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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Ar

Z-value: 0.91

Motif logo

Transcription factors associated with Ar

Gene Symbol Gene ID Gene Info
ENSRNOG00000005639 androgen receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Arrn6_v1_chrX_+_67656253_67656253-0.036.1e-01Click!

Activity profile of Ar motif

Sorted Z-values of Ar motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_138483612 35.84 ENSRNOT00000085620
solute carrier family 38, member 4
chr15_-_5509839 24.76 ENSRNOT00000080252
ENSRNOT00000081979
ENSRNOT00000085137
ENSRNOT00000049746
Spetex-2F protein
chr10_+_14519164 24.30 ENSRNOT00000079543
ENSRNOT00000046884
coiled-coil domain containing 154
chr4_-_98735346 23.76 ENSRNOT00000008473
testis expressed 37
chr13_+_51218468 22.70 ENSRNOT00000033636
similar to UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylgluco
chr10_+_103992309 21.54 ENSRNOT00000065292
tripartite motif protein 80
chr6_-_127630734 21.51 ENSRNOT00000089931
serpin family A member 1
chr17_+_72160735 21.17 ENSRNOT00000038817
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_4953879 21.13 ENSRNOT00000003455
transition protein 2
chr9_-_16095007 21.10 ENSRNOT00000073333

chr7_-_26144466 20.69 ENSRNOT00000009162
four and a half LIM domains 4
chr6_+_76349362 20.24 ENSRNOT00000043224
aldolase 1 A retrogene 2
chr10_-_56429748 19.87 ENSRNOT00000020675
ENSRNOT00000092704
spermatid maturation 1
chr2_-_243475639 19.34 ENSRNOT00000089222
similar to hypothetical protein DKFZp434G072
chr5_-_58309627 19.28 ENSRNOT00000031509
ENSRNOT00000085709
family with sequence similarity 205, member C
chr1_-_189238776 18.70 ENSRNOT00000020817
protein disulfide isomerase-like, testis expressed
chr6_-_47848026 18.16 ENSRNOT00000011048
ENSRNOT00000090017
allantoicase
chr16_+_29674793 17.83 ENSRNOT00000059724
annexin A10
chr15_-_5467047 17.70 ENSRNOT00000042743
Spetex-2F protein
chr1_-_162533893 16.91 ENSRNOT00000016783
adipogenesis associated, Mth938 domain containing
chr5_-_122828398 16.56 ENSRNOT00000030112
hypothetical gene supported by BC079057
chr13_+_91080341 16.55 ENSRNOT00000000058
C-reactive protein
chr10_+_49368314 16.24 ENSRNOT00000004392
CMT1A duplicated region transcript 4
chr17_-_8619737 15.87 ENSRNOT00000065217
RGD1562024
chr3_+_143129248 15.79 ENSRNOT00000006667
cystatin 8
chr5_-_127273656 15.41 ENSRNOT00000057341
DMRT-like family B with proline-rich C-terminal, 1
chr10_+_4950484 15.40 ENSRNOT00000003450
protamine 2
chr7_-_100382897 15.22 ENSRNOT00000006510
LOC500876
chr5_+_124442293 15.06 ENSRNOT00000041922
similar to novel protein
chr6_-_47811853 14.85 ENSRNOT00000010942
allantoicase
chr15_-_42751330 14.67 ENSRNOT00000066478
ADAM metallopeptidase domain 2
chr5_+_136117858 14.59 ENSRNOT00000087764
transmembrane protein 53
chr6_-_26624092 14.54 ENSRNOT00000008113
tripartite motif-containing 54
chr17_+_56935451 14.51 ENSRNOT00000058966
similar to hypothetical protein 4930474N05
chr16_+_12976906 14.44 ENSRNOT00000029573
similar to Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS)
chr13_+_109646455 14.41 ENSRNOT00000073985
hypothetical LOC498316
chr16_-_12742010 14.32 ENSRNOT00000077513
ral guanine nucleotide dissociation stimulator-like
chr15_+_67092304 14.30 ENSRNOT00000040244

chr5_-_27180819 14.18 ENSRNOT00000045483

chr6_+_110749705 14.00 ENSRNOT00000084348
leucine rich repeat containing 74A
chr4_-_6062641 13.95 ENSRNOT00000074846
chaperonin containing TCP1, subunit 8 (theta)-like 1
chr5_-_73494030 13.93 ENSRNOT00000022291
actin-like 7b
chr7_+_2689501 13.88 ENSRNOT00000041341
apolipoprotein F
chr6_-_23543172 13.86 ENSRNOT00000006073
speedy/RINGO cell cycle regulator family member A
chr3_+_151609602 13.81 ENSRNOT00000065052
sperm associated antigen 4
chr2_+_104290726 13.76 ENSRNOT00000017387
DnaJ heat shock protein family (Hsp40) member C5 beta
chr1_+_201337416 13.61 ENSRNOT00000067742
BTB domain containing 16
chr3_+_152143811 13.51 ENSRNOT00000026578
sperm-associated antigen 4 protein-like
chr1_-_206394346 13.26 ENSRNOT00000038122
hypothetical LOC100302465
chr1_+_18353812 13.25 ENSRNOT00000029394

chr1_-_154507039 13.16 ENSRNOT00000078883
coiled-coil domain containing 83
chr1_+_267618565 13.03 ENSRNOT00000076251
glutathione S-transferase omega 2
chr15_-_5417570 12.97 ENSRNOT00000061525
Spetex-2F protein
chr20_-_25826658 12.91 ENSRNOT00000057950
ENSRNOT00000084660
catenin alpha 3
chr10_-_107376645 12.59 ENSRNOT00000046213
CEP295 N-terminal like
chr5_-_108747666 12.41 ENSRNOT00000072732
zinc finger protein 353
chr10_-_43892604 12.30 ENSRNOT00000003801
similar to RIKEN cDNA 4930504O13
chr17_+_45175121 11.99 ENSRNOT00000080417
NFKB activating protein-like
chr1_-_143398093 11.97 ENSRNOT00000078916
fibronectin type III and SPRY domain containing 2
chr10_+_96639924 11.73 ENSRNOT00000004756
apolipoprotein H
chrX_-_97262013 11.70 ENSRNOT00000040168
claudin 34C4
chr16_-_12662336 11.66 ENSRNOT00000080161
similar to hypothetical protein 4930474N05
chr13_+_75177965 11.63 ENSRNOT00000007321
SEC16 homolog B, endoplasmic reticulum export factor
chrX_+_709306 11.46 ENSRNOT00000071047
synovial sarcoma, X breakpoint 2
chr13_-_74005486 11.35 ENSRNOT00000090173

chr14_+_94776233 11.22 ENSRNOT00000070839

chr1_+_83043760 11.19 ENSRNOT00000074720
carcinoembryonic antigen-related cell adhesion molecule 1-like
chr3_-_72219246 11.15 ENSRNOT00000009903
smoothelin-like 1
chr3_-_51054378 11.14 ENSRNOT00000089243
growth factor receptor bound protein 14
chr2_-_216443518 11.01 ENSRNOT00000022496
amylase, alpha 1A
chr6_-_27323992 10.96 ENSRNOT00000013198
similar to RIKEN cDNA 1700001C02
chr19_-_26082719 10.95 ENSRNOT00000083159
ribonuclease H2, subunit A
chr6_+_128073344 10.80 ENSRNOT00000014073
Ab1-233
chr8_-_132910905 10.59 ENSRNOT00000008630
FYVE and coiled-coil domain containing 1
chrX_-_106576314 10.37 ENSRNOT00000037823
nuclear RNA export factor 3
chr11_-_36533073 10.33 ENSRNOT00000033486
LCA5L, lebercilin like
chr1_-_205630073 10.31 ENSRNOT00000037064
testis expressed 36
chr11_+_64488194 10.29 ENSRNOT00000030268
similar to hypothetical protein FLJ32859
chr3_+_170475831 10.28 ENSRNOT00000006949
family with sequence similarity 209, member A
chr9_+_95309759 10.25 ENSRNOT00000051438
maestro heat-like repeat family member 2A
chr20_+_5170215 10.06 ENSRNOT00000001139
natural cytotoxicity triggering receptor 3
chr6_-_127816055 10.03 ENSRNOT00000013175
serine (or cysteine) proteinase inhibitor, clade A, member 3M
chr6_+_26780352 10.00 ENSRNOT00000009916
proline rich 30
chrX_+_62366453 9.98 ENSRNOT00000089828
aristaless related homeobox
chr10_-_56426012 9.86 ENSRNOT00000092506
ENSRNOT00000084068
similar to RIKEN cDNA 4933402P03
chr10_-_5511955 9.85 ENSRNOT00000039429
activating transcription factor 7 interacting protein 2
chr3_-_148073554 9.80 ENSRNOT00000055407
defensin beta 27
chr15_-_28314459 9.72 ENSRNOT00000042055
ENSRNOT00000040540
NDRG family member 2
chr2_-_208633945 9.68 ENSRNOT00000049155
primary cilia formation
chr12_+_45319501 9.66 ENSRNOT00000090630
ENSRNOT00000041732
similar to hypothetical protein 4930474N05
chr20_-_32115310 9.66 ENSRNOT00000067883
ENSRNOT00000081916
VPS26 retromer complex component A
chr4_+_1470716 9.64 ENSRNOT00000044223
olfactory receptor 1235
chrX_-_71681073 9.55 ENSRNOT00000037212
rCG64283-like
chr9_-_27447877 9.53 ENSRNOT00000085195
glutathione S-transferase alpha 1
chr5_+_58752879 9.44 ENSRNOT00000071201
ATPase, class I, type 8B, member 5, pseudogene
chr4_-_69149520 9.41 ENSRNOT00000017611
protease, serine, 58
chr11_-_57993548 9.28 ENSRNOT00000002957
nectin cell adhesion molecule 3
chr20_-_4542947 9.26 ENSRNOT00000086140
complement factor B
chr4_+_57823411 9.24 ENSRNOT00000030462
ENSRNOT00000088235
serine-rich single-pass membrane protein 1
chr6_-_135026449 9.10 ENSRNOT00000009444
hypothetical LOC299330
chr1_+_81372650 9.02 ENSRNOT00000088829
zinc finger protein 428
chr15_+_108453147 8.98 ENSRNOT00000018486
translocase of inner mitochondrial membrane 8A2
chr4_-_178168690 8.95 ENSRNOT00000020729
SRY box 5
chr8_+_5893249 8.81 ENSRNOT00000014041
matrix metallopeptidase 7
chr7_+_141953794 8.62 ENSRNOT00000041938
transmembrane protease, serine 12
chr7_-_80796670 8.50 ENSRNOT00000010539
actin-binding Rho activating protein
chr3_-_2719513 8.48 ENSRNOT00000020997
lipocalin 12
chr3_+_154986059 8.41 ENSRNOT00000082528
adipogenin-like
chr16_+_6970342 8.40 ENSRNOT00000061294
ENSRNOT00000048344
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr9_+_27402381 8.40 ENSRNOT00000077372
glutathione S-transferase alpha 3
chr1_-_18511695 8.37 ENSRNOT00000075402

chr8_-_72841496 8.32 ENSRNOT00000057641
ENSRNOT00000040808
ENSRNOT00000085894
ENSRNOT00000024575
ENSRNOT00000048044
ENSRNOT00000024493
tropomyosin 1, alpha
chr19_+_50246402 8.32 ENSRNOT00000018795
hydroxysteroid (17-beta) dehydrogenase 2
chr8_-_107490093 8.12 ENSRNOT00000046832
similar to Fas apoptotic inhibitory molecule 1 (rFAIM)
chr14_+_26662965 8.11 ENSRNOT00000002621
trans-2,3-enoyl-CoA reductase-like
chr7_+_12941994 8.07 ENSRNOT00000010832
outer dense fiber of sperm tails 3-like 2
chr3_-_161027943 8.02 ENSRNOT00000078633
serine peptidase inhibitor, Kunitz type, 3
chr7_-_117267803 7.97 ENSRNOT00000082271
plectin
chr7_-_117267402 7.70 ENSRNOT00000088945
plectin
chr13_-_85695421 7.64 ENSRNOT00000005768
leucine rich repeat containing 52
chr13_+_70157522 7.58 ENSRNOT00000036906
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr13_+_52889737 7.56 ENSRNOT00000074366
calcium voltage-gated channel subunit alpha1 S
chr7_-_117259141 7.55 ENSRNOT00000040762
plectin
chr1_+_260051406 7.51 ENSRNOT00000079734

chr4_-_100099517 7.50 ENSRNOT00000014277
atonal bHLH transcription factor 8
chr1_+_142034423 7.49 ENSRNOT00000090006
tubulin tyrosine ligase-like family, member 13
chr7_-_12518684 7.46 ENSRNOT00000018691
ENSRNOT00000093426
glutathione peroxidase 4
chr1_-_198104109 7.43 ENSRNOT00000026186
sulfotransferase family 1A member 1
chr1_-_19522171 7.36 ENSRNOT00000045386

chr4_-_6046477 7.33 ENSRNOT00000073925
chaperonin containing TCP1, subunit 8 (theta)-like 1
chr19_+_15094309 7.27 ENSRNOT00000083500
carboxylesterase 1F
chr3_+_143109316 7.17 ENSRNOT00000006555
cystatin SC
chr20_-_13667333 7.12 ENSRNOT00000031472
coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial
chr13_+_83073866 7.03 ENSRNOT00000075996
dermatopontin
chrX_+_72684329 7.01 ENSRNOT00000057644
DMRT-like family C1c1
chr3_+_2438089 6.97 ENSRNOT00000013335
family with sequence similarity 166, member A
chr2_+_127770676 6.93 ENSRNOT00000068405
abhydrolase domain containing 18
chr7_-_117259791 6.81 ENSRNOT00000086550
plectin
chr1_-_88723973 6.68 ENSRNOT00000082555
WD repeat domain 62-like 1
chr9_+_41006800 6.65 ENSRNOT00000079413
ENSRNOT00000034214
protease, serine, 39
chr19_-_11302938 6.64 ENSRNOT00000038212

chr2_-_184951950 6.61 ENSRNOT00000093486
family with sequence similarity 160, member A1
chr2_+_178117466 6.58 ENSRNOT00000065115
ENSRNOT00000084198
similar to hypothetical protein FLJ25371
chr13_-_51373399 6.52 ENSRNOT00000060656
MGAT4 family, member E
chr4_-_181348799 6.47 ENSRNOT00000033743
hypothetical protein LOC690783
chr9_+_94228960 6.41 ENSRNOT00000083137
ENSRNOT00000080897
alkaline phosphatase 3, intestine, not Mn requiring
chr9_-_113900190 6.38 ENSRNOT00000016965
NADH:ubiquinone oxidoreductase core subunit V2
chr20_+_34633157 6.34 ENSRNOT00000000469
phospholamban
chr15_+_18332910 6.28 ENSRNOT00000085822
family with sequence similarity 3, member D
chr5_-_164585634 6.27 ENSRNOT00000065985
mitofusin 2
chr16_-_8350067 6.20 ENSRNOT00000026932
mitochondrial import inner membrane translocase subunit Tim23-like
chr1_+_221443896 6.18 ENSRNOT00000073942
transmembrane protein 262
chr5_+_154112076 6.15 ENSRNOT00000044969
myomesin 3
chr13_-_52834134 6.12 ENSRNOT00000038874
immunoglobulin-like and fibronectin type III domain containing 1
chr12_+_45026886 6.09 ENSRNOT00000001500
phosphatidylethanolamine binding protein 1
chr7_-_117719605 6.03 ENSRNOT00000077172
cysteine and histidine rich 1
chr5_+_172825072 6.01 ENSRNOT00000068525
cilia and flagella associated protein 74
chr1_+_89008117 5.94 ENSRNOT00000028401
heat shock protein family B (small) member 6
chr16_-_49318383 5.92 ENSRNOT00000045721
cilia and flagella associated protein 97
chr10_-_11942885 5.90 ENSRNOT00000061019
olfactory receptor 1356
chr7_-_117268300 5.82 ENSRNOT00000091840
plectin
chr16_+_75083172 5.65 ENSRNOT00000058002
defensin beta 37
chr1_-_216953999 5.62 ENSRNOT00000028126
MAS related GPR family member G
chr2_-_185168476 5.59 ENSRNOT00000093447
family with sequence similarity 160, member A1
chr12_-_31249118 5.57 ENSRNOT00000058586
ENSRNOT00000073105
adhesion G protein-coupled receptor D1
chr3_-_80543031 5.57 ENSRNOT00000022233
coagulation factor II
chr2_+_104020955 5.53 ENSRNOT00000045586
mitochondrial fission regulator 1
chr20_-_30947484 5.52 ENSRNOT00000065614
phosphatase domain containing, paladin 1
chr20_+_3364814 5.45 ENSRNOT00000001077
hypothetical protein MGC:15854
chr10_-_75120247 5.43 ENSRNOT00000011402
lactoperoxidase
chr2_-_3124543 5.39 ENSRNOT00000036547
family with sequence similarity 81, member B
chr16_+_50181316 5.35 ENSRNOT00000077662
coagulation factor XI
chr4_+_148649223 5.35 ENSRNOT00000040801
olfactory receptor 829
chr5_+_58393233 5.32 ENSRNOT00000000142
DnaJ heat shock protein family (Hsp40) member B5
chr6_+_26546924 5.30 ENSRNOT00000007763
eukaryotic translation initiation factor 2B subunit delta
chr13_+_99335020 5.29 ENSRNOT00000029787

chr7_+_143754892 5.25 ENSRNOT00000085896
sterol O-acyltransferase 2
chr1_-_94610854 5.20 ENSRNOT00000020383
pleckstrin homology and FYVE domain containing 1
chr5_-_110326940 5.15 ENSRNOT00000049470
zinc finger protein 352
chr1_+_282567674 5.14 ENSRNOT00000090543
carboxylesterase 2I
chr16_-_7681576 5.09 ENSRNOT00000026550
collagen like tail subunit of asymmetric acetylcholinesterase
chr1_-_216942782 5.08 ENSRNOT00000049057
similar to MAS-related G-protein coupled receptor, member G
chr3_+_2182957 5.08 ENSRNOT00000011633
patatin-like phospholipase domain containing 7
chr2_-_119537837 5.05 ENSRNOT00000015200
peroxisomal biogenesis factor 5-like
chr4_-_115453659 4.98 ENSRNOT00000065847
testis expressed 261
chr8_+_56411911 4.93 ENSRNOT00000039083
mitochondrial ribosomal protein L1-like
chr4_-_176606382 4.93 ENSRNOT00000065576
RecQ like helicase
chr1_-_170694872 4.83 ENSRNOT00000075443
olfactory receptor 2D3-like
chr4_-_27726943 4.83 ENSRNOT00000068499
similar to EF hand calcium binding domain 1
chr5_+_58393603 4.79 ENSRNOT00000080082
DnaJ heat shock protein family (Hsp40) member B5
chr10_-_62699723 4.79 ENSRNOT00000086706
coronin 6
chr1_+_171274305 4.76 ENSRNOT00000051038
olfactory receptor 234
chr1_+_203160323 4.75 ENSRNOT00000027919

chr3_-_94419048 4.71 ENSRNOT00000015775
homeodomain interacting protein kinase 3
chr6_-_38453797 4.71 ENSRNOT00000009100
DEAD-box helicase 1
chr15_-_29856947 4.63 ENSRNOT00000066990

chr10_+_35857797 4.59 ENSRNOT00000004517
chibby family member 3
chr15_+_108286453 4.55 ENSRNOT00000016986
UBA domain containing 2
chr8_+_85951191 4.53 ENSRNOT00000037665
CD109 molecule
chr1_-_212022212 4.51 ENSRNOT00000074298
cilia and flagella associated protein 46

Network of associatons between targets according to the STRING database.

First level regulatory network of Ar

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.0 33.0 GO:0043605 cellular amide catabolic process(GO:0043605)
7.2 21.5 GO:0033986 response to methanol(GO:0033986)
3.4 10.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
3.0 21.1 GO:0007341 penetration of zona pellucida(GO:0007341)
2.9 8.8 GO:0002777 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
2.9 11.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
2.8 8.4 GO:1901377 toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
2.8 8.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
2.4 9.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
2.2 11.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
1.9 35.9 GO:0031581 hemidesmosome assembly(GO:0031581)
1.9 5.6 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) response to thyrotropin-releasing hormone(GO:1905225)
1.8 10.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
1.7 13.8 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
1.7 10.0 GO:0021759 globus pallidus development(GO:0021759)
1.6 12.9 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
1.5 8.9 GO:2000741 regulation of timing of neuron differentiation(GO:0060164) positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.4 13.0 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
1.4 4.3 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
1.4 4.2 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
1.4 4.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.3 18.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
1.3 3.9 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.3 3.9 GO:1904753 negative regulation of hematopoietic stem cell differentiation(GO:1902037) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
1.3 11.6 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
1.3 16.6 GO:0010988 negative regulation of macrophage derived foam cell differentiation(GO:0010745) regulation of low-density lipoprotein particle clearance(GO:0010988)
1.2 3.6 GO:1990108 protein linear deubiquitination(GO:1990108)
1.2 2.4 GO:0060166 olfactory pit development(GO:0060166)
1.2 9.3 GO:1902414 protein localization to cell junction(GO:1902414)
1.1 5.5 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
1.1 7.6 GO:0002074 extraocular skeletal muscle development(GO:0002074)
1.1 3.2 GO:0006106 fumarate metabolic process(GO:0006106) glycerol biosynthetic process(GO:0006114) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
1.1 7.4 GO:0009812 flavonoid metabolic process(GO:0009812)
1.0 11.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.0 5.9 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.9 8.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.9 5.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.9 4.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.9 9.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.8 5.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.8 4.9 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.8 2.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.8 2.4 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.8 3.2 GO:0035617 stress granule disassembly(GO:0035617)
0.8 2.4 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.8 6.3 GO:1990910 response to hypobaric hypoxia(GO:1990910)
0.8 5.4 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.8 4.5 GO:0072675 osteoclast fusion(GO:0072675)
0.7 10.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.7 2.9 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.7 5.0 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.7 22.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.7 2.7 GO:0050787 detoxification of mercury ion(GO:0050787)
0.7 6.1 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.7 4.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.7 0.7 GO:0035262 gonad morphogenesis(GO:0035262)
0.7 5.3 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.6 17.2 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.6 3.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.6 1.8 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.6 21.3 GO:0006458 'de novo' protein folding(GO:0006458)
0.5 2.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.5 3.7 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.5 8.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.5 5.6 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.5 1.4 GO:0048850 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.4 4.9 GO:0000733 DNA strand renaturation(GO:0000733)
0.4 1.8 GO:1903413 cellular response to bile acid(GO:1903413)
0.4 1.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.4 4.6 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.4 11.0 GO:0006298 mismatch repair(GO:0006298)
0.4 9.7 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.4 3.2 GO:0035878 nail development(GO:0035878)
0.4 1.9 GO:0042262 dGTP catabolic process(GO:0006203) DNA protection(GO:0042262)
0.4 4.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.4 1.1 GO:0006083 acetate metabolic process(GO:0006083)
0.4 7.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.4 14.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.4 1.9 GO:0060005 vestibular reflex(GO:0060005)
0.4 1.5 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.4 14.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.4 4.3 GO:0046549 retinal cone cell development(GO:0046549)
0.4 11.1 GO:0030261 chromosome condensation(GO:0030261)
0.3 1.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.3 1.7 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.3 9.4 GO:0045332 phospholipid translocation(GO:0045332)
0.3 6.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3 4.8 GO:0050872 white fat cell differentiation(GO:0050872)
0.3 4.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.3 4.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.3 0.9 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.3 10.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.3 2.1 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.3 0.9 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.3 1.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.3 1.4 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.3 0.8 GO:0000958 mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962)
0.3 15.1 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.3 20.2 GO:0006096 glycolytic process(GO:0006096)
0.3 1.0 GO:0019471 glyoxylate catabolic process(GO:0009436) 4-hydroxyproline metabolic process(GO:0019471)
0.3 2.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.3 2.5 GO:0030953 astral microtubule organization(GO:0030953)
0.3 6.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 1.7 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.2 1.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 19.9 GO:0030317 sperm motility(GO:0030317)
0.2 11.1 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.2 3.9 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 2.4 GO:0009437 carnitine metabolic process(GO:0009437)
0.2 4.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 6.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 8.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 1.6 GO:0046655 folic acid metabolic process(GO:0046655)
0.2 1.0 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.2 0.9 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 15.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 6.4 GO:0033344 cholesterol efflux(GO:0033344)
0.2 1.4 GO:0009650 UV protection(GO:0009650)
0.2 7.0 GO:0030199 collagen fibril organization(GO:0030199)
0.2 2.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 0.7 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.2 0.8 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 5.5 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 2.0 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.1 0.1 GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
0.1 1.4 GO:0030238 male sex determination(GO:0030238)
0.1 0.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 2.8 GO:0045116 protein neddylation(GO:0045116)
0.1 1.2 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.1 1.6 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 4.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 1.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 6.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 2.5 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.1 1.9 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 1.2 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.7 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 11.0 GO:0007338 single fertilization(GO:0007338)
0.1 11.1 GO:0006457 protein folding(GO:0006457)
0.1 5.2 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 1.0 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 4.6 GO:0045103 intermediate filament-based process(GO:0045103)
0.1 0.5 GO:0015825 L-serine transport(GO:0015825)
0.1 0.9 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1 1.3 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.1 0.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 1.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 2.7 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 3.9 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.1 5.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 0.1 GO:0072244 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 2.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 1.2 GO:0006301 postreplication repair(GO:0006301)
0.1 69.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.6 GO:0014850 response to muscle activity(GO:0014850)
0.0 1.8 GO:1901031 regulation of response to reactive oxygen species(GO:1901031)
0.0 3.5 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 1.0 GO:0097186 amelogenesis(GO:0097186)
0.0 2.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 1.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 1.3 GO:0071806 protein transmembrane transport(GO:0071806)
0.0 0.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 16.2 GO:0005975 carbohydrate metabolic process(GO:0005975)
0.0 1.1 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.4 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 1.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 3.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.6 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 4.4 GO:0006397 mRNA processing(GO:0006397)
0.0 0.4 GO:0018149 peptide cross-linking(GO:0018149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 11.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
2.4 9.7 GO:0030906 retromer, cargo-selective complex(GO:0030906)
2.3 31.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
2.1 6.3 GO:0090534 calcium ion-transporting ATPase complex(GO:0090534)
2.0 11.7 GO:0042627 chylomicron(GO:0042627)
1.7 35.9 GO:0030056 hemidesmosome(GO:0030056)
1.2 8.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.2 13.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.9 5.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.9 21.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.9 9.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.6 6.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.6 4.7 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.6 2.4 GO:0061474 phagolysosome membrane(GO:0061474)
0.5 4.9 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.5 17.3 GO:0031430 M band(GO:0031430)
0.4 4.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.4 3.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 2.1 GO:0005579 membrane attack complex(GO:0005579)
0.4 1.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.4 9.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.3 2.3 GO:0030312 external encapsulating structure(GO:0030312)
0.3 38.9 GO:0072562 blood microparticle(GO:0072562)
0.3 4.1 GO:0032426 stereocilium tip(GO:0032426)
0.3 3.6 GO:0097542 ciliary tip(GO:0097542)
0.3 0.8 GO:0045025 mitochondrial degradosome(GO:0045025)
0.3 1.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 35.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 12.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 1.9 GO:0097452 GAIT complex(GO:0097452)
0.2 4.5 GO:0005916 fascia adherens(GO:0005916)
0.2 9.6 GO:0001772 immunological synapse(GO:0001772)
0.2 0.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 0.7 GO:0070110 interleukin-6 receptor complex(GO:0005896) ciliary neurotrophic factor receptor complex(GO:0070110)
0.2 18.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 2.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 5.2 GO:0005605 basal lamina(GO:0005605)
0.2 1.8 GO:0061700 GATOR2 complex(GO:0061700)
0.2 3.5 GO:0005922 connexon complex(GO:0005922)
0.2 2.0 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 23.9 GO:0031514 motile cilium(GO:0031514)
0.2 30.6 GO:0030017 sarcomere(GO:0030017)
0.1 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.1 GO:1990836 lysosomal matrix(GO:1990836)
0.1 5.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 6.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 2.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 7.1 GO:0045095 keratin filament(GO:0045095)
0.1 10.6 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.8 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 3.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 3.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 5.7 GO:0036064 ciliary basal body(GO:0036064)
0.1 4.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.5 GO:0016592 mediator complex(GO:0016592)
0.0 4.7 GO:0016605 PML body(GO:0016605)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 8.0 GO:0030426 growth cone(GO:0030426)
0.0 3.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 2.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 4.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 4.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
3.7 11.0 GO:0004556 alpha-amylase activity(GO:0004556)
3.3 13.0 GO:0030614 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
2.9 20.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.5 7.4 GO:0050656 steroid sulfotransferase activity(GO:0050294) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
2.4 16.6 GO:0001849 complement component C1q binding(GO:0001849)
2.3 18.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
2.3 29.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
2.2 11.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.4 12.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.2 8.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
1.1 3.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.1 31.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
1.0 5.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
1.0 35.9 GO:0030506 ankyrin binding(GO:0030506)
1.0 3.9 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.9 7.5 GO:0008430 selenium binding(GO:0008430)
0.9 6.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.8 4.9 GO:0009378 four-way junction helicase activity(GO:0009378)
0.8 4.0 GO:0004977 melanocortin receptor activity(GO:0004977)
0.8 6.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.8 2.4 GO:0052871 leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.7 10.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.7 2.1 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
0.7 4.2 GO:0004144 2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
0.7 5.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.7 3.5 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.7 6.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.7 77.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.6 1.9 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.6 1.9 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.6 11.2 GO:0005523 tropomyosin binding(GO:0005523)
0.6 3.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.6 2.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.5 4.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.5 1.6 GO:0098603 selenol Se-methyltransferase activity(GO:0098603)
0.5 2.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.5 8.5 GO:0001972 retinoic acid binding(GO:0001972)
0.5 9.5 GO:0043295 glutathione binding(GO:0043295)
0.5 5.5 GO:0046870 cadmium ion binding(GO:0046870)
0.5 2.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.5 1.4 GO:0016414 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
0.4 5.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.4 2.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 3.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 9.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.4 1.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.4 2.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.4 4.9 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 5.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.4 1.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.4 4.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.4 7.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 1.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.3 7.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.3 1.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.3 1.3 GO:0004645 phosphorylase activity(GO:0004645)
0.3 2.5 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.3 8.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 1.8 GO:0070728 leucine binding(GO:0070728)
0.3 4.7 GO:0008143 poly(A) binding(GO:0008143)
0.3 10.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.3 3.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 6.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 1.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 8.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 3.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 5.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 3.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 3.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 16.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 16.1 GO:0051082 unfolded protein binding(GO:0051082)
0.2 1.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 5.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 5.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 1.9 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 2.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 4.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 0.7 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.2 9.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 2.8 GO:0097602 cullin family protein binding(GO:0097602)
0.2 7.5 GO:0070888 E-box binding(GO:0070888)
0.2 1.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 5.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 15.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 17.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.3 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 1.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 2.4 GO:0071837 HMG box domain binding(GO:0071837)
0.1 3.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102) transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.7 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 21.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 1.2 GO:0051378 serotonin binding(GO:0051378)
0.1 17.7 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.1 2.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.3 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 1.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.1 1.1 GO:0010181 FMN binding(GO:0010181)
0.1 2.4 GO:0005109 frizzled binding(GO:0005109)
0.1 67.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 53.4 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.7 GO:0001618 virus receptor activity(GO:0001618)
0.0 4.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 1.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 8.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.1 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.8 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 3.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0019825 oxygen binding(GO:0019825)
0.0 1.3 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 0.8 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.6 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.7 GO:0031490 chromatin DNA binding(GO:0031490)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 14.8 ST GA12 PATHWAY G alpha 12 Pathway
0.4 19.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 60.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 6.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 11.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 9.6 PID AURORA B PATHWAY Aurora B signaling
0.1 4.2 PID IL23 PATHWAY IL23-mediated signaling events
0.1 3.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 4.3 PID EPO PATHWAY EPO signaling pathway
0.1 3.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 5.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 4.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 11.0 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
1.0 31.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
1.0 11.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.0 9.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.9 27.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6 7.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.6 5.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.5 11.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.5 18.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 4.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 5.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 8.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 8.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 2.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 3.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 12.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 7.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 2.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 2.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 12.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 3.5 REACTOME KINESINS Genes involved in Kinesins
0.1 3.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 3.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 4.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation