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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Cebpe

Z-value: 1.75

Motif logo

Transcription factors associated with Cebpe

Gene Symbol Gene ID Gene Info
ENSRNOG00000014282 CCAAT/enhancer binding protein epsilon

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cebpern6_v1_chr15_-_33358138_33358138-0.044.4e-01Click!

Activity profile of Cebpe motif

Sorted Z-values of Cebpe motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_148119857 101.56 ENSRNOT00000040325
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr14_+_22251499 94.85 ENSRNOT00000087991
ENSRNOT00000002705
UDP glucuronosyltransferase 2 family, polypeptide A1
chr1_-_258875572 89.58 ENSRNOT00000093005
cytochrome P450, family 2, subfamily c, polypeptide 13
chr15_+_57290849 87.59 ENSRNOT00000014909
carboxypeptidase B2
chr19_+_42097995 87.38 ENSRNOT00000020197
haptoglobin
chr14_+_22517774 86.11 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr1_+_147713892 75.21 ENSRNOT00000092985
ENSRNOT00000054742
ENSRNOT00000074103
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
chr4_-_161850875 73.06 ENSRNOT00000009467
pregnancy-zone protein
chr11_-_81639872 68.33 ENSRNOT00000047595
ENSRNOT00000090031
ENSRNOT00000081864
histidine-rich glycoprotein
chr3_-_127500709 64.68 ENSRNOT00000006330
hydroxyacid oxidase 1
chr14_+_22375955 63.19 ENSRNOT00000063915
ENSRNOT00000034784
UDP-glucuronosyltransferase 2 family, member 37
chr3_+_159936856 63.04 ENSRNOT00000078703
hepatocyte nuclear factor 4, alpha
chr3_-_55587946 62.72 ENSRNOT00000075107
ATP binding cassette subfamily B member 11
chr1_-_258766881 60.69 ENSRNOT00000015801
cytochrome P450, family 2, subfamily c, polypeptide 12
chr11_-_81660395 56.03 ENSRNOT00000048739
fetuin B
chr2_+_150146234 55.00 ENSRNOT00000018761
arylacetamide deacetylase
chr11_-_81717521 54.79 ENSRNOT00000058422
alpha-2-HS-glycoprotein
chr4_+_65110746 54.24 ENSRNOT00000017675
aldo-keto reductase family 1, member D1
chr1_+_64506735 53.75 ENSRNOT00000086331
NLR family, pyrin domain containing 12
chr1_+_83711251 53.68 ENSRNOT00000028237
ENSRNOT00000092008
cytochrome P450, family 2, subfamily a, polypeptide 1
chr1_+_83653234 53.67 ENSRNOT00000085008
ENSRNOT00000084230
ENSRNOT00000090071
cytochrome P450, family 2, subfamily a, polypeptide 1
chr2_+_243550627 52.55 ENSRNOT00000085067
ENSRNOT00000083682
alcohol dehydrogenase 1 (class I)
chr1_+_248428099 51.60 ENSRNOT00000050984
mannose binding lectin 2
chr6_-_127534247 50.53 ENSRNOT00000012500
serpin family A member 6
chr3_+_159902441 49.43 ENSRNOT00000089893
ENSRNOT00000011978
hepatocyte nuclear factor 4, alpha
chr14_+_22724399 49.09 ENSRNOT00000002724
UDP glucuronosyltransferase 2 family, polypeptide B10
chr9_+_95256627 48.85 ENSRNOT00000025291
UDP glucuronosyltransferase family 1 member A5
chrX_+_143097525 48.32 ENSRNOT00000004559
coagulation factor IX
chr11_-_81735592 48.16 ENSRNOT00000078203
alpha-2-HS-glycoprotein
chr4_-_50200328 48.11 ENSRNOT00000060530
aminoadipate-semialdehyde synthase
chr1_-_224389389 47.30 ENSRNOT00000077408
ENSRNOT00000050010
integral membrane transport protein UST4r
chr2_+_181987217 45.33 ENSRNOT00000034521
fibrinogen gamma chain
chr1_+_229030233 44.73 ENSRNOT00000084503
glycine-N-acyltransferase-like 1
chr13_+_91080341 44.23 ENSRNOT00000000058
C-reactive protein
chr13_-_56693968 44.12 ENSRNOT00000060160

chr1_+_148240504 43.90 ENSRNOT00000085373
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr16_+_6970342 43.36 ENSRNOT00000061294
ENSRNOT00000048344
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr9_+_9721105 42.78 ENSRNOT00000073042
ENSRNOT00000075494
complement C3
chr11_-_81444375 42.23 ENSRNOT00000058479
ENSRNOT00000078131
ENSRNOT00000080949
ENSRNOT00000080562
ENSRNOT00000084867
kininogen 1
chr2_+_55775274 41.39 ENSRNOT00000018545
complement C9
chr8_-_50531423 41.20 ENSRNOT00000090985
ENSRNOT00000074942
apolipoprotein C3
chr13_+_56598957 38.66 ENSRNOT00000016944
ENSRNOT00000080335
ENSRNOT00000089913
coagulation factor XIII B chain
chr1_+_40086470 38.39 ENSRNOT00000021895
iodotyrosine deiodinase
chr4_-_154855098 38.09 ENSRNOT00000041957
alpha-1-inhibitor III
chr5_-_134484839 37.36 ENSRNOT00000045571
ENSRNOT00000012681
cytochrome P450, family 4, subfamily a, polypeptide 2
chr1_-_258877045 37.12 ENSRNOT00000071633
cytochrome P450, family 2, subfamily c, polypeptide 13
chr12_-_22194287 36.94 ENSRNOT00000082895
ENSRNOT00000001905
transferrin receptor 2
chr9_-_4978892 36.64 ENSRNOT00000015189
sulfotransferase family 1C member 3
chr10_+_96639924 36.55 ENSRNOT00000004756
apolipoprotein H
chr16_+_50152008 35.86 ENSRNOT00000019237
kallikrein B1
chr1_+_229039889 35.73 ENSRNOT00000054800
glycine-N-acyltransferase-like 1
chr1_-_224533219 35.33 ENSRNOT00000051289
integral membrane transport protein UST5r
chr7_+_93975451 35.27 ENSRNOT00000011379
collectin subfamily member 10
chr16_+_18690246 35.13 ENSRNOT00000081484
methionine adenosyltransferase 1A
chr6_+_128050250 34.71 ENSRNOT00000077517
ENSRNOT00000013961
Ab1-233
chr6_-_128003418 34.60 ENSRNOT00000013896
serine (or cysteine) proteinase inhibitor, clade A, member 3C
chr5_-_119564846 34.47 ENSRNOT00000012977
cytochrome P450, family 2, subfamily j, polypeptide 4
chr11_-_66034573 34.17 ENSRNOT00000003645
homogentisate 1, 2-dioxygenase
chr7_-_123630045 33.70 ENSRNOT00000050002
cytochrome P450, family 2, subfamily d, polypeptide 1
chr7_-_3386522 33.52 ENSRNOT00000010760
methyltransferase like 7B
chr13_-_57080491 33.16 ENSRNOT00000017749
ENSRNOT00000086572
ENSRNOT00000060111
complement factor H
chr16_+_18690649 33.03 ENSRNOT00000015190
methionine adenosyltransferase 1A
chr7_-_2677199 32.90 ENSRNOT00000043908
apolipoprotein N
chr1_+_16910069 32.68 ENSRNOT00000020015
aldehyde dehydrogenase 8 family, member A1
chr14_-_19191863 32.57 ENSRNOT00000003921
albumin
chr6_+_127946686 32.19 ENSRNOT00000082680
Ab1-233
chr13_-_80745347 32.11 ENSRNOT00000041908
flavin containing monooxygenase 1
chr12_+_19196611 31.89 ENSRNOT00000001801
alpha-2-glycoprotein 1, zinc-binding
chr9_-_79630452 31.82 ENSRNOT00000078125
ENSRNOT00000086044
ENSRNOT00000089283
peroxisomal trans-2-enoyl-CoA reductase
chr14_+_22937421 31.74 ENSRNOT00000065079
similar to Expressed sequence AI788959
chr6_+_128046780 31.60 ENSRNOT00000078064
Ab1-233
chr14_-_19072677 30.98 ENSRNOT00000060548
similar to alpha-fetoprotein
chr15_+_28028521 30.94 ENSRNOT00000089631

chr19_-_57333433 30.74 ENSRNOT00000024917
angiotensinogen
chr17_+_30556884 30.16 ENSRNOT00000080929
ENSRNOT00000022022
enoyl-CoA delta isomerase 2
chr1_-_259287684 30.01 ENSRNOT00000054724
cytochrome P450, family 2, subfamily c, polypeptide 22
chr19_+_15081590 29.46 ENSRNOT00000024187
carboxylesterase 1F
chr1_+_83744238 29.06 ENSRNOT00000028249
cytochrome P450, family 2, subfamily a, polypeptide 1
chr12_-_19114399 29.05 ENSRNOT00000073099
cytochrome P450, family 3, subfamily a, polypeptide 9
chr2_-_264293010 28.92 ENSRNOT00000082532
ENSRNOT00000067843
cystathionine gamma-lyase
chr7_-_14435967 28.88 ENSRNOT00000074801
peptidoglycan recognition protein 2
chr7_-_123621102 28.41 ENSRNOT00000046024
cytochrome P450, family 2, subfamily d, polypeptide 5
chr14_+_22724070 28.27 ENSRNOT00000089471
UDP glucuronosyltransferase 2 family, polypeptide B10
chr16_+_54164431 27.86 ENSRNOT00000090763
fibrinogen-like 1
chr2_+_104744461 27.68 ENSRNOT00000016083
ENSRNOT00000082627
ceruloplasmin
chr10_-_77512032 27.65 ENSRNOT00000003295
phosphatidylcholine transfer protein
chr6_-_104631355 27.65 ENSRNOT00000007825
solute carrier family 10 member 1
chr7_-_71226150 26.93 ENSRNOT00000005875
similar to Retinol dehydrogenase type II (RODH II) (29 k-protein)
chr5_+_60528997 26.80 ENSRNOT00000051445
glyoxylate and hydroxypyruvate reductase
chr16_+_10267482 26.36 ENSRNOT00000085255
growth differentiation factor 2
chr9_-_4945352 26.33 ENSRNOT00000082530
sulfotransferase family 1C member 3
chr17_-_69460321 26.20 ENSRNOT00000058367
aldo-keto reductase family 1, member C1
chr6_+_80188943 25.76 ENSRNOT00000059335
melanoma inhibitory activity 2
chr15_-_45524582 25.38 ENSRNOT00000081912
guanylate cyclase 1 soluble subunit beta 2
chr2_+_54466280 25.38 ENSRNOT00000033112
complement C6
chr1_-_76722965 25.26 ENSRNOT00000052129
alcohol sulfotransferase-like
chr6_-_7058314 25.15 ENSRNOT00000045996
3-hydroxyanthranilate 3,4-dioxygenase
chr4_-_70659252 25.00 ENSRNOT00000048049
trypsin 10
chr16_+_50179458 24.51 ENSRNOT00000041946
coagulation factor XI
chr6_-_47890033 24.46 ENSRNOT00000011290
collectin sub-family member 11
chr9_+_46962288 24.15 ENSRNOT00000082146
interleukin 1 receptor type 1
chr17_-_69827112 24.02 ENSRNOT00000023835
aldo-keto reductase family 1, member C14
chr11_+_74057361 23.98 ENSRNOT00000048746
carboxypeptidase N subunit 2
chr17_+_8489266 23.90 ENSRNOT00000016252
leukocyte cell-derived chemotaxin 2
chr20_-_30947484 23.56 ENSRNOT00000065614
phosphatase domain containing, paladin 1
chr9_-_19880346 23.53 ENSRNOT00000014051
cytochrome P450, family 39, subfamily a, polypeptide 1
chr15_+_28018040 23.39 ENSRNOT00000041495
ribonuclease A family member 4
chr2_-_164684985 22.89 ENSRNOT00000057504
retinoic acid receptor responder 1
chr11_-_87921679 22.78 ENSRNOT00000084973
serpin family D member 1
chr10_+_64952119 22.47 ENSRNOT00000012154
pipecolic acid and sarcosine oxidase
chr4_+_109497962 21.88 ENSRNOT00000057869
regenerating family member 1 alpha
chr9_+_95161157 21.73 ENSRNOT00000071200
UDP glucuronosyltransferase family 1 member A5
chr4_+_65112944 21.68 ENSRNOT00000083672
aldo-keto reductase family 1, member D1
chr14_-_86190659 21.57 ENSRNOT00000086474
glucokinase
chr6_+_107550904 21.38 ENSRNOT00000013760
acyl-CoA thioesterase 5
chr20_+_40769586 21.16 ENSRNOT00000001079
fatty acid binding protein 7
chr15_+_27875911 21.09 ENSRNOT00000013582
purine nucleoside phosphorylase
chr1_-_222167447 21.06 ENSRNOT00000028687
peroxiredoxin 5
chr14_+_7113544 21.01 ENSRNOT00000038188
hydroxysteroid (17-beta) dehydrogenase 13
chr10_-_38774449 20.85 ENSRNOT00000049820
liver-expressed antimicrobial peptide 2
chr7_-_123655896 20.81 ENSRNOT00000012413
cytochrome P450, family 2, subfamily d, polypeptide 2
chr4_-_23135354 20.76 ENSRNOT00000011432
STEAP4 metalloreductase
chr17_-_69404323 20.64 ENSRNOT00000051342
ENSRNOT00000066282
aldo-keto reductase family 1, member C2
chr20_-_4542073 20.48 ENSRNOT00000000477
complement factor B
chr4_+_98457810 20.40 ENSRNOT00000074175

chr5_+_127770570 20.07 ENSRNOT00000047653
enoyl CoA hydratase domain containing 2
chr6_-_129010271 19.94 ENSRNOT00000075378
serpin family A member 10
chr13_+_78812394 19.94 ENSRNOT00000076043
serpin family C member 1
chr4_-_157155609 19.93 ENSRNOT00000016330
complement C1s
chr9_+_81656116 19.69 ENSRNOT00000083421
solute carrier family 11 member 1
chr7_-_129970550 19.66 ENSRNOT00000055879
megalencephalic leukoencephalopathy with subcortical cysts 1
chr19_+_15094309 19.61 ENSRNOT00000083500
carboxylesterase 1F
chr19_+_15081158 19.52 ENSRNOT00000074070
carboxylesterase 1F
chr9_+_95274707 19.51 ENSRNOT00000045163
UDP glucuronosyltransferase family 1 member A5
chr14_-_44613904 19.50 ENSRNOT00000003811
klotho beta
chr8_+_116857684 19.45 ENSRNOT00000026711
macrophage stimulating 1
chr8_-_111721303 19.41 ENSRNOT00000045628
ENSRNOT00000012725
transferrin
chr5_-_59553416 19.27 ENSRNOT00000090490
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr14_+_2050483 18.78 ENSRNOT00000000047
solute carrier family 26 member 1
chr13_+_103396314 18.76 ENSRNOT00000049499
solute carrier family 30, member 10
chr14_-_19132208 18.32 ENSRNOT00000060535
afamin
chrX_+_25016401 18.28 ENSRNOT00000059270
chloride voltage-gated channel 4
chr3_+_5519990 18.27 ENSRNOT00000070873
ENSRNOT00000007640
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr5_+_61425746 18.23 ENSRNOT00000064113
hypothetical LOC298077
chr17_+_22620721 18.04 ENSRNOT00000019478
androgen-dependent TFPI-regulating protein
chrX_+_152933069 17.81 ENSRNOT00000091154
NAD(P) dependent steroid dehydrogenase-like
chr17_+_22619891 17.76 ENSRNOT00000060403
androgen-dependent TFPI-regulating protein
chr12_+_18679789 17.60 ENSRNOT00000001863
cytochrome P450, family 3, subfamily a, polypeptide 9
chr3_-_48372583 17.50 ENSRNOT00000040482
ENSRNOT00000077788
ENSRNOT00000085426
dipeptidylpeptidase 4
chr11_+_65022100 17.46 ENSRNOT00000003934
nuclear receptor subfamily 1, group I, member 2
chr13_-_111972603 17.35 ENSRNOT00000007870
hydroxysteroid 11-beta dehydrogenase 1
chr2_+_222214885 17.35 ENSRNOT00000055723
dihydropyrimidine dehydrogenase
chr17_+_69468427 17.31 ENSRNOT00000058413
similar to 20-alpha-hydroxysteroid dehydrogenase
chr4_-_176679815 17.14 ENSRNOT00000090122
glycogen synthase 2
chr2_-_233743866 17.10 ENSRNOT00000087062
glutamyl aminopeptidase
chr19_+_15339152 16.97 ENSRNOT00000060929
carboxylesterase 1A
chr7_-_27552078 16.88 ENSRNOT00000059538
stabilin 2
chr18_-_35071619 16.83 ENSRNOT00000075695
serine protease inhibitor Kazal-type 3-like
chr13_+_83073544 16.61 ENSRNOT00000066119
ENSRNOT00000079796
ENSRNOT00000077070
dermatopontin
chr14_-_80973456 16.50 ENSRNOT00000013257
HGF activator
chr3_+_54253949 16.49 ENSRNOT00000010018
Beta-1,3-galactosyltransferase 1
chr9_+_95202632 16.44 ENSRNOT00000025652
UDP glucuronosyltransferase family 1 member A5
chr7_+_28412198 16.38 ENSRNOT00000081822
ENSRNOT00000038780
ENSRNOT00000005995
insulin-like growth factor 1
chr14_-_19159923 15.91 ENSRNOT00000003879
alpha-fetoprotein
chr1_+_167937026 15.83 ENSRNOT00000020655
olfactory receptor 57
chr17_+_76002275 15.82 ENSRNOT00000092665
ENSRNOT00000086701
enoyl CoA hydratase domain containing 3
chr1_+_166428761 15.71 ENSRNOT00000085555
StAR-related lipid transfer domain containing 10
chr7_+_70980422 15.68 ENSRNOT00000077912
retinol dehydrogenase 16 (all-trans)
chr8_+_117117430 15.58 ENSRNOT00000073247
glutathione peroxidase 1
chr4_+_70776046 15.52 ENSRNOT00000040403
protease, serine 1
chr9_+_4107246 15.42 ENSRNOT00000078212

chr10_+_64737022 15.17 ENSRNOT00000017071
ENSRNOT00000093232
ENSRNOT00000017042
ENSRNOT00000093244
galectin 9
chr4_+_157126935 15.12 ENSRNOT00000056051
complement C1r
chr13_+_91481461 15.07 ENSRNOT00000012103
olfactory receptor 1576
chr20_-_4070721 15.04 ENSRNOT00000000523
RT1 class II, locus Ba
chr4_-_30556814 15.02 ENSRNOT00000012760
pyruvate dehydrogenase kinase 4
chr2_-_181905300 14.95 ENSRNOT00000035411
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
chr7_+_101069104 14.94 ENSRNOT00000056894

chr11_-_80981415 14.84 ENSRNOT00000002499
ENSRNOT00000002496
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr5_-_77749613 14.80 ENSRNOT00000075988
major urinary protein 5
chr1_+_282638017 14.68 ENSRNOT00000079722
ENSRNOT00000082254
carboxylesterase 2C
chr7_+_71057911 14.61 ENSRNOT00000037218
retinol dehydrogenase 16 (all-trans)
chr3_-_76518601 14.52 ENSRNOT00000071021
olfactory receptor 623
chr1_+_282694906 14.39 ENSRNOT00000074303
carboxylesterase 2C
chr13_+_83073866 14.38 ENSRNOT00000075996
dermatopontin
chr5_+_135536413 14.36 ENSRNOT00000023132
peroxiredoxin 1
chr4_-_123557501 14.13 ENSRNOT00000075042
ENSRNOT00000085966
aldehyde dehydrogenase 1 family, member L1
chr10_+_104368247 14.13 ENSRNOT00000006519
LLGL2, scribble cell polarity complex component
chr9_+_81968332 14.08 ENSRNOT00000023152
cytochrome P450, family 27, subfamily a, polypeptide 1
chr4_+_70755795 14.04 ENSRNOT00000043527
similar to Anionic trypsin II precursor (Pretrypsinogen II)
chr14_+_84274550 13.95 ENSRNOT00000006053
ENSRNOT00000087383
SEC14-like lipid binding 4
chr7_+_28414350 13.92 ENSRNOT00000085680
insulin-like growth factor 1
chr1_-_251338358 13.88 ENSRNOT00000002054
cytochrome P450, family 2, subfamily b, polypeptide 15
chr15_-_19733967 13.86 ENSRNOT00000012036
glucosamine-phosphate N-acetyltransferase 1
chr10_-_98390384 13.73 ENSRNOT00000065947
ATP-binding cassette, subfamily A (ABC1), member 8a
chr1_-_189181901 13.72 ENSRNOT00000092022
glycoprotein 2
chr17_+_79749747 13.70 ENSRNOT00000081743

chr5_+_154294806 13.58 ENSRNOT00000012853
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr5_+_160306727 13.57 ENSRNOT00000016648
agmatinase
chr13_-_99287887 13.53 ENSRNOT00000004780
epoxide hydrolase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Cebpe

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
39.4 118.3 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
32.0 128.2 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
29.1 87.4 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
28.1 112.5 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
22.8 68.3 GO:0097037 heme export(GO:0097037)
22.5 607.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
18.1 54.4 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
17.9 53.8 GO:0008592 regulation of Toll signaling pathway(GO:0008592) negative regulation of Toll signaling pathway(GO:0045751)
17.6 70.6 GO:0019477 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
17.5 52.6 GO:0006117 acetaldehyde metabolic process(GO:0006117)
16.2 64.7 GO:0009441 glycolate metabolic process(GO:0009441)
15.9 206.2 GO:0052695 cellular glucuronidation(GO:0052695)
15.1 60.2 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
14.1 56.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
13.7 41.2 GO:0010982 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) regulation of high-density lipoprotein particle clearance(GO:0010982)
13.6 68.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
11.7 23.5 GO:0055073 cadmium ion homeostasis(GO:0055073)
11.7 46.7 GO:0002933 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
11.4 34.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
10.6 31.8 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
10.5 41.9 GO:0048252 lauric acid metabolic process(GO:0048252)
9.7 87.4 GO:0046618 drug export(GO:0046618)
9.6 28.9 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
9.3 28.0 GO:1990743 protein sialylation(GO:1990743)
9.3 9.3 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
9.0 63.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
8.6 60.4 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
8.2 32.9 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
7.9 102.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
7.6 30.3 GO:0001834 trophectodermal cell proliferation(GO:0001834)
7.4 44.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
7.3 21.9 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
7.2 35.9 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
7.1 21.4 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
7.1 28.5 GO:0032824 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
7.0 21.1 GO:0034418 nicotinamide riboside catabolic process(GO:0006738) urate biosynthetic process(GO:0034418) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
6.9 55.0 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
6.7 6.7 GO:0015920 lipopolysaccharide transport(GO:0015920)
6.4 19.3 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
6.3 18.8 GO:0071579 regulation of zinc ion transport(GO:0071579)
6.2 62.2 GO:0070995 NADPH oxidation(GO:0070995)
6.2 61.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
6.1 18.2 GO:0046864 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
5.8 17.5 GO:0061744 motor behavior(GO:0061744)
5.8 17.3 GO:0046127 thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
5.8 17.3 GO:0006713 glucocorticoid catabolic process(GO:0006713)
5.7 45.3 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
5.6 72.6 GO:0006570 tyrosine metabolic process(GO:0006570)
5.5 22.2 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
5.5 27.7 GO:0015679 plasma membrane copper ion transport(GO:0015679)
5.4 32.6 GO:0001907 killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004) response to platinum ion(GO:0070541)
5.3 47.5 GO:0015747 urate transport(GO:0015747)
5.2 15.6 GO:0009609 response to symbiotic bacterium(GO:0009609)
4.7 108.6 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
4.7 14.1 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
4.7 14.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
4.6 23.0 GO:0002003 angiotensin maturation(GO:0002003)
4.5 13.4 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
4.3 8.7 GO:0070839 divalent metal ion export(GO:0070839)
4.3 21.6 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
4.3 25.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
4.2 12.5 GO:0014016 neuroblast differentiation(GO:0014016)
4.0 32.3 GO:0042738 exogenous drug catabolic process(GO:0042738)
3.8 15.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
3.6 10.9 GO:0042412 taurine biosynthetic process(GO:0042412)
3.5 14.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
3.4 6.9 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
3.4 13.6 GO:0046951 ketone body biosynthetic process(GO:0046951)
3.2 16.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
3.1 9.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
3.1 12.5 GO:0001579 medium-chain fatty acid transport(GO:0001579)
3.1 6.1 GO:0042223 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
3.0 32.7 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
2.9 5.7 GO:0009608 response to symbiont(GO:0009608)
2.9 11.5 GO:0035772 interleukin-13-mediated signaling pathway(GO:0035772)
2.8 19.5 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
2.7 8.2 GO:0014916 regulation of lung blood pressure(GO:0014916)
2.7 13.6 GO:0008295 spermidine biosynthetic process(GO:0008295)
2.7 8.1 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
2.7 8.0 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
2.6 66.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
2.6 10.5 GO:0002084 protein depalmitoylation(GO:0002084)
2.6 7.8 GO:2000978 gastrin-induced gastric acid secretion(GO:0001698) positive regulation of actin filament-based movement(GO:1903116) negative regulation of forebrain neuron differentiation(GO:2000978)
2.6 20.8 GO:0015677 copper ion import(GO:0015677)
2.6 25.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
2.6 23.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
2.5 7.6 GO:0048749 compound eye development(GO:0048749)
2.5 7.6 GO:0033076 isoquinoline alkaloid metabolic process(GO:0033076) phytoalexin metabolic process(GO:0052314)
2.5 17.7 GO:0047484 regulation of response to osmotic stress(GO:0047484)
2.5 35.4 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
2.5 67.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
2.5 57.5 GO:0008211 glucocorticoid metabolic process(GO:0008211)
2.4 7.3 GO:0006552 leucine catabolic process(GO:0006552)
2.4 7.3 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
2.4 16.7 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
2.4 21.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
2.3 7.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
2.3 46.3 GO:0035634 response to stilbenoid(GO:0035634)
2.3 13.9 GO:0006041 glucosamine metabolic process(GO:0006041)
2.2 6.7 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
2.2 2.2 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
2.2 10.9 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
2.2 10.8 GO:0009758 carbohydrate utilization(GO:0009758)
2.2 12.9 GO:0008050 female courtship behavior(GO:0008050)
2.1 8.5 GO:1990375 baculum development(GO:1990375)
2.1 10.6 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
2.1 17.0 GO:0042448 progesterone metabolic process(GO:0042448)
2.1 10.4 GO:0009115 xanthine catabolic process(GO:0009115)
2.1 6.2 GO:2000502 stimulatory C-type lectin receptor signaling pathway(GO:0002223) negative regulation of natural killer cell chemotaxis(GO:2000502)
2.0 5.9 GO:2000424 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
2.0 5.9 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
2.0 2.0 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
1.9 15.0 GO:0006776 vitamin A metabolic process(GO:0006776)
1.8 86.9 GO:0006953 acute-phase response(GO:0006953)
1.8 7.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
1.7 10.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
1.7 5.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
1.7 6.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.7 11.6 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.7 48.0 GO:0019369 arachidonic acid metabolic process(GO:0019369)
1.6 6.6 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
1.6 4.9 GO:0046968 cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
1.6 4.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
1.6 8.1 GO:0006741 NADP biosynthetic process(GO:0006741)
1.6 4.8 GO:1901423 response to benzene(GO:1901423)
1.6 6.4 GO:1902896 terminal web assembly(GO:1902896)
1.6 11.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
1.6 8.0 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
1.6 3.2 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
1.6 4.7 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350) regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
1.5 26.2 GO:0006662 glycerol ether metabolic process(GO:0006662)
1.5 4.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
1.5 59.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
1.5 4.5 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.5 13.3 GO:0071494 cellular response to UV-C(GO:0071494)
1.5 10.2 GO:0038161 prolactin signaling pathway(GO:0038161)
1.4 5.6 GO:0019516 lactate oxidation(GO:0019516)
1.4 7.0 GO:0001757 somite specification(GO:0001757)
1.4 8.3 GO:0010041 response to iron(III) ion(GO:0010041) response to anoxia(GO:0034059)
1.4 5.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
1.4 22.1 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
1.4 2.7 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
1.4 12.3 GO:0034312 diol biosynthetic process(GO:0034312)
1.4 6.8 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
1.3 4.0 GO:0006574 valine catabolic process(GO:0006574)
1.3 5.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
1.3 5.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.3 5.0 GO:0006004 fucose metabolic process(GO:0006004)
1.2 13.7 GO:0043983 histone H4-K12 acetylation(GO:0043983)
1.2 67.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
1.2 19.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
1.2 29.1 GO:0042168 heme metabolic process(GO:0042168)
1.2 10.7 GO:0006983 ER overload response(GO:0006983)
1.2 7.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
1.2 7.0 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
1.1 3.4 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
1.1 15.6 GO:0060046 regulation of acrosome reaction(GO:0060046)
1.1 15.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
1.1 3.2 GO:0035565 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
1.0 3.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
1.0 8.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
1.0 7.2 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071) negative regulation of nuclease activity(GO:0032074)
1.0 3.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
1.0 2.0 GO:0072717 response to actinomycin D(GO:0072716) cellular response to actinomycin D(GO:0072717)
1.0 10.2 GO:0006465 signal peptide processing(GO:0006465)
1.0 30.3 GO:0071353 cellular response to interleukin-4(GO:0071353)
1.0 15.1 GO:0006956 complement activation(GO:0006956)
1.0 8.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
1.0 6.9 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
1.0 3.0 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
1.0 3.9 GO:0050913 sensory perception of bitter taste(GO:0050913)
1.0 9.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
1.0 15.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
1.0 12.5 GO:0006855 drug transmembrane transport(GO:0006855)
1.0 1.0 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.9 54.8 GO:0007566 embryo implantation(GO:0007566)
0.9 4.7 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803)
0.9 27.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.9 5.3 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.9 4.4 GO:0070202 regulation of establishment of protein localization to chromosome(GO:0070202)
0.9 8.7 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.9 2.6 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.9 6.9 GO:0015866 ADP transport(GO:0015866) ATP transport(GO:0015867)
0.9 5.2 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.9 14.6 GO:1902358 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.9 6.8 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.9 11.9 GO:0042407 cristae formation(GO:0042407)
0.8 7.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.8 5.9 GO:0034214 protein hexamerization(GO:0034214)
0.8 4.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686) generation of ovulation cycle rhythm(GO:0060112)
0.8 3.3 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.8 2.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.8 1049.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.8 7.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.8 6.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.8 17.8 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.8 4.0 GO:0035627 ceramide transport(GO:0035627)
0.8 5.6 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.8 5.5 GO:0070269 pyroptosis(GO:0070269)
0.8 11.0 GO:0015693 magnesium ion transport(GO:0015693)
0.8 6.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.8 14.1 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.8 3.1 GO:0019042 viral latency(GO:0019042) release from viral latency(GO:0019046)
0.8 1.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.7 14.9 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.7 0.7 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.7 5.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.7 2.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.7 2.2 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.7 11.8 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.7 12.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.7 9.3 GO:0034063 stress granule assembly(GO:0034063)
0.7 2.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.7 3.6 GO:0050916 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582) sensory perception of sweet taste(GO:0050916)
0.7 6.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.7 2.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.7 2.0 GO:0032365 intracellular lipid transport(GO:0032365) intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.7 10.2 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.7 6.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.7 2.0 GO:0072679 thymocyte migration(GO:0072679)
0.7 2.7 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.7 2.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.7 2.0 GO:0036258 multivesicular body assembly(GO:0036258) negative regulation of exosomal secretion(GO:1903542)
0.7 2.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.7 20.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.6 9.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.6 14.2 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.6 1.9 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.6 2.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.6 3.8 GO:0051182 coenzyme transport(GO:0051182)
0.6 4.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.6 3.7 GO:0071918 urea transmembrane transport(GO:0071918)
0.6 2.4 GO:0036166 DNA methylation on cytosine within a CG sequence(GO:0010424) phenotypic switching(GO:0036166)
0.6 4.9 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.6 28.0 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.6 1.8 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.6 2.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.6 20.1 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.6 2.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.6 1.8 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.6 5.9 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.6 6.4 GO:0015671 oxygen transport(GO:0015671)
0.6 2.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.6 3.5 GO:0071318 cellular response to ATP(GO:0071318)
0.6 6.3 GO:0006491 N-glycan processing(GO:0006491)
0.6 4.0 GO:0032790 ribosome disassembly(GO:0032790)
0.6 5.0 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.6 1.7 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.5 13.4 GO:0051180 vitamin transport(GO:0051180)
0.5 3.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.5 3.1 GO:2001271 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.5 4.6 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.5 1.5 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.5 4.5 GO:0045059 positive regulation of T cell differentiation in thymus(GO:0033089) positive thymic T cell selection(GO:0045059) positive regulation of thymocyte aggregation(GO:2000400)
0.5 17.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.5 7.5 GO:0009062 fatty acid catabolic process(GO:0009062)
0.5 75.6 GO:0007596 blood coagulation(GO:0007596)
0.5 12.3 GO:0097502 mannosylation(GO:0097502)
0.5 7.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.5 12.4 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.5 3.8 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.5 4.7 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.5 30.3 GO:0022904 respiratory electron transport chain(GO:0022904)
0.5 1.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.5 3.2 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.5 1.8 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.5 4.5 GO:0042574 retinal metabolic process(GO:0042574)
0.5 2.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.4 1.3 GO:0036451 cap mRNA methylation(GO:0036451)
0.4 1.3 GO:0033197 response to vitamin E(GO:0033197)
0.4 10.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.4 4.8 GO:0071420 cellular response to histamine(GO:0071420)
0.4 15.8 GO:0030199 collagen fibril organization(GO:0030199)
0.4 1.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.4 3.0 GO:0030916 otic vesicle formation(GO:0030916)
0.4 2.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.4 1.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.4 0.8 GO:0046687 response to chromate(GO:0046687)
0.4 1.2 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.4 2.0 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.4 3.9 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.4 2.7 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.4 3.5 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.4 2.3 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.4 4.9 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.4 26.8 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.4 0.8 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.4 6.7 GO:0070166 enamel mineralization(GO:0070166)
0.4 0.7 GO:0072162 metanephric mesenchymal cell differentiation(GO:0072162)
0.4 2.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 1.5 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.4 4.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.4 1.4 GO:0030222 eosinophil differentiation(GO:0030222)
0.4 1.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 5.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.3 3.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 17.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.3 27.3 GO:0016125 sterol metabolic process(GO:0016125)
0.3 2.0 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 1.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.3 3.6 GO:0051764 actin crosslink formation(GO:0051764)
0.3 2.3 GO:0060613 fat pad development(GO:0060613)
0.3 0.6 GO:1904009 response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
0.3 5.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3 7.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 4.3 GO:0051451 myoblast migration(GO:0051451)
0.3 0.9 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.3 0.6 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.3 0.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 3.5 GO:0006517 protein deglycosylation(GO:0006517)
0.3 2.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 5.8 GO:0019835 cytolysis(GO:0019835)
0.3 2.0 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.3 2.6 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.3 2.6 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.3 1.4 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.3 3.1 GO:0032275 luteinizing hormone secretion(GO:0032275)
0.3 24.8 GO:0007586 digestion(GO:0007586)
0.3 0.8 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.3 2.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 2.1 GO:0002517 T cell tolerance induction(GO:0002517)
0.3 1.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 5.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.3 2.0 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 2.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 2.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.2 1.7 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.2 1.0 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.2 0.7 GO:1904796 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.2 4.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 1.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 0.9 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.2 1.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 2.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.2 1.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 1.7 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 1.9 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.2 2.9 GO:0005513 detection of calcium ion(GO:0005513)
0.2 3.2 GO:0006541 glutamine metabolic process(GO:0006541)
0.2 3.4 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.2 1.2 GO:0051775 response to redox state(GO:0051775)
0.2 3.8 GO:0060416 response to growth hormone(GO:0060416)
0.2 2.0 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 5.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 0.6 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 1.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2 4.2 GO:0006739 NADP metabolic process(GO:0006739)
0.2 1.1 GO:0097490 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.2 4.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 2.1 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.2 0.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 3.5 GO:2000772 regulation of cellular senescence(GO:2000772)
0.2 6.3 GO:0032543 mitochondrial translation(GO:0032543)
0.2 1.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 3.1 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.2 2.7 GO:0021554 optic nerve development(GO:0021554)
0.2 6.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 1.0 GO:2001204 regulation of osteoclast development(GO:2001204)
0.2 4.8 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.2 1.4 GO:0072718 response to cisplatin(GO:0072718)
0.2 1.0 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.2 4.4 GO:0018149 peptide cross-linking(GO:0018149)
0.2 0.9 GO:0080009 mRNA methylation(GO:0080009)
0.2 0.3 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.2 24.4 GO:0006790 sulfur compound metabolic process(GO:0006790)
0.2 10.3 GO:0014823 response to activity(GO:0014823)
0.2 2.6 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 1.6 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.3 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 1.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 0.4 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) ureter development(GO:0072189)
0.1 23.2 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 0.6 GO:0048318 protein O-linked glycosylation via serine(GO:0018242) axial mesoderm development(GO:0048318)
0.1 0.8 GO:0035745 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.1 1.6 GO:2000757 negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.1 0.4 GO:0046886 positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.1 4.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 13.2 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.1 0.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 3.6 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 0.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 1.7 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 1.9 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.1 2.4 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.1 1.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.5 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.1 1.0 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.7 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.1 0.5 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.2 GO:0018065 protein lipoylation(GO:0009249) protein-cofactor linkage(GO:0018065)
0.1 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.1 GO:0009189 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 0.5 GO:0009629 response to gravity(GO:0009629)
0.1 1.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 1.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 2.7 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.2 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.8 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0032197 transposition, RNA-mediated(GO:0032197)
0.0 0.5 GO:0019395 fatty acid oxidation(GO:0019395)
0.0 1.8 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.9 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.3 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 14.5 GO:0055114 oxidation-reduction process(GO:0055114)
0.0 0.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0097186 amelogenesis(GO:0097186)
0.0 0.1 GO:0051593 response to folic acid(GO:0051593)
0.0 0.5 GO:1903557 positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557)
0.0 0.1 GO:0015697 quaternary ammonium group transport(GO:0015697)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
21.8 87.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
17.1 68.3 GO:0061474 phagolysosome membrane(GO:0061474)
10.6 63.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
10.3 41.4 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
7.9 103.1 GO:0046581 intercellular canaliculus(GO:0046581)
7.8 23.5 GO:0070821 tertiary granule membrane(GO:0070821)
6.9 41.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
6.1 30.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
5.7 45.3 GO:0005577 fibrinogen complex(GO:0005577)
5.2 36.5 GO:0042627 chylomicron(GO:0042627)
5.1 25.4 GO:0005579 membrane attack complex(GO:0005579)
4.3 12.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
4.3 468.8 GO:0072562 blood microparticle(GO:0072562)
3.6 71.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
3.1 9.4 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
3.1 15.6 GO:0097413 Lewy body(GO:0097413)
3.1 28.0 GO:0000138 Golgi trans cisterna(GO:0000138)
2.8 13.8 GO:0072557 IPAF inflammasome complex(GO:0072557)
2.4 38.6 GO:0042613 MHC class II protein complex(GO:0042613)
2.1 6.2 GO:0071942 XPC complex(GO:0071942)
2.0 5.9 GO:0033165 interphotoreceptor matrix(GO:0033165)
1.7 7.0 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
1.7 11.9 GO:0061617 MICOS complex(GO:0061617)
1.7 10.0 GO:0097209 epidermal lamellar body(GO:0097209)
1.6 8.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.6 7.8 GO:1990769 proximal neuron projection(GO:1990769)
1.5 6.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
1.5 107.2 GO:0005581 collagen trimer(GO:0005581)
1.4 92.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
1.4 6.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.3 17.1 GO:0031983 vesicle lumen(GO:0031983)
1.3 3.9 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
1.3 20.7 GO:0045180 basal cortex(GO:0045180)
1.3 24.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.3 21.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.2 970.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
1.2 4.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.1 9.7 GO:0042587 glycogen granule(GO:0042587)
1.1 6.4 GO:1990357 terminal web(GO:1990357)
1.1 25.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.1 9.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.0 9.3 GO:0005826 actomyosin contractile ring(GO:0005826)
1.0 138.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
1.0 17.2 GO:0045277 respiratory chain complex IV(GO:0045277)
1.0 3.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.9 2.8 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.9 9.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.9 6.4 GO:0005833 hemoglobin complex(GO:0005833)
0.9 7.3 GO:0097452 GAIT complex(GO:0097452)
0.8 4.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.8 2.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.8 3.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.8 10.5 GO:0032426 stereocilium tip(GO:0032426)
0.7 4.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.7 1.4 GO:0098576 extrinsic component of Golgi membrane(GO:0090498) lumenal side of membrane(GO:0098576)
0.7 3.6 GO:1903767 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
0.7 6.9 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.7 2.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.7 33.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.7 9.9 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.6 5.1 GO:0061700 GATOR2 complex(GO:0061700)
0.6 18.0 GO:0008305 integrin complex(GO:0008305)
0.6 2.5 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.6 25.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.6 1.8 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.6 20.3 GO:0032590 dendrite membrane(GO:0032590)
0.6 8.4 GO:0030061 mitochondrial crista(GO:0030061)
0.6 2.2 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.5 2.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.5 7.0 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.5 691.4 GO:0005615 extracellular space(GO:0005615)
0.5 6.6 GO:0000801 central element(GO:0000801)
0.5 4.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.5 4.4 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.5 31.3 GO:0045095 keratin filament(GO:0045095)
0.5 0.9 GO:0070939 Dsl1p complex(GO:0070939)
0.5 12.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.5 22.0 GO:0005811 lipid particle(GO:0005811)
0.4 5.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 18.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.4 16.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.4 1.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 42.6 GO:0016363 nuclear matrix(GO:0016363)
0.4 5.3 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.4 10.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.3 1.3 GO:0035061 interchromatin granule(GO:0035061)
0.3 1.3 GO:0045098 type III intermediate filament(GO:0045098)
0.3 8.7 GO:0005921 gap junction(GO:0005921)
0.3 0.9 GO:0097543 ciliary inversin compartment(GO:0097543)
0.3 1.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 1.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 2.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 62.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 1.7 GO:0070847 core mediator complex(GO:0070847)
0.3 2.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.3 1.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 22.1 GO:0005901 caveola(GO:0005901)
0.3 4.4 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.3 3.8 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.3 0.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 1.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 3.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.3 1.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 4.1 GO:0042629 mast cell granule(GO:0042629)
0.2 1.6 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.6 GO:0042101 T cell receptor complex(GO:0042101)
0.2 1.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 2.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 48.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 5.7 GO:0031526 brush border membrane(GO:0031526)
0.2 1.5 GO:0030870 Mre11 complex(GO:0030870)
0.2 210.0 GO:0005739 mitochondrion(GO:0005739)
0.2 0.8 GO:0031417 NatC complex(GO:0031417)
0.2 3.1 GO:0000502 proteasome complex(GO:0000502)
0.2 1.1 GO:0070449 elongin complex(GO:0070449)
0.2 2.7 GO:0032039 integrator complex(GO:0032039)
0.2 7.8 GO:0005844 polysome(GO:0005844)
0.2 1.2 GO:0032009 early phagosome(GO:0032009)
0.2 0.3 GO:0030689 Noc complex(GO:0030689)
0.2 0.9 GO:0036396 MIS complex(GO:0036396)
0.1 1.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 2.2 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 43.9 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.0 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 2.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.8 GO:0005683 U7 snRNP(GO:0005683)
0.1 3.9 GO:0005604 basement membrane(GO:0005604)
0.1 2.0 GO:0045120 pronucleus(GO:0045120)
0.1 11.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 11.0 GO:0055037 recycling endosome(GO:0055037)
0.1 2.7 GO:0016235 aggresome(GO:0016235)
0.1 5.4 GO:0005802 trans-Golgi network(GO:0005802)
0.1 5.8 GO:0032432 actin filament bundle(GO:0032432)
0.1 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 2.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 3.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 227.8 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.3 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0032806 carboxy-terminal domain protein kinase complex(GO:0032806)
0.0 63.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 1.0 GO:0098791 Golgi subcompartment(GO:0098791)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
27.8 83.5 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
25.7 102.9 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
23.9 71.8 GO:0008405 arachidonic acid 11,12-epoxygenase activity(GO:0008405)
23.6 70.9 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
22.7 68.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
21.2 572.5 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
16.2 64.7 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973)
15.7 63.0 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
14.8 459.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
14.6 73.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
14.3 42.8 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
13.7 41.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
13.4 80.5 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
12.2 36.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
11.4 34.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
10.7 75.1 GO:0030492 hemoglobin binding(GO:0030492)
10.3 51.6 GO:0005534 galactose binding(GO:0005534)
9.8 118.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
8.9 35.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
8.8 52.6 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
8.2 24.6 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
8.2 90.3 GO:0001846 opsonin binding(GO:0001846)
8.0 31.8 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
7.5 30.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
7.3 29.1 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
7.1 114.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
7.1 28.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
7.0 21.1 GO:0002060 purine nucleobase binding(GO:0002060) purine-nucleoside phosphorylase activity(GO:0004731)
7.0 28.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
6.6 26.3 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
6.4 19.3 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
6.3 12.6 GO:0019238 cyclohydrolase activity(GO:0019238)
5.8 17.3 GO:0004159 dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
5.8 17.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
5.7 141.5 GO:0070330 aromatase activity(GO:0070330)
5.6 22.5 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
5.2 25.8 GO:0042954 lipoprotein transporter activity(GO:0042954)
4.8 47.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
4.7 32.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
4.6 27.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
4.6 27.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
4.3 51.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
4.2 12.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
4.2 12.5 GO:0008458 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
3.9 23.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
3.9 34.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
3.8 15.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
3.7 22.0 GO:0048030 disaccharide binding(GO:0048030)
3.6 10.8 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
3.6 21.6 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
3.5 10.6 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
3.5 20.8 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
3.4 24.0 GO:0004064 arylesterase activity(GO:0004064)
3.4 13.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
3.4 10.2 GO:0004925 prolactin receptor activity(GO:0004925)
3.4 36.9 GO:0039706 co-receptor binding(GO:0039706)
3.4 80.6 GO:0019865 immunoglobulin binding(GO:0019865)
3.3 13.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
3.3 13.2 GO:0004594 pantothenate kinase activity(GO:0004594)
3.1 9.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
3.1 62.6 GO:0019825 oxygen binding(GO:0019825)
3.1 37.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
3.1 12.4 GO:0055100 adiponectin binding(GO:0055100)
3.1 30.7 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
3.0 17.8 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
3.0 5.9 GO:0000253 3-keto sterol reductase activity(GO:0000253)
2.9 8.7 GO:0001847 opsonin receptor activity(GO:0001847)
2.9 57.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
2.8 31.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
2.8 55.0 GO:0004806 triglyceride lipase activity(GO:0004806)
2.7 13.5 GO:0004301 epoxide hydrolase activity(GO:0004301)
2.7 8.1 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
2.7 26.8 GO:0070402 NADPH binding(GO:0070402)
2.7 26.7 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
2.7 5.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
2.7 13.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
2.6 49.0 GO:0005537 mannose binding(GO:0005537)
2.6 38.4 GO:0010181 FMN binding(GO:0010181)
2.5 7.6 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
2.5 7.6 GO:0004167 dopachrome isomerase activity(GO:0004167)
2.5 279.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
2.5 29.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
2.5 34.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
2.5 17.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
2.5 12.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
2.4 7.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
2.4 7.3 GO:0004827 proline-tRNA ligase activity(GO:0004827)
2.3 9.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
2.2 22.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
2.1 6.4 GO:0004956 prostaglandin D receptor activity(GO:0004956)
2.1 16.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
2.0 10.1 GO:0032052 bile acid binding(GO:0032052)
2.0 8.0 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
2.0 21.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
1.9 5.6 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
1.8 12.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
1.8 39.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
1.8 5.3 GO:0001069 regulatory region RNA binding(GO:0001069)
1.7 3.4 GO:0019767 IgE receptor activity(GO:0019767)
1.7 8.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
1.7 5.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
1.6 4.9 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
1.6 19.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
1.6 14.5 GO:0019841 retinol binding(GO:0019841)
1.6 4.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.6 3.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
1.6 4.7 GO:0042806 fucose binding(GO:0042806)
1.6 7.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
1.6 6.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.5 5.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
1.4 5.7 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
1.4 34.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.4 38.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.4 9.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.4 5.5 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
1.4 17.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
1.3 6.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
1.3 9.1 GO:0045340 mercury ion binding(GO:0045340)
1.3 14.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
1.3 3.8 GO:0051185 coenzyme transporter activity(GO:0051185)
1.3 10.1 GO:0008172 S-methyltransferase activity(GO:0008172)
1.2 17.4 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.2 10.0 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.2 6.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
1.2 6.2 GO:0035473 lipase binding(GO:0035473)
1.2 5.9 GO:0015252 hydrogen ion channel activity(GO:0015252)
1.2 5.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
1.2 245.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.1 95.9 GO:0003823 antigen binding(GO:0003823)
1.1 453.2 GO:0005549 odorant binding(GO:0005549)
1.1 7.6 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
1.1 4.4 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995) TFIIIC-class transcription factor binding(GO:0001156)
1.1 11.9 GO:0070513 death domain binding(GO:0070513)
1.0 26.2 GO:0004383 guanylate cyclase activity(GO:0004383)
1.0 13.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.0 30.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.0 4.0 GO:0016289 CoA hydrolase activity(GO:0016289)
1.0 14.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.0 2.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.0 2.9 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
1.0 2.9 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
1.0 4.8 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.9 10.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.9 2.8 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.9 7.4 GO:0016421 CoA carboxylase activity(GO:0016421)
0.9 3.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.9 7.3 GO:0051525 mitogen-activated protein kinase p38 binding(GO:0048273) NFAT protein binding(GO:0051525)
0.9 18.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.9 1.8 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.9 3.5 GO:0046790 virion binding(GO:0046790)
0.9 7.0 GO:0070700 BMP receptor binding(GO:0070700)
0.9 6.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.9 2.6 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.9 5.1 GO:0070728 leucine binding(GO:0070728)
0.8 20.1 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.8 4.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.8 3.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.8 13.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.8 27.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.8 6.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.8 19.9 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.8 7.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.7 2.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.7 17.5 GO:0008527 taste receptor activity(GO:0008527)
0.7 2.1 GO:0001605 adrenomedullin receptor activity(GO:0001605)
0.7 18.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.7 6.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.7 10.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.7 2.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.7 5.5 GO:0016805 dipeptidase activity(GO:0016805)
0.7 2.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.7 4.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.7 6.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.7 21.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.7 3.3 GO:0005148 prolactin receptor binding(GO:0005148)
0.7 3.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.7 7.8 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.6 2.6 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.6 557.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.6 3.0 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.6 1.8 GO:0047708 biotinidase activity(GO:0047708)
0.6 10.5 GO:0070628 proteasome binding(GO:0070628)
0.6 5.2 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.6 3.5 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.6 7.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.6 6.7 GO:0051787 misfolded protein binding(GO:0051787)
0.6 8.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.6 3.9 GO:0097001 ceramide binding(GO:0097001)
0.5 10.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.5 67.4 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.5 3.7 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.5 1.6 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.5 14.4 GO:0005504 fatty acid binding(GO:0005504)
0.5 37.8 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.5 24.3 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.5 12.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 19.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.5 5.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 2.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.5 22.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.5 3.4 GO:0042608 T cell receptor binding(GO:0042608)
0.5 1.0 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.5 3.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.5 3.6 GO:0046527 glucosyltransferase activity(GO:0046527)
0.4 1.3 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.4 3.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.4 2.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.4 2.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.4 2.0 GO:1990715 mRNA CDS binding(GO:1990715)
0.4 2.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.4 7.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.4 7.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.4 13.9 GO:0019842 vitamin binding(GO:0019842)
0.4 1.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.4 7.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.4 4.0 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.4 1.1 GO:0017042 glycosylceramidase activity(GO:0017042)
0.3 2.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 4.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.3 8.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.3 6.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 4.9 GO:0008199 ferric iron binding(GO:0008199)
0.3 4.9 GO:0050661 NADP binding(GO:0050661)
0.3 17.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.3 12.9 GO:0048029 monosaccharide binding(GO:0048029)
0.3 5.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.3 3.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 2.0 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.3 2.6 GO:0008494 translation activator activity(GO:0008494)
0.3 2.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.3 2.8 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 4.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.3 2.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 5.7 GO:0008301 DNA binding, bending(GO:0008301)
0.3 2.4 GO:0001618 virus receptor activity(GO:0001618)
0.3 0.8 GO:0071209 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.3 2.1 GO:0008097 5S rRNA binding(GO:0008097)
0.3 2.0 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 1.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 2.7 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.2 2.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 0.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 0.4 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 1.7 GO:0045545 syndecan binding(GO:0045545)
0.2 3.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.2 2.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 4.9 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 16.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 1.6 GO:0070403 NAD+ binding(GO:0070403)
0.2 1.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.2 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.2 6.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 4.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.2 0.9 GO:0050700 CARD domain binding(GO:0050700)
0.2 6.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 0.7 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 2.2 GO:0035497 cAMP response element binding(GO:0035497)
0.2 4.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 1.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 15.6 GO:0004540 ribonuclease activity(GO:0004540)
0.1 0.7 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.3 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.1 11.9 GO:0008083 growth factor activity(GO:0008083)
0.1 2.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 9.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 2.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.2 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 3.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 4.3 GO:0051213 dioxygenase activity(GO:0051213)
0.1 4.9 GO:0005506 iron ion binding(GO:0005506)
0.1 4.3 GO:0019843 rRNA binding(GO:0019843)
0.1 0.4 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 3.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 1.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 1.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 16.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.2 GO:0008254 3'-nucleotidase activity(GO:0008254)
0.1 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.6 GO:0043531 ADP binding(GO:0043531)
0.1 1.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 1.7 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 0.8 GO:0043422 protein kinase B binding(GO:0043422)
0.1 2.5 GO:0016835 carbon-oxygen lyase activity(GO:0016835)
0.1 1.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.8 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1 1.2 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 8.9 GO:0008168 methyltransferase activity(GO:0008168)
0.1 0.7 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 1.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.5 GO:0000049 tRNA binding(GO:0000049)
0.1 0.5 GO:0019808 polyamine binding(GO:0019808)
0.1 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0050145 uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 5.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.3 GO:0035375 zymogen binding(GO:0035375)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0030626 U12 snRNA binding(GO:0030626)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 136.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
3.6 195.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
2.7 34.8 ST STAT3 PATHWAY STAT3 Pathway
2.3 13.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
1.7 407.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
1.6 41.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
1.6 83.8 PID BMP PATHWAY BMP receptor signaling
1.2 26.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
1.2 52.5 PID IL6 7 PATHWAY IL6-mediated signaling events
1.1 41.3 PID IL1 PATHWAY IL1-mediated signaling events
1.1 30.3 PID IGF1 PATHWAY IGF1 pathway
1.1 26.4 PID ALK1 PATHWAY ALK1 signaling events
1.0 34.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.9 9.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.7 22.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.6 17.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.6 1.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.6 9.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.6 3.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.6 85.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.5 37.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.5 9.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.5 16.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.5 3.8 ST GAQ PATHWAY G alpha q Pathway
0.5 1.4 PID IL5 PATHWAY IL5-mediated signaling events
0.5 11.4 PID IL23 PATHWAY IL23-mediated signaling events
0.4 20.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.4 16.1 PID FGF PATHWAY FGF signaling pathway
0.4 16.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.3 11.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 3.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 2.3 ST ADRENERGIC Adrenergic Pathway
0.2 11.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 10.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 6.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 3.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 3.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 9.0 PID P73PATHWAY p73 transcription factor network
0.1 4.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 3.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 0.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 2.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 3.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 2.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 3.9 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 5.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.2 PID BCR 5PATHWAY BCR signaling pathway
0.1 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
14.9 283.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
10.5 115.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
10.4 125.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
10.3 113.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
7.4 103.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
7.4 96.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
7.2 150.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
6.7 66.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
5.4 144.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
4.7 47.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
4.0 35.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
2.9 84.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
2.4 41.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
2.4 38.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
2.1 59.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
2.0 24.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.9 3.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.9 32.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
1.8 25.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.7 26.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.7 22.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
1.6 12.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
1.5 19.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
1.4 15.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.4 32.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.3 13.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.3 21.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
1.3 109.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
1.3 193.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
1.3 12.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.2 4.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.2 7.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
1.1 9.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
1.0 13.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
1.0 12.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.0 13.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
1.0 12.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.9 9.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.9 13.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.8 35.3 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.8 12.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.8 22.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.8 36.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.8 21.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.7 3.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.7 44.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.7 30.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.6 5.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.6 40.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.6 9.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.6 6.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.5 5.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.5 4.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 15.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.4 3.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 10.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 2.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 8.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.4 18.5 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.4 6.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.4 2.8 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.3 5.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 2.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 3.9 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.3 4.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.3 3.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.3 13.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.3 3.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 2.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.3 6.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.3 2.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 4.8 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 28.9 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.2 5.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 14.1 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.2 5.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 5.6 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.2 14.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.4 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 0.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 0.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 2.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 3.3 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 1.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis