ISMARA results: Ascl2

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Ascl2

Z-value: 1.17

Motif logo

Transcription factors associated with Ascl2

Gene Symbol	Gene ID	Gene Info
Ascl2 NCBI RGD Ensembl	ENSRNOG00000020434	achaete-scute family bHLH transcription factor 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Ascl2	rn6_v1_chr1_-_216156409_216156409	-0.15	8.0e-03	Click!

Activity profile of Ascl2 motif

Sorted Z-values of Ascl2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_+_87774552 Show fit	71.68	ENSRNOT00000044342	Krtap9-1 NCBI RGD Ensembl Show fit	keratin associated protein 9-1
chr1_+_100199057 Show fit	61.16	ENSRNOT00000025831	Klk1 NCBI RGD Ensembl Show fit	kallikrein 1
chr10_+_87759769 Show fit	50.05	ENSRNOT00000017378 ENSRNOT00000046526	Krtap9-1 NCBI RGD Ensembl Show fit	keratin associated protein 9-1
chr10_+_87782376 Show fit	42.04	ENSRNOT00000017415	LOC680396 NCBI RGD Ensembl Show fit	hypothetical protein LOC680396
chr12_+_24761210 Show fit	40.28	ENSRNOT00000002003	Cldn4 NCBI RGD Ensembl Show fit	claudin 4
chr3_+_119015412 Show fit	38.49	ENSRNOT00000013605	Slc27a2 NCBI RGD Ensembl Show fit	solute carrier family 27 member 2
chr19_-_43911057 Show fit	32.32	ENSRNOT00000026017	Ctrb1 NCBI RGD Ensembl Show fit	chymotrypsinogen B1
chr5_-_151459037 Show fit	32.23	ENSRNOT00000064472 ENSRNOT00000087836	Sytl1 NCBI RGD Ensembl Show fit	synaptotagmin-like 1
chr10_+_87788458 Show fit	31.54	ENSRNOT00000042020	LOC100910814 NCBI RGD Ensembl Show fit	keratin-associated protein 9-1-like
chr3_+_119014620 Show fit	31.20	ENSRNOT00000067700	Slc27a2 NCBI RGD Ensembl Show fit	solute carrier family 27 member 2
chr4_-_10517832 Show fit	31.11	ENSRNOT00000039953 ENSRNOT00000083964	Gsap NCBI RGD Ensembl Show fit	gamma-secretase activating protein
chr10_-_87564327 Show fit	26.67	ENSRNOT00000064760 ENSRNOT00000068237	LOC680160 NCBI RGD Ensembl Show fit	similar to keratin associated protein 4-7
chr9_+_9721105 Show fit	26.49	ENSRNOT00000073042 ENSRNOT00000075494	C3 NCBI RGD Ensembl Show fit	complement C3
chr6_-_138508753 Show fit	26.06	ENSRNOT00000006888	Ighm NCBI RGD Ensembl Show fit	immunoglobulin heavy constant mu
chr17_-_43543172 Show fit	25.47	ENSRNOT00000080684 ENSRNOT00000029626 ENSRNOT00000082719	Slc17a3 NCBI RGD Ensembl Show fit	solute carrier family 17 member 3
chr1_-_8751198 Show fit	25.10	ENSRNOT00000030511	Adgrg6 NCBI RGD Ensembl Show fit	adhesion G protein-coupled receptor G6
chr1_-_260638816 Show fit	24.87	ENSRNOT00000065632 ENSRNOT00000017938 ENSRNOT00000077962	Pik3ap1 NCBI RGD Ensembl Show fit	phosphoinositide-3-kinase adaptor protein 1
chr3_-_172537877 Show fit	24.59	ENSRNOT00000072069	Ctsz NCBI RGD Ensembl Show fit	cathepsin Z
chr11_-_90406797 Show fit	24.31	ENSRNOT00000073049	Snai2 NCBI RGD Ensembl Show fit	snail family transcriptional repressor 2
chr4_-_157252565 Show fit	23.90	ENSRNOT00000079947	Ptpn6 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 6
chr14_-_80973456 Show fit	23.25	ENSRNOT00000013257	Hgfac NCBI RGD Ensembl Show fit	HGF activator
chr4_-_157252104 Show fit	22.70	ENSRNOT00000082739	Ptpn6 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 6
chr12_-_21832813 Show fit	22.60	ENSRNOT00000075280	Cldn3 NCBI RGD Ensembl Show fit	claudin 3
chr1_+_101214593 Show fit	22.46	ENSRNOT00000028086	Tead2 NCBI RGD Ensembl Show fit	TEA domain transcription factor 2
chr13_-_91427575 Show fit	22.32	ENSRNOT00000012092	Apcs NCBI RGD Ensembl Show fit	amyloid P component, serum
chr14_+_3058993 Show fit	21.90	ENSRNOT00000002807	Gfi1 NCBI RGD Ensembl Show fit	growth factor independent 1 transcriptional repressor
chr18_+_56071478 Show fit	21.80	ENSRNOT00000025344 ENSRNOT00000025354	Cd74 NCBI RGD Ensembl Show fit	CD74 molecule
chr2_+_32820322 Show fit	21.65	ENSRNOT00000013768	Cd180 NCBI RGD Ensembl Show fit	CD180 molecule
chr8_-_50539331 Show fit	20.73	ENSRNOT00000088997	AABR07073400.1 NCBI RGD Ensembl Show fit
chr7_+_94130852 Show fit	20.67	ENSRNOT00000011485	Mal2 NCBI RGD Ensembl Show fit	mal, T-cell differentiation protein 2
chr1_-_53087474 Show fit	20.33	ENSRNOT00000017302	Ccr6 NCBI RGD Ensembl Show fit	C-C motif chemokine receptor 6
chr1_+_86938138 Show fit	19.94	ENSRNOT00000075601	Ccer2 NCBI RGD Ensembl Show fit	coiled-coil glutamate-rich protein 2
chr6_-_141291347 Show fit	19.53	ENSRNOT00000008333	AABR07065789.1 NCBI RGD Ensembl Show fit
chr1_+_203160323 Show fit	19.35	ENSRNOT00000027919	AABR07005844.1 NCBI RGD Ensembl Show fit
chr5_-_155772040 Show fit	19.27	ENSRNOT00000036788	Cela3b NCBI RGD Ensembl Show fit	chymotrypsin-like elastase family, member 3B
chr3_-_60166013 Show fit	19.20	ENSRNOT00000024922	Wipf1 NCBI RGD Ensembl Show fit	WAS/WASL interacting protein family, member 1
chr14_-_45797887 Show fit	18.63	ENSRNOT00000029209	Tbc1d1 NCBI RGD Ensembl Show fit	TBC1 domain family member 1
chr16_-_19399851 Show fit	18.48	ENSRNOT00000089056 ENSRNOT00000021073	Tpm4 NCBI RGD Ensembl Show fit	tropomyosin 4
chr12_+_2180150 Show fit	18.41	ENSRNOT00000001322	Stxbp2 NCBI RGD Ensembl Show fit	syntaxin binding protein 2
chr3_+_19772056 Show fit	18.41	ENSRNOT00000044455	AABR07051708.1 NCBI RGD Ensembl Show fit
chr11_-_38088753 Show fit	18.13	ENSRNOT00000002713	Tmprss2 NCBI RGD Ensembl Show fit	transmembrane protease, serine 2
chr7_-_107634287 Show fit	18.01	ENSRNOT00000093672 ENSRNOT00000087116	Sla NCBI RGD Ensembl Show fit	src-like adaptor
chr7_-_71226150 Show fit	17.89	ENSRNOT00000005875	RGD1561812 NCBI RGD Ensembl Show fit	similar to Retinol dehydrogenase type II (RODH II) (29 k-protein)
chr1_-_141188031 Show fit	17.85	ENSRNOT00000044567	Polg NCBI RGD Ensembl Show fit	DNA polymerase gamma, catalytic subunit
chr19_-_19727081 Show fit	17.74	ENSRNOT00000020700	Adcy7 NCBI RGD Ensembl Show fit	adenylate cyclase 7
chr7_-_143016040 Show fit	17.56	ENSRNOT00000029697	Krt80 NCBI RGD Ensembl Show fit	keratin 80
chr9_-_9675110 Show fit	17.07	ENSRNOT00000073294	Vav1 NCBI RGD Ensembl Show fit	vav guanine nucleotide exchange factor 1
chr2_+_54466280 Show fit	16.99	ENSRNOT00000033112	C6 NCBI RGD Ensembl Show fit	complement C6
chr6_-_142060032 Show fit	16.82	ENSRNOT00000064717	AABR07065811.1 NCBI RGD Ensembl Show fit
chr10_+_86399827 Show fit	16.80	ENSRNOT00000009299	Grb7 NCBI RGD Ensembl Show fit	growth factor receptor bound protein 7
chr7_-_3386522 Show fit	16.79	ENSRNOT00000010760	Mettl7b NCBI RGD Ensembl Show fit	methyltransferase like 7B
chr2_-_202816562 Show fit	16.49	ENSRNOT00000020401	Fam46c NCBI RGD Ensembl Show fit	family with sequence similarity 46, member C
chr6_-_143065639 Show fit	16.47	ENSRNOT00000070923	AABR07065827.1 NCBI RGD Ensembl Show fit
chr5_+_149047681 Show fit	16.31	ENSRNOT00000015198	Laptm5 NCBI RGD Ensembl Show fit	lysosomal protein transmembrane 5
chr3_-_81282157 Show fit	16.18	ENSRNOT00000051258	Large2 NCBI RGD Ensembl Show fit	LARGE xylosyl- and glucuronyltransferase 2
chr13_+_89805962 Show fit	16.06	ENSRNOT00000074035	Tstd1 NCBI RGD Ensembl Show fit	thiosulfate sulfurtransferase like domain containing 1
chr9_-_52912293 Show fit	16.04	ENSRNOT00000005228	Slc40a1 NCBI RGD Ensembl Show fit	solute carrier family 40 member 1
chr6_-_138550576 Show fit	15.97	ENSRNOT00000075284	AABR07065645.1 NCBI RGD Ensembl Show fit
chr6_+_139158334 Show fit	15.89	ENSRNOT00000089227	AABR07065673.1 NCBI RGD Ensembl Show fit
chr1_+_226687258 Show fit	15.87	ENSRNOT00000079679	Vwce NCBI RGD Ensembl Show fit	von Willebrand factor C and EGF domains
chr12_-_22127021 Show fit	15.83	ENSRNOT00000076261	Sap25 NCBI RGD Ensembl Show fit	Sin3A-associated protein 25
chr12_-_22126350 Show fit	15.69	ENSRNOT00000076328	Sap25 NCBI RGD Ensembl Show fit	Sin3A-associated protein 25
chr7_-_51353068 Show fit	15.33	ENSRNOT00000008222	Pawr NCBI RGD Ensembl Show fit	pro-apoptotic WT1 regulator
chr1_-_54748763 Show fit	15.31	ENSRNOT00000074549	LOC100911027 NCBI RGD Ensembl Show fit	protein MAL2-like
chr1_-_75154325 Show fit	15.03	ENSRNOT00000074520	RGD1564801 NCBI RGD Ensembl Show fit	similar to hepatic multiple inositol polyphosphate phosphatase
chr13_-_80745347 Show fit	14.73	ENSRNOT00000041908	Fmo1 NCBI RGD Ensembl Show fit	flavin containing monooxygenase 1
chr1_+_251045440 Show fit	14.35	ENSRNOT00000015017	Minpp1 NCBI RGD Ensembl Show fit	multiple inositol-polyphosphate phosphatase 1
chr12_+_25119355 Show fit	14.19	ENSRNOT00000034629	Lat2 NCBI RGD Ensembl Show fit	linker for activation of T cells family, member 2
chr4_-_28437676 Show fit	14.18	ENSRNOT00000012995	Hepacam2 NCBI RGD Ensembl Show fit	HEPACAM family member 2
chr12_-_22126858 Show fit	14.15	ENSRNOT00000084480	Sap25 NCBI RGD Ensembl Show fit	Sin3A-associated protein 25
chr11_-_11585765 Show fit	14.02	ENSRNOT00000066439	Robo2 NCBI RGD Ensembl Show fit	roundabout guidance receptor 2
chr9_-_14668297 Show fit	13.99	ENSRNOT00000042404	Treml2 NCBI RGD Ensembl Show fit	triggering receptor expressed on myeloid cells-like 2
chr5_+_142845114 Show fit	13.97	ENSRNOT00000039870	Yrdc NCBI RGD Ensembl Show fit	yrdC N(6)-threonylcarbamoyltransferase domain containing
chr14_-_82287706 Show fit	13.91	ENSRNOT00000080695	Fgfr3 NCBI RGD Ensembl Show fit	fibroblast growth factor receptor 3
chr19_+_25391700 Show fit	13.86	ENSRNOT00000011163	LOC100359539 NCBI RGD Ensembl Show fit	ribonucleotide reductase M2 polypeptide
chr6_-_141488290 Show fit	13.79	ENSRNOT00000067336	AABR07065792.1 NCBI RGD Ensembl Show fit
chr4_+_157126935 Show fit	13.69	ENSRNOT00000056051	C1r NCBI RGD Ensembl Show fit	complement C1r
chr4_-_89695928 Show fit	13.68	ENSRNOT00000039316	Gprin3 NCBI RGD Ensembl Show fit	GPRIN family member 3
chr4_-_170620703 Show fit	13.59	ENSRNOT00000011930	Plbd1 NCBI RGD Ensembl Show fit	phospholipase B domain containing 1
chr10_+_103713045 Show fit	13.32	ENSRNOT00000004351	Slc9a3r1 NCBI RGD Ensembl Show fit	SLC9A3 regulator 1
chr1_-_199439210 Show fit	13.29	ENSRNOT00000026699	Pycard NCBI RGD Ensembl Show fit	PYD and CARD domain containing
chr5_-_134526089 Show fit	12.83	ENSRNOT00000013321	Cyp4b1 NCBI RGD Ensembl Show fit	cytochrome P450, family 4, subfamily b, polypeptide 1
chr7_-_3342491 Show fit	12.74	ENSRNOT00000081756	Rdh5 NCBI RGD Ensembl Show fit	retinol dehydrogenase 5
chr1_+_22332090 Show fit	12.63	ENSRNOT00000091252	AABR07000663.1 NCBI RGD Ensembl Show fit	trace amine-associated receptor 8c (Taar8c), mRNA
chrX_+_70461718 Show fit	12.63	ENSRNOT00000078233 ENSRNOT00000003789	Kif4a NCBI RGD Ensembl Show fit	kinesin family member 4A
chr7_-_107616038 Show fit	12.52	ENSRNOT00000088752	Sla NCBI RGD Ensembl Show fit	src-like adaptor
chr1_+_85003280 Show fit	12.41	ENSRNOT00000057122	Fcgbp NCBI RGD Ensembl Show fit	Fc fragment of IgG binding protein
chr20_+_5446104 Show fit	12.29	ENSRNOT00000000550	B3galt4 NCBI RGD Ensembl Show fit	Beta-1,3-galactosyltransferase 4
chr16_+_20426566 Show fit	12.26	ENSRNOT00000026225	Ifi30 NCBI RGD Ensembl Show fit	IFI30, lysosomal thiol reductase
chr16_+_20555395 Show fit	12.26	ENSRNOT00000026652	Gdf15 NCBI RGD Ensembl Show fit	growth differentiation factor 15
chr16_+_20110148 Show fit	12.25	ENSRNOT00000080146 ENSRNOT00000025312	Jak3 NCBI RGD Ensembl Show fit	Janus kinase 3
chr2_-_219262901 Show fit	12.22	ENSRNOT00000037068	Gpr88 NCBI RGD Ensembl Show fit	G-protein coupled receptor 88
chr19_+_37476095 Show fit	12.05	ENSRNOT00000092794 ENSRNOT00000023130	Hsd11b2 NCBI RGD Ensembl Show fit	hydroxysteroid 11-beta dehydrogenase 2
chr9_-_71445739 Show fit	12.05	ENSRNOT00000019698	Fzd5 NCBI RGD Ensembl Show fit	frizzled class receptor 5
chr1_+_145715969 Show fit	11.95	ENSRNOT00000037996	Tmc3 NCBI RGD Ensembl Show fit	transmembrane channel-like 3
chr17_+_76306585 Show fit	11.88	ENSRNOT00000065978	Dhtkd1 NCBI RGD Ensembl Show fit	dehydrogenase E1 and transketolase domain containing 1
chr1_+_137014272 Show fit	11.84	ENSRNOT00000014802	Akap13 NCBI RGD Ensembl Show fit	A-kinase anchoring protein 13
chr14_-_33150509 Show fit	11.76	ENSRNOT00000002837	Rest NCBI RGD Ensembl Show fit	RE1-silencing transcription factor
chr8_+_5993941 Show fit	11.44	ENSRNOT00000014065	Tmem123 NCBI RGD Ensembl Show fit	transmembrane protein 123
chr3_+_164822111 Show fit	11.43	ENSRNOT00000014568	Pard6b NCBI RGD Ensembl Show fit	par-6 family cell polarity regulator beta
chr17_-_43776460 Show fit	11.41	ENSRNOT00000089055	Hist2h3c2 NCBI RGD Ensembl Show fit	histone cluster 2, H3c2
chr1_-_98570949 Show fit	11.40	ENSRNOT00000033648	Siglec5 NCBI RGD Ensembl Show fit	sialic acid binding Ig-like lectin 5
chr6_-_138536321 Show fit	11.35	ENSRNOT00000077743	AABR07065643.1 NCBI RGD Ensembl Show fit
chr6_+_10912383 Show fit	11.23	ENSRNOT00000061747 ENSRNOT00000086247	Ttc7a NCBI RGD Ensembl Show fit	tetratricopeptide repeat domain 7A
chr6_-_138744480 Show fit	11.12	ENSRNOT00000089387	AABR07065651.5 NCBI RGD Ensembl Show fit
chr20_-_22004209 Show fit	11.08	ENSRNOT00000086250 ENSRNOT00000068778	Rtkn2 NCBI RGD Ensembl Show fit	rhotekin 2
chr1_+_107344904 Show fit	10.99	ENSRNOT00000082582	Gas2 NCBI RGD Ensembl Show fit	growth arrest-specific 2
chr1_-_213987053 Show fit	10.98	ENSRNOT00000072774	LOC100911519 NCBI RGD Ensembl Show fit	p53-induced protein with a death domain-like
chr9_+_100285804 Show fit	10.93	ENSRNOT00000079305	Agxt NCBI RGD Ensembl Show fit	alanine-glyoxylate aminotransferase
chr4_+_14001761 Show fit	10.81	ENSRNOT00000076519	Cd36 NCBI RGD Ensembl Show fit	CD36 molecule
chr1_+_192233910 Show fit	10.81	ENSRNOT00000016418 ENSRNOT00000016442	Prkcb NCBI RGD Ensembl Show fit	protein kinase C, beta
chr10_-_31419235 Show fit	10.76	ENSRNOT00000059496	Cyfip2 NCBI RGD Ensembl Show fit	cytoplasmic FMR1 interacting protein 2
chr9_+_94425252 Show fit	10.56	ENSRNOT00000064965 ENSRNOT00000076099	Gigyf2 NCBI RGD Ensembl Show fit	GRB10 interacting GYF protein 2
chr4_-_100099517 Show fit	10.43	ENSRNOT00000014277	Atoh8 NCBI RGD Ensembl Show fit	atonal bHLH transcription factor 8
chr20_+_8165307 Show fit	10.31	ENSRNOT00000000637	Pim1 NCBI RGD Ensembl Show fit	Pim-1 proto-oncogene, serine/threonine kinase
chr4_-_180505916 Show fit	10.29	ENSRNOT00000086465	AABR07062512.1 NCBI RGD Ensembl Show fit
chr3_+_161298962 Show fit	10.21	ENSRNOT00000066028	Ctsa NCBI RGD Ensembl Show fit	cathepsin A
chr1_-_169463760 Show fit	10.19	ENSRNOT00000023100	Trim30c NCBI RGD Ensembl Show fit	tripartite motif-containing 30C
chr4_-_62438958 Show fit	10.16	ENSRNOT00000014010	Wdr91 NCBI RGD Ensembl Show fit	WD repeat domain 91
chr20_+_3677474 Show fit	10.03	ENSRNOT00000047663	Mt1m NCBI RGD Ensembl Show fit	metallothionein 1M
chr5_-_155258392 Show fit	9.99	ENSRNOT00000017065	C1qc NCBI RGD Ensembl Show fit	complement C1q C chain
chr11_+_17538063 Show fit	9.98	ENSRNOT00000031889 ENSRNOT00000090878	Chodl NCBI RGD Ensembl Show fit	chondrolectin
chr1_-_42971208 Show fit	9.95	ENSRNOT00000088535	Gm5414 NCBI RGD Ensembl Show fit	predicted gene 5414
chr5_+_157222636 Show fit	9.92	ENSRNOT00000022579	Pla2g2d NCBI RGD Ensembl Show fit	phospholipase A2, group IID
chr3_-_46621873 Show fit	9.92	ENSRNOT00000011003	Pla2r1 NCBI RGD Ensembl Show fit	phospholipase A2 receptor 1
chr2_-_29121104 Show fit	9.86	ENSRNOT00000020543	Tnpo1 NCBI RGD Ensembl Show fit	transportin 1
chr20_-_3397039 Show fit	9.82	ENSRNOT00000001084 ENSRNOT00000085259	Ppp1r18 NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory subunit 18
chr8_-_62616828 Show fit	9.76	ENSRNOT00000068340	Arid3b NCBI RGD Ensembl Show fit	AT-rich interaction domain 3B
chr1_-_64446818 Show fit	9.73	ENSRNOT00000081980	Myadm NCBI RGD Ensembl Show fit	myeloid-associated differentiation marker
chr10_+_14122878 Show fit	9.72	ENSRNOT00000052008	Hs3st6 NCBI RGD Ensembl Show fit	heparan sulfate-glucosamine 3-sulfotransferase 6
chr14_+_13192347 Show fit	9.70	ENSRNOT00000000092	Antxr2 NCBI RGD Ensembl Show fit	anthrax toxin receptor 2
chr1_-_88176610 Show fit	9.62	ENSRNOT00000032394	LOC100909725 NCBI RGD Ensembl Show fit	potassium channel subfamily K member 6-like
chr8_-_61917125 Show fit	9.61	ENSRNOT00000085049	RGD1305464 NCBI RGD Ensembl Show fit	similar to human chromosome 15 open reading frame 39
chr17_+_43734461 Show fit	9.59	ENSRNOT00000072564	Hist1h1d NCBI RGD Ensembl Show fit	histone cluster 1, H1d
chr12_+_9728486 Show fit	9.59	ENSRNOT00000001263	Lnx2 NCBI RGD Ensembl Show fit	ligand of numb-protein X 2
chr8_+_132828091 Show fit	9.51	ENSRNOT00000008269	Ccr9 NCBI RGD Ensembl Show fit	C-C motif chemokine receptor 9
chr4_+_88834066 Show fit	9.32	ENSRNOT00000009546	Abcg2 NCBI RGD Ensembl Show fit	ATP-binding cassette, subfamily G (WHITE), member 2
chr2_-_88113029 Show fit	9.31	ENSRNOT00000013354	Car2 NCBI RGD Ensembl Show fit	carbonic anhydrase 2
chr12_+_22165486 Show fit	9.24	ENSRNOT00000001890	Mospd3 NCBI RGD Ensembl Show fit	motile sperm domain containing 3
chr19_-_11341863 Show fit	9.24	ENSRNOT00000025694	Mt4 NCBI RGD Ensembl Show fit	metallothionein 4
chr8_+_40078269 Show fit	9.10	ENSRNOT00000044293	Siae NCBI RGD Ensembl Show fit	sialic acid acetylesterase
chr10_+_7041510 Show fit	9.03	ENSRNOT00000003514	Carhsp1 NCBI RGD Ensembl Show fit	calcium regulated heat stable protein 1
chr7_+_12146642 Show fit	9.03	ENSRNOT00000085899	Tcf3 NCBI RGD Ensembl Show fit	transcription factor 3
chr7_-_116920507 Show fit	9.02	ENSRNOT00000048363	Mroh6 NCBI RGD Ensembl Show fit	maestro heat-like repeat family member 6
chr8_+_22368745 Show fit	9.02	ENSRNOT00000049973	Slc44a2 NCBI RGD Ensembl Show fit	solute carrier family 44 member 2
chr14_-_84189266 Show fit	8.98	ENSRNOT00000005934	Tcn2 NCBI RGD Ensembl Show fit	transcobalamin 2
chr16_+_74531564 Show fit	8.94	ENSRNOT00000078971	Slc25a15 NCBI RGD Ensembl Show fit	solute carrier family 25 member 15
chr7_-_67116980 Show fit	8.93	ENSRNOT00000005798	Ppm1h NCBI RGD Ensembl Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr6_-_139654508 Show fit	8.91	ENSRNOT00000082576	AABR07065705.5 NCBI RGD Ensembl Show fit
chr3_+_7422820 Show fit	8.86	ENSRNOT00000064323	Ddx31 NCBI RGD Ensembl Show fit	DEAD-box helicase 31
chr18_+_60392376 Show fit	8.85	ENSRNOT00000023890	Nedd4l NCBI RGD Ensembl Show fit	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr6_-_138772894 Show fit	8.82	ENSRNOT00000080779	AABR07065651.1 NCBI RGD Ensembl Show fit
chr7_-_119996824 Show fit	8.81	ENSRNOT00000011079	Mfng NCBI RGD Ensembl Show fit	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr3_-_51297852 Show fit	8.75	ENSRNOT00000001607	Cobll1 NCBI RGD Ensembl Show fit	cordon-bleu WH2 repeat protein-like 1
chr7_-_2941122 Show fit	8.73	ENSRNOT00000082107	Esyt1 NCBI RGD Ensembl Show fit	extended synaptotagmin 1
chr10_-_39373437 Show fit	8.65	ENSRNOT00000058907	Slc22a5 NCBI RGD Ensembl Show fit	solute carrier family 22 member 5
chr13_+_113373578 Show fit	8.61	ENSRNOT00000009900	Plxna2 NCBI RGD Ensembl Show fit	plexin A2
chr6_-_24563246 Show fit	8.51	ENSRNOT00000074294	LOC685881 NCBI RGD Ensembl Show fit	hypothetical protein LOC685881
chr7_-_3102142 Show fit	8.49	ENSRNOT00000008018	Suox NCBI RGD Ensembl Show fit	sulfite oxidase
chr10_-_4910305 Show fit	8.47	ENSRNOT00000033122	Rmi2 NCBI RGD Ensembl Show fit	RecQ mediated genome instability 2
chr1_+_85213652 Show fit	8.41	ENSRNOT00000092044	Nccrp1 NCBI RGD Ensembl Show fit	non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr4_-_155923079 Show fit	8.38	ENSRNOT00000013308	Clec4a3 NCBI RGD Ensembl Show fit	C-type lectin domain family 4, member A3
chr8_+_48716939 Show fit	8.32	ENSRNOT00000015810	Slc37a4 NCBI RGD Ensembl Show fit	solute carrier family 37 member 4
chr9_+_20048121 Show fit	8.32	ENSRNOT00000014791	Mep1a NCBI RGD Ensembl Show fit	meprin 1 subunit alpha
chr6_+_43884678 Show fit	8.26	ENSRNOT00000091551	Rrm2 NCBI RGD Ensembl Show fit	ribonucleotide reductase regulatory subunit M2
chr19_+_30936703 Show fit	8.24	ENSRNOT00000024568	Smarca5 NCBI RGD Ensembl Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chrX_+_123404518 Show fit	8.15	ENSRNOT00000015085	Slc25a5 NCBI RGD Ensembl Show fit	solute carrier family 25 member 5
chr6_-_80334522 Show fit	8.10	ENSRNOT00000059316	Fbxo33 NCBI RGD Ensembl Show fit	F-box protein 33
chr6_-_138536162 Show fit	8.07	ENSRNOT00000083031	AABR07065643.1 NCBI RGD Ensembl Show fit
chr18_+_24708115 Show fit	8.05	ENSRNOT00000061054	Lims2 NCBI RGD Ensembl Show fit	LIM zinc finger domain containing 2
chr17_+_76079720 Show fit	8.04	ENSRNOT00000073933	Proser2 NCBI RGD Ensembl Show fit	proline and serine rich 2
chr1_-_214423881 Show fit	8.01	ENSRNOT00000025290	Pidd1 NCBI RGD Ensembl Show fit	p53-induced death domain protein 1
chr6_-_141008427 Show fit	7.94	ENSRNOT00000074472	AABR07065778.2 NCBI RGD Ensembl Show fit
chr1_-_252808380 Show fit	7.94	ENSRNOT00000025856	Ch25h NCBI RGD Ensembl Show fit	cholesterol 25-hydroxylase
chrX_+_80213332 Show fit	7.93	ENSRNOT00000042827	Sh3bgrl NCBI RGD Ensembl Show fit	SH3 domain binding glutamate-rich protein like
chr11_-_53575060 Show fit	7.89	ENSRNOT00000050142 ENSRNOT00000078221 ENSRNOT00000078434	Cd47 NCBI RGD Ensembl Show fit	Cd47 molecule
chr2_-_112831476 Show fit	7.88	ENSRNOT00000018055	Ect2 NCBI RGD Ensembl Show fit	epithelial cell transforming 2
chr16_+_69048730 Show fit	7.86	ENSRNOT00000086082 ENSRNOT00000078128	Rab11fip1 NCBI RGD Ensembl Show fit	RAB11 family interacting protein 1
chr6_-_140418831 Show fit	7.86	ENSRNOT00000086301	AABR07065768.2 NCBI RGD Ensembl Show fit
chr14_+_84306466 Show fit	7.80	ENSRNOT00000006116	Sec14l4 NCBI RGD Ensembl Show fit	SEC14-like lipid binding 4
chr7_-_75597087 Show fit	7.78	ENSRNOT00000080676	Ywhaz NCBI RGD Ensembl Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr6_-_140715174 Show fit	7.71	ENSRNOT00000085345	AABR07065773.1 NCBI RGD Ensembl Show fit
chr4_-_115157263 Show fit	7.67	ENSRNOT00000015296	Tet3 NCBI RGD Ensembl Show fit	tet methylcytosine dioxygenase 3
chr15_+_30612409 Show fit	7.60	ENSRNOT00000072977	AABR07017748.1 NCBI RGD Ensembl Show fit
chr20_+_5441876 Show fit	7.56	ENSRNOT00000092476	Rps18 NCBI RGD Ensembl Show fit	ribosomal protein S18
chr16_-_41234095 Show fit	7.56	ENSRNOT00000000120	Aga NCBI RGD Ensembl Show fit	aspartylglucosaminidase
chr8_-_122841477 Show fit	7.56	ENSRNOT00000014861	Cmtm7 NCBI RGD Ensembl Show fit	CKLF-like MARVEL transmembrane domain containing 7
chr13_-_52752997 Show fit	7.52	ENSRNOT00000013531	Pkp1 NCBI RGD Ensembl Show fit	plakophilin 1
chr17_+_18029124 Show fit	7.46	ENSRNOT00000022085	Tpmt NCBI RGD Ensembl Show fit	thiopurine S-methyltransferase
chr2_-_34185682 Show fit	7.42	ENSRNOT00000066925 ENSRNOT00000082755	Nln NCBI RGD Ensembl Show fit	neurolysin
chr14_-_46054022 Show fit	7.38	ENSRNOT00000002982	LOC498368 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 0610040J01
chr3_+_20163337 Show fit	7.37	ENSRNOT00000075136	AABR07051726.1 NCBI RGD Ensembl Show fit
chr1_-_101741441 Show fit	7.37	ENSRNOT00000028570	Sult2b1 NCBI RGD Ensembl Show fit	sulfotransferase family 2B member 1
chr2_+_251863069 Show fit	7.33	ENSRNOT00000036282	Syde2 NCBI RGD Ensembl Show fit	synapse defective Rho GTPase homolog 2
chr1_-_32272476 Show fit	7.31	ENSRNOT00000022683	Tert NCBI RGD Ensembl Show fit	telomerase reverse transcriptase
chr17_+_76079907 Show fit	7.30	ENSRNOT00000092710	Proser2 NCBI RGD Ensembl Show fit	proline and serine rich 2
chr14_-_8510138 Show fit	7.25	ENSRNOT00000080758	Arhgap24 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 24
chr5_-_137372524 Show fit	7.22	ENSRNOT00000009061	Tmem125 NCBI RGD Ensembl Show fit	transmembrane protein 125
chr18_+_70427007 Show fit	7.22	ENSRNOT00000087959 ENSRNOT00000019512	Myo5b NCBI RGD Ensembl Show fit	myosin Vb
chr20_-_2210033 Show fit	7.20	ENSRNOT00000084596	Trim26 NCBI RGD Ensembl Show fit	tripartite motif-containing 26

Network of associatons between targets according to the STRING database.

First level regulatory network of Ascl2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
23.2	69.7	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
14.5	43.5	GO:0001905	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
11.6	46.6	GO:0033277	abortive mitotic cell cycle(GO:0033277)
8.5	50.7	GO:0010957	negative regulation of vitamin D biosynthetic process(GO:0010957)
5.6	22.3	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) regulation of exo-alpha-sialidase activity(GO:1903015)
5.4	10.8	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
5.1	15.3	GO:1904457	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) positive regulation of neuronal action potential(GO:1904457)
5.1	20.3	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
4.7	14.0	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
4.5	36.0	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
4.4	13.3	GO:0034635	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
4.4	13.3	GO:0002277	myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585)
4.4	21.8	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
4.1	12.3	GO:0002731	negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
4.0	12.0	GO:0060061	Spemann organizer formation(GO:0060061)
4.0	16.0	GO:0070839	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
3.9	11.8	GO:2000705	regulation of dense core granule biogenesis(GO:2000705)
3.6	10.9	GO:0019265	glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) oxalic acid secretion(GO:0046724)
3.6	21.6	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
3.6	24.9	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
3.5	24.6	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
3.2	9.7	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
3.2	34.8	GO:0015747	urate transport(GO:0015747)
3.1	9.3	GO:0042938	dipeptide transport(GO:0042938)
3.1	18.5	GO:0006287	base-excision repair, gap-filling(GO:0006287)
3.0	11.8	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
2.9	8.6	GO:0042891	antibiotic transport(GO:0042891)
2.8	14.0	GO:0050925	negative regulation of negative chemotaxis(GO:0050925)
2.8	13.9	GO:0061144	alveolar secondary septum development(GO:0061144)
2.6	31.1	GO:1902993	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
2.5	10.0	GO:0070650	actin filament bundle distribution(GO:0070650)
2.5	7.4	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
2.4	12.2	GO:0061743	motor learning(GO:0061743)
2.4	7.3	GO:1900368	regulation of RNA interference(GO:1900368)
2.4	9.7	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
2.4	7.2	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
2.4	7.2	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968) regulation of establishment of blood-brain barrier(GO:0090210)
2.4	4.7	GO:0072021	ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
2.2	17.8	GO:0016584	nucleosome positioning(GO:0016584)
2.2	15.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
2.1	8.5	GO:0042126	nitrate metabolic process(GO:0042126)
2.1	25.1	GO:0010578	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
2.0	12.3	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
2.0	6.1	GO:0060931	sinoatrial node cell development(GO:0060931) His-Purkinje system cell differentiation(GO:0060932)
2.0	6.0	GO:0021577	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
2.0	49.0	GO:0061436	establishment of skin barrier(GO:0061436)
1.9	5.8	GO:1901423	response to benzene(GO:1901423)
1.9	7.7	GO:0044725	chromatin reprogramming in the zygote(GO:0044725)
1.9	7.6	GO:0002337	B-1a B cell differentiation(GO:0002337)
1.9	9.4	GO:0015755	fructose transport(GO:0015755) cellular response to fructose stimulus(GO:0071332)
1.8	12.8	GO:0018879	biphenyl metabolic process(GO:0018879)
1.8	14.6	GO:1990034	calcium ion export from cell(GO:1990034)
1.8	5.4	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
1.8	12.6	GO:0051256	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
1.8	10.8	GO:2000334	blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
1.8	9.0	GO:0015889	cobalamin transport(GO:0015889)
1.8	62.9	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
1.8	7.2	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
1.8	8.9	GO:0000066	mitochondrial ornithine transport(GO:0000066)
1.8	5.4	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
1.7	22.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.7	5.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.7	10.2	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
1.7	5.1	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
1.6	18.1	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
1.6	4.9	GO:0010424	DNA methylation on cytosine within a CG sequence(GO:0010424)
1.6	25.8	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
1.6	7.9	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
1.6	4.7	GO:0018094	protein polyglycylation(GO:0018094)
1.6	7.8	GO:0090168	Golgi reassembly(GO:0090168)
1.5	6.1	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
1.5	6.1	GO:1905231	carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
1.5	9.0	GO:0002326	B cell lineage commitment(GO:0002326)
1.5	10.3	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
1.5	14.7	GO:0070995	NADPH oxidation(GO:0070995)
1.5	10.3	GO:0010216	maintenance of DNA methylation(GO:0010216)
1.4	4.3	GO:0009826	unidimensional cell growth(GO:0009826) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771)
1.4	10.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
1.4	7.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
1.4	9.9	GO:0090403	positive regulation of arachidonic acid secretion(GO:0090238) oxidative stress-induced premature senescence(GO:0090403)
1.4	5.6	GO:0008078	mesodermal cell migration(GO:0008078)
1.4	8.3	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
1.4	9.7	GO:0043686	co-translational protein modification(GO:0043686)
1.3	5.4	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
1.3	8.0	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
1.3	2.6	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
1.3	6.5	GO:0001582	detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
1.3	16.8	GO:0034063	stress granule assembly(GO:0034063)
1.3	5.2	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
1.3	5.1	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
1.3	8.8	GO:0002315	marginal zone B cell differentiation(GO:0002315)
1.3	7.5	GO:0045110	intermediate filament bundle assembly(GO:0045110)
1.2	3.7	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
1.2	9.9	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.2	7.2	GO:0032439	endosome localization(GO:0032439)
1.2	22.5	GO:0048368	lateral mesoderm development(GO:0048368)
1.2	5.9	GO:0010360	negative regulation of anion channel activity(GO:0010360)
1.2	7.0	GO:0019372	lipoxygenase pathway(GO:0019372)
1.1	18.0	GO:0043312	neutrophil degranulation(GO:0043312)
1.1	3.3	GO:0071899	odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
1.1	6.7	GO:0070827	chromatin maintenance(GO:0070827)
1.1	6.6	GO:0045329	carnitine biosynthetic process(GO:0045329)
1.1	23.8	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
1.1	7.4	GO:0000103	sulfate assimilation(GO:0000103)
1.0	6.2	GO:0090367	negative regulation of mRNA modification(GO:0090367)
1.0	5.1	GO:0050917	sensory perception of umami taste(GO:0050917)
1.0	3.0	GO:0060697	glucosylceramide catabolic process(GO:0006680) positive regulation of phospholipid catabolic process(GO:0060697)
1.0	7.9	GO:0035754	B cell chemotaxis(GO:0035754)
1.0	5.0	GO:0033625	positive regulation of integrin activation(GO:0033625)
1.0	7.9	GO:0008228	opsonization(GO:0008228)
1.0	5.8	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.9	4.7	GO:0060174	limb bud formation(GO:0060174)
0.9	12.1	GO:0001977	renal system process involved in regulation of blood volume(GO:0001977)
0.9	8.1	GO:0015867	ADP transport(GO:0015866) ATP transport(GO:0015867)
0.9	2.6	GO:0098749	cerebellar neuron development(GO:0098749)
0.8	13.2	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.8	18.5	GO:0044819	mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.8	4.8	GO:0035426	extracellular matrix-cell signaling(GO:0035426) progesterone secretion(GO:0042701)
0.8	3.1	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.8	3.9	GO:0044691	tooth eruption(GO:0044691)
0.8	2.3	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.8	3.8	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.8	9.9	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.8	5.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.7	2.2	GO:0032497	lipopolysaccharide transport(GO:0015920) detection of lipopolysaccharide(GO:0032497)
0.7	3.7	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.7	7.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.7	3.6	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.7	2.2	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.7	2.1	GO:0071529	cementum mineralization(GO:0071529)
0.7	5.0	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.7	10.6	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.7	6.3	GO:0003373	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.7	2.1	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.7	12.3	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.7	2.0	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.6	3.2	GO:1904717	regulation of AMPA glutamate receptor clustering(GO:1904717)
0.6	3.9	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.6	1.9	GO:0002780	antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.6	1.9	GO:2000853	positive regulation of Schwann cell proliferation(GO:0010625) negative regulation of corticosterone secretion(GO:2000853)
0.6	17.1	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.6	8.9	GO:2000810	regulation of bicellular tight junction assembly(GO:2000810)
0.6	10.4	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.6	5.3	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.6	2.8	GO:0035063	nuclear speck organization(GO:0035063)
0.6	7.9	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.6	2.2	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.6	5.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.5	2.7	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.5	5.4	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.5	6.9	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.5	18.3	GO:0043303	mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.5	1.9	GO:0034760	negative regulation of iron ion transmembrane transport(GO:0034760)
0.5	17.2	GO:0071361	cellular response to ethanol(GO:0071361)
0.5	2.4	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.5	1.4	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.4	27.4	GO:0032094	response to food(GO:0032094)
0.4	11.4	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4	0.9	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.4	4.2	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.4	5.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.4	0.8	GO:1903969	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.4	4.8	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.4	5.6	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.4	1.5	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.4	1.5	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.4	6.1	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4	10.8	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.4	1.1	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.3	2.4	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.3	5.1	GO:0006517	protein deglycosylation(GO:0006517)
0.3	0.7	GO:0097187	dentinogenesis(GO:0097187)
0.3	3.6	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.3	1.9	GO:0071409	cellular response to cycloheximide(GO:0071409)
0.3	2.9	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.3	2.4	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.3	1.2	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3	13.7	GO:0006956	complement activation(GO:0006956)
0.3	13.7	GO:0045773	positive regulation of axon extension(GO:0045773)
0.3	11.4	GO:0070265	necrotic cell death(GO:0070265)
0.3	7.4	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.3	9.7	GO:1901998	toxin transport(GO:1901998)
0.3	2.8	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.3	11.2	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.3	0.8	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.3	3.8	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3	3.5	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3	2.7	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.3	2.9	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.3	3.4	GO:0007379	segment specification(GO:0007379)
0.3	3.9	GO:0035855	megakaryocyte development(GO:0035855)
0.2	2.5	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.2	13.2	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2	6.5	GO:0006829	zinc II ion transport(GO:0006829)
0.2	21.0	GO:0008203	cholesterol metabolic process(GO:0008203)
0.2	2.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.2	6.7	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.2	5.4	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.2	11.2	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2	1.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.2	8.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.2	2.1	GO:2000811	negative regulation of anoikis(GO:2000811)
0.2	4.8	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.2	1.6	GO:0060056	mammary gland involution(GO:0060056)
0.2	5.7	GO:0018345	protein palmitoylation(GO:0018345)
0.2	0.5	GO:0015942	formate metabolic process(GO:0015942)
0.2	2.5	GO:0032060	bleb assembly(GO:0032060)
0.2	2.1	GO:2000696	regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.2	0.8	GO:0071955	recycling endosome to Golgi transport(GO:0071955)
0.2	0.5	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.7	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1	1.4	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.1	9.0	GO:0043488	regulation of mRNA stability(GO:0043488)
0.1	2.1	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.1	7.3	GO:0033045	regulation of sister chromatid segregation(GO:0033045)
0.1	0.7	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	7.1	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.1	0.5	GO:0071494	cellular response to UV-C(GO:0071494)
0.1	2.8	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.1	2.3	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1	5.2	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.1	6.5	GO:0045454	cell redox homeostasis(GO:0045454)
0.1	2.2	GO:0032757	positive regulation of interleukin-8 production(GO:0032757)
0.1	2.6	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.7	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.1	1.5	GO:0045109	intermediate filament organization(GO:0045109)
0.1	0.6	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1	2.9	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.1	3.2	GO:0034605	cellular response to heat(GO:0034605)
0.1	4.8	GO:0007093	mitotic cell cycle checkpoint(GO:0007093)
0.1	12.6	GO:0043413	protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.1	1.6	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1	2.0	GO:0042073	intraciliary transport(GO:0042073)
0.1	1.7	GO:0097352	autophagosome maturation(GO:0097352)
0.1	3.6	GO:0032024	positive regulation of insulin secretion(GO:0032024)
0.1	2.7	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	0.3	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1	0.5	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.1	0.2	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.1	2.8	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1	0.9	GO:0051597	response to methylmercury(GO:0051597)
0.0	1.0	GO:0051642	centrosome localization(GO:0051642)
0.0	2.1	GO:0030148	sphingolipid biosynthetic process(GO:0030148)
0.0	2.0	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	2.3	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	4.4	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0	1.1	GO:0006953	acute-phase response(GO:0006953)
0.0	2.0	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	1.7	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.8	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	5.1	GO:0032259	methylation(GO:0032259)
0.0	0.5	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	1.4	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	1.8	GO:0006401	RNA catabolic process(GO:0006401)
0.0	1.0	GO:0009791	post-embryonic development(GO:0009791)
0.0	2.3	GO:0006869	lipid transport(GO:0006869)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.5	22.5	GO:0071149	TEAD-2-YAP complex(GO:0071149)
7.3	21.8	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
6.0	17.9	GO:0005760	gamma DNA polymerase complex(GO:0005760)
5.8	46.6	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
3.7	69.7	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
2.7	13.3	GO:0097169	NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
2.6	62.9	GO:0016327	apicolateral plasma membrane(GO:0016327)
2.5	17.6	GO:0097524	sperm plasma membrane(GO:0097524)
2.4	17.0	GO:0005579	membrane attack complex(GO:0005579)
2.4	11.9	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
2.3	18.4	GO:0070820	cytolytic granule(GO:0044194) tertiary granule(GO:0070820)
2.1	8.3	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
2.0	21.7	GO:1990635	proximal dendrite(GO:1990635)
2.0	7.9	GO:0097149	centralspindlin complex(GO:0097149)
1.5	4.6	GO:1990423	RZZ complex(GO:1990423)
1.5	21.1	GO:0044232	organelle membrane contact site(GO:0044232)
1.4	103.2	GO:0045095	keratin filament(GO:0045095)
1.4	8.1	GO:0071817	MMXD complex(GO:0071817)
1.3	6.5	GO:1903767	sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
1.2	15.2	GO:0032591	dendritic spine membrane(GO:0032591)
1.1	3.3	GO:1990907	beta-catenin-TCF complex(GO:1990907)
1.1	30.0	GO:0000788	nuclear nucleosome(GO:0000788)
1.0	8.2	GO:0016589	NURF complex(GO:0016589)
1.0	7.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
1.0	9.1	GO:0045179	apical cortex(GO:0045179)
1.0	3.9	GO:0002947	tumor necrosis factor receptor superfamily complex(GO:0002947)
1.0	3.8	GO:0070436	Grb2-EGFR complex(GO:0070436)
1.0	13.3	GO:0032426	stereocilium tip(GO:0032426)
0.9	26.1	GO:0042629	mast cell granule(GO:0042629)
0.9	14.7	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.9	7.7	GO:0001940	male pronucleus(GO:0001940)
0.8	7.6	GO:0032437	cuticular plate(GO:0032437)
0.8	9.0	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.7	3.3	GO:0045098	type III intermediate filament(GO:0045098)
0.6	19.1	GO:0099738	cell cortex region(GO:0099738)
0.6	11.7	GO:0030057	desmosome(GO:0030057)
0.6	4.3	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.6	72.5	GO:0072562	blood microparticle(GO:0072562)
0.6	6.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.6	2.2	GO:0031528	microvillus membrane(GO:0031528)
0.5	5.4	GO:0070187	telosome(GO:0070187)
0.5	6.0	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.5	6.5	GO:0008385	IkappaB kinase complex(GO:0008385)
0.5	6.8	GO:0042581	specific granule(GO:0042581)
0.5	44.4	GO:0030863	cortical cytoskeleton(GO:0030863)
0.5	9.1	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.5	5.3	GO:0042555	MCM complex(GO:0042555)
0.5	36.5	GO:0031526	brush border membrane(GO:0031526)
0.4	3.9	GO:0031209	SCAR complex(GO:0031209)
0.4	2.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.4	32.2	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.4	24.1	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.4	35.2	GO:0017053	transcriptional repressor complex(GO:0017053)
0.4	7.9	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.4	16.8	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.4	2.1	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.3	6.7	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.3	6.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.3	2.8	GO:0005610	laminin-5 complex(GO:0005610)
0.3	6.1	GO:0005614	interstitial matrix(GO:0005614)
0.3	0.9	GO:0032173	septin collar(GO:0032173)
0.3	12.6	GO:0045171	intercellular bridge(GO:0045171)
0.3	0.8	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.3	6.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.3	107.0	GO:0045177	apical part of cell(GO:0045177)
0.3	2.4	GO:0044292	dendrite terminus(GO:0044292)
0.3	6.8	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.3	10.3	GO:0000791	euchromatin(GO:0000791)
0.2	1.2	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.2	6.9	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.2	3.7	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2	26.9	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2	3.0	GO:0031616	spindle pole centrosome(GO:0031616)
0.2	14.5	GO:0005811	lipid particle(GO:0005811)
0.2	19.2	GO:0005923	bicellular tight junction(GO:0005923)
0.2	1.6	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2	2.0	GO:0044613	nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.2	1.8	GO:0000178	exosome (RNase complex)(GO:0000178)
0.2	4.4	GO:1902711	GABA-A receptor complex(GO:1902711)
0.2	16.8	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.2	14.5	GO:0034399	nuclear periphery(GO:0034399)
0.2	2.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	3.4	GO:0000421	autophagosome membrane(GO:0000421)
0.2	8.4	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	3.8	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	3.8	GO:0044295	axonal growth cone(GO:0044295)
0.1	1.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	11.0	GO:0030496	midbody(GO:0030496)
0.1	44.4	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1	38.0	GO:0016607	nuclear speck(GO:0016607)
0.1	7.6	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	0.9	GO:0043596	nuclear replication fork(GO:0043596)
0.1	5.6	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.1	25.5	GO:0000790	nuclear chromatin(GO:0000790)
0.1	8.6	GO:0005795	Golgi stack(GO:0005795)
0.1	2.0	GO:0030992	intraciliary transport particle B(GO:0030992)
0.1	1.7	GO:0032420	stereocilium(GO:0032420)
0.1	5.2	GO:0016605	PML body(GO:0016605)
0.1	7.3	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	1.1	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.1	4.7	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1	5.8	GO:0044798	nuclear transcription factor complex(GO:0044798)
0.1	14.2	GO:0005925	focal adhesion(GO:0005925)
0.0	0.8	GO:0097546	ciliary base(GO:0097546)
0.0	0.7	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.2	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.2	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	4.3	GO:0001650	fibrillar center(GO:0001650)
0.0	0.8	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	3.3	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	2.5	GO:0005814	centriole(GO:0005814)
0.0	1.4	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	1.1	GO:0035770	ribonucleoprotein granule(GO:0035770)
0.0	1.3	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	1.5	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.6	GO:0036064	ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.8	26.5	GO:0031714	C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
7.7	76.9	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
6.1	18.4	GO:0030348	syntaxin-3 binding(GO:0030348)
5.2	46.6	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
4.8	14.3	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
4.0	12.1	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
4.0	11.9	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
3.8	15.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
3.7	22.1	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
3.6	10.8	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
3.3	13.3	GO:0045159	myosin II binding(GO:0045159)
3.0	36.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
3.0	17.9	GO:0042289	MHC class II protein binding(GO:0042289)
2.9	8.6	GO:0042895	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) antibiotic transporter activity(GO:0042895)
2.8	25.5	GO:0019534	toxin transporter activity(GO:0019534)
2.6	10.3	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
2.6	10.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
2.5	22.3	GO:0046790	virion binding(GO:0046790)
2.5	7.4	GO:0070012	oligopeptidase activity(GO:0070012)
2.5	7.4	GO:0050294	steroid sulfotransferase activity(GO:0050294)
2.4	7.2	GO:0000703	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
2.4	7.2	GO:0097603	temperature-gated ion channel activity(GO:0097603)
2.3	18.7	GO:0070053	thrombospondin receptor activity(GO:0070053)
2.3	32.2	GO:0042043	neurexin family protein binding(GO:0042043)
2.3	9.0	GO:0070644	vitamin D response element binding(GO:0070644)
2.2	6.7	GO:0000991	transcription factor activity, core RNA polymerase II binding(GO:0000991)
2.2	10.9	GO:0008453	alanine-glyoxylate transaminase activity(GO:0008453)
2.0	20.3	GO:0019957	C-C chemokine binding(GO:0019957)
1.9	5.8	GO:0016748	succinyltransferase activity(GO:0016748)
1.9	7.7	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
1.9	13.3	GO:0005138	interleukin-6 receptor binding(GO:0005138)
1.8	16.2	GO:0042285	xylosyltransferase activity(GO:0042285)
1.8	16.0	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
1.8	7.0	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
1.7	5.2	GO:0001716	L-amino-acid oxidase activity(GO:0001716)
1.7	13.9	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
1.7	5.2	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
1.7	15.4	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
1.6	6.5	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
1.6	9.7	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.6	9.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
1.6	4.7	GO:0070735	protein-glycine ligase activity(GO:0070735)
1.4	5.6	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.4	6.9	GO:0032564	dATP binding(GO:0032564)
1.4	6.8	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
1.3	5.3	GO:0061665	SUMO ligase activity(GO:0061665)
1.3	9.3	GO:0004064	arylesterase activity(GO:0004064)
1.3	10.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.2	3.7	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
1.2	7.5	GO:0008172	S-methyltransferase activity(GO:0008172)
1.2	24.9	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.2	14.7	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.2	9.7	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273) NFAT protein binding(GO:0051525)
1.2	8.5	GO:0043546	molybdopterin cofactor binding(GO:0043546)
1.2	4.8	GO:0019002	GMP binding(GO:0019002)
1.2	8.3	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
1.2	14.0	GO:0008046	axon guidance receptor activity(GO:0008046)
1.2	2.3	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
1.1	22.5	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
1.1	9.0	GO:0031419	cobalamin binding(GO:0031419)
1.1	8.9	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
1.0	9.4	GO:0070061	fructose binding(GO:0070061)
1.0	6.1	GO:0045545	syndecan binding(GO:0045545)
1.0	14.3	GO:0043522	leucine zipper domain binding(GO:0043522)
1.0	3.0	GO:0070976	TIR domain binding(GO:0070976)
1.0	5.9	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
1.0	2.9	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.9	8.1	GO:0005347	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.9	2.7	GO:0038100	nodal binding(GO:0038100)
0.9	19.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.9	2.6	GO:0008948	oxaloacetate decarboxylase activity(GO:0008948) hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.8	15.0	GO:0003993	acid phosphatase activity(GO:0003993)
0.8	12.6	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.8	3.8	GO:0035184	histone threonine kinase activity(GO:0035184)
0.7	166.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.7	2.2	GO:0070506	high-density lipoprotein particle receptor activity(GO:0070506)
0.7	9.6	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.7	3.7	GO:0004586	ornithine decarboxylase activity(GO:0004586)
0.7	13.6	GO:0015643	toxic substance binding(GO:0015643)
0.7	4.9	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.7	9.7	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.7	5.4	GO:0030274	LIM domain binding(GO:0030274)
0.7	2.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.7	41.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.7	25.1	GO:0043236	laminin binding(GO:0043236)
0.7	6.6	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.6	5.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.6	7.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.6	19.0	GO:0034061	DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.6	16.2	GO:0070064	proline-rich region binding(GO:0070064)
0.6	2.3	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6	12.7	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.6	5.1	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.6	7.9	GO:0017154	semaphorin receptor activity(GO:0017154)
0.6	12.3	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.5	3.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.5	16.6	GO:0001540	beta-amyloid binding(GO:0001540)
0.5	18.5	GO:0004180	carboxypeptidase activity(GO:0004180)
0.5	16.4	GO:0042169	SH2 domain binding(GO:0042169)
0.5	6.0	GO:0051787	misfolded protein binding(GO:0051787)
0.4	6.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.4	6.2	GO:0008143	poly(A) binding(GO:0008143)
0.4	2.1	GO:0001729	ceramide kinase activity(GO:0001729)
0.4	14.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.4	57.6	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4	10.8	GO:0005540	hyaluronic acid binding(GO:0005540)
0.4	1.9	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.4	3.7	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.4	8.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.4	1.1	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.4	1.4	GO:0004452	isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.4	7.5	GO:0005521	lamin binding(GO:0005521)
0.3	3.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.3	5.4	GO:0070182	DNA polymerase binding(GO:0070182)
0.3	2.4	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.3	1.7	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.3	2.5	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.3	9.9	GO:0004623	phospholipase A2 activity(GO:0004623)
0.3	9.8	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3	7.9	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.3	6.6	GO:0004383	guanylate cyclase activity(GO:0004383)
0.3	0.8	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.3	0.8	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3	2.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.2	3.6	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.2	1.2	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.2	5.4	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2	5.4	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
0.2	6.3	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.2	3.2	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.2	2.9	GO:0003688	DNA replication origin binding(GO:0003688)
0.2	4.7	GO:0071837	HMG box domain binding(GO:0071837)
0.2	1.8	GO:0070700	BMP receptor binding(GO:0070700)
0.2	14.0	GO:0003725	double-stranded RNA binding(GO:0003725)
0.2	3.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.2	10.6	GO:0004004	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2	6.7	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.2	20.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.2	5.7	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2	20.9	GO:0017124	SH3 domain binding(GO:0017124)
0.2	4.4	GO:0004890	GABA-A receptor activity(GO:0004890)
0.2	6.6	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.2	10.4	GO:0033613	activating transcription factor binding(GO:0033613)
0.2	2.8	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.2	9.0	GO:0004386	helicase activity(GO:0004386)
0.1	0.7	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1	2.4	GO:0002162	dystroglycan binding(GO:0002162)
0.1	9.4	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.1	4.4	GO:0030332	cyclin binding(GO:0030332)
0.1	3.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	4.8	GO:0070063	RNA polymerase binding(GO:0070063)
0.1	40.6	GO:0045296	cadherin binding(GO:0045296)
0.1	3.4	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.1	0.9	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	2.1	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	6.4	GO:0019843	rRNA binding(GO:0019843)
0.1	0.5	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	5.4	GO:0046332	SMAD binding(GO:0046332)
0.1	0.5	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1	2.0	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.1	1.6	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	7.9	GO:0030165	PDZ domain binding(GO:0030165)
0.1	4.9	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.1	6.3	GO:0008565	protein transporter activity(GO:0008565)
0.1	2.4	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.1	1.5	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	3.7	GO:0002039	p53 binding(GO:0002039)
0.1	1.0	GO:0001972	retinoic acid binding(GO:0001972)
0.1	2.7	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1	0.3	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	4.6	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	4.5	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.0	5.5	GO:0005506	iron ion binding(GO:0005506)
0.0	3.3	GO:0005254	chloride channel activity(GO:0005254)
0.0	3.9	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	2.0	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	6.8	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.5	GO:0045125	bioactive lipid receptor activity(GO:0045125)
0.0	4.5	GO:0008168	methyltransferase activity(GO:0008168)
0.0	0.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	3.2	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.0	3.5	GO:0008233	peptidase activity(GO:0008233)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	29.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
1.6	17.6	ST JAK STAT PATHWAY	Jak-STAT Pathway
1.5	10.3	PID IL5 PATHWAY	IL5-mediated signaling events
1.3	91.8	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
1.1	10.8	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.8	15.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.7	9.7	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.6	9.7	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.6	28.1	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.6	7.8	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.6	2.9	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.5	13.5	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.5	9.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.5	16.8	PID EPHB FWD PATHWAY	EPHB forward signaling
0.5	4.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.5	13.3	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.5	14.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.5	18.7	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.4	6.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.4	15.5	PID BCR 5PATHWAY	BCR signaling pathway
0.4	25.1	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.4	7.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.4	7.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4	17.2	PID FGF PATHWAY	FGF signaling pathway
0.4	81.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3	12.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.3	9.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.3	8.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.3	15.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.3	11.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.3	15.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.3	4.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.2	5.9	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.2	13.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.2	12.0	PID E2F PATHWAY	E2F transcription factor network
0.2	6.5	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.2	11.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.2	11.4	PID CMYB PATHWAY	C-MYB transcription factor network
0.2	5.2	PID ATR PATHWAY	ATR signaling pathway
0.2	31.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2	6.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.2	7.9	PID PLK1 PATHWAY	PLK1 signaling events
0.2	0.8	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.2	2.9	PID ERBB4 PATHWAY	ErbB4 signaling events
0.2	13.3	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	3.9	PID TNF PATHWAY	TNF receptor signaling pathway
0.1	2.2	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	5.4	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	3.4	PID P73PATHWAY	p73 transcription factor network
0.1	5.2	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	2.3	PID ARF6 PATHWAY	Arf6 signaling events
0.1	1.9	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	4.8	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	0.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	3.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.5	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.8	69.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
5.1	20.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
3.6	58.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
2.2	73.2	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
1.9	26.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
1.6	9.9	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
1.4	23.5	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
1.4	8.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
1.4	14.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
1.3	27.0	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
1.2	34.2	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
1.1	8.6	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
1.1	13.9	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
1.0	9.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
1.0	24.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
1.0	12.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.9	16.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.9	10.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.9	7.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.8	11.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.8	22.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.8	17.5	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.7	7.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.7	12.9	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.7	5.4	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.7	12.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.6	23.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.6	27.6	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.6	9.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.6	8.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.6	7.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.6	10.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.6	7.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.6	1.7	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.6	9.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.6	16.0	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.6	7.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.5	6.0	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.5	22.3	REACTOME AMYLOIDS	Genes involved in Amyloids
0.5	6.0	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.5	5.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.5	11.5	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.5	12.0	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.5	14.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.5	3.9	REACTOME SIGNALLING BY NGF	Genes involved in Signalling by NGF
0.5	8.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.5	11.8	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.5	11.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4	32.0	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.4	3.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.4	5.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.4	5.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3	8.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3	5.8	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.3	22.5	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.3	5.6	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3	8.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.3	7.2	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.3	0.8	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.2	5.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.2	5.8	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.2	2.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.2	2.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	9.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	4.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2	3.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	3.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	12.7	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.2	3.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.2	4.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	4.9	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.2	2.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.2	6.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	10.8	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.1	1.9	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	12.5	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.1	7.4	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	2.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	18.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	2.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	1.4	REACTOME TRANSCRIPTION COUPLED NER TC NER	Genes involved in Transcription-coupled NER (TC-NER)
0.1	1.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	0.9	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	4.3	REACTOME BIOLOGICAL OXIDATIONS	Genes involved in Biological oxidations
0.1	0.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	0.8	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	1.8	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	1.9	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	2.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication

Results for Ascl2

Z-value: 1.17

Motif logo

Transcription factors associated with Ascl2

Activity-expression correlation:

Activity profile of Ascl2 motif

Sorted Z-values of Ascl2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Ascl2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: