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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Crx_Gsc

Z-value: 0.83

Motif logo

Transcription factors associated with Crx_Gsc

Gene Symbol Gene ID Gene Info
ENSRNOG00000013890 cone-rod homeobox
ENSRNOG00000010605 goosecoid homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Crxrn6_v1_chr1_-_77750960_777509600.241.1e-05Click!
Gscrn6_v1_chr6_-_128149220_128149220-0.233.4e-05Click!

Activity profile of Crx_Gsc motif

Sorted Z-values of Crx_Gsc motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_57207656 31.89 ENSRNOT00000038207
ENSRNOT00000085754
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr1_+_266781617 22.58 ENSRNOT00000027417
internexin neuronal intermediate filament protein, alpha
chr1_-_266074181 21.28 ENSRNOT00000026378
pleckstrin and Sec7 domain containing
chr4_+_94696965 18.93 ENSRNOT00000064696
glutamate ionotropic receptor delta type subunit 2
chr8_-_85645718 18.63 ENSRNOT00000032185
glutathione S-transferase alpha 2
chr19_+_10731855 18.60 ENSRNOT00000022277
plasmolipin
chr1_+_100393303 18.35 ENSRNOT00000026251
synaptotagmin 3
chr10_-_27366665 18.27 ENSRNOT00000004725
gamma-aminobutyric acid type A receptor alpha1 subunit
chr10_-_58693754 16.17 ENSRNOT00000071764
PITPNM family member 3
chr17_+_81455955 15.50 ENSRNOT00000044313
solute carrier family 39 member 12
chr3_+_113318563 15.38 ENSRNOT00000089230
creatine kinase, mitochondrial 1
chr10_+_5930298 14.05 ENSRNOT00000044626
glutamate ionotropic receptor NMDA type subunit 2A
chr12_-_8418966 14.01 ENSRNOT00000085869
microtubule associated tumor suppressor candidate 2
chr4_+_84423653 13.97 ENSRNOT00000012655
chimerin 2
chr4_+_22445414 13.91 ENSRNOT00000087657
ENSRNOT00000030224
RUN domain containing 3B
chr10_+_65586504 13.82 ENSRNOT00000015535
ENSRNOT00000046388
aldolase, fructose-bisphosphate C
chr5_+_139783951 13.44 ENSRNOT00000081333
regulating synaptic membrane exocytosis 3
chr4_-_108717309 13.23 ENSRNOT00000085062

chr12_-_41448668 13.19 ENSRNOT00000001856
RAS protein activator like 1 (GAP1 like)
chrX_-_19134869 13.12 ENSRNOT00000004235
Ras-related GTP binding B
chrX_-_19369746 13.10 ENSRNOT00000075249
ras-related GTP-binding protein B
chr4_+_150133590 12.79 ENSRNOT00000051804
RasGEF domain family, member 1A
chr7_-_13751271 12.33 ENSRNOT00000009931
solute carrier family 1 member 6
chr3_+_159936856 12.22 ENSRNOT00000078703
hepatocyte nuclear factor 4, alpha
chr10_+_86303727 11.62 ENSRNOT00000037752
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_+_133457255 11.50 ENSRNOT00000080621
contactin 1
chr7_-_117732339 11.46 ENSRNOT00000092917
ENSRNOT00000020696
forkhead box H1
chr13_-_72367980 11.40 ENSRNOT00000003928
calcium voltage-gated channel subunit alpha1 E
chr18_+_59748444 11.38 ENSRNOT00000024752
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr12_-_10307265 11.29 ENSRNOT00000092627
WAS protein family, member 3
chr13_+_63526486 10.45 ENSRNOT00000003788
BMP/retinoic acid inducible neural specific 3
chr2_-_115836846 10.34 ENSRNOT00000014359
claudin 11
chr1_-_248376750 10.25 ENSRNOT00000089073
glycine decarboxylase
chr14_+_8182383 9.55 ENSRNOT00000092719
mitogen activated protein kinase 10
chr13_+_77485113 9.30 ENSRNOT00000080254
tenascin R
chr5_-_9094616 9.28 ENSRNOT00000072210
serum/glucocorticoid regulated kinase family, member 3
chr10_+_92288910 9.17 ENSRNOT00000006947
ENSRNOT00000045127
microtubule-associated protein tau
chr20_+_28572242 9.04 ENSRNOT00000072485
SH3 domain containing ring finger 3
chrX_-_115764217 8.78 ENSRNOT00000009400
transient receptor potential cation channel, subfamily C, member 5
chr10_+_54512983 8.75 ENSRNOT00000005204
syntaxin 8
chr18_+_25749098 8.60 ENSRNOT00000027771
calcium/calmodulin-dependent protein kinase IV
chr7_+_123482255 8.34 ENSRNOT00000064487
hypothetical protein LOC688613
chr11_-_59110562 8.25 ENSRNOT00000047907
ENSRNOT00000042024
limbic system-associated membrane protein
chr2_+_127489771 7.99 ENSRNOT00000093581
inturned planar cell polarity protein
chrX_+_122808605 7.88 ENSRNOT00000017567
zinc finger CCHC-type containing 12
chr7_+_11582984 7.87 ENSRNOT00000026893
G protein subunit gamma 7
chr2_+_115337439 7.69 ENSRNOT00000015779
eukaryotic translation initiation factor 5A2
chr6_-_107325345 7.65 ENSRNOT00000049481
ENSRNOT00000042594
ENSRNOT00000013026
NUMB, endocytic adaptor protein
chr19_+_59186673 7.62 ENSRNOT00000071655
solute carrier family 35, member F3
chr1_-_189199376 7.59 ENSRNOT00000021027
uromodulin
chr17_+_31493107 7.59 ENSRNOT00000023611
ENSRNOT00000086264
tubulin, beta 2A class IIa
chr5_-_135025084 7.50 ENSRNOT00000018766
tetraspanin 1
chr5_+_64326733 7.50 ENSRNOT00000065775
transmembrane protein with EGF-like and two follistatin-like domains 1
chr4_+_117962319 7.45 ENSRNOT00000057441
transforming growth factor alpha
chr1_-_214844858 7.22 ENSRNOT00000046344
toll interacting protein
chr19_+_6046665 7.18 ENSRNOT00000084126
cadherin 8
chr19_+_51985170 7.14 ENSRNOT00000019443
heat shock factor binding protein 1
chr18_-_37096132 7.14 ENSRNOT00000041188
protein phosphatase 2, regulatory subunit B, beta
chr4_-_51199570 7.10 ENSRNOT00000010788
solute carrier family 13 member 1
chrX_+_76083549 7.07 ENSRNOT00000003573
MAGE family member E1
chr15_+_48674380 6.98 ENSRNOT00000018762
F-box protein 16
chrX_-_15620841 6.85 ENSRNOT00000085397
PRA1 domain family, member 2
chr4_-_16669368 6.81 ENSRNOT00000007608
piccolo (presynaptic cytomatrix protein)
chr9_+_95256627 6.70 ENSRNOT00000025291
UDP glucuronosyltransferase family 1 member A5
chr6_-_114476723 6.67 ENSRNOT00000005162
deiodinase, iodothyronine, type II
chr8_+_39848448 6.64 ENSRNOT00000012248
hepatocyte cell adhesion molecule
chr15_+_19547871 6.56 ENSRNOT00000036235
G protein-coupled receptor 137C
chr10_+_69737328 6.54 ENSRNOT00000055999
ENSRNOT00000076773
transmembrane protein 132E
chr12_-_19167015 6.50 ENSRNOT00000001797
gap junction protein, gamma 3
chr8_+_33514042 6.49 ENSRNOT00000081614
ENSRNOT00000081525
potassium voltage-gated channel subfamily J member 1
chr2_+_66940057 6.45 ENSRNOT00000043050
cadherin 9
chr13_+_31081804 6.23 ENSRNOT00000041413
cadherin 7
chr19_-_9931930 6.22 ENSRNOT00000085144
coiled-coil domain containing 113
chr13_-_70625842 6.11 ENSRNOT00000092499
laminin subunit gamma 2
chr18_+_30010918 6.10 ENSRNOT00000084132
protocadherin alpha 4
chr7_-_142352382 5.91 ENSRNOT00000048488
polypeptide N-acetylgalactosaminyltransferase 6
chr11_-_80981415 5.90 ENSRNOT00000002499
ENSRNOT00000002496
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr14_-_92495894 5.85 ENSRNOT00000064483
cordon-bleu WH2 repeat protein
chr1_+_65851060 5.63 ENSRNOT00000036880
zinc finger and SCAN domain containing 18
chr1_+_256955652 5.59 ENSRNOT00000020411
leucine-rich, glioma inactivated 1
chrX_-_115175299 5.53 ENSRNOT00000074322
doublecortin
chr9_+_6966908 5.50 ENSRNOT00000072796
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
chr3_-_105470475 5.50 ENSRNOT00000011078
gap junction protein, delta 2
chr10_-_14937336 5.39 ENSRNOT00000025494
SRY box 8
chrX_+_110789269 5.36 ENSRNOT00000086014
ring finger protein 128, E3 ubiquitin protein ligase
chr5_-_79008363 5.36 ENSRNOT00000010040
kinesin family member 12
chr1_-_67206713 5.35 ENSRNOT00000048195
vomeronasal 1 receptor 43
chr2_-_259382765 5.35 ENSRNOT00000091407
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr19_-_56311991 5.33 ENSRNOT00000014090
dysbindin domain containing 1
chr7_+_70452579 5.30 ENSRNOT00000046099
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr8_+_129201669 5.25 ENSRNOT00000025663
ectonucleoside triphosphate diphosphohydrolase 3
chr7_+_29435444 5.23 ENSRNOT00000008613
solute carrier family 5 member 8
chr6_+_27328406 5.19 ENSRNOT00000091159
ENSRNOT00000044278
otoferlin
chr9_+_81615251 5.15 ENSRNOT00000081106
ENSRNOT00000020049
paroxysmal nonkinesigenic dyskinesia
chr11_+_86715981 5.12 ENSRNOT00000050269
catechol-O-methyltransferase
chr2_+_58724855 5.05 ENSRNOT00000089609
calcyphosine-like
chr7_-_116063078 5.02 ENSRNOT00000076932
ENSRNOT00000035496
glycosylphosphatidylinositol anchored molecule like
chr9_-_14618013 4.96 ENSRNOT00000018351
triggering receptor expressed on myeloid cells 2
chr1_+_261158261 4.90 ENSRNOT00000071965
phosphoglycerate mutase 1
chr10_+_89459650 4.88 ENSRNOT00000028149
ENSRNOT00000077942
NBR1, autophagy cargo receptor
chr16_+_39144972 4.84 ENSRNOT00000086728
ADAM metallopeptidase domain 21
chr3_+_97723901 4.84 ENSRNOT00000080416
metallophosphoesterase domain containing 2
chr1_-_72335855 4.82 ENSRNOT00000021613
coiled-coil domain containing 106
chr9_-_45558993 4.76 ENSRNOT00000087866
ENSRNOT00000017714
carbohydrate sulfotransferase 10
chr14_-_3288017 4.72 ENSRNOT00000080452
hypothetical protein LOC689986
chr6_-_111295917 4.71 ENSRNOT00000073428
ENSRNOT00000079373
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr3_+_35271786 4.68 ENSRNOT00000065989
LY6/PLAUR domain containing 6B
chr1_+_164502389 4.67 ENSRNOT00000043554
arrestin, beta 1
chr2_-_186606172 4.60 ENSRNOT00000021938
Fc receptor-like 2
chr4_+_91373942 4.48 ENSRNOT00000043827
coiled-coil serine-rich protein 1
chr7_-_82687130 4.45 ENSRNOT00000006791
transmembrane protein 74
chr1_-_222734184 4.44 ENSRNOT00000049812
ENSRNOT00000028785
reticulon 3
chr18_-_32207749 4.42 ENSRNOT00000090882
ENSRNOT00000018843
Rho GTPase activating protein 26
chr1_-_174119815 4.41 ENSRNOT00000019368
tripartite motif-containing 66
chr10_-_109909646 4.40 ENSRNOT00000074362
ENSRNOT00000088907
dicarbonyl and L-xylulose reductase
chr20_+_9791171 4.40 ENSRNOT00000078031
ATP binding cassette subfamily G member 1
chr14_-_44767120 4.39 ENSRNOT00000003991
WD repeat domain 19
chr8_+_107499262 4.34 ENSRNOT00000081029
centrosomal protein 70
chr6_+_106084815 4.34 ENSRNOT00000058195
signal-induced proliferation-associated 1 like 1
chr19_-_10826895 4.30 ENSRNOT00000090217
ring finger and SPRY domain containing 1
chr1_-_101741441 4.27 ENSRNOT00000028570
sulfotransferase family 2B member 1
chr2_-_154542557 4.25 ENSRNOT00000013392
solute carrier family 33 member 1
chr1_+_53874860 4.25 ENSRNOT00000090486
t-complex-associated testis expressed 2
chr1_+_221801524 4.21 ENSRNOT00000031227
neurexin 2
chr13_+_25656983 4.20 ENSRNOT00000020892
similar to RIKEN cDNA 2310035C23
chr1_+_219764001 4.19 ENSRNOT00000082388
pyruvate carboxylase
chr3_-_60765645 4.19 ENSRNOT00000050513
activating transcription factor 2
chr16_+_39145230 4.16 ENSRNOT00000092942
ADAM metallopeptidase domain 21
chr20_+_13817795 4.08 ENSRNOT00000036518
glutathione S-transferase, theta 3
chr14_+_44479614 4.08 ENSRNOT00000003691
UDP-glucose 6-dehydrogenase
chr17_+_43458553 4.07 ENSRNOT00000088939
solute carrier family 17, member 4
chr14_+_84231639 4.06 ENSRNOT00000066362
galactose-3-O-sulfotransferase 1
chr3_+_80833272 4.06 ENSRNOT00000023583
cholinergic receptor, muscarinic 4
chrX_+_15225645 4.05 ENSRNOT00000008648
glyoxalase domain containing 5
chr10_+_72272248 4.03 ENSRNOT00000003908
carbonic anhydrase 4
chr3_-_52664209 3.99 ENSRNOT00000065126
ENSRNOT00000079020
sodium voltage-gated channel alpha subunit 9
chr4_-_128266082 3.98 ENSRNOT00000039549
nucleoporin 50
chr1_-_67065797 3.91 ENSRNOT00000048152
vomeronasal 1 receptor 46
chr8_-_114853103 3.88 ENSRNOT00000074595
glycerate kinase
chr3_-_64554953 3.74 ENSRNOT00000067452
serine/arginine repetitive matrix protein 1-like
chr8_+_69127708 3.64 ENSRNOT00000013490
small nuclear RNA activating complex, polypeptide 5
chr17_+_69634890 3.64 ENSRNOT00000029049
aldo-keto reductase family 1, member C13
chrX_-_10218583 3.63 ENSRNOT00000013382
nyctalopin
chr14_+_94590765 3.60 ENSRNOT00000072533
similar to similar to RIKEN cDNA 1700001E04
chr5_-_146795866 3.59 ENSRNOT00000065640
toll-like receptor 12
chr18_+_59096643 3.57 ENSRNOT00000025325
WD repeat domain 7
chr17_-_43543172 3.56 ENSRNOT00000080684
ENSRNOT00000029626
ENSRNOT00000082719
solute carrier family 17 member 3
chr6_-_42630983 3.55 ENSRNOT00000071977
ATPase H+ transporting V1 subunit C2
chr5_+_35865605 3.55 ENSRNOT00000011442
cyclin C
chr6_-_108796124 3.48 ENSRNOT00000086545
apoptosis resistant E3 ubiquitin protein ligase 1
chr3_-_146690375 3.47 ENSRNOT00000010641
abhydrolase domain containing 12
chr8_+_132607166 3.47 ENSRNOT00000007223
SAC1 suppressor of actin mutations 1-like (yeast)
chr1_+_263448633 3.42 ENSRNOT00000064510
ectonucleoside triphosphate diphosphohydrolase 7
chrX_+_105911925 3.40 ENSRNOT00000052422
armadillo repeat-containing X-linked protein 1
chr9_+_88918433 3.40 ENSRNOT00000021730
C-C motif chemokine ligand 20
chr5_+_81431600 3.39 ENSRNOT00000013675
tripartite motif-containing 32
chr3_-_46153371 3.31 ENSRNOT00000085885
bromodomain adjacent to zinc finger domain, 2B
chr4_-_49422824 3.25 ENSRNOT00000077889
family with sequence similarity 3, member C
chr2_-_123407496 3.20 ENSRNOT00000080207
transient receptor potential cation channel, subfamily C, member 3
chr13_-_104080631 3.19 ENSRNOT00000032865
lysophospholipase-like 1
chr11_-_38088753 3.19 ENSRNOT00000002713
transmembrane protease, serine 2
chr10_-_14613878 3.17 ENSRNOT00000024072
BAI1-associated protein 3
chr2_+_184243976 3.16 ENSRNOT00000042146
dual endothelin 1, angiotensin II receptor
chr6_-_104409005 3.14 ENSRNOT00000040965
coiled-coil domain containing 177
chr1_-_81144024 3.13 ENSRNOT00000088431
zinc finger protein 94
chr2_+_86914989 3.12 ENSRNOT00000085164
ENSRNOT00000081966
zinc finger protein 457-like
chr14_+_7113544 3.12 ENSRNOT00000038188
hydroxysteroid (17-beta) dehydrogenase 13
chr8_-_115140080 3.11 ENSRNOT00000015851
aminoacylase 1
chr3_-_5802129 3.10 ENSRNOT00000009555
sarcosine dehydrogenase
chr11_-_81639872 3.09 ENSRNOT00000047595
ENSRNOT00000090031
ENSRNOT00000081864
histidine-rich glycoprotein
chr1_+_225037737 3.08 ENSRNOT00000077959
BSCL2, seipin lipid droplet biogenesis associated
chrY_-_1305026 3.07 ENSRNOT00000092901
ubiquitin specific peptidase 9, Y-linked
chr10_-_84881190 3.04 ENSRNOT00000073746
pyridoxamine 5'-phosphate oxidase
chr5_-_133786403 3.03 ENSRNOT00000081051
ENSRNOT00000010318
cytidine/uridine monophosphate kinase 1
chr6_+_9790422 3.03 ENSRNOT00000020959
protein kinase C, epsilon
chr1_+_282640706 3.02 ENSRNOT00000073241
ENSRNOT00000080995
carboxylesterase 2C
chr19_+_15143794 3.00 ENSRNOT00000085762
carboxylesterase 1F
chr18_-_24929091 2.94 ENSRNOT00000019596
protein C
chr17_+_18031228 2.93 ENSRNOT00000081708
thiopurine S-methyltransferase
chr8_-_65587427 2.86 ENSRNOT00000016491
leucine rich repeat containing 49
chr1_-_4011161 2.85 ENSRNOT00000044778
syntaxin binding protein 5
chr18_+_70974885 2.85 ENSRNOT00000025198
similar to cDNA sequence BC031181
chr4_-_150616895 2.84 ENSRNOT00000073562
ankyrin repeat domain 26
chr10_-_15465404 2.84 ENSRNOT00000077826
ENSRNOT00000027593
2,4-dienoyl-CoA reductase 2
chr8_+_49077053 2.82 ENSRNOT00000087922
intraflagellar transport 46
chr8_+_59561721 2.81 ENSRNOT00000093107
ENSRNOT00000065771
ENSRNOT00000088304
cholinergic receptor nicotinic alpha 5 subunit
chr5_+_61425746 2.80 ENSRNOT00000064113
hypothetical LOC298077
chr2_-_9504134 2.79 ENSRNOT00000076996
adhesion G protein-coupled receptor V1
chr1_-_4011511 2.76 ENSRNOT00000040559
syntaxin binding protein 5
chr16_-_45929 2.74 ENSRNOT00000043153

chr6_-_26385761 2.71 ENSRNOT00000073228
glucokinase regulator
chr7_-_123608436 2.70 ENSRNOT00000011880
cytochrome P450, family 2, subfamily d, polypeptide 4
chr4_+_154423209 2.69 ENSRNOT00000075799
alpha-2-macroglobulin-like
chr3_-_7051953 2.62 ENSRNOT00000013473
similar to hypothetical protein MGC29761
chr2_+_264864351 2.57 ENSRNOT00000015434
leucine rich repeat containing 40
chr11_+_60102121 2.57 ENSRNOT00000045521
transmembrane protease, serine 7
chr18_+_40962146 2.54 ENSRNOT00000035656
ADP ribosylation factor like GTPase 14 effector protein like
chr6_+_6946695 2.53 ENSRNOT00000061921
metastasis associated 1 family, member 3
chr18_-_26658892 2.52 ENSRNOT00000038247
erythrocyte membrane protein band 4.1 like 4A
chr14_-_113644779 2.51 ENSRNOT00000005306
cilia and flagella associated protein 36

Network of associatons between targets according to the STRING database.

First level regulatory network of Crx_Gsc

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 17.3 GO:1990743 protein sialylation(GO:1990743)
4.7 14.1 GO:0033058 directional locomotion(GO:0033058)
3.8 11.5 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
3.5 21.3 GO:0006863 purine nucleobase transport(GO:0006863) nucleobase transport(GO:0015851)
3.1 12.2 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
2.6 10.2 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.5 7.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
2.3 22.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
2.2 8.8 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
2.2 13.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
2.2 6.5 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
2.1 18.6 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
1.9 7.6 GO:0015888 thiamine transport(GO:0015888)
1.9 7.6 GO:0072021 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
1.8 12.8 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.7 5.0 GO:0002585 positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) detection of peptidoglycan(GO:0032499)
1.6 7.9 GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.5 4.4 GO:0042732 D-xylose metabolic process(GO:0042732)
1.5 8.8 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
1.4 18.6 GO:0042178 xenobiotic catabolic process(GO:0042178)
1.4 11.4 GO:0090273 regulation of somatostatin secretion(GO:0090273)
1.4 15.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.4 4.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
1.4 4.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.4 18.9 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.3 5.4 GO:0060221 retinal rod cell differentiation(GO:0060221) renal vesicle induction(GO:0072034)
1.3 5.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.3 11.8 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
1.3 18.2 GO:0071420 cellular response to histamine(GO:0071420)
1.3 7.7 GO:0006449 regulation of translational termination(GO:0006449) positive regulation of translational elongation(GO:0045901)
1.2 5.8 GO:0001757 somite specification(GO:0001757)
1.2 4.7 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
1.1 9.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
1.1 6.8 GO:0016080 synaptic vesicle targeting(GO:0016080)
1.1 3.4 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
1.1 4.4 GO:0034436 glycoprotein transport(GO:0034436)
1.1 4.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
1.1 11.7 GO:0007258 JUN phosphorylation(GO:0007258)
1.1 4.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.0 4.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.0 3.1 GO:0097037 heme export(GO:0097037)
1.0 5.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
1.0 3.0 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
1.0 3.0 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
1.0 4.0 GO:0043179 rhythmic excitation(GO:0043179)
1.0 13.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.0 31.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.9 2.8 GO:0046864 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.9 3.5 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.8 2.5 GO:0071613 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.8 4.9 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.8 4.1 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.8 4.1 GO:0035063 nuclear speck organization(GO:0035063)
0.8 3.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.8 3.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.8 10.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.8 2.4 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.8 8.6 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.8 14.0 GO:0001675 acrosome assembly(GO:0001675)
0.8 13.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.8 2.3 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.8 3.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.7 6.7 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.7 4.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.7 10.9 GO:0097503 sialylation(GO:0097503)
0.7 1.4 GO:0072106 regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.7 2.7 GO:0009822 alkaloid catabolic process(GO:0009822)
0.7 2.0 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.6 3.2 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.6 4.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.6 2.5 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.6 1.9 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.6 1.8 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.6 2.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.6 4.3 GO:0000103 sulfate assimilation(GO:0000103)
0.6 11.3 GO:0031643 positive regulation of myelination(GO:0031643)
0.6 2.9 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.6 1.7 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.6 3.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.5 2.7 GO:1903300 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) negative regulation of glucokinase activity(GO:0033132) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) negative regulation of hexokinase activity(GO:1903300)
0.5 8.0 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.5 4.3 GO:0051182 coenzyme transport(GO:0051182)
0.5 1.1 GO:0080144 amino acid homeostasis(GO:0080144)
0.5 5.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.5 3.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.5 5.2 GO:0016082 synaptic vesicle priming(GO:0016082)
0.5 2.4 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.5 7.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.5 15.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.5 7.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.5 2.8 GO:0048496 maintenance of organ identity(GO:0048496)
0.5 2.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.4 8.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.4 13.4 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.4 5.6 GO:0034389 lipid particle organization(GO:0034389)
0.4 1.7 GO:0009597 detection of virus(GO:0009597)
0.4 7.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.4 2.1 GO:0002159 desmosome assembly(GO:0002159)
0.4 2.0 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.4 1.2 GO:0019677 NADP catabolic process(GO:0006742) NAD catabolic process(GO:0019677)
0.4 3.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.4 6.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.4 5.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.4 1.5 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.4 1.1 GO:1900673 olefin metabolic process(GO:1900673)
0.4 1.4 GO:0032824 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.3 2.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.3 1.7 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.3 1.0 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.3 1.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.3 2.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.3 3.6 GO:0015747 urate transport(GO:0015747)
0.3 2.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 2.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.3 3.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 1.2 GO:0030242 pexophagy(GO:0030242)
0.3 1.4 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 2.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.3 1.4 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.3 13.5 GO:0008333 endosome to lysosome transport(GO:0008333)
0.3 4.0 GO:0015701 bicarbonate transport(GO:0015701)
0.3 3.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.3 0.8 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.3 2.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.3 2.5 GO:0016926 protein desumoylation(GO:0016926)
0.2 1.0 GO:0007296 vitellogenesis(GO:0007296)
0.2 9.3 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 14.0 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.2 1.2 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.2 4.1 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.2 4.5 GO:0070831 basement membrane assembly(GO:0070831)
0.2 1.5 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
0.2 1.1 GO:0097070 ductus arteriosus closure(GO:0097070)
0.2 2.8 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 1.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 0.9 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 2.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 11.5 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.2 1.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.2 2.0 GO:0006857 oligopeptide transport(GO:0006857)
0.2 1.4 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509) late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.2 5.4 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.2 0.4 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.2 2.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 1.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 1.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) prolactin signaling pathway(GO:0038161)
0.2 2.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 0.7 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.2 0.7 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 3.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 1.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 14.6 GO:0032091 negative regulation of protein binding(GO:0032091)
0.2 0.9 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.2 1.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 4.8 GO:0007616 long-term memory(GO:0007616)
0.2 1.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 1.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 1.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.0 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.1 1.7 GO:0070863 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 1.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 1.0 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 7.1 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 3.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0014916 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) regulation of lung blood pressure(GO:0014916) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793)
0.1 2.5 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 2.5 GO:0042832 defense response to protozoan(GO:0042832)
0.1 2.1 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 3.6 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 1.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 3.9 GO:0042073 intraciliary transport(GO:0042073)
0.1 1.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.6 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 7.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 1.8 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.5 GO:0050828 regulation of liquid surface tension(GO:0050828)
0.1 4.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 1.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 3.6 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.4 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.1 3.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.5 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 2.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 5.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 2.1 GO:0007099 centriole replication(GO:0007099)
0.1 0.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.6 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 1.0 GO:0048820 hair follicle maturation(GO:0048820)
0.1 2.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.5 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 2.2 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.9 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 6.5 GO:0042552 myelination(GO:0042552)
0.1 1.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.1 0.3 GO:0031620 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.1 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 6.1 GO:0042476 odontogenesis(GO:0042476)
0.1 0.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 5.5 GO:0001508 action potential(GO:0001508)
0.0 1.8 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.7 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 3.6 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 1.8 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 3.8 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 2.6 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.0 2.2 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 12.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.4 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.6 GO:0032418 lysosome localization(GO:0032418)
0.0 0.2 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.6 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:0005960 glycine cleavage complex(GO:0005960)
2.3 9.2 GO:0045298 tubulin complex(GO:0045298)
2.3 6.8 GO:0044317 rod spherule(GO:0044317)
1.9 11.5 GO:0032444 activin responsive factor complex(GO:0032444)
1.9 9.3 GO:0072534 perineuronal net(GO:0072534)
1.5 6.1 GO:0005607 laminin-2 complex(GO:0005607)
1.4 22.6 GO:0005883 neurofilament(GO:0005883)
1.2 14.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.8 5.8 GO:1990357 terminal web(GO:1990357)
0.8 13.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.8 3.1 GO:0061474 phagolysosome membrane(GO:0061474)
0.7 18.6 GO:0043218 compact myelin(GO:0043218)
0.7 3.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.7 5.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.6 4.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.6 1.8 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.6 7.2 GO:0043083 synaptic cleft(GO:0043083)
0.6 13.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.6 1.7 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.6 11.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.6 12.0 GO:0005922 connexon complex(GO:0005922)
0.5 4.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.5 5.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.5 2.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.5 2.0 GO:0002079 inner acrosomal membrane(GO:0002079)
0.5 2.8 GO:1990696 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.5 24.2 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.4 1.3 GO:0071942 XPC complex(GO:0071942)
0.4 1.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 11.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.4 16.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.4 4.7 GO:0031143 pseudopodium(GO:0031143)
0.4 2.2 GO:0089701 U2AF(GO:0089701)
0.4 2.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.3 2.4 GO:0071986 Ragulator complex(GO:0071986)
0.3 4.7 GO:0030897 HOPS complex(GO:0030897)
0.3 13.4 GO:0048786 presynaptic active zone(GO:0048786)
0.3 4.1 GO:0032279 asymmetric synapse(GO:0032279)
0.3 1.8 GO:0044326 chromaffin granule membrane(GO:0042584) dendritic spine neck(GO:0044326)
0.3 3.4 GO:0005859 muscle myosin complex(GO:0005859)
0.3 1.6 GO:0097441 basilar dendrite(GO:0097441)
0.3 7.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 12.3 GO:0045171 intercellular bridge(GO:0045171)
0.3 2.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 1.5 GO:0060205 cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.2 9.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 14.9 GO:0034704 calcium channel complex(GO:0034704)
0.2 4.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 4.9 GO:0031430 M band(GO:0031430)
0.2 4.4 GO:0010369 chromocenter(GO:0010369)
0.2 1.1 GO:0098536 deuterosome(GO:0098536)
0.2 10.1 GO:0031201 SNARE complex(GO:0031201)
0.2 4.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 16.7 GO:0031225 anchored component of membrane(GO:0031225)
0.2 1.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.2 2.5 GO:0008278 cohesin complex(GO:0008278)
0.2 30.7 GO:0043197 dendritic spine(GO:0043197)
0.2 1.3 GO:0042627 chylomicron(GO:0042627)
0.2 1.0 GO:0000125 PCAF complex(GO:0000125) pre-snoRNP complex(GO:0070761)
0.2 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 4.5 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 3.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.9 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.7 GO:0001651 dense fibrillar component(GO:0001651)
0.1 18.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 7.7 GO:0005871 kinesin complex(GO:0005871)
0.1 20.5 GO:0043204 perikaryon(GO:0043204)
0.1 1.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 2.4 GO:0005686 U2 snRNP(GO:0005686)
0.1 15.6 GO:0055037 recycling endosome(GO:0055037)
0.1 2.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 11.0 GO:0036064 ciliary basal body(GO:0036064)
0.1 8.3 GO:0045178 basal part of cell(GO:0045178)
0.1 1.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.0 GO:0042734 presynaptic membrane(GO:0042734)
0.1 9.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 1.1 GO:0005796 Golgi lumen(GO:0005796)
0.1 6.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 16.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 15.0 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 2.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 30.9 GO:0030424 axon(GO:0030424)
0.1 0.4 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 4.8 GO:0005902 microvillus(GO:0005902)
0.1 3.6 GO:0016592 mediator complex(GO:0016592)
0.1 27.6 GO:0000139 Golgi membrane(GO:0000139)
0.1 4.4 GO:0098793 presynapse(GO:0098793)
0.1 0.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 5.8 GO:0005770 late endosome(GO:0005770)
0.1 8.2 GO:0030027 lamellipodium(GO:0030027)
0.1 12.4 GO:0030425 dendrite(GO:0030425)
0.1 3.4 GO:0005811 lipid particle(GO:0005811)
0.1 2.3 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 2.8 GO:0005884 actin filament(GO:0005884)
0.1 4.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 17.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 5.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.8 GO:0019013 viral nucleocapsid(GO:0019013)
0.0 2.1 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.3 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 3.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 7.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 7.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 1.3 GO:0005643 nuclear pore(GO:0005643)
0.0 2.5 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.1 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 2.7 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.8 GO:0045202 synapse(GO:0045202)
0.0 1.0 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.9 GO:0005874 microtubule(GO:0005874)
0.0 4.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.0 GO:0001565 phorbol ester receptor activity(GO:0001565)
3.9 11.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
3.8 11.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
3.7 18.3 GO:1904315 benzodiazepine receptor activity(GO:0008503) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
2.8 11.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
2.3 9.2 GO:0099609 microtubule lateral binding(GO:0099609)
2.3 11.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
2.2 15.4 GO:0004111 creatine kinase activity(GO:0004111)
2.0 13.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.8 21.3 GO:0015216 purine nucleotide transmembrane transporter activity(GO:0015216)
1.8 14.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
1.6 6.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.6 4.7 GO:0031762 follicle-stimulating hormone receptor binding(GO:0031762) vasopressin receptor binding(GO:0031893)
1.5 18.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.5 4.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041) glycoprotein transporter activity(GO:0034437)
1.4 17.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
1.4 4.3 GO:0050294 steroid sulfotransferase activity(GO:0050294)
1.4 4.3 GO:0051185 coenzyme transporter activity(GO:0051185)
1.4 4.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
1.2 4.9 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.2 11.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.2 3.5 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.1 5.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.0 3.1 GO:0004046 aminoacylase activity(GO:0004046)
1.0 5.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
1.0 12.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
1.0 4.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
1.0 3.0 GO:0009041 uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
1.0 17.9 GO:0043295 glutathione binding(GO:0043295)
1.0 5.0 GO:0070891 lipoteichoic acid binding(GO:0070891)
1.0 2.9 GO:0070012 oligopeptidase activity(GO:0070012)
0.9 18.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.8 13.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.8 4.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.8 2.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.8 2.3 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.8 3.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.8 3.0 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
0.7 10.5 GO:0016594 glycine binding(GO:0016594)
0.7 9.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.7 8.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.7 2.8 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.7 2.7 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.7 11.5 GO:0070410 co-SMAD binding(GO:0070410)
0.7 12.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.7 15.1 GO:0032183 SUMO binding(GO:0032183)
0.6 7.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.6 3.2 GO:0004945 angiotensin type II receptor activity(GO:0004945) endothelin receptor activity(GO:0004962)
0.6 5.0 GO:0008172 S-methyltransferase activity(GO:0008172)
0.6 4.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.6 1.7 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.6 6.8 GO:0019864 IgG binding(GO:0019864)
0.6 1.7 GO:0004925 prolactin receptor activity(GO:0004925)
0.5 5.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5 15.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 2.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.5 2.5 GO:0035473 lipase binding(GO:0035473)
0.5 2.4 GO:0004969 histamine receptor activity(GO:0004969)
0.5 1.4 GO:0008458 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
0.5 1.4 GO:0070573 metallodipeptidase activity(GO:0070573)
0.5 2.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.4 7.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.4 1.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.4 1.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 1.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.4 5.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.4 1.7 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.4 2.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.4 3.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 2.7 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.4 6.8 GO:0005522 profilin binding(GO:0005522)
0.4 1.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.3 5.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.3 2.0 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.3 5.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.3 17.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 1.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 29.3 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.3 0.9 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 4.2 GO:0035497 cAMP response element binding(GO:0035497)
0.3 2.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.3 1.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.3 3.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 8.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 5.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.2 1.0 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.2 1.4 GO:0004568 chitinase activity(GO:0004568)
0.2 3.1 GO:0005542 folic acid binding(GO:0005542)
0.2 0.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 3.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 6.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 3.4 GO:0015464 acetylcholine receptor activity(GO:0015464) acetylcholine-gated cation channel activity(GO:0022848)
0.2 1.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 2.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 1.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 3.1 GO:0019865 immunoglobulin binding(GO:0019865)
0.2 2.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.2 4.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 1.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.2 4.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 1.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 1.8 GO:0070492 oligosaccharide binding(GO:0070492)
0.2 3.0 GO:0010181 FMN binding(GO:0010181)
0.1 4.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.1 4.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.0 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 4.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 5.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 17.7 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.1 4.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 4.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 3.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 3.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 14.4 GO:0044325 ion channel binding(GO:0044325)
0.1 2.0 GO:0001848 complement binding(GO:0001848)
0.1 2.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 9.3 GO:0005178 integrin binding(GO:0005178)
0.1 5.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 4.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 3.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.5 GO:0005123 death receptor binding(GO:0005123)
0.1 9.8 GO:0001948 glycoprotein binding(GO:0001948)
0.1 2.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 19.6 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.1 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 25.5 GO:0005525 GTP binding(GO:0005525)
0.1 0.4 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 17.1 GO:0008017 microtubule binding(GO:0008017)
0.1 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0036122 BMP binding(GO:0036122)
0.1 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 1.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 1.0 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 1.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 2.4 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 2.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.3 GO:0005496 steroid binding(GO:0005496)
0.0 1.5 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.3 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.5 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 14.4 ST GA12 PATHWAY G alpha 12 Pathway
0.4 11.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.4 14.1 PID REELIN PATHWAY Reelin signaling pathway
0.4 7.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.4 14.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.4 9.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.4 6.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 14.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 27.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 5.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 7.2 PID IL1 PATHWAY IL1-mediated signaling events
0.2 7.5 PID ATR PATHWAY ATR signaling pathway
0.1 1.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 8.3 PID NOTCH PATHWAY Notch signaling pathway
0.1 8.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 8.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 3.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.4 PID ARF 3PATHWAY Arf1 pathway
0.1 2.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.0 PID MYC PATHWAY C-MYC pathway
0.1 2.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 2.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 10.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 20.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
1.1 18.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.0 15.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.9 12.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.8 23.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.8 14.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.7 19.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.6 18.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.6 8.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.6 10.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.5 12.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.5 11.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.5 6.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.5 7.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.5 11.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.5 12.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.5 18.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.5 8.6 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.5 10.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.4 14.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.4 7.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.4 6.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 10.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.4 12.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 6.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 9.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 5.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.3 6.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.3 3.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 5.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.3 2.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 1.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 2.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 5.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.2 3.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 5.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 3.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 4.7 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.2 23.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 3.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 2.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.3 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 4.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 3.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 6.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 4.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 5.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.4 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 1.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 4.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 1.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 4.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 3.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 3.5 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 2.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases