ISMARA results: Arid3a

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Arid3a

Z-value: 0.93

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Transcription factors associated with Arid3a

Gene Symbol	Gene ID	Gene Info
Arid3a NCBI RGD Ensembl	ENSRNOG00000026435	AT-rich interaction domain 3A

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Arid3a	rn6_v1_chr7_-_12598183_12598183	-0.38	2.2e-12	Click!

Activity profile of Arid3a motif

Sorted Z-values of Arid3a motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_+_61850348 Show fit	35.86	ENSRNOT00000013423	Akr1b7 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member B7
chr1_+_156552328 Show fit	25.92	ENSRNOT00000055401	Dlg2 NCBI RGD Ensembl Show fit	discs large MAGUK scaffold protein 2
chr10_-_103848035 Show fit	25.79	ENSRNOT00000029001	Fads6 NCBI RGD Ensembl Show fit	fatty acid desaturase 6
chr15_-_110046687 Show fit	22.23	ENSRNOT00000057404 ENSRNOT00000006624 ENSRNOT00000089695	Nalcn NCBI RGD Ensembl Show fit	sodium leak channel, non-selective
chr15_-_60056582 Show fit	19.82	ENSRNOT00000087569 ENSRNOT00000012530	Dnajc15 NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member C15
chrX_+_106774980 Show fit	19.59	ENSRNOT00000046091	Tceal7 NCBI RGD Ensembl Show fit	transcription elongation factor A like 7
chrX_-_40086870 Show fit	15.81	ENSRNOT00000010027	Smpx NCBI RGD Ensembl Show fit	small muscle protein, X-linked
chr2_-_210116038 Show fit	15.50	ENSRNOT00000074950	LOC684509 NCBI RGD Ensembl Show fit	similar to NADH-ubiquinone oxidoreductase B9 subunit (Complex I-B9) (CI-B9)
chr13_-_90641772 Show fit	15.15	ENSRNOT00000064601	Atp1a4 NCBI RGD Ensembl Show fit	ATPase Na+/K+ transporting subunit alpha 4
chr1_-_277181345 Show fit	14.86	ENSRNOT00000038017 ENSRNOT00000038038	Nrap NCBI RGD Ensembl Show fit	nebulin-related anchoring protein

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid3a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	43.3	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	30.6	GO:0055114	oxidation-reduction process(GO:0055114)
2.4	25.9	GO:0046710	GDP metabolic process(GO:0046710)
3.2	22.2	GO:0060075	regulation of resting membrane potential(GO:0060075)
6.6	19.8	GO:1901856	negative regulation of cellular respiration(GO:1901856)
0.2	18.4	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1	15.8	GO:0006941	striated muscle contraction(GO:0006941)
0.9	15.2	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.8	13.6	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.1	12.2	GO:0008637	apoptotic mitochondrial changes(GO:0008637)

Showing 1 to 10 of 86 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	61.2	GO:0005739	mitochondrion(GO:0005739)
0.1	40.2	GO:0005743	mitochondrial inner membrane(GO:0005743)
6.1	30.7	GO:0005927	muscle tendon junction(GO:0005927)
1.6	25.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.3	15.5	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.3	15.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2	12.2	GO:0005811	lipid particle(GO:0005811)
0.2	11.8	GO:0034707	chloride channel complex(GO:0034707)
0.5	11.5	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
3.8	11.3	GO:0044317	rod spherule(GO:0044317)

Showing 1 to 10 of 42 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.6	43.5	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	43.3	GO:0004984	olfactory receptor activity(GO:0004984)
2.6	25.9	GO:0004385	guanylate kinase activity(GO:0004385)
2.8	22.2	GO:0022840	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
1.1	15.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.9	14.9	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.6	13.8	GO:0031489	myosin V binding(GO:0031489)
0.5	13.6	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	13.5	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.1	12.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)

Showing 1 to 10 of 71 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	10.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	9.8	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.2	9.7	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	8.1	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	6.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	5.5	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	5.5	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.2	4.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	3.5	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.4	3.0	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway

Showing 1 to 10 of 16 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	28.8	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.4	17.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.4	11.0	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.4	8.7	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.4	8.4	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.8	8.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.2	6.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	6.1	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.4	5.9	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	4.1	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation

Showing 1 to 10 of 22 entries

Results for Arid3a

Z-value: 0.93

Motif logo

Transcription factors associated with Arid3a

Activity-expression correlation:

Activity profile of Arid3a motif

Sorted Z-values of Arid3a motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid3a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: