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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Batf

Z-value: 0.66

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Transcription factors associated with Batf

Gene Symbol Gene ID Gene Info
Batf
ENSRNOG00000008588 basic leucine zipper ATF-like transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Batfrn6_v1_chr6_+_109562587_1095625870.395.6e-13Click!

Activity profile of Batf motif

Sorted Z-values of Batf motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_227207584 26.34 ENSRNOT00000065361
ENSRNOT00000080215
Myoz2
myozenin 2
chr4_-_164051812 18.25 ENSRNOT00000085719
AABR07062183.1

chr19_+_37235001 16.91 ENSRNOT00000020908
Nol3
nucleolar protein 3
chr4_-_163810403 16.34 ENSRNOT00000079704
AABR07062170.1

chr1_+_199555722 14.23 ENSRNOT00000054983
Itgax
integrin subunit alpha X
chr15_-_28081465 13.19 ENSRNOT00000033739
Rnase6
ribonuclease, RNase A family, 6
chrX_+_104734082 12.35 ENSRNOT00000005020
Srpx2
sushi-repeat-containing protein, X-linked 2
chr8_+_5606592 12.19 ENSRNOT00000011727
Mmp12
matrix metallopeptidase 12
chr5_+_64476317 11.92 ENSRNOT00000017217
LOC108348074
collagen alpha-1(XV) chain-like
chr14_+_34727623 11.52 ENSRNOT00000071405
ENSRNOT00000090183
Kdr
kinase insert domain receptor
chr16_-_9430743 11.25 ENSRNOT00000043811
Wdfy4
WDFY family member 4
chr10_+_69423086 10.97 ENSRNOT00000000256
Ccl7
C-C motif chemokine ligand 7
chr3_+_19274273 10.85 ENSRNOT00000040102
AABR07051684.1

chr8_-_49038169 10.56 ENSRNOT00000047303
Phldb1
pleckstrin homology-like domain, family B, member 1
chr8_+_133210473 10.21 ENSRNOT00000082774
Ccr5
chemokine (C-C motif) receptor 5
chr4_+_98481520 9.86 ENSRNOT00000078381
ENSRNOT00000048493
AABR07060886.1

chr18_+_56414488 9.67 ENSRNOT00000088988
Csf1r
colony stimulating factor 1 receptor
chr14_-_81053905 9.07 ENSRNOT00000045068
ENSRNOT00000040215
Rgs12
regulator of G-protein signaling 12
chr5_+_154265097 9.00 ENSRNOT00000012342
Cnr2
cannabinoid receptor 2
chr10_+_83655460 8.91 ENSRNOT00000008011
Gngt2
G protein subunit gamma transducin 2
chr4_-_41212072 8.87 ENSRNOT00000085596
Ppp1r3a
protein phosphatase 1, regulatory subunit 3A
chr4_-_17440506 8.76 ENSRNOT00000080931
Sema3e
semaphorin 3E
chr3_-_16441030 8.29 ENSRNOT00000047784
AABR07051532.1

chr2_+_153803349 8.12 ENSRNOT00000088565
Mme
membrane metallo-endopeptidase
chrX_-_31851715 7.86 ENSRNOT00000068601
Vegfd
vascular endothelial growth factor D
chrX_-_10031167 7.47 ENSRNOT00000060988
Gpr34
G protein-coupled receptor 34
chr14_-_28856214 7.27 ENSRNOT00000044659
Adgrl3
adhesion G protein-coupled receptor L3
chr7_+_145068286 6.93 ENSRNOT00000088956
ENSRNOT00000065753
Nckap1l
NCK associated protein 1 like
chr3_+_16571602 6.65 ENSRNOT00000048351
LOC100361705
rCG64259-like
chrX_+_43625169 5.64 ENSRNOT00000086311
Sat1
spermidine/spermine N1-acetyl transferase 1
chr3_-_48535909 5.39 ENSRNOT00000008148
Fap
fibroblast activation protein, alpha
chr17_-_22143324 5.30 ENSRNOT00000019361
Edn1
endothelin 1
chr4_-_155690869 5.28 ENSRNOT00000012216
C3ar1
complement C3a receptor 1
chr4_-_103761881 5.28 ENSRNOT00000084103
AABR07061087.1

chr2_-_32518643 4.85 ENSRNOT00000061032
Mast4
microtubule associated serine/threonine kinase family member 4
chr2_+_118547190 4.71 ENSRNOT00000083676
ENSRNOT00000090301
ENSRNOT00000013410
Kcnmb2
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr4_+_3043231 4.59 ENSRNOT00000013732
Il6
interleukin 6
chr13_-_69984785 4.54 ENSRNOT00000083995
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr20_+_18833481 3.86 ENSRNOT00000080846
Bicc1
BicC family RNA binding protein 1
chr18_+_15467870 3.81 ENSRNOT00000091696
B4galt6
beta-1,4-galactosyltransferase 6
chr6_+_136358057 3.62 ENSRNOT00000092741
Klc1
kinesin light chain 1
chr10_-_37455022 3.55 ENSRNOT00000016742
LOC103694902
ubiquitin-conjugating enzyme E2 B
chr3_-_29984201 3.21 ENSRNOT00000006350
Zeb2
zinc finger E-box binding homeobox 2
chr10_-_83655182 3.18 ENSRNOT00000007897
Abi3
ABI family, member 3
chr5_-_163231494 3.16 ENSRNOT00000085929
ENSRNOT00000022968
Tnfrsf8
TNF receptor superfamily member 8
chr2_-_177950517 3.09 ENSRNOT00000012792
Rapgef2
Rap guanine nucleotide exchange factor 2
chr14_-_85484275 2.98 ENSRNOT00000083770
Kremen1
kringle containing transmembrane protein 1
chr9_+_117737611 2.97 ENSRNOT00000022396
Zfp161
zinc finger protein 161
chr4_-_138830117 2.97 ENSRNOT00000008403
Il5ra
interleukin 5 receptor subunit alpha
chr2_-_123972356 2.86 ENSRNOT00000023348
Il21
interleukin 21
chr2_+_144861455 2.71 ENSRNOT00000093284
ENSRNOT00000019748
ENSRNOT00000072110
Dclk1
doublecortin-like kinase 1
chr2_+_2605996 2.70 ENSRNOT00000016372
Glrx
glutaredoxin
chr18_+_3861539 2.70 ENSRNOT00000015363
Lama3
laminin subunit alpha 3
chr1_+_220428481 2.57 ENSRNOT00000027335
LOC108348044
ras and Rab interactor 1
chr1_+_220335254 2.53 ENSRNOT00000072261
Rin1
Ras and Rab interactor 1
chr15_-_41508952 2.51 ENSRNOT00000064503
AABR07018124.1

chr4_-_22307453 2.32 ENSRNOT00000047126
Abcb1a
ATP binding cassette subfamily B member 1A
chr3_-_161812243 2.26 ENSRNOT00000025238
ENSRNOT00000087646
Slc35c2
solute carrier family 35 member C2
chrX_-_111179152 2.23 ENSRNOT00000089115
Morc4
MORC family CW-type zinc finger 4
chr13_-_90977734 2.17 ENSRNOT00000011869
Slamf8
SLAM family member 8
chr3_+_2642531 2.10 ENSRNOT00000081798
Fut7
fucosyltransferase 7
chr1_-_66645214 1.93 ENSRNOT00000084168
LOC100365062
eukaryotic translation initiation factor 3, subunit 6 48kDa-like
chr5_-_77031120 1.92 ENSRNOT00000022987
Inip
INTS3 and NABP interacting protein
chr1_-_66639205 1.92 ENSRNOT00000082190
LOC100909481
eukaryotic translation initiation factor 3 subunit E-like
chr1_+_46230557 1.70 ENSRNOT00000092849
Arid1b
AT-rich interaction domain 1B
chr16_-_19637609 1.65 ENSRNOT00000021742
Zfp709
zinc finger protein 709
chr14_-_24080470 1.64 ENSRNOT00000002745
Tmprss11f
transmembrane protease, serine 11f
chr10_-_85084850 1.59 ENSRNOT00000012462
Tbkbp1
TBK1 binding protein 1
chr6_+_135610743 1.53 ENSRNOT00000010906
Traf3
Tnf receptor-associated factor 3
chr8_+_85951191 1.48 ENSRNOT00000037665
Cd109
CD109 molecule
chr18_+_36596585 1.41 ENSRNOT00000036613
Rbm27
RNA binding motif protein 27
chr3_+_102703487 1.38 ENSRNOT00000089603
AC121203.2

chr3_-_78640261 1.26 ENSRNOT00000048787
Olr717
olfactory receptor 717
chr2_-_251970768 1.22 ENSRNOT00000020141
Wdr63
WD repeat domain 63
chr3_-_64095120 1.16 ENSRNOT00000016837
Sestd1
SEC14 and spectrin domain containing 1
chr12_-_21746236 1.16 ENSRNOT00000001869
LOC102550456
TSC22 domain family protein 4-like
chr5_+_169181418 1.14 ENSRNOT00000004508
Klhl21
kelch-like family member 21
chr2_+_149843282 1.01 ENSRNOT00000074805
RGD1561998
similar to hypothetical protein C130079G13
chr8_+_19886382 0.95 ENSRNOT00000034254
Zfp317
zinc finger protein 317
chr18_+_86116044 0.95 ENSRNOT00000058160
ENSRNOT00000076159
Rttn
rotatin
chr1_+_72210037 0.90 ENSRNOT00000058999
Vom1r37
vomeronasal 1 receptor 37
chrM_+_7919 0.86 ENSRNOT00000046108
Mt-atp6
mitochondrially encoded ATP synthase 6
chr2_-_183210799 0.79 ENSRNOT00000085382
Trim2
tripartite motif-containing 2
chr4_-_72023952 0.79 ENSRNOT00000059395
Fam115e
family with sequence similarity 115, member E
chr7_+_59200918 0.70 ENSRNOT00000085073
Ptprr
protein tyrosine phosphatase, receptor type, R
chr3_-_20883265 0.68 ENSRNOT00000052047
Olr414
olfactory receptor 414
chr1_-_98486976 0.66 ENSRNOT00000024083
Etfb
electron transfer flavoprotein beta subunit
chr8_+_114866768 0.60 ENSRNOT00000076731
Wdr82
WD repeat domain 82
chr2_+_243425007 0.43 ENSRNOT00000082894
Trmt10a
tRNA methyltransferase 10A
chr3_-_78555530 0.29 ENSRNOT00000089672
Olr711
olfactory receptor 711
chr1_+_199323628 0.25 ENSRNOT00000036187
Zfp646
zinc finger protein 646
chr3_+_75465399 0.09 ENSRNOT00000057479
Olr562
olfactory receptor 562
chr2_+_46210713 0.09 ENSRNOT00000074742
LOC100910111
olfactory receptor 147-like
chr3_-_78409263 0.03 ENSRNOT00000041001
Olr704
olfactory receptor 704
chrX_+_908044 0.01 ENSRNOT00000072087
Zfp300
zinc finger protein 300

Network of associatons between targets according to the STRING database.

First level regulatory network of Batf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.9 GO:0014736 negative regulation of muscle atrophy(GO:0014736)
3.4 10.2 GO:2000464 positive regulation of astrocyte chemotaxis(GO:2000464)
3.0 12.2 GO:0072641 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
2.3 6.9 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
2.0 8.1 GO:0071492 cellular response to UV-A(GO:0071492)
1.9 9.7 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
1.9 11.5 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
1.8 11.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.8 5.4 GO:0097325 melanocyte proliferation(GO:0097325)
1.8 5.3 GO:0031583 phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
1.8 5.3 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
1.6 7.9 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
1.5 12.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
1.5 4.6 GO:2000660 negative regulation of chemokine biosynthetic process(GO:0045079) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.5 9.1 GO:0023021 termination of signal transduction(GO:0023021)
1.4 5.6 GO:0032919 spermine acetylation(GO:0032919)
1.1 3.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
1.1 3.2 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
1.0 9.0 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.9 2.7 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.8 10.6 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.8 3.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.8 2.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.7 3.6 GO:0035617 stress granule disassembly(GO:0035617)
0.6 2.3 GO:1905235 carbohydrate export(GO:0033231) cellular response to mycotoxin(GO:0036146) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
0.5 2.2 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of neutrophil migration(GO:1902623)
0.5 2.9 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.4 1.7 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.4 26.3 GO:0030239 myofibril assembly(GO:0030239)
0.4 7.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.3 4.7 GO:0005513 detection of calcium ion(GO:0005513)
0.3 3.8 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.3 8.8 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.2 1.5 GO:0072675 osteoclast fusion(GO:0072675)
0.2 14.2 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.2 2.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 3.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 1.2 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2 2.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) fucosylation(GO:0036065)
0.2 0.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.2 1.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 2.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 3.0 GO:0032674 regulation of interleukin-5 production(GO:0032674)
0.1 1.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 13.2 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.1 2.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 6.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 3.0 GO:0003170 heart valve development(GO:0003170)
0.0 0.6 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 1.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.7 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 1.0 GO:0034605 cellular response to heat(GO:0034605)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.5 4.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.4 11.5 GO:0097443 sorting endosome(GO:0097443)
0.9 5.3 GO:0033093 Weibel-Palade body(GO:0033093) rough endoplasmic reticulum lumen(GO:0048237)
0.8 6.9 GO:0031209 SCAR complex(GO:0031209)
0.7 10.6 GO:0045180 basal cortex(GO:0045180)
0.5 2.2 GO:0071438 invadopodium membrane(GO:0071438)
0.5 3.8 GO:0033290 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290)
0.5 1.9 GO:0070876 SOSS complex(GO:0070876)
0.4 2.7 GO:0005608 laminin-3 complex(GO:0005608)
0.4 14.2 GO:0008305 integrin complex(GO:0008305)
0.3 3.6 GO:0035253 ciliary rootlet(GO:0035253)
0.3 9.1 GO:0097440 apical dendrite(GO:0097440)
0.2 16.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.2 8.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 26.3 GO:0030018 Z disc(GO:0030018)
0.2 1.1 GO:0005827 polar microtubule(GO:0005827)
0.1 1.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 7.7 GO:0005581 collagen trimer(GO:0005581)
0.1 9.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 5.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.0 GO:0016235 aggresome(GO:0016235)
0.1 0.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 4.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 8.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 14.4 GO:0060076 excitatory synapse(GO:0060076)
0.0 2.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.3 GO:0031526 brush border membrane(GO:0031526)
0.0 1.2 GO:0034704 calcium channel complex(GO:0034704)
0.0 8.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.1 GO:0030139 endocytic vesicle(GO:0030139)
0.0 5.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 19.5 GO:0005615 extracellular space(GO:0005615)
0.0 2.3 GO:0030027 lamellipodium(GO:0030027)
0.0 6.3 GO:0030424 axon(GO:0030424)
0.0 2.5 GO:0030425 dendrite(GO:0030425)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 26.3 GO:0051373 FATZ binding(GO:0051373)
4.2 16.9 GO:0035877 death effector domain binding(GO:0035877)
3.5 21.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
2.3 9.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
1.9 5.6 GO:0019809 spermidine binding(GO:0019809)
1.8 5.3 GO:0031708 endothelin B receptor binding(GO:0031708)
1.4 11.5 GO:0038085 vascular endothelial growth factor-activated receptor activity(GO:0005021) vascular endothelial growth factor binding(GO:0038085)
1.0 3.8 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.9 4.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.9 7.9 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.7 8.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.7 4.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.6 2.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.5 5.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.5 3.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.5 5.3 GO:0004875 complement receptor activity(GO:0004875)
0.5 2.3 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.4 2.7 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.4 2.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 3.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 9.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 9.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.2 4.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 16.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 13.2 GO:0004540 ribonuclease activity(GO:0004540)
0.1 3.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 13.8 GO:0019838 growth factor binding(GO:0019838)
0.1 0.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 6.1 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 1.5 GO:0031996 thioesterase binding(GO:0031996)
0.1 3.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 3.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 7.7 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 4.9 GO:0000287 magnesium ion binding(GO:0000287)
0.0 4.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 5.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 11.9 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.7 GO:0009055 electron carrier activity(GO:0009055)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 11.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.5 14.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.4 3.0 PID IL5 PATHWAY IL5-mediated signaling events
0.4 4.6 ST STAT3 PATHWAY STAT3 Pathway
0.3 8.9 PID CONE PATHWAY Visual signal transduction: Cones
0.3 8.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 8.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 9.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.2 5.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 3.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 2.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 10.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 3.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 3.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 5.3 PID ENDOTHELIN PATHWAY Endothelins
0.1 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 8.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 8.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 8.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 10.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.0 11.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.5 8.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 8.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.4 4.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 5.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 11.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 3.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 4.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 14.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 3.6 REACTOME KINESINS Genes involved in Kinesins
0.1 1.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 3.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 13.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 5.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport