ISMARA results: Dmc1

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Dmc1

Z-value: 1.60

Motif logo

Transcription factors associated with Dmc1

Gene Symbol	Gene ID	Gene Info
Dmc1 NCBI RGD Ensembl	ENSRNOG00000013807	DNA meiotic recombinase 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Dmc1	rn6_v1_chr7_-_120839577_120839577	-0.01	9.0e-01	Click!

Activity profile of Dmc1 motif

Sorted Z-values of Dmc1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_76722965 Show fit	83.54	ENSRNOT00000052129	LOC100912485 NCBI RGD Ensembl Show fit	alcohol sulfotransferase-like
chr14_+_22375955 Show fit	71.87	ENSRNOT00000063915 ENSRNOT00000034784	Ugt2b37 NCBI RGD Ensembl Show fit	UDP-glucuronosyltransferase 2 family, member 37
chr1_+_65576535 Show fit	64.34	ENSRNOT00000026575	Slc27a5 NCBI RGD Ensembl Show fit	solute carrier family 27 member 5
chr19_+_487723 Show fit	60.99	ENSRNOT00000061734	Ces2j NCBI RGD Ensembl Show fit	carboxylesterase 2J
chr1_-_258877045 Show fit	59.75	ENSRNOT00000071633	Cyp2c13 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 13
chr4_+_154391647 Show fit	57.97	ENSRNOT00000081488 ENSRNOT00000079192	Mug1 NCBI RGD Ensembl Show fit	murinoglobulin 1
chr17_+_8489266 Show fit	53.61	ENSRNOT00000016252	Lect2 NCBI RGD Ensembl Show fit	leukocyte cell-derived chemotaxin 2
chr14_+_22937421 Show fit	53.20	ENSRNOT00000065079	RGD1559459 NCBI RGD Ensembl Show fit	similar to Expressed sequence AI788959
chr1_-_258766881 Show fit	53.07	ENSRNOT00000015801	Cyp2c12 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 12
chr1_-_148119857 Show fit	52.00	ENSRNOT00000040325	LOC100361547 NCBI RGD Ensembl Show fit	Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr14_+_22806132 Show fit	51.46	ENSRNOT00000002728	Ugt2b10 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase 2 family, polypeptide B10
chr4_+_99063181 Show fit	51.16	ENSRNOT00000008840	Fabp1 NCBI RGD Ensembl Show fit	fatty acid binding protein 1
chr1_+_248723397 Show fit	47.34	ENSRNOT00000072188	LOC100911854 NCBI RGD Ensembl Show fit	mannose-binding protein C-like
chr16_+_18690246 Show fit	46.06	ENSRNOT00000081484	Mat1a NCBI RGD Ensembl Show fit	methionine adenosyltransferase 1A
chr7_-_15190796 Show fit	46.01	ENSRNOT00000006533	Cyp4f1 NCBI RGD Ensembl Show fit	cytochrome P450, family 4, subfamily f, polypeptide 1
chr14_+_22517774 Show fit	44.15	ENSRNOT00000047655	Ugt2b37 NCBI RGD Ensembl Show fit	UDP-glucuronosyltransferase 2 family, member 37
chr1_+_107344904 Show fit	43.06	ENSRNOT00000082582	Gas2 NCBI RGD Ensembl Show fit	growth arrest-specific 2
chr8_-_111761871 Show fit	43.03	ENSRNOT00000056483	RGD1310507 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 1300017J02
chr7_+_28066635 Show fit	42.11	ENSRNOT00000005844	Pah NCBI RGD Ensembl Show fit	phenylalanine hydroxylase
chr16_+_6970342 Show fit	42.06	ENSRNOT00000061294 ENSRNOT00000048344	Itih4 NCBI RGD Ensembl Show fit	inter-alpha-trypsin inhibitor heavy chain family, member 4
chr20_-_14193690 Show fit	41.11	ENSRNOT00000058237	Upb1 NCBI RGD Ensembl Show fit	beta-ureidopropionase 1
chr16_+_54164431 Show fit	40.94	ENSRNOT00000090763	Fgl1 NCBI RGD Ensembl Show fit	fibrinogen-like 1
chr1_+_83103925 Show fit	40.65	ENSRNOT00000047540 ENSRNOT00000028196	Cyp2b2 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily b, polypeptide 2
chr1_+_189359853 Show fit	40.02	ENSRNOT00000055083	Acsm1 NCBI RGD Ensembl Show fit	acyl-CoA synthetase medium-chain family member 1
chr5_-_19368431 Show fit	39.75	ENSRNOT00000012819	Cyp7a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 7, subfamily a, polypeptide 1
chr1_-_266428239 Show fit	38.75	ENSRNOT00000027160	Cyp17a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 17, subfamily a, polypeptide 1
chr9_+_16924520 Show fit	37.84	ENSRNOT00000025094	Slc22a7 NCBI RGD Ensembl Show fit	solute carrier family 22 member 7
chr6_+_127946686 Show fit	37.82	ENSRNOT00000082680	LOC500712 NCBI RGD Ensembl Show fit	Ab1-233
chr1_-_259287684 Show fit	37.00	ENSRNOT00000054724	Cyp2c22 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 22
chr2_-_23256158 Show fit	36.58	ENSRNOT00000015336	Bhmt NCBI RGD Ensembl Show fit	betaine-homocysteine S-methyltransferase
chr1_+_189289957 Show fit	35.30	ENSRNOT00000020587	Acsm1 NCBI RGD Ensembl Show fit	acyl-CoA synthetase medium-chain family member 1
chr1_+_83163079 Show fit	35.28	ENSRNOT00000077725 ENSRNOT00000034845	Cyp2b3 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily b, polypeptide 3
chr4_+_154215250 Show fit	34.01	ENSRNOT00000072465	Mug2 NCBI RGD Ensembl Show fit	murinoglobulin 2
chr17_+_78793336 Show fit	33.23	ENSRNOT00000057898	Mt1 NCBI RGD Ensembl Show fit	metallothionein 1
chr16_+_18690649 Show fit	32.51	ENSRNOT00000015190	Mat1a NCBI RGD Ensembl Show fit	methionine adenosyltransferase 1A
chr2_+_20857202 Show fit	32.13	ENSRNOT00000078919	Acot12 NCBI RGD Ensembl Show fit	acyl-CoA thioesterase 12
chr4_-_115332052 Show fit	30.53	ENSRNOT00000017643	Clec4f NCBI RGD Ensembl Show fit	C-type lectin domain family 4, member F
chr6_-_104631355 Show fit	30.36	ENSRNOT00000007825	Slc10a1 NCBI RGD Ensembl Show fit	solute carrier family 10 member 1
chr2_-_243407608 Show fit	29.88	ENSRNOT00000014631	Mttp NCBI RGD Ensembl Show fit	microsomal triglyceride transfer protein
chr2_+_235264219 Show fit	28.67	ENSRNOT00000086245	Cfi NCBI RGD Ensembl Show fit	complement factor I
chr12_-_22194287 Show fit	28.52	ENSRNOT00000082895 ENSRNOT00000001905	Tfr2 NCBI RGD Ensembl Show fit	transferrin receptor 2
chr1_+_83933942 Show fit	28.15	ENSRNOT00000068690	Cyp2f4 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily f, polypeptide 4
chr17_-_14949064 Show fit	28.11	ENSRNOT00000079489 ENSRNOT00000081454	AABR07027128.1 NCBI RGD Ensembl Show fit
chr16_-_81797815 Show fit	27.78	ENSRNOT00000026666	Proz NCBI RGD Ensembl Show fit	protein Z, vitamin K-dependent plasma glycoprotein
chr1_-_263803150 Show fit	26.56	ENSRNOT00000017840	Cyp2c23 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 23
chr9_-_4879755 Show fit	26.15	ENSRNOT00000047615	RGD1559960 NCBI RGD Ensembl Show fit	similar to Sulfotransferase K1 (rSULT1C2)
chr10_-_98544447 Show fit	26.03	ENSRNOT00000073149	Abca6 NCBI RGD Ensembl Show fit	ATP binding cassette subfamily A member 6
chr14_+_22251499 Show fit	25.58	ENSRNOT00000087991 ENSRNOT00000002705	Ugt2a1 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase 2 family, polypeptide A1
chr5_-_32956159 Show fit	25.56	ENSRNOT00000078264	Cnbd1 NCBI RGD Ensembl Show fit	cyclic nucleotide binding domain containing 1
chr3_-_148073554 Show fit	25.49	ENSRNOT00000055407	Defb27 NCBI RGD Ensembl Show fit	defensin beta 27
chr1_+_83653234 Show fit	25.10	ENSRNOT00000085008 ENSRNOT00000084230 ENSRNOT00000090071	Cyp2a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily a, polypeptide 1
chr17_-_69460321 Show fit	24.68	ENSRNOT00000058367	Akr1c1 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C1
chr2_+_182006242 Show fit	24.54	ENSRNOT00000064091	Fga NCBI RGD Ensembl Show fit	fibrinogen alpha chain
chr7_+_18310624 Show fit	23.73	ENSRNOT00000075258	Actl9 NCBI RGD Ensembl Show fit	actin-like 9
chr2_+_54466280 Show fit	23.72	ENSRNOT00000033112	C6 NCBI RGD Ensembl Show fit	complement C6
chrX_-_143558521 Show fit	23.41	ENSRNOT00000056598	LOC688842 NCBI RGD Ensembl Show fit	hypothetical protein LOC688842
chr12_+_19196611 Show fit	22.71	ENSRNOT00000001801	Azgp1 NCBI RGD Ensembl Show fit	alpha-2-glycoprotein 1, zinc-binding
chr8_+_52729003 Show fit	22.67	ENSRNOT00000081738	Nxpe4 NCBI RGD Ensembl Show fit	neurexophilin and PC-esterase domain family, member 4
chr5_+_151776004 Show fit	22.63	ENSRNOT00000009683	Nr0b2 NCBI RGD Ensembl Show fit	nuclear receptor subfamily 0, group B, member 2
chr2_+_150146234 Show fit	22.03	ENSRNOT00000018761	Aadac NCBI RGD Ensembl Show fit	arylacetamide deacetylase
chr9_+_100281339 Show fit	21.97	ENSRNOT00000029127	Agxt NCBI RGD Ensembl Show fit	alanine-glyoxylate aminotransferase
chr5_+_124476168 Show fit	21.79	ENSRNOT00000077754	RGD1564074 NCBI RGD Ensembl Show fit	similar to novel protein
chr1_-_241460868 Show fit	21.47	ENSRNOT00000054776	RGD1560242 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 1700028P14
chrX_-_65400298 Show fit	21.02	ENSRNOT00000032121	Vsig4 NCBI RGD Ensembl Show fit	V-set and immunoglobulin domain containing 4
chr1_-_89539210 Show fit	20.97	ENSRNOT00000077462 ENSRNOT00000028644	Hpn NCBI RGD Ensembl Show fit	hepsin
chr12_+_24158766 Show fit	20.80	ENSRNOT00000001963	Ccl26 NCBI RGD Ensembl Show fit	C-C motif chemokine ligand 26
chr2_+_114423533 Show fit	20.76	ENSRNOT00000091221	Slc2a2 NCBI RGD Ensembl Show fit	solute carrier family 2 member 2
chr14_+_22142364 Show fit	20.64	ENSRNOT00000002699	Sult1b1 NCBI RGD Ensembl Show fit	sulfotransferase family 1B member 1
chrX_-_79066932 Show fit	20.60	ENSRNOT00000057460	RGD1561552 NCBI RGD Ensembl Show fit	similar to WASP family 1
chr16_+_50181316 Show fit	20.49	ENSRNOT00000077662	F11 NCBI RGD Ensembl Show fit	coagulation factor XI
chrX_-_23139694 Show fit	20.37	ENSRNOT00000033656	Pfkfb1 NCBI RGD Ensembl Show fit	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr9_+_95274707 Show fit	20.28	ENSRNOT00000045163	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chr7_+_51794173 Show fit	20.26	ENSRNOT00000043774	Otogl NCBI RGD Ensembl Show fit	otogelin-like
chr17_-_43675934 Show fit	20.16	ENSRNOT00000081345	Hist1h1t NCBI RGD Ensembl Show fit	histone cluster 1 H1 family member t
chr9_-_113246545 Show fit	20.06	ENSRNOT00000034759	Tmem232 NCBI RGD Ensembl Show fit	transmembrane protein 232
chr1_-_164142206 Show fit	19.97	ENSRNOT00000081669	Dgat2 NCBI RGD Ensembl Show fit	diacylglycerol O-acyltransferase 2
chr7_-_20118466 Show fit	19.84	ENSRNOT00000080523	RGD1565071 NCBI RGD Ensembl Show fit	similar to hypothetical protein 4930509O22
chrX_-_153457040 Show fit	19.81	ENSRNOT00000084905	LOC689600 NCBI RGD Ensembl Show fit	hypothetical protein LOC689600
chr7_+_143629455 Show fit	19.77	ENSRNOT00000073951	Krt18 NCBI RGD Ensembl Show fit	keratin 18
chr1_+_229519506 Show fit	19.73	ENSRNOT00000016593	Glyatl2 NCBI RGD Ensembl Show fit	glycine-N-acyltransferase-like 2
chrX_-_14783792 Show fit	19.64	ENSRNOT00000087609	LOC691895 NCBI RGD Ensembl Show fit	similar to ferritin, heavy polypeptide-like 17
chr1_-_162385575 Show fit	19.46	ENSRNOT00000016540	Thrsp NCBI RGD Ensembl Show fit	thyroid hormone responsive
chrX_+_22674759 Show fit	19.44	ENSRNOT00000004683	LOC685789 NCBI RGD Ensembl Show fit	hypothetical protein LOC685789
chr3_+_143129248 Show fit	19.23	ENSRNOT00000006667	Cst8 NCBI RGD Ensembl Show fit	cystatin 8
chr16_-_49003246 Show fit	18.98	ENSRNOT00000089501	Acsl1 NCBI RGD Ensembl Show fit	acyl-CoA synthetase long-chain family member 1
chr11_-_69355854 Show fit	18.92	ENSRNOT00000002975	Ropn1 NCBI RGD Ensembl Show fit	rhophilin associated tail protein 1
chr9_+_95256627 Show fit	18.84	ENSRNOT00000025291	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chr15_+_36609296 Show fit	18.78	ENSRNOT00000010795	Rnf17 NCBI RGD Ensembl Show fit	ring finger protein 17
chr16_-_54628458 Show fit	18.59	ENSRNOT00000042587	Adam24 NCBI RGD Ensembl Show fit	ADAM metallopeptidase domain 24
chr2_+_104290726 Show fit	18.36	ENSRNOT00000017387	Dnajc5b NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member C5 beta
chr1_-_84834039 Show fit	18.30	ENSRNOT00000088960	AABR07002782.1 NCBI RGD Ensembl Show fit
chr1_-_167588630 Show fit	18.25	ENSRNOT00000050707	Olr39 NCBI RGD Ensembl Show fit	olfactory receptor 39
chr1_-_89543967 Show fit	18.12	ENSRNOT00000079631	Hpn NCBI RGD Ensembl Show fit	hepsin
chr5_-_39611053 Show fit	17.95	ENSRNOT00000046595	Fhl5 NCBI RGD Ensembl Show fit	four and a half LIM domains 5
chrX_+_110233170 Show fit	17.89	ENSRNOT00000036019	4930513O06Rik NCBI RGD Ensembl Show fit	RIKEN cDNA 4930513O06 gene
chr6_-_10891146 Show fit	17.85	ENSRNOT00000020328	Mcfd2 NCBI RGD Ensembl Show fit	multiple coagulation factor deficiency 2
chr2_-_188413219 Show fit	17.78	ENSRNOT00000065065	Fdps NCBI RGD Ensembl Show fit	farnesyl diphosphate synthase
chr9_+_95295701 Show fit	17.74	ENSRNOT00000025045	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chr1_+_102900286 Show fit	17.66	ENSRNOT00000017468	Ldha NCBI RGD Ensembl Show fit	lactate dehydrogenase A
chr17_+_76008807 Show fit	17.60	ENSRNOT00000070895	Echdc3 NCBI RGD Ensembl Show fit	enoyl CoA hydratase domain containing 3
chr1_-_81534140 Show fit	17.53	ENSRNOT00000027202	Tex101 NCBI RGD Ensembl Show fit	testis expressed 101
chr17_+_81352700 Show fit	17.51	ENSRNOT00000024736	Mrc1 NCBI RGD Ensembl Show fit	mannose receptor, C type 1
chr15_-_45550285 Show fit	17.38	ENSRNOT00000012948	Gucy1b2 NCBI RGD Ensembl Show fit	guanylate cyclase 1 soluble subunit beta 2
chr3_-_7141522 Show fit	17.37	ENSRNOT00000014572	Cel NCBI RGD Ensembl Show fit	carboxyl ester lipase
chr1_-_198486157 Show fit	17.33	ENSRNOT00000022758	Zg16 NCBI RGD Ensembl Show fit	zymogen granule protein 16
chr9_-_32868371 Show fit	17.29	ENSRNOT00000038369	LOC689725 NCBI RGD Ensembl Show fit	similar to chromosome 9 open reading frame 79
chr10_+_109950988 Show fit	17.16	ENSRNOT00000071293	LOC688321 NCBI RGD Ensembl Show fit	similar to Lung carbonyl reductase [NADPH] (NADPH-dependent carbonyl reductase) (LCR) (Adipocyte P27 protein) (AP27)
chr14_+_84274550 Show fit	17.15	ENSRNOT00000006053 ENSRNOT00000087383	Sec14l4 NCBI RGD Ensembl Show fit	SEC14-like lipid binding 4
chr5_-_75116490 Show fit	17.10	ENSRNOT00000042788	Txndc8 NCBI RGD Ensembl Show fit	thioredoxin domain containing 8
chr2_-_210749991 Show fit	16.98	ENSRNOT00000051261 ENSRNOT00000052403	Gstm6l NCBI RGD Ensembl Show fit	glutathione S-transferase, mu 6-like
chr15_-_57651041 Show fit	16.79	ENSRNOT00000072138	Spert NCBI RGD Ensembl Show fit	spermatid associated
chr15_+_80040842 Show fit	16.79	ENSRNOT00000043065	RGD1306441 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 4921530L21
chr16_-_24951612 Show fit	16.65	ENSRNOT00000018987	Tktl2 NCBI RGD Ensembl Show fit	transketolase-like 2
chr4_-_62840357 Show fit	16.61	ENSRNOT00000059892	Slc13a4 NCBI RGD Ensembl Show fit	solute carrier family 13 member 4
chr10_+_92245442 Show fit	16.53	ENSRNOT00000006808	Sppl2c NCBI RGD Ensembl Show fit	signal peptide peptidase like 2C
chr2_-_132301073 Show fit	16.46	ENSRNOT00000058288	RGD1563562 NCBI RGD Ensembl Show fit	similar to GTPase activating protein testicular GAP1
chr20_-_10386663 Show fit	16.42	ENSRNOT00000045275 ENSRNOT00000042432	Cbs NCBI RGD Ensembl Show fit	cystathionine beta synthase
chr4_-_176026133 Show fit	16.20	ENSRNOT00000043374 ENSRNOT00000046598	Slco1a4 NCBI RGD Ensembl Show fit	solute carrier organic anion transporter family, member 1a4
chr6_+_104718512 Show fit	15.93	ENSRNOT00000007947	Smoc1 NCBI RGD Ensembl Show fit	SPARC related modular calcium binding 1
chr16_-_39970532 Show fit	15.79	ENSRNOT00000071331	Spata4 NCBI RGD Ensembl Show fit	spermatogenesis associated 4
chr6_+_111180108 Show fit	15.66	ENSRNOT00000082027	Gstz1 NCBI RGD Ensembl Show fit	glutathione S-transferase zeta 1
chr4_+_70776046 Show fit	15.64	ENSRNOT00000040403	Prss1 NCBI RGD Ensembl Show fit	protease, serine 1
chr17_+_15194262 Show fit	15.63	ENSRNOT00000073070	AABR07072539.1 NCBI RGD Ensembl Show fit
chrX_+_83570346 Show fit	15.63	ENSRNOT00000045603	Ube2d4l1 NCBI RGD Ensembl Show fit	ubiquitin-conjugating enzyme E2D 4 like 1
chr1_-_198267093 Show fit	15.57	ENSRNOT00000047477	RGD1563217 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 4930451I11
chr19_+_52077501 Show fit	15.40	ENSRNOT00000079240	Osgin1 NCBI RGD Ensembl Show fit	oxidative stress induced growth inhibitor 1
chr18_-_45380730 Show fit	15.24	ENSRNOT00000037904	Pudp NCBI RGD Ensembl Show fit	pseudouridine 5'-phosphatase
chr1_+_167937026 Show fit	15.22	ENSRNOT00000020655	Olr57 NCBI RGD Ensembl Show fit	olfactory receptor 57
chr10_+_83954279 Show fit	15.11	ENSRNOT00000006594	Ttll6 NCBI RGD Ensembl Show fit	tubulin tyrosine ligase like 6
chr3_-_3266260 Show fit	15.10	ENSRNOT00000034538	Glt6d1 NCBI RGD Ensembl Show fit	glycosyltransferase 6 domain containing 1
chr1_-_107385257 Show fit	14.97	ENSRNOT00000074296	Ccdc179 NCBI RGD Ensembl Show fit	coiled-coil domain containing 179
chr9_-_79630452 Show fit	14.88	ENSRNOT00000078125 ENSRNOT00000086044 ENSRNOT00000089283	Pecr NCBI RGD Ensembl Show fit	peroxisomal trans-2-enoyl-CoA reductase
chr4_+_52129556 Show fit	14.82	ENSRNOT00000009435	Hyal6 NCBI RGD Ensembl Show fit	hyaluronoglucosaminidase 6
chr16_-_54533871 Show fit	14.74	ENSRNOT00000015144	LOC100910977 NCBI RGD Ensembl Show fit	disintegrin and metalloproteinase domain-containing protein 25-like
chr4_+_10295122 Show fit	14.66	ENSRNOT00000017374	Ccdc146 NCBI RGD Ensembl Show fit	coiled-coil domain containing 146
chr4_-_161091010 Show fit	14.61	ENSRNOT00000043708	Senp17 NCBI RGD Ensembl Show fit	Sumo1/sentrin/SMT3 specific peptidase 17
chr12_-_18274515 Show fit	14.59	ENSRNOT00000078075	LOC100361826 NCBI RGD Ensembl Show fit	sialophorin-like
chrX_+_90588124 Show fit	14.59	ENSRNOT00000045685	Tgif2lx2 NCBI RGD Ensembl Show fit	TGFB-induced factor homeobox 2-like, X-linked 2
chr4_+_157107469 Show fit	14.58	ENSRNOT00000015678	C1rl NCBI RGD Ensembl Show fit	complement C1r subcomponent like
chrX_-_139263974 Show fit	14.56	ENSRNOT00000050147	MGC114492 NCBI RGD Ensembl Show fit	similar to melanoma antigen family A, 5
chr2_-_185303610 Show fit	14.51	ENSRNOT00000093479 ENSRNOT00000046286	NEWGENE_1592020 NCBI RGD Ensembl Show fit	protease, serine 48
chr17_-_42127678 Show fit	14.42	ENSRNOT00000024196	Gpld1 NCBI RGD Ensembl Show fit	glycosylphosphatidylinositol specific phospholipase D1
chrX_-_98095663 Show fit	14.38	ENSRNOT00000004491	Rbm31y NCBI RGD Ensembl Show fit	RNA binding motif 31, Y-linked
chr9_+_35289443 Show fit	14.36	ENSRNOT00000037765 ENSRNOT00000060503	Spata31e1 NCBI RGD Ensembl Show fit	SPATA31 subfamily E, member 1
chr1_-_102780381 Show fit	14.23	ENSRNOT00000080132	Saa4 NCBI RGD Ensembl Show fit	serum amyloid A4
chr7_-_54855557 Show fit	14.17	ENSRNOT00000039475	Glipr1l1 NCBI RGD Ensembl Show fit	GLI pathogenesis-related 1 like 1
chr16_+_51730452 Show fit	13.96	ENSRNOT00000078614	Adam34l NCBI RGD Ensembl Show fit	a disintegrin and metalloprotease domain 34-like
chr7_+_140781799 Show fit	13.93	ENSRNOT00000087932	Dnajc22 NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member C22
chr1_+_196737627 Show fit	13.90	ENSRNOT00000066652	LOC100271845 NCBI RGD Ensembl Show fit	hypothetical protein LOC100271845
chr1_-_227359809 Show fit	13.90	ENSRNOT00000088080	1700025F22Rik NCBI RGD Ensembl Show fit	RIKEN cDNA 1700025F22 gene
chr1_-_153096269 Show fit	13.78	ENSRNOT00000022578	Tmem135 NCBI RGD Ensembl Show fit	transmembrane protein 135
chrX_-_152367861 Show fit	13.68	ENSRNOT00000089414	LOC103690371 NCBI RGD Ensembl Show fit	melanoma-associated antigen 10-like
chr8_+_4085829 Show fit	13.67	ENSRNOT00000031286	Actl9b NCBI RGD Ensembl Show fit	actin-like 9b
chr15_-_5467047 Show fit	13.65	ENSRNOT00000042743	Spetex-2F NCBI RGD Ensembl Show fit	Spetex-2F protein
chrX_-_135761025 Show fit	13.59	ENSRNOT00000033044	RGD1564955 NCBI RGD Ensembl Show fit	similar to fibrous sheath interacting protein 2
chr8_+_81766041 Show fit	13.59	ENSRNOT00000032280	Onecut1 NCBI RGD Ensembl Show fit	one cut homeobox 1
chr6_+_127282466 Show fit	13.49	ENSRNOT00000012124	Otub2 NCBI RGD Ensembl Show fit	OTU deubiquitinase, ubiquitin aldehyde binding 2
chr11_+_88095170 Show fit	13.29	ENSRNOT00000041557	Ccdc116 NCBI RGD Ensembl Show fit	coiled-coil domain containing 116
chr1_+_91363492 Show fit	13.13	ENSRNOT00000014517	Cebpa NCBI RGD Ensembl Show fit	CCAAT/enhancer binding protein alpha
chr6_-_107461041 Show fit	13.11	ENSRNOT00000058127	Heatr4 NCBI RGD Ensembl Show fit	HEAT repeat containing 4
chr14_+_85814824 Show fit	13.04	ENSRNOT00000090046 ENSRNOT00000083756	Ankrd36 NCBI RGD Ensembl Show fit	ankyrin repeat domain 36
chr14_-_108284619 Show fit	13.02	ENSRNOT00000078814	LOC690352 NCBI RGD Ensembl Show fit	hypothetical protein LOC690352
chrX_+_97074710 Show fit	12.92	ENSRNOT00000044379	RGD1561230 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 4921511C20 gene
chr1_-_81550598 Show fit	12.90	ENSRNOT00000051671	RGD1564380 NCBI RGD Ensembl Show fit	similar to BC049730 protein
chr4_-_160803558 Show fit	12.85	ENSRNOT00000049542	Senp18 NCBI RGD Ensembl Show fit	Sumo1/sentrin/SMT3 specific peptidase 18
chr5_+_162127810 Show fit	12.79	ENSRNOT00000038858	Pramef27 NCBI RGD Ensembl Show fit	PRAME family member 27
chr9_+_4107246 Show fit	12.73	ENSRNOT00000078212	AABR07066160.1 NCBI RGD Ensembl Show fit
chr5_+_165415136 Show fit	12.70	ENSRNOT00000016317 ENSRNOT00000079407	Masp2 NCBI RGD Ensembl Show fit	mannan-binding lectin serine peptidase 2
chr9_+_95285592 Show fit	12.70	ENSRNOT00000063853	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chrX_+_130007087 Show fit	12.58	ENSRNOT00000074996	Tex13c NCBI RGD Ensembl Show fit	TEX13 family member C
chr9_+_95233957 Show fit	12.55	ENSRNOT00000071003	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chr1_+_101603222 Show fit	12.46	ENSRNOT00000033278	Izumo1 NCBI RGD Ensembl Show fit	izumo sperm-egg fusion 1
chr17_+_89452814 Show fit	12.26	ENSRNOT00000058760	RGD1561231 NCBI RGD Ensembl Show fit	similar to MAP/microtubule affinity-regulating kinase 4 (MAP/microtubule affinity-regulating kinase like 1)
chr4_-_6449949 Show fit	12.19	ENSRNOT00000062026	Galntl5 NCBI RGD Ensembl Show fit	polypeptide N-acetylgalactosaminyltransferase-like 5
chr1_+_282694906 Show fit	12.19	ENSRNOT00000074303	Ces2c NCBI RGD Ensembl Show fit	carboxylesterase 2C
chr10_+_88620655 Show fit	12.18	ENSRNOT00000055248	Hspb9 NCBI RGD Ensembl Show fit	heat shock protein family B (small) member 9
chr20_-_11764233 Show fit	12.08	ENSRNOT00000001638	Pttg1ip NCBI RGD Ensembl Show fit	pituitary tumor-transforming 1 interacting protein
chr14_-_108285008 Show fit	12.06	ENSRNOT00000087501	LOC690352 NCBI RGD Ensembl Show fit	hypothetical protein LOC690352
chr1_-_104024682 Show fit	11.94	ENSRNOT00000056081	Mrgprx1 NCBI RGD Ensembl Show fit	MAS-related GPR, member X1
chr4_-_30556814 Show fit	11.91	ENSRNOT00000012760	Pdk4 NCBI RGD Ensembl Show fit	pyruvate dehydrogenase kinase 4
chr6_+_2886764 Show fit	11.86	ENSRNOT00000023114	Ttc39d NCBI RGD Ensembl Show fit	tetratricopeptide repeat domain 39D
chr2_-_137153551 Show fit	11.86	ENSRNOT00000083443	AABR07010476.1 NCBI RGD Ensembl Show fit
chr3_-_14571640 Show fit	11.68	ENSRNOT00000060013	Ggta1l1 NCBI RGD Ensembl Show fit	glycoprotein, alpha-galactosyltransferase 1-like 1
chr10_-_75202030 Show fit	11.67	ENSRNOT00000050349	Olr1522 NCBI RGD Ensembl Show fit	olfactory receptor 1522
chr1_+_102924059 Show fit	11.67	ENSRNOT00000078137	AC099150.1 NCBI RGD Ensembl Show fit
chr16_+_72011870 Show fit	11.65	ENSRNOT00000092198	Adam5 NCBI RGD Ensembl Show fit	ADAM metallopeptidase domain 5
chr10_+_34414854 Show fit	11.65	ENSRNOT00000074980	LOC684471 NCBI RGD Ensembl Show fit	similar to olfactory receptor 1394
chrX_-_61151601 Show fit	11.59	ENSRNOT00000004132	Mageb4 NCBI RGD Ensembl Show fit	melanoma antigen family B, 4
chr15_+_51034620 Show fit	11.46	ENSRNOT00000032826	Nkx2-6 NCBI RGD Ensembl Show fit	NK2 homeobox 6
chr2_-_196415530 Show fit	11.40	ENSRNOT00000064238	RGD1359334 NCBI RGD Ensembl Show fit	similar to hypothetical protein FLJ20519
chr10_+_59894340 Show fit	11.38	ENSRNOT00000080446	Spata22 NCBI RGD Ensembl Show fit	spermatogenesis associated 22
chr1_+_190462327 Show fit	11.37	ENSRNOT00000030732	LOC691519 NCBI RGD Ensembl Show fit	similar to ankyrin repeat domain 26
chr6_+_84293402 Show fit	11.35	ENSRNOT00000072657	LOC108351365 NCBI RGD Ensembl Show fit	uncharacterized LOC108351365
chr6_-_108167185 Show fit	11.35	ENSRNOT00000015545	Aldh6a1 NCBI RGD Ensembl Show fit	aldehyde dehydrogenase 6 family, member A1
chr10_-_105412627 Show fit	11.35	ENSRNOT00000034817	Qrich2 NCBI RGD Ensembl Show fit	glutamine rich 2
chr10_+_87782376 Show fit	11.32	ENSRNOT00000017415	LOC680396 NCBI RGD Ensembl Show fit	hypothetical protein LOC680396
chr16_+_51748970 Show fit	11.29	ENSRNOT00000059182	Adam26a NCBI RGD Ensembl Show fit	a disintegrin and metallopeptidase domain 26A
chr7_-_22943159 Show fit	11.22	ENSRNOT00000047547	Vom2r57 NCBI RGD Ensembl Show fit	vomeronasal 2 receptor, 57
chr15_+_18322327 Show fit	11.13	ENSRNOT00000009650	Fam3d NCBI RGD Ensembl Show fit	family with sequence similarity 3, member D
chr8_-_115274165 Show fit	11.12	ENSRNOT00000056386	LOC102550160 NCBI RGD Ensembl Show fit	IQ domain-containing protein F5-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Dmc1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
17.1	51.2	GO:0051977	lysophospholipid transport(GO:0051977)
16.1	64.3	GO:0046951	ketone body biosynthetic process(GO:0046951)
15.7	78.6	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
13.7	369.7	GO:0019373	epoxygenase P450 pathway(GO:0019373)
13.0	39.1	GO:0034769	basement membrane disassembly(GO:0034769)
12.9	38.7	GO:0010034	response to acetate(GO:0010034)
12.2	36.6	GO:0006579	amino-acid betaine catabolic process(GO:0006579)
12.1	48.5	GO:0019483	beta-alanine biosynthetic process(GO:0019483)
9.8	29.3	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
9.6	38.4	GO:0046439	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
9.3	120.6	GO:0052695	cellular glucuronidation(GO:0052695)
7.9	23.7	GO:0001905	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
7.8	23.4	GO:1903173	phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
7.2	57.8	GO:0006559	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
6.9	27.6	GO:0098707	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
5.7	11.3	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
5.5	33.2	GO:0046687	response to chromate(GO:0046687)
4.9	24.5	GO:0043152	induction of bacterial agglutination(GO:0043152)
4.8	14.4	GO:0010986	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986) cellular response to iron(II) ion(GO:0071282)
4.6	18.6	GO:0060468	prevention of polyspermy(GO:0060468)
4.6	63.8	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
4.3	60.0	GO:0001867	complement activation, lectin pathway(GO:0001867)
4.3	29.9	GO:0009812	flavonoid metabolic process(GO:0009812)
4.2	20.8	GO:0009758	carbohydrate utilization(GO:0009758) fructose transport(GO:0015755)
4.0	20.0	GO:0071400	cellular response to oleic acid(GO:0071400)
4.0	55.4	GO:0043252	sodium-independent organic anion transport(GO:0043252)
3.6	7.2	GO:0031448	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
3.3	6.7	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
3.3	16.6	GO:0033384	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384)
3.2	6.4	GO:0021502	neural fold elevation formation(GO:0021502)
3.1	9.4	GO:0061228	mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
3.0	9.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
3.0	11.9	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
2.9	17.7	GO:0019659	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
2.9	20.5	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
2.9	20.4	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
2.9	8.7	GO:2000424	T-helper 1 cell lineage commitment(GO:0002296) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
2.9	22.8	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
2.8	2.8	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
2.8	30.5	GO:0051132	NK T cell activation(GO:0051132)
2.8	22.0	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
2.7	10.9	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
2.7	2.7	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
2.7	19.0	GO:0044539	long-chain fatty acid import(GO:0044539)
2.7	8.0	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
2.6	10.6	GO:1904158	axonemal central apparatus assembly(GO:1904158)
2.6	7.9	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
2.6	7.9	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
2.6	36.0	GO:0035634	response to stilbenoid(GO:0035634)
2.6	17.9	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
2.5	7.6	GO:1905146	lysosomal protein catabolic process(GO:1905146)
2.4	26.8	GO:0030259	lipid glycosylation(GO:0030259)
2.4	7.1	GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
2.3	9.4	GO:0001579	medium-chain fatty acid transport(GO:0001579)
2.2	6.6	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378)
2.2	6.6	GO:0097498	endothelial tube lumen extension(GO:0097498)
2.2	8.7	GO:0052314	phytoalexin metabolic process(GO:0052314)
2.2	28.2	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.1	42.7	GO:0035404	histone-serine phosphorylation(GO:0035404)
2.1	18.8	GO:0038161	prolactin signaling pathway(GO:0038161)
2.0	6.1	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
2.0	6.1	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
1.9	5.8	GO:0044375	regulation of peroxisome size(GO:0044375)
1.9	11.6	GO:0060455	negative regulation of gastric acid secretion(GO:0060455)
1.8	11.1	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
1.8	98.5	GO:0006953	acute-phase response(GO:0006953)
1.7	1.7	GO:1904444	regulation of establishment of Sertoli cell barrier(GO:1904444)
1.7	9.9	GO:0006528	asparagine metabolic process(GO:0006528)
1.5	13.8	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.5	4.6	GO:0043132	phospholipid transfer to membrane(GO:0006649) NAD transport(GO:0043132) regulation of bleb assembly(GO:1904170)
1.5	16.8	GO:0019321	pentose metabolic process(GO:0019321)
1.5	7.5	GO:0021650	vestibulocochlear nerve formation(GO:0021650)
1.5	16.5	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
1.4	36.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
1.4	121.9	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
1.4	22.8	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866)
1.4	14.1	GO:0018095	protein polyglutamylation(GO:0018095)
1.4	4.2	GO:0046099	guanine salvage(GO:0006178) GMP catabolic process(GO:0046038) guanine biosynthetic process(GO:0046099)
1.4	56.1	GO:0006805	xenobiotic metabolic process(GO:0006805)
1.4	4.2	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
1.4	11.1	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
1.4	6.9	GO:0009624	response to nematode(GO:0009624)
1.4	51.1	GO:0035036	sperm-egg recognition(GO:0035036)
1.4	15.1	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
1.4	5.4	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
1.3	28.2	GO:0006958	complement activation, classical pathway(GO:0006958)
1.3	5.3	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
1.3	5.3	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
1.3	42.0	GO:0019369	arachidonic acid metabolic process(GO:0019369)
1.3	5.2	GO:1901314	negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
1.3	7.7	GO:0023021	termination of signal transduction(GO:0023021)
1.3	34.2	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
1.2	22.1	GO:0010818	T cell chemotaxis(GO:0010818)
1.2	3.5	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
1.1	2.3	GO:0071288	cellular response to mercury ion(GO:0071288)
1.1	17.1	GO:0001675	acrosome assembly(GO:0001675)
1.1	8.5	GO:0032571	response to vitamin K(GO:0032571)
1.1	6.4	GO:0051182	coenzyme transport(GO:0051182)
1.0	3.1	GO:0015793	glycerol transport(GO:0015793)
1.0	11.4	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
1.0	8.1	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.0	4.8	GO:0015860	purine nucleoside transmembrane transport(GO:0015860)
0.9	8.3	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.9	3.7	GO:1901318	negative regulation of sperm motility(GO:1901318)
0.9	2.7	GO:0021678	third ventricle development(GO:0021678)
0.9	3.6	GO:0033026	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.9	5.5	GO:2000847	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.9	1.8	GO:0006751	glutathione catabolic process(GO:0006751)
0.9	7.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.9	0.9	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.9	2.6	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.8	5.8	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.8	5.0	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.8	5.8	GO:0030916	otic vesicle formation(GO:0030916)
0.8	3.2	GO:0019516	lactate oxidation(GO:0019516)
0.8	10.3	GO:0071468	cellular response to acidic pH(GO:0071468)
0.8	18.4	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.8	6.9	GO:0033504	floor plate development(GO:0033504)
0.7	8.9	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.7	2.2	GO:1903719	regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.7	5.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.7	7.9	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.7	10.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.7	3.6	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.7	12.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.7	2.1	GO:0008594	photoreceptor cell morphogenesis(GO:0008594) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.7	8.4	GO:0010040	response to iron(II) ion(GO:0010040)
0.7	5.5	GO:0002759	regulation of antimicrobial humoral response(GO:0002759)
0.7	6.9	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.7	4.0	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.6	4.5	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.6	9.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.6	2.6	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.6	2.5	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.6	3.7	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.6	2.5	GO:1903677	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.6	2.4	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.6	3.6	GO:1904117	cellular response to vasopressin(GO:1904117)
0.6	2.4	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.6	6.5	GO:0010603	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.6	3.0	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529) gamma-aminobutyric acid receptor clustering(GO:0097112) receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.6	2.9	GO:1990918	meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.6	7.9	GO:1900004	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.6	1.7	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.6	5.5	GO:0061734	parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.6	7.8	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.5	2.7	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.5	12.5	GO:0030574	collagen catabolic process(GO:0030574)
0.5	2.7	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.5	2.7	GO:0021769	orbitofrontal cortex development(GO:0021769)
0.5	26.8	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.5	4.7	GO:0030049	muscle filament sliding(GO:0030049)
0.5	10.4	GO:0097154	GABAergic neuron differentiation(GO:0097154)
0.5	5.1	GO:0006465	signal peptide processing(GO:0006465)
0.5	5.7	GO:0034063	stress granule assembly(GO:0034063)
0.5	1.5	GO:1900114	positive regulation of histone H3-K9 dimethylation(GO:1900111) positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.5	17.5	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.5	4.3	GO:0034982	mitochondrial protein processing(GO:0034982)
0.5	3.3	GO:0046549	retinal cone cell development(GO:0046549)
0.5	4.6	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.5	4.5	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.5	5.0	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.4	4.9	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.4	3.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.4	3.0	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.4	0.8	GO:1904580	regulation of intracellular mRNA localization(GO:1904580)
0.4	2.5	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.4	3.3	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.4	2.5	GO:1990928	cellular response to rapamycin(GO:0072752) response to amino acid starvation(GO:1990928)
0.4	1.2	GO:0044726	protection of DNA demethylation of female pronucleus(GO:0044726)
0.4	2.8	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.4	4.4	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.4	15.6	GO:0031018	endocrine pancreas development(GO:0031018)
0.4	3.2	GO:0000733	DNA strand renaturation(GO:0000733)
0.4	4.6	GO:0006108	malate metabolic process(GO:0006108)
0.4	2.3	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.4	1.1	GO:0018094	protein polyglycylation(GO:0018094)
0.4	3.0	GO:0030823	regulation of cGMP metabolic process(GO:0030823)
0.4	1.5	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.4	7.8	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.4	4.5	GO:0046068	cGMP metabolic process(GO:0046068)
0.4	4.8	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.4	2.2	GO:0033182	regulation of histone ubiquitination(GO:0033182)
0.4	7.7	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.4	17.1	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.4	1.4	GO:0010749	regulation of nitric oxide mediated signal transduction(GO:0010749)
0.4	2.5	GO:2000020	positive regulation of male gonad development(GO:2000020)
0.4	2.5	GO:0015884	folic acid transport(GO:0015884)
0.3	3.1	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.3	2.8	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.3	9.0	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.3	2.3	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3	3.9	GO:0006265	DNA topological change(GO:0006265)
0.3	6.1	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3	2.8	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.3	3.6	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.3	4.5	GO:0043248	proteasome assembly(GO:0043248)
0.3	4.2	GO:0051601	exocyst localization(GO:0051601)
0.3	2.1	GO:0046884	follicle-stimulating hormone secretion(GO:0046884)
0.3	3.8	GO:0072711	cellular response to hydroxyurea(GO:0072711)
0.3	1.8	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3	2.0	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.3	364.5	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3	11.0	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.3	1.6	GO:0001835	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.3	4.0	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.3	2.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.3	2.8	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.3	5.6	GO:2000678	negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.3	1.3	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
0.3	0.8	GO:0009227	nucleotide-sugar catabolic process(GO:0009227)
0.3	4.6	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.2	7.7	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.2	6.9	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2	3.6	GO:0031034	myosin filament assembly(GO:0031034)
0.2	4.6	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.2	4.4	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
0.2	0.7	GO:2000523	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2	1.8	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.2	4.1	GO:0006020	inositol metabolic process(GO:0006020)
0.2	6.2	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.2	0.9	GO:0051692	cellular oligosaccharide metabolic process(GO:0051691) cellular oligosaccharide catabolic process(GO:0051692) regulation of exo-alpha-sialidase activity(GO:1903015)
0.2	2.6	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.2	3.8	GO:2000778	positive regulation of interleukin-6 secretion(GO:2000778)
0.2	1.5	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.2	1.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2	13.2	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.2	3.3	GO:0050667	homocysteine metabolic process(GO:0050667)
0.2	12.2	GO:0071346	cellular response to interferon-gamma(GO:0071346)
0.2	0.8	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2	2.4	GO:0051764	actin crosslink formation(GO:0051764)
0.2	6.7	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.2	0.8	GO:0001555	oocyte growth(GO:0001555)
0.2	0.6	GO:0036451	cap mRNA methylation(GO:0036451)
0.2	0.6	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.2	1.1	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.2	1.6	GO:0032790	ribosome disassembly(GO:0032790)
0.2	1.0	GO:0048496	maintenance of organ identity(GO:0048496)
0.2	0.9	GO:0019563	glycerol catabolic process(GO:0019563)
0.2	1.3	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.2	3.3	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.2	12.0	GO:0006342	chromatin silencing(GO:0006342)
0.2	1.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2	2.1	GO:0070255	regulation of mucus secretion(GO:0070255)
0.2	1.6	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.2	3.6	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.2	1.2	GO:0010578	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1	7.9	GO:0032024	positive regulation of insulin secretion(GO:0032024)
0.1	4.1	GO:0003009	skeletal muscle contraction(GO:0003009)
0.1	1.9	GO:0007602	phototransduction(GO:0007602)
0.1	1.0	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1	1.3	GO:0090084	chaperone cofactor-dependent protein refolding(GO:0070389) negative regulation of inclusion body assembly(GO:0090084)
0.1	3.7	GO:1900047	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1	3.1	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1	1.1	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.1	1.4	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.1	3.9	GO:0042755	eating behavior(GO:0042755)
0.1	0.9	GO:0060263	regulation of respiratory burst(GO:0060263)
0.1	0.8	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1	2.0	GO:0009435	NAD biosynthetic process(GO:0009435)
0.1	2.2	GO:0021854	hypothalamus development(GO:0021854)
0.1	4.6	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1	15.2	GO:0030178	negative regulation of Wnt signaling pathway(GO:0030178)
0.1	3.0	GO:0032873	negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1	0.4	GO:0014732	skeletal muscle atrophy(GO:0014732)
0.1	0.8	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1	3.4	GO:0005977	glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1	0.9	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1	3.3	GO:0044458	motile cilium assembly(GO:0044458)
0.1	0.3	GO:0080154	regulation of fertilization(GO:0080154)
0.1	2.2	GO:0006458	'de novo' protein folding(GO:0006458)
0.1	1.1	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1	2.1	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.1	0.8	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.1	1.0	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234)
0.1	1.5	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.1	0.8	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	20.0	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.1	1.3	GO:0019395	fatty acid oxidation(GO:0019395)
0.1	1.2	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1	0.7	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	12.2	GO:0007286	spermatid development(GO:0007286)
0.1	2.7	GO:0018345	protein palmitoylation(GO:0018345)
0.1	0.6	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.1	7.5	GO:0016579	protein deubiquitination(GO:0016579)
0.1	6.4	GO:0045667	regulation of osteoblast differentiation(GO:0045667)
0.1	0.9	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.1	1.8	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.1	7.3	GO:0006457	protein folding(GO:0006457)
0.1	0.9	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.1	0.5	GO:1900040	interleukin-2 secretion(GO:0070970) regulation of interleukin-2 secretion(GO:1900040)
0.1	2.4	GO:0030858	positive regulation of epithelial cell differentiation(GO:0030858)
0.1	3.4	GO:0007586	digestion(GO:0007586)
0.1	4.6	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	2.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.4	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	1.3	GO:0033280	response to vitamin D(GO:0033280)
0.0	0.5	GO:0008206	bile acid metabolic process(GO:0008206)
0.0	0.7	GO:0071625	vocalization behavior(GO:0071625)
0.0	0.6	GO:0031572	mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.0	0.5	GO:0046037	GMP metabolic process(GO:0046037)
0.0	1.4	GO:0006497	protein lipidation(GO:0006497)
0.0	0.9	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.1	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.0	0.7	GO:0031648	protein destabilization(GO:0031648)
0.0	1.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.7	GO:0006284	base-excision repair(GO:0006284)
0.0	0.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	1.0	GO:0050909	sensory perception of taste(GO:0050909)
0.0	0.6	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.3	GO:0010453	regulation of cell fate commitment(GO:0010453)
0.0	0.3	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.8	GO:0006414	translational elongation(GO:0006414)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.5	GO:0000186	activation of MAPKK activity(GO:0000186)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.1	51.2	GO:0045179	apical cortex(GO:0045179)
4.6	27.6	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
4.4	13.1	GO:0036488	CHOP-C/EBP complex(GO:0036488)
3.4	23.7	GO:0005579	membrane attack complex(GO:0005579)
3.2	18.9	GO:0097598	sperm cytoplasmic droplet(GO:0097598)
3.1	24.5	GO:0005577	fibrinogen complex(GO:0005577)
2.6	18.2	GO:0060205	cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
2.5	7.6	GO:0031166	integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
2.5	45.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
2.4	16.5	GO:0098553	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
2.1	10.6	GO:1990716	axonemal central apparatus(GO:1990716)
1.8	27.3	GO:0035686	sperm fibrous sheath(GO:0035686)
1.4	4.3	GO:0005745	m-AAA complex(GO:0005745)
1.4	4.3	GO:0043159	acrosomal matrix(GO:0043159)
1.3	6.7	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
1.3	24.7	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
1.3	8.8	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
1.2	3.6	GO:1990723	cytoplasmic periphery of the nuclear pore complex(GO:1990723)
1.2	28.6	GO:0034364	high-density lipoprotein particle(GO:0034364)
1.2	131.5	GO:0072562	blood microparticle(GO:0072562)
1.2	64.3	GO:0009925	basal plasma membrane(GO:0009925)
1.0	4.2	GO:0035339	SPOTS complex(GO:0035339)
1.0	7.7	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
1.0	7.6	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.9	6.2	GO:0005683	U7 snRNP(GO:0005683)
0.9	7.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.9	12.3	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.9	5.1	GO:0005787	signal peptidase complex(GO:0005787)
0.8	3.3	GO:0030478	actin cap(GO:0030478)
0.8	51.8	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.8	2.3	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.8	55.6	GO:0045095	keratin filament(GO:0045095)
0.8	7.5	GO:0031298	replication fork protection complex(GO:0031298)
0.7	18.7	GO:0002080	acrosomal membrane(GO:0002080)
0.7	15.6	GO:0031528	microvillus membrane(GO:0031528)
0.7	79.9	GO:0001669	acrosomal vesicle(GO:0001669)
0.7	2.2	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.7	2.9	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.7	2.8	GO:0005859	muscle myosin complex(GO:0005859)
0.7	8.3	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.7	17.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.6	1.3	GO:0099522	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.6	46.6	GO:0005581	collagen trimer(GO:0005581)
0.6	6.1	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.6	2.4	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.6	3.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.6	1.7	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.6	4.6	GO:0032059	bleb(GO:0032059)
0.6	2.3	GO:0031021	interphase microtubule organizing center(GO:0031021)
0.6	11.8	GO:0005922	connexon complex(GO:0005922)
0.6	438.2	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.5	2.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.5	41.5	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.5	4.5	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.5	4.0	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.5	2.3	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.5	3.6	GO:0005826	actomyosin contractile ring(GO:0005826)
0.4	51.7	GO:0016363	nuclear matrix(GO:0016363)
0.4	1.8	GO:0035363	histone locus body(GO:0035363)
0.4	9.2	GO:0046930	pore complex(GO:0046930)
0.4	2.5	GO:0031931	TORC1 complex(GO:0031931)
0.4	3.1	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.4	7.3	GO:0043196	varicosity(GO:0043196)
0.4	1.5	GO:0005638	lamin filament(GO:0005638)
0.3	4.1	GO:0005861	troponin complex(GO:0005861)
0.3	1.0	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
0.3	5.4	GO:0001520	outer dense fiber(GO:0001520)
0.3	0.7	GO:0042382	paraspeckles(GO:0042382)
0.3	4.0	GO:0060091	kinocilium(GO:0060091)
0.3	0.9	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.3	0.9	GO:0008537	proteasome activator complex(GO:0008537)
0.3	6.9	GO:0042588	zymogen granule(GO:0042588)
0.3	2.3	GO:0098839	postsynaptic density membrane(GO:0098839)
0.3	7.6	GO:0031430	M band(GO:0031430)
0.3	2.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.2	3.0	GO:0032797	SMN complex(GO:0032797)
0.2	4.1	GO:0005916	fascia adherens(GO:0005916)
0.2	14.2	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2	7.9	GO:0031941	filamentous actin(GO:0031941)
0.2	1.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2	1.0	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.2	4.7	GO:0019013	viral nucleocapsid(GO:0019013)
0.2	2.5	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.2	11.0	GO:0005882	intermediate filament(GO:0005882)
0.2	3.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.2	6.6	GO:0032421	stereocilium bundle(GO:0032421)
0.2	7.3	GO:0031526	brush border membrane(GO:0031526)
0.2	4.2	GO:0000145	exocyst(GO:0000145)
0.2	1.4	GO:0005869	dynactin complex(GO:0005869)
0.2	0.9	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2	1.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.1	3.1	GO:0070822	Sin3-type complex(GO:0070822)
0.1	30.4	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	8.5	GO:0001750	photoreceptor outer segment(GO:0001750)
0.1	3.8	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	2.7	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.1	2.3	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	3.2	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1	1.4	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	0.7	GO:0036379	striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1	2.8	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	4.5	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	3.0	GO:0016235	aggresome(GO:0016235)
0.1	18.2	GO:0005759	mitochondrial matrix(GO:0005759)
0.1	1.0	GO:0030914	STAGA complex(GO:0030914)
0.1	4.9	GO:0005814	centriole(GO:0005814)
0.1	2.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	1.0	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1	2.1	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	5.8	GO:0036064	ciliary basal body(GO:0036064)
0.1	1.0	GO:0001741	XY body(GO:0001741)
0.1	0.6	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.1	1.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	4.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.8	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.7	GO:0060170	ciliary membrane(GO:0060170)
0.0	2.9	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	41.3	GO:0005615	extracellular space(GO:0005615)
0.0	1.3	GO:0005776	autophagosome(GO:0005776)
0.0	19.1	GO:0005739	mitochondrion(GO:0005739)
0.0	0.4	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
26.2	78.6	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
14.0	42.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
12.5	413.5	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391)
11.1	342.9	GO:0015020	glucuronosyltransferase activity(GO:0015020)
10.7	85.4	GO:0003996	acyl-CoA ligase activity(GO:0003996)
9.6	115.5	GO:0015245	fatty acid transporter activity(GO:0015245)
9.0	36.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
8.2	24.7	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
6.4	19.3	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
6.3	31.3	GO:0005534	galactose binding(GO:0005534)
6.0	36.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
6.0	18.0	GO:0004925	prolactin receptor activity(GO:0004925)
5.8	17.4	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
5.0	20.0	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
4.7	19.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
4.6	55.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
4.6	36.5	GO:0008172	S-methyltransferase activity(GO:0008172)
4.4	17.7	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
4.4	22.0	GO:0008453	alanine-glyoxylate transaminase activity(GO:0008453)
4.3	29.9	GO:0004062	aryl sulfotransferase activity(GO:0004062)
3.9	78.5	GO:0008395	steroid hydroxylase activity(GO:0008395)
3.7	14.9	GO:0019166	2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
3.6	10.9	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
3.4	13.5	GO:0019784	NEDD8-specific protease activity(GO:0019784)
3.3	16.6	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
3.3	19.7	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
3.2	34.7	GO:0039706	co-receptor binding(GO:0039706)
3.1	28.2	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
3.0	12.2	GO:0047619	acylcarnitine hydrolase activity(GO:0047619)
3.0	15.1	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
3.0	45.3	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
3.0	11.9	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
2.9	11.7	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
2.9	8.7	GO:0036468	aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
2.9	20.4	GO:0070095	fructose-6-phosphate binding(GO:0070095)
2.8	39.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
2.8	19.4	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
2.5	10.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
2.5	7.4	GO:0004159	dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
2.4	7.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
2.3	20.8	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
2.2	6.7	GO:0046911	metal chelating activity(GO:0046911)
2.2	6.6	GO:0017042	glycosylceramidase activity(GO:0017042)
2.2	8.7	GO:0005136	interleukin-4 receptor binding(GO:0005136)
2.1	6.2	GO:0071209	histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
2.0	12.3	GO:0004565	beta-galactosidase activity(GO:0004565)
2.0	16.2	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
1.8	14.4	GO:0004630	phospholipase D activity(GO:0004630)
1.8	16.2	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.8	5.4	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.7	36.0	GO:0034185	apolipoprotein binding(GO:0034185)
1.7	13.4	GO:0047134	protein-disulfide reductase activity(GO:0047134)
1.7	10.0	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
1.7	5.0	GO:0004522	ribonuclease A activity(GO:0004522)
1.6	9.8	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
1.6	3.2	GO:0004457	lactate dehydrogenase activity(GO:0004457)
1.6	6.4	GO:0042806	fucose binding(GO:0042806)
1.5	6.2	GO:0000829	inositol heptakisphosphate kinase activity(GO:0000829)
1.5	4.6	GO:0045550	geranylgeranyl reductase activity(GO:0045550) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
1.5	4.5	GO:0047708	biotinidase activity(GO:0047708)
1.5	37.2	GO:0005540	hyaluronic acid binding(GO:0005540)
1.5	14.8	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
1.5	13.1	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013)
1.4	8.5	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
1.4	28.2	GO:0008199	ferric iron binding(GO:0008199)
1.4	8.3	GO:0086059	voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
1.3	5.3	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
1.3	7.8	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
1.3	5.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
1.3	6.4	GO:0051185	coenzyme transporter activity(GO:0051185)
1.3	12.7	GO:0001846	opsonin binding(GO:0001846)
1.2	6.2	GO:0051373	FATZ binding(GO:0051373)
1.2	6.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
1.2	3.6	GO:0005135	interleukin-3 receptor binding(GO:0005135)
1.2	7.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
1.2	4.8	GO:0005415	nucleoside:sodium symporter activity(GO:0005415)
1.2	18.9	GO:0004806	triglyceride lipase activity(GO:0004806)
1.2	12.8	GO:0008242	omega peptidase activity(GO:0008242)
1.2	3.5	GO:0004956	prostaglandin D receptor activity(GO:0004956)
1.2	4.6	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
1.1	7.7	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
1.1	4.4	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
1.1	5.4	GO:0015168	polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
1.0	4.1	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
1.0	24.6	GO:0046966	thyroid hormone receptor binding(GO:0046966)
1.0	6.1	GO:0043295	glutathione binding(GO:0043295)
1.0	8.1	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
1.0	4.0	GO:0002046	opsin binding(GO:0002046)
1.0	4.8	GO:1990254	keratin filament binding(GO:1990254)
1.0	7.6	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.9	107.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.9	2.7	GO:0046592	polyamine oxidase activity(GO:0046592)
0.9	4.5	GO:0001155	TFIIIA-class transcription factor binding(GO:0001155)
0.9	3.6	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.9	2.7	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.8	11.8	GO:0005243	gap junction channel activity(GO:0005243)
0.8	6.8	GO:0032184	SUMO polymer binding(GO:0032184)
0.8	6.4	GO:0070700	BMP receptor binding(GO:0070700)
0.8	14.3	GO:0005537	mannose binding(GO:0005537)
0.8	3.2	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.8	4.7	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.8	16.3	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.8	10.8	GO:0033038	bitter taste receptor activity(GO:0033038)
0.8	6.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.8	4.6	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.8	2.3	GO:0031770	growth hormone-releasing hormone receptor binding(GO:0031770)
0.8	2.3	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.7	20.9	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.7	20.4	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.7	2.9	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.7	2.8	GO:0030350	iron-responsive element binding(GO:0030350)
0.7	6.3	GO:0009881	photoreceptor activity(GO:0009881)
0.7	26.8	GO:0004364	glutathione transferase activity(GO:0004364)
0.7	17.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.7	83.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.7	9.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.6	133.3	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.6	2.5	GO:0051870	methotrexate binding(GO:0051870)
0.6	2.4	GO:0019776	Atg8 ligase activity(GO:0019776)
0.6	4.7	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828)
0.6	4.1	GO:0031014	troponin T binding(GO:0031014)
0.6	9.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.6	8.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.6	1.7	GO:0097677	STAT family protein binding(GO:0097677)
0.6	4.5	GO:0070513	death domain binding(GO:0070513)
0.6	2.2	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.6	8.3	GO:0005523	tropomyosin binding(GO:0005523)
0.6	1.7	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.5	3.3	GO:0032027	myosin light chain binding(GO:0032027)
0.5	2.7	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.5	3.2	GO:0009378	four-way junction helicase activity(GO:0009378)
0.5	36.0	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.5	4.6	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.5	2.5	GO:0004974	leukotriene receptor activity(GO:0004974)
0.5	16.8	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.5	3.8	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.5	3.7	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.5	2.8	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.5	1.8	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
0.4	9.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.4	4.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4	3.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.4	10.4	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.4	2.7	GO:0035375	zymogen binding(GO:0035375)
0.4	28.0	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.4	1.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.4	1.8	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.3	2.8	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.3	7.9	GO:0048038	quinone binding(GO:0048038)
0.3	1.0	GO:0042015	interleukin-20 binding(GO:0042015)
0.3	8.0	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3	6.9	GO:0015288	porin activity(GO:0015288)
0.3	2.3	GO:0045503	dynein light chain binding(GO:0045503)
0.3	2.6	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.3	2.5	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.3	1.8	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.3	2.4	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.3	2.6	GO:0016778	diphosphotransferase activity(GO:0016778)
0.3	0.9	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.3	3.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.3	2.5	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.3	2.5	GO:0008494	translation activator activity(GO:0008494)
0.3	344.1	GO:0004984	olfactory receptor activity(GO:0004984)
0.3	5.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.3	5.4	GO:0043274	phospholipase binding(GO:0043274)
0.3	2.1	GO:0034511	U3 snoRNA binding(GO:0034511)
0.3	3.1	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.3	2.6	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3	1.3	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2	5.0	GO:0017049	GTP-Rho binding(GO:0017049)
0.2	5.2	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.2	2.8	GO:0005536	glucose binding(GO:0005536)
0.2	0.8	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2	6.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.2	11.7	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.2	3.9	GO:0043531	ADP binding(GO:0043531)
0.2	0.6	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2	2.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2	1.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.2	10.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.2	0.7	GO:0000405	bubble DNA binding(GO:0000405)
0.2	1.6	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.2	1.0	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.2	24.5	GO:0005179	hormone activity(GO:0005179)
0.2	1.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	3.7	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	1.6	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.1	0.4	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	10.9	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1	1.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.1	0.8	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.1	14.3	GO:0052689	carboxylic ester hydrolase activity(GO:0052689)
0.1	8.1	GO:0005507	copper ion binding(GO:0005507)
0.1	2.7	GO:0050681	androgen receptor binding(GO:0050681)
0.1	5.3	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1	0.9	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	3.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1	2.4	GO:0000146	microfilament motor activity(GO:0000146)
0.1	3.5	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.1	4.0	GO:0005109	frizzled binding(GO:0005109)
0.1	0.7	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	1.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.1	2.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	6.3	GO:0009055	electron carrier activity(GO:0009055)
0.1	10.0	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.1	2.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	7.5	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1	10.7	GO:0005506	iron ion binding(GO:0005506)
0.1	0.5	GO:0032052	bile acid binding(GO:0032052)
0.1	1.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	1.8	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.1	9.3	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	2.7	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	5.1	GO:0072341	modified amino acid binding(GO:0072341)
0.1	1.6	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	1.0	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	2.8	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.1	3.7	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1	1.4	GO:0008374	O-acyltransferase activity(GO:0008374)
0.1	0.6	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	1.3	GO:0001671	ATPase activator activity(GO:0001671)
0.1	1.7	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.1	0.8	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.1	0.4	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	2.7	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.2	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	2.5	GO:0051087	chaperone binding(GO:0051087)
0.0	0.9	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.9	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	5.0	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0	0.4	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.7	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	1.1	GO:0008146	sulfotransferase activity(GO:0008146)
0.0	1.0	GO:0003727	single-stranded RNA binding(GO:0003727)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.5	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
1.1	18.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.9	43.7	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.7	40.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.5	8.9	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5	2.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4	25.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.4	35.7	PID CMYB PATHWAY	C-MYB transcription factor network
0.4	86.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4	7.7	PID TRAIL PATHWAY	TRAIL signaling pathway
0.4	21.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.3	18.8	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.3	11.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.3	3.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.2	10.2	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.2	5.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2	7.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	5.2	PID RAS PATHWAY	Regulation of Ras family activation
0.2	4.6	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.2	3.1	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.2	1.8	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	1.4	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.1	4.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	2.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	5.0	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	0.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	2.1	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	1.9	PID BARD1 PATHWAY	BARD1 signaling events
0.1	1.5	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.9	PID MYC PATHWAY	C-MYC pathway
0.0	0.4	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.4	PID TELOMERASE PATHWAY	Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.1	172.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
7.9	95.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
4.6	78.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
4.5	131.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
3.7	48.5	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
3.4	37.8	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
2.8	27.8	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
2.3	30.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
2.1	36.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
2.1	25.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
2.1	81.4	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
1.9	19.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
1.8	23.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
1.8	9.0	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
1.7	36.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
1.5	43.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.5	20.5	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
1.3	29.6	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
1.0	9.7	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
1.0	17.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.9	5.7	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.9	35.7	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.9	1.8	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.9	20.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.9	18.8	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.7	11.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.6	16.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.6	8.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.6	6.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.6	10.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.6	10.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.6	8.9	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.5	9.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.5	5.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.5	9.8	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.5	10.3	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.5	76.8	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.5	5.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.5	16.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.5	5.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.4	3.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.4	2.5	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.4	10.4	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.3	3.6	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3	31.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.3	4.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3	4.6	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.3	8.2	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.3	4.8	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.3	12.4	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.3	18.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.3	11.4	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.3	5.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	9.7	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.2	8.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.2	2.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.2	11.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.2	3.2	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.2	2.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	3.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	2.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	2.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	3.7	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	0.6	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	2.7	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	0.9	REACTOME OPSINS	Genes involved in Opsins
0.1	5.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	0.9	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.1	0.4	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	0.8	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	3.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.9	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.7	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.6	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	2.0	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation

Results for Dmc1

Z-value: 1.60

Motif logo

Transcription factors associated with Dmc1

Activity-expression correlation:

Activity profile of Dmc1 motif

Sorted Z-values of Dmc1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Dmc1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: