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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Creb3

Z-value: 0.95

Motif logo

Transcription factors associated with Creb3

Gene Symbol Gene ID Gene Info
ENSRNOG00000016452 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Creb3rn6_v1_chr5_+_59063531_59063558-0.123.5e-02Click!

Activity profile of Creb3 motif

Sorted Z-values of Creb3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_40247436 36.78 ENSRNOT00000079830
glutathione peroxidase 3
chr3_-_175709465 33.30 ENSRNOT00000089971
GATA binding protein 5
chr7_+_141249044 33.19 ENSRNOT00000084911
aquaporin 5
chr7_+_120749752 29.94 ENSRNOT00000087888
KDEL endoplasmic reticulum protein retention receptor 3
chr8_+_58431407 28.75 ENSRNOT00000011974
sarcolipin
chr2_-_257474733 24.46 ENSRNOT00000016967
ENSRNOT00000066780
nexilin (F actin binding protein)
chr1_-_141893674 23.99 ENSRNOT00000019059
ENSRNOT00000085988
isocitrate dehydrogenase (NADP(+)) 2, mitochondrial
chr8_-_25904564 22.84 ENSRNOT00000082744
ENSRNOT00000064783
T-box 20
chr19_-_38120578 20.68 ENSRNOT00000026873
epithelial splicing regulatory protein 2
chr1_-_101085884 19.89 ENSRNOT00000085352
reticulocalbin 3
chr2_+_227455722 19.38 ENSRNOT00000064809
SEC24 homolog D, COPII coat complex component
chr8_-_21995806 18.77 ENSRNOT00000028034
sphingosine-1-phosphate receptor 2
chr8_-_13109487 17.15 ENSRNOT00000061616
angiomotin-like 1
chr3_-_146470293 15.49 ENSRNOT00000009627
acyl-CoA synthetase short-chain family member 1
chr10_+_36099263 14.86 ENSRNOT00000083568
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr5_-_173081839 14.15 ENSRNOT00000066880
matrix metallopeptidase 23
chr10_-_62483342 13.66 ENSRNOT00000079956
hypermethylated in cancer 1 protein-like
chr18_-_28428117 13.55 ENSRNOT00000078202
solute carrier family 23 member 1
chr6_-_7741414 13.33 ENSRNOT00000038246
THADA, armadillo repeat containing
chr10_+_16970626 13.30 ENSRNOT00000005383
dual specificity phosphatase 1
chr3_+_95232166 12.91 ENSRNOT00000017952
hypothetical protein LOC691083
chr1_-_87174530 12.73 ENSRNOT00000089578
potassium two pore domain channel subfamily K member 6
chr1_-_101086198 12.72 ENSRNOT00000027917
reticulocalbin 3
chr1_-_88176610 12.48 ENSRNOT00000032394
potassium channel subfamily K member 6-like
chr10_-_70337532 11.80 ENSRNOT00000055963
schlafen family member 13
chr8_+_117117430 11.71 ENSRNOT00000073247
glutathione peroxidase 1
chr3_+_45538797 11.65 ENSRNOT00000007632
death associated protein-like 1
chr4_+_98648545 11.46 ENSRNOT00000008451
eukaryotic translation initiation factor 2 alpha kinase 3
chrX_+_156999826 11.42 ENSRNOT00000081819
isocitrate dehydrogenase 3 (NAD), gamma
chr15_+_57891680 11.01 ENSRNOT00000001383
tumor protein, translationally-controlled 1
chr7_+_114724610 11.01 ENSRNOT00000014541
DENN domain containing 3
chr15_-_61564695 10.99 ENSRNOT00000068216
regulator of cell cycle
chr20_+_44680449 10.71 ENSRNOT00000000728
Traf3 interacting protein 2
chrX_-_156399760 10.67 ENSRNOT00000086921
family with sequence similarity 50, member A
chr5_+_164845925 9.81 ENSRNOT00000011384
methylenetetrahydrofolate reductase
chr4_+_56625561 9.69 ENSRNOT00000008356
ENSRNOT00000090808
ENSRNOT00000008972
calumenin
chr8_-_116361343 9.52 ENSRNOT00000066296
semaphorin 3B
chr18_+_52423883 9.49 ENSRNOT00000022017
proline-rich coiled-coil 1
chr10_-_65805693 9.43 ENSRNOT00000012245
TNF alpha induced protein 1
chr2_-_33841499 9.39 ENSRNOT00000040533
splicing regulatory glutamic acid and lysine rich protein 1
chr2_-_123282214 9.13 ENSRNOT00000021156
cyclin A2
chr11_+_46009322 9.07 ENSRNOT00000002233
transmembrane protein 45A
chr13_-_61070599 8.93 ENSRNOT00000005251
regulator of G-protein signaling 1
chr11_+_46714355 8.86 ENSRNOT00000073404
transmembrane protein 45A-like
chr1_-_82120902 8.84 ENSRNOT00000027684
Ets2 repressor factor
chr10_-_40764185 8.80 ENSRNOT00000017486
secreted protein acidic and cysteine rich
chr1_+_101859346 8.75 ENSRNOT00000028627
KDEL endoplasmic reticulum protein retention receptor 1
chr2_-_157759819 8.63 ENSRNOT00000015763
ENSRNOT00000016016
cyclin-L1-like
chr1_-_216663720 8.51 ENSRNOT00000078944
ENSRNOT00000077409
cyclin-dependent kinase inhibitor 1C
chr1_+_144831523 8.43 ENSRNOT00000039748
mex-3 RNA binding family member B
chr8_-_49308806 8.42 ENSRNOT00000047291
CD3e molecule
chr1_+_199941161 8.35 ENSRNOT00000027616
Bcl2-associated athanogene 3
chr19_-_37210412 8.28 ENSRNOT00000083097
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr15_+_45422010 7.94 ENSRNOT00000012231
ribonuclease H2, subunit B
chr7_-_2819299 7.85 ENSRNOT00000045547
solute carrier family 39 member 5
chr17_+_43616247 7.83 ENSRNOT00000072019
histone cluster 1, H3a
chr12_+_7081895 7.73 ENSRNOT00000047163
high mobility group box 1
chr20_+_46250363 7.71 ENSRNOT00000076522
ENSRNOT00000000334
CD164 molecule
chr6_+_132702448 7.63 ENSRNOT00000005743
YY1 transcription factor
chr15_-_34322115 7.50 ENSRNOT00000026734
transmembrane 9 superfamily member 1
chr3_+_150801289 7.47 ENSRNOT00000035060
microtubule-associated protein 1 light chain 3 alpha
chr2_-_123281856 7.23 ENSRNOT00000079745
cyclin A2
chr2_+_233615739 7.14 ENSRNOT00000051009
paired-like homeodomain 2
chrX_-_156999650 7.08 ENSRNOT00000083557
signal sequence receptor subunit 4
chr17_-_1797732 6.96 ENSRNOT00000033017
ENSRNOT00000079742
cell division cycle 14B
chr14_-_19072677 6.92 ENSRNOT00000060548
similar to alpha-fetoprotein
chr17_-_15718015 6.73 ENSRNOT00000048653
ENSRNOT00000090647
BICD cargo adaptor 2
chr5_+_63192298 6.21 ENSRNOT00000008329
Sec61 translocon beta subunit
chr5_-_138470096 6.11 ENSRNOT00000011392
phosphopantothenoylcysteine synthetase
chr3_+_113415774 6.08 ENSRNOT00000056151
small EDRK-rich factor 2
chr6_-_91456696 5.99 ENSRNOT00000005577
ribosomal protein S29
chr10_+_37032043 5.98 ENSRNOT00000037303
ENSRNOT00000091242
5-phosphohydroxy-L-lysine phospho-lyase
chr1_+_167309051 5.80 ENSRNOT00000055235
ENSRNOT00000076894
post-GPI attachment to proteins 2
chr3_-_122920684 5.72 ENSRNOT00000028818
carboxypeptidase X (M14 family), member 1
chrX_+_78259409 5.70 ENSRNOT00000049779
similar to RIKEN cDNA A630033H20 gene
chr2_-_20152884 5.70 ENSRNOT00000021941
autophagy related 10
chr11_-_64752544 5.63 ENSRNOT00000048738
transmembrane protein 39a
chr10_+_34938667 5.54 ENSRNOT00000086443
ENSRNOT00000059104
5-phosphohydroxy-L-lysine phospho-lyase
chr4_-_57625147 5.53 ENSRNOT00000074649
ENSRNOT00000078961
ubiquitin-conjugating enzyme E2H
chr10_+_56610051 5.50 ENSRNOT00000024348
dishevelled segment polarity protein 2
chr19_-_37938857 5.34 ENSRNOT00000026730
solute carrier family 12 member 4
chr1_-_87174821 5.29 ENSRNOT00000027974
potassium two pore domain channel subfamily K member 6
chr10_+_56524468 5.20 ENSRNOT00000022041
G protein pathway suppressor 2
chr14_+_11199404 5.20 ENSRNOT00000003106
heterogeneous nuclear ribonucleoprotein D-like
chrX_-_42329232 4.87 ENSRNOT00000045705
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
chr8_-_96203677 4.83 ENSRNOT00000074515
synaptotagmin binding, cytoplasmic RNA interacting protein
chr11_-_67647818 4.81 ENSRNOT00000003068
WD repeat domain 5B
chr1_-_282170017 4.73 ENSRNOT00000066947
eukaryotic translation initiation factor 3, subunit A
chr1_+_80141630 4.69 ENSRNOT00000029552
optic atrophy 3
chr6_+_10912383 4.52 ENSRNOT00000061747
ENSRNOT00000086247
tetratricopeptide repeat domain 7A
chr1_+_140601791 4.51 ENSRNOT00000091588
interferon stimulated exonuclease gene 20
chr5_-_117612123 4.47 ENSRNOT00000065112
dedicator of cytokinesis 7
chr4_-_66002444 4.43 ENSRNOT00000018645
zinc finger CCCH-type containing, antiviral 1 like
chr14_-_79988110 4.23 ENSRNOT00000090597
actin filament associated protein 1
chr1_+_114046478 4.19 ENSRNOT00000032254
sialic acid binding Ig-like lectin H
chr17_+_10463303 4.18 ENSRNOT00000060822
ring finger protein 44
chr20_+_31298269 4.18 ENSRNOT00000000673
pyrophosphatase (inorganic) 1
chr8_-_39243705 4.14 ENSRNOT00000043518
STT3A, catalytic subunit of the oligosaccharyltransferase complex
chr9_-_17827032 4.05 ENSRNOT00000026929
solute carrier family 35 member B2
chr7_-_59547174 3.95 ENSRNOT00000085836
CCR4-NOT transcription complex, subunit 2
chr17_+_89742140 3.94 ENSRNOT00000077899
microtubule associated serine/threonine kinase-like
chr17_+_26925828 3.91 ENSRNOT00000018310
thioredoxin domain containing 5
chr1_-_167308827 3.77 ENSRNOT00000027590
ENSRNOT00000027575
nucleoporin 98
chr10_-_75120247 3.77 ENSRNOT00000011402
lactoperoxidase
chr12_+_9728486 3.76 ENSRNOT00000001263
ligand of numb-protein X 2
chr3_+_177351518 3.65 ENSRNOT00000023989
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr14_+_11198896 3.63 ENSRNOT00000079767
heterogeneous nuclear ribonucleoprotein D-like
chr5_+_160306727 3.63 ENSRNOT00000016648
agmatinase
chr3_+_146695344 3.62 ENSRNOT00000010955
GINS complex subunit 1
chr14_+_35683442 3.44 ENSRNOT00000003085
cysteine-rich hydrophobic domain 2
chr10_+_4578469 3.43 ENSRNOT00000003332
thioredoxin domain containing 11
chr14_+_7949239 3.42 ENSRNOT00000044617
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4-like 1
chr13_+_89253617 3.40 ENSRNOT00000044575
ferritin light chain 1-like
chr16_-_71125316 3.35 ENSRNOT00000020900
phospholipid phosphatase 5
chr15_-_34338956 3.32 ENSRNOT00000026914
magnesium-dependent phosphatase 1
chr12_-_23021517 3.18 ENSRNOT00000041654
myosin light chain 10
chr3_+_67538289 3.08 ENSRNOT00000009839
DnaJ heat shock protein family (Hsp40) member C10
chr16_+_2338333 3.08 ENSRNOT00000017692
ADP-ribosylation factor 4
chr11_-_66819079 3.06 ENSRNOT00000003255
golgin B1
chr10_-_103736973 2.89 ENSRNOT00000004372
N-acetyltransferase 9
chr12_-_19314016 2.87 ENSRNOT00000001825
minichromosome maintenance complex component 7
chr7_+_2737765 2.86 ENSRNOT00000004895
canopy FGF signaling regulator 2
chr14_-_79987915 2.85 ENSRNOT00000089006
actin filament associated protein 1
chr12_-_6630274 2.82 ENSRNOT00000087840

chr16_-_49484985 2.82 ENSRNOT00000016723
UFM1-specific peptidase 2
chr9_+_55050203 2.82 ENSRNOT00000021403
nucleic acid binding protein 1
chr8_+_59164572 2.77 ENSRNOT00000015102
isocitrate dehydrogenase 3 (NAD+) alpha
chr8_-_39243882 2.77 ENSRNOT00000082086
STT3A, catalytic subunit of the oligosaccharyltransferase complex
chr3_+_8643936 2.75 ENSRNOT00000077797
SET nuclear proto-oncogene
chr4_-_165118062 2.74 ENSRNOT00000087219
Ly49s8
chr1_+_221420271 2.72 ENSRNOT00000028481
similar to Finkel-Biskis-Reilly murine sarcoma virusubiquitously expressed
chr4_+_119997268 2.71 ENSRNOT00000073429
ribophorin I
chr3_-_94686989 2.64 ENSRNOT00000016677
DEP domain containing 7
chr9_-_100592271 2.55 ENSRNOT00000086433
high density lipoprotein binding protein
chr20_+_3611964 2.50 ENSRNOT00000090510
ENSRNOT00000068159
diffuse panbronchiolitis critical region 1
chrX_+_120860178 2.48 ENSRNOT00000088661
WD repeat domain 44
chr5_+_5215196 2.45 ENSRNOT00000010481
translocation associated membrane protein 1
chr9_+_10013854 2.42 ENSRNOT00000077653
ENSRNOT00000072033
KH-type splicing regulatory protein
chr3_+_138504214 2.41 ENSRNOT00000091529
lysine acetyltransferase 14
chrX_-_123474154 2.38 ENSRNOT00000092415
ENSRNOT00000092455
similar to hypothetical protein FLJ22965
chr13_+_35554964 2.35 ENSRNOT00000072632
transmembrane protein 185B
chr11_+_65960277 2.33 ENSRNOT00000003674
NADH:ubiquinone oxidoreductase subunit B4
chr1_-_100865894 2.22 ENSRNOT00000027580
prostate tumor overexpressed 1
chr19_-_34105610 2.18 ENSRNOT00000017347
protein arginine methyltransferase 9
chr11_-_71591502 2.17 ENSRNOT00000002403
phosphate cytidylyltransferase 1, choline, alpha
chrX_+_120859968 1.96 ENSRNOT00000085185
WD repeat domain 44
chr17_-_84614228 1.86 ENSRNOT00000043042

chr1_-_84008293 1.86 ENSRNOT00000002053
small nuclear ribonucleoprotein polypeptide A
chr5_-_147846095 1.85 ENSRNOT00000072165
taxilin alpha
chr13_-_88497901 1.70 ENSRNOT00000058560
UDP-N-acetylglucosamine pyrophosphorylase 1
chr5_-_152247332 1.68 ENSRNOT00000077165
lin-28 homolog A
chr1_-_183729569 1.64 ENSRNOT00000083293
coatomer protein complex, subunit beta 1
chr1_+_256370850 1.63 ENSRNOT00000030962
cytochrome P450, family 26, subfamily C, polypeptide 1
chr7_-_11406771 1.63 ENSRNOT00000047450
eukaryotic translation elongation factor 2
chr19_-_37990353 1.55 ENSRNOT00000026817
DEAD-box helicase 28
chr10_+_82375572 1.52 ENSRNOT00000004947
mitochondrial ribosomal protein L27
chr8_+_81863619 1.50 ENSRNOT00000080608
family with sequence similarity 214, member A
chr6_+_91476698 1.47 ENSRNOT00000005608
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr10_+_103737162 1.47 ENSRNOT00000055037
transmembrane protein 104
chr10_+_38692211 1.45 ENSRNOT00000009440
AF4/FMR2 family, member 4
chr2_-_231881939 1.44 ENSRNOT00000074644
La ribonucleoprotein domain family, member 7
chr2_-_2891253 1.43 ENSRNOT00000029250
arylsulfatase family, member K
chr7_-_2972521 1.35 ENSRNOT00000061995
zinc finger CCCH type containing 10
chr18_+_1504178 1.35 ENSRNOT00000048198
ribosomal protein L36a-like
chr1_-_205842428 1.34 ENSRNOT00000024655
DEAH-box helicase 32 (putative)
chr8_-_50539331 1.26 ENSRNOT00000088997

chr8_-_112594261 1.24 ENSRNOT00000015240
ubiquitin-like modifier activating enzyme 5
chr2_+_195996521 1.14 ENSRNOT00000082849
pogo transposable element with ZNF domain
chr5_+_76150840 1.13 ENSRNOT00000020702
DnaJ heat shock protein family (Hsp40) member C25
chr15_-_39893979 1.10 ENSRNOT00000068353
cytidine and dCMP deaminase domain containing 1
chr10_-_105149971 1.08 ENSRNOT00000012436
signal recognition particle 68
chr3_-_124461332 1.07 ENSRNOT00000073088
putative ERV-F(c)1 provirus ancestral Env polyprotein
chr9_-_100624638 1.06 ENSRNOT00000051155
high density lipoprotein binding protein
chr7_-_123287721 1.03 ENSRNOT00000009152
NHP2 non-histone chromosome protein 2-like 1-like
chr6_-_26875376 1.01 ENSRNOT00000011838
transmembrane protein 214
chr16_+_61758917 0.99 ENSRNOT00000084858
leptin receptor overlapping transcript-like 1
chr2_-_261402880 0.99 ENSRNOT00000052396
ENSRNOT00000077839
ENSRNOT00000088561
fucose-1-phosphate guanylyltransferase
chr8_-_104995725 0.97 ENSRNOT00000037120
solute carrier family 25 member 36
chr1_-_219450451 0.94 ENSRNOT00000025317
RAD9 checkpoint clamp component A
chr10_-_96584896 0.94 ENSRNOT00000004699
ENSRNOT00000055073
protein kinase C, alpha
chr10_-_3321404 0.92 ENSRNOT00000093722
ENSRNOT00000003284
pyridoxal-dependent decarboxylase domain containing 1
chr18_-_56534415 0.92 ENSRNOT00000024374
solute carrier family 26 member 2
chr9_+_44491177 0.89 ENSRNOT00000075242
mitochondrial ribosomal protein L30
chr10_-_105228547 0.89 ENSRNOT00000028875
signal recognition particle 68
chr4_+_7260575 0.77 ENSRNOT00000064893
Fas-activated serine/threonine kinase
chr1_-_221420115 0.69 ENSRNOT00000028475
mitochondrial ribosomal protein L49
chr1_-_220067123 0.69 ENSRNOT00000071020
ENSRNOT00000072373
RNA binding motif protein 14
chr9_-_81566642 0.58 ENSRNOT00000080345
angio-associated, migratory cell protein
chr3_-_79892429 0.58 ENSRNOT00000016191
solute carrier family 39 member 13
chr2_-_30846149 0.57 ENSRNOT00000025506
solute carrier family 30 member 5
chr7_-_116872511 0.56 ENSRNOT00000010120
zinc finger CCCH type containing 3
chr2_-_152824547 0.54 ENSRNOT00000019824
DEAH-box helicase 36
chr4_+_55772377 0.48 ENSRNOT00000047698
staphylococcal nuclease and tudor domain containing 1
chr5_+_155935554 0.45 ENSRNOT00000031855
ubiquitin carboxyl-terminal hydrolase 48-like
chr3_+_160467552 0.45 ENSRNOT00000066657
serine/threonine kinase 4
chr7_+_72772440 0.44 ENSRNOT00000009989
metadherin
chr8_+_5790034 0.40 ENSRNOT00000061887
matrix metallopeptidase 27
chr5_-_59198650 0.40 ENSRNOT00000020958
olfactory receptor 833
chr20_+_28027054 0.39 ENSRNOT00000071386
ENSRNOT00000001044
RAN binding protein 2
chr4_-_84768249 0.35 ENSRNOT00000013205
FK506 binding protein 14

Network of associatons between targets according to the STRING database.

First level regulatory network of Creb3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.0 30.0 GO:0060577 pulmonary vein morphogenesis(GO:0060577)
6.4 38.2 GO:0006102 isocitrate metabolic process(GO:0006102)
5.7 17.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
5.5 38.7 GO:0006621 protein retention in ER lumen(GO:0006621)
5.3 36.8 GO:0002238 response to molecule of fungal origin(GO:0002238)
5.2 15.5 GO:0019541 acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
4.7 33.2 GO:0015670 carbon dioxide transport(GO:0015670)
4.5 13.6 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
4.1 28.7 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
3.9 11.7 GO:0009609 response to symbiotic bacterium(GO:0009609)
3.8 11.5 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
3.7 11.0 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
3.7 11.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
3.1 18.8 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
2.7 16.4 GO:0071314 cellular response to cocaine(GO:0071314)
2.6 7.8 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
2.6 7.7 GO:0035711 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) regulation of mismatch repair(GO:0032423) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) T-helper 1 cell activation(GO:0035711) positive regulation of glycogen catabolic process(GO:0045819) negative regulation of apoptotic cell clearance(GO:2000426)
2.6 18.0 GO:0060075 regulation of resting membrane potential(GO:0060075)
2.1 6.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
2.0 24.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.9 7.6 GO:0034696 response to prostaglandin F(GO:0034696)
1.7 8.4 GO:0072697 protein localization to cell cortex(GO:0072697)
1.6 9.8 GO:0070827 chromatin maintenance(GO:0070827)
1.6 10.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
1.5 4.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.5 8.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
1.4 8.5 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.4 8.4 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.3 3.8 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.2 33.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
1.2 4.7 GO:0002188 translation reinitiation(GO:0002188)
1.1 8.8 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.0 13.3 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
1.0 6.9 GO:0043686 co-translational protein modification(GO:0043686)
1.0 2.9 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.9 5.5 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.8 4.8 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.7 8.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.7 13.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.7 4.0 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.7 20.7 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.6 4.5 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.6 6.7 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.6 9.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.6 3.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.5 1.6 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.5 10.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.5 5.7 GO:0006983 ER overload response(GO:0006983)
0.5 4.0 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.5 7.5 GO:0010040 response to iron(II) ion(GO:0010040)
0.5 8.4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.5 8.8 GO:0009629 response to gravity(GO:0009629) response to L-ascorbic acid(GO:0033591)
0.5 3.6 GO:1902969 mitotic DNA replication(GO:1902969)
0.4 7.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.4 3.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.4 9.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.4 1.6 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.4 1.5 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.3 2.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.3 6.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.3 1.7 GO:0010587 miRNA catabolic process(GO:0010587) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3 0.9 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.3 14.9 GO:0030199 collagen fibril organization(GO:0030199)
0.3 3.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 5.8 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.2 2.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 5.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 0.5 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.2 4.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 4.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 5.2 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 1.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 1.0 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 8.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 3.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 1.9 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 7.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 4.5 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 1.0 GO:1901679 nucleotide transmembrane transport(GO:1901679)
0.1 6.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.4 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.7 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 3.6 GO:0006040 amino sugar metabolic process(GO:0006040)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 9.0 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.6 GO:0006824 cobalt ion transport(GO:0006824)
0.1 2.8 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1 0.6 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.9 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229)
0.1 7.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 11.8 GO:0051607 defense response to virus(GO:0051607)
0.1 0.2 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 5.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 6.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 3.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 2.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 1.8 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 2.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 3.6 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 2.5 GO:1903955 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 2.8 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.6 GO:0006882 cellular zinc ion homeostasis(GO:0006882)
0.0 4.1 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 3.1 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 0.4 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0 1.3 GO:0032526 response to retinoic acid(GO:0032526)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.4 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
4.7 14.2 GO:0005962 mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
2.8 11.0 GO:0045298 tubulin complex(GO:0045298)
2.7 13.3 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
2.4 9.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
2.2 8.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
2.1 10.6 GO:0097413 Lewy body(GO:0097413)
2.0 7.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
1.2 3.6 GO:0000811 GINS complex(GO:0000811)
1.2 16.9 GO:0030127 COPII vesicle coat(GO:0030127)
1.2 7.1 GO:0005642 annulate lamellae(GO:0005642)
1.1 8.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.9 3.8 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.8 28.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.8 46.7 GO:0009925 basal plasma membrane(GO:0009925)
0.8 4.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.7 2.8 GO:0070876 SOSS complex(GO:0070876)
0.6 4.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937) GAIT complex(GO:0097452)
0.6 4.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.6 9.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.6 15.0 GO:0000421 autophagosome membrane(GO:0000421)
0.4 17.5 GO:0008180 COP9 signalosome(GO:0008180)
0.4 7.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.4 18.9 GO:0016235 aggresome(GO:0016235)
0.4 2.0 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.3 6.8 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.3 3.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 2.9 GO:0042555 MCM complex(GO:0042555)
0.2 2.2 GO:0042587 glycogen granule(GO:0042587)
0.2 8.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 24.4 GO:0030018 Z disc(GO:0030018)
0.2 0.9 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 1.0 GO:0001651 dense fibrillar component(GO:0001651)
0.1 12.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 3.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 9.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.9 GO:0019028 viral capsid(GO:0019028)
0.1 2.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 4.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 7.8 GO:0000786 nucleosome(GO:0000786)
0.1 29.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 6.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 10.1 GO:0001650 fibrillar center(GO:0001650)
0.1 0.5 GO:0097433 dense body(GO:0097433)
0.1 8.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 7.1 GO:0005884 actin filament(GO:0005884)
0.1 10.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 20.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 2.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 11.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 23.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.7 GO:0005811 lipid particle(GO:0005811)
0.0 47.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.4 GO:0015030 Cajal body(GO:0015030)
0.0 11.3 GO:0000785 chromatin(GO:0000785)
0.0 9.9 GO:0016607 nuclear speck(GO:0016607)
0.0 4.1 GO:0005840 ribosome(GO:0005840)
0.0 1.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 10.8 GO:0005730 nucleolus(GO:0005730)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 17.3 GO:0005654 nucleoplasm(GO:0005654)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 38.7 GO:0046923 ER retention sequence binding(GO:0046923)
6.4 38.2 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
4.6 36.8 GO:0008430 selenium binding(GO:0008430)
4.5 13.6 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
4.4 13.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
3.9 15.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
2.4 33.2 GO:0015250 water channel activity(GO:0015250)
1.9 11.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.9 18.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
1.6 7.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.6 6.2 GO:0048408 epidermal growth factor binding(GO:0048408)
1.5 7.7 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
1.2 6.0 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
1.0 11.2 GO:0070513 death domain binding(GO:0070513)
1.0 4.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.9 1.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.9 3.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.9 4.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.9 13.7 GO:0008143 poly(A) binding(GO:0008143)
0.8 6.7 GO:0034452 dynactin binding(GO:0034452)
0.8 4.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.8 8.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.7 7.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.7 9.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.7 30.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.6 8.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.6 11.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.5 1.6 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.5 24.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.5 16.4 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.5 2.0 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.5 9.8 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.5 8.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 5.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.4 2.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 8.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 11.6 GO:0070412 R-SMAD binding(GO:0070412)
0.4 40.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.4 4.0 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.4 7.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 1.0 GO:0034512 box C/D snoRNA binding(GO:0034512)
0.3 0.9 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698) histone kinase activity (H3-T6 specific)(GO:0035403)
0.3 9.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 3.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.3 5.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.3 3.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 7.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 11.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 29.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 8.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.2 8.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.7 GO:0070569 uridylyltransferase activity(GO:0070569)
0.2 5.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 10.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 11.8 GO:0000049 tRNA binding(GO:0000049)
0.2 3.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 4.2 GO:0008483 transaminase activity(GO:0008483)
0.2 2.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 3.4 GO:0008199 ferric iron binding(GO:0008199)
0.2 3.8 GO:0004601 peroxidase activity(GO:0004601)
0.2 7.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 8.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 7.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.6 GO:0008097 5S rRNA binding(GO:0008097)
0.1 3.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 18.0 GO:0005267 potassium channel activity(GO:0005267)
0.1 23.3 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 1.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.0 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 14.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 3.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.5 GO:0019843 rRNA binding(GO:0019843)
0.1 3.5 GO:0003678 DNA helicase activity(GO:0003678)
0.1 8.4 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.8 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 5.8 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 13.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.5 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 30.6 GO:0030234 enzyme regulator activity(GO:0030234)
0.0 3.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 2.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 24.5 GO:0003723 RNA binding(GO:0003723)
0.0 5.2 GO:0004674 protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 16.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.8 18.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.6 33.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.5 15.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 7.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 18.0 PID PLK1 PATHWAY PLK1 signaling events
0.3 13.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 5.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 7.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 8.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 7.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 3.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 8.9 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 11.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 15.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 9.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.7 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 3.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 8.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 33.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
2.1 38.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
1.9 15.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.4 18.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
1.2 11.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.1 19.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.1 8.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.0 16.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.0 23.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.8 1.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.8 7.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.6 6.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.5 29.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 8.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.4 12.8 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.4 17.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3 41.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.3 14.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 10.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 19.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 16.0 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.2 8.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 4.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 2.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 4.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 25.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 4.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 6.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 2.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 2.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases