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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Atoh1_Bhlhe23

Z-value: 0.55

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Transcription factors associated with Atoh1_Bhlhe23

Gene Symbol Gene ID Gene Info
Atoh1
ENSRNOG00000006383 atonal bHLH transcription factor 1
Bhlhe23
ENSRNOG00000010312 basic helix-loop-helix family, member e23

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Atoh1rn6_v1_chr4_+_95498003_954980030.156.3e-03Click!
Bhlhe23rn6_v1_chr3_-_176282211_1762822110.009.8e-01Click!

Activity profile of Atoh1_Bhlhe23 motif

Sorted Z-values of Atoh1_Bhlhe23 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_40038336 30.93 ENSRNOT00000048804
Galnt13
polypeptide N-acetylgalactosaminyltransferase 13
chr8_-_63750531 22.87 ENSRNOT00000009496
Neo1
neogenin 1
chr8_+_69971778 21.28 ENSRNOT00000058007
ENSRNOT00000037941
ENSRNOT00000050649
Megf11
multiple EGF-like-domains 11
chr5_+_104362971 19.35 ENSRNOT00000058520
Adamtsl1
ADAMTS-like 1
chr5_+_58636083 19.00 ENSRNOT00000067281
Unc13b
unc-13 homolog B
chr11_-_88972176 18.18 ENSRNOT00000002498
Pkp2
plakophilin 2
chr16_+_2706428 16.59 ENSRNOT00000077117
Il17rd
interleukin 17 receptor D
chr3_-_38090526 16.47 ENSRNOT00000059430
Cacnb4
calcium voltage-gated channel auxiliary subunit beta 4
chr10_-_63952726 12.80 ENSRNOT00000090461
Doc2b
double C2 domain beta
chr16_-_32753278 11.80 ENSRNOT00000015759
Mfap3l
microfibrillar-associated protein 3-like
chr6_+_60566196 11.59 ENSRNOT00000006709
ENSRNOT00000075193
Dock4
dedicator of cytokinesis 4
chr11_+_72705129 11.25 ENSRNOT00000073330
Apod
apolipoprotein D
chr18_-_58423196 10.93 ENSRNOT00000025556
Piezo2
piezo-type mechanosensitive ion channel component 2
chr9_+_51298426 10.66 ENSRNOT00000065212
Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr5_-_12563429 10.04 ENSRNOT00000059625
St18
suppression of tumorigenicity 18
chr17_+_69468427 9.77 ENSRNOT00000058413
RGD1564865
similar to 20-alpha-hydroxysteroid dehydrogenase
chr4_-_31730386 8.32 ENSRNOT00000013817
Slc25a13
solute carrier family 25 member 13
chr5_+_98469047 7.43 ENSRNOT00000041374
Lurap1l
leucine rich adaptor protein 1-like
chr3_-_66417741 7.39 ENSRNOT00000007662
Neurod1
neuronal differentiation 1
chr15_+_43905099 7.24 ENSRNOT00000016568
Ebf2
early B-cell factor 2
chr2_-_100372252 7.16 ENSRNOT00000011890
Hnf4g
hepatocyte nuclear factor 4, gamma
chr4_+_122365093 6.76 ENSRNOT00000024011
Klf15
Kruppel-like factor 15
chr19_+_20147037 6.56 ENSRNOT00000020028
Zfp423
zinc finger protein 423
chr7_-_132343169 6.53 ENSRNOT00000021064
Abcd2
ATP binding cassette subfamily D member 2
chr6_+_34030620 6.26 ENSRNOT00000091651
Laptm4a
lysosomal protein transmembrane 4 alpha
chr11_+_9642365 6.15 ENSRNOT00000087080
ENSRNOT00000042384
Robo1
roundabout guidance receptor 1
chr4_-_82194927 5.75 ENSRNOT00000072302
LOC103692128
homeobox protein Hox-A9
chr11_-_87449940 5.72 ENSRNOT00000002560
Slc7a4
solute carrier family 7, member 4
chr17_+_87274944 5.71 ENSRNOT00000073718
Etl4
enhancer trap locus 4
chr4_-_173640684 5.65 ENSRNOT00000010728
Rergl
RERG like
chr2_-_184993341 5.62 ENSRNOT00000071580
Fam160a1
family with sequence similarity 160, member A1
chr5_-_12526962 5.56 ENSRNOT00000092104
St18
suppression of tumorigenicity 18
chr7_-_52404774 5.55 ENSRNOT00000082100
Nav3
neuron navigator 3
chr3_+_37545238 5.30 ENSRNOT00000070792
Tnfaip6
TNF alpha induced protein 6
chr3_+_45683993 4.82 ENSRNOT00000038983
Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr6_+_107603580 4.67 ENSRNOT00000036430
Dnal1
dynein, axonemal, light chain 1
chr2_+_207930796 4.63 ENSRNOT00000047827
Kcnd3
potassium voltage-gated channel subfamily D member 3
chr7_-_117978787 4.43 ENSRNOT00000074262
Zfp647
zinc finger protein 647
chr1_+_145715969 4.41 ENSRNOT00000037996
Tmc3
transmembrane channel-like 3
chr7_-_12429897 4.41 ENSRNOT00000020670
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr13_+_82355886 4.28 ENSRNOT00000076757
Sele
selectin E
chr10_-_47724499 4.13 ENSRNOT00000085011
Rnf112
ring finger protein 112
chr3_+_128756799 3.95 ENSRNOT00000049855
ENSRNOT00000042853
Plcb4
phospholipase C, beta 4
chr5_-_79874671 3.94 ENSRNOT00000084563
Tnc
tenascin C
chrX_+_24891156 3.93 ENSRNOT00000071173
Wwc3
WWC family member 3
chr14_+_22107416 3.74 ENSRNOT00000060179
ENSRNOT00000080114
Sult1d1
sulfotransferase family 1D, member 1
chr1_+_84070983 3.70 ENSRNOT00000090478
Numbl
NUMB-like, endocytic adaptor protein
chr16_+_35573058 3.69 ENSRNOT00000059580
Galntl6
polypeptide N-acetylgalactosaminyltransferase-like 6
chr10_+_69737328 3.66 ENSRNOT00000055999
ENSRNOT00000076773
Tmem132e
transmembrane protein 132E
chr16_+_23447366 3.64 ENSRNOT00000068629
Psd3
pleckstrin and Sec7 domain containing 3
chr7_+_13378338 3.63 ENSRNOT00000042747
Olr1073
olfactory receptor 1073
chr14_-_3300200 3.37 ENSRNOT00000037931
Btbd8
BTB (POZ) domain containing 8
chr3_+_20993205 3.26 ENSRNOT00000010465
Olr419
olfactory receptor 419
chr10_+_59725398 3.05 ENSRNOT00000026156
P2rx5
purinergic receptor P2X 5
chr10_+_84182118 3.01 ENSRNOT00000011027
Hoxb3
homeo box B3
chr7_-_120839577 2.92 ENSRNOT00000018526
Dmc1
DNA meiotic recombinase 1
chr1_-_72461547 2.77 ENSRNOT00000022480
Ssc5d
scavenger receptor cysteine rich family member with 5 domains
chr10_+_36517169 2.70 ENSRNOT00000040534
Olr1408
olfactory receptor 1408
chr13_-_88642011 2.70 ENSRNOT00000067037
LOC100361087
hypothetical LOC100361087
chr10_+_17542374 2.63 ENSRNOT00000064079
Fbxw11
F-box and WD repeat domain containing 11
chr3_+_145764932 2.49 ENSRNOT00000075257
AABR07054264.1

chr10_-_12674077 2.48 ENSRNOT00000041353
Olr1376
olfactory receptor 1376
chr11_+_43394618 2.46 ENSRNOT00000051112
Olr1543
olfactory receptor 1543
chr1_+_199351628 2.39 ENSRNOT00000078578
Bckdk
branched chain ketoacid dehydrogenase kinase
chr8_-_43443531 2.38 ENSRNOT00000007901
LOC103693060
olfactory receptor 148-like
chr2_+_40554146 2.31 ENSRNOT00000015138
Pde4d
phosphodiesterase 4D
chr15_-_12889102 2.23 ENSRNOT00000061214
ENSRNOT00000084687
RGD1306063
similar to HT021
chr7_-_114848414 2.17 ENSRNOT00000032620
Slc45a4
solute carrier family 45, member 4
chr20_+_3830164 2.07 ENSRNOT00000045533
ENSRNOT00000084117
Col11a2
collagen type XI alpha 2 chain
chr2_-_149444548 2.01 ENSRNOT00000018600
P2ry12
purinergic receptor P2Y12
chr19_-_38321528 1.98 ENSRNOT00000031977
Smpd3
sphingomyelin phosphodiesterase 3
chr15_-_100348760 1.92 ENSRNOT00000085607
AABR07019341.1

chr3_+_172155496 1.83 ENSRNOT00000066279
Stx16
syntaxin 16
chr2_+_115290243 1.82 ENSRNOT00000074802
LOC100910153
olfactory receptor 149-like
chr6_-_76552559 1.80 ENSRNOT00000065230
Ralgapa1
Ral GTPase activating protein catalytic alpha subunit 1
chrX_+_156319687 1.80 ENSRNOT00000091147
ENSRNOT00000079378
Fam3a
family with sequence similarity 3, member A
chr4_-_170783725 1.75 ENSRNOT00000072528
Wbp11
WW domain binding protein 11
chr1_+_168844875 1.70 ENSRNOT00000051398
AC107531.1

chr8_+_41302631 1.64 ENSRNOT00000076963
LOC100910822
olfactory receptor 143-like
chr11_+_43309759 1.61 ENSRNOT00000040089
Olr1539
olfactory receptor 1539
chr19_-_22632071 1.59 ENSRNOT00000077275
Gpt2
glutamic--pyruvic transaminase 2
chr3_+_73307900 1.55 ENSRNOT00000051690
Olr469
olfactory receptor 469
chr9_+_16302578 1.52 ENSRNOT00000021762
Gltscr1l
GLTSCR1-like
chr3_+_102947730 1.51 ENSRNOT00000071260
Olr773
olfactory receptor 773
chr8_+_42663633 1.50 ENSRNOT00000048537
Olr1266
olfactory receptor 1266
chrX_-_83864150 1.43 ENSRNOT00000073734
Obp1f
odorant binding protein I f
chr12_-_38504774 1.39 ENSRNOT00000011286
B3gnt4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chrX_+_122938009 1.36 ENSRNOT00000089266
ENSRNOT00000017550
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr4_+_7257752 1.36 ENSRNOT00000088357
Tmub1
transmembrane and ubiquitin-like domain containing 1
chr1_+_230450529 1.36 ENSRNOT00000045383
Olr371
olfactory receptor 371
chr1_-_205630073 1.35 ENSRNOT00000037064
Tex36
testis expressed 36
chr1_+_150225373 1.30 ENSRNOT00000051266
Olr30
olfactory receptor 30
chrX_+_1787266 1.25 ENSRNOT00000011183
Ndufb11
NADH:ubiquinone oxidoreductase subunit B11
chr15_+_27400717 1.21 ENSRNOT00000047008
Olr1620
olfactory receptor 1620
chr1_-_238381871 1.19 ENSRNOT00000077601
Tmc1
transmembrane channel-like 1
chr3_+_102579446 1.16 ENSRNOT00000047138
Olr754
olfactory receptor 754
chr20_-_5754773 1.14 ENSRNOT00000035977
Ip6k3
inositol hexakisphosphate kinase 3
chr3_+_72990358 1.13 ENSRNOT00000091920
Olr444
olfactory receptor 444
chr7_-_118518193 1.12 ENSRNOT00000075636
LOC102555083
zinc finger protein 250-like
chr3_-_39596718 1.11 ENSRNOT00000006784
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr5_-_59266293 1.04 ENSRNOT00000050490
Olr836
olfactory receptor 836
chr10_-_12818137 1.01 ENSRNOT00000060972
Olr1382
olfactory receptor 1382
chr13_+_106751625 0.97 ENSRNOT00000004992
Ush2a
usherin
chr8_+_43382176 0.94 ENSRNOT00000047759
Olr1311
olfactory receptor 1311
chr13_+_56096834 0.90 ENSRNOT00000035129
Dennd1b
DENN domain containing 1B
chr17_+_30556884 0.90 ENSRNOT00000080929
ENSRNOT00000022022
Eci2
enoyl-CoA delta isomerase 2
chr2_+_196594303 0.89 ENSRNOT00000064442
ENSRNOT00000044738
Arnt
aryl hydrocarbon receptor nuclear translocator
chr18_+_80939875 0.88 ENSRNOT00000021729
Zadh2
zinc binding alcohol dehydrogenase, domain containing 2
chr3_-_151724654 0.88 ENSRNOT00000026964
Rbm39
RNA binding motif protein 39
chr10_+_56260514 0.88 ENSRNOT00000016177
Sox15
SRY box 15
chr1_+_230030914 0.87 ENSRNOT00000075730
Olr354
olfactory receptor 354
chr1_-_228263198 0.87 ENSRNOT00000028572
Olr1874
olfactory receptor 1874
chr3_+_15895191 0.86 ENSRNOT00000047879
Olr400
olfactory receptor 400
chr5_+_137564607 0.85 ENSRNOT00000075742
LOC100912529
olfactory receptor 2B6-like
chr1_+_17602281 0.84 ENSRNOT00000075461
LOC103690149
jouberin-like
chr3_-_173839433 0.83 ENSRNOT00000075547
AC127963.1

chr3_+_78876609 0.82 ENSRNOT00000049936
Olr726
olfactory receptor 726
chr8_-_18062971 0.80 ENSRNOT00000045739
Olr1139
olfactory receptor 1139
chr1_+_164425475 0.80 ENSRNOT00000023386
Klhl35
kelch-like family member 35
chr11_+_43161181 0.79 ENSRNOT00000071470
Olr1530
olfactory receptor 1530
chr8_+_43355060 0.78 ENSRNOT00000043206
Olr1309
olfactory receptor 1309
chrX_+_74165187 0.71 ENSRNOT00000003973
Cdx4
caudal type homeo box 4
chr7_-_13588411 0.70 ENSRNOT00000088783
Olr1083
olfactory receptor 1083
chr3_-_152259156 0.66 ENSRNOT00000065729
LOC100910882
RNA-binding protein 39-like
chrX_-_76708878 0.65 ENSRNOT00000045534
Atrx
ATRX, chromatin remodeler
chr19_+_683484 0.64 ENSRNOT00000090332
Terb1
telomere repeat binding bouquet formation protein 1
chr3_+_55910177 0.63 ENSRNOT00000009969
Klhl41
kelch-like family member 41
chr11_+_43143882 0.60 ENSRNOT00000041445
Olr1528
olfactory receptor 1528
chr17_-_57816256 0.59 ENSRNOT00000051570
LOC103694120
isopentenyl-diphosphate delta-isomerase 2-like
chr11_+_43476319 0.59 ENSRNOT00000044928
Olr1548
olfactory receptor 1548
chr14_-_12387102 0.58 ENSRNOT00000038872
Bmp3
bone morphogenetic protein 3
chr3_-_23353425 0.57 ENSRNOT00000019703
Golga1
golgin A1
chr18_+_40883224 0.53 ENSRNOT00000039733
Lvrn
laeverin
chr2_+_196334626 0.51 ENSRNOT00000050914
ENSRNOT00000028645
ENSRNOT00000090729
Sema6c
semaphorin 6C
chr10_+_60043848 0.49 ENSRNOT00000080593
AABR07029918.1

chr16_+_55152748 0.48 ENSRNOT00000000121
Fgf20
fibroblast growth factor 20
chr3_+_20965751 0.44 ENSRNOT00000010450
Olr417
olfactory receptor 417
chr10_-_16045835 0.42 ENSRNOT00000064832
Cpeb4
cytoplasmic polyadenylation element binding protein 4
chr10_-_62366044 0.41 ENSRNOT00000045673
Olr1474
olfactory receptor 1474
chr10_-_12644292 0.40 ENSRNOT00000041612
Olr1375
olfactory receptor 1375
chr10_-_12370656 0.39 ENSRNOT00000060995
Olr1362
olfactory receptor 1362
chr7_-_13531526 0.37 ENSRNOT00000048054
Olr1081
olfactory receptor 1081
chr1_+_168830222 0.36 ENSRNOT00000050333
Olr122
olfactory receptor 122
chr16_-_75028977 0.36 ENSRNOT00000058071
Defb13
defensin beta 13
chr8_+_5790034 0.35 ENSRNOT00000061887
Mmp27
matrix metallopeptidase 27
chr18_+_70192493 0.35 ENSRNOT00000020472
Cxxc1
CXXC finger protein 1
chr7_+_125576327 0.33 ENSRNOT00000016679
Prr5
proline rich 5
chr10_-_60772313 0.32 ENSRNOT00000050847
Olr1504
olfactory receptor 1504
chr10_-_110308514 0.32 ENSRNOT00000054927
Tex19.2
testis expressed gene 19.2
chr3_+_65816569 0.32 ENSRNOT00000079672
Ube2e3
ubiquitin-conjugating enzyme E2E 3
chr8_-_43082948 0.31 ENSRNOT00000072050
LOC100910667
olfactory receptor 8G5-like
chr8_+_41252456 0.28 ENSRNOT00000071683
Olr1220
olfactory receptor 1220
chr10_-_12777245 0.25 ENSRNOT00000041708
Olr1380
olfactory receptor 1380
chr3_-_66335869 0.21 ENSRNOT00000079781
ENSRNOT00000043238
ENSRNOT00000073412
ENSRNOT00000057878
ENSRNOT00000079212
Cerkl
ceramide kinase-like
chr3_-_73854363 0.20 ENSRNOT00000051169
Olr496
olfactory receptor 496
chr3_-_74575010 0.19 ENSRNOT00000045231
Olr533
olfactory receptor 533
chr11_+_43194348 0.18 ENSRNOT00000075303
Olr1532
olfactory receptor 1532
chr1_+_213258684 0.18 ENSRNOT00000091678
LOC103690271
olfactory receptor 13A1-like
chr3_+_20878701 0.17 ENSRNOT00000046877
Olr413
olfactory receptor 413
chr3_+_21016266 0.17 ENSRNOT00000010473
Olr420
olfactory receptor 420
chr11_-_72086743 0.17 ENSRNOT00000072173
Pigz
phosphatidylinositol glycan anchor biosynthesis, class Z
chr1_+_230377079 0.13 ENSRNOT00000042937
Olr367
olfactory receptor 367
chr7_-_13553963 0.10 ENSRNOT00000079450
Olr1082
olfactory receptor 1082
chrX_-_76924362 0.09 ENSRNOT00000078997
Atrx
ATRX, chromatin remodeler
chr1_-_59903339 0.08 ENSRNOT00000039037
Fpr-rs3
formyl peptide receptor, related sequence 3
chr2_-_210088949 0.07 ENSRNOT00000070994
Rbm15
RNA binding motif protein 15
chr10_+_60728160 0.06 ENSRNOT00000041085
Olr1501
olfactory receptor 1501
chr12_+_19561347 0.05 ENSRNOT00000060025
RGD1562319
similar to family with sequence similarity 55, member C
chr3_-_76085971 0.04 ENSRNOT00000007679
Olr601
olfactory receptor 601
chr4_+_1482486 0.04 ENSRNOT00000035054
Olr1236
olfactory receptor 1236

Network of associatons between targets according to the STRING database.

First level regulatory network of Atoh1_Bhlhe23

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.6 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
3.8 11.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
3.6 18.2 GO:0034334 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334)
2.7 19.0 GO:0099525 positive regulation of synaptic vesicle priming(GO:0010808) presynaptic dense core granule exocytosis(GO:0099525)
2.1 8.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
2.1 6.2 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
1.5 22.9 GO:0048681 negative regulation of axon regeneration(GO:0048681)
1.5 7.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
1.3 16.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.2 3.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
1.1 12.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
1.0 3.9 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.8 6.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000) very long-chain fatty acid catabolic process(GO:0042760)
0.8 21.3 GO:0010842 retina layer formation(GO:0010842)
0.8 2.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.8 3.0 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.7 2.2 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.7 2.8 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.7 2.0 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.7 3.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.6 7.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.5 30.9 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.5 3.7 GO:0000103 sulfate assimilation(GO:0000103)
0.4 2.9 GO:0042148 strand invasion(GO:0042148)
0.4 4.6 GO:0098915 potassium ion export across plasma membrane(GO:0097623) membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.4 3.9 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.3 1.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 2.1 GO:0060023 soft palate development(GO:0060023)
0.3 2.0 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.3 6.8 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.3 1.6 GO:0042851 L-alanine metabolic process(GO:0042851)
0.2 0.7 GO:0035128 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.2 1.2 GO:0060005 vestibular reflex(GO:0060005)
0.2 4.8 GO:0097062 dendritic spine maintenance(GO:0097062)
0.2 10.7 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.2 2.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.2 6.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.2 1.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 3.9 GO:0007602 phototransduction(GO:0007602)
0.2 4.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 3.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 4.3 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.1 2.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 1.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 10.9 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 4.1 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.1 1.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 5.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.9 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.1 0.9 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1 0.6 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.1 2.0 GO:0030728 ovulation(GO:0030728)
0.0 0.6 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 1.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 5.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.9 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 1.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 7.0 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 1.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.6 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 1.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.5 GO:0060043 regulation of cardiac muscle cell proliferation(GO:0060043)
0.0 0.7 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 20.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 19.0 GO:0044305 calyx of Held(GO:0044305)
0.8 17.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.7 2.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.6 4.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.5 2.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.4 18.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 2.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 13.8 GO:0032420 stereocilium(GO:0032420)
0.3 14.6 GO:0031201 SNARE complex(GO:0031201)
0.2 0.7 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.2 4.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 6.2 GO:0030673 axolemma(GO:0030673)
0.2 3.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 3.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 6.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 4.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 32.3 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.6 GO:0070187 telosome(GO:0070187)
0.1 0.6 GO:0031143 pseudopodium(GO:0031143)
0.1 8.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 0.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 41.2 GO:0005794 Golgi apparatus(GO:0005794)
0.0 2.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 4.8 GO:0043679 axon terminus(GO:0043679)
0.0 0.9 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 2.9 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 1.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 11.3 GO:0030425 dendrite(GO:0030425)
0.0 1.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 4.3 GO:0016607 nuclear speck(GO:0016607)
0.0 0.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 30.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
2.1 19.0 GO:0019992 diacylglycerol binding(GO:0019992)
2.1 22.9 GO:0039706 co-receptor binding(GO:0039706)
2.1 16.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.7 8.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.4 18.2 GO:0045294 alpha-catenin binding(GO:0045294)
1.3 12.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.9 4.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.9 16.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.7 2.2 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.6 3.9 GO:0045545 syndecan binding(GO:0045545)
0.5 3.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.5 1.6 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.5 6.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 2.9 GO:0000150 recombinase activity(GO:0000150)
0.3 1.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.3 3.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 4.3 GO:0033691 sialic acid binding(GO:0033691)
0.3 0.9 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.3 2.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 2.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 11.3 GO:0015485 cholesterol binding(GO:0015485)
0.2 0.9 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2 0.9 GO:0036132 13-prostaglandin reductase activity(GO:0036132)
0.2 4.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 2.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 10.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 5.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 12.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 3.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.2 7.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.6 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.1 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 3.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 7.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 2.8 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 5.7 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 3.9 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 3.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 33.7 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 11.3 GO:0005549 odorant binding(GO:0005549)
0.0 1.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.0 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 3.1 GO:0003924 GTPase activity(GO:0003924)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.7 PID ARF6 PATHWAY Arf6 signaling events
0.2 16.6 PID FGF PATHWAY FGF signaling pathway
0.1 4.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 3.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 6.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 11.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 2.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 19.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 0.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 19.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.7 36.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.6 22.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.5 14.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.4 16.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 6.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 3.9 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.3 6.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 4.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 8.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 2.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.2 2.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 17.1 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.1 2.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 11.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 4.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 3.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 2.6 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells