation(GO:0010216)
7.9	31.7	GO:1904580	regulation of intracellular mRNA localization(GO:1904580)
7.9	94.8	GO:0006265	DNA topological change(GO:0006265)
7.8	109.8	GO:0042832	defense response to protozoan(GO:0042832)
7.8	172.5	GO:0000027	ribosomal large subunit assembly(GO:0000027)
7.8	47.0	GO:0071763	nuclear membrane organization(GO:0071763)
7.8	15.6	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
7.8	54.5	GO:2000210	positive regulation of anoikis(GO:2000210)
7.8	23.3	GO:0043247	telomere maintenance in response to DNA damage(GO:0043247)
7.8	15.5	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
7.7	46.5	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
7.7	61.6	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
7.7	69.3	GO:0050716	positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
7.7	23.0	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
7.7	23.0	GO:0003162	atrioventricular node development(GO:0003162)
7.6	137.5	GO:0031297	replication fork processing(GO:0031297)
7.5	346.7	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
7.5	30.1	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
7.5	15.0	GO:0051136	regulation of NK T cell differentiation(GO:0051136)
7.4	7.4	GO:0033045	regulation of sister chromatid segregation(GO:0033045)
7.4	14.7	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
7.4	7.4	GO:1903772	regulation of viral budding via host ESCRT complex(GO:1903772)
7.3	36.7	GO:0000706	meiotic DNA double-strand break processing(GO:0000706)
7.3	29.3	GO:0097681	double-strand break repair via alternative nonhomologous end joining(GO:0097681)
7.3	29.3	GO:0002084	protein depalmitoylation(GO:0002084)
7.3	14.5	GO:0080144	amino acid homeostasis(GO:0080144)
7.3	14.5	GO:0048254	snoRNA localization(GO:0048254)
7.2	21.7	GO:0055099	response to high density lipoprotein particle(GO:0055099)
7.2	21.7	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
7.2	21.7	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
7.2	14.4	GO:1902211	regulation of prolactin signaling pathway(GO:1902211)
7.2	57.5	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
7.2	42.9	GO:0080009	mRNA methylation(GO:0080009)
7.1	21.3	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
7.1	14.1	GO:0032258	CVT pathway(GO:0032258)
7.0	21.1	GO:0030043	actin filament fragmentation(GO:0030043)
7.0	28.1	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
7.0	7.0	GO:0061741	vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
7.0	21.0	GO:0021764	amygdala development(GO:0021764)
7.0	27.9	GO:0007296	vitellogenesis(GO:0007296)
7.0	7.0	GO:0035261	external genitalia morphogenesis(GO:0035261)
6.9	48.2	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
6.9	172.1	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
6.9	20.6	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
6.9	109.7	GO:0048242	epinephrine secretion(GO:0048242)
6.9	68.6	GO:1900118	negative regulation of execution phase of apoptosis(GO:1900118)
6.8	41.1	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
6.8	27.3	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
6.8	34.0	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
6.8	27.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
6.8	20.4	GO:0036446	myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
6.8	13.6	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
6.8	20.3	GO:0036334	epidermal stem cell homeostasis(GO:0036334)
6.8	33.8	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
6.7	33.6	GO:0034472	snRNA 3'-end processing(GO:0034472)
6.7	26.9	GO:0009826	unidimensional cell growth(GO:0009826)
6.6	53.1	GO:1903232	melanosome assembly(GO:1903232)
6.6	6.6	GO:0002584	negative regulation of antigen processing and presentation(GO:0002578) negative regulation of antigen processing and presentation of peptide antigen(GO:0002584) regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
6.6	53.0	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
6.6	6.6	GO:0071865	regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
6.6	6.6	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
6.5	6.5	GO:0072528	pyrimidine-containing compound biosynthetic process(GO:0072528)
6.5	58.3	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
6.5	6.5	GO:0036297	interstrand cross-link repair(GO:0036297)
6.5	6.5	GO:0071220	response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
6.5	38.8	GO:0070827	chromatin maintenance(GO:0070827)
6.5	12.9	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
6.5	25.8	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
6.4	19.3	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
6.4	25.8	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
6.4	19.3	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
6.4	96.4	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
6.4	6.4	GO:0016476	regulation of embryonic cell shape(GO:0016476)
6.4	6.4	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
6.4	12.8	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
6.4	38.2	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
6.3	76.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
6.3	19.0	GO:0034635	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
6.3	6.3	GO:0009597	detection of virus(GO:0009597)
6.3	81.3	GO:0071044	histone mRNA catabolic process(GO:0071044)
6.2	31.2	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
6.2	6.2	GO:0033184	positive regulation of histone ubiquitination(GO:0033184)
6.2	37.0	GO:0051026	chiasma assembly(GO:0051026)
6.2	24.7	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
6.2	36.9	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
6.1	12.3	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
6.1	6.1	GO:0016539	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
6.1	30.6	GO:0016259	selenocysteine metabolic process(GO:0016259)
6.1	6.1	GO:0000492	box C/D snoRNP assembly(GO:0000492)
6.1	97.7	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
6.1	73.0	GO:0006012	galactose metabolic process(GO:0006012)
6.0	60.3	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
6.0	18.1	GO:0002143	tRNA wobble position uridine thiolation(GO:0002143)
6.0	18.0	GO:1903445	protein transport from ciliary membrane to plasma membrane(GO:1903445)
6.0	36.0	GO:0002517	T cell tolerance induction(GO:0002517)
6.0	17.9	GO:0061744	motor behavior(GO:0061744)
5.9	41.4	GO:0035879	plasma membrane lactate transport(GO:0035879)
5.9	47.3	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
5.9	11.8	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
5.9	123.7	GO:0070228	regulation of lymphocyte apoptotic process(GO:0070228)
5.9	29.4	GO:0050755	chemokine metabolic process(GO:0050755)
5.9	17.6	GO:1904401	cellular response to Thyroid stimulating hormone(GO:1904401)
5.8	17.4	GO:1904373	response to kainic acid(GO:1904373)
5.8	5.8	GO:0033182	regulation of histone ubiquitination(GO:0033182)
5.8	46.4	GO:0001842	neural fold formation(GO:0001842)
5.8	40.3	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
5.7	40.0	GO:2000399	negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
5.7	11.3	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
5.7	11.3	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
5.7	79.2	GO:0050434	positive regulation of viral transcription(GO:0050434)
5.6	185.1	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
5.6	16.8	GO:0070602	regulation of centromeric sister chromatid cohesion(GO:0070602)
5.6	28.0	GO:0015074	DNA integration(GO:0015074)
5.6	5.6	GO:0007260	tyrosine phosphorylation of STAT protein(GO:0007260)
5.6	11.2	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
5.6	16.7	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
5.6	22.3	GO:0071557	histone H3-K27 demethylation(GO:0071557)
5.6	44.5	GO:0016266	O-glycan processing(GO:0016266)
5.5	244.2	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
5.5	11.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
5.5	11.0	GO:1990823	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
5.5	27.4	GO:1904117	cellular response to vasopressin(GO:1904117)
5.5	163.7	GO:0033120	positive regulation of RNA splicing(GO:0033120)
5.4	16.3	GO:0035092	sperm chromatin condensation(GO:0035092)
5.4	10.9	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
5.4	21.7	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
5.4	10.8	GO:1990166	protein localization to site of double-strand break(GO:1990166)
5.4	10.8	GO:0070084	protein initiator methionine removal(GO:0070084)
5.4	32.4	GO:0007252	I-kappaB phosphorylation(GO:0007252)
5.4	16.2	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
5.4	32.2	GO:0090435	protein localization to nuclear envelope(GO:0090435)
5.4	37.6	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
5.4	208.7	GO:0010501	RNA secondary structure unwinding(GO:0010501)
5.3	42.7	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
5.3	16.0	GO:0010070	zygote asymmetric cell division(GO:0010070)
5.3	10.6	GO:2000424	regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
5.3	242.7	GO:0002260	lymphocyte homeostasis(GO:0002260)
5.3	10.5	GO:0045005	DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
5.3	10.5	GO:1904528	positive regulation of microtubule binding(GO:1904528)
5.3	47.4	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
5.3	26.3	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
5.2	5.2	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
5.2	26.2	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
5.2	26.1	GO:0033004	negative regulation of mast cell activation(GO:0033004)
5.2	67.9	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
5.2	5.2	GO:1905232	cellular response to L-glutamate(GO:1905232)
5.2	52.2	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
5.2	15.6	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
5.2	20.7	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
5.2	57.0	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
5.2	31.1	GO:1902570	protein localization to nucleolus(GO:1902570)
5.2	15.5	GO:0070650	actin filament bundle distribution(GO:0070650)
5.2	5.2	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
5.2	62.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
5.2	36.2	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
5.1	10.3	GO:0002215	defense response to nematode(GO:0002215)
5.1	10.3	GO:1903334	positive regulation of protein folding(GO:1903334)
5.1	30.7	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
5.0	25.2	GO:0030220	platelet formation(GO:0030220)
5.0	35.3	GO:0002183	cytoplasmic translational initiation(GO:0002183)
5.0	135.9	GO:0019731	antibacterial humoral response(GO:0019731)
5.0	20.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
5.0	25.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
5.0	35.1	GO:0006868	glutamine transport(GO:0006868)
5.0	20.0	GO:0034759	regulation of iron ion transmembrane transport(GO:0034759) negative regulation of iron ion transmembrane transport(GO:0034760) elastin biosynthetic process(GO:0051542)
5.0	84.9	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
5.0	59.9	GO:0035855	megakaryocyte development(GO:0035855)
5.0	29.9	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
5.0	99.4	GO:0006298	mismatch repair(GO:0006298)
4.9	24.7	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
4.9	4.9	GO:0070370	cellular heat acclimation(GO:0070370)
4.9	49.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
4.9	19.7	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
4.9	34.4	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
4.9	14.7	GO:1990785	response to water-immersion restraint stress(GO:1990785)
4.9	166.8	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
4.9	24.5	GO:0035278	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
4.9	53.9	GO:0051310	metaphase plate congression(GO:0051310)
4.8	4.8	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
4.8	4.8	GO:1904430	negative regulation of t-circle formation(GO:1904430)
4.8	14.5	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
4.8	19.3	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
4.8	14.3	GO:0051307	meiotic chromosome separation(GO:0051307)
4.8	33.3	GO:0034349	glial cell apoptotic process(GO:0034349)
4.8	23.8	GO:0035912	dorsal aorta morphogenesis(GO:0035912)
4.7	18.9	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
4.7	37.8	GO:0007021	tubulin complex assembly(GO:0007021)
4.7	61.2	GO:0032897	negative regulation of viral transcription(GO:0032897)
4.7	4.7	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
4.7	32.9	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
4.7	18.8	GO:0071386	cellular response to corticosterone stimulus(GO:0071386)
4.7	23.4	GO:2000780	negative regulation of double-strand break repair(GO:2000780)
4.7	42.1	GO:0016045	detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
4.6	88.2	GO:0006491	N-glycan processing(GO:0006491)
4.6	111.3	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022)
4.6	13.9	GO:0061073	ciliary body morphogenesis(GO:0061073)
4.6	124.9	GO:0007099	centriole replication(GO:0007099)
4.6	13.8	GO:0034421	post-translational protein acetylation(GO:0034421)
4.6	9.2	GO:0035600	tRNA methylthiolation(GO:0035600)
4.6	13.7	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
4.6	36.5	GO:0097068	response to thyroxine(GO:0097068)
4.6	4.6	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
4.6	18.2	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
4.6	4.6	GO:1901185	negative regulation of ERBB signaling pathway(GO:1901185)
4.5	13.6	GO:0009249	protein lipoylation(GO:0009249)
4.5	17.9	GO:0010266	response to vitamin B1(GO:0010266)
4.5	4.5	GO:0034769	basement membrane disassembly(GO:0034769)
4.5	13.4	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378)
4.4	35.6	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
4.4	13.3	GO:0014043	negative regulation of neuron maturation(GO:0014043)
4.4	185.9	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
4.4	8.8	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
4.4	13.2	GO:0006011	UDP-glucose metabolic process(GO:0006011)
4.4	17.6	GO:0044211	CTP salvage(GO:0044211)
4.4	8.8	GO:0020027	hemoglobin metabolic process(GO:0020027)
4.4	17.6	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
4.4	39.5	GO:0070933	histone H4 deacetylation(GO:0070933)
4.3	17.4	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
4.3	26.1	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
4.3	73.3	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
4.3	12.8	GO:1904211	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
4.2	42.5	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
4.2	4.2	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
4.2	12.7	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
4.2	12.7	GO:0018992	germ-line sex determination(GO:0018992)
4.2	12.6	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
4.2	21.0	GO:0022614	membrane to membrane docking(GO:0022614)
4.2	29.4	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
4.2	8.4	GO:0006433	prolyl-tRNA aminoacylation(GO:0006433)
4.2	46.0	GO:0045023	G0 to G1 transition(GO:0045023)
4.2	20.9	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
4.2	12.5	GO:0097298	regulation of nucleus size(GO:0097298)
4.1	12.4	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
4.1	8.3	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
4.1	16.4	GO:0031179	peptide modification(GO:0031179)
4.1	12.3	GO:0002681	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
4.1	4.1	GO:0032056	positive regulation of translation in response to stress(GO:0032056)
4.1	8.2	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
4.1	28.5	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
4.1	4.1	GO:0089709	histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
4.1	4.1	GO:0048298	regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
4.0	28.1	GO:0043476	endosome to melanosome transport(GO:0035646) pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
4.0	8.0	GO:2000574	regulation of microtubule motor activity(GO:2000574)
4.0	16.0	GO:0035963	cellular response to interleukin-13(GO:0035963)
4.0	16.0	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
4.0	123.6	GO:0002181	cytoplasmic translation(GO:0002181)
4.0	51.8	GO:0035067	negative regulation of histone acetylation(GO:0035067)
4.0	4.0	GO:0071245	cellular response to carbon monoxide(GO:0071245)
3.9	7.9	GO:0071503	response to heparin(GO:0071503)
3.9	11.8	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
3.9	35.1	GO:0090385	phagosome-lysosome fusion(GO:0090385)
3.9	19.4	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
3.9	7.8	GO:0009227	nucleotide-sugar catabolic process(GO:0009227)
3.9	3.9	GO:0061724	lipophagy(GO:0061724)
3.8	30.5	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
3.8	7.6	GO:0007356	thorax and anterior abdomen determination(GO:0007356)
3.8	11.4	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
3.8	11.4	GO:0001955	blood vessel maturation(GO:0001955)
3.8	15.1	GO:0097327	response to antineoplastic agent(GO:0097327)
3.8	7.6	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
3.8	22.7	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
3.8	3.8	GO:0000966	RNA 5'-end processing(GO:0000966)
3.8	26.4	GO:0043686	co-translational protein modification(GO:0043686)
3.7	3.7	GO:1904400	response to Thyroid stimulating hormone(GO:1904400)
3.7	14.8	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
3.7	18.4	GO:0016095	polyprenol catabolic process(GO:0016095)
3.7	18.4	GO:1903715	regulation of aerobic respiration(GO:1903715)
3.7	11.0	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
3.7	18.3	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
3.6	7.2	GO:0097037	heme export(GO:0097037)
3.6	7.2	GO:0060700	regulation of ribonuclease activity(GO:0060700)
3.6	3.6	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
3.6	10.8	GO:1903165	response to polycyclic arene(GO:1903165)
3.6	42.9	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
3.6	7.2	GO:0071929	alpha-tubulin acetylation(GO:0071929)
3.6	17.8	GO:0000733	DNA strand renaturation(GO:0000733)
3.6	298.5	GO:0043484	regulation of RNA splicing(GO:0043484)
3.5	7.1	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
3.5	10.6	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
3.5	42.2	GO:0032365	intracellular lipid transport(GO:0032365)
3.5	84.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
3.5	21.0	GO:1901072	glucosamine-containing compound catabolic process(GO:1901072)
3.5	10.5	GO:0045059	positive thymic T cell selection(GO:0045059)
3.5	17.5	GO:0051299	centrosome separation(GO:0051299)
3.5	17.4	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
3.5	139.0	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
3.5	27.7	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
3.5	6.9	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
3.5	24.2	GO:0007042	lysosomal lumen acidification(GO:0007042)
3.4	34.5	GO:0061088	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
3.4	24.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
3.4	10.3	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
3.4	34.3	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
3.4	3.4	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
3.4	17.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
3.4	47.8	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041)
3.4	20.3	GO:0002507	tolerance induction(GO:0002507)
3.4	10.1	GO:0072144	glomerular mesangial cell development(GO:0072144)
3.4	6.8	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
3.4	10.1	GO:1900060	negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
3.4	13.5	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
3.4	10.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
3.4	20.2	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
3.3	23.4	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
3.3	43.3	GO:0031268	pseudopodium organization(GO:0031268)
3.3	13.3	GO:0071802	negative regulation of podosome assembly(GO:0071802)
3.3	19.8	GO:0035330	regulation of hippo signaling(GO:0035330)
3.3	9.9	GO:0072344	rescue of stalled ribosome(GO:0072344)
3.3	13.1	GO:0071492	cellular response to UV-A(GO:0071492)
3.3	6.5	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
3.3	13.1	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
3.3	6.5	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
3.3	9.8	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
3.3	42.4	GO:0016180	snRNA processing(GO:0016180)
3.3	26.0	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
3.2	6.5	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
3.2	3.2	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
3.2	6.4	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
3.2	16.1	GO:1904044	response to aldosterone(GO:1904044)
3.2	16.1	GO:0006968	cellular defense response(GO:0006968)
3.2	9.6	GO:0021508	floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
3.2	57.7	GO:0051028	mRNA transport(GO:0051028)
3.2	3.2	GO:2000468	regulation of peroxidase activity(GO:2000468)
3.2	15.9	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
3.2	22.3	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
3.2	28.6	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
3.2	82.5	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
3.2	41.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
3.1	28.3	GO:0050832	defense response to fungus(GO:0050832)
3.1	9.4	GO:0016554	cytidine to uridine editing(GO:0016554)
3.1	6.3	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
3.1	15.6	GO:1901656	glycoside transport(GO:1901656)
3.1	24.9	GO:0010668	ectodermal cell differentiation(GO:0010668)
3.1	12.4	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
3.1	9.2	GO:0021571	rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571)
3.1	55.3	GO:0038092	nodal signaling pathway(GO:0038092)
3.1	9.2	GO:0008063	Toll signaling pathway(GO:0008063)
3.1	18.4	GO:0001731	formation of translation preinitiation complex(GO:0001731)
3.0	3.0	GO:0090037	positive regulation of protein kinase C signaling(GO:0090037)
3.0	36.6	GO:0072673	lamellipodium morphogenesis(GO:0072673)
3.0	9.1	GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
3.0	15.2	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
3.0	63.6	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
3.0	18.1	GO:0043970	histone H3-K9 acetylation(GO:0043970)
3.0	45.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
3.0	48.1	GO:0032611	interleukin-1 beta production(GO:0032611)
3.0	122.9	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
3.0	104.8	GO:0031047	gene silencing by RNA(GO:0031047)
3.0	9.0	GO:0060764	cell-cell signaling involved in mammary gland development(GO:0060764)
3.0	9.0	GO:0030576	Cajal body organization(GO:0030576)
3.0	8.9	GO:0006290	pyrimidine dimer repair(GO:0006290)
3.0	17.9	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
3.0	5.9	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
3.0	32.7	GO:0033260	nuclear DNA replication(GO:0033260)
3.0	3.0	GO:0072719	cellular response to cisplatin(GO:0072719)
3.0	5.9	GO:0032494	response to peptidoglycan(GO:0032494)
3.0	11.8	GO:0006312	mitotic recombination(GO:0006312)
3.0	3.0	GO:1903544	response to butyrate(GO:1903544)
2.9	26.5	GO:0060056	mammary gland involution(GO:0060056)
2.9	2.9	GO:0010934	macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935)
2.9	17.5	GO:0051014	actin filament severing(GO:0051014)
2.9	2.9	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
2.9	35.0	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
2.9	5.8	GO:0048014	Tie signaling pathway(GO:0048014)
2.9	98.6	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
2.9	5.8	GO:0039530	MDA-5 signaling pathway(GO:0039530)
2.9	17.3	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
2.9	11.5	GO:0035372	protein localization to microtubule(GO:0035372)
2.9	2.9	GO:0098707	ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
2.9	8.6	GO:0003415	chondrocyte hypertrophy(GO:0003415)
2.9	17.3	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
2.9	8.6	GO:1903896	positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
2.9	17.1	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
2.9	57.1	GO:0071346	cellular response to interferon-gamma(GO:0071346)
2.8	37.0	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
2.8	5.7	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
2.8	8.5	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
2.8	8.4	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
2.8	33.6	GO:0050872	white fat cell differentiation(GO:0050872)
2.8	2.8	GO:0071579	regulation of zinc ion transport(GO:0071579)
2.8	8.3	GO:0046016	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
2.7	5.4	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
2.7	16.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
2.7	5.4	GO:0051177	meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
2.7	46.0	GO:0046329	negative regulation of JNK cascade(GO:0046329)
2.7	21.5	GO:0034720	histone H3-K4 demethylation(GO:0034720)
2.7	16.0	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
2.7	354.5	GO:0008380	RNA splicing(GO:0008380)
2.6	15.9	GO:0010992	ubiquitin homeostasis(GO:0010992)
2.6	18.4	GO:0006477	protein sulfation(GO:0006477)
2.6	10.5	GO:0016115	isoprenoid catabolic process(GO:0008300) diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
2.6	115.2	GO:0043966	histone H3 acetylation(GO:0043966)
2.6	10.4	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
2.6	5.2	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
2.6	20.8	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
2.6	5.2	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
2.6	25.9	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
2.6	10.4	GO:0089700	protein kinase D signaling(GO:0089700)
2.6	2.6	GO:0048241	epinephrine transport(GO:0048241)
2.6	5.2	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
2.6	12.8	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
2.6	7.7	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
2.6	7.7	GO:0001682	tRNA 5'-leader removal(GO:0001682)
2.6	15.4	GO:0046325	negative regulation of glucose import(GO:0046325)
2.5	7.6	GO:0007398	ectoderm development(GO:0007398)
2.5	10.1	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
2.5	5.0	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
2.5	5.0	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
2.5	5.0	GO:0003342	proepicardium development(GO:0003342) septum transversum development(GO:0003343)
2.5	2.5	GO:0035622	intrahepatic bile duct development(GO:0035622)
2.5	5.0	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
2.5	7.4	GO:0060235	lens induction in camera-type eye(GO:0060235)
2.5	32.1	GO:0006289	nucleotide-excision repair(GO:0006289)
2.5	7.4	GO:0046333	octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
2.4	19.6	GO:0051382	kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
2.4	14.7	GO:0090179	regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
2.4	4.9	GO:0070227	lymphocyte apoptotic process(GO:0070227)
2.4	14.5	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
2.4	7.2	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
2.4	19.2	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
2.4	23.9	GO:0071803	positive regulation of podosome assembly(GO:0071803)
2.4	9.6	GO:0050869	negative regulation of B cell activation(GO:0050869)
2.4	33.5	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
2.4	16.7	GO:0006957	complement activation, alternative pathway(GO:0006957)
2.4	7.2	GO:0048102	autophagic cell death(GO:0048102)
2.4	33.3	GO:0046415	urate metabolic process(GO:0046415)
2.4	2.4	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
2.4	7.1	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
2.4	7.1	GO:0006004	fucose metabolic process(GO:0006004)
2.4	2.4	GO:0097286	iron ion import(GO:0097286)
2.4	75.2	GO:0006505	GPI anchor metabolic process(GO:0006505)
2.4	7.1	GO:0061450	trophoblast cell migration(GO:0061450)
2.3	9.4	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
2.3	9.4	GO:2000811	negative regulation of anoikis(GO:2000811)
2.3	7.0	GO:0046380	N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380) glucosamine-containing compound biosynthetic process(GO:1901073)
2.3	4.6	GO:0016240	autophagosome docking(GO:0016240)
2.3	4.6	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
2.3	9.3	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
2.3	23.2	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
2.3	48.6	GO:0019835	cytolysis(GO:0019835)
2.3	23.0	GO:0015671	oxygen transport(GO:0015671)
2.3	2.3	GO:0031620	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
2.3	6.9	GO:0019805	quinolinate biosynthetic process(GO:0019805)
2.3	13.7	GO:0071850	mitotic cell cycle arrest(GO:0071850)
2.3	31.7	GO:0001913	T cell mediated cytotoxicity(GO:0001913)
2.3	6.8	GO:0030210	heparin biosynthetic process(GO:0030210)
2.2	9.0	GO:0071718	sodium-independent icosanoid transport(GO:0071718)
2.2	80.5	GO:0051225	spindle assembly(GO:0051225)
2.2	13.4	GO:0042559	pteridine-containing compound biosynthetic process(GO:0042559)
2.2	8.8	GO:0035562	negative regulation of chromatin binding(GO:0035562)
2.2	4.4	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
2.2	6.6	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
2.2	13.2	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
2.2	19.8	GO:1904353	regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
2.2	4.4	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
2.2	63.1	GO:0050868	negative regulation of T cell activation(GO:0050868)
2.2	30.3	GO:0043968	histone H2A acetylation(GO:0043968)
2.2	2.2	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
2.1	89.4	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
2.1	6.4	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
2.1	10.6	GO:0038203	TORC2 signaling(GO:0038203)
2.1	4.2	GO:0051660	establishment of centrosome localization(GO:0051660)
2.1	19.1	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
2.1	4.2	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
2.1	12.7	GO:0030852	regulation of granulocyte differentiation(GO:0030852)
2.1	6.3	GO:0071409	cellular response to cycloheximide(GO:0071409)
2.1	31.6	GO:0032814	regulation of natural killer cell activation(GO:0032814)
2.1	18.9	GO:0032506	cytokinetic process(GO:0032506)
2.1	8.4	GO:0032486	Rap protein signal transduction(GO:0032486)
2.1	25.2	GO:0044030	regulation of DNA methylation(GO:0044030)
2.1	46.1	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
2.1	8.4	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
2.1	14.6	GO:0045947	negative regulation of translational initiation(GO:0045947)
2.1	12.5	GO:0019985	translesion synthesis(GO:0019985)
2.1	43.6	GO:0002819	regulation of adaptive immune response(GO:0002819)
2.1	195.2	GO:0090305	nucleic acid phosphodiester bond hydrolysis(GO:0090305)
2.1	2.1	GO:0035754	B cell chemotaxis(GO:0035754)
2.1	4.2	GO:0048539	bone marrow development(GO:0048539)
2.1	4.1	GO:0070828	heterochromatin organization(GO:0070828)
2.1	4.1	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
2.1	61.8	GO:0000724	double-strand break repair via homologous recombination(GO:0000724)
2.1	10.3	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
2.0	8.2	GO:0006741	NADP biosynthetic process(GO:0006741)
2.0	16.4	GO:0035518	histone H2A monoubiquitination(GO:0035518)
2.0	2.0	GO:0031161	phosphatidylinositol catabolic process(GO:0031161)
2.0	28.5	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627)
2.0	14.3	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
2.0	8.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
2.0	73.1	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
2.0	28.4	GO:0001675	acrosome assembly(GO:0001675)
2.0	2.0	GO:0015966	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
2.0	10.1	GO:0060561	apoptotic process involved in morphogenesis(GO:0060561)
2.0	6.1	GO:1901423	response to benzene(GO:1901423)
2.0	8.0	GO:1901031	regulation of response to reactive oxygen species(GO:1901031)
2.0	14.0	GO:0046884	follicle-stimulating hormone secretion(GO:0046884)
2.0	6.0	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
2.0	29.8	GO:0006691	leukotriene metabolic process(GO:0006691)
2.0	6.0	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
2.0	4.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
2.0	17.6	GO:0072015	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
2.0	11.7	GO:0090527	actin filament reorganization(GO:0090527)
2.0	31.3	GO:1903205	regulation of hydrogen peroxide-induced cell death(GO:1903205)
1.9	7.8	GO:0060455	negative regulation of gastric acid secretion(GO:0060455)
1.9	27.2	GO:0072698	protein localization to microtubule cytoskeleton(GO:0072698)
1.9	5.8	GO:0009838	abscission(GO:0009838)
1.9	7.8	GO:0019372	lipoxygenase pathway(GO:0019372)
1.9	9.7	GO:0019521	aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
1.9	9.7	GO:0001582	detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
1.9	7.7	GO:0042635	positive regulation of hair cycle(GO:0042635)
1.9	9.6	GO:0031584	activation of phospholipase D activity(GO:0031584)
1.9	1.9	GO:0090166	Golgi disassembly(GO:0090166)
1.9	13.4	GO:0055070	copper ion homeostasis(GO:0055070)
1.9	13.3	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
1.9	9.4	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
1.9	15.0	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
1.9	24.3	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
1.9	7.5	GO:2001028	positive regulation of endothelial cell chemotaxis(GO:2001028)
1.9	7.5	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
1.8	3.7	GO:0045060	negative thymic T cell selection(GO:0045060)
1.8	3.7	GO:0070914	UV-damage excision repair(GO:0070914)
1.8	3.7	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
1.8	12.9	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
1.8	7.4	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.8	34.7	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
1.8	5.5	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
1.8	1.8	GO:0051974	negative regulation of telomerase activity(GO:0051974)
1.8	3.6	GO:0048341	paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
1.8	3.6	GO:1901858	regulation of mitochondrial DNA metabolic process(GO:1901858)
1.8	7.2	GO:0060005	vestibular reflex(GO:0060005)
1.8	8.9	GO:0042908	xenobiotic transport(GO:0042908)
1.8	42.9	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.8	7.1	GO:0006172	ADP biosynthetic process(GO:0006172)
1.8	7.1	GO:0046512	sphingosine biosynthetic process(GO:0046512)
1.8	12.4	GO:0036065	fucosylation(GO:0036065)
1.8	5.3	GO:0002327	immature B cell differentiation(GO:0002327)
1.8	7.1	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
1.8	5.3	GO:0032218	riboflavin transport(GO:0032218)
1.8	17.6	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
1.8	149.0	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
1.7	15.7	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
1.7	3.5	GO:0042732	D-xylose metabolic process(GO:0042732)
1.7	3.5	GO:0016441	posttranscriptional gene silencing(GO:0016441)
1.7	3.5	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
1.7	5.2	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.7	15.4	GO:0052697	xenobiotic glucuronidation(GO:0052697)
1.7	5.1	GO:0060613	fat pad development(GO:0060613)
1.7	10.2	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
1.7	5.1	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
1.7	28.7	GO:0006206	pyrimidine nucleobase metabolic process(GO:0006206)
1.7	15.2	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
1.7	5.0	GO:0043388	positive regulation of DNA binding(GO:0043388)
1.7	3.4	GO:0042636	negative regulation of hair cycle(GO:0042636)
1.7	5.0	GO:0035964	COPI-coated vesicle budding(GO:0035964)
1.7	18.4	GO:0010960	magnesium ion homeostasis(GO:0010960)
1.7	3.3	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
1.6	37.9	GO:0032008	positive regulation of TOR signaling(GO:0032008)
1.6	3.3	GO:0040016	embryonic cleavage(GO:0040016)
1.6	21.2	GO:0006284	base-excision repair(GO:0006284)
1.6	3.3	GO:0022616	DNA strand elongation(GO:0022616)
1.6	11.4	GO:0009235	cobalamin metabolic process(GO:0009235)
1.6	51.7	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
1.6	14.5	GO:0070932	histone H3 deacetylation(GO:0070932)
1.6	11.3	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
1.6	6.4	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
1.6	4.8	GO:0072643	interferon-gamma secretion(GO:0072643)
1.6	12.7	GO:0007052	mitotic spindle organization(GO:0007052)
1.6	3.2	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
1.6	9.3	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
1.5	26.2	GO:1902808	positive regulation of cell cycle G1/S phase transition(GO:1902808)
1.5	1.5	GO:1902590	viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
1.5	10.6	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
1.5	6.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.5	3.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.5	6.0	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
1.5	19.5	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
1.5	16.3	GO:0016578	histone deubiquitination(GO:0016578)
1.5	7.4	GO:0019934	cGMP-mediated signaling(GO:0019934)
1.5	3.0	GO:0043129	surfactant homeostasis(GO:0043129)
1.5	51.8	GO:0050912	detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
1.5	8.9	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
1.5	42.7	GO:0070207	protein homotrimerization(GO:0070207)
1.5	16.1	GO:0035455	response to interferon-alpha(GO:0035455)
1.5	2.9	GO:0000012	single strand break repair(GO:0000012)
1.5	5.8	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
1.4	4.3	GO:0090399	replicative senescence(GO:0090399)
1.4	4.3	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
1.4	15.6	GO:0007567	parturition(GO:0007567)
1.4	11.3	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.4	8.5	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
1.4	8.4	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
1.4	4.2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
1.4	4.2	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
1.4	16.8	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
1.4	5.6	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
1.4	1.4	GO:0030167	proteoglycan catabolic process(GO:0030167) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
1.4	8.4	GO:0048227	plasma membrane to endosome transport(GO:0048227)
1.4	13.9	GO:0097205	renal filtration(GO:0097205)
1.4	5.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.4	9.6	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
1.4	16.4	GO:0006895	Golgi to endosome transport(GO:0006895)
1.4	12.2	GO:0030168	platelet activation(GO:0030168)
1.3	12.1	GO:0071280	cellular response to copper ion(GO:0071280)
1.3	20.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
1.3	18.6	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
1.3	5.3	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
1.3	2.6	GO:0097341	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
1.3	13.0	GO:0071353	cellular response to interleukin-4(GO:0071353)
1.3	3.9	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
1.3	2.6	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
1.3	40.1	GO:0071897	DNA biosynthetic process(GO:0071897)
1.3	2.6	GO:0007289	spermatid nucleus differentiation(GO:0007289)
1.3	42.3	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
1.3	24.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
1.3	97.2	GO:0090630	activation of GTPase activity(GO:0090630)
1.3	3.8	GO:0034969	histone arginine methylation(GO:0034969)
1.3	11.3	GO:0007603	phototransduction, visible light(GO:0007603)
1.3	7.6	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
1.3	54.1	GO:0006397	mRNA processing(GO:0006397)
1.2	5.0	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
1.2	24.9	GO:0097421	liver regeneration(GO:0097421)
1.2	3.7	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
1.2	46.9	GO:0006413	translational initiation(GO:0006413)
1.2	37.0	GO:0000070	mitotic sister chromatid segregation(GO:0000070)
1.2	22.2	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
1.2	7.4	GO:0007143	female meiotic division(GO:0007143)
1.2	12.3	GO:2000772	regulation of cellular senescence(GO:2000772)
1.2	17.1	GO:0032608	interferon-beta production(GO:0032608)
1.2	3.7	GO:0035720	intraciliary anterograde transport(GO:0035720)
1.2	9.8	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.2	7.3	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
1.2	3.6	GO:0070307	lens fiber cell development(GO:0070307)
1.2	2.4	GO:0070638	nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
1.2	1.2	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
1.2	11.8	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.2	2.4	GO:0048850	hypophysis morphogenesis(GO:0048850)
1.2	3.5	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
1.2	7.1	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
1.2	7.0	GO:0030321	transepithelial chloride transport(GO:0030321)
1.2	5.8	GO:0060770	epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
1.2	4.7	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
1.2	3.5	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
1.2	2.3	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
1.2	8.1	GO:0008343	adult feeding behavior(GO:0008343)
1.2	3.5	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
1.2	3.5	GO:0042891	antibiotic transport(GO:0042891)
1.1	1.1	GO:0009436	glyoxylate catabolic process(GO:0009436)
1.1	10.3	GO:0035269	protein O-linked mannosylation(GO:0035269)
1.1	6.8	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
1.1	3.4	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.1	6.7	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
1.1	5.6	GO:0060216	definitive hemopoiesis(GO:0060216)
1.1	2.2	GO:0050828	regulation of liquid surface tension(GO:0050828)
1.1	4.4	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
1.1	7.7	GO:0030502	negative regulation of bone mineralization(GO:0030502)
1.1	16.3	GO:0007602	phototransduction(GO:0007602)
1.1	6.5	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
1.1	3.3	GO:0035162	embryonic hemopoiesis(GO:0035162)
1.1	23.8	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
1.1	5.4	GO:0010889	regulation of sequestering of triglyceride(GO:0010889)
1.1	2.2	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
1.1	5.4	GO:0043418	homocysteine catabolic process(GO:0043418)
1.1	7.5	GO:0034498	early endosome to Golgi transport(GO:0034498)
1.1	3.2	GO:0051352	negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
1.1	6.3	GO:0045582	positive regulation of T cell differentiation(GO:0045582)
1.1	2.1	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
1.1	4.2	GO:0072520	seminiferous tubule development(GO:0072520)
1.0	7.3	GO:2000696	regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
1.0	6.2	GO:0048820	hair follicle maturation(GO:0048820)
1.0	5.2	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
1.0	2.1	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
1.0	3.1	GO:0044380	protein localization to cytoskeleton(GO:0044380)
1.0	5.2	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
1.0	318.7	GO:0043547	positive regulation of GTPase activity(GO:0043547)
1.0	5.1	GO:0048251	elastic fiber assembly(GO:0048251)
1.0	16.4	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313)
1.0	9.2	GO:0070206	protein trimerization(GO:0070206)
1.0	20.3	GO:0032964	collagen biosynthetic process(GO:0032964)
1.0	17.2	GO:0006471	protein ADP-ribosylation(GO:0006471)
1.0	4.0	GO:0008355	olfactory learning(GO:0008355)
1.0	10.1	GO:0032329	serine transport(GO:0032329)
1.0	4.0	GO:0002934	desmosome organization(GO:0002934)
1.0	6.9	GO:0070734	histone H3-K27 methylation(GO:0070734)
1.0	5.0	GO:0060430	lung saccule development(GO:0060430)
1.0	3.0	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
1.0	17.6	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
1.0	4.9	GO:0070162	adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
1.0	2.9	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.9	1.9	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.9	19.6	GO:2000179	positive regulation of neural precursor cell proliferation(GO:2000179)
0.9	0.9	GO:0014908	myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.9	1.9	GO:0019614	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.9	5.6	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.9	1.8	GO:0090500	endocardial cushion to mesenchymal transition(GO:0090500)
0.9	4.6	GO:0034214	protein hexamerization(GO:0034214)
0.9	1.8	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.9	4.5	GO:0035825	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.9	5.4	GO:0030225	macrophage differentiation(GO:0030225)
0.9	1.8	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.9	16.0	GO:0010039	response to iron ion(GO:0010039)
0.9	3.6	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.9	6.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.9	2.6	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.9	15.6	GO:0018023	peptidyl-lysine trimethylation(GO:0018023)
0.9	0.9	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.8	1.7	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.8	11.7	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.8	5.0	GO:0034341	response to interferon-gamma(GO:0034341)
0.8	9.0	GO:1901799	negative regulation of proteasomal protein catabolic process(GO:1901799)
0.8	2.5	GO:0001510	RNA methylation(GO:0001510)
0.8	3.3	GO:1904717	regulation of AMPA glutamate receptor clustering(GO:1904717)
0.8	18.1	GO:0045727	positive regulation of translation(GO:0045727)
0.8	9.8	GO:0045056	transcytosis(GO:0045056)
0.8	5.7	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.8	56.1	GO:0019827	stem cell population maintenance(GO:0019827)
0.8	4.1	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.8	24.2	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.8	10.5	GO:0000281	mitotic cytokinesis(GO:0000281)
0.8	5.6	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.8	6.3	GO:0051013	microtubule severing(GO:0051013)
0.8	0.8	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.8	8.5	GO:0006020	inositol metabolic process(GO:0006020)
0.8	6.9	GO:0061436	establishment of skin barrier(GO:0061436)
0.8	13.9	GO:0006220	pyrimidine nucleotide metabolic process(GO:0006220)
0.8	4.6	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.8	3.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.8	1.5	GO:0051935	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.8	40.9	GO:0006260	DNA replication(GO:0006260)
0.8	9.8	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.8	9.8	GO:2001240	negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.8	24.9	GO:0000186	activation of MAPKK activity(GO:0000186)
0.8	4.5	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.7	2.2	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.7	4.5	GO:0006545	glycine biosynthetic process(GO:0006545)
0.7	3.7	GO:0006999	nuclear pore organization(GO:0006999)
0.7	1.5	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.7	3.7	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.7	5.8	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
0.7	5.1	GO:0035307	positive regulation of protein dephosphorylation(GO:0035307)
0.7	7.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.7	3.6	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.7	6.5	GO:0000578	embryonic axis specification(GO:0000578)
0.7	10.8	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.7	11.5	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.7	1.4	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.7	7.9	GO:0006809	nitric oxide biosynthetic process(GO:0006809)
0.7	2.9	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.7	10.7	GO:0006958	complement activation, classical pathway(GO:0006958)
0.7	0.7	GO:1904835	vestibulocochlear nerve structural organization(GO:0021649) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551) ganglion morphogenesis(GO:0061552) facioacoustic ganglion development(GO:1903375) dorsal root ganglion morphogenesis(GO:1904835) dorsal root ganglion development(GO:1990791)
0.7	2.1	GO:0051414	response to cortisol(GO:0051414)
0.7	0.7	GO:1902415	regulation of mRNA binding(GO:1902415) positive regulation of mRNA binding(GO:1902416)
0.7	2.8	GO:0033131	regulation of glucokinase activity(GO:0033131)
0.7	0.7	GO:0000212	meiotic spindle organization(GO:0000212)
0.7	4.1	GO:0033005	positive regulation of mast cell activation(GO:0033005)
0.7	27.5	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.6	1.3	GO:0032757	positive regulation of interleukin-8 production(GO:0032757)
0.6	1.3	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.6	4.4	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.6	10.7	GO:0071901	negative regulation of protein serine/threonine kinase activity(GO:0071901)
0.6	2.5	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.6	3.1	GO:0002548	monocyte chemotaxis(GO:0002548)
0.6	1.8	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.6	3.7	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.6	4.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.6	6.0	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.6	6.0	GO:0006360	transcription from RNA polymerase I promoter(GO:0006360)
0.6	3.0	GO:0034389	lipid particle organization(GO:0034389)
0.6	1.8	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.6	7.1	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.6	2.9	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.6	2.3	GO:0030953	astral microtubule organization(GO:0030953)
0.6	6.8	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.6	0.6	GO:0015780	nucleotide-sugar transport(GO:0015780)
0.6	6.7	GO:0000075	cell cycle checkpoint(GO:0000075)
0.6	1.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.6	1.7	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.5	6.6	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.5	3.8	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.5	1.6	GO:0015811	L-cystine transport(GO:0015811)
0.5	14.9	GO:0042254	ribosome biogenesis(GO:0042254)
0.5	3.6	GO:0006907	pinocytosis(GO:0006907)
0.5	1.6	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.5	3.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.5	1.5	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.5	2.1	GO:0033227	dsRNA transport(GO:0033227)
0.5	7.2	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.5	3.1	GO:0002377	immunoglobulin production(GO:0002377)
0.5	5.5	GO:0097320	membrane tubulation(GO:0097320)
0.5	2.5	GO:1901142	insulin processing(GO:0030070) insulin metabolic process(GO:1901142)
0.5	2.0	GO:0019471	4-hydroxyproline metabolic process(GO:0019471)
0.5	2.9	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.5	1.9	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.5	1.9	GO:1903575	cornified envelope assembly(GO:1903575)
0.5	3.7	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.5	5.5	GO:0071482	cellular response to light stimulus(GO:0071482)
0.4	6.7	GO:0009112	nucleobase metabolic process(GO:0009112)
0.4	5.3	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
0.4	2.2	GO:0002251	organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.4	49.4	GO:0006913	nucleocytoplasmic transport(GO:0006913)
0.4	2.5	GO:0002070	epithelial cell maturation(GO:0002070)
0.4	0.4	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.4	0.8	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.4	4.5	GO:2001022	positive regulation of response to DNA damage stimulus(GO:2001022)
0.4	4.5	GO:0033327	Leydig cell differentiation(GO:0033327)
0.4	1.6	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.4	0.4	GO:0007227	signal transduction downstream of smoothened(GO:0007227) positive regulation of hh target transcription factor activity(GO:0007228)
0.4	2.8	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.4	1.2	GO:0051684	maintenance of Golgi location(GO:0051684)
0.4	3.8	GO:0007140	male meiosis(GO:0007140)
0.4	0.7	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.4	0.4	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.3	3.5	GO:2000648	positive regulation of stem cell proliferation(GO:2000648)
0.3	0.7	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.3	0.7	GO:0042533	tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534)
0.3	5.0	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.3	2.9	GO:0045682	regulation of epidermis development(GO:0045682)
0.3	1.2	GO:0003360	brainstem development(GO:0003360)
0.3	1.5	GO:0001927	exocyst assembly(GO:0001927)
0.3	0.3	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.3	1.2	GO:0032919	spermine acetylation(GO:0032919)
0.3	1.5	GO:0035357	peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.3	1.8	GO:0018342	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.3	1.2	GO:0042574	retinal metabolic process(GO:0042574)
0.3	0.9	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3	1.4	GO:0015677	copper ion import(GO:0015677)
0.3	0.8	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3	1.7	GO:0097264	self proteolysis(GO:0097264)
0.3	0.3	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.3	0.8	GO:1905048	regulation of metallopeptidase activity(GO:1905048)
0.3	1.3	GO:0022417	protein maturation by protein folding(GO:0022417)
0.2	1.0	GO:0060467	negative regulation of fertilization(GO:0060467)
0.2	1.5	GO:0015860	purine nucleoside transmembrane transport(GO:0015860)
0.2	1.7	GO:0050000	chromosome localization(GO:0050000)
0.2	1.0	GO:0048252	lauric acid metabolic process(GO:0048252)
0.2	6.4	GO:0001541	ovarian follicle development(GO:0001541)
0.2	0.9	GO:1903826	arginine transmembrane transport(GO:1903826)
0.2	0.5	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.2	13.3	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.2	3.4	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.2	1.2	GO:0010165	response to X-ray(GO:0010165)
0.2	0.6	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	0.5	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2	0.2	GO:0061056	sclerotome development(GO:0061056)
0.2	0.2	GO:0036337	Fas signaling pathway(GO:0036337)
0.2	0.8	GO:0015886	heme transport(GO:0015886)
0.2	7.3	GO:0034470	ncRNA processing(GO:0034470)
0.2	0.6	GO:0043030	regulation of macrophage activation(GO:0043030)
0.2	1.4	GO:0015695	organic cation transport(GO:0015695)
0.2	2.1	GO:1902571	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.2	1.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.6	GO:0051958	methotrexate transport(GO:0051958)
0.1	0.9	GO:0001522	pseudouridine synthesis(GO:0001522)
0.1	0.3	GO:0009751	response to salicylic acid(GO:0009751)
0.1	2.9	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.1	1.5	GO:0050873	brown fat cell differentiation(GO:0050873)
0.1	0.9	GO:0006833	water transport(GO:0006833)
0.1	1.4	GO:0048286	lung alveolus development(GO:0048286)
0.1	0.7	GO:0098703	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1	1.4	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.1	0.9	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1	1.2	GO:0032465	regulation of cytokinesis(GO:0032465)
0.1	0.6	GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1	0.1	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1	0.3	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1	0.1	GO:0010870	positive regulation of receptor biosynthetic process(GO:0010870) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0	0.0	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.2	GO:0007097	nuclear migration(GO:0007097)
0.0	0.2	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	0.0	GO:0070175	positive regulation of enamel mineralization(GO:0070175)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
49.1	392.7	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
42.1	42.1	GO:0045298	tubulin complex(GO:0045298)
36.8	110.4	GO:0030690	Noc1p-Noc2p complex(GO:0030690)
35.2	105.5	GO:0044609	DBIRD complex(GO:0044609)
34.3	137.0	GO:0019815	B cell receptor complex(GO:0019815)
33.7	101.1	GO:0035101	FACT complex(GO:0035101)
30.0	30.0	GO:0097169	AIM2 inflammasome complex(GO:0097169)
29.0	260.7	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
25.7	102.6	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
24.2	217.4	GO:0042101	T cell receptor complex(GO:0042101)
23.5	47.0	GO:0072557	IPAF inflammasome complex(GO:0072557)
22.8	365.4	GO:0042613	MHC class II protein complex(GO:0042613)
22.0	175.9	GO:0044194	cytolytic granule(GO:0044194)
21.5	64.4	GO:0000811	GINS complex(GO:0000811)
21.4	64.3	GO:0033186	CAF-1 complex(GO:0033186)
21.3	85.3	GO:0032299	ribonuclease H2 complex(GO:0032299)
21.2	126.9	GO:0032133	chromosome passenger complex(GO:0032133)
19.9	139.3	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
19.6	98.2	GO:0034455	t-UTP complex(GO:0034455)
18.7	168.4	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
18.3	146.4	GO:0000796	condensin complex(GO:0000796)
17.9	628.2	GO:0001772	immunological synapse(GO:0001772)
16.9	50.6	GO:0031262	Ndc80 complex(GO:0031262)
16.7	200.7	GO:0005687	U4 snRNP(GO:0005687)
16.1	48.4	GO:0032173	septin collar(GO:0032173)
15.8	126.5	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
15.4	46.1	GO:0031680	G-protein beta/gamma-subunit complex(GO:0031680)
15.1	166.0	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
14.8	44.3	GO:0071001	U4/U6 snRNP(GO:0071001)
14.8	59.0	GO:0000444	MIS12/MIND type complex(GO:0000444)
14.8	103.3	GO:0001652	granular component(GO:0001652)
14.1	56.4	GO:0005846	nuclear cap binding complex(GO:0005846)
14.1	183.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
13.5	376.8	GO:0000788	nuclear nucleosome(GO:0000788)
13.1	52.5	GO:0018444	translation release factor complex(GO:0018444)
13.1	39.3	GO:0097124	cyclin A2-CDK2 complex(GO:0097124)
13.1	26.2	GO:0030125	clathrin vesicle coat(GO:0030125)
13.0	65.2	GO:0048476	Holliday junction resolvase complex(GO:0048476)
12.9	90.4	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
12.7	38.2	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
12.0	311.1	GO:0030687	preribosome, large subunit precursor(GO:0030687)
11.8	58.9	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
11.4	11.4	GO:0001740	Barr body(GO:0001740)
11.4	137.0	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
11.4	34.1	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
11.1	66.3	GO:0030289	protein phosphatase 4 complex(GO:0030289)
10.9	87.0	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
10.5	10.5	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
10.5	21.0	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
10.4	52.2	GO:0098536	deuterosome(GO:0098536)
10.1	50.4	GO:0044530	supraspliceosomal complex(GO:0044530)
10.0	40.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
10.0	89.9	GO:0042555	MCM complex(GO:0042555)
10.0	59.9	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
9.8	29.5	GO:0061574	ASAP complex(GO:0061574)
9.8	97.6	GO:0031080	nuclear pore outer ring(GO:0031080)
9.5	57.0	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
9.3	74.7	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
9.3	46.4	GO:0097165	nuclear stress granule(GO:0097165)
9.2	36.8	GO:0097149	centralspindlin complex(GO:0097149)
9.0	27.0	GO:0060187	cell pole(GO:0060187)
8.8	61.8	GO:0043203	axon hillock(GO:0043203)
8.8	43.8	GO:0031085	BLOC-3 complex(GO:0031085)
8.7	34.9	GO:0097427	microtubule bundle(GO:0097427)
8.6	154.8	GO:0042589	zymogen granule membrane(GO:0042589)
8.5	111.1	GO:0005686	U2 snRNP(GO:0005686)
8.5	93.7	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
8.4	59.0	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
8.4	33.7	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
8.3	624.8	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
8.2	81.8	GO:0097433	dense body(GO:0097433)
8.2	40.8	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
8.1	56.9	GO:0005688	U6 snRNP(GO:0005688)
8.0	24.0	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
7.8	31.2	GO:0097342	ripoptosome(GO:0097342)
7.8	39.0	GO:0097443	sorting endosome(GO:0097443)
7.8	23.3	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
7.8	15.5	GO:0070578	RISC-loading complex(GO:0070578)
7.7	123.1	GO:0042612	MHC class I protein complex(GO:0042612)
7.6	37.9	GO:0043293	apoptosome(GO:0043293)
7.3	682.7	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
7.2	173.6	GO:0032040	small-subunit processome(GO:0032040)
7.2	14.4	GO:0016342	catenin complex(GO:0016342)
7.2	21.6	GO:0071564	npBAF complex(GO:0071564)
7.2	71.9	GO:0043020	NADPH oxidase complex(GO:0043020)
7.2	42.9	GO:0036396	MIS complex(GO:0036396)
7.2	21.5	GO:0071438	invadopodium membrane(GO:0071438)
7.1	7.1	GO:0055087	Ski complex(GO:0055087)
7.0	55.8	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
6.9	48.3	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
6.9	61.9	GO:0071004	U2-type prespliceosome(GO:0071004)
6.8	34.2	GO:0043625	delta DNA polymerase complex(GO:0043625)
6.6	46.1	GO:0042825	TAP complex(GO:0042825)
6.6	210.3	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
6.5	32.5	GO:0061689	tricellular tight junction(GO:0061689)
6.5	91.0	GO:0031091	platelet alpha granule(GO:0031091)
6.5	90.9	GO:0005689	U12-type spliceosomal complex(GO:0005689)
6.4	51.5	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
6.4	102.8	GO:0070938	contractile ring(GO:0070938)
6.4	38.5	GO:0070847	core mediator complex(GO:0070847)
6.4	19.1	GO:0044611	nuclear pore inner ring(GO:0044611)
6.3	361.6	GO:0005657	replication fork(GO:0005657)
6.3	405.9	GO:0005871	kinesin complex(GO:0005871)
6.3	25.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
6.3	88.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
6.3	18.8	GO:0097413	Lewy body(GO:0097413)
6.3	106.4	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
6.1	79.7	GO:0072687	meiotic spindle(GO:0072687)
6.1	12.2	GO:0070876	SOSS complex(GO:0070876)
6.1	79.2	GO:0000801	central element(GO:0000801)
6.1	66.6	GO:0097526	spliceosomal tri-snRNP complex(GO:0097526)
6.0	30.2	GO:0000974	Prp19 complex(GO:0000974)
6.0	41.8	GO:0030688	preribosome, small subunit precursor(GO:0030688)
5.9	47.5	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
5.9	11.8	GO:0000346	transcription export complex(GO:0000346)
5.9	23.4	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
5.8	439.3	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
5.5	60.7	GO:0042588	zymogen granule(GO:0042588)
5.5	55.2	GO:0070652	HAUS complex(GO:0070652)
5.5	16.5	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
5.5	16.4	GO:0005760	gamma DNA polymerase complex(GO:0005760)
5.4	48.2	GO:0070419	nonhomologous end joining complex(GO:0070419)
5.4	53.5	GO:0070187	telosome(GO:0070187)
5.3	138.4	GO:0001891	phagocytic cup(GO:0001891)
5.3	53.2	GO:0044613	nuclear pore central transport channel(GO:0044613)
5.3	31.8	GO:0030896	checkpoint clamp complex(GO:0030896)
5.3	10.6	GO:1990907	beta-catenin-TCF complex(GO:1990907)
5.3	47.4	GO:0031209	SCAR complex(GO:0031209)
5.3	10.5	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
5.2	15.7	GO:0070421	DNA ligase III-XRCC1 complex(GO:0070421)
5.2	161.7	GO:0030131	clathrin adaptor complex(GO:0030131)
5.2	20.8	GO:0001405	presequence translocase-associated import motor(GO:0001405)
5.2	62.4	GO:0035631	CD40 receptor complex(GO:0035631)
5.1	10.3	GO:0070449	elongin complex(GO:0070449)
5.1	45.8	GO:0031616	spindle pole centrosome(GO:0031616)
5.1	1499.6	GO:0009897	external side of plasma membrane(GO:0009897)
5.0	15.1	GO:1902560	GMP reductase complex(GO:1902560)
5.0	25.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
5.0	20.0	GO:0000938	GARP complex(GO:0000938)
5.0	148.7	GO:0000777	condensed chromosome kinetochore(GO:0000777)
4.9	4.9	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
4.8	29.0	GO:0042382	paraspeckles(GO:0042382)
4.8	9.6	GO:0032389	MutLalpha complex(GO:0032389)
4.8	33.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
4.7	18.8	GO:0002947	tumor necrosis factor receptor superfamily complex(GO:0002947)
4.7	4.7	GO:0042827	platelet dense granule membrane(GO:0031088) platelet dense granule(GO:0042827)
4.6	4.6	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
4.6	23.2	GO:0035061	interchromatin granule(GO:0035061)
4.5	18.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
4.5	67.2	GO:0001741	XY body(GO:0001741)
4.5	4.5	GO:0070552	BRISC complex(GO:0070552)
4.4	57.6	GO:0032433	filopodium tip(GO:0032433)
4.4	8.8	GO:1990423	RZZ complex(GO:1990423)
4.3	8.7	GO:0070821	tertiary granule membrane(GO:0070821)
4.3	47.7	GO:0031527	filopodium membrane(GO:0031527)
4.3	56.1	GO:0030914	STAGA complex(GO:0030914)
4.3	8.6	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
4.3	17.1	GO:0033553	rDNA heterochromatin(GO:0033553)
4.3	17.0	GO:0035339	SPOTS complex(GO:0035339)
4.2	16.9	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
4.2	16.9	GO:0044299	C-fiber(GO:0044299)
4.2	21.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
4.2	25.3	GO:0000923	equatorial microtubule organizing center(GO:0000923)
4.1	53.6	GO:0001673	male germ cell nucleus(GO:0001673)
4.1	24.6	GO:0070531	BRCA1-A complex(GO:0070531)
4.1	8.1	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
4.1	20.3	GO:0002081	outer acrosomal membrane(GO:0002081)
4.1	28.4	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
4.0	44.5	GO:0031258	lamellipodium membrane(GO:0031258)
4.0	52.2	GO:0002199	zona pellucida receptor complex(GO:0002199)
4.0	12.0	GO:0005745	m-AAA complex(GO:0005745)
4.0	36.0	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
4.0	27.8	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
4.0	47.6	GO:0005876	spindle microtubule(GO:0005876)
3.9	39.4	GO:0031143	pseudopodium(GO:0031143)
3.9	11.6	GO:0097543	ciliary inversin compartment(GO:0097543)
3.9	19.3	GO:0005726	perichromatin fibrils(GO:0005726)
3.9	34.8	GO:0032009	early phagosome(GO:0032009)
3.8	18.9	GO:0043527	tRNA methyltransferase complex(GO:0043527)
3.7	11.2	GO:0032798	Swi5-Sfr1 complex(GO:0032798)
3.7	22.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
3.7	14.9	GO:0071797	LUBAC complex(GO:0071797)
3.7	11.2	GO:0097651	phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
3.7	14.8	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
3.7	22.2	GO:1990246	uniplex complex(GO:1990246)
3.7	44.3	GO:0042581	specific granule(GO:0042581)
3.7	187.7	GO:0000776	kinetochore(GO:0000776)
3.7	99.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
3.7	25.6	GO:0061700	GATOR2 complex(GO:0061700)
3.6	32.8	GO:0000813	ESCRT I complex(GO:0000813)
3.6	21.6	GO:0016602	CCAAT-binding factor complex(GO:0016602)
3.6	43.0	GO:0044666	MLL3/4 complex(GO:0044666)
3.5	3.5	GO:0031095	platelet dense tubular network membrane(GO:0031095)
3.5	1049.4	GO:0000790	nuclear chromatin(GO:0000790)
3.5	408.5	GO:0001650	fibrillar center(GO:0001650)
3.4	24.1	GO:0097504	Gemini of coiled bodies(GO:0097504)
3.4	10.2	GO:0000814	ESCRT II complex(GO:0000814)
3.4	44.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
3.4	17.0	GO:0071547	piP-body(GO:0071547)
3.4	40.3	GO:0097539	ciliary transition fiber(GO:0097539)
3.3	29.7	GO:0008278	cohesin complex(GO:0008278)
3.3	6.6	GO:0071011	precatalytic spliceosome(GO:0071011)
3.3	19.7	GO:0005879	axonemal microtubule(GO:0005879)
3.3	65.8	GO:0002102	podosome(GO:0002102)
3.2	22.6	GO:0000137	Golgi cis cisterna(GO:0000137)
3.2	6.4	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
3.2	102.3	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
3.2	3.2	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
3.2	12.7	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
3.2	38.0	GO:0030014	CCR4-NOT complex(GO:0030014)
3.2	31.5	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
3.1	18.6	GO:1990111	spermatoproteasome complex(GO:1990111)
3.1	49.4	GO:0032039	integrator complex(GO:0032039)
3.1	116.9	GO:0000786	nucleosome(GO:0000786)
3.0	90.4	GO:0034451	centriolar satellite(GO:0034451)
3.0	9.0	GO:0035838	growing cell tip(GO:0035838)
3.0	14.8	GO:0005672	transcription factor TFIIA complex(GO:0005672)
2.9	38.1	GO:0005849	mRNA cleavage factor complex(GO:0005849)
2.9	8.7	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
2.9	17.4	GO:0071203	WASH complex(GO:0071203)
2.9	46.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
2.9	26.0	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
2.9	71.9	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
2.8	111.0	GO:0000118	histone deacetylase complex(GO:0000118)
2.8	16.6	GO:0005638	lamin filament(GO:0005638)
2.8	11.1	GO:0005607	laminin-2 complex(GO:0005607)
2.8	52.5	GO:0005680	anaphase-promoting complex(GO:0005680)
2.8	8.3	GO:0097232	lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
2.7	164.8	GO:0000781	chromosome, telomeric region(GO:0000781)
2.7	13.7	GO:1990357	terminal web(GO:1990357)
2.7	5.5	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
2.7	16.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
2.7	37.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
2.7	13.3	GO:0090543	Flemming body(GO:0090543)
2.6	10.6	GO:0031417	NatC complex(GO:0031417)
2.6	45.0	GO:0030670	phagocytic vesicle membrane(GO:0030670)
2.6	23.7	GO:0016600	flotillin complex(GO:0016600)
2.6	124.4	GO:0017053	transcriptional repressor complex(GO:0017053)
2.6	28.4	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
2.6	658.4	GO:0016607	nuclear speck(GO:0016607)
2.4	4.8	GO:0033503	HULC complex(GO:0033503)
2.4	16.8	GO:0071986	Ragulator complex(GO:0071986)
2.4	35.7	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
2.4	287.3	GO:0001726	ruffle(GO:0001726)
2.3	46.9	GO:0015030	Cajal body(GO:0015030)
2.3	37.5	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
2.3	9.2	GO:0070436	Grb2-EGFR complex(GO:0070436)
2.3	6.9	GO:0000172	ribonuclease MRP complex(GO:0000172)
2.2	24.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
2.2	19.6	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
2.1	16.7	GO:0019013	viral nucleocapsid(GO:0019013)
2.1	16.6	GO:0032593	insulin-responsive compartment(GO:0032593)
2.1	193.1	GO:0005884	actin filament(GO:0005884)
2.1	4.1	GO:0008537	proteasome activator complex(GO:0008537)
2.1	4.1	GO:0099522	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
2.1	6.2	GO:0030485	smooth muscle contractile fiber(GO:0030485)
2.0	59.3	GO:0016235	aggresome(GO:0016235)
1.9	9.7	GO:1903767	sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
1.9	26.7	GO:0017119	Golgi transport complex(GO:0017119)
1.9	3.8	GO:1990630	IRE1-RACK1-PP2A complex(GO:1990630)
1.9	136.0	GO:0005814	centriole(GO:0005814)
1.9	507.8	GO:0005925	focal adhesion(GO:0005925)
1.9	9.3	GO:0031904	endosome lumen(GO:0031904)
1.8	90.2	GO:0016605	PML body(GO:0016605)
1.8	35.6	GO:0032588	trans-Golgi network membrane(GO:0032588)
1.7	43.5	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
1.7	301.1	GO:0005694	chromosome(GO:0005694)
1.7	8.6	GO:0033588	Elongator holoenzyme complex(GO:0033588)
1.7	5.2	GO:0097208	alveolar lamellar body(GO:0097208)
1.7	3.4	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
1.7	3.4	GO:1990429	Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
1.7	6.8	GO:0032021	NELF complex(GO:0032021)
1.7	18.5	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
1.7	6.7	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
1.7	3.3	GO:0061673	mitotic spindle astral microtubule(GO:0061673)
1.6	24.7	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
1.6	56.8	GO:0016592	mediator complex(GO:0016592)
1.6	6.4	GO:0097422	tubular endosome(GO:0097422)
1.6	6.4	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
1.6	3.2	GO:0071942	XPC complex(GO:0071942)
1.6	4.7	GO:0070826	paraferritin complex(GO:0070826)
1.5	4.5	GO:0072487	MSL complex(GO:0072487)
1.5	6.0	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
1.5	4.5	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
1.5	34.1	GO:0005681	spliceosomal complex(GO:0005681)
1.5	8.8	GO:0090544	BAF-type complex(GO:0090544)
1.5	4.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
1.4	7.0	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
1.4	5.6	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
1.4	4.2	GO:0043511	inhibin complex(GO:0043511)
1.4	7.0	GO:0005845	mRNA cap binding complex(GO:0005845)
1.4	5.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
1.4	12.6	GO:0005833	hemoglobin complex(GO:0005833)
1.4	24.6	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
1.4	9.5	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
1.3	10.7	GO:0000930	gamma-tubulin complex(GO:0000930)
1.3	14.7	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
1.3	6.7	GO:0035098	ESC/E(Z) complex(GO:0035098)
1.3	6.7	GO:0000439	core TFIIH complex(GO:0000439)
1.3	92.5	GO:0045095	keratin filament(GO:0045095)
1.3	22.8	GO:0000421	autophagosome membrane(GO:0000421)
1.3	15.1	GO:0030057	desmosome(GO:0030057)
1.3	16.3	GO:0031519	PcG protein complex(GO:0031519)
1.2	9.9	GO:0097542	ciliary tip(GO:0097542)
1.2	12.3	GO:0035145	exon-exon junction complex(GO:0035145)
1.2	22.6	GO:0032993	protein-DNA complex(GO:0032993)
1.2	18.6	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
1.2	11.5	GO:0031082	BLOC complex(GO:0031082)
1.1	137.5	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
1.1	15.9	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
1.1	205.9	GO:0005667	transcription factor complex(GO:0005667)
1.1	62.8	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
1.1	15.9	GO:0032153	cell division site(GO:0032153) cell division site part(GO:0032155)
1.1	15.9	GO:0000123	histone acetyltransferase complex(GO:0000123)
1.1	8.5	GO:0044754	autolysosome(GO:0044754)
1.0	51.1	GO:0000922	spindle pole(GO:0000922)
1.0	60.4	GO:0031594	neuromuscular junction(GO:0031594)
1.0	8.1	GO:0030686	90S preribosome(GO:0030686)
1.0	7.0	GO:0031932	TORC2 complex(GO:0031932)
1.0	69.4	GO:0030139	endocytic vesicle(GO:0030139)
1.0	51.0	GO:0030027	lamellipodium(GO:0030027)
1.0	13.5	GO:0035097	histone methyltransferase complex(GO:0035097)
1.0	10.6	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
1.0	22.0	GO:0005844	polysome(GO:0005844)
0.9	50.3	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.9	384.5	GO:0005730	nucleolus(GO:0005730)
0.9	0.9	GO:0070195	growth hormone receptor complex(GO:0070195)
0.9	3.5	GO:0020003	symbiont-containing vacuole(GO:0020003)
0.9	5.1	GO:0005610	laminin-5 complex(GO:0005610)
0.8	0.8	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.8	24.8	GO:0005643	nuclear pore(GO:0005643)
0.8	1.6	GO:0043073	germ cell nucleus(GO:0043073)
0.8	2.4	GO:0034657	GID complex(GO:0034657)
0.8	2.3	GO:0033165	interphotoreceptor matrix(GO:0033165)
0.7	9.0	GO:0031528	microvillus membrane(GO:0031528)
0.7	22.5	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.7	12.3	GO:0009925	basal plasma membrane(GO:0009925)
0.7	0.7	GO:0033290	eukaryotic 48S preinitiation complex(GO:0033290)
0.7	3.5	GO:1990635	proximal dendrite(GO:1990635)
0.7	0.7	GO:0032437	cuticular plate(GO:0032437)
0.7	3.3	GO:1990909	Wnt signalosome(GO:1990909)
0.6	15.5	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.6	3.9	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.6	45.4	GO:0072562	blood microparticle(GO:0072562)
0.6	3.0	GO:0000242	pericentriolar material(GO:0000242)
0.6	656.2	GO:0005654	nucleoplasm(GO:0005654)
0.6	12.7	GO:0034399	nuclear periphery(GO:0034399)
0.6	5.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.5	19.8	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.5	14.9	GO:0016328	lateral plasma membrane(GO:0016328)
0.4	3.4	GO:0005796	Golgi lumen(GO:0005796)
0.4	1.1	GO:0098833	presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.4	0.4	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.3	14.6	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.3	0.3	GO:0034719	SMN-Sm protein complex(GO:0034719)
0.3	6.0	GO:0001533	cornified envelope(GO:0001533)
0.3	0.8	GO:0048500	signal recognition particle(GO:0048500)
0.3	0.5	GO:1990923	PET complex(GO:1990923)
0.2	2.9	GO:0046930	pore complex(GO:0046930)
0.2	0.8	GO:0036156	inner dynein arm(GO:0036156)
0.2	1.6	GO:0005775	vacuolar lumen(GO:0005775)
0.2	1.1	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.6	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	107.3	GO:0005615	extracellular space(GO:0005615)
0.1	0.2	GO:0071817	MMXD complex(GO:0071817)
0.1	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.1	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.7	GO:0005913	cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
35.7	214.3	GO:0019976	interleukin-2 binding(GO:0019976)
27.4	246.7	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
26.8	268.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
25.7	154.2	GO:0034647	histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
25.5	127.3	GO:0043120	tumor necrosis factor binding(GO:0043120)
24.7	74.1	GO:0044715	8-oxo-dGDP phosphatase activity(GO:0044715)
24.6	73.7	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
24.6	122.8	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
24.3	97.3	GO:0035877	death effector domain binding(GO:0035877)
21.9	65.7	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
19.4	77.5	GO:0042610	CD8 receptor binding(GO:0042610)
19.0	56.9	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
18.8	56.5	GO:0008481	sphinganine kinase activity(GO:0008481)
18.6	37.2	GO:0035800	deubiquitinase activator activity(GO:0035800)
18.0	126.1	GO:0035375	zymogen binding(GO:0035375)
17.5	157.8	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
17.3	86.4	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
17.3	69.1	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
16.8	134.3	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
16.7	66.6	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
16.5	99.3	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
16.3	16.3	GO:0019003	GDP binding(GO:0019003)
16.3	48.8	GO:0001069	regulatory region RNA binding(GO:0001069)
15.4	76.8	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
15.3	61.3	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
15.2	60.8	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
15.1	105.7	GO:0005138	interleukin-6 receptor binding(GO:0005138)
15.0	44.9	GO:0034211	GTP-dependent protein kinase activity(GO:0034211)
14.0	70.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
14.0	56.0	GO:0045159	myosin II binding(GO:0045159)
14.0	41.9	GO:0004335	galactokinase activity(GO:0004335)
13.5	80.9	GO:0019767	IgE receptor activity(GO:0019767)
13.4	67.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
13.4	93.7	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
13.3	26.7	GO:0001042	RNA polymerase I core binding(GO:0001042)
13.3	133.5	GO:0019957	C-C chemokine binding(GO:0019957)
13.0	39.1	GO:0046980	peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
13.0	65.1	GO:0032564	dATP binding(GO:0032564)
13.0	52.0	GO:0035614	snRNA stem-loop binding(GO:0035614)
12.9	77.5	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
12.9	12.9	GO:0030881	beta-2-microglobulin binding(GO:0030881)
12.8	38.4	GO:0016882	cyclo-ligase activity(GO:0016882)
12.7	38.1	GO:0008384	IkappaB kinase activity(GO:0008384)
12.7	38.0	GO:0002114	interleukin-33 receptor activity(GO:0002114)
12.7	278.4	GO:0042288	MHC class I protein binding(GO:0042288)
12.6	37.7	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
12.5	50.2	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
12.5	62.4	GO:0004974	leukotriene receptor activity(GO:0004974)
12.4	37.3	GO:0042134	rRNA primary transcript binding(GO:0042134)
12.4	86.5	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
12.2	97.6	GO:0030274	LIM domain binding(GO:0030274)
12.0	36.0	GO:0001716	L-amino-acid oxidase activity(GO:0001716)
12.0	47.9	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
11.9	35.7	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
11.9	47.6	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
11.8	47.1	GO:0048408	epidermal growth factor binding(GO:0048408)
11.8	106.0	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
11.7	199.4	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
11.7	58.4	GO:0030348	syntaxin-3 binding(GO:0030348)
11.7	35.0	GO:0046966	thyroid hormone receptor binding(GO:0046966)
11.6	127.6	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
11.6	81.1	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
11.6	57.8	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
11.5	46.1	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
11.4	57.1	GO:0061676	importin-alpha family protein binding(GO:0061676)
11.4	22.7	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
11.2	44.8	GO:0004949	cannabinoid receptor activity(GO:0004949)
11.2	67.0	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
11.1	44.6	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
11.1	210.9	GO:0023026	MHC class II protein complex binding(GO:0023026)
11.1	33.3	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
11.1	11.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
11.0	209.0	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
11.0	43.9	GO:0010997	anaphase-promoting complex binding(GO:0010997)
10.9	293.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
10.7	42.7	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
10.7	96.0	GO:0030957	Tat protein binding(GO:0030957)
10.5	31.6	GO:0019961	interferon binding(GO:0019961)
10.5	83.9	GO:0042609	CD4 receptor binding(GO:0042609)
10.5	83.8	GO:0035033	histone deacetylase regulator activity(GO:0035033)
10.4	31.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
10.4	31.1	GO:0009041	uridylate kinase activity(GO:0009041)
10.3	61.8	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
10.2	91.9	GO:0043515	kinetochore binding(GO:0043515)
10.2	40.6	GO:0070644	vitamin D response element binding(GO:0070644)
10.1	30.4	GO:0002060	purine nucleobase binding(GO:0002060)
10.0	50.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
10.0	29.9	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
9.9	19.9	GO:0004000	adenosine deaminase activity(GO:0004000)
9.8	78.1	GO:0030621	U4 snRNA binding(GO:0030621)
9.7	29.1	GO:0070568	guanylyltransferase activity(GO:0070568)
9.7	145.4	GO:0019104	DNA N-glycosylase activity(GO:0019104)
9.7	164.5	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
9.6	57.4	GO:0051434	BH3 domain binding(GO:0051434)
9.5	332.2	GO:0042605	peptide antigen binding(GO:0042605)
9.5	37.8	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
9.4	47.2	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
9.3	55.9	GO:0070051	fibrinogen binding(GO:0070051)
9.2	109.9	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
9.1	146.2	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
9.1	18.1	GO:0031493	nucleosomal histone binding(GO:0031493)
8.9	26.6	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
8.9	26.6	GO:0051425	PTB domain binding(GO:0051425)
8.9	35.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
8.8	17.6	GO:0071936	coreceptor activity involved in Wnt signaling pathway(GO:0071936)
8.8	26.4	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
8.7	43.4	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
8.7	52.0	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
8.7	34.6	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
8.6	34.4	GO:0019776	Atg8 ligase activity(GO:0019776)
8.6	34.3	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
8.5	25.6	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
8.5	34.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
8.5	25.4	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
8.5	33.8	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
8.3	341.8	GO:0042169	SH2 domain binding(GO:0042169)
8.3	16.6	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
8.2	24.5	GO:0005427	proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
8.1	64.7	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
8.0	72.1	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
8.0	168.1	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
7.9	23.8	GO:0015292	uniporter activity(GO:0015292)
7.9	86.7	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
7.7	46.4	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
7.7	30.9	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
7.7	7.7	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
7.7	23.0	GO:0000403	Y-form DNA binding(GO:0000403)
7.6	151.5	GO:0070300	phosphatidic acid binding(GO:0070300)
7.5	60.0	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
7.5	127.4	GO:0070034	telomerase RNA binding(GO:0070034)
7.5	52.4	GO:0035184	histone threonine kinase activity(GO:0035184)
7.4	141.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
7.4	22.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
7.2	21.7	GO:0034437	sterol-transporting ATPase activity(GO:0034041) glycoprotein transporter activity(GO:0034437)
7.2	151.1	GO:0031996	thioesterase binding(GO:0031996)
7.1	28.4	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
7.1	35.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
7.1	91.9	GO:0003688	DNA replication origin binding(GO:0003688)
7.0	7.0	GO:0032138	DNA insertion or deletion binding(GO:0032135) single base insertion or deletion binding(GO:0032138)
7.0	21.0	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
7.0	34.9	GO:0050733	RS domain binding(GO:0050733)
7.0	76.8	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
7.0	118.2	GO:0043274	phospholipase binding(GO:0043274)
6.9	69.3	GO:0043023	ribosomal large subunit binding(GO:0043023)
6.9	27.7	GO:1901612	cardiolipin binding(GO:1901612)
6.9	20.7	GO:0052723	inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
6.9	41.3	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
6.8	40.8	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
6.8	40.8	GO:1990825	sequence-specific mRNA binding(GO:1990825)
6.8	338.2	GO:0031491	nucleosome binding(GO:0031491)
6.7	13.4	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
6.7	80.2	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
6.6	65.9	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
6.5	6.5	GO:0016778	diphosphotransferase activity(GO:0016778)
6.5	84.8	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
6.5	13.0	GO:0097100	supercoiled DNA binding(GO:0097100)
6.5	13.0	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
6.5	45.5	GO:0003924	GTPase activity(GO:0003924)
6.5	329.5	GO:0004527	exonuclease activity(GO:0004527)
6.4	19.2	GO:0070506	high-density lipoprotein particle receptor activity(GO:0070506)
6.3	38.0	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
6.3	50.7	GO:0070087	chromo shadow domain binding(GO:0070087)
6.2	25.0	GO:0035197	siRNA binding(GO:0035197)
6.2	37.4	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
6.2	18.6	GO:0038132	neuregulin binding(GO:0038132)
6.0	113.9	GO:0017056	structural constituent of nuclear pore(GO:0017056)
5.8	58.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
5.8	17.4	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
5.8	17.3	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
5.7	40.2	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
5.7	91.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
5.6	248.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
5.6	16.9	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
5.6	139.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
5.6	22.3	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
5.6	83.4	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
5.5	99.1	GO:0017160	Ral GTPase binding(GO:0017160)
5.4	358.0	GO:0004004	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
5.4	53.9	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
5.3	101.1	GO:0000993	RNA polymerase II core binding(GO:0000993)
5.3	237.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
5.3	163.3	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
5.3	21.0	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
5.2	21.0	GO:0036310	annealing helicase activity(GO:0036310)
5.2	36.7	GO:0048495	Roundabout binding(GO:0048495)
5.2	15.7	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
5.2	10.4	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
5.2	15.6	GO:0000150	recombinase activity(GO:0000150)
5.2	10.4	GO:0035613	RNA stem-loop binding(GO:0035613)
5.2	36.3	GO:0004957	prostaglandin E receptor activity(GO:0004957)
5.2	20.7	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
5.2	87.8	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
5.2	77.5	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
5.1	128.0	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
5.1	577.9	GO:0017124	SH3 domain binding(GO:0017124)
5.1	30.5	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
5.1	30.5	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
5.1	30.5	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
5.0	15.1	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
5.0	50.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
5.0	15.0	GO:1990955	telomerase inhibitor activity(GO:0010521) G-rich single-stranded DNA binding(GO:1990955)
5.0	24.9	GO:0034452	dynactin binding(GO:0034452)
5.0	64.4	GO:0019956	chemokine binding(GO:0019956)
4.9	800.8	GO:0042393	histone binding(GO:0042393)
4.9	98.8	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
4.9	29.6	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
4.9	19.6	GO:0001007	transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
4.9	43.9	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
4.9	43.9	GO:0042285	xylosyltransferase activity(GO:0042285)
4.8	9.7	GO:0055100	adiponectin binding(GO:0055100)
4.8	58.0	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
4.8	23.8	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
4.7	37.8	GO:0030368	interleukin-17 receptor activity(GO:0030368)
4.7	9.4	GO:0045295	gamma-catenin binding(GO:0045295)
4.7	14.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
4.7	121.5	GO:0017025	TBP-class protein binding(GO:0017025)
4.7	9.3	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
4.6	13.9	GO:0001605	adrenomedullin receptor activity(GO:0001605)
4.6	64.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
4.6	91.5	GO:0003678	DNA helicase activity(GO:0003678)
4.6	36.6	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
4.6	22.9	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
4.6	18.3	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
4.5	27.2	GO:0042162	telomeric DNA binding(GO:0042162)
4.5	18.1	GO:0004771	sterol esterase activity(GO:0004771)
4.5	4.5	GO:0032405	MutLalpha complex binding(GO:0032405)
4.5	94.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
4.5	80.6	GO:0035173	histone kinase activity(GO:0035173)
4.4	21.9	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
4.4	78.7	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
4.4	143.6	GO:0031369	translation initiation factor binding(GO:0031369)
4.3	8.7	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
4.3	13.0	GO:0016004	phospholipase activator activity(GO:0016004)
4.3	34.6	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
4.3	47.6	GO:0032036	myosin heavy chain binding(GO:0032036)
4.3	25.9	GO:0045545	syndecan binding(GO:0045545)
4.3	12.9	GO:0034584	piRNA binding(GO:0034584)
4.3	12.8	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
4.2	21.2	GO:0032767	copper-dependent protein binding(GO:0032767)
4.2	12.7	GO:0004832	valine-tRNA ligase activity(GO:0004832)
4.2	17.0	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
4.2	29.4	GO:0004064	arylesterase activity(GO:0004064)
4.2	29.3	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
4.2	8.4	GO:0004827	proline-tRNA ligase activity(GO:0004827)
4.2	12.5	GO:0031208	POZ domain binding(GO:0031208)
4.1	24.6	GO:0098821	BMP receptor activity(GO:0098821)
4.1	4.1	GO:0005290	L-histidine transmembrane transporter activity(GO:0005290)
4.0	198.2	GO:0019843	rRNA binding(GO:0019843)
4.0	16.0	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
4.0	8.0	GO:0004517	nitric-oxide synthase activity(GO:0004517)
4.0	15.8	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
4.0	19.8	GO:0070513	death domain binding(GO:0070513)
3.9	90.4	GO:0030515	snoRNA binding(GO:0030515)
3.9	7.8	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
3.8	11.5	GO:0004522	ribonuclease A activity(GO:0004522)
3.8	33.8	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
3.7	3.7	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
3.7	14.9	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
3.7	11.2	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
3.7	11.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
3.7	22.3	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
3.7	54.8	GO:0032794	GTPase activating protein binding(GO:0032794)
3.5	35.4	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
3.5	17.6	GO:0004849	uridine kinase activity(GO:0004849)
3.5	10.5	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
3.5	7.0	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
3.5	21.0	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
3.5	13.9	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
3.5	118.0	GO:0003684	damaged DNA binding(GO:0003684)
3.5	10.4	GO:0031720	haptoglobin binding(GO:0031720)
3.4	13.8	GO:0004526	ribonuclease P activity(GO:0004526)
3.4	6.9	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
3.4	10.3	GO:0070569	uridylyltransferase activity(GO:0070569)
3.4	10.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
3.4	75.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
3.4	13.6	GO:0019002	GMP binding(GO:0019002)
3.4	27.1	GO:0051525	NFAT protein binding(GO:0051525)
3.3	10.0	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
3.3	73.2	GO:0005521	lamin binding(GO:0005521)
3.3	13.3	GO:0034061	DNA polymerase activity(GO:0034061)
3.3	9.9	GO:0005143	interleukin-12 receptor binding(GO:0005143)
3.3	46.0	GO:0043522	leucine zipper domain binding(GO:0043522)
3.3	9.8	GO:0030228	lipoprotein particle receptor activity(GO:0030228)
3.3	19.7	GO:1990446	U1 snRNP binding(GO:1990446)
3.2	711.8	GO:0003735	structural constituent of ribosome(GO:0003735)
3.2	138.0	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
3.2	22.3	GO:0070182	DNA polymerase binding(GO:0070182)
3.2	9.5	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
3.1	12.6	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
3.1	74.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
3.1	18.6	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
3.1	15.5	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
3.1	46.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
3.1	24.6	GO:0005536	glucose binding(GO:0005536)
3.1	58.0	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
3.0	12.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
3.0	213.6	GO:0003777	microtubule motor activity(GO:0003777)
3.0	3.0	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
2.9	29.2	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
2.9	11.7	GO:0004687	myosin light chain kinase activity(GO:0004687)
2.9	26.1	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
2.9	60.8	GO:0050699	WW domain binding(GO:0050699)
2.9	11.5	GO:1990254	keratin filament binding(GO:1990254)
2.9	54.5	GO:0048020	CCR chemokine receptor binding(GO:0048020)
2.9	5.7	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
2.8	39.9	GO:0019239	deaminase activity(GO:0019239)
2.8	87.9	GO:0022829	wide pore channel activity(GO:0022829)
2.8	8.4	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
2.8	39.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
2.7	11.0	GO:0004594	pantothenate kinase activity(GO:0004594)
2.7	16.4	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
2.7	16.3	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
2.7	38.0	GO:0070063	RNA polymerase binding(GO:0070063)
2.7	8.1	GO:0019863	IgE binding(GO:0019863)
2.7	16.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
2.7	24.3	GO:0004697	protein kinase C activity(GO:0004697)
2.7	13.5	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
2.6	5.3	GO:0004775	succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
2.6	10.5	GO:0047619	acylcarnitine hydrolase activity(GO:0047619)
2.6	7.8	GO:0070053	thrombospondin receptor activity(GO:0070053)
2.6	7.7	GO:0042834	peptidoglycan binding(GO:0042834)
2.6	7.7	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
2.5	71.3	GO:0004540	ribonuclease activity(GO:0004540)
2.5	27.6	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
2.5	52.7	GO:0000030	mannosyltransferase activity(GO:0000030)
2.5	14.9	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
2.5	12.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
2.5	7.4	GO:0001847	opsonin receptor activity(GO:0001847)
2.5	12.3	GO:0031849	olfactory receptor binding(GO:0031849)
2.5	7.4	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
2.4	12.2	GO:0008318	protein prenyltransferase activity(GO:0008318)
2.4	9.7	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
2.4	4.8	GO:0031752	D5 dopamine receptor binding(GO:0031752)
2.4	7.2	GO:0030626	U12 snRNA binding(GO:0030626)
2.4	19.2	GO:0016936	galactoside binding(GO:0016936)
2.4	7.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
2.4	16.8	GO:0043024	ribosomal small subunit binding(GO:0043024)
2.4	2.4	GO:0015616	DNA translocase activity(GO:0015616)
2.4	26.1	GO:0008131	primary amine oxidase activity(GO:0008131)
2.4	37.7	GO:0001618	virus receptor activity(GO:0001618)
2.3	4.7	GO:0030984	kininogen binding(GO:0030984)
2.3	364.4	GO:0001047	core promoter binding(GO:0001047)
2.3	9.3	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
2.3	20.9	GO:0005000	vasopressin receptor activity(GO:0005000)
2.3	6.9	GO:0000171	ribonuclease MRP activity(GO:0000171)
2.3	16.1	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
2.3	101.1	GO:0017080	sodium channel regulator activity(GO:0017080)
2.3	6.9	GO:0032027	myosin light chain binding(GO:0032027)
2.3	13.7	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
2.3	9.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.3	20.5	GO:0035497	cAMP response element binding(GO:0035497)
2.3	2.3	GO:0051766	inositol trisphosphate kinase activity(GO:0051766)
2.2	2.2	GO:0032427	GBD domain binding(GO:0032427)
2.2	11.2	GO:0000400	four-way junction DNA binding(GO:0000400)
2.2	35.8	GO:0015279	store-operated calcium channel activity(GO:0015279)
2.2	20.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
2.2	4.5	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
2.2	17.7	GO:0008172	S-methyltransferase activity(GO:0008172)
2.2	13.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
2.2	88.0	GO:1990782	protein tyrosine kinase binding(GO:1990782)
2.2	2.2	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
2.2	15.2	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
2.2	32.4	GO:0005351	sugar:proton symporter activity(GO:0005351)
2.2	6.5	GO:0004645	phosphorylase activity(GO:0004645)
2.2	10.8	GO:0004104	cholinesterase activity(GO:0004104)
2.1	21.5	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
2.1	40.5	GO:0036002	pre-mRNA binding(GO:0036002)
2.1	2.1	GO:0019238	cyclohydrolase activity(GO:0019238)
2.1	48.1	GO:0003823	antigen binding(GO:0003823)
2.1	64.7	GO:0051059	NF-kappaB binding(GO:0051059)
2.0	10.2	GO:0030280	structural constituent of epidermis(GO:0030280)
2.0	8.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
2.0	6.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
2.0	74.8	GO:0005044	scavenger receptor activity(GO:0005044)
2.0	18.2	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
2.0	10.0	GO:0035325	Toll-like receptor binding(GO:0035325)
2.0	39.8	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
2.0	17.8	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
2.0	7.8	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
1.9	3.9	GO:0046977	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
1.9	31.0	GO:0005149	interleukin-1 receptor binding(GO:0005149)
1.9	7.7	GO:0035473	lipase binding(GO:0035473)
1.9	9.6	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.9	15.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.9	5.7	GO:0050497	methylthiotransferase activity(GO:0035596) transferase activity, transferring alkylthio groups(GO:0050497)
1.9	3.8	GO:0050785	advanced glycation end-product receptor activity(GO:0050785)
1.9	11.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
1.9	138.3	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
1.9	54.2	GO:0034062	RNA polymerase activity(GO:0034062)
1.9	11.2	GO:0008173	RNA methyltransferase activity(GO:0008173)
1.8	62.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
1.8	2077.2	GO:0003723	RNA binding(GO:0003723)
1.8	5.5	GO:0017089	glycolipid transporter activity(GO:0017089)
1.8	23.9	GO:0042974	retinoic acid receptor binding(GO:0042974)
1.8	12.8	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
1.8	7.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.8	10.7	GO:0004568	chitinase activity(GO:0004568)
1.8	44.6	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
1.8	73.0	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
1.8	1.8	GO:0050692	DBD domain binding(GO:0050692)
1.8	8.9	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
1.8	24.8	GO:0003993	acid phosphatase activity(GO:0003993)
1.8	5.3	GO:0032217	riboflavin transporter activity(GO:0032217)
1.8	3.5	GO:0070698	type I activin receptor binding(GO:0070698)
1.7	15.5	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
1.7	5.2	GO:0004051	arachidonate 5-lipoxygenase activity(GO:0004051)
1.7	37.7	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
1.7	22.2	GO:0003796	lysozyme activity(GO:0003796)
1.7	8.5	GO:0070401	NADP+ binding(GO:0070401)
1.7	207.3	GO:0005057	receptor signaling protein activity(GO:0005057)
1.7	37.3	GO:0001968	fibronectin binding(GO:0001968)
1.7	23.7	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.7	5.1	GO:0030911	TPR domain binding(GO:0030911)
1.7	11.6	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
1.6	16.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
1.6	6.5	GO:0004920	interleukin-10 receptor activity(GO:0004920)
1.6	16.0	GO:0015926	glucosidase activity(GO:0015926)
1.6	6.4	GO:0016972	thiol oxidase activity(GO:0016972)
1.6	425.9	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.6	6.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
1.6	4.7	GO:0015350	methotrexate transporter activity(GO:0015350)
1.6	6.3	GO:0070728	leucine binding(GO:0070728)
1.6	4.7	GO:0015639	cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) chromium ion transmembrane transporter activity(GO:0070835)
1.5	37.0	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
1.5	4.6	GO:0004655	porphobilinogen synthase activity(GO:0004655)
1.5	12.3	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
1.5	3.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.5	6.1	GO:0050897	cobalt ion binding(GO:0050897)
1.5	7.6	GO:0008420	CTD phosphatase activity(GO:0008420)
1.5	4.5	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
1.5	3.0	GO:0045322	unmethylated CpG binding(GO:0045322)
1.5	17.6	GO:0051879	Hsp90 protein binding(GO:0051879)
1.5	2.9	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
1.4	15.8	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
1.4	200.2	GO:0051015	actin filament binding(GO:0051015)
1.4	39.9	GO:0003697	single-stranded DNA binding(GO:0003697)
1.4	10.0	GO:0050431	transforming growth factor beta binding(GO:0050431)
1.4	49.6	GO:0004402	histone acetyltransferase activity(GO:0004402)
1.4	2.8	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.4	253.9	GO:0030414	peptidase inhibitor activity(GO:0030414)
1.4	6.8	GO:0046624	sphingolipid transporter activity(GO:0046624)
1.3	4.0	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
1.3	32.3	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.3	6.7	GO:0004586	ornithine decarboxylase activity(GO:0004586)
1.3	20.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
1.3	27.8	GO:0070840	dynein complex binding(GO:0070840)
1.3	4.0	GO:0016263	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
1.3	6.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
1.3	14.3	GO:0071889	14-3-3 protein binding(GO:0071889)
1.3	3.8	GO:1990226	histone methyltransferase binding(GO:1990226)
1.3	3.8	GO:0004046	aminoacylase activity(GO:0004046)
1.3	16.4	GO:0008536	Ran GTPase binding(GO:0008536)
1.3	2.5	GO:0004536	deoxyribonuclease activity(GO:0004536)
1.3	23.9	GO:0030544	Hsp70 protein binding(GO:0030544)
1.3	74.1	GO:0019210	kinase inhibitor activity(GO:0019210)
1.3	3.8	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
1.2	7.3	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
1.2	3.6	GO:0004769	steroid delta-isomerase activity(GO:0004769)
1.2	4.9	GO:0008265	Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
1.2	256.1	GO:0005096	GTPase activator activity(GO:0005096)
1.2	27.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.2	2.4	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
1.2	972.0	GO:0003677	DNA binding(GO:0003677)
1.2	20.2	GO:0042826	histone deacetylase binding(GO:0042826)
1.2	47.3	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
1.2	11.8	GO:0015386	potassium:proton antiporter activity(GO:0015386)
1.2	25.7	GO:0043022	ribosome binding(GO:0043022)
1.2	7.0	GO:0015189	L-lysine transmembrane transporter activity(GO:0015189)
1.2	3.5	GO:0042895	antibiotic transporter activity(GO:0042895)
1.1	9.1	GO:0052744	phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
1.1	4.4	GO:0004967	glucagon receptor activity(GO:0004967)
1.1	100.8	GO:0008201	heparin binding(GO:0008201)
1.1	9.8	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
1.1	2.2	GO:0004040	amidase activity(GO:0004040)
1.1	3.3	GO:0004359	glutaminase activity(GO:0004359)
1.1	4.3	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
1.1	2.1	GO:0042015	interleukin-20 binding(GO:0042015)
1.1	4.3	GO:0050544	arachidonic acid binding(GO:0050544)
1.1	4.2	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
1.1	5.3	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
1.1	6.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
1.1	4.2	GO:0034711	inhibin binding(GO:0034711)
1.1	12.6	GO:0005344	oxygen transporter activity(GO:0005344)
1.0	5.2	GO:0038024	cargo receptor activity(GO:0038024)
1.0	17.7	GO:0097602	cullin family protein binding(GO:0097602)
1.0	3.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
1.0	3.0	GO:0015197	peptide transporter activity(GO:0015197)
1.0	5.0	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
1.0	86.1	GO:0003712	transcription cofactor activity(GO:0003712)
1.0	4.0	GO:0016833	oxo-acid-lyase activity(GO:0016833)
1.0	38.7	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
1.0	1.0	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
1.0	32.9	GO:0004896	cytokine receptor activity(GO:0004896)
1.0	14.5	GO:0046875	ephrin receptor binding(GO:0046875)
1.0	13.5	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.0	14.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.9	5.6	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.9	4.6	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.9	4.6	GO:0004969	histamine receptor activity(GO:0004969)
0.9	27.8	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.9	5.3	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.9	2.6	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.9	2.6	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.9	7.8	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.9	4.3	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.9	24.8	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.9	10.3	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.9	1.7	GO:0055105	ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.8	2.5	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.8	228.2	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.8	158.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.8	2.5	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.8	7.3	GO:0001727	lipid kinase activity(GO:0001727)
0.8	4.7	GO:0035591	signaling adaptor activity(GO:0035591)
0.8	3.1	GO:0004452	isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.8	350.9	GO:0003676	nucleic acid binding(GO:0003676)
0.8	10.7	GO:0016918	retinal binding(GO:0016918)
0.8	5.3	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.8	29.6	GO:0015485	cholesterol binding(GO:0015485)
0.7	4.3	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.7	12.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.7	4.9	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.7	19.5	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.7	21.6	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.7	7.3	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.7	3.3	GO:0016726	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.6	6.4	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.6	6.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6	14.9	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.6	0.6	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.6	11.7	GO:0005212	structural constituent of eye lens(GO:0005212)
0.5	1.6	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.5	1.6	GO:0031770	growth hormone-releasing hormone receptor binding(GO:0031770)
0.5	1.6	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.5	2.6	GO:0008453	alanine-glyoxylate transaminase activity(GO:0008453)
0.5	2.1	GO:0050700	CARD domain binding(GO:0050700)
0.5	20.0	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.5	31.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.5	3.6	GO:0008430	selenium binding(GO:0008430)
0.5	4.0	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.5	2.5	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.5	8.4	GO:0002039	p53 binding(GO:0002039)
0.5	2.4	GO:0016803	ether hydrolase activity(GO:0016803)
0.5	1.4	GO:0016414	carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
0.5	39.5	GO:0019902	phosphatase binding(GO:0019902)
0.5	2.8	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5	1.4	GO:0032052	bile acid binding(GO:0032052)
0.5	3.3	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.5	51.4	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.5	0.9	GO:0015181	arginine transmembrane transporter activity(GO:0015181)
0.4	1.3	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.4	2.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.4	4.5	GO:0008198	ferrous iron binding(GO:0008198)
0.4	3.9	GO:0015232	heme transporter activity(GO:0015232)
0.4	10.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.4	2.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.4	27.8	GO:0008565	protein transporter activity(GO:0008565)
0.4	2.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.4	1.2	GO:0051870	methotrexate binding(GO:0051870)
0.4	1.2	GO:0019809	spermidine binding(GO:0019809)
0.4	9.7	GO:0019894	kinesin binding(GO:0019894)
0.4	5.6	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.4	2.8	GO:0017127	cholesterol transporter activity(GO:0017127)
0.3	1.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.3	70.3	GO:0030246	carbohydrate binding(GO:0030246)
0.3	13.9	GO:0008168	methyltransferase activity(GO:0008168)
0.3	2.3	GO:0004518	nuclease activity(GO:0004518)
0.3	92.2	GO:0005525	GTP binding(GO:0005525)
0.3	1.3	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.3	0.3	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.3	6.2	GO:0008013	beta-catenin binding(GO:0008013)
0.2	1.0	GO:0046527	glucosyltransferase activity(GO:0046527)
0.2	0.2	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.2	1.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.2	0.9	GO:0015057	thrombin receptor activity(GO:0015057)
0.2	2.1	GO:0015238	drug transmembrane transporter activity(GO:0015238)
0.2	0.8	GO:0031489	myosin V binding(GO:0031489)
0.2	1.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.2	0.4	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2	0.4	GO:0097108	hedgehog family protein binding(GO:0097108)
0.2	0.7	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.2	0.6	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.2	0.9	GO:0051400	BH domain binding(GO:0051400)
0.2	0.6	GO:0009881	photoreceptor activity(GO:0009881)
0.1	0.4	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	0.9	GO:0005148	prolactin receptor binding(GO:0005148)
0.1	3.3	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	0.8	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.9	GO:0043236	laminin binding(GO:0043236)
0.1	0.3	GO:0002046	opsin binding(GO:0002046)
0.1	0.5	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1	0.3	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.1	1.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.4	GO:0070412	R-SMAD binding(GO:0070412)
0.1	0.1	GO:0035004	1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0	0.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.2	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0015389	pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0	0.0	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.7	1099.8	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
14.5	304.7	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
12.1	349.9	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
11.5	103.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
11.4	537.3	PID BCR 5PATHWAY	BCR signaling pathway
10.8	184.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
10.6	507.8	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
10.5	136.8	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
9.6	106.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
9.5	66.5	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
9.1	262.6	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
9.0	162.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
8.8	201.6	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
8.5	389.1	PID AURORA B PATHWAY	Aurora B signaling
8.2	74.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
8.1	16.2	PID IL5 PATHWAY	IL5-mediated signaling events
7.9	86.6	PID IL2 1PATHWAY	IL2-mediated signaling events
7.7	269.5	PID FANCONI PATHWAY	Fanconi anemia pathway
7.5	351.9	PID PLK1 PATHWAY	PLK1 signaling events
7.4	221.8	PID BARD1 PATHWAY	BARD1 signaling events
7.3	145.9	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
7.1	164.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
6.8	34.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
6.7	86.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
6.6	132.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
6.6	118.3	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
6.4	244.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
6.4	12.8	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
6.2	93.2	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
6.2	290.9	PID RAC1 PATHWAY	RAC1 signaling pathway
6.1	42.5	PID EPO PATHWAY	EPO signaling pathway
6.0	90.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
6.0	36.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
5.5	205.2	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
5.5	143.8	PID FOXM1 PATHWAY	FOXM1 transcription factor network
5.5	16.6	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
5.4	97.4	PID IL23 PATHWAY	IL23-mediated signaling events
5.4	21.6	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
5.2	261.4	PID E2F PATHWAY	E2F transcription factor network
4.8	33.9	PID TRAIL PATHWAY	TRAIL signaling pathway
4.6	83.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
4.6	110.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
4.5	22.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
4.3	94.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
4.3	55.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
4.2	71.8	PID IL12 2PATHWAY	IL12-mediated signaling events
4.2	79.3	PID MYC PATHWAY	C-MYC pathway
4.2	87.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
4.1	40.7	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
4.0	125.1	PID RB 1PATHWAY	Regulation of retinoblastoma protein
4.0	127.0	PID TELOMERASE PATHWAY	Regulation of Telomerase
4.0	27.7	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
3.9	236.1	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
3.8	64.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
3.6	102.0	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
3.6	86.9	PID RHOA PATHWAY	RhoA signaling pathway
3.6	54.0	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
3.6	10.8	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
3.5	161.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
3.5	128.4	PID P53 REGULATION PATHWAY	p53 pathway
3.3	52.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
3.2	45.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
3.2	31.8	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
3.1	27.9	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
3.0	3.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
2.9	66.3	PID ALK1 PATHWAY	ALK1 signaling events
2.8	41.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
2.7	80.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
2.7	29.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
2.6	7.8	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
2.5	61.7	PID CONE PATHWAY	Visual signal transduction: Cones
2.4	14.4	PID CD40 PATHWAY	CD40/CD40L signaling
2.4	14.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
2.3	56.0	PID ILK PATHWAY	Integrin-linked kinase signaling
2.3	78.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
2.3	64.3	PID IL4 2PATHWAY	IL4-mediated signaling events
2.3	22.8	PID ATR PATHWAY	ATR signaling pathway
2.3	88.2	PID AR PATHWAY	Coregulation of Androgen receptor activity
2.2	196.2	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
2.2	4.4	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
2.1	14.9	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
2.1	24.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
2.0	9.9	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
1.9	7.7	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
1.9	26.8	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
1.9	9.4	PID IFNG PATHWAY	IFN-gamma pathway
1.9	40.8	PID TNF PATHWAY	TNF receptor signaling pathway
1.7	10.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
1.7	48.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
1.7	31.7	PID AR TF PATHWAY	Regulation of Androgen receptor activity
1.6	37.8	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
1.6	48.9	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
1.5	11.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
1.4	19.6	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.3	49.8	PID CMYB PATHWAY	C-MYB transcription factor network
1.2	16.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
1.2	17.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
1.2	3.6	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
1.2	35.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
1.2	2.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
1.1	10.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
1.1	5.7	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
1.1	12.3	PID ATF2 PATHWAY	ATF-2 transcription factor network
1.1	43.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
1.1	13.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
1.0	25.1	PID ENDOTHELIN PATHWAY	Endothelins
1.0	8.8	PID AURORA A PATHWAY	Aurora A signaling
1.0	9.8	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
1.0	40.1	PID NOTCH PATHWAY	Notch signaling pathway
0.9	14.2	PID RAS PATHWAY	Regulation of Ras family activation
0.9	176.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.9	4.6	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.9	6.5	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.8	2.4	PID ALK2 PATHWAY	ALK2 signaling events
0.7	6.5	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.7	0.7	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.6	15.9	PID MTOR 4PATHWAY	mTOR signaling pathway
0.6	4.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.5	21.9	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.5	4.0	ST ADRENERGIC	Adrenergic Pathway
0.5	3.3	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.4	6.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.3	2.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.3	5.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.3	3.5	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	0.8	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	1.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	1.6	PID P73PATHWAY	p73 transcription factor network
0.0	0.5	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.3	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.7	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
42.7	341.8	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
33.3	133.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
28.8	57.7	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
24.8	149.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
23.3	279.9	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
21.3	21.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
20.8	20.8	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
19.3	289.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
17.6	17.6	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
15.4	168.9	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
15.2	259.1	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
15.1	105.8	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
15.0	30.0	REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	Genes involved in E2F mediated regulation of DNA replication
14.0	266.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
13.9	152.8	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
13.6	611.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
12.4	694.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
12.4	384.0	REACTOME KINESINS	Genes involved in Kinesins
12.1	399.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
11.7	140.2	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
11.7	128.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
10.7	10.7	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
10.7	85.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
10.7	192.0	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
10.5	73.8	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
9.4	131.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
9.1	54.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
9.0	9.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
8.9	142.8	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
8.9	231.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
8.7	86.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
8.5	162.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
8.5	526.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
8.1	105.9	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
7.9	31.6	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
7.8	85.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
7.8	124.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
7.8	131.8	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
7.4	29.5	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
7.3	65.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
7.2	281.6	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
7.2	64.8	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
7.1	278.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
7.1	298.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
7.1	141.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
7.1	98.7	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
6.9	111.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
6.9	55.4	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
6.9	158.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
6.9	61.9	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
6.8	74.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
6.8	74.9	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
6.8	136.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
6.7	26.7	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
6.6	502.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
6.4	70.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
6.2	149.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
6.1	73.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
6.1	145.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
6.0	23.8	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
5.9	453.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
5.5	22.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
5.2	103.8	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
5.1	10.1	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
5.0	114.3	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
4.9	93.7	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
4.8	63.0	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
4.8	38.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
4.5	199.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
4.5	94.7	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
4.5	44.6	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
4.4	62.0	REACTOME G1 PHASE	Genes involved in G1 Phase
4.3	43.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
4.2	25.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
4.2	8.4	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
4.2	41.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
4.1	4.1	REACTOME HIV INFECTION	Genes involved in HIV Infection
4.0	40.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
3.9	161.8	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
3.9	15.7	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
3.9	62.6	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
3.9	23.4	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
3.8	37.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
3.8	33.8	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
3.7	48.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
3.7	40.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
3.6	40.1	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
3.6	65.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
3.4	43.9	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
3.4	23.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
3.3	120.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
3.3	107.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
3.2	70.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
3.2	436.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
3.2	12.6	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
3.2	44.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
3.1	6.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
3.1	198.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
3.0	21.0	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
3.0	3.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
3.0	11.9	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
2.9	128.7	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
2.9	23.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
2.8	51.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
2.7	8.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
2.6	78.9	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
2.6	28.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
2.5	37.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
2.4	41.0	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
2.4	40.8	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
2.4	33.2	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
2.3	30.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
2.3	9.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
2.2	75.6	REACTOME TRANSLATION	Genes involved in Translation
2.1	21.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
2.1	148.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
2.1	168.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
2.1	2.1	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
2.0	8.2	REACTOME DEFENSINS	Genes involved in Defensins
2.0	30.3	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
2.0	44.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
2.0	7.9	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
2.0	27.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
1.9	17.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
1.8	5.3	REACTOME CELL CYCLE CHECKPOINTS	Genes involved in Cell Cycle Checkpoints
1.7	77.2	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
1.6	16.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
1.6	17.6	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
1.6	22.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
1.6	46.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
1.5	3.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
1.5	24.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
1.4	15.8	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.4	23.8	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
1.4	20.5	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
1.4	34.0	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
1.3	6.7	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
1.3	9.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
1.3	2.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
1.2	12.1	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
1.2	11.6	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
1.1	26.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
1.1	21.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
1.0	15.7	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
1.0	8.1	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
1.0	53.4	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
1.0	18.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.0	30.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.8	4.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.8	3.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.7	22.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.7	2.9	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.7	15.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.7	7.1	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.7	3.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.7	5.6	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.7	4.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.7	5.4	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.7	11.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.6	7.6	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.6	24.7	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
0.6	5.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.6	9.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.5	10.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.5	1.5	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.5	9.4	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.4	1.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.4	13.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.4	12.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.4	6.8	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.4	15.2	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
0.4	4.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.4	1.8	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.4	0.7	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.3	8.0	REACTOME ACTIVATED TLR4 SIGNALLING	Genes involved in Activated TLR4 signalling
0.3	6.6	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.2	1.9	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.2	4.8	REACTOME INTERFERON SIGNALING	Genes involved in Interferon Signaling
0.2	2.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.2	3.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.2	3.1	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.2	3.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	3.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	1.7	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	0.2	REACTOME HIV LIFE CYCLE	Genes involved in HIV Life Cycle
0.0	0.5	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.5	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1

Results for Elf1_Elf2_Etv2_Elf4

Z-value: 4.14

Motif logo

Transcription factors associated with Elf1_Elf2_Etv2_Elf4

Activity-expression correlation:

Activity profile of Elf1_Elf2_Etv2_Elf4 motif

Sorted Z-values of Elf1_Elf2_Etv2_Elf4 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Elf1_Elf2_Etv2_Elf4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: