ISMARA results: Cdx2

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Cdx2

Z-value: 0.26

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Transcription factors associated with Cdx2

Gene Symbol	Gene ID	Gene Info
Cdx2 NCBI RGD Ensembl	ENSRNOG00000032759	caudal type homeo box 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Cdx2	rn6_v1_chr12_+_9464026_9464026	-0.10	8.5e-02	Click!

Activity profile of Cdx2 motif

Sorted Z-values of Cdx2 motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_+_201620642 Show fit	16.91	ENSRNOT00000093674	Dmbt1 NCBI RGD Ensembl Show fit	deleted in malignant brain tumors 1
chr4_+_99063181 Show fit	13.15	ENSRNOT00000008840	Fabp1 NCBI RGD Ensembl Show fit	fatty acid binding protein 1
chr10_+_53778662 Show fit	8.48	ENSRNOT00000045718	Myh2 NCBI RGD Ensembl Show fit	myosin heavy chain 2
chrX_+_120624518 Show fit	2.73	ENSRNOT00000007967	Slc6a14 NCBI RGD Ensembl Show fit	solute carrier family 6 member 14
chr19_-_11057254 Show fit	2.55	ENSRNOT00000025559	Herpud1 NCBI RGD Ensembl Show fit	homocysteine inducible ER protein with ubiquitin like domain 1
chr14_+_23405717 Show fit	1.68	ENSRNOT00000029805	Tmprss11c NCBI RGD Ensembl Show fit	transmembrane protease, serine 11C
chr1_+_103145939 Show fit	1.59	ENSRNOT00000040529	AABR07003273.1 NCBI RGD Ensembl Show fit
chr11_+_85618714 Show fit	0.75	ENSRNOT00000074614	AC109901.1 NCBI RGD Ensembl Show fit
chr10_-_87351030 Show fit	0.50	ENSRNOT00000034889 ENSRNOT00000091152	Krt20 NCBI RGD Ensembl Show fit	keratin 20
chr2_-_43067956 Show fit	0.26	ENSRNOT00000090616	Gpbp1 NCBI RGD Ensembl Show fit	GC-rich promoter binding protein 1

Showing 1 to 10 of 11 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Cdx2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.8	16.9	GO:0001833	inner cell mass cell proliferation(GO:0001833)
4.4	13.2	GO:0051977	lysophospholipid transport(GO:0051977)
0.7	8.5	GO:0001778	plasma membrane repair(GO:0001778)
0.0	2.7	GO:0006836	neurotransmitter transport(GO:0006836)
0.5	2.5	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.2	1.7	GO:0097264	self proteolysis(GO:0097264)
0.0	0.5	GO:0045109	intermediate filament organization(GO:0045109)

Showing 1 to 7 of 7 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.9	16.9	GO:0042589	zymogen granule membrane(GO:0042589)
1.3	13.2	GO:0045179	apical cortex(GO:0045179)
0.9	8.5	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	2.7	GO:0031526	brush border membrane(GO:0031526)
0.8	2.5	GO:1990037	Lewy body core(GO:1990037)

Showing 1 to 5 of 5 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.4	16.9	GO:0035375	zymogen binding(GO:0035375)
2.2	13.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	8.5	GO:0003779	actin binding(GO:0003779)
0.1	2.7	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	2.5	GO:0044325	ion channel binding(GO:0044325)
0.0	0.2	GO:0033038	bitter taste receptor activity(GO:0033038)

Showing 1 to 6 of 6 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	16.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	8.5	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events

Showing 1 to 2 of 2 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	13.2	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	2.7	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	2.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4

Showing 1 to 3 of 3 entries

Results for Cdx2

Z-value: 0.26

Motif logo

Transcription factors associated with Cdx2

Activity-expression correlation:

Activity profile of Cdx2 motif

Sorted Z-values of Cdx2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Cdx2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: