ISMARA results: Cpeb1

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Cpeb1

Z-value: 1.13

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Transcription factors associated with Cpeb1

Gene Symbol	Gene ID	Gene Info
Cpeb1 NCBI RGD Ensembl	ENSRNOG00000019161	cytoplasmic polyadenylation element binding protein 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Cpeb1	rn6_v1_chr1_-_143256817_143256817	0.60	7.0e-33	Click!

Activity profile of Cpeb1 motif

Sorted Z-values of Cpeb1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_93949187 Show fit	67.33	ENSRNOT00000018956	Zfp536 NCBI RGD Ensembl Show fit	zinc finger protein 536
chr3_+_98297554 Show fit	54.08	ENSRNOT00000006524	Kcna4 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily A member 4
chr20_-_54269525 Show fit	52.73	ENSRNOT00000037559	Grik2 NCBI RGD Ensembl Show fit	glutamate ionotropic receptor kainate type subunit 2
chr2_+_27905535 Show fit	48.06	ENSRNOT00000022120	Fam169a NCBI RGD Ensembl Show fit	family with sequence similarity 169, member A
chr3_+_129599353 Show fit	39.39	ENSRNOT00000008734	Snap25 NCBI RGD Ensembl Show fit	synaptosomal-associated protein 25
chr7_-_29701586 Show fit	39.04	ENSRNOT00000009084 ENSRNOT00000089269	Ano4 NCBI RGD Ensembl Show fit	anoctamin 4
chr10_-_27366665 Show fit	38.14	ENSRNOT00000004725	Gabra1 NCBI RGD Ensembl Show fit	gamma-aminobutyric acid type A receptor alpha1 subunit
chr6_+_113898420 Show fit	37.08	ENSRNOT00000064872	Nrxn3 NCBI RGD Ensembl Show fit	neurexin 3
chr6_-_136550371 Show fit	35.54	ENSRNOT00000065971	Rd3l NCBI RGD Ensembl Show fit	retinal degeneration 3-like
chr2_-_172361779 Show fit	35.44	ENSRNOT00000085876	Schip1 NCBI RGD Ensembl Show fit	schwannomin interacting protein 1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Cpeb1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.0	80.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.3	67.6	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
6.8	61.4	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2	43.6	GO:0016358	dendrite development(GO:0016358)
13.1	39.4	GO:1990926	short-term synaptic potentiation(GO:1990926)
7.8	39.0	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
2.7	38.1	GO:0071420	cellular response to histamine(GO:0071420)
2.1	37.1	GO:0090129	positive regulation of synapse maturation(GO:0090129)
2.0	35.9	GO:0021860	pyramidal neuron development(GO:0021860)
1.7	34.8	GO:0008210	estrogen metabolic process(GO:0008210)

Showing 1 to 10 of 160 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.0	108.8	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
6.4	57.7	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
2.5	56.6	GO:1902711	GABA-A receptor complex(GO:1902711)
0.3	56.3	GO:0045211	postsynaptic membrane(GO:0045211)
8.8	52.7	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.2	45.9	GO:0098793	presynapse(GO:0098793)
0.0	43.2	GO:0005829	cytosol(GO:0005829)
0.4	40.8	GO:0031225	anchored component of membrane(GO:0031225)
7.9	39.4	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3	35.2	GO:0043204	perikaryon(GO:0043204)

Showing 1 to 10 of 87 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.7	71.0	GO:0030955	potassium ion binding(GO:0030955)
7.5	60.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
7.5	52.7	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
1.1	51.4	GO:0005246	calcium channel regulator activity(GO:0005246)
1.4	47.2	GO:0017075	syntaxin-1 binding(GO:0017075)
1.7	40.0	GO:0002162	dystroglycan binding(GO:0002162)
2.0	39.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
7.6	38.1	GO:0008503	benzodiazepine receptor activity(GO:0008503) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.9	37.8	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
2.5	29.6	GO:0070008	serine-type exopeptidase activity(GO:0070008)

Showing 1 to 10 of 109 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	31.9	PID LKB1 PATHWAY	LKB1 signaling events
0.5	29.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.6	24.8	PID ATR PATHWAY	ATR signaling pathway
0.3	22.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.6	17.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3	17.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
1.1	16.9	PID S1P S1P4 PATHWAY	S1P4 pathway
0.6	16.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
1.0	13.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.3	13.0	PID ENDOTHELIN PATHWAY	Endothelins

Showing 1 to 10 of 30 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.1	59.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
3.3	56.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
3.3	52.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
2.8	39.4	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	31.7	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.9	28.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.5	26.1	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
1.4	23.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.8	22.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.6	17.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions

Showing 1 to 10 of 47 entries

Results for Cpeb1

Z-value: 1.13

Motif logo

Transcription factors associated with Cpeb1

Activity-expression correlation:

Activity profile of Cpeb1 motif

Sorted Z-values of Cpeb1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Cpeb1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: