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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Cux1

Z-value: 1.76

Motif logo

Transcription factors associated with Cux1

Gene Symbol Gene ID Gene Info
ENSRNOG00000001424 cut-like homeobox 1
ENSRNOG00000059116 cut-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cux1rn6_v1_chr12_+_23151180_23151180-0.754.6e-58Click!

Activity profile of Cux1 motif

Sorted Z-values of Cux1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_83744238 73.62 ENSRNOT00000028249
cytochrome P450, family 2, subfamily a, polypeptide 1
chr1_-_148119857 73.40 ENSRNOT00000040325
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr14_+_22375955 64.22 ENSRNOT00000063915
ENSRNOT00000034784
UDP-glucuronosyltransferase 2 family, member 37
chr17_+_9736786 63.05 ENSRNOT00000081920
coagulation factor XII
chr5_-_78985990 57.22 ENSRNOT00000009248
alpha-1-microglobulin/bikunin precursor
chr14_+_20266891 55.97 ENSRNOT00000004174
group specific component
chr1_+_83711251 54.26 ENSRNOT00000028237
ENSRNOT00000092008
cytochrome P450, family 2, subfamily a, polypeptide 1
chr2_+_23289374 53.46 ENSRNOT00000090666
ENSRNOT00000032783
dimethylglycine dehydrogenase
chr4_-_161850875 53.17 ENSRNOT00000009467
pregnancy-zone protein
chr15_+_18451144 51.56 ENSRNOT00000010260
acyl-CoA oxidase 2
chr9_-_4945352 51.45 ENSRNOT00000082530
sulfotransferase family 1C member 3
chr4_-_115332052 50.04 ENSRNOT00000017643
C-type lectin domain family 4, member F
chr17_+_9736577 46.18 ENSRNOT00000066586
coagulation factor XII
chr10_+_65767053 45.18 ENSRNOT00000078897
vitronectin
chr17_-_69711689 44.72 ENSRNOT00000041925
aldo-keto reductase family 1, member C12
chr13_-_47397890 44.47 ENSRNOT00000005505
complement component 4 binding protein, beta
chr19_-_50220455 44.18 ENSRNOT00000079760
short chain dehydrogenase/reductase family 42E, member 1
chr6_-_127534247 43.11 ENSRNOT00000012500
serpin family A member 6
chr7_-_71139267 41.48 ENSRNOT00000065232
similar to Retinol dehydrogenase type II (RODH II) (29 k-protein)
chr1_+_147713892 41.10 ENSRNOT00000092985
ENSRNOT00000054742
ENSRNOT00000074103
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
chr4_-_50200328 40.19 ENSRNOT00000060530
aminoadipate-semialdehyde synthase
chr7_-_129970550 37.84 ENSRNOT00000055879
megalencephalic leukoencephalopathy with subcortical cysts 1
chr6_-_127620296 37.46 ENSRNOT00000012577
serpin family A member 1
chr2_-_180914940 37.38 ENSRNOT00000015732
tryptophan 2,3-dioxygenase
chr16_+_18690649 37.14 ENSRNOT00000015190
methionine adenosyltransferase 1A
chrX_+_143097525 35.55 ENSRNOT00000004559
coagulation factor IX
chr7_-_27552078 35.23 ENSRNOT00000059538
stabilin 2
chr5_+_124300477 34.46 ENSRNOT00000010100
complement C8 beta chain
chr5_-_124403195 33.94 ENSRNOT00000067850
complement C8 alpha chain
chr17_-_69404323 33.86 ENSRNOT00000051342
ENSRNOT00000066282
aldo-keto reductase family 1, member C2
chr5_+_134492756 33.83 ENSRNOT00000012888
ENSRNOT00000057095
ENSRNOT00000051385
cytochrome P450, family 4, subfamily a, polypeptide 1
chr14_+_22724399 32.78 ENSRNOT00000002724
UDP glucuronosyltransferase 2 family, polypeptide B10
chr6_+_128050250 32.02 ENSRNOT00000077517
ENSRNOT00000013961
Ab1-233
chr14_+_22553650 31.51 ENSRNOT00000092201
ENSRNOT00000002712
UDP glucuronosyltransferase 2 family, polypeptide B35
chr1_-_258877045 31.36 ENSRNOT00000071633
cytochrome P450, family 2, subfamily c, polypeptide 13
chr4_-_123557501 30.99 ENSRNOT00000075042
ENSRNOT00000085966
aldehyde dehydrogenase 1 family, member L1
chr8_-_50526843 29.95 ENSRNOT00000092188

chr2_+_55775274 29.73 ENSRNOT00000018545
complement C9
chr7_+_34326087 29.66 ENSRNOT00000006971
histidine ammonia lyase
chr9_+_100281339 29.33 ENSRNOT00000029127
alanine-glyoxylate aminotransferase
chr15_+_57290849 29.16 ENSRNOT00000014909
carboxypeptidase B2
chr17_-_43584152 29.14 ENSRNOT00000023241
solute carrier family 17, member 2
chr9_-_4978892 28.38 ENSRNOT00000015189
sulfotransferase family 1C member 3
chr9_+_6970507 28.27 ENSRNOT00000079488
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
chr2_+_114413410 26.99 ENSRNOT00000015866
solute carrier family 2 member 2
chr8_-_50539331 26.67 ENSRNOT00000088997

chr2_+_20857202 26.57 ENSRNOT00000078919
acyl-CoA thioesterase 12
chr13_+_51534025 26.14 ENSRNOT00000006637
synaptotagmin 2
chr1_+_213577122 25.40 ENSRNOT00000071925
similar to transthyretin (4L369)
chr3_+_56861396 25.36 ENSRNOT00000000008
ENSRNOT00000084375
glutamate decarboxylase 1
chr10_+_66942398 25.33 ENSRNOT00000018986
RAB11 family interacting protein 4
chr1_+_189364288 25.27 ENSRNOT00000080338
acyl-CoA synthetase medium-chain family member 1
chr1_-_221431713 25.07 ENSRNOT00000028485
transmembrane 7 superfamily member 2
chr10_+_65767930 25.03 ENSRNOT00000039954
vitronectin
chr12_-_19114399 24.83 ENSRNOT00000073099
cytochrome P450, family 3, subfamily a, polypeptide 9
chr1_-_258766881 24.74 ENSRNOT00000015801
cytochrome P450, family 2, subfamily c, polypeptide 12
chr5_-_77433847 24.71 ENSRNOT00000076906
ENSRNOT00000043056
similar to alpha-2u globulin PGCL2
major urinary protein 4
chr11_+_74057361 23.79 ENSRNOT00000048746
carboxypeptidase N subunit 2
chr10_-_71491743 22.86 ENSRNOT00000038955
uncharacterized LOC102552988
chr11_+_7422272 22.48 ENSRNOT00000075964
1,4-alpha-glucan branching enzyme 1
chr5_-_173233188 22.46 ENSRNOT00000055343
transmembrane protein 88B
chr4_+_153921900 22.13 ENSRNOT00000089482
solute carrier family 6 member 12
chr10_-_103340922 21.83 ENSRNOT00000004191
BTB domain containing 17
chr4_-_62840357 21.82 ENSRNOT00000059892
solute carrier family 13 member 4
chr11_-_60882379 21.63 ENSRNOT00000002799
CD200 receptor 1
chr6_+_132242328 21.20 ENSRNOT00000081088
cytochrome P450, family 46, subfamily a, polypeptide 1
chr5_+_142875773 21.20 ENSRNOT00000082120
ENSRNOT00000056496
EPH receptor A10
chr9_-_19880346 21.17 ENSRNOT00000014051
cytochrome P450, family 39, subfamily a, polypeptide 1
chr6_+_111176798 21.14 ENSRNOT00000072215
glutathione S-transferase zeta 1
chr5_-_140657745 20.95 ENSRNOT00000019080
major facilitator superfamily domain containing 2A
chr17_+_31441630 20.90 ENSRNOT00000083705
ENSRNOT00000023582
tubulin, beta 2B class IIb
chr3_-_127500709 20.83 ENSRNOT00000006330
hydroxyacid oxidase 1
chr5_-_4975436 20.83 ENSRNOT00000062006
XK related 9
chr5_-_77903062 20.73 ENSRNOT00000073954
ENSRNOT00000059320
ENSRNOT00000089382
ENSRNOT00000076074
ENSRNOT00000074349
major urinary protein-like
alpha2u globulin (LOC298111), mRNA
chr4_+_109497962 20.69 ENSRNOT00000057869
regenerating family member 1 alpha
chr8_-_46537050 19.87 ENSRNOT00000011284
sterol-C5-desaturase
chr4_+_57952982 19.80 ENSRNOT00000014465
carboxypeptidase A1
chr14_+_22251499 19.31 ENSRNOT00000087991
ENSRNOT00000002705
UDP glucuronosyltransferase 2 family, polypeptide A1
chr3_-_7141522 18.80 ENSRNOT00000014572
carboxyl ester lipase
chr2_+_150146234 18.70 ENSRNOT00000018761
arylacetamide deacetylase
chr1_+_100393303 18.62 ENSRNOT00000026251
synaptotagmin 3
chr4_-_77489535 18.33 ENSRNOT00000008728
protein disulfide isomerase family A, member 4
chr2_+_235264219 18.21 ENSRNOT00000086245
complement factor I
chr17_-_69827112 18.17 ENSRNOT00000023835
aldo-keto reductase family 1, member C14
chr1_-_85220237 17.75 ENSRNOT00000026907
syncollin
chr2_-_53140637 17.68 ENSRNOT00000060492
coiled-coil domain containing 152
chr4_+_175729726 17.55 ENSRNOT00000013230
solute carrier organic anion transporter family, member 1c1
chr5_-_77342299 17.29 ENSRNOT00000075994
similar to alpha-2u-globulin
chr4_+_153921115 17.23 ENSRNOT00000018821
solute carrier family 6 member 12
chr3_+_117416345 16.98 ENSRNOT00000056054
cortexin 2
chr11_-_64421248 16.77 ENSRNOT00000066997
immunoglobulin superfamily, member 11
chr7_-_106753592 16.71 ENSRNOT00000006930
potassium voltage-gated channel subfamily Q member 3
chr9_+_95256627 16.46 ENSRNOT00000025291
UDP glucuronosyltransferase family 1 member A5
chr3_+_134440195 16.43 ENSRNOT00000072928

chrX_+_118084890 16.12 ENSRNOT00000065293
5-hydroxytryptamine receptor 2C
chr5_+_124476168 15.96 ENSRNOT00000077754
similar to novel protein
chr15_+_42659371 15.83 ENSRNOT00000091612
clusterin
chr14_+_2050483 15.56 ENSRNOT00000000047
solute carrier family 26 member 1
chr7_-_12246729 15.49 ENSRNOT00000044030
receptor accessory protein 6
chr4_+_84423653 15.32 ENSRNOT00000012655
chimerin 2
chr9_+_95285592 15.23 ENSRNOT00000063853
UDP glucuronosyltransferase family 1 member A5
chr10_+_59765258 15.17 ENSRNOT00000026351
sedoheptulokinase
chr16_+_3293599 14.81 ENSRNOT00000081999
ENSRNOT00000047118
ENSRNOT00000020427
ELKS/RAB6-interacting/CAST family member 2
chr10_-_83898527 14.77 ENSRNOT00000009815
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr3_+_154395187 14.72 ENSRNOT00000050810
V-set and transmembrane domain containing 2 like
chr5_-_58124681 14.67 ENSRNOT00000019795
sigma non-opioid intracellular receptor 1
chr8_+_52729003 14.62 ENSRNOT00000081738
neurexophilin and PC-esterase domain family, member 4
chr15_+_47455690 14.30 ENSRNOT00000075276
serine protease 55-like
chr9_-_98551410 14.28 ENSRNOT00000066346
ENSRNOT00000086678
hes family bHLH transcription factor 6
chr10_+_109708755 14.21 ENSRNOT00000083601
glucagon receptor
chr5_-_109651730 13.67 ENSRNOT00000093032
ELAV like RNA binding protein 2
chr10_+_37215937 13.63 ENSRNOT00000006567
secretion associated, Ras related GTPase 1B
chr13_-_72063347 13.10 ENSRNOT00000090544
ENSRNOT00000003869
calcium voltage-gated channel subunit alpha1 E
chr17_+_69588085 13.06 ENSRNOT00000064884
aldo-keto reductase family 1, member C12-like 1
chr5_-_77492013 13.04 ENSRNOT00000012293
alpha-2u globulin PGCL5
chr1_-_211520699 12.67 ENSRNOT00000009178
serine/threonine kinase 32C
chr12_-_52124779 12.40 ENSRNOT00000088839
polypeptide N-acetylgalactosaminyltransferase 9
chr9_+_4094995 12.32 ENSRNOT00000089450
sulfotransferase 1C2-like
chr1_-_174119815 12.30 ENSRNOT00000019368
tripartite motif-containing 66
chr15_-_14737704 12.15 ENSRNOT00000011307
synaptoporin
chr10_-_27366665 12.10 ENSRNOT00000004725
gamma-aminobutyric acid type A receptor alpha1 subunit
chr5_-_40237591 12.09 ENSRNOT00000011393
fucosyltransferase 9
chr1_-_220096319 12.02 ENSRNOT00000091787
ENSRNOT00000073983
copper chaperone for superoxide dismutase
chr9_+_101005082 11.95 ENSRNOT00000082949
neuraminidase 4
chr12_+_8725517 11.88 ENSRNOT00000001243
solute carrier family 46, member 3
chrM_+_7758 11.78 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr8_+_13796021 11.75 ENSRNOT00000013927
V-set and transmembrane domain containing 5
chr1_+_167937026 11.73 ENSRNOT00000020655
olfactory receptor 57
chr15_-_23969011 11.71 ENSRNOT00000014821
GTP cyclohydrolase 1
chr8_+_85259982 11.70 ENSRNOT00000010409
ELOVL fatty acid elongase 5
chr10_-_65820538 11.66 ENSRNOT00000011808
transmembrane protein 97
chr1_+_42170281 11.57 ENSRNOT00000092879
vasoactive intestinal peptide
chr2_-_188412329 11.49 ENSRNOT00000033917
ENSRNOT00000080185
farnesyl diphosphate synthase
chr1_+_102900286 11.45 ENSRNOT00000017468
lactate dehydrogenase A
chr5_+_78222504 11.36 ENSRNOT00000019544
solute carrier family 31 member 1
chr1_+_282134981 11.34 ENSRNOT00000036203
nanos C2HC-type zinc finger 1
chr4_+_151298548 11.24 ENSRNOT00000010746
calcium voltage-gated channel auxiliary subunit alpha2delta 4
chr1_-_5165859 11.18 ENSRNOT00000044325
ENSRNOT00000019319
glutamate metabotropic receptor 1
chr13_+_83681322 11.18 ENSRNOT00000004206
mitochondrial pyruvate carrier 2
chr10_-_107539465 11.08 ENSRNOT00000004524
RNA binding protein, fox-1 homolog 3
chr10_-_35833861 11.05 ENSRNOT00000049942
calnexin
chr3_+_114355798 10.98 ENSRNOT00000024658
ENSRNOT00000036435
solute carrier family 28 member 2
chr15_-_80713153 10.94 ENSRNOT00000063800
kelch-like family member 1
chr2_-_170460754 10.90 ENSRNOT00000013009
SLIT and NTRK-like family, member 3
chr13_-_36156076 10.89 ENSRNOT00000074685
diazepam binding inhibitor, acyl-CoA binding protein
chr2_+_243656579 10.78 ENSRNOT00000036993
alcohol dehydrogenase 1 (class I)
chr5_-_59553416 10.76 ENSRNOT00000090490
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr10_-_8654892 10.68 ENSRNOT00000066534
RNA binding protein, fox-1 homolog 1
chr17_+_69468427 10.63 ENSRNOT00000058413
similar to 20-alpha-hydroxysteroid dehydrogenase
chr13_-_50514151 10.56 ENSRNOT00000003951
renin
chr10_+_88997399 10.53 ENSRNOT00000027116
MLX, MAX dimerization protein
chr8_-_2045817 10.47 ENSRNOT00000009542
ENSRNOT00000081171
ENSRNOT00000078765
glutamate ionotropic receptor AMPA type subunit 4
chr2_-_235177275 10.44 ENSRNOT00000093153
uncharacterized LOC103691699
chr15_+_42640146 10.43 ENSRNOT00000078861
clusterin
chr17_+_69761118 10.35 ENSRNOT00000023739
aldo-keto reductase family 1, member C3
chr11_-_77593171 10.29 ENSRNOT00000002645
ENSRNOT00000043498
interleukin 1 receptor accessory protein
chr15_-_8914501 10.28 ENSRNOT00000008752
thyroid hormone receptor beta
chr2_+_22909569 10.26 ENSRNOT00000073871
homer scaffolding protein 1
chr4_-_121969446 10.16 ENSRNOT00000085001
vomeronasal 1 receptor 99
chr3_-_176816114 10.15 ENSRNOT00000079262
ENSRNOT00000018697
stathmin 3
chr9_+_95241609 10.12 ENSRNOT00000032634
ENSRNOT00000077416
UDP glucuronosyltransferase family 1 member A5
chr5_-_166133274 10.11 ENSRNOT00000078830
kinesin family member 1B
chr16_-_81756654 10.08 ENSRNOT00000026653
cullin 4A
chr10_+_1834518 10.06 ENSRNOT00000061709
predicted gene 1758
chr14_-_46529375 9.86 ENSRNOT00000077306
ENSRNOT00000078682
rRNA promoter binding protein
chr12_-_35979193 9.85 ENSRNOT00000071104
transmembrane protein 132B
chr4_+_21462779 9.74 ENSRNOT00000089747
glutamate metabotropic receptor 3
chr9_-_91882927 9.73 ENSRNOT00000084446
phosphotyrosine interaction domain containing 1
chr3_+_11593655 9.70 ENSRNOT00000074122
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr13_+_77485113 9.70 ENSRNOT00000080254
tenascin R
chr10_+_91187593 9.68 ENSRNOT00000004163
acyl-CoA binding domain containing 4
chr10_-_15465404 9.66 ENSRNOT00000077826
ENSRNOT00000027593
2,4-dienoyl-CoA reductase 2
chr20_+_41100071 9.59 ENSRNOT00000000658
TSPY-like 4
chr3_+_177310753 9.43 ENSRNOT00000031448
myelin transcription factor 1
chr2_+_209840404 9.39 ENSRNOT00000050149
potassium voltage-gated channel subfamily A member 2
chr2_-_2814690 9.33 ENSRNOT00000029265
G protein-coupled receptor 150
chr10_-_37215899 9.31 ENSRNOT00000006356
SEC24 homolog A, COPII coat complex component
chr1_-_264172729 9.25 ENSRNOT00000018447
stearoyl-CoA desaturase
chr10_-_96131880 9.09 ENSRNOT00000004578
calcium voltage-gated channel auxiliary subunit gamma 5
chrX_+_65800059 9.09 ENSRNOT00000076428
G protein-coupled receptor 165
chr1_-_128604188 9.05 ENSRNOT00000033858
leucine rich repeat containing 28
chr1_+_67025240 9.05 ENSRNOT00000051024
vomeronasal 1 receptor 47
chr1_-_82344345 9.04 ENSRNOT00000051892
ENSRNOT00000090629
ENSRNOT00000029487
ENSRNOT00000027933
carcinoembryonic antigen related cell adhesion molecule 1
chr13_-_44345735 9.04 ENSRNOT00000005006
transmembrane protein 163
chr17_+_81455955 8.98 ENSRNOT00000044313
solute carrier family 39 member 12
chr10_-_107539658 8.97 ENSRNOT00000089346
RNA binding protein, fox-1 homolog 3
chr16_-_10603850 8.96 ENSRNOT00000087737
family with sequence similarity 35, member A
chr13_-_39643361 8.92 ENSRNOT00000003527
dipeptidylpeptidase 10
chr5_+_135029955 8.91 ENSRNOT00000074860
uncharacterized LOC100911669
chr6_+_97168453 8.90 ENSRNOT00000085790
synaptotagmin 16
chr18_+_62805410 8.88 ENSRNOT00000086679
G protein subunit alpha L
chr13_-_51076852 8.80 ENSRNOT00000078993
adenosine A1 receptor
chrX_+_28072826 8.79 ENSRNOT00000039796
FERM and PDZ domain containing 4
chr12_+_11814071 8.70 ENSRNOT00000039149
transmembrane protein 130
chr6_-_115616766 8.66 ENSRNOT00000006143
ENSRNOT00000045870
SEL1L ERAD E3 ligase adaptor subunit
chr2_+_228544418 8.64 ENSRNOT00000013030
translocation associated membrane protein 1-like 1
chrX_-_15707436 8.62 ENSRNOT00000085907
synaptophysin
chr9_+_73528681 8.47 ENSRNOT00000084340
unc-80 homolog, NALCN activator
chr4_+_22859622 8.46 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr1_-_213635546 8.45 ENSRNOT00000018861
sirtuin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Cux1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
36.4 109.2 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) activation of plasma proteins involved in acute inflammatory response(GO:0002541)
18.3 127.9 GO:0009804 coumarin metabolic process(GO:0009804)
17.8 53.5 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
17.2 51.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
14.8 44.5 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
14.7 44.2 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
13.4 40.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
12.5 37.5 GO:0033986 response to methanol(GO:0033986)
10.3 31.0 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
10.3 41.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
9.9 29.7 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
9.8 39.4 GO:0009992 cellular water homeostasis(GO:0009992)
9.8 29.3 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) oxalic acid secretion(GO:0046724)
9.7 29.2 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
8.8 26.3 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
8.5 33.8 GO:0048252 lauric acid metabolic process(GO:0048252)
8.3 24.8 GO:0009822 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
8.0 8.0 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
7.2 35.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
7.0 21.0 GO:0051977 lysophospholipid transport(GO:0051977)
6.9 20.7 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
6.7 133.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
6.4 64.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
6.4 70.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
6.2 37.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
5.8 57.9 GO:0018298 protein-chromophore linkage(GO:0018298)
5.7 28.3 GO:0015755 fructose transport(GO:0015755)
5.4 16.1 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
5.3 15.9 GO:1901143 insulin catabolic process(GO:1901143)
5.2 20.8 GO:0009441 glycolate metabolic process(GO:0009441)
5.1 25.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
4.9 64.3 GO:0052695 cellular glucuronidation(GO:0052695)
4.6 18.3 GO:1903334 positive regulation of protein folding(GO:1903334)
4.5 50.0 GO:0051132 NK T cell activation(GO:0051132)
4.4 61.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
3.9 11.7 GO:0014916 regulation of lung blood pressure(GO:0014916)
3.7 11.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
3.6 10.8 GO:0006117 acetaldehyde metabolic process(GO:0006117)
3.6 10.8 GO:0046380 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
3.5 21.1 GO:0006572 tyrosine catabolic process(GO:0006572)
3.4 10.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
3.3 3.3 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518)
3.2 37.8 GO:0047484 regulation of response to osmotic stress(GO:0047484)
3.1 9.3 GO:1903699 tarsal gland development(GO:1903699)
2.9 8.8 GO:0032900 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) negative regulation of long term synaptic depression(GO:1900453)
2.9 8.6 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
2.8 11.4 GO:0098705 copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
2.8 14.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
2.8 8.3 GO:0033693 neurofilament bundle assembly(GO:0033693)
2.7 10.9 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
2.6 10.6 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
2.6 7.8 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
2.5 25.3 GO:0070314 G1 to G0 transition(GO:0070314)
2.5 47.2 GO:0042359 vitamin D metabolic process(GO:0042359)
2.5 7.4 GO:0098749 cerebellar neuron development(GO:0098749)
2.4 14.7 GO:0038003 opioid receptor signaling pathway(GO:0038003)
2.4 7.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
2.4 9.7 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
2.3 11.7 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.3 18.7 GO:0070459 prolactin secretion(GO:0070459)
2.3 2.3 GO:0090032 negative regulation of steroid hormone biosynthetic process(GO:0090032)
2.3 38.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
2.3 24.8 GO:0070327 thyroid hormone transport(GO:0070327)
2.3 13.5 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
2.2 15.6 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
2.2 6.5 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
2.0 10.1 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
2.0 6.0 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
2.0 10.0 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384)
2.0 6.0 GO:0010034 response to acetate(GO:0010034)
2.0 6.0 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
1.9 34.4 GO:0097503 sialylation(GO:0097503)
1.9 5.7 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
1.9 11.4 GO:0006113 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
1.9 5.7 GO:0030091 protein repair(GO:0030091)
1.9 3.8 GO:1905232 cellular response to L-glutamate(GO:1905232)
1.9 5.7 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
1.9 18.7 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
1.8 12.5 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
1.8 3.5 GO:0006553 lysine metabolic process(GO:0006553)
1.7 8.7 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
1.7 10.3 GO:0008050 female courtship behavior(GO:0008050)
1.7 8.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.6 6.6 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
1.6 8.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
1.6 13.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
1.6 9.8 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
1.6 9.7 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
1.6 8.0 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
1.6 49.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
1.6 4.7 GO:0002086 diaphragm contraction(GO:0002086)
1.6 9.4 GO:0021633 optic nerve structural organization(GO:0021633)
1.6 39.0 GO:0008211 glucocorticoid metabolic process(GO:0008211)
1.6 9.3 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
1.5 3.0 GO:0097187 dentinogenesis(GO:0097187)
1.5 8.7 GO:0051182 coenzyme transport(GO:0051182)
1.4 4.3 GO:0016267 O-glycan processing, core 1(GO:0016267)
1.4 55.5 GO:0006956 complement activation(GO:0006956)
1.4 6.9 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
1.4 5.5 GO:0014028 notochord formation(GO:0014028)
1.4 6.8 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
1.3 6.7 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
1.3 3.9 GO:0001966 thigmotaxis(GO:0001966)
1.3 14.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
1.3 3.8 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
1.3 8.9 GO:0009405 pathogenesis(GO:0009405)
1.3 3.8 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)
1.3 3.8 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
1.2 2.5 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
1.2 6.1 GO:0002317 plasma cell differentiation(GO:0002317)
1.2 4.9 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.2 29.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
1.2 15.6 GO:0019532 oxalate transport(GO:0019532)
1.2 4.7 GO:0006285 base-excision repair, AP site formation(GO:0006285)
1.2 8.2 GO:0042420 dopamine catabolic process(GO:0042420)
1.2 8.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.2 2.3 GO:0006004 fucose metabolic process(GO:0006004)
1.1 21.8 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
1.1 7.7 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
1.1 29.0 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
1.1 3.2 GO:0035928 rRNA import into mitochondrion(GO:0035928)
1.1 9.5 GO:0006689 ganglioside catabolic process(GO:0006689)
1.0 7.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
1.0 9.4 GO:0060539 diaphragm development(GO:0060539)
1.0 8.4 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.0 3.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
1.0 5.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
1.0 5.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.0 12.1 GO:0071420 cellular response to histamine(GO:0071420)
1.0 3.9 GO:0018963 phthalate metabolic process(GO:0018963)
1.0 2.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.0 44.6 GO:0016126 sterol biosynthetic process(GO:0016126)
1.0 9.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.9 3.8 GO:0071283 cellular response to iron(III) ion(GO:0071283)
0.9 2.8 GO:0045054 constitutive secretory pathway(GO:0045054)
0.9 4.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.9 3.7 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.9 2.8 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.9 5.5 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.9 2.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.9 2.7 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.9 5.4 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.9 3.6 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.9 9.8 GO:0035095 behavioral response to nicotine(GO:0035095)
0.9 4.4 GO:0035627 ceramide transport(GO:0035627)
0.9 3.5 GO:0006824 cobalt ion transport(GO:0006824)
0.9 25.4 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.9 8.7 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.9 12.1 GO:0036065 fucosylation(GO:0036065)
0.9 1.7 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.8 8.5 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.8 0.8 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.8 9.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.8 2.4 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.8 6.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.8 45.8 GO:0007566 embryo implantation(GO:0007566)
0.8 2.4 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.8 6.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.8 13.8 GO:0001675 acrosome assembly(GO:0001675)
0.8 16.7 GO:0061548 ganglion development(GO:0061548)
0.7 6.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.7 3.7 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.7 6.6 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.7 7.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.7 5.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.7 3.5 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.7 2.1 GO:2000853 negative regulation of corticosterone secretion(GO:2000853)
0.7 8.0 GO:0007340 acrosome reaction(GO:0007340)
0.6 3.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.6 17.8 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.6 1.8 GO:0060125 pancreatic amylase secretion(GO:0036395) negative regulation of growth hormone secretion(GO:0060125) regulation of pancreatic amylase secretion(GO:1902276)
0.6 7.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.6 5.4 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.6 1.8 GO:0090648 response to environmental enrichment(GO:0090648)
0.6 10.7 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.6 5.3 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.6 2.9 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.6 6.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.6 2.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.6 17.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.6 3.3 GO:0071569 protein ufmylation(GO:0071569)
0.6 2.8 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.5 10.4 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.5 9.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.5 4.8 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.5 1.6 GO:0016240 autophagosome docking(GO:0016240)
0.5 1.6 GO:2000464 positive regulation of astrocyte chemotaxis(GO:2000464)
0.5 8.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.5 4.5 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.5 2.0 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.5 1.5 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.5 2.4 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.5 1.5 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.5 3.9 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.5 12.0 GO:0019430 removal of superoxide radicals(GO:0019430)
0.5 6.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.5 1.4 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.5 3.7 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.5 3.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.4 2.2 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.4 0.9 GO:1904954 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.4 2.6 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.4 11.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 6.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.4 2.9 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.4 35.2 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.4 16.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 4.8 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.4 2.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.4 1.9 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) spermine catabolic process(GO:0046208)
0.4 5.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.4 1.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.4 17.1 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.4 3.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.4 6.5 GO:0006020 inositol metabolic process(GO:0006020)
0.4 2.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.4 1.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 8.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.3 4.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.3 4.5 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 4.8 GO:0048240 sperm capacitation(GO:0048240)
0.3 65.7 GO:0006790 sulfur compound metabolic process(GO:0006790)
0.3 9.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.3 5.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.3 13.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.3 0.3 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.3 28.5 GO:0007596 blood coagulation(GO:0007596)
0.3 0.9 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.3 9.8 GO:0009303 rRNA transcription(GO:0009303)
0.3 3.1 GO:0070995 NADPH oxidation(GO:0070995)
0.3 11.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.3 1.2 GO:0015879 carnitine transport(GO:0015879)
0.3 1.2 GO:0002188 translation reinitiation(GO:0002188)
0.3 2.6 GO:0050957 equilibrioception(GO:0050957)
0.3 1.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.3 5.3 GO:0050951 sensory perception of temperature stimulus(GO:0050951)
0.3 3.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 1.9 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.3 1.6 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.3 1.3 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.3 5.2 GO:0032098 regulation of appetite(GO:0032098)
0.3 4.4 GO:0043248 proteasome assembly(GO:0043248)
0.3 1.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.3 1.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.3 5.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.3 3.5 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.2 1.2 GO:0007000 nucleolus organization(GO:0007000)
0.2 3.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.2 3.6 GO:0031167 rRNA methylation(GO:0031167)
0.2 3.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 3.0 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 4.1 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.2 2.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 1.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 2.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 5.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 3.4 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.2 6.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 254.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 0.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 0.9 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 0.6 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.2 9.4 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.2 12.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 1.6 GO:0051597 response to methylmercury(GO:0051597)
0.2 6.2 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 4.8 GO:0007628 adult walking behavior(GO:0007628)
0.2 9.0 GO:0017158 regulation of calcium ion-dependent exocytosis(GO:0017158)
0.2 5.2 GO:0018345 protein palmitoylation(GO:0018345)
0.2 2.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.2 1.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 4.7 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 0.8 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.2 4.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.2 3.9 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.1 2.2 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 1.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.4 GO:0032197 transposition, RNA-mediated(GO:0032197)
0.1 0.6 GO:0090181 regulation of cholesterol metabolic process(GO:0090181)
0.1 1.6 GO:0044804 nucleophagy(GO:0044804)
0.1 1.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.1 GO:0048820 hair follicle maturation(GO:0048820)
0.1 0.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 2.4 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 1.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.8 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 7.5 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.1 0.5 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 4.8 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 1.0 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.4 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 1.3 GO:0015671 gas transport(GO:0015669) oxygen transport(GO:0015671)
0.1 1.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 1.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.7 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.1 0.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.7 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.9 GO:0042407 cristae formation(GO:0042407)
0.1 3.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 6.0 GO:0030901 midbrain development(GO:0030901)
0.1 0.3 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.1 2.4 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.5 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.1 1.3 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.4 GO:0007097 nuclear migration(GO:0007097)
0.1 0.2 GO:2000292 regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.1 0.9 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 0.9 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 1.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 1.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 2.4 GO:0051289 protein homotetramerization(GO:0051289)
0.0 1.6 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.3 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.4 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.0 1.4 GO:0001942 hair follicle development(GO:0001942)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 1.3 GO:0007601 visual perception(GO:0007601)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.1 GO:0048671 negative regulation of collateral sprouting(GO:0048671)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
14.0 98.1 GO:0005579 membrane attack complex(GO:0005579)
11.7 70.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
5.2 15.5 GO:0044317 rod spherule(GO:0044317)
4.8 52.4 GO:0042583 chromaffin granule(GO:0042583)
2.9 8.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
2.8 17.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
2.8 11.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
2.8 8.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
2.4 7.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
2.4 47.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
2.3 6.9 GO:0060187 cell pole(GO:0060187)
2.2 6.5 GO:0071942 XPC complex(GO:0071942)
2.1 44.5 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
2.1 27.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.9 9.7 GO:0072534 perineuronal net(GO:0072534)
1.7 18.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.6 6.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
1.5 7.7 GO:1990769 proximal neuron projection(GO:1990769)
1.4 29.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.2 4.8 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
1.2 7.0 GO:0002142 stereocilia ankle link complex(GO:0002142)
1.1 11.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.1 10.0 GO:0071821 FANCM-MHF complex(GO:0071821)
1.1 11.0 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
1.1 10.7 GO:0030891 VCB complex(GO:0030891)
1.1 18.2 GO:0032279 asymmetric synapse(GO:0032279)
1.0 5.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
1.0 124.2 GO:0072562 blood microparticle(GO:0072562)
0.9 26.1 GO:0042588 zymogen granule(GO:0042588)
0.9 3.5 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.8 2.5 GO:0034457 Mpp10 complex(GO:0034457)
0.8 4.8 GO:0036128 CatSper complex(GO:0036128)
0.8 40.3 GO:0048786 presynaptic active zone(GO:0048786)
0.7 113.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.7 19.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.7 2.8 GO:0035339 SPOTS complex(GO:0035339)
0.7 8.2 GO:0016600 flotillin complex(GO:0016600)
0.7 11.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.7 15.7 GO:0043194 axon initial segment(GO:0043194)
0.6 1.2 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.6 28.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.6 12.1 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.6 36.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.6 9.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.5 9.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.5 6.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.5 20.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.5 7.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.5 3.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.5 9.7 GO:0097449 astrocyte projection(GO:0097449)
0.5 1.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.5 7.0 GO:0043196 varicosity(GO:0043196)
0.5 2.5 GO:0002081 outer acrosomal membrane(GO:0002081)
0.5 361.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.5 9.0 GO:0031528 microvillus membrane(GO:0031528)
0.4 1.8 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.4 2.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.4 12.6 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.4 3.2 GO:0000815 ESCRT III complex(GO:0000815)
0.4 1.6 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.4 9.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 3.9 GO:0071439 clathrin complex(GO:0071439)
0.3 27.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.3 1.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.3 2.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 4.6 GO:0030057 desmosome(GO:0030057)
0.3 18.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 6.5 GO:0033391 chromatoid body(GO:0033391)
0.3 28.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.3 1.3 GO:0097422 tubular endosome(GO:0097422)
0.3 2.7 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 34.0 GO:0016363 nuclear matrix(GO:0016363)
0.3 1.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 10.8 GO:0043034 costamere(GO:0043034)
0.3 1.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 18.9 GO:0031526 brush border membrane(GO:0031526)
0.3 80.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 3.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 2.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 6.7 GO:0060170 ciliary membrane(GO:0060170)
0.2 2.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 2.8 GO:0030666 endocytic vesicle membrane(GO:0030666) phagocytic vesicle membrane(GO:0030670)
0.2 8.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 0.5 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.2 9.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 6.0 GO:0005771 multivesicular body(GO:0005771)
0.2 2.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 3.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 292.6 GO:0005615 extracellular space(GO:0005615)
0.2 0.6 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 1.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 6.1 GO:0031902 late endosome membrane(GO:0031902)
0.1 1.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 2.8 GO:0010369 chromocenter(GO:0010369)
0.1 12.2 GO:0055037 recycling endosome(GO:0055037)
0.1 7.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 3.6 GO:0035861 site of double-strand break(GO:0035861)
0.1 9.8 GO:0043204 perikaryon(GO:0043204)
0.1 0.5 GO:0032044 DSIF complex(GO:0032044)
0.1 2.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 10.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.7 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 5.9 GO:0045095 keratin filament(GO:0045095)
0.1 1.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 5.8 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.9 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 3.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 1.0 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 58.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 72.7 GO:0005739 mitochondrion(GO:0005739)
0.1 7.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 13.4 GO:0030424 axon(GO:0030424)
0.1 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 184.5 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
20.0 79.8 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
15.6 62.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
12.5 37.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
12.4 37.1 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
11.7 11.7 GO:0019238 cyclohydrolase activity(GO:0019238)
11.4 57.2 GO:0019862 IgA binding(GO:0019862)
10.8 53.8 GO:0005534 galactose binding(GO:0005534)
10.3 51.6 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
10.2 335.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391)
9.8 49.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
9.3 56.0 GO:0005499 vitamin D binding(GO:0005499)
8.4 42.0 GO:0005550 pheromone binding(GO:0005550)
8.3 33.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
7.5 22.5 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
7.1 28.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
7.1 21.2 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
6.6 26.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
6.6 39.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
6.3 18.8 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
6.2 192.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
5.9 29.7 GO:0016841 ammonia-lyase activity(GO:0016841)
5.9 29.3 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
5.4 16.1 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
5.2 20.8 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973)
5.1 15.3 GO:0001565 phorbol ester receptor activity(GO:0001565)
5.1 25.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
4.4 31.0 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
4.2 29.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
3.6 10.9 GO:0030156 benzodiazepine receptor binding(GO:0030156)
3.6 25.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
3.6 10.8 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
3.6 17.8 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
3.6 14.2 GO:0004967 glucagon receptor activity(GO:0004967)
3.5 10.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
3.5 52.1 GO:0005542 folic acid binding(GO:0005542)
3.4 10.3 GO:0002114 interleukin-33 receptor activity(GO:0002114)
3.2 9.7 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
3.2 16.1 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
3.2 35.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
3.2 25.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
3.1 24.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
3.0 27.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
3.0 14.9 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
2.9 11.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
2.8 67.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
2.7 11.0 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
2.7 35.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
2.6 13.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
2.6 15.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
2.4 14.7 GO:0004985 opioid receptor activity(GO:0004985)
2.4 29.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
2.4 12.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
2.4 40.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
2.3 11.3 GO:0051185 coenzyme transporter activity(GO:0051185)
2.2 11.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
2.2 39.5 GO:0001848 complement binding(GO:0001848)
2.1 8.6 GO:0010465 nerve growth factor receptor activity(GO:0010465)
2.0 12.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
2.0 10.0 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
2.0 6.0 GO:0008384 IkappaB kinase activity(GO:0008384)
1.9 5.7 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
1.9 15.0 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
1.8 7.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
1.8 9.0 GO:0046790 virion binding(GO:0046790)
1.8 10.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.7 21.0 GO:0015245 fatty acid transporter activity(GO:0015245)
1.7 45.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.7 10.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.6 8.2 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
1.6 26.3 GO:0051787 misfolded protein binding(GO:0051787)
1.6 6.5 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829)
1.6 8.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.6 4.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
1.6 4.7 GO:0042296 ISG15 transferase activity(GO:0042296)
1.5 6.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
1.5 21.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
1.5 6.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
1.5 8.9 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
1.5 4.4 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.4 5.7 GO:0005136 interleukin-4 receptor binding(GO:0005136)
1.4 5.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.4 11.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
1.4 4.3 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
1.4 11.2 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
1.4 6.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
1.4 6.8 GO:0043559 insulin binding(GO:0043559)
1.4 29.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
1.3 6.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.2 20.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
1.2 4.8 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
1.2 3.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.2 4.8 GO:0030350 iron-responsive element binding(GO:0030350)
1.1 16.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.1 4.4 GO:0017089 glycolipid transporter activity(GO:0017089)
1.0 3.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
1.0 3.8 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.9 10.3 GO:0070324 thyroid hormone receptor activity(GO:0004887) thyroid hormone binding(GO:0070324)
0.9 3.7 GO:0050682 AF-2 domain binding(GO:0050682)
0.9 2.7 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.9 3.6 GO:0055100 adiponectin binding(GO:0055100)
0.9 8.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.9 14.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.9 8.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.9 18.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.8 6.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.8 197.2 GO:0017171 serine hydrolase activity(GO:0017171)
0.8 4.1 GO:1990254 keratin filament binding(GO:1990254)
0.8 27.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.8 3.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.8 7.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.8 8.0 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.8 4.7 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.8 7.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.8 3.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.8 8.4 GO:0005000 vasopressin receptor activity(GO:0005000)
0.8 3.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.7 11.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.7 14.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.7 3.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.7 8.5 GO:0070403 NAD+ binding(GO:0070403)
0.7 31.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.7 9.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.6 1.9 GO:0019809 spermidine binding(GO:0019809)
0.6 2.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.6 5.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.6 54.9 GO:0005496 steroid binding(GO:0005496)
0.6 21.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.6 2.5 GO:0032190 acrosin binding(GO:0032190)
0.6 9.8 GO:0042166 acetylcholine binding(GO:0042166)
0.6 4.0 GO:0004064 arylesterase activity(GO:0004064)
0.6 5.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.5 14.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 7.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.5 1.6 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.5 3.6 GO:0031433 telethonin binding(GO:0031433)
0.5 1.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.5 2.5 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.5 5.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.5 2.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5 1.4 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.5 9.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.5 3.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.5 5.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.4 1.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.4 3.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.4 20.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.4 9.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 2.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.4 8.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.4 1.2 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.4 3.4 GO:0016805 dipeptidase activity(GO:0016805)
0.4 8.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.4 8.3 GO:0043274 phospholipase binding(GO:0043274)
0.3 3.5 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 1.0 GO:0034618 arginine binding(GO:0034618)
0.3 3.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 2.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.3 13.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.3 1.6 GO:0005131 growth hormone receptor binding(GO:0005131)
0.3 2.2 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 6.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 1.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.3 1.1 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.3 3.2 GO:0008097 5S rRNA binding(GO:0008097)
0.3 1.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 2.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.3 1.0 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.2 14.8 GO:0051087 chaperone binding(GO:0051087)
0.2 4.5 GO:0008199 ferric iron binding(GO:0008199)
0.2 4.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 4.9 GO:0008483 transaminase activity(GO:0008483)
0.2 3.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 2.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.2 1.3 GO:0034452 dynactin binding(GO:0034452)
0.2 0.8 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 4.8 GO:0031489 myosin V binding(GO:0031489)
0.2 3.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.2 4.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 8.2 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.2 255.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 5.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.9 GO:0001729 ceramide kinase activity(GO:0001729)
0.2 16.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 21.3 GO:0001948 glycoprotein binding(GO:0001948)
0.2 8.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 0.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 16.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 4.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 5.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 16.4 GO:0008565 protein transporter activity(GO:0008565)
0.2 3.4 GO:0005504 fatty acid binding(GO:0005504)
0.1 3.1 GO:0008198 ferrous iron binding(GO:0008198)
0.1 1.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 6.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 18.7 GO:0005179 hormone activity(GO:0005179)
0.1 1.7 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 3.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 3.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 4.8 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 3.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 2.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 2.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 4.4 GO:0051018 protein kinase A binding(GO:0051018)
0.1 7.7 GO:0008083 growth factor activity(GO:0008083)
0.1 0.4 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 0.9 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.3 GO:0036374 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 2.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.3 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 2.6 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.6 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0070001 aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 70.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.9 20.7 ST JAK STAT PATHWAY Jak-STAT Pathway
1.4 343.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.8 15.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.7 37.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.6 10.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.6 27.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 4.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.5 5.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.4 7.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 8.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 7.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3 49.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 14.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 10.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.3 14.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 13.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 10.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 9.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 15.9 PID P73PATHWAY p73 transcription factor network
0.2 5.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 12.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 4.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2 10.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 2.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 1.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 7.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 3.5 PID ATM PATHWAY ATM pathway
0.1 2.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 148.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
5.1 97.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
4.6 97.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
4.6 160.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
4.2 37.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
2.5 66.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
2.5 32.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
2.1 49.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.8 17.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
1.6 53.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
1.6 27.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.5 21.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
1.5 8.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
1.5 11.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.5 26.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.4 24.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.4 6.8 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.3 8.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
1.3 22.8 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.2 35.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
1.0 11.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.0 20.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.9 151.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.9 12.2 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.8 9.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.8 71.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.8 32.9 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.7 57.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.7 12.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.7 10.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.7 12.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.7 6.0 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.6 14.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.6 11.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.5 10.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.5 8.8 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.5 26.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.5 6.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.5 14.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.5 25.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.4 8.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.4 8.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.4 6.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.4 6.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 1.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.4 26.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 3.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 6.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.3 6.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.3 12.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.3 5.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 3.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.3 6.6 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.2 4.0 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 2.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 6.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 5.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 6.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 3.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 4.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 5.5 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.2 10.7 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 3.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 5.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 3.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 4.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 2.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.0 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 4.2 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 2.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.0 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis