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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Arid3a

Z-value: 0.93

Motif logo

Transcription factors associated with Arid3a

Gene Symbol Gene ID Gene Info
ENSRNOG00000026435 AT-rich interaction domain 3A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Arid3arn6_v1_chr7_-_12598183_12598183-0.382.2e-12Click!

Activity profile of Arid3a motif

Sorted Z-values of Arid3a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_61850348 35.86 ENSRNOT00000013423
aldo-keto reductase family 1, member B7
chr1_+_156552328 25.92 ENSRNOT00000055401
discs large MAGUK scaffold protein 2
chr10_-_103848035 25.79 ENSRNOT00000029001
fatty acid desaturase 6
chr15_-_110046687 22.23 ENSRNOT00000057404
ENSRNOT00000006624
ENSRNOT00000089695
sodium leak channel, non-selective
chr15_-_60056582 19.82 ENSRNOT00000087569
ENSRNOT00000012530
DnaJ heat shock protein family (Hsp40) member C15
chrX_+_106774980 19.59 ENSRNOT00000046091
transcription elongation factor A like 7
chrX_-_40086870 15.81 ENSRNOT00000010027
small muscle protein, X-linked
chr2_-_210116038 15.50 ENSRNOT00000074950
similar to NADH-ubiquinone oxidoreductase B9 subunit (Complex I-B9) (CI-B9)
chr13_-_90641772 15.15 ENSRNOT00000064601
ATPase Na+/K+ transporting subunit alpha 4
chr1_-_277181345 14.86 ENSRNOT00000038017
ENSRNOT00000038038
nebulin-related anchoring protein
chr1_+_70253650 14.05 ENSRNOT00000087668
zinc finger, imprinted 1
chr2_-_41784929 13.82 ENSRNOT00000086851
RAB3C, member RAS oncogene family
chr5_-_128333805 13.59 ENSRNOT00000037523
zinc finger FYVE-type containing 9
chr5_+_90338795 12.85 ENSRNOT00000077864
ENSRNOT00000058882
similar to RIKEN cDNA 2310003M01
chr20_+_31339787 12.22 ENSRNOT00000082463
apoptosis inducing factor, mitochondria associated 2
chr1_-_82409639 11.63 ENSRNOT00000031326
glutamate-rich 4
chr5_+_2353468 11.48 ENSRNOT00000090346
staufen double-stranded RNA binding protein 2
chr5_+_165465095 11.47 ENSRNOT00000031978
hypothetical protein LOC691354
chr4_-_16669368 11.29 ENSRNOT00000007608
piccolo (presynaptic cytomatrix protein)
chr4_+_30313102 11.24 ENSRNOT00000012657
ankyrin repeat and SOCS box-containing 4
chr6_-_108120579 10.83 ENSRNOT00000041163
ectonucleoside triphosphate diphosphohydrolase 5
chr16_+_29674793 10.53 ENSRNOT00000059724
annexin A10
chr11_-_72109964 9.93 ENSRNOT00000058917

chrX_-_64726210 9.72 ENSRNOT00000076012
ENSRNOT00000086265
ankyrin repeat and SOCS box-containing 12
chr16_-_14382641 8.95 ENSRNOT00000018723
growth hormone inducible transmembrane protein
chr2_-_197878142 8.70 ENSRNOT00000087052
threonyl-tRNA synthetase 2, mitochondrial (putative)
chr14_+_39964588 8.68 ENSRNOT00000003240
gamma-aminobutyric acid type A receptor gamma 1 subunit
chr5_+_120340646 8.42 ENSRNOT00000086259
ENSRNOT00000086539
DnaJ heat shock protein family (Hsp40) member C6
chr5_+_162183327 8.34 ENSRNOT00000037875
PRAME family member 8
chr2_+_198303168 8.31 ENSRNOT00000056262
myotubularin related protein 11
chr10_+_97771264 8.28 ENSRNOT00000005257
arylsulfatase G
chr9_-_15646846 7.85 ENSRNOT00000087971
mitochondrial ribosomal protein S10
chr4_-_98305173 7.79 ENSRNOT00000010151
interleukin 23 receptor
chr8_-_109621408 7.72 ENSRNOT00000087398
protein phosphatase 2, regulatory subunit B'', alpha
chr14_+_7949239 7.71 ENSRNOT00000044617
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4-like 1
chr10_+_65272849 7.52 ENSRNOT00000014386
Era-like 12S mitochondrial rRNA chaperone 1
chr13_+_89243336 7.19 ENSRNOT00000085688

chr3_+_48096954 7.10 ENSRNOT00000068238
ENSRNOT00000064344
ENSRNOT00000044638
solute carrier family 4 member 10
chr8_+_70708873 6.47 ENSRNOT00000045106
poly (ADP-ribose) polymerase family, member 16
chr11_+_20474483 6.39 ENSRNOT00000082417
ENSRNOT00000002895
neural cell adhesion molecule 2
chr8_+_130350510 6.38 ENSRNOT00000073376
SS18 like 2
chr11_-_4332255 6.32 ENSRNOT00000087133
cell adhesion molecule 2
chr8_+_70760922 6.23 ENSRNOT00000044887
cartilage intermediate layer protein
chr1_+_225068009 6.16 ENSRNOT00000026651
UBX domain protein 1
chr18_+_16146447 6.11 ENSRNOT00000022117
polypeptide N-acetylgalactosaminyltransferase 1
chr17_-_69404323 6.00 ENSRNOT00000051342
ENSRNOT00000066282
aldo-keto reductase family 1, member C2
chr7_-_12432130 5.87 ENSRNOT00000077301
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr14_+_17210733 5.47 ENSRNOT00000003075
C-X-C motif chemokine ligand 10
chr12_-_29919320 5.42 ENSRNOT00000038092
tRNA-yW synthesizing protein 1 homolog
chr12_-_38916237 5.18 ENSRNOT00000074517
transmembrane protein 120B
chr16_-_69176036 4.50 ENSRNOT00000018369
proline synthetase co-transcribed homolog (bacterial)
chr9_-_86103158 4.35 ENSRNOT00000021528
cullin 3
chrX_-_31013030 4.31 ENSRNOT00000004451

chr4_-_161658519 4.21 ENSRNOT00000007634
ENSRNOT00000067895
tubby-like protein 3
chr2_+_149843282 4.14 ENSRNOT00000074805
similar to hypothetical protein C130079G13
chr7_+_44009069 4.06 ENSRNOT00000005523
MGAT4 family, member C
chr5_+_36566783 4.05 ENSRNOT00000077650
F-box and leucine-rich repeat protein 4
chr11_-_71135493 3.91 ENSRNOT00000050535
forty-two-three domain containing 1
chr12_+_46869836 3.91 ENSRNOT00000084421
sirtuin 4
chr4_-_161850875 3.88 ENSRNOT00000009467
pregnancy-zone protein
chr3_-_102432479 3.82 ENSRNOT00000047270
olfactory receptor 747
chr6_-_103616342 3.81 ENSRNOT00000008621
similar to Macrophage migration inhibitory factor (MIF) (Delayed early response protein 6)
chr8_+_70952203 3.78 ENSRNOT00000019671
mitochondrial methionyl-tRNA formyltransferase
chr13_-_34251942 3.50 ENSRNOT00000044095
translin
chr1_+_116604550 3.46 ENSRNOT00000083587
ubiquitin protein ligase E3A
chr17_+_54181419 3.39 ENSRNOT00000023861
kinesin family member 5B
chr9_-_65442257 3.28 ENSRNOT00000037660
family with sequence similarity 126, member B
chr1_+_204959174 3.24 ENSRNOT00000023257
zinc finger RANBP2-type containing 1
chr7_+_14865941 3.18 ENSRNOT00000066654
cytochrome P450, family 4, subfamily f, polypeptide 40
chr6_+_99444013 3.17 ENSRNOT00000058642
protein phosphatase 1, regulatory subunit 36
chr14_-_21909646 3.17 ENSRNOT00000088024
casein alpha s2-like B
chr15_-_6587367 3.16 ENSRNOT00000038449
zinc finger protein 385D
chr1_+_51619875 3.14 ENSRNOT00000023319
poly(A) binding protein, cytoplasmic 6
chr16_-_50358809 3.11 ENSRNOT00000039331
melatonin receptor 1A
chr11_-_43099412 3.08 ENSRNOT00000002281
gamma-aminobutyric acid type A receptor rho3 subunit
chr1_+_99398248 3.04 ENSRNOT00000072699

chr8_-_116993193 3.00 ENSRNOT00000026327
dystroglycan 1
chr15_+_10120206 2.96 ENSRNOT00000033048
retinoic acid receptor, beta
chr14_+_85871597 2.95 ENSRNOT00000079671
ankyrin repeat domain 36
chr2_+_147496229 2.94 ENSRNOT00000022105
transmembrane 4 L six family member 4
chr3_-_63211842 2.93 ENSRNOT00000008371
ENSRNOT00000050355
phosphodiesterase 11A
chr6_-_136436818 2.87 ENSRNOT00000082600
protein phosphatase 1, regulatory subunit 13B
chr3_-_73636542 2.86 ENSRNOT00000074870
olfactory receptor 8K3-like
chr3_-_145810834 2.85 ENSRNOT00000075429
zinc finger protein 120-like
chr3_-_102773801 2.72 ENSRNOT00000047051
olfactory receptor 767
chr3_-_173371835 2.70 ENSRNOT00000073650
zinc finger protein 709-like
chr2_-_154508877 2.68 ENSRNOT00000086472
similar to hypothetical protein E130311K13
chr3_-_74749960 2.59 ENSRNOT00000046197
olfactory receptor 491
chr20_-_43932361 2.51 ENSRNOT00000091030
ret finger protein-like 4B
chr1_-_170916059 2.49 ENSRNOT00000041974
olfactory receptor 217
chr8_-_18408179 2.41 ENSRNOT00000040032

chr7_-_9104719 2.41 ENSRNOT00000088247
olfactory receptor 6C74-like
chr2_-_155381839 2.37 ENSRNOT00000057657
vomeronasal 2 receptor, 47
chr3_-_21904133 2.34 ENSRNOT00000090576
ENSRNOT00000087611
ENSRNOT00000066377
spermatid perinuclear RNA binding protein
chr1_-_248898607 2.32 ENSRNOT00000074393
dickkopf WNT signaling pathway inhibitor 1
chr13_+_50873605 2.28 ENSRNOT00000004382
fibromodulin
chr2_+_27630285 2.22 ENSRNOT00000032960
ankyrin repeat domain 31
chr16_-_75499012 2.17 ENSRNOT00000058039
defensin alpha 10
chr9_+_111597037 2.13 ENSRNOT00000021758
FER tyrosine kinase
chr19_+_22699808 2.12 ENSRNOT00000023169
similar to RIKEN cDNA 4921524J17
chr1_+_127604197 2.09 ENSRNOT00000018463
lines homolog 1
chr11_+_84827062 2.08 ENSRNOT00000058006
RIKEN cDNA A930003A15 gene
chr12_+_48677905 2.07 ENSRNOT00000083196
RIKEN cDNA 1700069L16 gene
chr2_+_46186105 2.05 ENSRNOT00000071256
olfactory receptor 145-like
chr5_-_126323799 2.01 ENSRNOT00000089934
maestro heat-like repeat family member 7
chr9_+_42945358 2.00 ENSRNOT00000059806
fer-1-like family member 5
chr3_-_76256129 1.98 ENSRNOT00000072741
olfactory receptor 5D14-like
chr5_-_4975436 1.97 ENSRNOT00000062006
XK related 9
chr17_-_39782860 1.96 ENSRNOT00000042298
Prolactin family 3, subfamily d, member 1
chr8_-_114010277 1.96 ENSRNOT00000045087
ATPase secretory pathway Ca2+ transporting 1
chr1_+_68436593 1.94 ENSRNOT00000080325
leucyl-cystinyl aminopeptidase
chr2_+_93712992 1.94 ENSRNOT00000059326
fatty acid binding protein 12
chr1_+_95397991 1.93 ENSRNOT00000039649
zinc finger protein 939
chr3_-_55951584 1.92 ENSRNOT00000036585
FAST kinase domains 1
chr9_+_26841299 1.89 ENSRNOT00000016664
interleukin 17A
chr12_-_29958050 1.85 ENSRNOT00000058725
transmembrane protein 248
chr2_-_154508641 1.84 ENSRNOT00000065346
similar to hypothetical protein E130311K13
chr4_+_167017816 1.84 ENSRNOT00000055734
taste receptor, type 2, member 145
chr2_-_115307494 1.78 ENSRNOT00000072964
olfactory receptor 8D1-like
chr1_-_172943853 1.72 ENSRNOT00000047040
olfactory receptor 278
chr13_+_92504374 1.69 ENSRNOT00000033697
olfactory receptor 1602
chr2_+_41467064 1.68 ENSRNOT00000073231

chr17_-_42926523 1.68 ENSRNOT00000022512
prolactin family 3, subfamily d, member 4
chr9_-_5329305 1.68 ENSRNOT00000078055
solute carrier family 5 member 7
chr4_+_14109864 1.65 ENSRNOT00000076349
similar to fatty acid translocase/CD36
chr3_+_102947730 1.63 ENSRNOT00000071260
olfactory receptor 773
chr2_+_189857587 1.61 ENSRNOT00000048214
interleukin enhancer binding factor 2
chr2_+_243701962 1.59 ENSRNOT00000016891
alcohol dehydrogenase 4 (class II), pi polypeptide
chr8_+_17928358 1.59 ENSRNOT00000029911
methyl-CpG binding domain protein 3-like 2
chr7_-_139953999 1.57 ENSRNOT00000051304
olfactory receptor 1105
chr7_+_16394354 1.54 ENSRNOT00000041157
olfactory receptor 1058
chr1_-_71710374 1.51 ENSRNOT00000078556
ENSRNOT00000046152
NLR family, pyrin domain containing 4
chrX_+_45614888 1.40 ENSRNOT00000058473
uncharacterized LOC100909677
chr2_-_210454737 1.38 ENSRNOT00000079993
adenosylhomocysteinase-like 1
chr20_-_9291610 1.38 ENSRNOT00000000650
glyoxalase 1
chr1_-_173456488 1.37 ENSRNOT00000044753
olfactory receptor 282
chr4_-_179339795 1.31 ENSRNOT00000080410
branched chain amino acid transaminase 1
chr4_-_155690869 1.30 ENSRNOT00000012216
complement C3a receptor 1
chrX_-_159244879 1.27 ENSRNOT00000030445
MAP7 domain containing 3
chr1_-_149529350 1.24 ENSRNOT00000052226
vomeronasal 2 receptor, 43
chr10_+_36499361 1.23 ENSRNOT00000047984
olfactory receptor 1407
chr1_+_229063714 1.22 ENSRNOT00000087526
glycine-N-acyltransferase
chr1_+_62964901 1.19 ENSRNOT00000075013
vomeronasal 2 receptor, 22-like
chr16_+_8737974 1.18 ENSRNOT00000064255
ERCC excision repair 6, chromatin remodeling factor
chr8_-_113689681 1.17 ENSRNOT00000056435
similar to Nucleoside diphosphate-linked moiety X motif 16 (Nudix motif 16)
chr20_+_4143321 1.16 ENSRNOT00000060366
butyrophilin-like 2
chr2_-_118882562 1.16 ENSRNOT00000058860
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr14_-_86333424 1.15 ENSRNOT00000083191
NudC domain containing 3
chr3_+_76468294 1.13 ENSRNOT00000037779
olfactory receptor 619
chr1_-_168283863 1.13 ENSRNOT00000021115
olfactory receptor 80
chr10_-_12434118 1.12 ENSRNOT00000074072
olfactory receptor 1365
chr11_+_43340505 1.12 ENSRNOT00000043299
olfactory receptor 1541
chr3_+_75970593 1.11 ENSRNOT00000075834
olfactory receptor 592
chr20_-_5140304 1.07 ENSRNOT00000092646
proline-rich coiled-coil 2A
chr10_+_76320041 1.07 ENSRNOT00000037693
coilin
chr5_-_17399801 1.06 ENSRNOT00000011900
similar to protein tyrosine phosphatase 4a2
chr3_+_103556674 1.06 ENSRNOT00000050168
olfactory receptor 792
chr5_-_25721072 0.95 ENSRNOT00000021839
transmembrane protein 67
chr4_-_165828814 0.91 ENSRNOT00000007481
taste receptor, type 2, member 105
chr14_+_22072024 0.87 ENSRNOT00000002680
estrogen sulfotransferase
chr1_+_68436917 0.83 ENSRNOT00000088586
leucyl-cystinyl aminopeptidase
chr2_-_242828629 0.82 ENSRNOT00000043369
LRRGT00095
chr4_-_13565838 0.81 ENSRNOT00000048882
olfactory receptor 987
chr3_-_74597393 0.76 ENSRNOT00000013201
olfactory receptor 536
chr1_+_220071811 0.72 ENSRNOT00000090642

chrX_+_92131209 0.71 ENSRNOT00000004462
poly A binding protein, cytoplasmic 5
chr4_+_72272809 0.69 ENSRNOT00000048987
olfactory receptor 808
chr17_+_69960160 0.66 ENSRNOT00000023887
urocortin 3
chr6_-_51018050 0.65 ENSRNOT00000082691
G protein-coupled receptor 22
chr14_-_21707280 0.65 ENSRNOT00000002669
submaxillary gland androgen regulated protein 3A
chr5_+_103251986 0.55 ENSRNOT00000008757
centlein
chr10_+_36466229 0.55 ENSRNOT00000004865
olfactory receptor 1404
chr13_+_98311827 0.52 ENSRNOT00000082844
CDC42 binding protein kinase alpha
chr7_-_7311272 0.52 ENSRNOT00000040812
olfactory receptor 1020
chr3_-_173944396 0.50 ENSRNOT00000079019
synaptonemal complex protein 2
chr1_-_172465446 0.48 ENSRNOT00000088386
olfactory receptor 484-like
chrX_-_80354604 0.47 ENSRNOT00000049790
similar to MGC82337 protein
chr13_+_98231326 0.45 ENSRNOT00000003837
CDC42 binding protein kinase alpha
chrX_-_105417323 0.45 ENSRNOT00000015494
galactosidase, alpha
chr7_-_5195955 0.44 ENSRNOT00000040141
olfactory receptor 896
chrX_-_124002073 0.39 ENSRNOT00000072249
reproductive homeobox 9-like
chr15_-_4055539 0.38 ENSRNOT00000090352
SEC24 homolog C, COPII coat complex component
chr11_-_17340373 0.35 ENSRNOT00000089762

chr3_-_14571640 0.35 ENSRNOT00000060013
glycoprotein, alpha-galactosyltransferase 1-like 1
chr5_-_12199283 0.34 ENSRNOT00000007769
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr1_+_116869957 0.32 ENSRNOT00000075203
vomeronasal 2 receptor, 25
chr8_-_17860348 0.31 ENSRNOT00000046875
olfactory receptor 1118
chr17_+_1305016 0.31 ENSRNOT00000025965
ERCC excision repair 6 like 2
chr2_+_9526209 0.29 ENSRNOT00000021818
LysM domain containing 3
chr2_+_190628525 0.27 ENSRNOT00000023564
S100 calcium-binding protein, ventral prostate
chr16_+_70644474 0.25 ENSRNOT00000045955
ribosomal protein S28-like
chr3_-_76187045 0.24 ENSRNOT00000075650
similar to olfactory receptor 73
chr3_-_75576520 0.24 ENSRNOT00000083330
olfactory receptor 567
chr1_-_185569190 0.23 ENSRNOT00000090773
similar to sid2057p
chr12_-_40332612 0.12 ENSRNOT00000001691
ataxin 2
chr8_+_59420123 0.11 ENSRNOT00000077922
iron responsive element binding protein 2
chr5_-_56753832 0.08 ENSRNOT00000073045
SEC61 gamma subunit-like
chr13_+_76942928 0.05 ENSRNOT00000040505
ring finger and WD repeat domain 2
chr3_-_77605962 0.04 ENSRNOT00000090062
olfactory receptor 665
chrY_-_1398030 0.01 ENSRNOT00000088719
ubiquitin specific peptidase 9, Y-linked

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid3a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 19.8 GO:1901856 negative regulation of cellular respiration(GO:1901856)
3.2 22.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
2.9 8.7 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
2.9 11.5 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
2.8 11.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
2.6 7.7 GO:0090247 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
2.4 25.9 GO:0046710 GDP metabolic process(GO:0046710)
2.1 8.4 GO:0072318 clathrin coat disassembly(GO:0072318)
2.0 6.0 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.8 5.5 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
1.6 6.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.5 6.2 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
1.2 6.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
1.1 4.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
1.1 3.2 GO:1990168 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
1.1 3.2 GO:0042360 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) vitamin E metabolic process(GO:0042360) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.9 15.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.8 4.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.8 11.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.8 13.6 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.7 10.8 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.7 3.4 GO:0035617 stress granule disassembly(GO:0035617) regulation of voltage-gated sodium channel activity(GO:1905150)
0.7 2.0 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.7 3.9 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.6 6.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.5 2.1 GO:0050904 Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.5 7.8 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.4 1.3 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.4 1.3 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
0.4 1.9 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.4 7.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.4 3.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.3 1.7 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.3 3.0 GO:0071679 cytoskeletal anchoring at plasma membrane(GO:0007016) commissural neuron axon guidance(GO:0071679)
0.3 1.6 GO:0006069 ethanol oxidation(GO:0006069)
0.2 4.1 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 6.4 GO:0007413 axonal fasciculation(GO:0007413)
0.2 2.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 7.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 18.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.2 8.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 5.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 1.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.2 1.4 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.2 3.5 GO:0060736 prostate gland growth(GO:0060736)
0.1 3.1 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 2.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.5 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.1 1.7 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.1 2.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 6.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.9 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.1 12.2 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.1 9.2 GO:0008033 tRNA processing(GO:0008033)
0.1 1.2 GO:0005513 detection of calcium ion(GO:0005513)
0.1 2.6 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.1 15.8 GO:0006941 striated muscle contraction(GO:0006941)
0.1 1.0 GO:0007097 nuclear migration(GO:0007097)
0.1 6.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 8.2 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 1.2 GO:0006544 glycine metabolic process(GO:0006544)
0.1 3.9 GO:0007566 embryo implantation(GO:0007566)
0.1 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 2.0 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 2.3 GO:0030199 collagen fibril organization(GO:0030199)
0.1 9.3 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 2.9 GO:0042246 tissue regeneration(GO:0042246)
0.0 3.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.7 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 8.3 GO:0006790 sulfur compound metabolic process(GO:0006790)
0.0 3.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 43.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 6.8 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 30.6 GO:0055114 oxidation-reduction process(GO:0055114)
0.0 5.2 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 1.3 GO:0046785 microtubule polymerization(GO:0046785)
0.0 2.3 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 4.5 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.0 8.3 GO:0045596 negative regulation of cell differentiation(GO:0045596)
0.0 9.8 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 10.1 GO:0006629 lipid metabolic process(GO:0006629)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 30.7 GO:0005927 muscle tendon junction(GO:0005927)
3.8 11.3 GO:0044317 rod spherule(GO:0044317)
1.6 25.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
1.4 11.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
1.3 15.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.2 7.1 GO:0097441 basilar dendrite(GO:0097441)
0.7 5.9 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.7 6.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6 4.4 GO:0005827 polar microtubule(GO:0005827)
0.6 4.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.5 11.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 3.0 GO:0016011 dystroglycan complex(GO:0016011)
0.3 15.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 7.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 7.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 6.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 3.4 GO:0035253 ciliary rootlet(GO:0035253)
0.2 11.8 GO:0034707 chloride channel complex(GO:0034707)
0.2 6.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 12.2 GO:0005811 lipid particle(GO:0005811)
0.2 1.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 10.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 6.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 40.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 4.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 4.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.1 1.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 61.2 GO:0005739 mitochondrion(GO:0005739)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.0 8.0 GO:0014069 postsynaptic density(GO:0014069)
0.0 5.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0000800 lateral element(GO:0000800)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 5.8 GO:0043235 receptor complex(GO:0043235)
0.0 8.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.0 GO:0030133 transport vesicle(GO:0030133)
0.0 1.0 GO:0042641 actomyosin(GO:0042641)
0.0 2.1 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 43.5 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
2.9 8.7 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
2.8 22.2 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
2.7 10.8 GO:0045134 uridine-diphosphatase activity(GO:0045134)
2.6 25.9 GO:0004385 guanylate kinase activity(GO:0004385)
1.9 7.8 GO:0005143 interleukin-12 receptor binding(GO:0005143)
1.5 4.4 GO:0031208 POZ domain binding(GO:0031208)
1.3 3.9 GO:0047708 biotinidase activity(GO:0047708)
1.2 6.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
1.2 8.3 GO:0004065 arylsulfatase activity(GO:0004065)
1.1 5.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.1 15.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.1 3.2 GO:0052870 leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.9 14.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.8 3.4 GO:0099609 microtubule lateral binding(GO:0099609)
0.8 6.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.8 3.9 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.6 11.3 GO:0005522 profilin binding(GO:0005522)
0.6 3.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.6 7.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.6 6.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6 13.8 GO:0031489 myosin V binding(GO:0031489)
0.5 13.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.5 8.7 GO:0050811 GABA receptor binding(GO:0050811)
0.5 3.8 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.5 3.2 GO:0035375 zymogen binding(GO:0035375)
0.4 1.3 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 12.2 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.4 2.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.4 3.0 GO:0043237 laminin-1 binding(GO:0043237)
0.3 1.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 1.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 6.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 5.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 1.7 GO:0005148 prolactin receptor binding(GO:0005148)
0.3 5.4 GO:0010181 FMN binding(GO:0010181)
0.3 11.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.3 7.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 3.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 3.1 GO:0008143 poly(A) binding(GO:0008143)
0.2 1.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.2 2.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 0.7 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.2 2.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 10.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 3.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 3.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 2.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 12.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.3 GO:0004875 complement receptor activity(GO:0004875)
0.1 1.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.9 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.3 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 8.3 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.9 GO:0051787 misfolded protein binding(GO:0051787)
0.1 13.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 1.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 4.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 3.2 GO:0002039 p53 binding(GO:0002039)
0.0 1.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 43.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.1 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 4.1 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 4.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 4.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 3.2 GO:0019902 phosphatase binding(GO:0019902)
0.0 2.0 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 9.7 PID IL23 PATHWAY IL23-mediated signaling events
0.2 4.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 2.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 9.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 5.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 5.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 3.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 10.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 8.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 6.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.0 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 8.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.4 8.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.4 11.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.4 5.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.4 17.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.4 8.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 4.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 6.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 1.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 2.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 4.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 6.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 28.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 3.4 REACTOME KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.2 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors