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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Crem_Jdp2

Z-value: 1.10

Motif logo

Transcription factors associated with Crem_Jdp2

Gene Symbol Gene ID Gene Info
ENSRNOG00000014900 cAMP responsive element modulator
ENSRNOG00000008224 Jun dimerization protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cremrn6_v1_chr17_+_57031766_57031766-0.564.6e-28Click!
Jdp2rn6_v1_chr6_+_109466060_1094660600.394.1e-13Click!

Activity profile of Crem_Jdp2 motif

Sorted Z-values of Crem_Jdp2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_189629297 72.70 ENSRNOT00000049810
DENN domain containing 4B
chr1_-_220467159 61.52 ENSRNOT00000075365
transmembrane protein 151A
chr1_+_177495782 55.28 ENSRNOT00000021020
TEA domain transcription factor 1
chr1_+_162768156 54.82 ENSRNOT00000049321
p21 (RAC1) activated kinase 1
chr11_-_62451149 53.68 ENSRNOT00000093686
ENSRNOT00000081443
zinc finger and BTB domain containing 20
chr9_-_78969013 50.71 ENSRNOT00000019772
ENSRNOT00000057585
fibronectin 1
chr17_+_10463303 49.13 ENSRNOT00000060822
ring finger protein 44
chr3_+_125428260 49.08 ENSRNOT00000028892
chromogranin B
chr16_+_72401887 47.67 ENSRNOT00000074449
uncharacterized LOC100910163
chr16_+_72388880 43.72 ENSRNOT00000072459
similar to Protein C8orf4 (Thyroid cancer protein 1) (TC-1)
chr10_+_16970626 42.81 ENSRNOT00000005383
dual specificity phosphatase 1
chr4_-_57625147 39.02 ENSRNOT00000074649
ENSRNOT00000078961
ubiquitin-conjugating enzyme E2H
chr5_+_159845774 38.78 ENSRNOT00000012328
Eph receptor A2
chr1_+_81395841 38.10 ENSRNOT00000072750
immunity-related GTPase Q
chr10_-_65424802 36.82 ENSRNOT00000018468
Tnf receptor associated factor 4
chr18_-_28017925 35.77 ENSRNOT00000075420
leucine rich repeat transmembrane neuronal 2
chr9_-_43276685 34.11 ENSRNOT00000022779
ARP1 actin-related protein 1 homolog B, centractin beta
chr10_+_11724032 33.72 ENSRNOT00000008966
TNF receptor-associated protein 1
chr9_-_85243001 32.42 ENSRNOT00000020219
secretogranin II
chr13_-_50916982 32.25 ENSRNOT00000004408
BTG anti-proliferation factor 2
chr16_-_50501921 30.76 ENSRNOT00000081023
FAT atypical cadherin 1
chr16_-_50501716 30.50 ENSRNOT00000067486
FAT atypical cadherin 1
chr16_-_74122889 30.46 ENSRNOT00000025763
plasminogen activator, tissue type
chr12_-_13668515 30.38 ENSRNOT00000086847
fascin actin-bundling protein 1
chr12_+_47920743 29.96 ENSRNOT00000072511
methylmalonic aciduria (cobalamin deficiency) cblB type
chr6_+_129399468 27.22 ENSRNOT00000071735
ENSRNOT00000074621
bradykinin receptor B2
chr4_-_157078130 26.82 ENSRNOT00000015570
calsyntenin 3
chr20_-_10257044 25.85 ENSRNOT00000068289
WD repeat domain 4
chr17_+_31493107 24.67 ENSRNOT00000023611
ENSRNOT00000086264
tubulin, beta 2A class IIa
chr12_+_17416327 24.58 ENSRNOT00000089590
ENSRNOT00000092186
ArfGAP with dual PH domains 1
chr15_+_43007908 24.06 ENSRNOT00000084753
ENSRNOT00000091567
ENSRNOT00000087709
stathmin 4
chr9_+_82370924 23.98 ENSRNOT00000025219
zinc finger AN1-type containing 2B
chrX_+_151103576 23.87 ENSRNOT00000015401
SLIT and NTRK-like family, member 2
chr10_-_64398294 23.71 ENSRNOT00000010386
glyoxalase domain containing 4
chr3_+_8802852 23.16 ENSRNOT00000033934
leucine rich repeat containing 8 family, member A
chr8_+_69127708 22.80 ENSRNOT00000013490
small nuclear RNA activating complex, polypeptide 5
chr15_+_57290849 22.51 ENSRNOT00000014909
carboxypeptidase B2
chr6_+_126434226 22.31 ENSRNOT00000090857
chromogranin A
chr1_+_157573324 22.31 ENSRNOT00000092066
RAB30, member RAS oncogene family
chr3_-_120011364 22.25 ENSRNOT00000018922
fumarylacetoacetate hydrolase domain containing 2A
chr2_-_185005572 22.04 ENSRNOT00000093291
family with sequence similarity 160, member A1
chr8_-_57255263 21.59 ENSRNOT00000028972
hypothetical protein LOC100125362
chr10_+_102136283 21.42 ENSRNOT00000003735
somatostatin receptor 2
chrX_+_1321315 21.23 ENSRNOT00000014250
synapsin I
chr4_+_163293724 21.19 ENSRNOT00000077356
GABA type A receptor associated protein like 1
chr19_-_43841795 21.03 ENSRNOT00000079539
lactate dehydrogenase D
chr8_+_44136496 20.77 ENSRNOT00000087022
sodium voltage-gated channel beta subunit 3
chr11_-_38457373 20.77 ENSRNOT00000041177
zinc finger protein 295
chr17_+_57074525 20.33 ENSRNOT00000020012
ENSRNOT00000074146
cAMP responsive element modulator
chr2_-_187909394 20.19 ENSRNOT00000032355
RAB25, member RAS oncogene family
chr20_-_10680283 19.79 ENSRNOT00000001579
salt-inducible kinase 1
chrX_+_16170576 19.57 ENSRNOT00000003895
chloride voltage-gated channel 5
chr15_-_109394905 19.27 ENSRNOT00000019602
ENSRNOT00000078424
transmembrane and tetratricopeptide repeat containing 4
chr5_-_114014277 18.58 ENSRNOT00000011731
Jun proto-oncogene, AP-1 transcription factor subunit
chr10_-_37554664 18.58 ENSRNOT00000007621
protein phosphatase 2 catalytic subunit alpha
chr9_-_19613360 18.44 ENSRNOT00000029593
regulator of calcineurin 2
chr1_-_89124132 18.36 ENSRNOT00000031044
HAUS augmin-like complex, subunit 5
chr6_+_72891725 18.35 ENSRNOT00000038074
nucleotide binding protein-like
chr4_-_64981384 17.97 ENSRNOT00000017338
cAMP responsive element binding protein 3-like 2
chr2_-_66608324 17.53 ENSRNOT00000077597
ceroid-lipofuscinosis, neuronal 5
chr7_-_124982566 17.52 ENSRNOT00000075099
sulfotransferase family 4A, member 1
chr12_+_37984790 17.36 ENSRNOT00000001445
VPS37B, ESCRT-I subunit
chr4_+_157554794 16.83 ENSRNOT00000024116
inhibitor of growth family, member 4
chr1_+_196996581 16.81 ENSRNOT00000021690
interleukin 21 receptor
chr10_-_45514878 16.73 ENSRNOT00000036940
IBA57 homolog, iron-sulfur cluster assembly
chr8_-_50246656 16.43 ENSRNOT00000024240
SID1 transmembrane family, member 2
chr6_-_91456696 16.36 ENSRNOT00000005577
ribosomal protein S29
chr1_+_103172987 16.29 ENSRNOT00000018688
transmembrane protein 86A
chr4_+_157452607 16.27 ENSRNOT00000022467
myeloid leukemia factor 2
chr19_-_37990353 16.24 ENSRNOT00000026817
DEAD-box helicase 28
chr4_+_157453069 16.12 ENSRNOT00000088622
myeloid leukemia factor 2
chr8_+_114866768 16.10 ENSRNOT00000076731
WD repeat domain 82
chr3_+_150801289 16.10 ENSRNOT00000035060
microtubule-associated protein 1 light chain 3 alpha
chr2_+_188784222 16.07 ENSRNOT00000028095
phosphomevalonate kinase
chr17_-_47394231 16.05 ENSRNOT00000079368
ENSRNOT00000079216
secreted frizzled-related protein 4
chr10_-_14056169 16.04 ENSRNOT00000017833
synaptogyrin 3
chrX_+_158978755 15.92 ENSRNOT00000066809
solute carrier family 9 member A6
chr8_+_22021213 15.77 ENSRNOT00000049706
mitochondrial ribosomal protein L4
chr2_+_181331464 15.71 ENSRNOT00000017448
microtubule-associated protein 9
chr9_+_30939555 15.69 ENSRNOT00000016887
LMBR1 domain containing 1
chr6_+_43829945 15.61 ENSRNOT00000086548
Kruppel-like factor 11
chr8_-_50245838 15.53 ENSRNOT00000035310
SID1 transmembrane family, member 2
chr5_+_148320438 15.42 ENSRNOT00000018742
penta-EF hand domain containing 1
chr4_-_113866674 15.40 ENSRNOT00000010020
docking protein 1
chrX_-_158978995 15.40 ENSRNOT00000001179
membrane magnesium transporter 1
chr5_-_152464850 15.23 ENSRNOT00000021937
zinc finger protein 593
chr8_-_128009951 14.86 ENSRNOT00000018056
oxidative-stress responsive 1
chr8_+_117793289 14.82 ENSRNOT00000056199
shisa family member 5
chr4_-_6330699 14.62 ENSRNOT00000078077
ENSRNOT00000011814
polypeptide N-acetylgalactosaminyltransferase 11
chr19_+_31524671 14.53 ENSRNOT00000024616
Hedgehog-interacting protein
chr17_-_9695292 14.40 ENSRNOT00000036162
proline rich 7 (synaptic)
chr7_+_63922879 14.40 ENSRNOT00000043581
similar to Hypothetical protein LOC270802
chr1_-_59732409 14.28 ENSRNOT00000014824
hyaluronan synthase 1
chrX_+_45420596 14.27 ENSRNOT00000051897
steroid sulfatase (microsomal), isozyme S
chr1_-_198382614 13.92 ENSRNOT00000055016
aspartate beta-hydroxylase domain containing 1
chr8_+_122076759 13.76 ENSRNOT00000012545
cytoplasmic linker associated protein 2
chr14_-_83062302 13.59 ENSRNOT00000086769
ENSRNOT00000085735
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chrX_+_28593405 13.46 ENSRNOT00000071708
thymosin beta 4, X-linked
chr4_+_113866804 13.39 ENSRNOT00000081196
lysyl oxidase-like 3
chr10_-_13542077 13.36 ENSRNOT00000008736
ATPase H+ transporting V0 subunit C
chr1_+_261415191 13.26 ENSRNOT00000083287
ENSRNOT00000040740
zinc finger FYVE-type containing 27
chr5_+_36076565 13.26 ENSRNOT00000013599
failed axon connections homolog
chr1_-_64090017 13.10 ENSRNOT00000086622
ENSRNOT00000091654
ribosomal protein S9
chr7_-_118332577 13.01 ENSRNOT00000090370
RNA binding protein, fox-1 homolog 2
chr4_+_83391283 12.98 ENSRNOT00000031365
cAMP responsive element binding protein 5
chr18_-_51651267 12.97 ENSRNOT00000020325
aldehyde dehydrogenase 7 family, member A1
chr7_+_121311024 12.87 ENSRNOT00000092260
ENSRNOT00000023066
ENSRNOT00000081377
synaptogyrin 1
chr14_+_63095720 12.75 ENSRNOT00000006071
PPARG coactivator 1 alpha
chr14_-_80355420 12.74 ENSRNOT00000049798
acyl-CoA oxidase 3, pristanoyl
chrX_-_1346181 12.73 ENSRNOT00000042736
60S ribosomal protein L12-like
chr14_-_83741969 12.73 ENSRNOT00000026293
inositol polyphosphate-5-phosphatase J
chr1_+_213870502 12.67 ENSRNOT00000086483
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr7_-_14435967 12.64 ENSRNOT00000074801
peptidoglycan recognition protein 2
chr10_+_56576428 12.49 ENSRNOT00000079237
ENSRNOT00000023291
claudin 7
chr2_-_152824547 12.37 ENSRNOT00000019824
DEAH-box helicase 36
chr17_+_57075218 12.31 ENSRNOT00000089536
cAMP responsive element modulator
chr10_+_104582955 12.29 ENSRNOT00000009733
unkempt family zinc finger
chr12_+_13102019 12.21 ENSRNOT00000092628
ras-related C3 botulinum toxin substrate 1
chr8_-_62248013 12.20 ENSRNOT00000080012
ENSRNOT00000089602
secretory carrier membrane protein 5
chrX_+_15064594 12.16 ENSRNOT00000007130
TBC1 domain family, member 25
chr8_+_48472824 12.01 ENSRNOT00000010463
ENSRNOT00000090780
melanoma cell adhesion molecule
chr7_-_58587787 11.86 ENSRNOT00000005814
leucine rich repeat containing G protein coupled receptor 5
chr10_+_37757146 11.76 ENSRNOT00000008119
ENSRNOT00000087555
similar to HTGN29 protein; keratinocytes associated transmembrane protein 2
chr6_-_7741414 11.70 ENSRNOT00000038246
THADA, armadillo repeat containing
chr4_-_168297373 11.67 ENSRNOT00000066575
LDL receptor related protein 6
chr10_+_45559578 11.63 ENSRNOT00000004011
similar to RIKEN cDNA 2310033P09
chr7_+_12948952 11.42 ENSRNOT00000010714
SHC adaptor protein 2
chr9_+_45672157 11.15 ENSRNOT00000017882
phosducin-like 3
chr19_+_56272162 11.02 ENSRNOT00000030399
AFG3(ATPase family gene 3)-like 1 (S. cerevisiae)
chr1_+_225048149 10.98 ENSRNOT00000036454
LRRN4 C-terminal like
chrX_-_157139291 10.96 ENSRNOT00000092123
solute carrier family 6 member 8
chr3_-_15463881 10.91 ENSRNOT00000009706
RNA binding motif protein 18
chr8_+_114867062 10.90 ENSRNOT00000074771
WD repeat domain 82
chr9_+_82674202 10.88 ENSRNOT00000027208
transmembrane protein 198
chr1_-_64021321 10.87 ENSRNOT00000090819
ribosomal protein S9
chr4_+_6330466 10.82 ENSRNOT00000089582
RIKEN cDNA E130116L18 gene
chr3_+_100366168 10.82 ENSRNOT00000006689
kinesin family member 18A
chr1_+_201256910 10.76 ENSRNOT00000090143
transforming, acidic coiled-coil containing protein 2
chr9_-_99651813 10.67 ENSRNOT00000022089
NADH:ubiquinone oxidoreductase subunit A10
chr3_+_161212156 10.64 ENSRNOT00000020280
ENSRNOT00000083553
deoxynucleotidyltransferase, terminal, interacting protein 1
chr7_-_142180997 10.63 ENSRNOT00000087632
transcription factor CP2
chr7_+_25919867 10.58 ENSRNOT00000009625
ENSRNOT00000090153
RIC8 guanine nucleotide exchange factor B
chr12_-_16002788 10.56 ENSRNOT00000090318
archaelysin family metallopeptidase 1
chr1_-_31055453 10.42 ENSRNOT00000031083
SOGA family member 3
chr11_+_80358211 10.35 ENSRNOT00000002519
somatostatin
chr1_-_182140570 10.33 ENSRNOT00000060098
YTH domain containing 2
chr1_-_216080287 10.31 ENSRNOT00000027682
tyrosine hydroxylase
chr14_-_78707861 10.24 ENSRNOT00000091927
protein phosphatase 2, regulatory subunit B, gamma
chr1_-_252808380 10.24 ENSRNOT00000025856
cholesterol 25-hydroxylase
chr3_+_140024043 10.22 ENSRNOT00000086409
Ras and Rab interactor 2
chr19_+_37990374 10.14 ENSRNOT00000026827
dihydrouridine synthase 2
chr10_+_70884531 10.14 ENSRNOT00000015199
C-C motif chemokine ligand 4
chr10_+_64398339 10.13 ENSRNOT00000056278
mitochondrial rRNA methyltransferase 3
chr10_+_13000090 10.04 ENSRNOT00000004845
claudin 6
chr1_+_219329574 10.04 ENSRNOT00000071109
calcium binding protein 2
chr18_-_16497886 9.96 ENSRNOT00000021624
regulation of nuclear pre-mRNA domain containing 1A
chr9_-_19476646 9.90 ENSRNOT00000013703
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr19_-_54245855 9.74 ENSRNOT00000023855
ER membrane protein complex subunit 8
chr1_-_156296161 9.66 ENSRNOT00000025653
CREB/ATF bZIP transcription factor
chr4_-_159079003 9.66 ENSRNOT00000026691
potassium voltage-gated channel subfamily A member 5
chr13_+_110257571 9.65 ENSRNOT00000005715
integrator complex subunit 7
chr7_-_2909144 9.65 ENSRNOT00000082518
ENSRNOT00000089074
ENSRNOT00000085644
myosin light chain 6
chr7_+_141054494 9.60 ENSRNOT00000088176
transmembrane BAX inhibitor motif containing 6
chr6_+_26387877 9.55 ENSRNOT00000076105

chr7_-_2941122 9.50 ENSRNOT00000082107
extended synaptotagmin 1
chr1_-_80221710 9.41 ENSRNOT00000091687
FosB proto-oncogene, AP-1 transcription factor subunit
chr3_+_110442637 9.38 ENSRNOT00000010471
p21 (RAC1) activated kinase 6
chr18_-_77322690 9.36 ENSRNOT00000058382
nuclear factor of activated T-cells 1
chr12_+_9034308 9.36 ENSRNOT00000001248
FMS-related tyrosine kinase 1
chr8_+_50310405 9.29 ENSRNOT00000073507
SIK family kinase 3
chr4_-_67520356 9.29 ENSRNOT00000014604
B-Raf proto-oncogene, serine/threonine kinase
chr7_-_142180794 9.21 ENSRNOT00000037447
transcription factor CP2
chr15_-_43733182 9.19 ENSRNOT00000015318
protein phosphatase 2, regulatory subunit B, alpha
chr10_-_108150511 9.18 ENSRNOT00000073337
chromobox 8
chr19_-_25955371 9.11 ENSRNOT00000004042
ENSRNOT00000084123
RAD23 homolog A, nucleotide excision repair protein
chr3_+_137618898 9.04 ENSRNOT00000007249
proprotein convertase subtilisin/kexin type 2
chr9_+_10428853 9.03 ENSRNOT00000074253
lon peptidase 1, mitochondrial
chr7_-_44121130 8.91 ENSRNOT00000005706
neurotensin
chr9_+_17817721 8.90 ENSRNOT00000086986
ENSRNOT00000026920
heat shock protein 90 alpha family class B member 1
chrX_-_82986051 8.89 ENSRNOT00000077587
highly divergent homeobox
chr4_-_51946715 8.83 ENSRNOT00000079130
protection of telomeres 1
chr8_-_50228369 8.82 ENSRNOT00000024030
transgelin
chr10_+_37594578 8.76 ENSRNOT00000007676
S-phase kinase-associated protein 1
chr7_+_144577465 8.67 ENSRNOT00000021647
homeo box C10
chr4_-_113886994 8.64 ENSRNOT00000037333
HtrA serine peptidase 2
chr6_-_60151420 8.50 ENSRNOT00000073910
interferon-related developmental regulator 1
chr1_-_80666566 8.41 ENSRNOT00000082125
ENSRNOT00000025388
nectin cell adhesion molecule 2
chr3_-_72052990 8.37 ENSRNOT00000064009
ENSRNOT00000081400
catenin delta 1
chr7_-_75597276 8.24 ENSRNOT00000035628
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr6_-_42473738 8.14 ENSRNOT00000033327
potassium voltage-gated channel modifier subfamily F member 1
chr1_+_280423079 8.09 ENSRNOT00000011983
solute carrier family 18 member A2
chr3_+_15463953 8.07 ENSRNOT00000033047
mitochondrial ribosome recycling factor
chr19_-_34105610 7.99 ENSRNOT00000017347
protein arginine methyltransferase 9
chr1_+_73719005 7.97 ENSRNOT00000025110
CDC42 effector protein 5
chr9_+_78968814 7.97 ENSRNOT00000057584

chr1_-_178218761 7.95 ENSRNOT00000019199
parathyroid hormone
chr14_-_86868598 7.91 ENSRNOT00000087212
NAC alpha domain containing
chr7_-_18612118 7.87 ENSRNOT00000078122
ENSRNOT00000010197
RAB11B, member RAS oncogene family
chr3_+_148635775 7.83 ENSRNOT00000067261
transmembrane 9 superfamily member 4
chr10_-_90410569 7.82 ENSRNOT00000036112
integrin subunit alpha 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of Crem_Jdp2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
16.9 50.7 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161) interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) regulation of transforming growth factor-beta secretion(GO:2001201)
13.7 54.8 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
12.8 12.8 GO:1903210 glomerular visceral epithelial cell apoptotic process(GO:1903210)
11.2 33.7 GO:1901856 negative regulation of cellular respiration(GO:1901856)
10.4 72.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
9.7 38.8 GO:0048319 notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319) negative regulation of lymphangiogenesis(GO:1901491)
7.9 47.7 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
7.6 30.5 GO:0060279 positive regulation of ovulation(GO:0060279)
7.5 22.5 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
7.4 22.3 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
7.0 7.0 GO:0060701 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
6.8 27.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
6.5 25.8 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
6.0 24.0 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
6.0 24.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
5.8 11.7 GO:0061354 planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
5.8 17.4 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
5.4 16.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
5.4 16.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
5.3 32.0 GO:0033227 dsRNA transport(GO:0033227)
5.1 15.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
5.0 64.6 GO:0014883 transition between fast and slow fiber(GO:0014883)
5.0 14.9 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
4.6 41.3 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
4.5 13.6 GO:0006713 glucocorticoid catabolic process(GO:0006713)
4.5 35.8 GO:0002091 negative regulation of receptor internalization(GO:0002091)
4.5 13.4 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
4.3 30.4 GO:0071460 microspike assembly(GO:0030035) cellular response to cell-matrix adhesion(GO:0071460)
4.2 12.7 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
4.1 12.4 GO:0090669 telomerase RNA stabilization(GO:0090669)
4.1 16.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
4.0 11.9 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
3.9 30.9 GO:0007042 lysosomal lumen acidification(GO:0007042)
3.7 36.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
3.6 21.7 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
3.6 14.3 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
3.6 21.4 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
3.4 10.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
3.2 28.7 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
3.2 12.6 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
3.1 15.5 GO:0090168 Golgi reassembly(GO:0090168)
3.1 18.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
3.1 42.8 GO:0090231 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
3.0 12.2 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
3.0 20.8 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
3.0 8.9 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
2.9 8.8 GO:0060383 positive regulation of DNA strand elongation(GO:0060383)
2.9 14.6 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
2.8 8.4 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
2.7 26.8 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
2.6 7.9 GO:0045054 constitutive secretory pathway(GO:0045054)
2.6 23.2 GO:0002329 pre-B cell differentiation(GO:0002329)
2.6 7.7 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
2.5 30.2 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
2.4 12.2 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
2.4 16.7 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
2.4 7.1 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982) positive regulation of glycogen catabolic process(GO:0045819)
2.3 9.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
2.3 32.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
2.2 15.4 GO:0006824 cobalt ion transport(GO:0006824)
2.1 6.4 GO:0090135 submandibular salivary gland formation(GO:0060661) positive regulation of hair follicle cell proliferation(GO:0071338) actin filament branching(GO:0090135)
2.0 10.1 GO:0071314 cellular response to cocaine(GO:0071314)
2.0 10.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
2.0 8.0 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.9 5.8 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
1.9 7.8 GO:0021571 rhombomere 5 development(GO:0021571)
1.9 19.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.9 21.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
1.9 7.7 GO:0061084 negative regulation of protein refolding(GO:0061084)
1.9 13.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
1.9 5.7 GO:0031587 lactate biosynthetic process from pyruvate(GO:0019244) positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) regulation of intracellular mRNA localization(GO:1904580)
1.9 13.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.9 53.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.8 5.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.8 9.0 GO:0030070 insulin processing(GO:0030070)
1.8 8.9 GO:0097332 response to antipsychotic drug(GO:0097332)
1.8 12.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.7 7.0 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
1.7 5.2 GO:0036451 cap mRNA methylation(GO:0036451)
1.7 10.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
1.7 3.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.7 8.4 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
1.6 13.0 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
1.6 43.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
1.6 9.7 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
1.6 6.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
1.6 11.2 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.6 28.2 GO:0031268 pseudopodium organization(GO:0031268)
1.6 9.4 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
1.5 10.8 GO:0030953 astral microtubule organization(GO:0030953)
1.5 16.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
1.5 4.4 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
1.4 8.6 GO:1904923 regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
1.4 5.8 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.4 7.2 GO:0016584 nucleosome positioning(GO:0016584)
1.4 4.2 GO:0044375 regulation of peroxisome size(GO:0044375)
1.4 11.0 GO:0015871 choline transport(GO:0015871)
1.4 61.3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
1.4 27.0 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
1.3 5.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.3 18.4 GO:0007614 short-term memory(GO:0007614)
1.3 3.8 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.2 15.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.2 12.0 GO:0061042 vascular wound healing(GO:0061042)
1.2 15.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
1.2 22.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
1.1 22.8 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.1 6.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.1 10.2 GO:0035754 B cell chemotaxis(GO:0035754)
1.1 12.5 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
1.1 5.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
1.1 14.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
1.1 12.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
1.1 4.4 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
1.1 16.1 GO:0010040 response to iron(II) ion(GO:0010040)
1.0 3.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
1.0 11.0 GO:0034982 mitochondrial protein processing(GO:0034982)
1.0 9.7 GO:0034472 snRNA 3'-end processing(GO:0034472)
1.0 6.7 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.9 10.3 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.9 8.1 GO:0032790 ribosome disassembly(GO:0032790)
0.9 13.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.9 3.5 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.9 5.2 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.8 6.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.8 15.7 GO:0046325 negative regulation of glucose import(GO:0046325)
0.8 7.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.8 32.1 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.8 7.0 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.8 3.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.8 16.7 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.8 12.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.7 12.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.7 28.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.7 6.3 GO:0015866 ADP transport(GO:0015866)
0.7 9.0 GO:0010044 response to aluminum ion(GO:0010044)
0.7 4.8 GO:0042256 mature ribosome assembly(GO:0042256) bone marrow development(GO:0048539)
0.7 35.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.7 7.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.6 1.9 GO:0021627 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.6 5.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.6 3.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.6 10.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.6 12.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.5 12.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.5 1.6 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.5 7.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.5 5.0 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.5 19.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.5 5.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.5 14.5 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.5 24.6 GO:0009268 response to pH(GO:0009268)
0.5 1.4 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.5 6.1 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.5 10.6 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.4 21.5 GO:0021762 substantia nigra development(GO:0021762)
0.4 37.6 GO:0051225 spindle assembly(GO:0051225)
0.4 2.0 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 5.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.4 9.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.4 8.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.4 21.9 GO:0043278 response to morphine(GO:0043278)
0.4 3.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 1.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.4 2.2 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.4 6.5 GO:0021542 dentate gyrus development(GO:0021542)
0.4 12.2 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.4 5.3 GO:0060746 parental behavior(GO:0060746)
0.4 1.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.3 5.2 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.3 24.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 18.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.3 4.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.3 16.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.3 5.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.3 4.7 GO:0003094 glomerular filtration(GO:0003094)
0.3 8.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.3 9.3 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.3 6.5 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.3 2.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.3 2.6 GO:0055064 chloride ion homeostasis(GO:0055064)
0.3 2.0 GO:0003360 brainstem development(GO:0003360)
0.3 3.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.3 3.0 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.3 2.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 13.0 GO:0060612 adipose tissue development(GO:0060612)
0.2 8.5 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.2 5.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 2.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 10.1 GO:0001510 RNA methylation(GO:0001510)
0.2 4.3 GO:0033327 estrogen metabolic process(GO:0008210) Leydig cell differentiation(GO:0033327)
0.2 4.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.2 0.6 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.2 8.3 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.2 19.4 GO:0007030 Golgi organization(GO:0007030)
0.2 16.3 GO:0000187 activation of MAPK activity(GO:0000187)
0.2 2.6 GO:0002076 osteoblast development(GO:0002076)
0.2 6.4 GO:0042572 retinol metabolic process(GO:0042572)
0.2 2.3 GO:0006105 succinate metabolic process(GO:0006105)
0.1 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 7.8 GO:0070527 platelet aggregation(GO:0070527)
0.1 10.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 0.3 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.4 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 31.6 GO:0006914 autophagy(GO:0006914)
0.1 1.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 4.9 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 2.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 9.7 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.1 26.6 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.1 9.4 GO:0007613 memory(GO:0007613)
0.1 5.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 2.6 GO:0060711 anterior/posterior axis specification(GO:0009948) labyrinthine layer development(GO:0060711)
0.1 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 4.3 GO:0010043 response to zinc ion(GO:0010043)
0.1 15.6 GO:0008202 steroid metabolic process(GO:0008202)
0.1 9.7 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.1 40.3 GO:0006412 translation(GO:0006412)
0.1 4.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 15.1 GO:0007265 Ras protein signal transduction(GO:0007265)
0.1 1.9 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 16.9 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.1 0.7 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 2.2 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 0.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 11.3 GO:0006869 lipid transport(GO:0006869)
0.1 1.3 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 8.1 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0060134 prepulse inhibition(GO:0060134)
0.0 3.7 GO:0045216 cell-cell junction organization(GO:0045216)
0.0 0.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 15.4 GO:0006952 defense response(GO:0006952)
0.0 1.3 GO:0007264 small GTPase mediated signal transduction(GO:0007264)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
18.4 55.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
7.6 30.4 GO:0044393 microspike(GO:0044393)
6.3 50.7 GO:0005577 fibrinogen complex(GO:0005577)
5.2 25.8 GO:0043527 tRNA methyltransferase complex(GO:0043527)
4.3 34.1 GO:0005869 dynactin complex(GO:0005869)
4.2 21.1 GO:0035976 AP1 complex(GO:0035976)
3.7 11.0 GO:0005745 m-AAA complex(GO:0005745)
3.4 10.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
3.2 9.7 GO:0046691 intracellular canaliculus(GO:0046691)
3.0 54.8 GO:0071437 invadopodium(GO:0071437)
2.9 11.7 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
2.8 19.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
2.7 13.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.7 15.9 GO:0044308 axonal spine(GO:0044308)
2.5 40.5 GO:0031045 dense core granule(GO:0031045)
2.5 22.3 GO:0042583 chromaffin granule(GO:0042583)
2.3 25.1 GO:0072546 ER membrane protein complex(GO:0072546)
2.2 13.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
2.2 21.9 GO:0070652 HAUS complex(GO:0070652)
2.2 10.8 GO:0005828 kinetochore microtubule(GO:0005828)
2.1 27.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
2.0 15.8 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
1.9 5.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.8 16.6 GO:0000813 ESCRT I complex(GO:0000813)
1.8 8.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
1.7 5.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
1.7 13.3 GO:0032584 growth cone membrane(GO:0032584)
1.6 20.2 GO:0031143 pseudopodium(GO:0031143)
1.5 16.8 GO:0005915 zonula adherens(GO:0005915)
1.1 10.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.1 15.4 GO:0030127 COPII vesicle coat(GO:0030127)
1.1 16.1 GO:0044754 autolysosome(GO:0044754)
1.1 9.6 GO:0016461 unconventional myosin complex(GO:0016461)
1.0 20.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.0 8.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.9 22.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.9 8.8 GO:0070187 telosome(GO:0070187)
0.9 12.2 GO:0060091 kinocilium(GO:0060091)
0.9 24.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.8 17.5 GO:0005775 vacuolar lumen(GO:0005775)
0.8 7.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.8 9.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.8 2.3 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
0.8 20.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.7 5.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.7 8.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.7 5.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.7 3.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.7 9.9 GO:0035102 PRC1 complex(GO:0035102)
0.6 67.7 GO:0030175 filopodium(GO:0030175)
0.6 18.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.6 52.0 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.6 12.8 GO:0097440 apical dendrite(GO:0097440)
0.6 15.5 GO:0042629 mast cell granule(GO:0042629)
0.6 9.7 GO:0032039 integrator complex(GO:0032039)
0.6 42.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.6 40.1 GO:0005811 lipid particle(GO:0005811)
0.5 16.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.5 15.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.5 4.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.5 25.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.5 5.6 GO:0030008 TRAPP complex(GO:0030008)
0.5 42.4 GO:0031985 Golgi cisterna(GO:0031985)
0.5 1.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 4.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.4 23.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 12.7 GO:0043198 dendritic shaft(GO:0043198)
0.4 7.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4 2.2 GO:0070847 core mediator complex(GO:0070847)
0.4 6.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 7.9 GO:0030666 endocytic vesicle membrane(GO:0030666) phagocytic vesicle membrane(GO:0030670)
0.3 43.1 GO:0031256 leading edge membrane(GO:0031256)
0.3 77.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 3.6 GO:0043196 varicosity(GO:0043196)
0.3 7.8 GO:0008305 integrin complex(GO:0008305)
0.3 13.9 GO:0005844 polysome(GO:0005844)
0.3 40.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 31.8 GO:0043204 perikaryon(GO:0043204)
0.2 1.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) oxoglutarate dehydrogenase complex(GO:0045252)
0.2 3.1 GO:0042581 specific granule(GO:0042581)
0.2 51.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.2 4.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 12.4 GO:0005776 autophagosome(GO:0005776)
0.2 10.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 34.9 GO:0034702 ion channel complex(GO:0034702)
0.2 5.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 7.1 GO:0030315 T-tubule(GO:0030315)
0.2 1.3 GO:0005687 U4 snRNP(GO:0005687)
0.2 2.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 2.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 10.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 16.1 GO:0001650 fibrillar center(GO:0001650)
0.1 3.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 89.6 GO:0016604 nuclear body(GO:0016604)
0.1 3.0 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 22.9 GO:0000139 Golgi membrane(GO:0000139)
0.1 20.1 GO:0005840 ribosome(GO:0005840)
0.1 33.9 GO:0005768 endosome(GO:0005768)
0.1 9.9 GO:0043679 axon terminus(GO:0043679)
0.1 147.1 GO:0005739 mitochondrion(GO:0005739)
0.1 2.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 54.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 8.4 GO:0030426 growth cone(GO:0030426)
0.1 10.5 GO:0000922 spindle pole(GO:0000922)
0.1 131.7 GO:0005615 extracellular space(GO:0005615)
0.1 7.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 198.2 GO:0005576 extracellular region(GO:0005576)
0.1 6.2 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 7.5 GO:0005938 cell cortex(GO:0005938)
0.1 43.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.1 22.0 GO:0005794 Golgi apparatus(GO:0005794)
0.1 7.3 GO:0005925 focal adhesion(GO:0005925)
0.1 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 76.3 GO:0005829 cytosol(GO:0005829)
0.1 4.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 4.9 GO:0005911 cell-cell junction(GO:0005911)
0.0 150.8 GO:0016020 membrane(GO:0016020)
0.0 1.1 GO:0000793 condensed chromosome(GO:0000793)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
14.3 42.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
7.2 50.7 GO:0045340 mercury ion binding(GO:0045340)
6.4 32.0 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
5.1 15.2 GO:0031177 phosphopantetheine binding(GO:0031177)
4.8 24.0 GO:1990932 5.8S rRNA binding(GO:1990932)
4.6 18.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
4.2 12.7 GO:0052743 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) inositol tetrakisphosphate phosphatase activity(GO:0052743)
4.1 16.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
3.9 15.4 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
3.6 14.5 GO:0097108 hedgehog family protein binding(GO:0097108)
3.6 21.4 GO:0004994 somatostatin receptor activity(GO:0004994)
3.3 16.6 GO:0032564 dATP binding(GO:0032564)
3.2 12.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
3.1 21.4 GO:0051880 G-quadruplex DNA binding(GO:0051880)
3.0 60.0 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
2.9 11.7 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
2.9 14.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
2.8 19.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
2.7 27.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
2.7 8.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
2.7 13.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
2.6 21.2 GO:0030957 Tat protein binding(GO:0030957)
2.6 55.4 GO:0031996 thioesterase binding(GO:0031996)
2.6 36.6 GO:0035497 cAMP response element binding(GO:0035497)
2.6 20.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
2.6 62.3 GO:0005112 Notch binding(GO:0005112)
2.6 35.8 GO:0042043 neurexin family protein binding(GO:0042043)
2.5 12.7 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
2.5 64.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
2.4 9.7 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
2.4 7.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
2.3 25.8 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
2.3 9.4 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
2.2 8.8 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
2.2 11.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
2.1 6.4 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
2.1 6.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
2.1 8.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
2.0 12.3 GO:1990715 mRNA CDS binding(GO:1990715)
2.0 10.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
2.0 26.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
2.0 15.7 GO:0031419 cobalamin binding(GO:0031419)
1.8 37.0 GO:0005003 ephrin receptor activity(GO:0005003)
1.7 78.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.7 5.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
1.7 10.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
1.6 14.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
1.6 16.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.6 15.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
1.5 6.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.5 10.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
1.5 10.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
1.5 4.4 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
1.4 18.6 GO:1990405 protein antigen binding(GO:1990405)
1.4 11.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.4 30.2 GO:0051010 microtubule plus-end binding(GO:0051010)
1.3 7.8 GO:0070051 fibrinogen binding(GO:0070051)
1.3 5.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.2 32.4 GO:0042056 chemoattractant activity(GO:0042056)
1.2 29.5 GO:0031489 myosin V binding(GO:0031489)
1.2 39.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
1.2 9.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
1.2 19.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
1.1 27.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
1.0 7.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
1.0 3.1 GO:2001070 starch binding(GO:2001070)
1.0 14.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.9 5.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.9 20.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.9 17.5 GO:0005537 mannose binding(GO:0005537)
0.9 22.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.8 3.4 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.8 9.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.8 13.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.8 10.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.8 2.3 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.8 5.3 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.8 9.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.7 54.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.7 15.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.7 5.7 GO:0034452 dynactin binding(GO:0034452)
0.7 6.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.7 4.7 GO:0004177 aminopeptidase activity(GO:0004177)
0.6 13.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.6 13.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.6 16.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.6 10.2 GO:0097602 cullin family protein binding(GO:0097602)
0.6 15.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.5 13.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.5 9.2 GO:0048156 tau protein binding(GO:0048156)
0.5 8.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.5 18.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.5 74.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.5 5.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.5 24.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.5 14.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.5 1.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.5 10.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 4.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.5 3.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.5 12.2 GO:0008483 transaminase activity(GO:0008483)
0.4 13.5 GO:0003785 actin monomer binding(GO:0003785)
0.4 14.8 GO:0050699 WW domain binding(GO:0050699)
0.4 26.8 GO:0019843 rRNA binding(GO:0019843)
0.4 7.3 GO:0005521 lamin binding(GO:0005521)
0.4 4.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.4 5.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.4 30.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.4 8.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.4 15.4 GO:0005158 insulin receptor binding(GO:0005158)
0.4 10.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.4 32.9 GO:0051082 unfolded protein binding(GO:0051082)
0.4 10.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 13.4 GO:0042169 SH2 domain binding(GO:0042169)
0.3 39.2 GO:0030674 protein binding, bridging(GO:0030674)
0.3 31.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.3 16.1 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.3 10.1 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.3 21.0 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.3 7.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.3 1.8 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 10.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 17.5 GO:0008146 sulfotransferase activity(GO:0008146)
0.3 5.8 GO:0071837 HMG box domain binding(GO:0071837)
0.3 2.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 3.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.3 11.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.3 10.6 GO:0031491 nucleosome binding(GO:0031491)
0.3 6.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 4.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 12.1 GO:0035064 methylated histone binding(GO:0035064)
0.2 13.3 GO:0043621 protein self-association(GO:0043621)
0.2 28.1 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.2 53.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 7.6 GO:0030507 spectrin binding(GO:0030507)
0.2 43.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.2 51.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 1.9 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.2 59.1 GO:0045296 cadherin binding(GO:0045296)
0.2 70.1 GO:0005525 GTP binding(GO:0005525)
0.2 16.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.2 4.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 3.8 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.2 20.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 7.0 GO:0002039 p53 binding(GO:0002039)
0.2 18.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 3.6 GO:0030552 cAMP binding(GO:0030552)
0.2 3.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 14.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 10.4 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 69.5 GO:0005509 calcium ion binding(GO:0005509)
0.1 13.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 17.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 2.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 17.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 4.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 8.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 10.4 GO:0005179 hormone activity(GO:0005179)
0.1 9.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 4.8 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 2.2 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 15.6 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 2.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 4.0 GO:0008237 metallopeptidase activity(GO:0008237)
0.1 21.9 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 3.4 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.3 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.9 GO:0030276 clathrin binding(GO:0030276)
0.0 10.8 GO:0008289 lipid binding(GO:0008289)
0.0 0.7 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 1.1 GO:0008565 protein transporter activity(GO:0008565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 103.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
2.4 50.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
2.2 46.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
2.0 74.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
1.5 22.3 ST G ALPHA S PATHWAY G alpha s Pathway
1.4 46.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
1.3 30.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.2 37.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
1.0 9.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
1.0 22.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
1.0 39.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.9 18.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.8 32.4 PID ARF6 PATHWAY Arf6 signaling events
0.8 12.9 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.8 10.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.8 14.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.7 91.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.7 15.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.7 37.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.6 8.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.5 28.9 PID AP1 PATHWAY AP-1 transcription factor network
0.5 22.3 PID LKB1 PATHWAY LKB1 signaling events
0.4 4.9 ST JAK STAT PATHWAY Jak-STAT Pathway
0.4 7.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.4 20.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.4 10.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.4 8.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.3 6.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.3 5.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3 4.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 9.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.2 3.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 7.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 10.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 1.9 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.2 10.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 4.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 6.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 8.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 2.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 13.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 10.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 67.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
3.1 55.9 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
2.8 16.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
2.4 26.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
2.1 18.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
2.0 27.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
2.0 55.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
2.0 29.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
1.4 14.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
1.4 24.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.3 17.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
1.0 15.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.0 12.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.8 22.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.8 42.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.8 9.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.8 14.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.7 8.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.7 16.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.7 10.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.6 10.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.6 13.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.6 10.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.6 9.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.6 20.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.6 12.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.5 13.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.5 6.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.5 45.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.5 13.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.5 16.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.5 10.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.4 78.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.4 10.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 9.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.4 21.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.4 17.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 12.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.3 4.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.3 8.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 4.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 14.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.3 30.5 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.2 15.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 5.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 5.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 5.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 4.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 7.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 14.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 5.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 15.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 3.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 3.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 23.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 8.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 1.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 3.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 3.5 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation