ISMARA results: Bptf

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Bptf

Z-value: 1.28

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Transcription factors associated with Bptf

Gene Symbol	Gene ID	Gene Info
Bptf NCBI RGD Ensembl	ENSRNOG00000047296	bromodomain PHD finger transcription factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Bptf	rn6_v1_chr10_-_95349789_95349789	0.74	4.0e-56	Click!

Activity profile of Bptf motif

Sorted Z-values of Bptf motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_+_236625357 Show fit	34.54	ENSRNOT00000081248	Papss1 NCBI RGD Ensembl Show fit	3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr8_-_43336304 Show fit	30.90	ENSRNOT00000036054	RGD1311744 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 5830475I06
chr1_-_16687817 Show fit	25.65	ENSRNOT00000091376 ENSRNOT00000081620	Myb NCBI RGD Ensembl Show fit	MYB proto-oncogene, transcription factor
chr6_-_146195819 Show fit	22.00	ENSRNOT00000007625	Sp4 NCBI RGD Ensembl Show fit	Sp4 transcription factor
chr8_-_120446455 Show fit	20.16	ENSRNOT00000085161 ENSRNOT00000042854 ENSRNOT00000037199	Arpp21 NCBI RGD Ensembl Show fit	cAMP regulated phosphoprotein 21
chr7_+_58814805 Show fit	18.38	ENSRNOT00000005909	Tspan8 NCBI RGD Ensembl Show fit	tetraspanin 8
chr19_-_40925660 Show fit	18.27	ENSRNOT00000023645	Mtss1l NCBI RGD Ensembl Show fit	MTSS1L, I-BAR domain containing
chr17_+_43633675 Show fit	16.89	ENSRNOT00000072119	LOC102549173 NCBI RGD Ensembl Show fit	histone H3.2-like
chr7_-_15852930 Show fit	16.81	ENSRNOT00000009270	LOC691422 NCBI RGD Ensembl Show fit	similar to zinc finger protein 101
chr2_+_93792601 Show fit	16.69	ENSRNOT00000014701 ENSRNOT00000077311	Fabp4 NCBI RGD Ensembl Show fit	fatty acid binding protein 4

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Bptf

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
4.9	34.5	GO:0000103	sulfate assimilation(GO:0000103)
2.7	32.3	GO:0060923	cardiac muscle cell fate commitment(GO:0060923)
0.7	25.9	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
8.6	25.7	GO:2000845	positive regulation of testosterone secretion(GO:2000845)
0.4	20.7	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
1.1	20.6	GO:0050872	white fat cell differentiation(GO:0050872)
0.3	20.5	GO:0006334	nucleosome assembly(GO:0006334)
4.1	20.4	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
1.2	20.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.7	19.7	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336)

Showing 1 to 10 of 516 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	41.6	GO:0016607	nuclear speck(GO:0016607)
0.0	41.3	GO:0005654	nucleoplasm(GO:0005654)
0.5	37.2	GO:0044815	DNA packaging complex(GO:0044815)
0.0	35.1	GO:0005634	nucleus(GO:0005634)
0.2	26.2	GO:0000775	chromosome, centromeric region(GO:0000775)
0.8	23.6	GO:0000788	nuclear nucleosome(GO:0000788)
0.3	23.5	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	22.8	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
3.6	21.5	GO:0071547	piP-body(GO:0071547)
2.5	20.4	GO:0097443	sorting endosome(GO:0097443)

Showing 1 to 10 of 259 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	236.3	GO:0003676	nucleic acid binding(GO:0003676)
0.3	58.7	GO:0042393	histone binding(GO:0042393)
0.1	36.6	GO:0005096	GTPase activator activity(GO:0005096)
0.5	35.7	GO:0004004	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
11.5	34.5	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2	31.0	GO:0003713	transcription coactivator activity(GO:0003713)
0.6	26.8	GO:0048365	Rac GTPase binding(GO:0048365)
0.5	25.8	GO:0004386	helicase activity(GO:0004386)
5.1	25.7	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.1	25.3	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)

Showing 1 to 10 of 328 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.9	49.2	PID FANCONI PATHWAY	Fanconi anemia pathway
0.7	35.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.7	33.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.7	32.2	PID AURORA B PATHWAY	Aurora B signaling
0.7	23.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.4	17.9	PID INSULIN PATHWAY	Insulin Pathway
0.3	15.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.3	15.5	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.4	15.1	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.2	14.9	WNT SIGNALING	Genes related to Wnt-mediated signal transduction

Showing 1 to 10 of 76 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	37.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.3	35.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
2.7	34.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	32.1	REACTOME TRANSLATION	Genes involved in Translation
0.5	25.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.3	24.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.8	22.0	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.3	20.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	17.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
1.1	16.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis

Showing 1 to 10 of 122 entries

Results for Bptf

Z-value: 1.28

Motif logo

Transcription factors associated with Bptf

Activity-expression correlation:

Activity profile of Bptf motif

Sorted Z-values of Bptf motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Bptf

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: