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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for E2f1

Z-value: 3.45

Motif logo

Transcription factors associated with E2f1

Gene Symbol Gene ID Gene Info
ENSRNOG00000016708 E2F transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f1rn6_v1_chr3_-_150073721_1500737210.731.1e-54Click!

Activity profile of E2f1 motif

Sorted Z-values of E2f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_43617247 205.40 ENSRNOT00000075065
histone cluster 1, H2ao
chr8_+_71514281 146.02 ENSRNOT00000022256
NS5A (hepatitis C virus) transactivated protein 9
chr7_+_53275676 136.63 ENSRNOT00000031986
E2F transcription factor 7
chr13_-_110257367 119.58 ENSRNOT00000005576
denticleless E3 ubiquitin protein ligase homolog
chr3_+_159421671 102.26 ENSRNOT00000010343
myeloblastosis oncogene-like 2
chr3_+_59153280 91.43 ENSRNOT00000002066
cell division cycle associated 7
chr9_-_26932201 90.77 ENSRNOT00000017081
minichromosome maintenance complex component 3
chr8_-_66893083 88.23 ENSRNOT00000037028
ENSRNOT00000091755
kinesin family member 23
chr9_-_10757720 84.48 ENSRNOT00000083848
ubiquitin-like with PHD and ring finger domains 1
chr8_-_33661049 77.42 ENSRNOT00000068037
Fli-1 proto-oncogene, ETS transcription factor
chr4_+_152995865 76.70 ENSRNOT00000014885
interleukin 17 receptor A
chr5_+_38844488 75.17 ENSRNOT00000009545
MMS22-like, DNA repair protein
chr18_+_51785111 74.02 ENSRNOT00000019351
lamin B1
chr9_-_10757954 73.34 ENSRNOT00000075265
ubiquitin-like with PHD and ring finger domains 1
chr7_-_3132457 72.74 ENSRNOT00000031963
cyclin dependent kinase 2
chr10_-_85947938 71.67 ENSRNOT00000037318
ENSRNOT00000082427
ADP-ribosylation factor like GTPase 5C
chr7_+_2643288 71.28 ENSRNOT00000047241
timeless circadian clock
chr1_-_94494980 70.55 ENSRNOT00000020014
cyclin E1
chr4_-_122741110 69.58 ENSRNOT00000008888
nucleoporin 210
chr10_-_106828884 67.43 ENSRNOT00000071420
thymidine kinase 1
chr1_+_75356220 66.84 ENSRNOT00000019799
DNA ligase 1
chr13_-_113927745 66.74 ENSRNOT00000010910
ENSRNOT00000080616
complement C3d receptor 2
chr6_+_43884678 66.68 ENSRNOT00000091551
ribonucleotide reductase regulatory subunit M2
chr4_-_77347011 65.86 ENSRNOT00000008149
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr20_-_3419831 65.51 ENSRNOT00000046798
mediator of DNA damage checkpoint 1
chr15_-_44411004 65.21 ENSRNOT00000031163
cell division cycle associated 2
chr5_+_144581427 63.30 ENSRNOT00000015227
claspin
chr5_+_154522119 62.61 ENSRNOT00000072618
E2F transcription factor 2
chr17_+_44520537 61.66 ENSRNOT00000077985
histone cluster 1, H2ai-like2
chr17_-_44815995 60.91 ENSRNOT00000091201
histone H4 variant H4-v.1
chr2_+_127686925 60.41 ENSRNOT00000086653
ENSRNOT00000016946
polo-like kinase 4
chr16_+_19800463 60.30 ENSRNOT00000023065
ankyrin repeat and LEM domain containing 1
chr17_-_43627629 60.24 ENSRNOT00000022965
histone cluster 1, H2af
chr5_+_62718787 59.60 ENSRNOT00000011112
polypeptide N-acetylgalactosaminyltransferase 12
chr6_+_91463308 59.50 ENSRNOT00000005595
leucine rich repeat protein 1
chr11_-_66695353 58.75 ENSRNOT00000063995
DNA polymerase theta
chr2_-_30780121 57.52 ENSRNOT00000025129
centromere protein H
chr9_+_81783349 56.14 ENSRNOT00000021548
CCR4-NOT transcription complex subunit 9
chr1_+_242959488 55.46 ENSRNOT00000015668
dedicator of cytokinesis 8
chr1_-_167347662 54.83 ENSRNOT00000027641
ENSRNOT00000076592
ras homolog family member G
chr6_+_144291974 54.69 ENSRNOT00000035255
non-SMC condensin II complex, subunit G2
chr5_+_59783890 54.21 ENSRNOT00000066277
maternal embryonic leucine zipper kinase
chr19_+_14523554 54.13 ENSRNOT00000084271
ENSRNOT00000064731
minichromosome maintenance complex component 5
chr3_-_110021149 53.59 ENSRNOT00000007808
fibrous sheath interacting protein 1
chr19_-_25220010 53.53 ENSRNOT00000008786
DDB1 and CUL4 associated factor 15
chr7_+_102586313 53.01 ENSRNOT00000006188
myelocytomatosis oncogene
chr1_+_167538263 51.64 ENSRNOT00000074058
ribonucleotide reductase catalytic subunit M1
chr1_+_82480195 51.08 ENSRNOT00000028051
transforming growth factor, beta 1
chr6_-_28663233 50.72 ENSRNOT00000070979
centromere protein O
chr13_+_98924962 49.82 ENSRNOT00000074148
lin-9 DREAM MuvB core complex component
chr5_-_163167299 49.53 ENSRNOT00000022478
TNF receptor superfamily member 1B
chr7_+_144078496 49.01 ENSRNOT00000055302
poly(rC) binding protein 2
chr10_+_108132105 48.35 ENSRNOT00000072534
chromobox 2
chr9_-_92963697 48.33 ENSRNOT00000023546
G protein-coupled receptor 55
chr20_-_3397039 48.10 ENSRNOT00000001084
ENSRNOT00000085259
protein phosphatase 1, regulatory subunit 18
chr17_-_44520240 47.55 ENSRNOT00000086538
histone cluster 1 H2B family member h
chr1_-_163129641 46.90 ENSRNOT00000083055
calpain 5
chr13_-_45068077 46.20 ENSRNOT00000004969
minichromosome maintenance complex component 6
chr17_+_72429618 45.98 ENSRNOT00000026187
GATA binding protein 3
chr2_-_198412350 45.78 ENSRNOT00000040210
histone H4-like
chr3_-_153250641 45.72 ENSRNOT00000008961
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr2_-_207300854 45.25 ENSRNOT00000018061
Mov10 RISC complex RNA helicase
chr7_+_27438351 45.25 ENSRNOT00000077976

chr20_-_6864571 44.69 ENSRNOT00000093253
peptidylprolyl isomerase like 1
chr7_-_140617721 44.58 ENSRNOT00000081355
tubulin, alpha 1B
chr17_+_44528125 44.08 ENSRNOT00000084538
similar to Histone H2A type 1
chr15_-_24056073 44.08 ENSRNOT00000015100
WD repeat and HMG-box DNA binding protein 1
chr9_+_112293388 43.80 ENSRNOT00000020767
mannosidase, alpha, class 2A, member 1
chr10_-_4910305 43.56 ENSRNOT00000033122
RecQ mediated genome instability 2
chr11_-_31847490 43.19 ENSRNOT00000061304
downstream neighbor of SON
chr1_+_144831523 42.67 ENSRNOT00000039748
mex-3 RNA binding family member B
chr5_+_153507093 42.59 ENSRNOT00000086650
ENSRNOT00000083645
runt-related transcription factor 3
chr11_+_89511191 42.57 ENSRNOT00000002510
minichromosome maintenance complex component 4
chr13_+_109713489 42.27 ENSRNOT00000004962
basic leucine zipper ATF-like transcription factor 3
chr5_-_129352886 42.22 ENSRNOT00000012088
cyclin-dependent kinase inhibitor 2C
chr1_+_257615088 41.42 ENSRNOT00000083183
lymphocyte-specific helicase-like
chr7_+_37812831 41.31 ENSRNOT00000005910
BTG anti-proliferation factor 1
chr7_-_31784192 41.13 ENSRNOT00000010869
apoptotic peptidase activating factor 1
chr7_-_119996824 41.08 ENSRNOT00000011079
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr14_-_3846891 41.04 ENSRNOT00000068520
cell division cycle 7
chr7_+_120125633 40.93 ENSRNOT00000012480
SH3-domain binding protein 1
chr4_-_170117325 40.83 ENSRNOT00000074198
histone H4-like
chr20_+_20576377 40.69 ENSRNOT00000000783
ENSRNOT00000086806
cyclin-dependent kinase 1
chr17_-_43770561 40.66 ENSRNOT00000088408
histone H4 variant H4-v.1
chr15_-_33193537 40.64 ENSRNOT00000016401
HAUS augmin-like complex, subunit 4
chrX_+_122507374 40.55 ENSRNOT00000032275
ENSRNOT00000080517
dedicator of cytokinesis 11
chr3_+_14299479 40.19 ENSRNOT00000092745
centriolin
chr8_+_48665652 40.11 ENSRNOT00000059715
H2A histone family, member X
chr7_-_12741296 40.04 ENSRNOT00000060648
Rho GTPase activating protein 45
chr5_+_152721940 39.97 ENSRNOT00000039322
aurora kinase A and ninein interacting protein
chr7_+_97984862 39.88 ENSRNOT00000008508
ATPase family, AAA domain containing 2
chr10_-_13619935 39.84 ENSRNOT00000064392
cyclin F
chr3_+_7422820 39.61 ENSRNOT00000064323
DEAD-box helicase 31
chr16_+_62483761 38.58 ENSRNOT00000058805
Werner syndrome RecQ like helicase
chr17_+_44522140 38.50 ENSRNOT00000080490
histone H4 variant H4-v.1
chr9_-_61528882 38.19 ENSRNOT00000015432
ankyrin repeat domain 44
chr19_-_914880 37.94 ENSRNOT00000017127
chemokine-like factor
chr15_-_59215803 37.70 ENSRNOT00000032301
laccase domain containing 1
chr16_+_48863418 37.55 ENSRNOT00000029868
primase and DNA directed polymerase
chr5_-_76756140 37.47 ENSRNOT00000022107
ENSRNOT00000089251
polypyrimidine tract binding protein 3
chr6_-_7421456 37.46 ENSRNOT00000006725
zinc finger protein 36, C3H type-like 2
chr1_+_199412834 37.37 ENSRNOT00000031891
fused in sarcoma RNA binding protein
chr10_-_19652898 37.29 ENSRNOT00000009648
spindle apparatus coiled-coil protein 1
chr10_-_108196217 37.23 ENSRNOT00000075440
chromobox 4
chr12_+_1460538 37.16 ENSRNOT00000001444
replication factor C subunit 3
chr4_+_161685258 37.13 ENSRNOT00000008012
ENSRNOT00000008003
forkhead box M1
chr20_-_6864387 37.10 ENSRNOT00000068527
peptidylprolyl isomerase like 1
chr16_-_19669153 36.93 ENSRNOT00000078714
ENSRNOT00000090775
HAUS augmin-like complex, subunit 8
chr8_-_39201588 36.91 ENSRNOT00000011226
STT3A, catalytic subunit of the oligosaccharyltransferase complex
chr6_-_11274932 36.75 ENSRNOT00000021538
mutS homolog 2
chr2_+_198359754 36.64 ENSRNOT00000048582
histone cluster 2 H2A family member b
chr3_-_13435979 36.58 ENSRNOT00000029600
PBX homeobox 3
chr5_-_152198813 36.52 ENSRNOT00000082953
high mobility group nucleosomal binding domain 2
chr1_-_154216340 36.15 ENSRNOT00000024082
embryonic ectoderm development
chr5_+_122647281 36.10 ENSRNOT00000066041
mesoderm induction early response 1, transcriptional regulator
chr10_-_56511583 35.73 ENSRNOT00000021402
similar to RIKEN cDNA 2810408A11
chr1_-_167347490 35.68 ENSRNOT00000076499
ras homolog family member G
chr5_+_68717519 35.52 ENSRNOT00000066226
structural maintenance of chromosomes 2
chr1_-_225952516 35.38 ENSRNOT00000043387
inner centromere protein
chr9_-_85445939 35.28 ENSRNOT00000072160
adaptor-related protein complex 1, sigma 3 subunit
chr20_+_3155652 35.06 ENSRNOT00000042882
RT1 class Ib, locus S2
chr12_-_21720094 35.05 ENSRNOT00000032838
zinc finger CW-type PWWP domain protein 1-like
chr20_-_3401273 34.96 ENSRNOT00000089257
ENSRNOT00000078451
ENSRNOT00000001085
nurim (nuclear envelope membrane protein)
chr12_+_24978483 34.88 ENSRNOT00000040069
elastin
chr10_-_70341837 34.74 ENSRNOT00000077261
schlafen family member 13
chr1_+_85386470 34.64 ENSRNOT00000093332
ENSRNOT00000044326
pleckstrin homology and RhoGEF domain containing G2
chr3_+_148579920 34.53 ENSRNOT00000012432
HCK proto-oncogene, Src family tyrosine kinase
chr7_-_12221330 34.45 ENSRNOT00000042204
polo-like kinase 5
chr10_+_11206226 34.05 ENSRNOT00000006979
transcription factor AP-4
chr7_+_54213319 34.04 ENSRNOT00000005286
nucleosome assembly protein 1-like 1
chr18_+_3162543 33.91 ENSRNOT00000078615
RB binding protein 8, endonuclease
chr12_-_47588335 33.89 ENSRNOT00000001595
ankyrin repeat domain 13a
chr17_-_75886523 33.49 ENSRNOT00000046266
USP6 N-terminal like
chr4_-_119742349 33.45 ENSRNOT00000013571
ISY1 splicing factor homolog
chr10_+_45289741 33.42 ENSRNOT00000066190
histone cluster 3, H2ba
chr5_+_24410863 33.36 ENSRNOT00000010591
tumor protein p53 inducible nuclear protein 1
chr10_+_17421075 33.31 ENSRNOT00000047011
serine/threonine kinase 10
chr1_-_142332588 33.26 ENSRNOT00000015065
Bloom syndrome RecQ like helicase
chr16_-_48921242 33.23 ENSRNOT00000041596
centromere protein U
chr8_-_78655856 33.17 ENSRNOT00000081185
transcription factor 12
chr19_+_37652969 33.02 ENSRNOT00000041970
capping protein regulator and myosin 1 linker 2
chr7_+_141882251 32.90 ENSRNOT00000087298
activating transcription factor 1
chr1_+_257614731 32.85 ENSRNOT00000075680
lymphocyte-specific helicase-like
chr1_+_257766691 32.82 ENSRNOT00000088148
helicase, lymphoid specific
chr17_-_36177457 32.75 ENSRNOT00000036978
membrane bound O-acyltransferase domain containing 1
chr1_-_136073483 32.73 ENSRNOT00000043854
ENSRNOT00000082564
ENSRNOT00000076340
solute carrier organic anion transporter family, member 3a1
chr7_-_12673659 32.49 ENSRNOT00000091650
ENSRNOT00000041277
ENSRNOT00000044865
polypyrimidine tract binding protein 1
chr16_+_60307148 32.27 ENSRNOT00000015239
exoribonuclease 1
chr1_-_32429917 32.27 ENSRNOT00000024111
lysophosphatidylcholine acyltransferase 1
chr12_-_46718355 32.06 ENSRNOT00000030031
RAB35, member RAS oncogene family
chr19_-_39087880 32.03 ENSRNOT00000070822
chromosome transmission fidelity factor 8
chr1_+_141120166 31.93 ENSRNOT00000050759
Fanconi anemia, complementation group I
chr17_-_44527801 31.69 ENSRNOT00000089643
histone cluster 1 H2B family member k
chr1_-_100554488 31.64 ENSRNOT00000026797
DNA polymerase delta 1, catalytic subunit
chr2_+_189430041 31.45 ENSRNOT00000023567
ENSRNOT00000023605
tropomyosin 3
chr5_-_77031120 31.44 ENSRNOT00000022987
INTS3 and NABP interacting protein
chr11_+_81358592 31.21 ENSRNOT00000002487
replication factor C subunit 4
chr20_+_3156170 31.17 ENSRNOT00000082880
RT1 class Ib, locus S2
chr1_+_13212324 31.16 ENSRNOT00000089607
RALBP1 associated Eps domain containing 1
chr3_-_119619865 31.14 ENSRNOT00000016172
inositol 1,4,5-trisphosphate receptor interacting protein-like 1
chr10_-_85049331 31.08 ENSRNOT00000012538
T-box 21
chr12_-_31323810 30.88 ENSRNOT00000001247
RAN, member RAS oncogene family
chr5_+_150032999 30.68 ENSRNOT00000013301
serine and arginine rich splicing factor 4
chr10_+_50928309 30.58 ENSRNOT00000033737
heparan sulfate-glucosamine 3-sulfotransferase 3A1
chr9_-_11027506 30.40 ENSRNOT00000071107
chromatin assembly factor 1 subunit A
chr7_-_28711761 30.18 ENSRNOT00000006249
PARP1 binding protein
chr12_-_19314016 30.17 ENSRNOT00000001825
minichromosome maintenance complex component 7
chr17_+_15814132 30.10 ENSRNOT00000032997
sushi domain containing 3
chr10_+_67427066 29.95 ENSRNOT00000035642
ATPase family, AAA domain containing 5
chrX_+_15098904 29.76 ENSRNOT00000007367
ENSRNOT00000087033
RNA binding motif (RNP1, RRM) protein 3
chr13_-_68858781 29.70 ENSRNOT00000065944
ENSRNOT00000092053
ring finger protein 2
chr19_+_25120128 29.65 ENSRNOT00000081243
sterile alpha motif domain containing 1
chr4_-_170145262 28.95 ENSRNOT00000074526
histone cluster 1, H4b
chr17_-_78812111 28.94 ENSRNOT00000021506
DNA cross-link repair 1C
chr19_+_49457677 28.72 ENSRNOT00000084445
centromere protein N
chr17_+_89742140 28.55 ENSRNOT00000077899
microtubule associated serine/threonine kinase-like
chr2_+_252018597 28.46 ENSRNOT00000020452
mucolipin 2
chr15_-_52443055 28.40 ENSRNOT00000087450
exportin 7
chr1_+_167539036 28.32 ENSRNOT00000093112
ribonucleotide reductase catalytic subunit M1
chr11_+_34101197 28.31 ENSRNOT00000002299
chromatin assembly factor 1 subunit B
chr12_-_24537313 28.31 ENSRNOT00000001975
bromodomain adjacent to zinc finger domain, 1B
chr18_-_27520295 28.11 ENSRNOT00000027544
GDNF family receptor alpha 3
chr4_-_119889949 27.97 ENSRNOT00000033687
H1 histone family, member X
chr4_-_159482869 27.78 ENSRNOT00000088333
RAD51 associated protein 1
chr1_-_85408413 27.74 ENSRNOT00000093558
ENSRNOT00000026576
ribosomal protein S16
chr6_-_92643847 27.72 ENSRNOT00000009183
glycogen phosphorylase L
chr17_+_17965881 27.49 ENSRNOT00000021751
DEK proto-oncogene
chr2_-_104133985 27.41 ENSRNOT00000088167
ENSRNOT00000067725
phosphodiesterase 7A
chr6_-_128149220 27.39 ENSRNOT00000014204
goosecoid homeobox
chr1_-_221251329 27.35 ENSRNOT00000031678
tigger transposable element derived 3
chr1_+_167538744 27.27 ENSRNOT00000093070
ribonucleotide reductase catalytic subunit M1
chr11_+_82373870 27.16 ENSRNOT00000002429
transformer 2 beta homolog (Drosophila)
chr3_+_72447969 27.14 ENSRNOT00000012022
structure specific recognition protein 1
chr1_-_84008293 27.03 ENSRNOT00000002053
small nuclear ribonucleoprotein polypeptide A
chr3_+_37599728 26.85 ENSRNOT00000090575
replication timing regulatory factor 1
chr6_-_128727374 26.66 ENSRNOT00000082152
spectrin repeat containing, nuclear envelope family member 3
chr6_+_126636491 26.54 ENSRNOT00000089601
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr1_+_142034423 26.44 ENSRNOT00000090006
tubulin tyrosine ligase-like family, member 13
chr16_+_19669411 26.41 ENSRNOT00000086105
ENSRNOT00000087576
ENSRNOT00000083651
ENSRNOT00000045099
myosin IXb
chr4_+_71740532 26.18 ENSRNOT00000023537
zyxin

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
29.4 88.2 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
27.6 220.8 GO:0010216 maintenance of DNA methylation(GO:0010216)
27.3 136.6 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
27.1 461.0 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
24.6 73.7 GO:0046601 positive regulation of centriole replication(GO:0046601)
24.5 122.7 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
24.2 72.7 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
23.8 71.3 GO:1904976 cellular response to bleomycin(GO:1904976)
23.4 117.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
22.4 67.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
22.0 87.8 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
17.7 53.0 GO:0072185 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586)
17.0 118.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
16.9 67.4 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
16.7 66.7 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
16.1 145.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
15.1 211.4 GO:0019985 translesion synthesis(GO:0019985)
14.7 58.7 GO:0097681 double-strand break repair via alternative nonhomologous end joining(GO:0097681)
14.0 84.3 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
13.4 40.1 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
13.1 209.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
12.5 37.6 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
12.5 312.4 GO:0006270 DNA replication initiation(GO:0006270)
12.0 60.0 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
11.6 34.9 GO:0071298 cellular response to L-ascorbic acid(GO:0071298)
11.6 34.7 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
11.5 46.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
11.4 45.7 GO:0046061 dATP catabolic process(GO:0046061)
11.3 78.9 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
11.2 56.1 GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
11.1 33.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
11.1 33.4 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
11.0 65.9 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
10.8 32.5 GO:0097694 establishment of RNA localization to telomere(GO:0097694) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
10.8 32.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
10.7 10.7 GO:0000019 regulation of mitotic recombination(GO:0000019)
10.0 39.8 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
9.5 66.5 GO:0090166 Golgi disassembly(GO:0090166)
9.4 46.9 GO:0060014 granulosa cell differentiation(GO:0060014)
9.4 65.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
9.4 37.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
9.4 28.1 GO:1905073 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
9.2 27.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
9.1 81.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
9.1 81.5 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
9.0 63.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
9.0 26.9 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
8.7 26.2 GO:0070637 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
8.5 85.4 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
8.5 42.7 GO:0072697 protein localization to cell cortex(GO:0072697)
8.4 25.3 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
8.4 25.1 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
8.4 16.7 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
8.3 33.0 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
8.2 131.2 GO:0051383 kinetochore organization(GO:0051383)
8.0 24.0 GO:2001226 negative regulation of inorganic anion transmembrane transport(GO:1903796) negative regulation of chloride transport(GO:2001226)
7.9 23.7 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
7.9 47.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
7.7 15.3 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
7.6 15.1 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
7.5 29.9 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
7.5 22.4 GO:1990108 protein linear deubiquitination(GO:1990108)
7.3 44.1 GO:0070827 chromatin maintenance(GO:0070827)
7.0 27.9 GO:0002184 cytoplasmic translational termination(GO:0002184)
6.9 20.8 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
6.9 27.4 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
6.7 20.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
6.7 20.1 GO:0046060 dATP metabolic process(GO:0046060)
6.7 33.4 GO:0042148 strand invasion(GO:0042148)
6.6 19.7 GO:0061181 regulation of chondrocyte development(GO:0061181)
6.6 45.9 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
6.5 26.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
6.5 19.4 GO:1902961 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
6.4 19.3 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
6.4 25.6 GO:2001206 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) TNFSF11-mediated signaling pathway(GO:0071847) positive regulation of osteoclast development(GO:2001206)
6.3 31.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
6.3 18.9 GO:0010986 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
6.3 18.8 GO:0060058 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
6.2 68.0 GO:0006013 mannose metabolic process(GO:0006013)
6.1 79.4 GO:0034508 centromere complex assembly(GO:0034508)
6.1 61.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
6.1 18.3 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
6.0 24.0 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
5.7 17.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111) positive regulation of histone H3-K9 trimethylation(GO:1900114)
5.7 33.9 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
5.6 16.8 GO:1902416 positive regulation of mRNA binding(GO:1902416)
5.6 11.2 GO:0099542 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
5.4 59.8 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
5.4 48.3 GO:0038171 cannabinoid signaling pathway(GO:0038171)
5.4 32.1 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
5.3 15.8 GO:1990009 retinal cell apoptotic process(GO:1990009)
5.3 36.9 GO:0043686 co-translational protein modification(GO:0043686)
5.2 47.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
5.2 20.8 GO:0009992 cellular water homeostasis(GO:0009992)
5.2 41.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
5.1 30.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
5.1 25.6 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
5.1 10.2 GO:1903936 cellular response to sodium arsenite(GO:1903936)
5.1 15.2 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
5.1 35.5 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
5.0 20.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
5.0 19.8 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
4.9 14.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
4.9 68.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
4.9 19.5 GO:1900623 regulation of mast cell cytokine production(GO:0032763) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
4.9 19.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
4.8 33.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
4.8 124.8 GO:0031297 replication fork processing(GO:0031297)
4.8 23.9 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
4.7 33.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
4.7 18.9 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
4.6 32.3 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
4.6 13.8 GO:2000409 positive regulation of T cell extravasation(GO:2000409) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
4.6 9.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
4.6 13.7 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
4.5 9.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
4.5 36.1 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085)
4.5 9.0 GO:0001834 trophectodermal cell proliferation(GO:0001834)
4.5 40.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
4.3 21.7 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
4.3 25.9 GO:0089700 protein kinase D signaling(GO:0089700)
4.3 12.9 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
4.3 29.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
4.2 50.9 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
4.2 12.6 GO:1903969 regulation of interleukin-6-mediated signaling pathway(GO:0070103) regulation of prolactin signaling pathway(GO:1902211) regulation of interleukin-4-mediated signaling pathway(GO:1902214) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
4.2 16.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
4.2 37.5 GO:0043249 erythrocyte maturation(GO:0043249)
4.1 12.4 GO:0014043 negative regulation of neuron maturation(GO:0014043)
4.1 282.5 GO:0006342 chromatin silencing(GO:0006342)
4.0 15.8 GO:0000076 DNA replication checkpoint(GO:0000076)
3.9 11.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
3.9 15.7 GO:0042891 antibiotic transport(GO:0042891)
3.9 11.6 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
3.8 15.3 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
3.8 19.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
3.7 22.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
3.7 14.9 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
3.7 29.6 GO:0006021 inositol biosynthetic process(GO:0006021)
3.7 29.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
3.6 10.8 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
3.6 17.9 GO:1901977 negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
3.5 21.0 GO:0061737 leukotriene signaling pathway(GO:0061737)
3.5 14.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
3.5 24.2 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
3.4 6.7 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
3.4 13.4 GO:1904401 cellular response to Thyroid stimulating hormone(GO:1904401)
3.3 26.7 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
3.3 55.5 GO:0001771 immunological synapse formation(GO:0001771)
3.2 9.7 GO:0060623 regulation of chromosome condensation(GO:0060623)
3.2 22.6 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
3.2 9.7 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
3.2 16.0 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
3.2 9.6 GO:1903699 tarsal gland development(GO:1903699)
3.2 15.9 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
3.2 12.7 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
3.1 15.7 GO:0033625 positive regulation of integrin activation(GO:0033625)
3.1 181.9 GO:0006334 nucleosome assembly(GO:0006334)
3.1 90.5 GO:1900027 regulation of ruffle assembly(GO:1900027)
3.1 49.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
3.1 30.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
3.0 57.0 GO:0035855 megakaryocyte development(GO:0035855)
3.0 23.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
3.0 17.7 GO:0018065 protein-cofactor linkage(GO:0018065)
3.0 11.8 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
2.9 11.7 GO:0051660 establishment of centrosome localization(GO:0051660)
2.9 20.3 GO:0006353 DNA-templated transcription, termination(GO:0006353)
2.9 8.6 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
2.8 42.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
2.8 22.7 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
2.8 11.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
2.8 11.2 GO:0031053 primary miRNA processing(GO:0031053)
2.8 13.8 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
2.7 16.1 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
2.7 24.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
2.7 21.4 GO:0010572 positive regulation of platelet activation(GO:0010572)
2.7 8.0 GO:2000342 positive regulation of hemoglobin biosynthetic process(GO:0046985) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
2.7 8.0 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054) corticotropin hormone secreting cell differentiation(GO:0060128)
2.6 26.4 GO:0018095 protein polyglutamylation(GO:0018095)
2.6 18.0 GO:0045048 protein insertion into ER membrane(GO:0045048)
2.5 14.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
2.5 12.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
2.4 26.4 GO:0035385 Roundabout signaling pathway(GO:0035385)
2.4 14.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
2.4 2.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.4 33.1 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
2.4 11.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
2.4 16.5 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
2.3 71.1 GO:0006284 base-excision repair(GO:0006284)
2.3 6.8 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
2.3 6.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
2.2 24.5 GO:0006405 RNA export from nucleus(GO:0006405)
2.2 74.8 GO:0006378 mRNA polyadenylation(GO:0006378)
2.2 193.2 GO:0051225 spindle assembly(GO:0051225)
2.2 36.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
2.1 51.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
2.1 8.5 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
2.1 42.2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
2.1 6.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
2.1 14.7 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
2.1 94.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
2.1 27.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
2.1 16.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
2.1 10.4 GO:0032202 telomere assembly(GO:0032202)
2.1 12.4 GO:0046477 galactosylceramide metabolic process(GO:0006681) glycosylceramide catabolic process(GO:0046477)
2.1 31.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
2.1 8.3 GO:0030043 actin filament fragmentation(GO:0030043)
2.1 10.3 GO:0048254 snoRNA localization(GO:0048254)
2.1 32.9 GO:0032025 response to cobalt ion(GO:0032025)
2.0 36.8 GO:0005513 detection of calcium ion(GO:0005513)
2.0 18.3 GO:0070673 response to interleukin-18(GO:0070673)
2.0 20.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
2.0 11.9 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
2.0 13.9 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
2.0 13.7 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
1.9 13.6 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
1.9 13.6 GO:0015871 choline transport(GO:0015871)
1.9 20.6 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
1.9 11.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
1.8 1.8 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
1.8 9.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.8 42.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
1.8 34.5 GO:0002347 response to tumor cell(GO:0002347)
1.8 7.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
1.8 32.4 GO:0015732 prostaglandin transport(GO:0015732)
1.8 21.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
1.7 12.0 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
1.7 67.7 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
1.7 49.0 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
1.7 5.0 GO:0000733 DNA strand renaturation(GO:0000733)
1.6 13.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
1.6 4.9 GO:0002071 glandular epithelial cell maturation(GO:0002071)
1.6 11.2 GO:0035878 nail development(GO:0035878)
1.6 14.3 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
1.5 10.8 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
1.5 10.7 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
1.5 9.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
1.5 7.6 GO:0072675 osteoclast fusion(GO:0072675)
1.5 4.6 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
1.5 27.4 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
1.5 4.5 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
1.5 4.4 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
1.5 13.1 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
1.5 5.8 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
1.4 33.3 GO:2000401 regulation of lymphocyte migration(GO:2000401)
1.4 13.0 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
1.4 2.9 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
1.4 2.8 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
1.4 11.1 GO:0070933 histone H4 deacetylation(GO:0070933)
1.4 5.5 GO:0042339 keratan sulfate metabolic process(GO:0042339)
1.4 9.7 GO:0015705 iodide transport(GO:0015705)
1.4 37.1 GO:0048246 macrophage chemotaxis(GO:0048246)
1.4 17.6 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
1.4 9.5 GO:0015670 carbon dioxide transport(GO:0015670)
1.3 10.6 GO:0080009 mRNA methylation(GO:0080009)
1.3 26.4 GO:0070266 necroptotic process(GO:0070266)
1.3 11.8 GO:0016576 histone dephosphorylation(GO:0016576)
1.3 51.0 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
1.3 2.5 GO:0009957 epidermal cell fate specification(GO:0009957)
1.3 3.8 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
1.3 48.8 GO:0016925 protein sumoylation(GO:0016925)
1.2 7.5 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
1.2 43.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
1.2 83.0 GO:0051028 mRNA transport(GO:0051028)
1.2 14.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
1.2 28.1 GO:0048485 sympathetic nervous system development(GO:0048485)
1.2 13.3 GO:0006298 mismatch repair(GO:0006298)
1.2 6.1 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
1.2 46.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
1.2 4.8 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
1.2 25.0 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
1.2 9.4 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
1.2 4.7 GO:0035565 regulation of pronephros size(GO:0035565)
1.2 3.5 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
1.2 7.0 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
1.2 4.6 GO:0070475 rRNA base methylation(GO:0070475)
1.1 3.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
1.1 8.0 GO:0006337 nucleosome disassembly(GO:0006337)
1.1 5.7 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
1.1 3.4 GO:0009751 response to salicylic acid(GO:0009751) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
1.1 6.8 GO:0070365 hepatocyte differentiation(GO:0070365)
1.1 4.5 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
1.1 12.3 GO:0032682 negative regulation of chemokine production(GO:0032682)
1.1 11.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
1.1 13.3 GO:0007062 sister chromatid cohesion(GO:0007062)
1.1 4.3 GO:0006011 UDP-glucose metabolic process(GO:0006011)
1.1 3.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.1 2.1 GO:0046599 regulation of centriole replication(GO:0046599)
1.1 4.2 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
1.1 10.6 GO:0070327 thyroid hormone transport(GO:0070327)
1.1 66.7 GO:0042100 B cell proliferation(GO:0042100)
1.0 7.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
1.0 2.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
1.0 12.4 GO:0006379 mRNA cleavage(GO:0006379)
1.0 20.7 GO:0060216 definitive hemopoiesis(GO:0060216)
1.0 14.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
1.0 15.3 GO:0019430 removal of superoxide radicals(GO:0019430)
1.0 21.4 GO:0045739 positive regulation of DNA repair(GO:0045739)
1.0 3.0 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
1.0 22.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
1.0 17.3 GO:0030903 notochord development(GO:0030903)
1.0 99.6 GO:0019882 antigen processing and presentation(GO:0019882)
1.0 46.9 GO:0007051 spindle organization(GO:0007051)
0.9 6.5 GO:0060056 mammary gland involution(GO:0060056)
0.9 7.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.9 13.5 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.9 7.2 GO:0001842 neural fold formation(GO:0001842)
0.9 7.0 GO:0033260 nuclear DNA replication(GO:0033260)
0.9 3.5 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.9 15.6 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.9 2.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.9 31.7 GO:0060976 coronary vasculature development(GO:0060976)
0.8 4.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.8 5.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.8 22.0 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.8 8.0 GO:0061157 mRNA destabilization(GO:0061157)
0.8 36.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.8 8.6 GO:0034982 mitochondrial protein processing(GO:0034982)
0.8 31.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.7 6.7 GO:0035608 protein deglutamylation(GO:0035608)
0.7 18.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.7 5.2 GO:0097240 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.7 136.2 GO:0006281 DNA repair(GO:0006281)
0.7 11.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.7 5.6 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.7 8.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.7 8.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.7 178.7 GO:0008380 RNA splicing(GO:0008380)
0.6 13.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.6 3.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.6 14.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.6 7.4 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.6 27.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.6 8.4 GO:0006491 N-glycan processing(GO:0006491)
0.6 2.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.6 7.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.6 5.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.6 17.1 GO:0046039 GTP metabolic process(GO:0046039)
0.5 13.2 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.5 20.5 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.5 2.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.5 1.0 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.5 7.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.5 2.3 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.5 12.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.5 11.3 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.5 3.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.4 3.9 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.4 11.7 GO:0009651 response to salt stress(GO:0009651)
0.4 3.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.4 7.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.4 4.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.4 5.8 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.4 1.2 GO:0048625 branchiomeric skeletal muscle development(GO:0014707) myoblast fate commitment(GO:0048625)
0.4 6.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.4 9.7 GO:0007567 parturition(GO:0007567)
0.4 9.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.4 2.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.4 3.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 14.9 GO:0001881 receptor recycling(GO:0001881)
0.4 14.1 GO:0030199 collagen fibril organization(GO:0030199)
0.4 5.2 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.4 17.7 GO:0045445 myoblast differentiation(GO:0045445)
0.4 14.4 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.3 1.4 GO:0036337 Fas signaling pathway(GO:0036337)
0.3 8.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.3 7.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.3 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.3 12.1 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.3 1.9 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.3 12.4 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.3 8.6 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.3 2.1 GO:0070459 prolactin secretion(GO:0070459)
0.3 15.7 GO:0042246 tissue regeneration(GO:0042246)
0.3 0.6 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.3 0.9 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.3 7.5 GO:0035987 endodermal cell differentiation(GO:0035987)
0.3 3.9 GO:0070166 enamel mineralization(GO:0070166)
0.3 2.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 14.9 GO:0042113 B cell activation(GO:0042113)
0.2 1.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 8.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 1.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 6.2 GO:0097352 autophagosome maturation(GO:0097352)
0.2 3.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.2 2.5 GO:0055070 copper ion homeostasis(GO:0055070)
0.2 1.7 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.2 3.7 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.2 0.4 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 1.8 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.2 5.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.2 2.1 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.1 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.1 2.8 GO:0001569 patterning of blood vessels(GO:0001569)
0.1 2.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.4 GO:0048333 mesodermal cell differentiation(GO:0048333)
0.1 7.2 GO:0048144 fibroblast proliferation(GO:0048144)
0.1 1.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 1.5 GO:0001675 acrosome assembly(GO:0001675)
0.1 7.6 GO:0071222 cellular response to lipopolysaccharide(GO:0071222)
0.1 0.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 14.4 GO:0042742 defense response to bacterium(GO:0042742)
0.1 1.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 15.9 GO:0045137 development of primary sexual characteristics(GO:0045137)
0.1 4.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 3.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0061377 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
43.5 173.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
32.9 361.7 GO:0042555 MCM complex(GO:0042555)
24.2 72.7 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
23.7 118.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
22.1 88.2 GO:0097149 centralspindlin complex(GO:0097149)
20.5 123.1 GO:0005663 DNA replication factor C complex(GO:0005663)
19.6 58.7 GO:0033186 CAF-1 complex(GO:0033186)
18.1 54.4 GO:0032301 MutSalpha complex(GO:0032301)
17.1 480.1 GO:0000788 nuclear nucleosome(GO:0000788)
13.6 40.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
12.1 48.3 GO:0070876 SOSS complex(GO:0070876)
12.1 60.4 GO:0098536 deuterosome(GO:0098536)
11.6 92.6 GO:0000796 condensin complex(GO:0000796)
11.2 78.2 GO:0001739 sex chromatin(GO:0001739)
11.0 66.0 GO:0001740 Barr body(GO:0001740)
11.0 32.9 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
10.2 51.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
9.4 85.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
8.9 88.9 GO:0070652 HAUS complex(GO:0070652)
8.6 68.8 GO:0005638 lamin filament(GO:0005638)
8.6 85.6 GO:0035102 PRC1 complex(GO:0035102)
8.2 41.1 GO:0043293 apoptosome(GO:0043293)
8.0 32.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
8.0 55.8 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
7.7 30.9 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
7.7 38.6 GO:0032389 MutLalpha complex(GO:0032389)
7.4 66.5 GO:0005688 U6 snRNP(GO:0005688)
7.0 28.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
7.0 34.9 GO:0071953 elastic fiber(GO:0071953)
7.0 27.9 GO:0018444 translation release factor complex(GO:0018444)
6.8 149.5 GO:0045120 pronucleus(GO:0045120)
6.7 33.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
6.6 32.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
6.5 274.8 GO:0000791 euchromatin(GO:0000791)
6.4 19.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
6.4 50.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
6.3 31.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
6.3 25.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
6.2 43.7 GO:0042382 paraspeckles(GO:0042382)
5.7 355.8 GO:0044815 DNA packaging complex(GO:0044815)
5.4 16.3 GO:0000811 GINS complex(GO:0000811)
5.1 35.5 GO:0031264 death-inducing signaling complex(GO:0031264)
5.0 19.8 GO:0071914 prominosome(GO:0071914)
4.8 14.4 GO:0044609 DBIRD complex(GO:0044609)
4.8 19.2 GO:0033553 rDNA heterochromatin(GO:0033553)
4.7 46.8 GO:0070187 telosome(GO:0070187)
4.6 18.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
4.5 13.6 GO:1990423 RZZ complex(GO:1990423)
4.5 31.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
4.5 22.4 GO:0071797 LUBAC complex(GO:0071797)
4.5 93.9 GO:0019013 viral nucleocapsid(GO:0019013)
4.4 21.9 GO:1990130 Iml1 complex(GO:1990130)
4.3 52.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
4.3 17.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
4.3 29.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
4.3 42.5 GO:0008290 F-actin capping protein complex(GO:0008290)
4.2 67.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
4.2 66.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
4.1 40.7 GO:0005662 DNA replication factor A complex(GO:0005662)
3.8 26.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
3.8 41.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
3.7 96.4 GO:0005721 pericentric heterochromatin(GO:0005721)
3.6 32.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
3.4 40.9 GO:0044327 dendritic spine head(GO:0044327)
3.4 47.5 GO:0001741 XY body(GO:0001741)
3.2 22.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
3.2 34.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
3.2 22.1 GO:0070761 pre-snoRNP complex(GO:0070761)
3.1 27.9 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
2.9 8.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
2.9 8.6 GO:0005745 m-AAA complex(GO:0005745)
2.8 19.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
2.8 11.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
2.7 26.6 GO:0005641 nuclear envelope lumen(GO:0005641)
2.6 15.8 GO:0030896 checkpoint clamp complex(GO:0030896)
2.5 29.8 GO:0097431 mitotic spindle pole(GO:0097431)
2.5 49.5 GO:0043196 varicosity(GO:0043196)
2.5 7.4 GO:0031010 ISWI-type complex(GO:0031010)
2.4 14.5 GO:0002142 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
2.4 9.6 GO:0032021 NELF complex(GO:0032021)
2.3 27.9 GO:0097539 ciliary transition fiber(GO:0097539)
2.3 78.9 GO:0005637 nuclear inner membrane(GO:0005637)
2.2 11.2 GO:0031094 platelet dense tubular network(GO:0031094)
2.2 13.3 GO:0090543 annulate lamellae(GO:0005642) Flemming body(GO:0090543)
2.2 93.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
2.1 8.4 GO:0072487 MSL complex(GO:0072487)
2.1 18.8 GO:0000138 Golgi trans cisterna(GO:0000138)
2.0 122.8 GO:0005643 nuclear pore(GO:0005643)
1.9 174.8 GO:0017053 transcriptional repressor complex(GO:0017053)
1.9 15.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.8 32.0 GO:0005849 mRNA cleavage factor complex(GO:0005849)
1.8 19.4 GO:0097418 neurofibrillary tangle(GO:0097418)
1.8 21.1 GO:0016342 catenin complex(GO:0016342)
1.7 12.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
1.7 8.6 GO:0035061 interchromatin granule(GO:0035061)
1.7 6.8 GO:0000125 PCAF complex(GO:0000125)
1.7 16.7 GO:0043020 NADPH oxidase complex(GO:0043020)
1.7 191.4 GO:0000775 chromosome, centromeric region(GO:0000775)
1.7 150.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
1.6 16.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.6 24.3 GO:0090533 cation-transporting ATPase complex(GO:0090533)
1.6 12.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.6 9.4 GO:0036396 MIS complex(GO:0036396)
1.5 1.5 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
1.4 22.2 GO:0042612 MHC class I protein complex(GO:0042612)
1.4 13.8 GO:0002177 manchette(GO:0002177)
1.4 6.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
1.3 24.3 GO:0032433 filopodium tip(GO:0032433)
1.3 13.4 GO:0042788 polysomal ribosome(GO:0042788)
1.3 430.3 GO:0005667 transcription factor complex(GO:0005667)
1.3 13.1 GO:0070531 BRCA1-A complex(GO:0070531)
1.3 12.7 GO:0090544 BAF-type complex(GO:0090544)
1.3 10.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.2 7.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
1.2 112.3 GO:0005814 centriole(GO:0005814)
1.1 10.3 GO:0000812 Swr1 complex(GO:0000812)
1.1 539.6 GO:0005694 chromosome(GO:0005694)
1.1 19.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.1 3.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.0 34.9 GO:0016235 aggresome(GO:0016235)
1.0 76.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
1.0 11.2 GO:0097526 spliceosomal tri-snRNP complex(GO:0097526)
1.0 15.7 GO:0031258 lamellipodium membrane(GO:0031258)
1.0 8.8 GO:0033263 CORVET complex(GO:0033263)
0.9 29.6 GO:0016592 mediator complex(GO:0016592)
0.8 16.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.8 6.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.8 8.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.8 28.8 GO:0016363 nuclear matrix(GO:0016363)
0.8 49.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.8 21.8 GO:0030904 retromer complex(GO:0030904)
0.7 30.0 GO:0045171 intercellular bridge(GO:0045171)
0.7 29.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.7 47.6 GO:0000922 spindle pole(GO:0000922)
0.7 2.1 GO:0072687 meiotic spindle(GO:0072687)
0.7 4.9 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.7 23.2 GO:0001772 immunological synapse(GO:0001772)
0.7 7.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.6 2.6 GO:0005588 collagen type V trimer(GO:0005588)
0.6 33.4 GO:0016605 PML body(GO:0016605)
0.6 47.2 GO:0032432 actin filament bundle(GO:0032432)
0.6 15.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.6 50.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.6 49.5 GO:0005902 microvillus(GO:0005902)
0.6 24.0 GO:0030286 dynein complex(GO:0030286)
0.6 2.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.5 12.3 GO:0032993 protein-DNA complex(GO:0032993)
0.5 12.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.5 21.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.5 9.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.5 21.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.5 25.6 GO:0005801 cis-Golgi network(GO:0005801)
0.5 1.4 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.5 173.6 GO:0016604 nuclear body(GO:0016604)
0.5 3.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.4 19.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.4 1.2 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.4 5.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.4 489.6 GO:0005654 nucleoplasm(GO:0005654)
0.3 8.9 GO:0008305 integrin complex(GO:0008305)
0.3 18.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.3 2.0 GO:0031519 PcG protein complex(GO:0031519)
0.3 1.9 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.3 7.1 GO:0005681 spliceosomal complex(GO:0005681)
0.3 3.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 5.5 GO:0000421 autophagosome membrane(GO:0000421)
0.3 0.8 GO:1903349 omegasome membrane(GO:1903349) omegasome(GO:1990462)
0.3 1.0 GO:0031417 NatC complex(GO:0031417)
0.3 2.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 3.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 7.6 GO:0002102 podosome(GO:0002102)
0.2 3.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 2.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 24.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 3.3 GO:0005614 interstitial matrix(GO:0005614)
0.2 3.3 GO:0002080 acrosomal membrane(GO:0002080)
0.2 2.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 9.7 GO:0036126 sperm flagellum(GO:0036126)
0.1 37.9 GO:0005925 focal adhesion(GO:0005925)
0.1 9.2 GO:0045095 keratin filament(GO:0045095)
0.1 10.3 GO:0072562 blood microparticle(GO:0072562)
0.1 6.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 32.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.9 GO:0070993 eukaryotic 43S preinitiation complex(GO:0016282) translation preinitiation complex(GO:0070993)
0.1 3.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.5 GO:0071547 piP-body(GO:0071547)
0.0 2.0 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
39.5 157.8 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
29.0 173.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
18.0 71.8 GO:0000403 Y-form DNA binding(GO:0000403)
17.3 51.9 GO:0032142 single guanine insertion binding(GO:0032142)
16.9 67.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
15.5 155.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
12.9 64.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
12.6 88.4 GO:0003896 DNA primase activity(GO:0003896)
12.4 37.1 GO:0002060 purine nucleobase binding(GO:0002060)
12.1 48.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
11.6 34.9 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
11.2 11.2 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
10.8 32.5 GO:0001069 regulatory region RNA binding(GO:0001069)
10.8 107.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
10.5 94.8 GO:0043515 kinetochore binding(GO:0043515)
10.2 51.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
9.8 49.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
9.8 58.7 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
9.6 76.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
9.2 46.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
9.1 63.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
9.0 36.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
9.0 17.9 GO:0019237 centromeric DNA binding(GO:0019237)
8.6 25.8 GO:0031493 nucleosomal histone binding(GO:0031493)
8.4 16.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
8.1 32.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
7.7 30.9 GO:0070883 pre-miRNA binding(GO:0070883)
7.6 68.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
7.5 75.0 GO:0070878 primary miRNA binding(GO:0070878)
7.4 29.7 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
7.2 35.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
6.8 27.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
6.7 33.4 GO:0000150 recombinase activity(GO:0000150)
6.6 290.0 GO:0003678 DNA helicase activity(GO:0003678)
6.5 26.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
6.5 64.9 GO:0032552 deoxyribonucleotide binding(GO:0032552)
6.4 89.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
6.3 25.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
6.3 18.8 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
6.1 18.3 GO:0070976 TIR domain binding(GO:0070976)
6.1 66.7 GO:0004875 complement receptor activity(GO:0004875)
5.9 17.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
5.6 16.7 GO:0032405 MutLalpha complex binding(GO:0032405)
5.5 158.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
5.5 21.9 GO:0000405 bubble DNA binding(GO:0000405)
5.4 43.2 GO:0070087 chromo shadow domain binding(GO:0070087)
5.2 15.7 GO:0042895 antibiotic transporter activity(GO:0042895)
4.9 97.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
4.8 33.9 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
4.8 19.1 GO:0070644 vitamin D response element binding(GO:0070644)
4.7 28.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
4.7 28.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
4.6 13.9 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
4.5 31.6 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
4.5 31.5 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
4.3 21.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
4.3 12.9 GO:1990715 mRNA CDS binding(GO:1990715)
4.3 845.7 GO:0042393 histone binding(GO:0042393)
4.2 29.6 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
4.2 21.0 GO:0004974 leukotriene receptor activity(GO:0004974)
4.2 12.6 GO:0097677 STAT family protein binding(GO:0097677)
4.1 82.9 GO:0032794 GTPase activating protein binding(GO:0032794)
4.1 24.5 GO:0032027 myosin light chain binding(GO:0032027)
4.1 4.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
4.0 44.5 GO:0070182 DNA polymerase binding(GO:0070182)
4.0 64.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
3.9 11.8 GO:0009041 uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
3.9 50.6 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
3.8 49.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
3.8 26.4 GO:0048495 Roundabout binding(GO:0048495)
3.7 100.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
3.7 22.2 GO:0046977 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
3.6 32.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
3.5 42.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
3.5 24.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
3.5 20.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
3.4 13.8 GO:0035877 death effector domain binding(GO:0035877)
3.4 10.3 GO:0016882 cyclo-ligase activity(GO:0016882)
3.3 43.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
3.3 16.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
3.2 18.9 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
3.1 58.8 GO:0070717 poly-purine tract binding(GO:0070717)
3.1 21.6 GO:0016018 cyclosporin A binding(GO:0016018)
3.1 30.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
2.9 8.8 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
2.9 17.6 GO:0032052 bile acid binding(GO:0032052)
2.9 11.6 GO:0019002 GMP binding(GO:0019002)
2.8 33.7 GO:0008046 axon guidance receptor activity(GO:0008046)
2.8 11.2 GO:0015057 thrombin receptor activity(GO:0015057)
2.7 98.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
2.7 27.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
2.7 16.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
2.7 10.7 GO:0001156 transcription factor activity, core RNA polymerase III binding(GO:0000995) transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007) TFIIIC-class transcription factor binding(GO:0001156)
2.6 7.8 GO:1990460 leptin receptor binding(GO:1990460)
2.6 15.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
2.6 113.4 GO:0070888 E-box binding(GO:0070888)
2.6 10.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
2.6 17.9 GO:0017070 U6 snRNA binding(GO:0017070) U4 snRNA binding(GO:0030621)
2.5 20.3 GO:0001055 RNA polymerase II activity(GO:0001055)
2.5 27.9 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
2.5 49.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
2.5 9.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
2.5 22.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
2.5 24.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
2.4 17.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
2.3 6.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
2.2 13.3 GO:0030983 mismatched DNA binding(GO:0030983)
2.2 45.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
2.1 21.4 GO:0070097 delta-catenin binding(GO:0070097)
2.1 19.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.1 54.6 GO:0036002 pre-mRNA binding(GO:0036002)
2.1 39.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
2.1 22.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
2.1 82.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
2.0 34.7 GO:0017160 Ral GTPase binding(GO:0017160)
2.0 38.6 GO:0070063 RNA polymerase binding(GO:0070063)
2.0 14.1 GO:0032184 SUMO polymer binding(GO:0032184)
2.0 25.9 GO:0004697 protein kinase C activity(GO:0004697)
2.0 17.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.9 19.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.9 22.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
1.9 16.9 GO:0003688 DNA replication origin binding(GO:0003688)
1.9 72.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
1.9 16.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
1.9 53.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
1.8 9.2 GO:0004586 ornithine decarboxylase activity(GO:0004586)
1.8 8.9 GO:0038132 neuregulin binding(GO:0038132)
1.7 14.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
1.7 11.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.7 10.2 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
1.7 102.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
1.7 34.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
1.7 113.9 GO:0003697 single-stranded DNA binding(GO:0003697)
1.6 4.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
1.6 32.7 GO:0043274 phospholipase binding(GO:0043274)
1.6 3.3 GO:0042809 vitamin D receptor binding(GO:0042809)
1.6 38.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.6 9.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
1.6 15.8 GO:0045294 alpha-catenin binding(GO:0045294)
1.5 27.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
1.5 4.5 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
1.5 11.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.5 16.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
1.4 57.8 GO:0042054 histone methyltransferase activity(GO:0042054)
1.4 4.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
1.4 37.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
1.4 37.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
1.4 71.1 GO:0031490 chromatin DNA binding(GO:0031490)
1.4 4.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
1.4 19.0 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.4 6.8 GO:0030957 Tat protein binding(GO:0030957)
1.3 30.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
1.3 10.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.3 10.4 GO:0070034 telomerase RNA binding(GO:0070034)
1.3 27.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
1.3 78.7 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
1.3 179.9 GO:0003714 transcription corepressor activity(GO:0003714)
1.3 2.5 GO:0005119 smoothened binding(GO:0005119)
1.2 6.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
1.2 12.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.2 8.5 GO:0008432 JUN kinase binding(GO:0008432)
1.2 21.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
1.2 9.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.2 9.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
1.2 39.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
1.2 10.4 GO:0070412 R-SMAD binding(GO:0070412)
1.1 3.3 GO:0033222 xylose binding(GO:0033222)
1.1 21.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.1 3.3 GO:0044388 small protein activating enzyme binding(GO:0044388)
1.0 37.9 GO:0008009 chemokine activity(GO:0008009)
1.0 22.1 GO:0008536 Ran GTPase binding(GO:0008536)
1.0 35.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
1.0 10.0 GO:0004017 adenylate kinase activity(GO:0004017)
1.0 14.8 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
1.0 14.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.0 24.9 GO:0070840 dynein complex binding(GO:0070840)
1.0 17.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
1.0 7.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.9 10.3 GO:1990405 protein antigen binding(GO:1990405)
0.9 5.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.9 73.4 GO:0003777 microtubule motor activity(GO:0003777)
0.9 7.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.9 31.1 GO:0042605 peptide antigen binding(GO:0042605)
0.8 4.2 GO:0070990 snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446)
0.8 9.2 GO:0005346 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.8 3.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.8 7.5 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.8 5.0 GO:0051434 BH3 domain binding(GO:0051434)
0.8 43.5 GO:0000049 tRNA binding(GO:0000049)
0.8 8.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.8 8.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.8 13.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.8 30.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.8 6.1 GO:0035497 cAMP response element binding(GO:0035497)
0.7 15.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.7 3.5 GO:0031996 thioesterase binding(GO:0031996)
0.7 5.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.7 24.9 GO:0002039 p53 binding(GO:0002039)
0.7 14.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.7 9.5 GO:0015250 water channel activity(GO:0015250)
0.7 30.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.7 185.8 GO:0003924 GTPase activity(GO:0003924)
0.7 15.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.6 9.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.6 13.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.6 40.2 GO:0005507 copper ion binding(GO:0005507)
0.6 4.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.6 11.6 GO:0005521 lamin binding(GO:0005521)
0.6 13.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.6 17.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.6 15.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.6 9.1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.6 7.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.5 713.2 GO:0003677 DNA binding(GO:0003677)
0.5 4.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.5 3.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 44.0 GO:0003682 chromatin binding(GO:0003682)
0.5 8.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.5 13.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5 17.2 GO:0042805 actinin binding(GO:0042805)
0.5 16.9 GO:0005109 frizzled binding(GO:0005109)
0.5 3.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.5 13.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.4 1.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.4 15.9 GO:0019894 kinesin binding(GO:0019894)
0.4 10.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.4 3.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 1.9 GO:0034235 GPI anchor binding(GO:0034235)
0.4 4.0 GO:0070403 NAD+ binding(GO:0070403)
0.4 6.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 13.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.3 3.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 11.4 GO:0008374 O-acyltransferase activity(GO:0008374)
0.3 3.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 13.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3 4.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.3 23.1 GO:0008565 protein transporter activity(GO:0008565)
0.3 7.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.3 7.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.3 2.7 GO:0005522 profilin binding(GO:0005522)
0.3 3.8 GO:0017091 AU-rich element binding(GO:0017091)
0.3 15.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 8.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.3 5.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.3 23.7 GO:0005125 cytokine activity(GO:0005125)
0.3 43.0 GO:0051015 actin filament binding(GO:0051015)
0.3 34.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 6.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 1.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.3 6.8 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.2 8.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 1.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 5.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 4.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 1.7 GO:0001671 ATPase activator activity(GO:0001671)
0.2 2.7 GO:0005243 gap junction channel activity(GO:0005243)
0.2 45.3 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.2 14.6 GO:0016209 antioxidant activity(GO:0016209)
0.2 4.0 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.2 0.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 12.4 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 0.9 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 7.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 42.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 1.9 GO:0005112 Notch binding(GO:0005112)
0.1 1.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 3.2 GO:0031072 heat shock protein binding(GO:0031072)
0.1 7.4 GO:0019902 phosphatase binding(GO:0019902)
0.1 3.1 GO:0043621 protein self-association(GO:0043621)
0.1 5.4 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 18.9 GO:0003723 RNA binding(GO:0003723)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
14.9 253.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
11.4 843.0 PID E2F PATHWAY E2F transcription factor network
7.5 309.4 PID ATR PATHWAY ATR signaling pathway
6.9 201.5 PID FANCONI PATHWAY Fanconi anemia pathway
5.6 100.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
4.1 24.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
3.8 99.0 PID ATM PATHWAY ATM pathway
3.7 11.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
3.5 159.1 PID AURORA B PATHWAY Aurora B signaling
3.4 34.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
3.3 9.9 PID FAS PATHWAY FAS (CD95) signaling pathway
3.1 49.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
3.0 77.1 PID IL27 PATHWAY IL27-mediated signaling events
2.7 21.2 PID S1P S1P4 PATHWAY S1P4 pathway
2.4 26.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
2.3 49.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
2.2 21.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
2.2 107.6 PID ILK PATHWAY Integrin-linked kinase signaling
2.0 15.9 ST JAK STAT PATHWAY Jak-STAT Pathway
1.9 37.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.9 67.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
1.8 52.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
1.8 44.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
1.7 14.0 PID ENDOTHELIN PATHWAY Endothelins
1.6 82.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
1.6 14.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
1.5 25.2 PID RAC1 PATHWAY RAC1 signaling pathway
1.5 156.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
1.5 68.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
1.4 31.3 PID ATF2 PATHWAY ATF-2 transcription factor network
1.4 102.0 PID CMYB PATHWAY C-MYB transcription factor network
1.4 17.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
1.3 61.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
1.1 13.8 PID TRAIL PATHWAY TRAIL signaling pathway
1.1 17.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
1.1 41.3 PID RHOA REG PATHWAY Regulation of RhoA activity
1.0 23.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.9 16.9 PID FOXO PATHWAY FoxO family signaling
0.9 30.6 PID LKB1 PATHWAY LKB1 signaling events
0.8 60.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.8 28.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.7 37.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.7 26.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.7 21.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.7 13.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.7 16.5 PID REELIN PATHWAY Reelin signaling pathway
0.7 24.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.7 10.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.7 10.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.6 25.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.6 15.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.6 21.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.6 6.8 PID MYC PATHWAY C-MYC pathway
0.5 21.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.5 2.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5 7.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.4 5.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.3 12.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.3 2.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 2.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 4.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 6.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.4 PID AURORA A PATHWAY Aurora A signaling
0.1 3.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
25.3 278.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
13.4 320.7 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
12.5 337.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
9.7 68.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
8.2 41.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
8.2 147.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
8.1 32.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
6.8 170.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
6.6 125.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
6.3 144.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
6.1 61.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
4.8 24.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
4.7 102.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
4.4 128.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
4.4 61.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
4.3 43.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
4.3 34.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
4.3 21.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
4.1 77.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
3.9 11.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
3.7 18.4 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
3.7 117.3 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
3.4 47.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
3.3 271.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
3.2 32.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
3.2 59.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
3.0 81.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
2.9 63.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
2.9 40.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
2.7 52.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
2.7 67.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
2.6 15.8 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
2.5 86.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
2.5 44.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
2.3 13.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
2.3 48.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
2.2 11.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
2.2 71.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
2.2 55.3 REACTOME G1 PHASE Genes involved in G1 Phase
2.1 12.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
2.1 21.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
2.0 32.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
2.0 25.5 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
1.9 33.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.8 45.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.8 21.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.7 32.9 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
1.7 52.2 REACTOME KINESINS Genes involved in Kinesins
1.7 11.6 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.6 16.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.6 16.0 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
1.6 11.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
1.6 45.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
1.5 21.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
1.4 15.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
1.4 25.8 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
1.4 16.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
1.4 62.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
1.3 12.1 REACTOME AMYLOIDS Genes involved in Amyloids
1.3 9.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.3 19.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.3 16.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
1.2 66.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
1.2 20.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
1.2 15.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.2 37.0 REACTOME MYOGENESIS Genes involved in Myogenesis
1.1 56.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
1.1 28.0 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
1.1 60.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.1 35.3 REACTOME DNA REPAIR Genes involved in DNA Repair
1.0 75.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
1.0 26.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
1.0 29.9 REACTOME SIGNAL AMPLIFICATION Genes involved in Signal amplification
1.0 26.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.9 18.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.9 20.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.9 15.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.8 9.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.8 9.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.7 10.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.6 10.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.6 5.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.6 4.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.6 21.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.6 18.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.5 8.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.5 16.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5 11.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.5 3.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.4 5.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.4 6.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.4 12.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.4 7.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.4 6.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.4 10.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 20.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 3.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.3 16.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 5.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 3.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 4.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 7.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 2.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 9.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 5.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.3 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 1.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 2.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.9 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane