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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Ctcfl_Ctcf

Z-value: 1.15

Motif logo

Transcription factors associated with Ctcfl_Ctcf

Gene Symbol Gene ID Gene Info
ENSRNOG00000028661 CCCTC-binding factor like
ENSRNOG00000017674 CCCTC-binding factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ctcfrn6_v1_chr19_+_37600148_376001480.164.2e-03Click!
Ctcflrn6_v1_chr3_-_171166454_171166454-0.132.2e-02Click!

Activity profile of Ctcfl_Ctcf motif

Sorted Z-values of Ctcfl_Ctcf motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_41482728 73.62 ENSRNOT00000022943
calbindin 2
chr3_-_11382004 59.90 ENSRNOT00000047921
ENSRNOT00000064039
dynamin 1
chr3_-_52510507 57.80 ENSRNOT00000091259
sodium voltage-gated channel alpha subunit 1
chr14_+_83752393 57.32 ENSRNOT00000081123
selenoprotein M
chr3_+_51687809 55.89 ENSRNOT00000087242
sodium voltage-gated channel alpha subunit 2
chr9_-_32019205 44.96 ENSRNOT00000016194
adhesion G protein-coupled receptor B3
chr3_-_51643140 44.85 ENSRNOT00000006646
sodium voltage-gated channel alpha subunit 3
chr1_-_89483988 44.55 ENSRNOT00000028603
FXYD domain-containing ion transport regulator 7
chr11_+_36851038 43.86 ENSRNOT00000002221
ENSRNOT00000061047
Purkinje cell protein 4
chr18_+_30004565 43.57 ENSRNOT00000027393
protocadherin alpha 4
chr6_+_137997335 42.86 ENSRNOT00000006872
transmembrane protein 121
chr18_+_29951094 42.14 ENSRNOT00000027402
protocadherin alpha-1-like
chr18_+_30509393 36.58 ENSRNOT00000043846
protocadherin beta 12
chr12_-_41448668 36.02 ENSRNOT00000001856
RAS protein activator like 1 (GAP1 like)
chr18_+_30023828 35.52 ENSRNOT00000079008
protocadherin alpha 4
chr18_+_30474947 34.96 ENSRNOT00000027188
protocadherin beta 9
chr8_-_117237229 33.96 ENSRNOT00000071381
kelch domain containing 8B
chr18_+_29972808 33.87 ENSRNOT00000074051
protocadherin alpha 4
chr1_+_241594565 33.40 ENSRNOT00000020123
amyloid beta precursor protein binding family A member 1
chr10_-_90393317 32.22 ENSRNOT00000028563
family with sequence similarity 171, member A2
chr1_+_28454966 32.06 ENSRNOT00000078841
ENSRNOT00000030327
tumor protein D52-like 1
chr1_+_220335254 31.89 ENSRNOT00000072261
Ras and Rab interactor 1
chr3_-_10602672 30.55 ENSRNOT00000011648
neuronal calcium sensor 1
chr10_-_83332851 30.53 ENSRNOT00000007133
neurexophilin 3
chr1_+_89491654 30.52 ENSRNOT00000028632
leucine-rich repeat LGI family, member 4
chr4_-_119131202 30.17 ENSRNOT00000011675
anthrax toxin receptor 1
chr18_+_29966245 29.63 ENSRNOT00000074028
protocadherin alpha 4
chr3_-_39596718 29.28 ENSRNOT00000006784
reprimo, TP53 dependent G2 arrest mediator candidate
chr2_-_44907030 29.02 ENSRNOT00000013979
glutathione peroxidase 8
chr10_+_92288910 28.12 ENSRNOT00000006947
ENSRNOT00000045127
microtubule-associated protein tau
chr12_+_14092541 27.84 ENSRNOT00000033998
Rap associating with DIL domain
chr1_+_220428481 27.30 ENSRNOT00000027335
ras and Rab interactor 1
chr7_-_140483693 26.48 ENSRNOT00000089060
dendrin
chr12_-_30566032 25.16 ENSRNOT00000093378
glioblastoma amplified sequence
chr1_+_221792221 24.85 ENSRNOT00000054828
neurexin 2
chr11_+_86516390 24.63 ENSRNOT00000041168
glycoprotein Ib platelet beta subunit
chr18_+_29993361 24.34 ENSRNOT00000075810
protocadherin alpha 4
chr1_-_226924244 23.59 ENSRNOT00000028971
transmembrane protein 132A
chr7_+_123510804 23.56 ENSRNOT00000010491
septin 3
chr10_-_97582188 23.16 ENSRNOT00000005076
regulator of G-protein signaling 9
chr10_+_86303727 21.64 ENSRNOT00000037752
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr1_-_226353611 21.51 ENSRNOT00000037624
diacylglycerol lipase, alpha
chr16_+_21282467 21.43 ENSRNOT00000065345
YjeF N-terminal domain containing 3
chr10_+_108395860 20.90 ENSRNOT00000075796
glucosidase, alpha, acid
chr8_-_115981910 20.86 ENSRNOT00000019867
dedicator of cyto-kinesis 3
chr10_+_92289107 20.83 ENSRNOT00000050070
microtubule-associated protein tau
chr1_-_73753128 20.66 ENSRNOT00000068459
tweety family member 1
chr3_+_154395187 20.58 ENSRNOT00000050810
V-set and transmembrane domain containing 2 like
chr10_+_91187593 20.02 ENSRNOT00000004163
acyl-CoA binding domain containing 4
chr1_+_40389638 19.89 ENSRNOT00000021471
pleckstrin homology and RhoGEF domain containing G1
chr18_+_30515962 19.70 ENSRNOT00000027172
protocadherin beta-6-like
chr11_+_73738433 19.57 ENSRNOT00000002353
transmembrane protein 44
chr4_+_25825567 19.16 ENSRNOT00000009417
cyclin-dependent kinase 14
chr10_-_88266210 18.84 ENSRNOT00000090702
ENSRNOT00000020603
huntingtin-associated protein 1
chr12_-_23925741 18.83 ENSRNOT00000001957
serine/arginine repetitive matrix 3
chr7_-_117880289 18.70 ENSRNOT00000052227
Rho GTPase activating protein 39
chr18_+_30550877 18.69 ENSRNOT00000027164
protocadherin beta-7-like
chr18_+_30527705 18.57 ENSRNOT00000027168
protocadherin beta 14
chr12_+_24651314 18.07 ENSRNOT00000077016
ENSRNOT00000071569
VPS37D, ESCRT-I subunit
chr2_+_174013288 17.70 ENSRNOT00000013904
serpin family I member 1
chr10_-_31041626 17.67 ENSRNOT00000007267
LSM11, U7 small nuclear RNA associated
chr16_+_81616604 17.66 ENSRNOT00000026392
ENSRNOT00000057740
ADP-ribosylhydrolase like 1
growth hormone regulated TBC protein 1
chr18_+_30036887 17.64 ENSRNOT00000077824
protocadherin alpha 4
chrX_-_131343853 17.47 ENSRNOT00000038653
DDB1 and CUL4 associated factor 12-like 1
chr8_+_119566509 17.08 ENSRNOT00000028633
tetratricopeptide repeat and ankyrin repeat containing 1
chr9_+_10941613 16.57 ENSRNOT00000070794
semaphorin 6B
chr1_-_146226462 16.52 ENSRNOT00000036343
cell migration-inducing hyaluronan binding protein
chr17_-_9695292 16.46 ENSRNOT00000036162
proline rich 7 (synaptic)
chr3_-_80873887 16.41 ENSRNOT00000024280
diacylglycerol kinase zeta
chr5_+_79055521 16.31 ENSRNOT00000010333
collagen type XXVII alpha 1 chain
chr1_-_226292480 15.65 ENSRNOT00000039133
myelin regulatory factor
chr19_+_52086325 15.64 ENSRNOT00000020341
N-terminal EF-hand calcium binding protein 2
chr8_+_128972311 15.24 ENSRNOT00000025460
myosin VIIA and Rab interacting protein
chr3_-_57957346 15.19 ENSRNOT00000036728
solute carrier family 25 member 12
chr4_+_34962339 15.15 ENSRNOT00000086248

chr19_-_56311991 14.80 ENSRNOT00000014090
dysbindin domain containing 1
chr13_+_82072497 14.74 ENSRNOT00000063810
ENSRNOT00000085135
kinesin-associated protein 3
chr18_-_37776453 14.44 ENSRNOT00000087876
dihydropyrimidinase-like 3
chrX_-_105568343 14.31 ENSRNOT00000029807
armadillo repeat containing, X-linked 6
chr14_+_79538911 14.30 ENSRNOT00000009960
sortilin-related VPS10 domain containing receptor 2
chr7_+_140788987 14.23 ENSRNOT00000086611
potassium voltage-gated channel subfamily H member 3
chr10_+_35392762 14.23 ENSRNOT00000059277
RasGEF domain family, member 1C
chr8_-_110813000 14.08 ENSRNOT00000010634
Eph receptor B1
chr5_-_166133274 14.06 ENSRNOT00000078830
kinesin family member 1B
chr5_-_166133491 13.99 ENSRNOT00000087739
ENSRNOT00000089099
kinesin family member 1B
chr9_+_117583610 13.81 ENSRNOT00000088647
ENSRNOT00000049426
erythrocyte membrane protein band 4.1-like 3
chr19_-_26053762 13.73 ENSRNOT00000004646
microtubule associated serine/threonine kinase 1
chr12_+_47551935 13.58 ENSRNOT00000056932
RGD1560398
chr2_+_226900619 13.51 ENSRNOT00000019638
phosphodiesterase 5A
chr1_+_78818404 13.44 ENSRNOT00000090417
G protein subunit gamma 8
chr10_-_68517564 13.30 ENSRNOT00000086961
acid sensing ion channel subunit 2
chr8_-_47094352 13.20 ENSRNOT00000048347
glutamate ionotropic receptor kainate type subunit 4
chr3_-_148493225 13.04 ENSRNOT00000012141
p53 and DNA damage regulated 1
chr5_-_135025084 13.01 ENSRNOT00000018766
tetraspanin 1
chr7_-_70630338 12.96 ENSRNOT00000009803
GLI family zinc finger 1
chr2_-_80667481 12.96 ENSRNOT00000016784
trio Rho guanine nucleotide exchange factor
chr2_+_207923775 12.89 ENSRNOT00000019997
ENSRNOT00000051835
potassium voltage-gated channel subfamily D member 3
chr13_-_74923402 12.81 ENSRNOT00000033324
RAS protein activator like 2
chr3_-_9326993 12.67 ENSRNOT00000090137
laminin subunit gamma 3
chr2_-_188561267 12.56 ENSRNOT00000089781
ENSRNOT00000092093
tripartite motif-containing 46
chr9_-_19749145 12.40 ENSRNOT00000013956
regulator of calcineurin 2
chr12_+_18074033 12.39 ENSRNOT00000001727
integrator complex subunit 1-like
chrX_+_6273733 12.28 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr13_+_110920830 12.08 ENSRNOT00000077014
ENSRNOT00000076362
potassium voltage-gated channel subfamily H member 1
chr10_+_105861743 12.05 ENSRNOT00000064410
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr6_-_91250138 11.90 ENSRNOT00000052408
ninein-like
chr3_-_2803574 11.77 ENSRNOT00000040995
similar to Gene model 996
chr16_-_24788740 11.66 ENSRNOT00000018952
neuropeptide Y receptor Y1
chr3_+_146546387 11.64 ENSRNOT00000009946
ectonucleoside triphosphate diphosphohydrolase 6
chr11_+_36497509 11.55 ENSRNOT00000002222
tryptophan rich basic protein
chr10_+_40543288 11.55 ENSRNOT00000016755
solute carrier family 36 member 1
chr4_-_171176581 11.49 ENSRNOT00000030850
RAS-like, estrogen-regulated, growth-inhibitor
chr1_-_219532609 11.26 ENSRNOT00000025641
ankyrin repeat domain 13D
chr4_+_140837745 11.21 ENSRNOT00000080663
ADP-ribosylation factor like GTPase 8B
chr8_-_65587427 11.10 ENSRNOT00000016491
leucine rich repeat containing 49
chr10_+_764421 11.07 ENSRNOT00000084608
ENSRNOT00000087567
myosin heavy chain 11
chr7_-_12793711 11.01 ENSRNOT00000013762
paralemmin
chr8_-_72836159 11.00 ENSRNOT00000024617
tropomyosin 1, alpha
chr1_+_127802978 10.96 ENSRNOT00000055877
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr10_+_69737328 10.83 ENSRNOT00000055999
ENSRNOT00000076773
transmembrane protein 132E
chr3_+_123754057 10.83 ENSRNOT00000034201
ENSRNOT00000084671
adaptor-related protein complex 5, sigma 1 subunit
chr1_-_254671596 10.75 ENSRNOT00000025450
5-hydroxytryptamine receptor 7
chr2_+_195719543 10.74 ENSRNOT00000028324
CUGBP, Elav-like family member 3
chr3_+_146980923 10.67 ENSRNOT00000011654
NSFL1 cofactor
chr13_+_67611708 10.57 ENSRNOT00000063833
translocated promoter region, nuclear basket protein
chr6_-_128989812 10.47 ENSRNOT00000085943
ankyrin repeat and SOCS box protein 2-like
chr18_+_30487264 10.46 ENSRNOT00000040125
protocadherin beta 10
chr7_+_34001506 10.41 ENSRNOT00000005762
cyclin-dependent kinase 17
chr13_-_51992693 10.38 ENSRNOT00000008282
G protein-coupled receptor 37-like 1
chr16_+_81204766 10.37 ENSRNOT00000042465
transmembrane protein 255B
chr12_+_49328977 10.35 ENSRNOT00000000898
small G protein signaling modulator 1
chr2_-_198834038 10.31 ENSRNOT00000031484
nudix hydrolase 17
chr7_+_142397371 9.97 ENSRNOT00000040890
ENSRNOT00000065379
solute carrier family 4 member 8
chr1_+_47605415 9.94 ENSRNOT00000034842
fibronectin type III domain containing 1
chr4_+_77519028 9.81 ENSRNOT00000008743
zinc finger protein 398
chr17_+_31493107 9.75 ENSRNOT00000023611
ENSRNOT00000086264
tubulin, beta 2A class IIa
chr17_+_77601877 9.67 ENSRNOT00000091554
ENSRNOT00000024872
pre-mRNA processing factor 18
chr6_-_137733026 9.57 ENSRNOT00000019213
jagged 2
chr4_-_82295470 9.50 ENSRNOT00000091073
homeobox A10
chr1_+_261415191 9.47 ENSRNOT00000083287
ENSRNOT00000040740
zinc finger FYVE-type containing 27
chr1_+_47605262 9.46 ENSRNOT00000089458
fibronectin type III domain containing 1
chr13_-_51076165 9.44 ENSRNOT00000004602
adenosine A1 receptor
chr6_-_45629168 9.41 ENSRNOT00000009877
ring finger protein 144A
chr17_+_11953552 9.38 ENSRNOT00000090782
receptor tyrosine kinase-like orphan receptor 2
chr14_+_77712240 9.37 ENSRNOT00000009101
msh homeobox 1
chr7_+_141702038 9.32 ENSRNOT00000086577
disco-interacting protein 2 homolog B
chr19_-_37245217 9.30 ENSRNOT00000020927
hypothetical protein LOC688735
chr11_+_84396033 9.22 ENSRNOT00000002316
ATP binding cassette subfamily C member 5
chr12_+_22026075 9.10 ENSRNOT00000029041
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1-like
chr1_-_254671778 9.03 ENSRNOT00000025493
5-hydroxytryptamine receptor 7
chr16_-_54450426 8.95 ENSRNOT00000014623
platelet-derived growth factor receptor-like
chr4_-_82209933 8.94 ENSRNOT00000091106
homeobox protein Hox-A10-like
chr3_+_2648885 8.94 ENSRNOT00000020339
ATP binding cassette subfamily A member 2
chr1_-_85517360 8.86 ENSRNOT00000026114
EP300 interacting inhibitor of differentiation 2
chr2_+_251817694 8.85 ENSRNOT00000019964
similar to RIKEN cDNA 2410004B18
chr8_-_62987182 8.82 ENSRNOT00000070885
immunoglobulin superfamily containing leucine-rich repeat 2
chr9_-_15306465 8.71 ENSRNOT00000019404
fibroblast growth factor receptor substrate 3
chr10_-_57309298 8.69 ENSRNOT00000056622
calmodulin binding transcription activator 2
chr3_-_110140756 8.66 ENSRNOT00000007882
G protein-coupled receptor 176
chr7_-_125407806 8.66 ENSRNOT00000084666
similar to mKIAA1644 protein
chr1_+_101427195 8.64 ENSRNOT00000028271
glycogen synthase 1
chr13_+_110257571 8.62 ENSRNOT00000005715
integrator complex subunit 7
chr18_+_30913842 8.60 ENSRNOT00000026947
protocadherin gamma subfamily C, 3
chr5_+_104941066 8.59 ENSRNOT00000009225
Ras-related GTP binding A
chr14_-_84170301 8.57 ENSRNOT00000080413
solute carrier family 35, member E4
chr3_+_2512492 8.54 ENSRNOT00000074026

chr5_+_70441123 8.42 ENSRNOT00000087517
fibronectin type III and SPRY domain containing 1-like
chrX_-_35431164 8.40 ENSRNOT00000004968
sex comb on midleg-like 2 (Drosophila)
chr8_-_49045154 8.38 ENSRNOT00000088034
pleckstrin homology-like domain, family B, member 1
chr10_+_48240127 8.32 ENSRNOT00000080682
sperm antigen with calponin homology and coiled-coil domains 1
chr11_-_88343627 8.28 ENSRNOT00000002530
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr7_+_12022285 8.22 ENSRNOT00000024080
RNA exonuclease 1 homolog
chr1_+_218466289 8.19 ENSRNOT00000017948
MAS related GPR family member F
chr14_-_18076907 8.15 ENSRNOT00000003472
prostate androgen-regulated mucin-like protein 1
chr1_-_100671074 7.93 ENSRNOT00000027132
myosin heavy chain 14
chr18_+_30375798 7.92 ENSRNOT00000060497
protocadherin beta 2
chr6_+_136720266 7.85 ENSRNOT00000018278
kinesin family member 26A
chr7_+_47928060 7.84 ENSRNOT00000005740
coiled-coil domain containing 59
chr10_+_48240330 7.75 ENSRNOT00000057798
sperm antigen with calponin homology and coiled-coil domains 1
chr7_-_83701447 7.70 ENSRNOT00000088893

chr4_-_155561324 7.67 ENSRNOT00000085447
solute carrier family 2 member 3
chr1_-_213981317 7.67 ENSRNOT00000086238
ENSRNOT00000054869
solute carrier family 25 member 22
chr9_-_93735636 7.63 ENSRNOT00000025582
natriuretic peptide C
chr2_-_187133993 7.62 ENSRNOT00000019502
platelet endothelial aggregation receptor 1
chr1_+_40529045 7.47 ENSRNOT00000026564
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr11_-_65350442 7.46 ENSRNOT00000003773
G protein-coupled receptor 156
chr17_-_79676499 7.46 ENSRNOT00000022711
integrin subunit alpha 8
chr9_+_16702460 7.31 ENSRNOT00000061432
protein tyrosine kinase 7
chrX_+_108287068 7.31 ENSRNOT00000093348
interleukin 1 receptor accessory protein-like 2
chr15_+_45712821 7.31 ENSRNOT00000083381
ENSRNOT00000045833
family with sequence similarity 124 member A
chr7_-_130176696 7.30 ENSRNOT00000051347
DENN domain containing 6B
chr6_-_46631983 7.30 ENSRNOT00000045963
SRY box 11
chr19_+_37652969 7.21 ENSRNOT00000041970
capping protein regulator and myosin 1 linker 2
chr3_-_82734520 7.14 ENSRNOT00000083743
ENSRNOT00000012161
exostosin glycosyltransferase 2
chr1_+_105113595 7.13 ENSRNOT00000020853
ENSRNOT00000079655
protein arginine methyltransferase 3
chr12_+_28212333 7.13 ENSRNOT00000001182
autism susceptibility candidate 2
chr6_-_33507542 7.10 ENSRNOT00000007928
growth differentiation factor 7
chr7_+_54031316 7.06 ENSRNOT00000039096
Bardet-Biedl syndrome 10
chr6_-_124735741 7.03 ENSRNOT00000064716
ENSRNOT00000091693
ribosomal protein S6 kinase A5
chr8_-_32000378 7.01 ENSRNOT00000013341
ADAM metallopeptidase with thrombospondin type 1 motif, 15

Network of associatons between targets according to the STRING database.

First level regulatory network of Ctcfl_Ctcf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.0 43.9 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
9.0 45.0 GO:0061743 motor learning(GO:0061743)
8.6 59.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
7.5 59.8 GO:0035934 corticosterone secretion(GO:0035934)
7.0 55.9 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
7.0 20.9 GO:0002086 diaphragm contraction(GO:0002086)
6.3 18.8 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
6.1 49.0 GO:0090258 negative regulation of mitochondrial fission(GO:0090258) regulation of cellular response to heat(GO:1900034)
5.8 57.8 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
5.6 28.1 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
5.4 21.5 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
4.9 19.8 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
4.7 9.4 GO:1900453 negative regulation of long term synaptic depression(GO:1900453)
4.5 13.5 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
4.5 44.8 GO:0046684 response to pyrethroid(GO:0046684)
4.4 17.7 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
4.4 13.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
4.3 30.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
4.1 24.9 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
3.8 15.2 GO:0070778 malate-aspartate shuttle(GO:0043490) L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
3.8 30.2 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
3.7 7.5 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
3.7 25.9 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
3.7 11.0 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
3.6 10.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
3.5 10.6 GO:0000189 MAPK import into nucleus(GO:0000189) regulation of chromatin assembly(GO:0010847) positive regulation of chromatin assembly or disassembly(GO:0045799)
3.4 23.9 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
3.2 9.7 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
3.1 9.4 GO:2001055 embryonic nail plate morphogenesis(GO:0035880) positive regulation of mesenchymal cell apoptotic process(GO:2001055)
3.1 9.4 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
3.1 21.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
3.0 8.9 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
2.9 17.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
2.9 31.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
2.8 11.0 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
2.6 13.0 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
2.5 7.5 GO:0015942 formate metabolic process(GO:0015942)
2.4 7.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
2.4 7.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
2.3 11.6 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
2.3 13.8 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
2.2 13.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
2.1 14.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
2.1 8.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
2.1 316.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
2.1 20.8 GO:0034472 snRNA 3'-end processing(GO:0034472)
2.0 12.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.9 13.3 GO:0050915 sensory perception of sour taste(GO:0050915)
1.8 7.3 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
1.8 7.2 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
1.8 7.0 GO:0043988 histone H3-S10 phosphorylation(GO:0043987) histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
1.7 10.4 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
1.7 8.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
1.6 11.5 GO:0015808 L-alanine transport(GO:0015808)
1.6 6.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.6 18.1 GO:0030432 peristalsis(GO:0030432)
1.6 6.4 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.6 33.4 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
1.6 6.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
1.4 12.9 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
1.4 12.6 GO:0099612 protein localization to axon(GO:0099612)
1.4 9.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
1.3 4.0 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
1.3 11.9 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
1.2 6.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.2 9.6 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
1.2 7.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
1.2 7.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.2 14.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
1.1 4.6 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
1.1 30.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
1.1 37.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
1.1 3.4 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
1.1 11.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.1 7.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
1.1 5.3 GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.0 6.3 GO:0098597 vocal learning(GO:0042297) imitative learning(GO:0098596) observational learning(GO:0098597)
1.0 8.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
1.0 5.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
1.0 4.9 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
1.0 19.4 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
1.0 5.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
1.0 12.4 GO:0007614 short-term memory(GO:0007614)
0.9 3.7 GO:0051542 elastin biosynthetic process(GO:0051542)
0.9 3.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.9 5.4 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.9 44.5 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.9 6.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.9 3.5 GO:0034696 response to prostaglandin F(GO:0034696)
0.8 13.4 GO:0019236 response to pheromone(GO:0019236)
0.8 3.3 GO:0003383 apical constriction(GO:0003383)
0.8 2.3 GO:0071461 cellular response to redox state(GO:0071461)
0.8 7.7 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.8 10.7 GO:0051764 actin crosslink formation(GO:0051764)
0.8 10.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.7 11.8 GO:0071625 vocalization behavior(GO:0071625)
0.7 10.7 GO:0030575 nuclear body organization(GO:0030575)
0.7 6.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.7 8.4 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.7 7.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.7 1.3 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.7 12.7 GO:0014002 astrocyte development(GO:0014002)
0.7 7.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.7 5.3 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.7 5.3 GO:0061193 taste bud development(GO:0061193)
0.6 23.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.6 5.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.6 2.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.6 16.4 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.6 1.7 GO:0008592 regulation of Toll signaling pathway(GO:0008592) negative regulation of Toll signaling pathway(GO:0045751) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.5 3.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.5 4.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.5 4.3 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.5 4.3 GO:0016926 protein desumoylation(GO:0016926)
0.5 3.8 GO:0035754 B cell chemotaxis(GO:0035754)
0.5 6.0 GO:0006527 arginine catabolic process(GO:0006527)
0.5 8.7 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.5 1.8 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.5 5.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 7.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 7.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.4 2.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.4 3.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.4 2.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.4 6.2 GO:0043090 amino acid import(GO:0043090)
0.4 13.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 1.2 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.4 11.6 GO:0032026 response to magnesium ion(GO:0032026)
0.4 7.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.4 6.5 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.4 5.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.4 4.0 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.4 0.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.4 1.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 3.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.3 19.2 GO:0046847 filopodium assembly(GO:0046847)
0.3 1.4 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.3 10.2 GO:0060065 uterus development(GO:0060065)
0.3 2.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.3 4.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.3 1.3 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.3 8.7 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.3 28.4 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.3 10.0 GO:0015701 bicarbonate transport(GO:0015701)
0.3 4.5 GO:0048243 norepinephrine secretion(GO:0048243)
0.3 5.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 3.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 3.5 GO:0060746 parental behavior(GO:0060746)
0.3 1.5 GO:0046098 guanine metabolic process(GO:0046098)
0.3 3.3 GO:0051014 actin filament severing(GO:0051014)
0.3 2.6 GO:0015886 heme transport(GO:0015886)
0.3 8.5 GO:0030199 collagen fibril organization(GO:0030199)
0.3 12.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.3 0.8 GO:0021626 hindbrain maturation(GO:0021578) cerebellum maturation(GO:0021590) central nervous system maturation(GO:0021626) cerebellar cortex maturation(GO:0021699)
0.3 0.5 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 5.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 4.3 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.2 0.7 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)
0.2 5.6 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 5.0 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.2 0.9 GO:0032364 oxygen homeostasis(GO:0032364)
0.2 8.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.2 2.0 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.2 2.8 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.2 3.5 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 24.9 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.2 10.4 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 1.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 5.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 1.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 0.4 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.2 80.0 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.2 13.0 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.2 2.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 1.0 GO:0097435 fibril organization(GO:0097435)
0.2 6.8 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.2 1.8 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.2 5.5 GO:0018345 protein palmitoylation(GO:0018345)
0.2 4.8 GO:0030517 negative regulation of axon extension(GO:0030517)
0.2 9.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.2 0.8 GO:0033625 positive regulation of integrin activation(GO:0033625) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 1.6 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 15.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 4.8 GO:0001893 maternal placenta development(GO:0001893)
0.1 2.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 12.1 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.1 4.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 2.1 GO:0007035 vacuolar acidification(GO:0007035)
0.1 4.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.5 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 17.1 GO:0007596 blood coagulation(GO:0007596)
0.1 7.4 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 1.9 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 0.4 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.4 GO:0019541 acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
0.1 2.7 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.1 7.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 10.1 GO:0007050 cell cycle arrest(GO:0007050)
0.1 8.0 GO:0030308 negative regulation of cell growth(GO:0030308)
0.1 1.5 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 11.5 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.1 1.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 3.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.1 3.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of trophoblast cell migration(GO:1901165)
0.1 2.8 GO:0032418 lysosome localization(GO:0032418)
0.1 4.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 1.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 4.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 9.7 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 0.9 GO:0042407 cristae formation(GO:0042407)
0.1 3.9 GO:0019233 sensory perception of pain(GO:0019233)
0.1 6.2 GO:0030198 extracellular matrix organization(GO:0030198)
0.1 2.9 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 1.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 8.3 GO:0048812 neuron projection morphogenesis(GO:0048812)
0.0 4.0 GO:0050808 synapse organization(GO:0050808)
0.0 1.0 GO:1901998 toxin transport(GO:1901998)
0.0 1.4 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 2.7 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.4 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 3.4 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.8 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 1.5 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 3.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0006882 cellular zinc ion homeostasis(GO:0006882)
0.0 0.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.3 GO:0001510 RNA methylation(GO:0001510)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
12.2 49.0 GO:0045298 tubulin complex(GO:0045298)
7.9 158.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
4.7 23.6 GO:0099569 presynaptic cytoskeleton(GO:0099569)
4.1 20.7 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
4.1 81.4 GO:0043196 varicosity(GO:0043196)
3.6 10.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
3.1 12.6 GO:1990769 proximal neuron projection(GO:1990769)
3.1 28.1 GO:0071821 FANCM-MHF complex(GO:0071821)
3.0 45.0 GO:0043083 synaptic cleft(GO:0043083)
3.0 44.9 GO:0032591 dendritic spine membrane(GO:0032591)
3.0 47.8 GO:0005883 neurofilament(GO:0005883)
2.9 14.7 GO:0016939 kinesin II complex(GO:0016939)
2.9 44.1 GO:0031045 dense core granule(GO:0031045)
2.8 47.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
2.5 17.7 GO:0005683 U7 snRNP(GO:0005683)
2.3 73.6 GO:0005921 gap junction(GO:0005921)
2.2 11.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.2 13.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
2.0 18.1 GO:0000813 ESCRT I complex(GO:0000813)
2.0 7.9 GO:0097513 myosin II filament(GO:0097513)
1.8 14.4 GO:0016272 prefoldin complex(GO:0016272)
1.8 7.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
1.7 30.9 GO:0031258 lamellipodium membrane(GO:0031258)
1.7 8.6 GO:1990130 Iml1 complex(GO:1990130)
1.6 6.5 GO:0070876 SOSS complex(GO:0070876)
1.6 8.0 GO:0005608 laminin-3 complex(GO:0005608)
1.6 25.7 GO:0032039 integrator complex(GO:0032039)
1.6 11.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.4 16.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.3 10.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.2 36.5 GO:0030673 axolemma(GO:0030673)
1.2 9.5 GO:0032584 growth cone membrane(GO:0032584)
1.2 47.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.1 6.6 GO:1990246 uniplex complex(GO:1990246)
1.1 5.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
1.1 10.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
1.0 12.7 GO:0097542 ciliary tip(GO:0097542)
0.8 14.1 GO:0032433 filopodium tip(GO:0032433)
0.7 7.2 GO:0044352 F-actin capping protein complex(GO:0008290) pinosome(GO:0044352) macropinosome(GO:0044354)
0.7 12.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.7 2.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.6 24.4 GO:1904115 axon cytoplasm(GO:1904115)
0.6 1.8 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.5 9.7 GO:0005682 U5 snRNP(GO:0005682)
0.5 8.4 GO:0045180 basal cortex(GO:0045180)
0.5 16.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.5 1.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.5 108.1 GO:0070382 exocytic vesicle(GO:0070382)
0.5 2.8 GO:0016461 unconventional myosin complex(GO:0016461)
0.5 6.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 2.7 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.4 6.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 10.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.4 33.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4 8.4 GO:0001741 XY body(GO:0001741)
0.4 7.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.4 2.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.4 3.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 4.2 GO:0002177 manchette(GO:0002177)
0.4 3.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.4 10.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.4 3.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.4 17.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 74.0 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.3 365.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.3 3.4 GO:0071564 npBAF complex(GO:0071564)
0.3 3.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.3 2.0 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290)
0.3 1.4 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.3 4.3 GO:0036038 MKS complex(GO:0036038)
0.3 2.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 13.2 GO:0005871 kinesin complex(GO:0005871)
0.2 28.3 GO:0098793 presynapse(GO:0098793)
0.2 6.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 2.1 GO:0005686 U2 snRNP(GO:0005686)
0.2 1.7 GO:0042587 glycogen granule(GO:0042587)
0.2 1.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 4.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 3.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 13.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 1.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 3.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.7 GO:0031010 ISWI-type complex(GO:0031010)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 3.0 GO:0031901 early endosome membrane(GO:0031901)
0.1 4.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) Ku70:Ku80 complex(GO:0043564)
0.1 1.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 9.2 GO:0005604 basement membrane(GO:0005604)
0.1 25.8 GO:0016607 nuclear speck(GO:0016607)
0.1 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 19.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 5.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 34.8 GO:0005783 endoplasmic reticulum(GO:0005783)
0.1 2.3 GO:0001772 immunological synapse(GO:0001772)
0.1 8.2 GO:0005770 late endosome(GO:0005770)
0.1 0.2 GO:0070820 tertiary granule(GO:0070820)
0.1 4.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 21.5 GO:0005874 microtubule(GO:0005874)
0.1 1.4 GO:0031594 neuromuscular junction(GO:0031594)
0.1 4.5 GO:0005769 early endosome(GO:0005769)
0.1 1.6 GO:0032040 small-subunit processome(GO:0032040)
0.1 2.4 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 5.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 17.8 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.4 GO:0005902 microvillus(GO:0005902)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 2.6 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 16.8 GO:0009986 cell surface(GO:0009986)
0.0 2.1 GO:0016234 inclusion body(GO:0016234)
0.0 16.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 123.1 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
13.6 81.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)
12.2 49.0 GO:0099609 microtubule lateral binding(GO:0099609)
7.6 30.6 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
7.0 20.9 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
6.9 20.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
5.9 17.7 GO:0071209 U7 snRNA binding(GO:0071209)
5.7 158.5 GO:0031402 sodium ion binding(GO:0031402)
5.5 11.0 GO:0031750 D3 dopamine receptor binding(GO:0031750)
4.7 28.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
4.3 30.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
3.8 11.5 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
3.8 18.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
3.6 18.1 GO:0001601 peptide YY receptor activity(GO:0001601)
3.6 24.9 GO:0097109 neuroligin family protein binding(GO:0097109)
3.3 16.5 GO:0046923 ER retention sequence binding(GO:0046923)
3.3 19.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
3.2 9.7 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
3.1 12.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
3.0 15.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
3.0 12.0 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
2.9 11.6 GO:0045134 uridine-diphosphatase activity(GO:0045134)
2.6 12.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
2.6 7.7 GO:0033222 xylose binding(GO:0033222)
2.3 14.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
2.1 8.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
2.0 6.0 GO:0016403 dimethylargininase activity(GO:0016403)
1.9 9.4 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
1.9 13.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.9 7.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.8 7.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
1.8 10.9 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.8 14.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.5 10.7 GO:0097322 7SK snRNA binding(GO:0097322)
1.5 7.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.5 7.5 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
1.5 13.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
1.4 19.8 GO:0051378 serotonin binding(GO:0051378)
1.4 5.6 GO:0031705 bombesin receptor binding(GO:0031705)
1.4 16.4 GO:0001727 lipid kinase activity(GO:0001727)
1.3 4.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.3 10.6 GO:0043495 protein anchor(GO:0043495)
1.3 16.6 GO:0030215 semaphorin receptor binding(GO:0030215)
1.3 29.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
1.2 8.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
1.2 7.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
1.1 4.3 GO:0008158 hedgehog receptor activity(GO:0008158)
1.1 29.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
1.0 4.2 GO:0019002 GMP binding(GO:0019002)
1.0 4.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
1.0 17.7 GO:0016854 racemase and epimerase activity(GO:0016854)
1.0 6.8 GO:0019958 C-X-C chemokine binding(GO:0019958)
1.0 13.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.9 4.6 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.9 33.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.9 5.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.9 6.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.9 41.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.8 5.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.7 3.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.7 17.7 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.7 30.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.7 7.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.7 20.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.7 5.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.7 4.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.7 5.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.7 2.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.6 6.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.6 7.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.6 3.8 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.6 2.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.6 2.5 GO:0034618 arginine-tRNA ligase activity(GO:0004814) arginine binding(GO:0034618)
0.6 6.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.6 11.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.6 2.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.6 161.2 GO:0005096 GTPase activator activity(GO:0005096)
0.6 5.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.5 5.4 GO:0015386 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.5 385.4 GO:0005509 calcium ion binding(GO:0005509)
0.5 7.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.5 4.8 GO:0034511 U3 snoRNA binding(GO:0034511)
0.4 13.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 5.6 GO:0015026 coreceptor activity(GO:0015026)
0.4 4.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.4 9.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.4 19.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 7.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.4 5.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.4 2.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.4 10.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.4 3.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3 13.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3 52.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.3 3.9 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
0.3 8.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 6.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 2.6 GO:0015232 heme transporter activity(GO:0015232)
0.3 19.3 GO:0005518 collagen binding(GO:0005518)
0.3 14.7 GO:0019894 kinesin binding(GO:0019894)
0.3 0.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 8.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3 10.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 15.2 GO:0017022 myosin binding(GO:0017022)
0.2 3.9 GO:0004659 prenyltransferase activity(GO:0004659)
0.2 0.2 GO:0030984 kininogen binding(GO:0030984)
0.2 1.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 1.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 7.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 3.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 17.0 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.2 19.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 6.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 2.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 14.4 GO:0051082 unfolded protein binding(GO:0051082)
0.2 0.7 GO:0005534 galactose binding(GO:0005534)
0.2 4.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 3.2 GO:0001671 ATPase activator activity(GO:0001671)
0.2 5.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 17.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 9.5 GO:0043621 protein self-association(GO:0043621)
0.1 2.1 GO:0031996 thioesterase binding(GO:0031996)
0.1 1.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 2.9 GO:0050681 androgen receptor binding(GO:0050681)
0.1 2.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.7 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 9.1 GO:0035326 enhancer binding(GO:0035326)
0.1 1.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 6.2 GO:0046332 SMAD binding(GO:0046332)
0.1 9.7 GO:0005267 potassium channel activity(GO:0005267)
0.1 3.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 15.1 GO:0008017 microtubule binding(GO:0008017)
0.1 0.9 GO:0031005 filamin binding(GO:0031005)
0.1 2.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.5 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 8.6 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 11.8 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 1.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.7 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 49.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.9 30.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
1.8 47.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
1.8 70.5 PID RAS PATHWAY Regulation of Ras family activation
0.9 23.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.5 17.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.5 9.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.5 18.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.5 8.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.5 16.3 NABA COLLAGENS Genes encoding collagen proteins
0.4 14.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.4 14.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.4 3.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.4 23.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.4 25.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.4 16.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.4 7.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 13.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.3 11.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.3 7.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 8.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.3 15.9 PID SHP2 PATHWAY SHP2 signaling
0.2 41.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 3.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 4.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 9.6 PID NOTCH PATHWAY Notch signaling pathway
0.1 8.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 14.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.0 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1 4.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 59.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
2.0 18.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
1.8 52.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.7 55.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.6 24.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.6 17.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.4 19.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
1.1 9.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.0 13.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.0 24.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
1.0 14.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.9 24.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.9 44.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.9 28.0 REACTOME KINESINS Genes involved in Kinesins
0.8 21.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.7 22.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.6 32.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.6 10.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.6 9.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.5 9.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 13.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.5 9.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.5 10.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.5 7.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.4 15.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.4 7.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.4 7.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.4 10.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.4 9.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.3 12.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.3 8.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.3 7.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3 2.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3 8.7 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.3 11.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 4.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 2.1 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.3 13.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 7.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 41.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 13.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 3.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 15.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 1.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 4.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 4.8 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 5.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 5.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 3.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 2.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis