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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Cpeb1

Z-value: 1.13

Motif logo

Transcription factors associated with Cpeb1

Gene Symbol Gene ID Gene Info
ENSRNOG00000019161 cytoplasmic polyadenylation element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cpeb1rn6_v1_chr1_-_143256817_1432568170.607.0e-33Click!

Activity profile of Cpeb1 motif

Sorted Z-values of Cpeb1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_93949187 67.33 ENSRNOT00000018956
zinc finger protein 536
chr3_+_98297554 54.08 ENSRNOT00000006524
potassium voltage-gated channel subfamily A member 4
chr20_-_54269525 52.73 ENSRNOT00000037559
glutamate ionotropic receptor kainate type subunit 2
chr2_+_27905535 48.06 ENSRNOT00000022120
family with sequence similarity 169, member A
chr3_+_129599353 39.39 ENSRNOT00000008734
synaptosomal-associated protein 25
chr7_-_29701586 39.04 ENSRNOT00000009084
ENSRNOT00000089269
anoctamin 4
chr10_-_27366665 38.14 ENSRNOT00000004725
gamma-aminobutyric acid type A receptor alpha1 subunit
chr6_+_113898420 37.08 ENSRNOT00000064872
neurexin 3
chr6_-_136550371 35.54 ENSRNOT00000065971
retinal degeneration 3-like
chr2_-_172361779 35.44 ENSRNOT00000085876
schwannomin interacting protein 1
chr4_-_108717309 32.38 ENSRNOT00000085062

chr9_+_73334618 31.86 ENSRNOT00000092717
microtubule-associated protein 2
chr9_-_32019205 31.59 ENSRNOT00000016194
adhesion G protein-coupled receptor B3
chr7_+_64768742 30.67 ENSRNOT00000005545
glutamate receptor interacting protein 1
chrX_+_122808605 29.07 ENSRNOT00000017567
zinc finger CCHC-type containing 12
chr2_+_136993208 28.99 ENSRNOT00000040187
ENSRNOT00000066542
protocadherin 10
chr13_-_88061108 28.48 ENSRNOT00000003774
regulator of G-protein signaling 4
chr2_+_184230459 28.43 ENSRNOT00000074187

chr17_-_18590536 28.33 ENSRNOT00000078992
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr10_-_18579632 26.16 ENSRNOT00000040737
potassium voltage-gated channel interacting protein 1
chr3_+_48096954 25.87 ENSRNOT00000068238
ENSRNOT00000064344
ENSRNOT00000044638
solute carrier family 4 member 10
chr18_-_37245809 24.75 ENSRNOT00000079585
protein phosphatase 2, regulatory subunit B, beta
chr5_-_85123829 24.05 ENSRNOT00000007578
BMP/retinoic acid inducible neural specific 1
chr8_+_23398030 23.38 ENSRNOT00000031893
similar to RIKEN cDNA 9530077C05
chr14_-_85191557 23.30 ENSRNOT00000011604
neurofilament heavy
chr5_-_65073012 23.08 ENSRNOT00000007957
glutamate ionotropic receptor NMDA type subunit 3A
chr15_+_17834635 23.07 ENSRNOT00000085530
similar to RIKEN cDNA 4933406L09
chr13_+_57243877 23.05 ENSRNOT00000083693
potassium sodium-activated channel subfamily T member 2
chr11_-_35098883 22.52 ENSRNOT00000079955
potassium voltage-gated channel subfamily J member 6
chr5_-_12563429 22.05 ENSRNOT00000059625
suppression of tumorigenicity 18
chr20_-_5064469 21.18 ENSRNOT00000001120
lymphocyte antigen 6 complex, locus G6D
chr9_+_73529612 21.00 ENSRNOT00000032430
unc-80 homolog, NALCN activator
chr18_-_18079560 20.20 ENSRNOT00000072093

chr2_+_187322416 19.72 ENSRNOT00000025183
cellular retinoic acid binding protein 2
chr2_+_263212051 19.58 ENSRNOT00000089396
neuronal growth regulator 1
chr7_-_136853154 19.54 ENSRNOT00000087376
neural EGFL like 2
chr2_-_98610368 19.07 ENSRNOT00000011641
zinc finger homeobox 4
chrX_-_152642531 18.51 ENSRNOT00000085037
gamma-aminobutyric acid type A receptor alpha3 subunit
chr6_-_8344574 17.49 ENSRNOT00000009660
prolyl endopeptidase-like
chr4_-_482645 17.40 ENSRNOT00000062073
ENSRNOT00000071713
canopy FGF signaling regulator 1
chr13_-_89565813 17.14 ENSRNOT00000004347
Purkinje cell protein 4-like 1
chr10_+_80790168 17.07 ENSRNOT00000073315
ENSRNOT00000075163
carbonic anhydrase 10
chr13_-_82753438 16.97 ENSRNOT00000075948
ATPase Na+/K+ transporting subunit beta 1
chr19_-_11669578 16.88 ENSRNOT00000026373
G protein subunit alpha o1
chr5_-_168734296 16.31 ENSRNOT00000066120
calmodulin binding transcription activator 1
chr3_-_51612397 16.16 ENSRNOT00000081401
sodium voltage-gated channel alpha subunit 3
chr1_-_174411141 16.15 ENSRNOT00000065288
nuclear receptor interacting protein 3
chr20_-_47910375 16.08 ENSRNOT00000000348
sine oculis binding protein homolog
chr6_+_58468155 15.99 ENSRNOT00000091263
ets variant 1
chrX_-_142164220 15.90 ENSRNOT00000064780
fibroblast growth factor 13
chr3_+_100786862 15.32 ENSRNOT00000080190
brain-derived neurotrophic factor
chr2_-_149444548 15.02 ENSRNOT00000018600
purinergic receptor P2Y12
chr2_+_207930796 14.61 ENSRNOT00000047827
potassium voltage-gated channel subfamily D member 3
chr7_-_70476340 14.61 ENSRNOT00000006800
Rho guanine nucleotide exchange factor 25
chr7_+_83113672 14.43 ENSRNOT00000006783
thyrotropin releasing hormone receptor
chr7_-_119352605 14.30 ENSRNOT00000008414
calcium voltage-gated channel auxiliary subunit gamma 2
chr6_-_23291568 13.95 ENSRNOT00000085708
CAP-GLY domain containing linker protein family, member 4
chr20_+_5049496 13.71 ENSRNOT00000088251
ENSRNOT00000001118
dimethylarginine dimethylaminohydrolase 2
chr18_+_13386133 13.66 ENSRNOT00000020661
additional sex combs like 3, transcriptional regulator
chr5_+_152680407 13.43 ENSRNOT00000076864
stathmin 1
chr15_-_80713153 13.35 ENSRNOT00000063800
kelch-like family member 1
chr9_+_100489852 13.18 ENSRNOT00000022854
protein phosphatase 1, regulatory subunit 7
chr2_-_2814690 12.67 ENSRNOT00000029265
G protein-coupled receptor 150
chr9_-_79898912 12.50 ENSRNOT00000022076
membrane associated ring-CH-type finger 4
chr15_-_43542939 12.30 ENSRNOT00000012996
dihydropyrimidinase-like 2
chr9_-_121713091 12.29 ENSRNOT00000073432
adenylate cyclase activating polypeptide 1
chr4_+_3959640 12.25 ENSRNOT00000009439
PAX interacting protein 1
chr6_-_8344897 12.15 ENSRNOT00000082353
prolyl endopeptidase-like
chr5_+_2278357 11.89 ENSRNOT00000066590
staufen double-stranded RNA binding protein 2
chr20_+_3422461 11.69 ENSRNOT00000084917
ENSRNOT00000079854
tubulin, beta 5 class I
chr7_-_116255167 11.59 ENSRNOT00000038109
ENSRNOT00000041774
cytochrome P450, family 11, subfamily b, polypeptide 2
chr7_+_44009069 11.59 ENSRNOT00000005523
MGAT4 family, member C
chr10_+_77537340 11.40 ENSRNOT00000003297
transmembrane protein 100
chr7_-_116161708 10.75 ENSRNOT00000068707
cytochrome P450, family 11, subfamily b, polypeptide 2
chr2_+_22910236 10.72 ENSRNOT00000078266
homer scaffolding protein 1
chr19_+_20147037 10.41 ENSRNOT00000020028
zinc finger protein 423
chrX_+_51286737 10.34 ENSRNOT00000035692
dystrophin
chr1_+_142679345 10.20 ENSRNOT00000034267
zinc finger and SCAN domain containing 2
chr6_+_8669722 10.17 ENSRNOT00000048550
calmodulin-lysine N-methyltransferase
chr2_-_186232292 10.04 ENSRNOT00000087088
doublecortin-like kinase 2
chr2_-_154418629 10.01 ENSRNOT00000076274
ENSRNOT00000076165
phospholipase C, eta 1
chr2_+_239415046 9.93 ENSRNOT00000072196
CXXC finger protein 4
chr8_-_44327551 9.64 ENSRNOT00000083939
GRAM domain containing 1B
chr1_+_64928503 9.57 ENSRNOT00000086274
vomeronasal 2 receptor, 80
chr9_+_88494676 9.55 ENSRNOT00000089451
mitochondrial fission factor-like
chr3_+_47677720 9.55 ENSRNOT00000065340
T-box, brain, 1
chr10_-_64657089 9.37 ENSRNOT00000080703
active BCR-related
chr20_+_25990304 9.33 ENSRNOT00000033980
leucine rich repeat transmembrane neuronal 3
chr2_-_154418920 9.23 ENSRNOT00000076326
phospholipase C, eta 1
chrX_-_30831483 9.22 ENSRNOT00000004443
glycine receptor, alpha 2
chr8_+_98745310 9.08 ENSRNOT00000019938
Zic family member 4
chr8_+_45797315 8.47 ENSRNOT00000059997

chr11_+_31389514 8.45 ENSRNOT00000000325
oligodendrocyte lineage transcription factor 2
chr6_+_94835845 8.35 ENSRNOT00000006321
JNK1/MAPK8-associated membrane protein
chr9_-_88534710 8.32 ENSRNOT00000020880
transmembrane 4 L six family member 20
chr18_-_16542165 8.16 ENSRNOT00000079381
solute carrier family 39 member 6
chr8_-_60570058 8.16 ENSRNOT00000009169
S-phase cyclin A-associated protein in the ER
chr4_-_79989572 8.11 ENSRNOT00000013264
ENSRNOT00000086453
deafness, autosomal dominant 5 (human)
chr4_-_29778039 8.10 ENSRNOT00000074177
sarcoglycan, epsilon
chr18_+_65285318 8.06 ENSRNOT00000020431
transcription factor 4
chr14_+_104250617 8.05 ENSRNOT00000079874
sprouty-related, EVH1 domain containing 2
chr3_-_61488696 7.94 ENSRNOT00000083045
lunapark, ER junction formation factor
chr1_-_250626844 7.90 ENSRNOT00000077135
N-acylsphingosine amidohydrolase 2
chr5_+_58667885 7.81 ENSRNOT00000064755
unc-13 homolog B
chr11_-_782954 7.76 ENSRNOT00000040065
Eph receptor A3
chr3_+_95715193 7.73 ENSRNOT00000089525
paired box 6
chr20_-_10013190 7.60 ENSRNOT00000084726
ENSRNOT00000089112
radial spoke head 1 homolog
chr5_+_139394794 7.49 ENSRNOT00000045954
sex comb on midleg homolog 1 (Drosophila)
chr5_+_4373626 7.45 ENSRNOT00000064946
EYA transcriptional coactivator and phosphatase 1
chr7_-_94563001 7.43 ENSRNOT00000051139
ENSRNOT00000005561
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr4_-_23718047 7.36 ENSRNOT00000011359
similar to RIKEN cDNA 4921511H03
chr9_-_19613360 7.27 ENSRNOT00000029593
regulator of calcineurin 2
chr18_+_29993361 7.23 ENSRNOT00000075810
protocadherin alpha 4
chrX_+_984798 7.20 ENSRNOT00000073016
zinc finger protein 182
chr18_+_59748444 7.19 ENSRNOT00000024752
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr8_-_67040005 7.11 ENSRNOT00000038641
glucuronic acid epimerase
chr7_+_64769089 7.11 ENSRNOT00000088861
glutamate receptor interacting protein 1
chr2_-_192027225 7.07 ENSRNOT00000016430
proline rich 9
chr15_-_88036354 6.98 ENSRNOT00000014747
endothelin receptor type B
chr7_-_33916338 6.95 ENSRNOT00000005492
cilia and flagella associated protein 54
chr17_+_44528125 6.95 ENSRNOT00000084538
similar to Histone H2A type 1
chr2_+_216863428 6.83 ENSRNOT00000068413
collagen type XI alpha 1 chain
chr10_-_73629581 6.78 ENSRNOT00000091172
BRCA1 interacting protein C-terminal helicase 1
chr1_-_246110218 6.77 ENSRNOT00000077544
regulatory factor X3
chr8_-_47404010 6.76 ENSRNOT00000038647
transmembrane protein 136
chr2_-_234296145 6.76 ENSRNOT00000014155
ELOVL fatty acid elongase 6
chr2_+_260249566 6.75 ENSRNOT00000089358
solute carrier family 44, member 5
chr16_-_9658484 6.68 ENSRNOT00000065216
mitogen-activated protein kinase 8
chr15_-_48284548 6.54 ENSRNOT00000038336
homeobox containing 1
chr3_-_157049666 6.50 ENSRNOT00000089958
chromodomain helicase DNA binding protein 6
chr16_-_32421005 6.39 ENSRNOT00000082712
NIMA-related kinase 1
chr10_-_87136026 6.37 ENSRNOT00000014230
ENSRNOT00000083233
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr1_+_30681681 6.28 ENSRNOT00000015395
R-spondin 3
chr5_-_155204456 6.28 ENSRNOT00000089574
Eph receptor B2
chr12_+_18931477 6.26 ENSRNOT00000077087
sprouty RTK signaling antagonist 3
chr7_+_144865608 6.18 ENSRNOT00000091596
ENSRNOT00000055285
heterogeneous nuclear ribonucleoprotein A1
chr6_+_6946695 6.09 ENSRNOT00000061921
metastasis associated 1 family, member 3
chr15_-_2966576 6.05 ENSRNOT00000070893
ENSRNOT00000017383
lysine acetyltransferase 6B
chr17_-_22143324 6.04 ENSRNOT00000019361
endothelin 1
chr16_-_20939545 5.98 ENSRNOT00000027457
SURP and G patch domain containing 2
chr17_-_21484456 5.97 ENSRNOT00000038180
synaptonemal complex protein 2-like
chr18_+_30820321 5.71 ENSRNOT00000060472
protocadherin gamma subfamily A, 3
chr5_+_58855773 5.64 ENSRNOT00000072869
RUN and SH3 domain containing 2
chr14_+_69800156 5.60 ENSRNOT00000072746
ligand dependent nuclear receptor corepressor-like
chr2_+_234375315 5.59 ENSRNOT00000071270
elongation of very long chain fatty acids protein 6-like
chr5_-_6186329 5.59 ENSRNOT00000012610
sulfatase 1
chr5_-_7874909 5.57 ENSRNOT00000064774
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr10_+_76320041 5.56 ENSRNOT00000037693
coilin
chr3_+_137154086 5.55 ENSRNOT00000034252
otoraplin
chrX_+_156655960 5.52 ENSRNOT00000085723
methyl CpG binding protein 2
chr10_+_90230441 5.44 ENSRNOT00000082722
transmembrane and ubiquitin-like domain containing 2
chr1_+_221596148 5.43 ENSRNOT00000028536
glycoprotein hormone alpha 2
chr5_+_164796185 5.39 ENSRNOT00000010779
natriuretic peptide B
chr8_-_18762922 5.18 ENSRNOT00000008423
olfactory receptor 1122
chr15_+_37171052 5.11 ENSRNOT00000011684
zinc finger MYM-type containing 2
chr18_-_26211445 5.03 ENSRNOT00000027739
neuronal regeneration related protein
chrX_-_9999401 5.03 ENSRNOT00000060992
G protein-coupled receptor 82
chr18_+_40853988 5.02 ENSRNOT00000091759
uncharacterized protein LOC317165
chr9_+_2190915 4.94 ENSRNOT00000077417
SATB homeobox 1
chr9_-_44419998 4.89 ENSRNOT00000091397
ENSRNOT00000083747
testis specific 10
chr14_-_19159923 4.86 ENSRNOT00000003879
alpha-fetoprotein
chr3_-_157099306 4.83 ENSRNOT00000022861
chromodomain helicase DNA binding protein 6
chr4_+_118207862 4.80 ENSRNOT00000085787
ENSRNOT00000023103
TIA1 cytotoxic granule-associated RNA binding protein
chr1_-_20962526 4.73 ENSRNOT00000061332
ENSRNOT00000017322
ENSRNOT00000017412
ENSRNOT00000079688
ENSRNOT00000017417
erythrocyte membrane protein band 4.1-like 2
chr10_+_90230711 4.71 ENSRNOT00000055185
transmembrane and ubiquitin-like domain containing 2
chr9_+_51298426 4.68 ENSRNOT00000065212
GULP, engulfment adaptor PTB domain containing 1
chr8_+_5522739 4.59 ENSRNOT00000011507
matrix metallopeptidase 13
chr4_-_2201749 4.43 ENSRNOT00000089327
limb development membrane protein 1
chr1_-_255815733 4.42 ENSRNOT00000047387
cytoplasmic polyadenylation element binding protein 3
chr10_+_35343189 4.34 ENSRNOT00000083688
mitogen-activated protein kinase 9
chr3_+_100787449 4.28 ENSRNOT00000078543
brain-derived neurotrophic factor
chr11_+_73022063 4.22 ENSRNOT00000002361
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr8_-_6235967 4.05 ENSRNOT00000068290
hypothetical protein LOC654482
chr2_+_149843282 4.03 ENSRNOT00000074805
similar to hypothetical protein C130079G13
chr4_+_2055615 3.97 ENSRNOT00000007646
ring finger protein 32
chr11_-_81379640 3.94 ENSRNOT00000002484
eukaryotic translation initiation factor 4A2
chr3_+_150135821 3.93 ENSRNOT00000047286
zinc finger protein 341
chr4_-_77510202 3.93 ENSRNOT00000038550
zinc finger protein 786
chr2_+_22909569 3.91 ENSRNOT00000073871
homer scaffolding protein 1
chr19_-_29016521 3.89 ENSRNOT00000049860
similar to spermatogenesis associated glutamate (E)-rich protein 4d
chr17_-_9458288 3.84 ENSRNOT00000075725
similar to RIKEN cDNA B230219D22
chr6_-_135251073 3.84 ENSRNOT00000088986
MOK protein kinase
chr8_+_5676665 3.83 ENSRNOT00000012310
matrix metallopeptidase 3
chr17_+_36334147 3.82 ENSRNOT00000050261
E2F transcription factor 3
chrX_-_158288109 3.68 ENSRNOT00000072527
PHD finger protein 6
chr3_-_66279155 3.67 ENSRNOT00000079887
ceramide kinase-like
chr2_-_149088787 3.66 ENSRNOT00000064833
clarin 1
chr13_-_86671515 3.66 ENSRNOT00000082869

chr6_+_108285822 3.59 ENSRNOT00000015889
visual system homeobox 2
chr1_+_282134981 3.45 ENSRNOT00000036203
nanos C2HC-type zinc finger 1
chr5_-_152473868 3.43 ENSRNOT00000022130
family with sequence similarity 110, member D
chr5_+_107233230 3.34 ENSRNOT00000029976
interferon, epsilon
chr1_+_263968134 3.33 ENSRNOT00000018090
similar to stearoyl-coenzyme A desaturase 3
chr13_-_47440682 3.27 ENSRNOT00000037679
ENSRNOT00000005729
ENSRNOT00000050354
ENSRNOT00000050859
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr5_-_174921 3.20 ENSRNOT00000056239
TIMELESS interacting protein like 1
chr16_-_10802512 3.17 ENSRNOT00000079554
bone morphogenetic protein receptor type 1A
chr1_-_198900375 3.14 ENSRNOT00000024969
zinc finger protein 689
chr7_+_132378273 3.14 ENSRNOT00000010990
hypothetical protein LOC690142
chrX_+_11084317 3.11 ENSRNOT00000031808
ENSRNOT00000093745
similar to RIKEN cDNA 1810030O07
chr8_+_107508351 2.95 ENSRNOT00000081594
centrosomal protein 70

Network of associatons between targets according to the STRING database.

First level regulatory network of Cpeb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
13.1 39.4 GO:1990926 short-term synaptic potentiation(GO:1990926)
7.8 39.0 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
7.8 23.3 GO:0033693 neurofilament bundle assembly(GO:0033693)
6.8 61.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
6.3 31.6 GO:0061743 motor learning(GO:0061743)
5.8 29.1 GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
5.7 17.0 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
3.7 22.3 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
3.6 14.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
3.4 10.3 GO:0021627 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
3.4 13.4 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
3.3 13.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
3.2 3.2 GO:0048378 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
3.1 9.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
3.1 12.3 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
3.0 11.9 GO:0098963 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
3.0 80.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
2.8 8.4 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
2.7 8.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
2.7 38.1 GO:0071420 cellular response to histamine(GO:0071420)
2.6 7.8 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
2.6 7.7 GO:1904937 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
2.5 7.4 GO:1903165 response to polycyclic arene(GO:1903165)
2.4 7.2 GO:1990743 protein sialylation(GO:1990743)
2.3 2.3 GO:1902304 positive regulation of potassium ion export(GO:1902304)
2.3 15.9 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
2.3 6.8 GO:2000078 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
2.2 31.3 GO:0007614 short-term memory(GO:0007614)
2.2 6.7 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
2.2 19.7 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
2.2 28.0 GO:0071317 cellular response to isoquinoline alkaloid(GO:0071317)
2.1 37.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
2.0 35.9 GO:0021860 pyramidal neuron development(GO:0021860)
1.9 5.7 GO:0060988 lipid tube assembly(GO:0060988)
1.9 11.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
1.8 7.1 GO:0030210 heparin biosynthetic process(GO:0030210)
1.8 12.3 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
1.7 6.8 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
1.7 34.8 GO:0008210 estrogen metabolic process(GO:0008210)
1.6 24.8 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
1.6 23.1 GO:0060134 prepulse inhibition(GO:0060134)
1.6 11.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
1.6 19.5 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
1.6 16.2 GO:0046684 response to pyrethroid(GO:0046684)
1.6 6.3 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
1.5 6.2 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
1.5 8.8 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
1.5 16.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
1.4 15.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
1.4 9.5 GO:0021902 conditioned taste aversion(GO:0001661) commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.4 6.8 GO:1990918 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
1.3 14.6 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
1.3 14.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
1.2 7.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.2 24.6 GO:0045760 positive regulation of action potential(GO:0045760)
1.2 3.5 GO:0098749 cerebellar neuron development(GO:0098749)
1.1 7.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
1.1 4.4 GO:0045900 negative regulation of translational elongation(GO:0045900)
1.1 5.4 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
1.1 13.7 GO:0006527 arginine catabolic process(GO:0006527)
1.0 14.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
1.0 2.9 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364)
0.9 4.6 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.9 12.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.9 4.3 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.8 9.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.8 9.3 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.8 18.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.8 6.8 GO:0035989 tendon development(GO:0035989)
0.8 21.2 GO:1903831 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.7 8.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.7 2.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.7 28.5 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.7 4.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.7 25.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.7 2.7 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.7 6.5 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.6 8.1 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.6 16.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.6 2.3 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.6 1.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.5 3.8 GO:0071460 negative regulation of hydrogen peroxide metabolic process(GO:0010727) cellular response to cell-matrix adhesion(GO:0071460)
0.5 3.2 GO:0048478 replication fork protection(GO:0048478)
0.5 1.6 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.5 28.3 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.5 6.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.5 2.4 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.5 1.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.5 5.6 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.5 3.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.5 1.8 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.5 3.7 GO:0050957 equilibrioception(GO:0050957)
0.4 6.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.4 8.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.4 1.7 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.4 2.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.4 1.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.4 2.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 6.9 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.4 2.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.4 4.9 GO:0042448 progesterone metabolic process(GO:0042448)
0.4 4.9 GO:0060004 reflex(GO:0060004)
0.4 2.6 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.4 6.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.4 6.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.3 16.1 GO:0090102 cochlea development(GO:0090102)
0.3 13.3 GO:0007628 adult walking behavior(GO:0007628)
0.3 1.0 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.3 3.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.3 67.6 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.3 16.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.3 1.2 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.3 10.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.3 5.5 GO:0001502 cartilage condensation(GO:0001502)
0.2 9.1 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.2 25.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 2.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 43.6 GO:0016358 dendrite development(GO:0016358)
0.2 2.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.2 4.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.2 3.7 GO:0045109 intermediate filament organization(GO:0045109)
0.2 6.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 13.1 GO:0007631 feeding behavior(GO:0007631)
0.1 5.4 GO:0018149 peptide cross-linking(GO:0018149)
0.1 8.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 2.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 3.8 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.1 14.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 11.7 GO:0051225 spindle assembly(GO:0051225)
0.1 0.2 GO:0001966 thigmotaxis(GO:0001966)
0.1 8.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 0.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 2.0 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 6.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 1.5 GO:1902358 sulfate transport(GO:0008272) oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.1 9.7 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.1 0.4 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 10.0 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.1 5.0 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.1 0.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 7.6 GO:0007286 spermatid development(GO:0007286)
0.1 2.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 1.5 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.2 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 1.2 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 2.7 GO:0006497 protein lipidation(GO:0006497)
0.0 2.1 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.9 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 1.2 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.7 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.6 GO:0030901 midbrain development(GO:0030901)
0.0 3.3 GO:0016042 lipid catabolic process(GO:0016042)
0.0 3.4 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.8 52.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
7.9 39.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
6.4 57.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
2.5 56.6 GO:1902711 GABA-A receptor complex(GO:1902711)
2.3 6.8 GO:0005592 collagen type XI trimer(GO:0005592)
2.1 23.3 GO:0097418 neurofibrillary tangle(GO:0097418)
2.1 31.6 GO:0043083 synaptic cleft(GO:0043083)
1.6 23.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.4 17.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.3 8.1 GO:0016012 sarcoglycan complex(GO:0016012)
1.3 7.8 GO:0044305 calyx of Held(GO:0044305)
1.3 14.3 GO:0099634 postsynaptic specialization membrane(GO:0099634)
1.2 4.8 GO:0097165 nuclear stress granule(GO:0097165)
1.2 11.7 GO:0005641 nuclear envelope lumen(GO:0005641)
1.2 19.6 GO:0030061 mitochondrial crista(GO:0030061)
1.0 108.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
1.0 6.0 GO:0033093 Weibel-Palade body(GO:0033093) rough endoplasmic reticulum lumen(GO:0048237)
0.9 11.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.9 22.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.8 5.8 GO:0001674 female germ cell nucleus(GO:0001674)
0.8 16.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.8 10.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.7 18.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.6 6.0 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.6 8.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.6 11.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.5 7.6 GO:0072687 meiotic spindle(GO:0072687)
0.5 6.4 GO:0071564 npBAF complex(GO:0071564)
0.5 1.6 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.5 2.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.5 13.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.5 2.3 GO:0045098 type III intermediate filament(GO:0045098)
0.4 6.1 GO:0008278 cohesin complex(GO:0008278)
0.4 6.0 GO:0000800 lateral element(GO:0000800)
0.4 16.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 14.6 GO:0043034 costamere(GO:0043034)
0.4 40.8 GO:0031225 anchored component of membrane(GO:0031225)
0.4 4.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.4 15.0 GO:0009925 basal plasma membrane(GO:0009925)
0.3 1.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 3.2 GO:0031298 replication fork protection complex(GO:0031298)
0.3 4.4 GO:0097440 apical dendrite(GO:0097440)
0.3 1.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.3 4.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 56.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 6.4 GO:0000242 pericentriolar material(GO:0000242)
0.3 5.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 35.2 GO:0043204 perikaryon(GO:0043204)
0.2 24.6 GO:0043195 terminal bouton(GO:0043195)
0.2 1.4 GO:0097542 ciliary tip(GO:0097542)
0.2 10.1 GO:0030658 transport vesicle membrane(GO:0030658)
0.2 5.4 GO:0001533 cornified envelope(GO:0001533)
0.2 3.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 45.9 GO:0098793 presynapse(GO:0098793)
0.2 8.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 12.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 1.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 10.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 3.8 GO:0097546 ciliary base(GO:0097546)
0.1 5.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.9 GO:0005801 cis-Golgi network(GO:0005801)
0.1 13.2 GO:0005795 Golgi stack(GO:0005795)
0.1 3.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 10.1 GO:0016605 PML body(GO:0016605)
0.1 2.3 GO:0042629 mast cell granule(GO:0042629)
0.1 1.8 GO:0005605 basal lamina(GO:0005605)
0.1 27.9 GO:0030425 dendrite(GO:0030425)
0.1 5.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 1.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 10.8 GO:0032993 protein-DNA complex(GO:0032993)
0.1 14.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 7.7 GO:0005925 focal adhesion(GO:0005925)
0.0 4.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.6 GO:0031526 brush border membrane(GO:0031526)
0.0 2.7 GO:0030017 sarcomere(GO:0030017)
0.0 11.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 8.1 GO:0005874 microtubule(GO:0005874)
0.0 6.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.2 GO:1902911 protein kinase complex(GO:1902911)
0.0 4.2 GO:0045202 synapse(GO:0045202)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 43.2 GO:0005829 cytosol(GO:0005829)
0.0 0.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.8 GO:0005813 centrosome(GO:0005813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 38.1 GO:0008503 benzodiazepine receptor activity(GO:0008503) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
7.5 52.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
7.5 60.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
7.4 22.3 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
6.4 19.2 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
4.6 13.7 GO:0016403 dimethylargininase activity(GO:0016403)
4.5 22.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
3.7 71.0 GO:0030955 potassium ion binding(GO:0030955)
3.1 9.2 GO:0022852 glycine-gated chloride ion channel activity(GO:0022852)
2.9 14.6 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
2.9 14.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
2.9 23.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
2.8 16.9 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
2.7 8.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
2.5 15.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
2.5 7.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
2.5 29.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
2.5 19.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
2.4 7.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
2.1 8.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
2.0 6.0 GO:0031708 endothelin B receptor binding(GO:0031708)
2.0 16.1 GO:0032184 SUMO polymer binding(GO:0032184)
2.0 39.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.9 29.1 GO:0032183 SUMO binding(GO:0032183)
1.9 37.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
1.8 7.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.8 5.4 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
1.7 40.0 GO:0002162 dystroglycan binding(GO:0002162)
1.7 28.3 GO:0008179 adenylate cyclase binding(GO:0008179)
1.5 19.7 GO:0019841 retinol binding(GO:0019841)
1.5 21.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
1.4 7.0 GO:0004962 endothelin receptor activity(GO:0004962)
1.4 47.2 GO:0017075 syntaxin-1 binding(GO:0017075)
1.4 23.3 GO:0015643 toxic substance binding(GO:0015643)
1.3 7.9 GO:0017040 ceramidase activity(GO:0017040)
1.2 12.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.2 4.7 GO:0042731 PH domain binding(GO:0042731)
1.2 16.2 GO:0031402 sodium ion binding(GO:0031402)
1.1 8.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
1.1 18.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
1.1 51.4 GO:0005246 calcium channel regulator activity(GO:0005246)
1.1 5.5 GO:0045322 unmethylated CpG binding(GO:0045322)
1.1 11.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.0 6.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.0 26.8 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.9 28.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.9 6.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.9 7.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.9 2.6 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.9 23.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.8 18.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.8 6.5 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.8 7.7 GO:0003680 AT DNA binding(GO:0003680)
0.7 3.7 GO:0001729 ceramide kinase activity(GO:0001729)
0.7 11.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.6 16.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.6 1.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.6 7.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.6 5.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.6 26.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.5 3.2 GO:0098821 BMP receptor activity(GO:0098821)
0.5 4.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.5 2.3 GO:1990254 keratin filament binding(GO:1990254)
0.4 27.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.4 15.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.4 15.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.3 29.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 1.2 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.3 3.3 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3 8.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 16.7 GO:0005080 protein kinase C binding(GO:0005080)
0.2 4.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 1.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 24.3 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.2 2.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 4.8 GO:0017091 AU-rich element binding(GO:0017091)
0.2 1.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 1.6 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.2 5.6 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.2 2.0 GO:0035497 cAMP response element binding(GO:0035497)
0.2 5.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 6.3 GO:0005109 frizzled binding(GO:0005109)
0.1 0.7 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 1.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 12.4 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 8.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 2.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 24.5 GO:0005096 GTPase activator activity(GO:0005096)
0.1 2.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 4.6 GO:0019894 kinesin binding(GO:0019894)
0.1 2.0 GO:0050681 androgen receptor binding(GO:0050681)
0.1 4.8 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 8.3 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.1 21.4 GO:0015631 tubulin binding(GO:0015631)
0.1 2.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.4 GO:0019808 polyamine binding(GO:0019808)
0.1 5.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 9.5 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 0.3 GO:0035375 zymogen binding(GO:0035375)
0.0 19.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.8 GO:0004601 peroxidase activity(GO:0004601)
0.0 6.9 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 2.6 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 1.7 GO:0051020 GTPase binding(GO:0051020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 16.9 PID S1P S1P4 PATHWAY S1P4 pathway
1.0 13.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.6 16.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.6 6.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 31.9 PID LKB1 PATHWAY LKB1 signaling events
0.6 24.8 PID ATR PATHWAY ATR signaling pathway
0.6 17.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.5 29.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 11.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 4.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 22.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.3 17.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.3 7.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 13.0 PID ENDOTHELIN PATHWAY Endothelins
0.2 7.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 6.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 1.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 4.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 6.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 4.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.6 PID FOXO PATHWAY FoxO family signaling
0.1 3.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.3 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 56.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
3.3 52.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
2.8 39.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.4 23.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
1.3 15.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
1.2 16.9 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
1.1 59.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
1.0 16.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.9 28.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.8 9.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.8 22.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.7 11.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.7 12.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.7 7.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.6 17.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.6 12.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.6 7.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.5 14.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.5 26.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.4 8.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.4 2.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 6.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 2.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.4 10.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 8.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 6.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 6.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 7.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 5.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 7.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 31.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.2 9.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 2.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 2.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 7.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 3.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 6.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 2.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 0.9 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.7 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 2.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport