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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Barhl1

Z-value: 0.55

Motif logo

Transcription factors associated with Barhl1

Gene Symbol Gene ID Gene Info
ENSRNOG00000013209 BarH-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Barhl1rn6_v1_chr3_-_7498555_7498555-0.054.2e-01Click!

Activity profile of Barhl1 motif

Sorted Z-values of Barhl1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_5606592 16.87 ENSRNOT00000011727
matrix metallopeptidase 12
chr1_+_279896973 14.40 ENSRNOT00000068119
pancreatic lipase related protein 2
chr6_-_138852571 11.67 ENSRNOT00000081803

chr6_-_139747737 11.66 ENSRNOT00000090626

chrX_-_118459355 10.82 ENSRNOT00000084465
interleukin 13 receptor subunit alpha 2
chr4_-_164406146 10.53 ENSRNOT00000090110
killer cell lectin-like receptor subfamily A, member 22
chr6_-_139041812 10.30 ENSRNOT00000074510

chr6_+_139523337 9.53 ENSRNOT00000090711

chr11_-_69201380 9.48 ENSRNOT00000085618
myosin light chain kinase
chrX_+_14578264 9.18 ENSRNOT00000038994
cytochrome b-245 beta chain
chr2_-_157759819 8.95 ENSRNOT00000015763
ENSRNOT00000016016
cyclin-L1-like
chr14_+_59611434 8.35 ENSRNOT00000065366
cholecystokinin A receptor
chr4_-_70934295 7.77 ENSRNOT00000020616
transient receptor potential cation channel, subfamily V, member 6
chr3_+_16571602 7.13 ENSRNOT00000048351
rCG64259-like
chr3_+_94549180 6.90 ENSRNOT00000016318
cleavage stimulation factor subunit 3
chr4_-_165026414 6.80 ENSRNOT00000071421
killer cell lectin-like receptor, subfamily A, member 1
chr3_+_103753238 6.67 ENSRNOT00000007144
solute carrier family 12, member 6
chr2_+_185846232 6.45 ENSRNOT00000023418
LPS responsive beige-like anchor protein
chr3_-_112985318 6.32 ENSRNOT00000015556
erythrocyte membrane protein band 4.2
chr18_+_56431820 6.08 ENSRNOT00000079360
ENSRNOT00000049357
colony stimulating factor 1 receptor
chr2_-_49128501 5.76 ENSRNOT00000073847
poly (ADP-ribose) polymerase family, member 8
chr14_+_17210733 5.74 ENSRNOT00000003075
C-X-C motif chemokine ligand 10
chr13_+_47572219 5.43 ENSRNOT00000088449
ENSRNOT00000087664
ENSRNOT00000005853
polymeric immunoglobulin receptor
chr16_-_3765917 5.32 ENSRNOT00000088284
double homeobox B-like 1
chr1_-_73732118 4.88 ENSRNOT00000077964
leukocyte receptor cluster member 8
chr9_+_71915421 4.64 ENSRNOT00000020447
phosphoinositide kinase, FYVE-type zinc finger containing
chr3_+_114102875 4.38 ENSRNOT00000023209
tripartite motif-containing 69
chr1_-_37932084 4.34 ENSRNOT00000022527
zinc finger protein 728-like
chr15_+_31417147 4.32 ENSRNOT00000092182

chr16_+_22979444 4.15 ENSRNOT00000017822
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr10_+_90376933 4.15 ENSRNOT00000028557
granulin precursor
chr8_-_104155775 4.00 ENSRNOT00000042885
60S ribosomal protein L31-like
chr10_+_90377103 3.50 ENSRNOT00000040472
granulin precursor
chr7_+_130308532 3.39 ENSRNOT00000011941
myo-inositol oxygenase
chr4_+_57378069 3.38 ENSRNOT00000080173
ENSRNOT00000011851
nuclear respiratory factor 1
chr1_+_53220397 3.36 ENSRNOT00000089989

chr15_-_44673765 3.35 ENSRNOT00000048783

chr20_+_3992496 3.23 ENSRNOT00000082047
proteasome subunit beta 8
chr7_+_76092503 3.20 ENSRNOT00000079692
grainyhead-like transcription factor 2
chr5_+_144927759 3.20 ENSRNOT00000051387

chr3_+_5709236 3.12 ENSRNOT00000061201
ENSRNOT00000070887
dopamine beta-hydroxylase
chr15_+_30570483 2.93 ENSRNOT00000071740

chr3_+_11207542 2.92 ENSRNOT00000013546
proline-rich coiled-coil 2B
chr20_-_32296840 2.80 ENSRNOT00000080727
storkhead box 1
chr12_+_12859661 2.73 ENSRNOT00000001404
ubiquitin specific peptidase 42
chr11_-_45124423 2.67 ENSRNOT00000046383
filamin A interacting protein 1-like
chr3_-_59166356 2.66 ENSRNOT00000047713

chr7_+_144080614 2.56 ENSRNOT00000077687
poly(rC) binding protein 2
chr15_+_31010891 2.43 ENSRNOT00000088134

chr1_-_73226777 2.36 ENSRNOT00000025080
natural cytotoxicity triggering receptor 1
chr2_-_30340103 2.14 ENSRNOT00000024023
ENSRNOT00000067722
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr6_-_75670135 2.05 ENSRNOT00000007300
sorting nexin 6
chr6_-_50941248 1.85 ENSRNOT00000084533
dihydrouridine synthase 4-like
chr4_-_85174931 1.84 ENSRNOT00000014324
ENSRNOT00000088085
nucleotide-binding oligomerization domain containing 1
chr1_-_197801634 1.74 ENSRNOT00000090200
nuclear factor of activated T-cells 2 interacting protein
chr4_+_157864969 1.73 ENSRNOT00000048529
TNF receptor superfamily member 1A
chr10_+_10530365 1.66 ENSRNOT00000003843
eukaryotic elongation factor 2 lysine methyltransferase
chr18_+_4325875 1.65 ENSRNOT00000073771
impact RWD domain protein
chr1_+_205911552 1.54 ENSRNOT00000024751
fibronectin type 3 and ankyrin repeat domains 1
chr1_-_8038665 1.45 ENSRNOT00000046539
androgen-induced 1
chr19_-_25955371 1.43 ENSRNOT00000004042
ENSRNOT00000084123
RAD23 homolog A, nucleotide excision repair protein
chrX_+_123751089 1.41 ENSRNOT00000092384
NFKB activating protein
chr10_-_90127600 1.28 ENSRNOT00000028368
LSM12 homolog
chr3_+_154437571 1.24 ENSRNOT00000019331

chr2_-_170301348 1.16 ENSRNOT00000088131
sucrase-isomaltase
chr9_-_82477136 1.08 ENSRNOT00000026753
ENSRNOT00000089555
regulated endocrine-specific protein 18
chr11_+_45339366 0.97 ENSRNOT00000002241
transmembrane protein 30C
chr8_+_20132900 0.89 ENSRNOT00000045980

chr9_-_8899144 0.82 ENSRNOT00000051043

chr10_-_87136026 0.78 ENSRNOT00000014230
ENSRNOT00000083233
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr11_-_87403367 0.77 ENSRNOT00000057751
THAP domain containing 7
chr4_+_31333970 0.74 ENSRNOT00000064866
coiled-coil domain-containing protein 132-like
chr13_-_70299733 0.72 ENSRNOT00000044235
SMG7 nonsense mediated mRNA decay factor
chr1_-_54036068 0.69 ENSRNOT00000075019
similar to putative protein kinase
chr8_+_41336340 0.61 ENSRNOT00000072049
olfactory receptor 1225
chr9_+_66888393 0.60 ENSRNOT00000023536
calcium responsive transcription factor
chr5_+_36566783 0.58 ENSRNOT00000077650
F-box and leucine-rich repeat protein 4
chr4_-_66624912 0.53 ENSRNOT00000064891
homeodomain interacting protein kinase 2
chr10_+_63635219 0.52 ENSRNOT00000081813
ENSRNOT00000005016
pre-mRNA processing factor 8
chr9_+_98438439 0.43 ENSRNOT00000027220
selenocysteine lyase
chr12_-_37910439 0.41 ENSRNOT00000001433
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr20_-_46044738 0.32 ENSRNOT00000000343
FIG4 phosphoinositide 5-phosphatase
chr15_+_28695912 0.32 ENSRNOT00000081830
TOX high mobility group box family member 4
chr3_+_114900343 0.31 ENSRNOT00000068129
sulfide quinone reductase-like (yeast)
chr18_-_36579403 0.19 ENSRNOT00000025284
leucyl-tRNA synthetase
chr5_+_132005738 0.17 ENSRNOT00000041421
selection and upkeep of intraepithelial T cells 4
chr1_-_140835151 0.16 ENSRNOT00000032174
hyaluronan and proteoglycan link protein 3
chr1_-_172552099 0.09 ENSRNOT00000090373
olfactory receptor 257
chr2_+_198721724 0.01 ENSRNOT00000043535
ankyrin repeat domain 34A

Network of associatons between targets according to the STRING database.

First level regulatory network of Barhl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 16.9 GO:0072642 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
3.1 9.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
2.4 9.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
2.2 6.7 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
2.1 8.3 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
2.1 14.4 GO:0019374 galactolipid metabolic process(GO:0019374)
1.9 5.7 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
1.8 5.4 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.4 4.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
1.3 7.6 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
1.2 6.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
1.1 10.8 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
1.0 3.1 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.9 7.8 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.8 3.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.7 8.9 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.6 2.4 GO:0009597 detection of virus(GO:0009597)
0.5 1.6 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.5 5.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.4 2.8 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.3 2.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.3 6.3 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.3 1.8 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.3 2.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.3 2.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.2 1.8 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.2 5.0 GO:0032288 myelin assembly(GO:0032288)
0.2 3.4 GO:0006020 inositol metabolic process(GO:0006020)
0.1 3.4 GO:0051593 response to folic acid(GO:0051593)
0.1 1.7 GO:1903140 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.1 1.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.5 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.4 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 0.6 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 1.4 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 1.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.7 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 3.2 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 2.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.9 9.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.8 3.1 GO:0034774 secretory granule lumen(GO:0034774)
0.8 14.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.5 3.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 4.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 2.1 GO:0097422 tubular endosome(GO:0097422)
0.2 2.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.2 9.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 1.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 8.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 5.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 4.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.8 GO:0071564 npBAF complex(GO:0071564)
0.1 8.3 GO:0043195 terminal bouton(GO:0043195)
0.0 16.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.4 GO:0016234 inclusion body(GO:0016234)
0.0 6.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 8.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.6 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 6.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 7.8 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 4.4 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0005903 brush border(GO:0005903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.7 6.7 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
1.4 4.2 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
1.1 5.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.1 14.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
1.0 3.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
1.0 9.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174) superoxide-generating NADPH oxidase activity(GO:0016175)
0.6 6.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.6 4.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.5 2.1 GO:0001156 transcription factor activity, core RNA polymerase III binding(GO:0000995) TFIIIC-class transcription factor binding(GO:0001156)
0.5 2.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.5 5.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.4 1.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.3 1.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.3 1.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 3.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 1.8 GO:0050700 CARD domain binding(GO:0050700)
0.3 8.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3 2.1 GO:0034452 dynactin binding(GO:0034452)
0.2 1.7 GO:0031386 protein tag(GO:0031386)
0.2 16.9 GO:0005518 collagen binding(GO:0005518)
0.2 3.4 GO:0008199 ferric iron binding(GO:0008199)
0.2 7.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 3.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 10.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 6.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 1.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 8.3 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 0.4 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 17.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 7.4 GO:0005125 cytokine activity(GO:0005125)
0.0 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.7 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 2.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.7 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 1.6 GO:0043022 ribosome binding(GO:0043022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 10.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 16.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 13.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 9.5 PID AURORA B PATHWAY Aurora B signaling
0.2 5.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 9.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.4 9.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 6.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.3 14.4 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.3 9.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 3.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 1.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 4.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 5.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.8 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 2.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 3.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 8.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 6.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism