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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Cdc5l

Z-value: 0.24

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Transcription factors associated with Cdc5l

Gene Symbol Gene ID Gene Info
ENSRNOG00000019975 cell division cycle 5-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cdc5lrn6_v1_chr9_+_17949764_179497640.254.8e-06Click!

Activity profile of Cdc5l motif

Sorted Z-values of Cdc5l motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_52849907 5.26 ENSRNOT00000041096
sodium voltage-gated channel alpha subunit 7
chr9_-_32019205 4.61 ENSRNOT00000016194
adhesion G protein-coupled receptor B3
chr6_-_71199110 4.57 ENSRNOT00000081883
protein kinase D1
chr3_+_97723901 3.64 ENSRNOT00000080416
metallophosphoesterase domain containing 2
chr4_+_120672152 3.04 ENSRNOT00000077231
monoglyceride lipase
chr11_+_52828116 2.73 ENSRNOT00000035340
coiled-coil domain containing 54
chr7_-_144837583 2.43 ENSRNOT00000055289
chromobox 5
chr5_-_72287669 1.89 ENSRNOT00000022255
Kruppel like factor 4
chr1_+_15642153 1.56 ENSRNOT00000079845
microtubule-associated protein 7
chr7_-_144837395 1.53 ENSRNOT00000089024
chromobox 5
chr3_-_67787990 1.38 ENSRNOT00000064851
NCK-associated protein 1
chrX_+_78769419 1.35 ENSRNOT00000003190
T-box 22
chr12_+_22835019 1.25 ENSRNOT00000059530
collagen type XXVI alpha 1 chain
chrX_-_82699487 1.21 ENSRNOT00000081625
ribosomal protein S6 kinase A6
chr3_+_69549673 1.09 ENSRNOT00000043974
zinc finger protein 804A
chr20_-_45399694 1.04 ENSRNOT00000000715
adenosylmethionine decarboxylase 1
chr10_-_66020682 0.88 ENSRNOT00000011019
family with sequence similarity 58, member B
chr2_-_22096949 0.87 ENSRNOT00000089325
zinc finger FYVE-type containing 16
chr2_-_189395746 0.73 ENSRNOT00000089042
ubiquitin associated protein 2-like
chr13_+_98615287 0.65 ENSRNOT00000004032
inositol-trisphosphate 3-kinase B
chr15_+_28894627 0.63 ENSRNOT00000017795
olfactory receptor 1643
chr4_-_84127331 0.53 ENSRNOT00000085812
carboxypeptidase, vitellogenic-like
chr8_+_76426335 0.53 ENSRNOT00000085496
general transcription factor2A subunit 2
chr2_+_251534535 0.45 ENSRNOT00000080311

chr12_-_43576754 0.23 ENSRNOT00000042331
ENSRNOT00000081780
mediator complex subunit 13-like
chr2_+_184230459 0.09 ENSRNOT00000074187

Network of associatons between targets according to the STRING database.

First level regulatory network of Cdc5l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.6 GO:0061743 motor learning(GO:0061743)
0.8 4.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.8 3.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.6 1.9 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.3 1.4 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.2 1.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.7 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 1.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 5.3 GO:0055078 sodium ion homeostasis(GO:0055078)
0.1 1.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.9 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 GO:0043083 synaptic cleft(GO:0043083)
0.3 5.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 4.0 GO:0010369 chromocenter(GO:0010369)
0.2 4.6 GO:0000421 autophagosome membrane(GO:0000421)
0.2 1.4 GO:0031209 SCAR complex(GO:0031209)
0.2 3.0 GO:0043196 varicosity(GO:0043196)
0.1 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 3.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 4.6 GO:0004697 protein kinase C activity(GO:0004697)
0.2 5.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.0 GO:0019808 polyamine binding(GO:0019808)
0.1 0.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 4.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 4.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103) TBP-class protein binding(GO:0017025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 PID IGF1 PATHWAY IGF1 pathway
0.1 0.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 4.0 PID AURORA B PATHWAY Aurora B signaling
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 5.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 4.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 4.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening