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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Alx4

Z-value: 0.96

Motif logo

Transcription factors associated with Alx4

Gene Symbol Gene ID Gene Info
ENSRNOG00000000008 ALX homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Alx4rn6_v1_chr3_+_82548959_825489590.291.1e-07Click!

Activity profile of Alx4 motif

Sorted Z-values of Alx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_33606124 36.81 ENSRNOT00000065210

chr2_+_248398917 31.06 ENSRNOT00000045855
guanylate binding protein 1
chr5_-_161981441 26.25 ENSRNOT00000020316
podoplanin
chr5_-_17061837 23.66 ENSRNOT00000011892
proenkephalin
chr8_-_84506328 22.86 ENSRNOT00000064754
muscular LMNA-interacting protein
chr4_-_129619142 22.18 ENSRNOT00000047453
leiomodin 3
chr8_-_78096302 20.99 ENSRNOT00000086185
ENSRNOT00000077999
myocardial zonula adherens protein
chr15_+_87722221 20.94 ENSRNOT00000082688
sciellin
chr4_+_144382945 20.91 ENSRNOT00000007601
caveolin 3
chr5_-_17061361 20.89 ENSRNOT00000089318
proenkephalin
chr17_+_23661429 20.42 ENSRNOT00000046523
phosphatase and actin regulator 1
chr11_+_36555416 19.68 ENSRNOT00000064981
SH3 domain binding glutamate-rich protein
chr4_+_155321553 19.64 ENSRNOT00000089614
microfibrillar associated protein 5
chr12_-_5685448 17.91 ENSRNOT00000077167
FRY microtubule binding protein
chr10_+_69412017 17.82 ENSRNOT00000009448
C-C motif chemokine ligand 2
chr17_+_63635086 17.21 ENSRNOT00000020634
disco-interacting protein 2 homolog C
chr2_+_219598162 16.78 ENSRNOT00000020297
leucine rich repeat containing 39
chr5_+_64476317 16.37 ENSRNOT00000017217
collagen alpha-1(XV) chain-like
chr14_-_77810147 16.15 ENSRNOT00000035427
cytokine like 1
chr13_-_84331905 15.59 ENSRNOT00000004965
dual specificity phosphatase 27 (putative)
chr4_-_157304653 15.19 ENSRNOT00000051613
leucine rich repeat containing 23
chr19_+_27404712 14.90 ENSRNOT00000023657
myosin light chain kinase 3
chr2_-_96509424 14.76 ENSRNOT00000090866
zinc finger, C2HC-type containing 1A
chr18_+_55666027 14.66 ENSRNOT00000045950
similar to CDNA sequence BC023105
chr9_+_20241062 14.61 ENSRNOT00000071593
leucine-rich repeat-containing protein 23-like
chr2_-_158156444 13.79 ENSRNOT00000088559
ventricular zone expressed PH domain-containing 1
chr17_-_84247038 13.73 ENSRNOT00000068553
nebulette
chr4_+_180291389 13.45 ENSRNOT00000002465
sarcospan
chr1_+_8310577 13.30 ENSRNOT00000015131
human immunodeficiency virus type I enhancer binding protein 2
chr16_+_29674793 12.98 ENSRNOT00000059724
annexin A10
chr4_+_158088505 12.83 ENSRNOT00000026643
von Willebrand factor
chr15_-_95514259 12.67 ENSRNOT00000038433
SLIT and NTRK-like family, member 6
chr1_-_215033460 12.24 ENSRNOT00000044565
dual specificity phosphatase 8
chr13_-_82005741 11.84 ENSRNOT00000076404
methyltransferase like 11B
chr13_-_82006005 11.83 ENSRNOT00000039581
methyltransferase like 11B
chr18_-_26656879 11.73 ENSRNOT00000086729
erythrocyte membrane protein band 4.1 like 4A
chr13_+_82369493 11.67 ENSRNOT00000003733
selectin L
chr13_+_87986240 11.47 ENSRNOT00000003705
regulator of G-protein signaling 5
chr2_+_58724855 11.47 ENSRNOT00000089609
calcyphosine-like
chr4_-_41212072 11.33 ENSRNOT00000085596
protein phosphatase 1, regulatory subunit 3A
chr1_-_278042312 11.32 ENSRNOT00000018693
actin-binding LIM protein 1
chrX_-_14972675 11.06 ENSRNOT00000079664
solute carrier family 38, member 5
chr12_-_31249118 10.79 ENSRNOT00000058586
ENSRNOT00000073105
adhesion G protein-coupled receptor D1
chr4_-_109532234 10.78 ENSRNOT00000008665
regenerating family member 3 gamma
chr3_+_2591331 10.77 ENSRNOT00000017466
suppressor APC domain containing 2
chr18_-_55891710 10.71 ENSRNOT00000064686
synaptopodin
chr13_-_91735361 10.67 ENSRNOT00000058090
Fc fragment of IgE receptor Ia
chr5_-_168734296 10.50 ENSRNOT00000066120
calmodulin binding transcription activator 1
chr16_-_29936307 10.50 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr3_+_20303979 10.50 ENSRNOT00000058331

chr11_+_24266345 10.47 ENSRNOT00000046973
junctional adhesion molecule 2
chr4_+_29535852 10.43 ENSRNOT00000087619
collagen, type I, alpha 2
chr8_+_100260049 10.40 ENSRNOT00000011090

chr8_-_49280901 10.22 ENSRNOT00000021390
CD3g molecule
chr16_+_2537248 10.18 ENSRNOT00000017995
ankyrin repeat and SOCS box-containing 14
chr2_-_147392062 10.18 ENSRNOT00000021535
transmembrane 4 L six family member 1
chr15_-_93765498 10.15 ENSRNOT00000093297
MYC binding protein 2, E3 ubiquitin protein ligase
chr12_-_40590361 10.11 ENSRNOT00000067503
transmembrane protein 116
chr18_-_61057365 10.07 ENSRNOT00000042352
alpha-kinase 2
chr10_-_88266210 9.99 ENSRNOT00000090702
ENSRNOT00000020603
huntingtin-associated protein 1
chrX_+_84064427 9.97 ENSRNOT00000046364
zinc finger protein 711
chr18_-_3676188 9.88 ENSRNOT00000073811
ankyrin repeat domain 29
chr6_-_108920767 9.87 ENSRNOT00000006704
prospero homeobox 2
chr8_-_84835060 9.82 ENSRNOT00000007867
leucine rich repeat containing 1
chr2_+_145174876 9.52 ENSRNOT00000040631
mab-21 like 1
chr17_+_32973695 9.51 ENSRNOT00000065674
similar to OTTMUSP00000000621
chr10_-_51778939 9.48 ENSRNOT00000078675
ENSRNOT00000057562
myocardin
chr8_+_2604962 9.47 ENSRNOT00000009993
caspase 1
chr5_-_7941822 9.47 ENSRNOT00000079917
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr14_-_115052450 9.46 ENSRNOT00000067998
acylphosphatase 2
chr4_+_88184956 9.40 ENSRNOT00000077129
vomeronasal 1 receptor 83
chr5_+_152680407 9.32 ENSRNOT00000076864
stathmin 1
chr13_-_50916982 9.11 ENSRNOT00000004408
BTG anti-proliferation factor 2
chr4_+_101687327 9.10 ENSRNOT00000082501

chr7_+_144865608 9.03 ENSRNOT00000091596
ENSRNOT00000055285
heterogeneous nuclear ribonucleoprotein A1
chr14_+_113867209 8.92 ENSRNOT00000067591
coiled coil domain containing 88A
chr11_-_17684903 8.66 ENSRNOT00000051213
transmembrane protease, serine 15
chr18_+_3887419 8.64 ENSRNOT00000093089
laminin subunit alpha 3
chr1_+_15834779 8.58 ENSRNOT00000079069
ENSRNOT00000083012
BCL2-associated transcription factor 1
chr17_-_87826421 8.56 ENSRNOT00000068156
Rho GTPase activating protein 21
chr5_-_134927235 8.46 ENSRNOT00000016751
ubiquinol-cytochrome c reductase hinge protein
chrX_+_96863891 8.43 ENSRNOT00000085665

chr12_+_41486076 8.37 ENSRNOT00000057242
RBPJ interacting and tubulin associated 1
chr10_-_67401836 8.37 ENSRNOT00000073071
cytokine receptor-like factor 3
chr8_-_39460844 8.36 ENSRNOT00000048875
PBX/knotted 1 homeobox 2
chr1_-_267463694 8.20 ENSRNOT00000084851
ENSRNOT00000016645
collagen type XVII alpha 1 chain
chr20_-_5020150 8.16 ENSRNOT00000001146
suppressor APC domain containing 1
chr3_+_17889972 8.14 ENSRNOT00000073021

chr9_+_64745051 8.11 ENSRNOT00000021527
spermatogenesis associated, serine-rich 2-like
chr2_-_191294374 8.04 ENSRNOT00000067469
similar to S100 calcium-binding protein, ventral prostate
chr5_-_22765429 7.99 ENSRNOT00000079432
aspartate-beta-hydroxylase
chrX_-_77675487 7.98 ENSRNOT00000042799
cysteinyl leukotriene receptor 1
chrX_+_40460047 7.94 ENSRNOT00000010970
phosphate regulating endopeptidase homolog, X-linked
chr6_-_51498337 7.90 ENSRNOT00000012487
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr4_+_169161585 7.83 ENSRNOT00000079785
epithelial membrane protein 1
chr6_-_108076186 7.79 ENSRNOT00000014814
family with sequence similarity 161, member B
chr6_+_76349362 7.74 ENSRNOT00000043224
aldolase 1 A retrogene 2
chr11_+_36851038 7.70 ENSRNOT00000002221
ENSRNOT00000061047
Purkinje cell protein 4
chr3_+_11763706 7.69 ENSRNOT00000078366
SH2 domain containing 3C
chr14_-_34561696 7.55 ENSRNOT00000059763
steroid 5 alpha-reductase 3
chr1_-_17378047 7.53 ENSRNOT00000020102
thymocyte selection associated
chr5_-_22769907 7.52 ENSRNOT00000047805
ENSRNOT00000076167
ENSRNOT00000076507
ENSRNOT00000076113
ENSRNOT00000083779
aspartate-beta-hydroxylase
chr7_+_15785410 7.51 ENSRNOT00000082664
ENSRNOT00000073235
zinc finger protein 955A
chr18_+_30890869 7.40 ENSRNOT00000060466
protocadherin gamma subfamily B, 6
chr10_-_105668593 7.33 ENSRNOT00000016622
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr4_+_169147243 7.25 ENSRNOT00000011580
epithelial membrane protein 1
chr12_-_23727535 7.23 ENSRNOT00000085911
ENSRNOT00000001950
deltex E3 ubiquitin ligase 2
chr5_+_165724027 7.18 ENSRNOT00000018000
castor zinc finger 1
chr4_-_163463718 7.12 ENSRNOT00000085671
killer cell lectin like receptor C1
chr1_+_101554642 7.07 ENSRNOT00000028474
branched chain amino acid transaminase 2
chr4_+_31229913 7.06 ENSRNOT00000077134
ENSRNOT00000087897
sterile alpha motif domain containing 9-like
chr10_-_74679858 7.05 ENSRNOT00000003859
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr6_+_95205153 6.99 ENSRNOT00000007339
leucine rich repeat containing 9
chr17_+_44794130 6.99 ENSRNOT00000077571
histone cluster 1, H2ac
chr10_-_89130339 6.98 ENSRNOT00000027640
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr20_+_3246739 6.92 ENSRNOT00000061299
RT1 class I, locus T24, gene 2
chr10_+_46722109 6.85 ENSRNOT00000032685
dynein regulatory complex subunit 3
chr17_-_54714914 6.83 ENSRNOT00000024336
zinc finger E-box binding homeobox 1
chr7_+_2752680 6.80 ENSRNOT00000033726
citrate synthase
chrX_+_131381134 6.79 ENSRNOT00000007474

chr2_+_266315036 6.78 ENSRNOT00000055245
wntless Wnt ligand secretion mediator
chr8_-_21492801 6.77 ENSRNOT00000077465
zinc finger protein 426
chr9_+_71915421 6.75 ENSRNOT00000020447
phosphoinositide kinase, FYVE-type zinc finger containing
chr4_+_69386698 6.67 ENSRNOT00000091655
T cell receptor beta, variable 13-2
chr6_-_21112734 6.58 ENSRNOT00000079819
RAS guanyl releasing protein 3
chrY_+_506149 6.52 ENSRNOT00000086056
lysine demethylase 5D
chr6_+_91532467 6.51 ENSRNOT00000082500
ENSRNOT00000064668
kelch domain containing 1
chr17_-_86657473 6.48 ENSRNOT00000078827

chrX_+_78042859 6.48 ENSRNOT00000003286
lysophosphatidic acid receptor 4
chr9_-_78368777 6.46 ENSRNOT00000020414
BRCA1 associated RING domain 1
chr2_-_170301348 6.45 ENSRNOT00000088131
sucrase-isomaltase
chr8_-_18762922 6.41 ENSRNOT00000008423
olfactory receptor 1122
chr1_-_63684189 6.41 ENSRNOT00000085651
leukocyte immunoglobulin-like receptor, subfamily C, member 2
chr17_-_15519282 6.32 ENSRNOT00000093577
asporin-like 1
chr20_-_10013190 6.24 ENSRNOT00000084726
ENSRNOT00000089112
radial spoke head 1 homolog
chr12_+_47590154 6.21 ENSRNOT00000045946
GIT ArfGAP 2
chr2_-_182846061 6.21 ENSRNOT00000013025
toll-like receptor 2
chrX_-_121731543 6.21 ENSRNOT00000018788
kelch-like family member 13
chr10_-_896938 6.20 ENSRNOT00000086392
nudE neurodevelopment protein 1
chr17_-_43776460 6.19 ENSRNOT00000089055
histone cluster 2, H3c2
chr15_+_4240203 6.12 ENSRNOT00000010178
MSS51 mitochondrial translational activator
chr1_+_227892956 6.08 ENSRNOT00000028483

chr5_-_162751128 6.04 ENSRNOT00000068281
similar to novel protein similar to esterases
chr2_+_57276919 6.04 ENSRNOT00000063899
similar to hypothetical protein FLJ13231
chr7_-_15073052 6.01 ENSRNOT00000037708
zinc finger protein 799
chr20_+_42966140 5.85 ENSRNOT00000000707
myristoylated alanine rich protein kinase C substrate
chr18_+_68408890 5.81 ENSRNOT00000039702
coiled-coil domain containing 68
chr16_+_84465656 5.79 ENSRNOT00000043188
LRRGT00175
chr14_+_7171613 5.78 ENSRNOT00000081600
kelch-like family member 8
chr10_+_64174931 5.76 ENSRNOT00000035948
RGD1565611
chr5_+_165465095 5.75 ENSRNOT00000031978
hypothetical protein LOC691354
chr14_+_82769642 5.74 ENSRNOT00000065393
C-terminal binding protein 1
chr10_-_104075777 5.73 ENSRNOT00000004862
hematological and neurological expressed 1
chr4_+_98481520 5.71 ENSRNOT00000078381
ENSRNOT00000048493

chr13_-_44540516 5.71 ENSRNOT00000005244
mitogen-activated protein kinase kinase kinase 19
chr16_-_18643309 5.69 ENSRNOT00000031680
DPY30 domain containing 2
chr15_-_88670349 5.64 ENSRNOT00000012881
ring finger protein 219
chr18_+_55466373 5.60 ENSRNOT00000074629
interferon-inducible GTPase 1-like
chr8_-_17525906 5.57 ENSRNOT00000007855
N-acetylated alpha-linked acidic dipeptidase 2
chr5_-_99033107 5.57 ENSRNOT00000041306
heat shock protein family A (Hsp70) member 8
chr7_-_5818625 5.55 ENSRNOT00000051699
olfactory receptor 886
chr2_-_158156150 5.53 ENSRNOT00000016621
ventricular zone expressed PH domain-containing 1
chr16_-_3765917 5.52 ENSRNOT00000088284
double homeobox B-like 1
chr20_+_3155652 5.50 ENSRNOT00000042882
RT1 class Ib, locus S2
chr7_-_83670356 5.48 ENSRNOT00000005584
syntabulin
chr6_-_143702033 5.48 ENSRNOT00000051410

chr3_+_7884822 5.46 ENSRNOT00000019157
mediator complex subunit 27
chr18_+_30036887 5.42 ENSRNOT00000077824
protocadherin alpha 4
chr17_-_15519060 5.34 ENSRNOT00000093624
asporin-like 1
chr18_+_29987206 5.33 ENSRNOT00000027383
protocadherin alpha 4
chr17_-_52477575 5.30 ENSRNOT00000081290
GLI family zinc finger 3
chr2_+_202200797 5.28 ENSRNOT00000042263
ENSRNOT00000071938
sperm associated antigen 17
chr6_-_140880070 5.27 ENSRNOT00000073779
uncharacterized LOC691828
chr3_-_16441030 5.25 ENSRNOT00000047784

chr9_-_30844199 5.25 ENSRNOT00000017169
collagen type XIX alpha 1 chain
chr3_-_71798531 5.24 ENSRNOT00000088170
calcitonin receptor like receptor
chr3_+_93909156 5.23 ENSRNOT00000090365
LIM domain only 2
chr4_-_119327822 5.20 ENSRNOT00000012645
Rho GTPase activating protein 25
chr1_+_229416489 5.20 ENSRNOT00000028617
olfactory receptor 336
chr15_-_93868292 5.16 ENSRNOT00000093546
ENSRNOT00000014583
MYC binding protein 2, E3 ubiquitin protein ligase
chr1_+_74251167 5.16 ENSRNOT00000040441
vomeronasal 2 receptor, 29
chr4_+_102489916 5.10 ENSRNOT00000082031

chr4_-_119131202 5.08 ENSRNOT00000011675
anthrax toxin receptor 1
chrX_+_14019961 5.07 ENSRNOT00000004785
synaptotagmin-like 5
chr3_+_44025300 5.06 ENSRNOT00000006319
polypeptide N-acetylgalactosaminyltransferase 5
chr16_-_28716885 5.05 ENSRNOT00000059750
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3
chr7_-_107223047 5.04 ENSRNOT00000007250
ENSRNOT00000084875
leucine rich repeat containing 6
chr13_+_6679368 5.04 ENSRNOT00000067198
ENSRNOT00000092965
contactin associated protein-like 5C
chr13_+_27312498 5.04 ENSRNOT00000003466
serpin family B member 7
chr2_+_86891092 5.02 ENSRNOT00000077162
ENSRNOT00000083066
zinc finger protein 457-like
chr1_+_252409268 5.01 ENSRNOT00000026219
lipase, family member M
chr13_-_27192592 5.00 ENSRNOT00000040021
serpin family B member 3
chr4_+_156253079 4.98 ENSRNOT00000013536
C-type lectin domain family 4, member D
chr2_+_187447501 4.95 ENSRNOT00000038589
IQ motif containing GTPase activating protein 3
chr10_-_110232843 4.92 ENSRNOT00000054934
Cd7 molecule
chr1_-_66237501 4.88 ENSRNOT00000073006
zinc finger protein 606
chr10_-_55560422 4.80 ENSRNOT00000006883
RAN guanine nucleotide release factor
chr1_-_67065797 4.79 ENSRNOT00000048152
vomeronasal 1 receptor 46
chrX_+_110016995 4.77 ENSRNOT00000093542
Nik related kinase
chrX_+_29504349 4.73 ENSRNOT00000005981
transcription elongation factor A N-terminal and central domain containing

Network of associatons between targets according to the STRING database.

First level regulatory network of Alx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.9 44.6 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
7.9 23.7 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
5.9 17.8 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
5.2 20.9 GO:2001288 detection of muscle stretch(GO:0035995) positive regulation of caveolin-mediated endocytosis(GO:2001288)
5.2 31.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
4.6 13.7 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
4.5 17.9 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
3.7 29.5 GO:0015884 folic acid transport(GO:0015884)
3.6 10.7 GO:0045399 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
3.3 10.0 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
3.2 9.5 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
3.1 3.1 GO:0032672 regulation of interleukin-3 production(GO:0032672)
3.1 15.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
3.0 14.9 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
3.0 8.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
2.8 22.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
2.7 10.7 GO:0098886 modification of dendritic spine(GO:0098886)
2.6 7.9 GO:1904383 response to sodium phosphate(GO:1904383)
2.5 12.7 GO:0060005 vestibular reflex(GO:0060005)
2.5 7.5 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
2.4 7.2 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
2.4 9.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
2.4 7.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
2.3 9.3 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
2.3 6.8 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
2.3 9.0 GO:1903936 cellular response to sodium arsenite(GO:1903936)
2.1 8.6 GO:0051684 maintenance of Golgi location(GO:0051684)
2.0 7.9 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
2.0 9.9 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
1.9 7.7 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
1.9 5.8 GO:0016598 protein arginylation(GO:0016598)
1.9 5.6 GO:0097213 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214)
1.7 5.0 GO:0035425 autocrine signaling(GO:0035425)
1.5 4.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.5 4.5 GO:2000771 epidermal stem cell homeostasis(GO:0036334) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771)
1.5 8.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
1.4 5.7 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.4 12.8 GO:0070417 cellular response to cold(GO:0070417)
1.3 4.0 GO:0000105 histidine biosynthetic process(GO:0000105)
1.3 8.0 GO:0061737 leukotriene signaling pathway(GO:0061737)
1.3 5.3 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
1.3 5.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.3 11.7 GO:0070543 response to linoleic acid(GO:0070543)
1.3 5.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.2 6.2 GO:2000574 regulation of microtubule motor activity(GO:2000574)
1.2 3.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.2 15.0 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
1.1 3.4 GO:0045799 MAPK import into nucleus(GO:0000189) regulation of chromatin assembly(GO:0010847) positive regulation of chromatin assembly or disassembly(GO:0045799)
1.1 4.5 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
1.1 5.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
1.1 17.8 GO:0032060 bleb assembly(GO:0032060)
1.1 3.2 GO:0072720 response to dithiothreitol(GO:0072720)
1.1 7.6 GO:0019348 dolichol metabolic process(GO:0019348)
1.0 4.2 GO:1903015 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) regulation of exo-alpha-sialidase activity(GO:1903015)
1.0 3.1 GO:1902211 regulation of prolactin signaling pathway(GO:1902211)
1.0 5.1 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
1.0 10.8 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
1.0 5.9 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.9 2.8 GO:0043474 eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) rhodopsin metabolic process(GO:0046154)
0.9 4.6 GO:0035617 stress granule disassembly(GO:0035617)
0.9 10.8 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.9 16.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.9 22.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.9 2.6 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.9 6.0 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.9 19.6 GO:0097435 fibril organization(GO:0097435)
0.9 2.6 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.8 10.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.8 2.5 GO:0019086 late viral transcription(GO:0019086)
0.8 4.0 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.8 16.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.8 4.8 GO:0060723 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.8 11.1 GO:0015816 glycine transport(GO:0015816)
0.8 4.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.8 2.3 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.8 1.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.8 9.1 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.8 6.8 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.7 7.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.7 7.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.7 4.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189) tetrahydrofolate biosynthetic process(GO:0046654)
0.7 2.8 GO:0030576 Cajal body organization(GO:0030576)
0.7 7.0 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.7 2.7 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.7 3.3 GO:0061709 reticulophagy(GO:0061709)
0.6 2.5 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.6 16.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.6 4.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.6 7.2 GO:0006108 malate metabolic process(GO:0006108)
0.6 4.8 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.6 6.5 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.6 4.6 GO:0060591 chondroblast differentiation(GO:0060591)
0.6 2.9 GO:0097168 mesenchymal stem cell proliferation(GO:0097168)
0.6 5.0 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.6 2.2 GO:0072709 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 3.8 GO:0048496 maintenance of organ identity(GO:0048496)
0.5 2.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.5 6.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.5 3.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.5 4.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 1.5 GO:0071245 cellular response to carbon monoxide(GO:0071245) cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033)
0.5 6.8 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.5 1.9 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.5 4.3 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.5 1.4 GO:2000464 positive regulation of astrocyte chemotaxis(GO:2000464)
0.5 1.9 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.5 3.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.5 3.8 GO:0016198 axon choice point recognition(GO:0016198)
0.5 1.9 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.5 2.8 GO:0001842 neural fold formation(GO:0001842)
0.4 3.6 GO:0033504 floor plate development(GO:0033504)
0.4 3.5 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.4 1.8 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.4 7.5 GO:0043383 negative T cell selection(GO:0043383)
0.4 2.2 GO:0035063 nuclear speck organization(GO:0035063)
0.4 5.6 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.4 4.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.4 1.3 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.4 1.3 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.4 2.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.4 5.0 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.4 5.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.3 1.4 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.3 0.7 GO:0000958 mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962)
0.3 7.3 GO:0097503 sialylation(GO:0097503)
0.3 3.6 GO:0007076 mitotic chromosome condensation(GO:0007076) regulation of histone phosphorylation(GO:0033127)
0.3 3.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 1.0 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.3 0.3 GO:2000292 regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.3 11.2 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.3 5.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 1.9 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 7.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 1.5 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.3 3.2 GO:0006465 signal peptide processing(GO:0006465)
0.3 2.0 GO:0061635 regulation of protein complex stability(GO:0061635)
0.3 1.7 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.3 11.5 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.3 6.7 GO:0032288 myelin assembly(GO:0032288)
0.3 31.1 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.3 8.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.3 3.8 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.3 11.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.3 7.5 GO:0048266 behavioral response to pain(GO:0048266)
0.2 8.4 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.2 1.7 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 3.3 GO:0051764 actin crosslink formation(GO:0051764)
0.2 1.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 1.8 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 0.9 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 8.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 1.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 3.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 3.8 GO:0050716 regulation of interleukin-1 beta secretion(GO:0050706) positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.2 1.0 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.2 3.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 0.6 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.2 1.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.2 2.3 GO:0042428 serotonin metabolic process(GO:0042428)
0.2 0.4 GO:0072319 late endosomal microautophagy(GO:0061738) vesicle uncoating(GO:0072319)
0.2 1.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.2 1.5 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.2 0.9 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 4.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.2 3.5 GO:0007413 axonal fasciculation(GO:0007413)
0.2 2.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 1.4 GO:0019388 galactose catabolic process(GO:0019388)
0.2 0.7 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 10.2 GO:0070228 regulation of lymphocyte apoptotic process(GO:0070228)
0.2 1.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 3.2 GO:0002360 T cell lineage commitment(GO:0002360)
0.2 23.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 3.4 GO:0035329 hippo signaling(GO:0035329)
0.2 0.3 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.2 0.6 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 3.9 GO:0042119 neutrophil activation(GO:0042119)
0.2 1.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 4.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 4.0 GO:0009303 rRNA transcription(GO:0009303)
0.1 10.5 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 13.5 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 1.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 1.4 GO:0042048 olfactory behavior(GO:0042048)
0.1 6.1 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 5.9 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 6.2 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 8.6 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.1 2.1 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.1 1.0 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 1.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 5.3 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 3.4 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.1 7.0 GO:0006342 chromatin silencing(GO:0006342)
0.1 8.4 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 3.6 GO:0060976 coronary vasculature development(GO:0060976)
0.1 2.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.9 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.6 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 1.0 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 4.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 6.1 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.1 2.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 2.8 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 2.2 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 2.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 5.2 GO:0030198 extracellular matrix organization(GO:0030198)
0.1 1.2 GO:0048679 regulation of axon regeneration(GO:0048679)
0.1 6.2 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 1.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.5 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 1.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.9 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.1 6.8 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.1 2.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 3.2 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0 5.9 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 0.4 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.0 0.7 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 2.4 GO:0030317 sperm motility(GO:0030317)
0.0 2.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 2.4 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 6.4 GO:0051403 stress-activated MAPK cascade(GO:0051403)
0.0 0.9 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.8 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 2.6 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 3.3 GO:0071222 cellular response to lipopolysaccharide(GO:0071222)
0.0 1.6 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 3.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 5.3 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 2.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.0 GO:0007569 cell aging(GO:0007569)
0.0 1.3 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 2.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.5 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 1.0 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 1.6 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 6.8 GO:0007155 cell adhesion(GO:0007155)
0.0 5.0 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.3 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.7 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 1.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 31.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
7.4 44.6 GO:0032280 symmetric synapse(GO:0032280)
4.5 17.8 GO:0044299 C-fiber(GO:0044299)
3.6 10.7 GO:0097444 spine apparatus(GO:0097444)
3.0 9.0 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
2.6 7.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
2.2 35.2 GO:0031527 filopodium membrane(GO:0031527)
2.1 12.8 GO:0033093 Weibel-Palade body(GO:0033093)
2.1 6.2 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
1.9 13.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
1.9 5.6 GO:1990836 lysosomal matrix(GO:1990836)
1.8 34.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.8 19.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
1.6 6.5 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
1.5 4.5 GO:0060187 cell pole(GO:0060187)
1.5 5.9 GO:0044307 germinal vesicle(GO:0042585) dendritic branch(GO:0044307)
1.4 8.6 GO:0005608 laminin-3 complex(GO:0005608)
1.4 15.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
1.3 10.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.2 3.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
1.1 5.3 GO:1990716 axonemal central apparatus(GO:1990716)
1.0 4.1 GO:0097196 Shu complex(GO:0097196)
1.0 4.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.9 4.6 GO:0072534 perineuronal net(GO:0072534)
0.9 4.5 GO:0016939 kinesin II complex(GO:0016939)
0.9 4.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.8 3.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.6 3.8 GO:0002142 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.6 6.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.6 1.7 GO:1990032 parallel fiber(GO:1990032)
0.6 2.9 GO:0044306 neuron projection terminus(GO:0044306)
0.5 5.5 GO:0097433 dense body(GO:0097433)
0.5 3.2 GO:0005787 signal peptidase complex(GO:0005787)
0.5 6.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.5 7.7 GO:0005883 neurofilament(GO:0005883)
0.5 8.2 GO:0030056 hemidesmosome(GO:0030056)
0.5 6.2 GO:0072687 meiotic spindle(GO:0072687)
0.5 6.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.4 8.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.4 3.3 GO:0016272 prefoldin complex(GO:0016272)
0.4 6.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 22.2 GO:0031672 A band(GO:0031672)
0.3 4.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 25.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.3 1.0 GO:0000811 GINS complex(GO:0000811)
0.3 3.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 4.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 2.9 GO:0001939 female pronucleus(GO:0001939)
0.3 1.9 GO:0030896 checkpoint clamp complex(GO:0030896)
0.3 3.8 GO:0030008 TRAPP complex(GO:0030008)
0.3 5.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.3 14.1 GO:0016592 mediator complex(GO:0016592)
0.3 21.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.3 1.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.3 5.7 GO:0070822 Sin3-type complex(GO:0070822)
0.3 3.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.3 1.7 GO:0036128 CatSper complex(GO:0036128)
0.3 7.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 4.6 GO:0042581 specific granule(GO:0042581)
0.3 2.1 GO:0033290 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290) eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.3 9.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 1.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.3 2.9 GO:0035253 ciliary rootlet(GO:0035253)
0.3 2.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 1.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 1.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 4.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 4.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.3 1.5 GO:0071547 piP-body(GO:0071547)
0.2 12.7 GO:0045171 intercellular bridge(GO:0045171)
0.2 7.9 GO:0002102 podosome(GO:0002102)
0.2 0.7 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 6.8 GO:0035869 ciliary transition zone(GO:0035869)
0.2 1.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 0.7 GO:0045025 mitochondrial degradosome(GO:0045025)
0.2 23.6 GO:0016605 PML body(GO:0016605)
0.2 1.6 GO:0000243 commitment complex(GO:0000243)
0.2 7.5 GO:0008180 COP9 signalosome(GO:0008180)
0.2 22.5 GO:0005814 centriole(GO:0005814)
0.2 14.3 GO:0005581 collagen trimer(GO:0005581)
0.2 1.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 2.8 GO:0044292 dendrite terminus(GO:0044292)
0.2 1.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 3.1 GO:0001772 immunological synapse(GO:0001772)
0.1 2.7 GO:0097546 ciliary base(GO:0097546)
0.1 3.3 GO:0031941 filamentous actin(GO:0031941)
0.1 9.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 6.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 7.0 GO:0000786 nucleosome(GO:0000786)
0.1 4.8 GO:0014704 intercalated disc(GO:0014704)
0.1 18.4 GO:0030427 site of polarized growth(GO:0030427)
0.1 5.2 GO:0015030 Cajal body(GO:0015030)
0.1 3.1 GO:0030286 dynein complex(GO:0030286)
0.1 5.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 7.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.3 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 6.8 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 0.3 GO:0070820 tertiary granule(GO:0070820)
0.1 23.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.4 GO:0090543 Flemming body(GO:0090543)
0.1 0.9 GO:0010369 chromocenter(GO:0010369)
0.1 1.3 GO:0097449 astrocyte projection(GO:0097449)
0.1 4.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 5.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 10.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.3 GO:0035861 site of double-strand break(GO:0035861)
0.1 19.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 3.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 9.5 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.1 2.6 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.1 14.1 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 15.6 GO:0031965 nuclear membrane(GO:0031965)
0.1 29.0 GO:0045202 synapse(GO:0045202)
0.1 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 2.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 31.1 GO:0005730 nucleolus(GO:0005730)
0.0 18.0 GO:0030424 axon(GO:0030424)
0.0 8.7 GO:0000785 chromatin(GO:0000785)
0.0 0.4 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.8 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 1.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 4.8 GO:0016604 nuclear body(GO:0016604)
0.0 1.7 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 23.7 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
7.8 31.1 GO:0019002 GMP binding(GO:0019002)
7.4 44.6 GO:0001515 opioid peptide activity(GO:0001515)
3.7 14.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
3.7 29.5 GO:0008517 folic acid transporter activity(GO:0008517)
3.2 19.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
3.0 23.8 GO:0071253 connexin binding(GO:0071253)
2.6 10.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
2.4 7.1 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
2.1 6.2 GO:0042498 diacyl lipopeptide binding(GO:0042498)
2.0 10.0 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
2.0 35.9 GO:0005523 tropomyosin binding(GO:0005523)
1.9 7.6 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
1.8 10.7 GO:0019767 IgE receptor activity(GO:0019767)
1.7 5.2 GO:0001605 adrenomedullin receptor activity(GO:0001605)
1.6 4.9 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
1.6 8.0 GO:0004974 leukotriene receptor activity(GO:0004974)
1.5 4.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
1.4 4.3 GO:0016882 cyclo-ligase activity(GO:0016882)
1.4 5.6 GO:0031686 A1 adenosine receptor binding(GO:0031686)
1.4 6.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.4 2.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.2 4.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.1 7.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.1 7.7 GO:0033592 RNA strand annealing activity(GO:0033592)
1.0 16.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.0 4.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.0 7.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.0 5.0 GO:0032027 myosin light chain binding(GO:0032027)
1.0 6.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.9 4.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.9 3.5 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.9 2.6 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.9 4.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.9 4.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.9 11.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.8 22.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.8 6.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.8 6.7 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.7 9.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.7 5.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.7 7.2 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.6 2.6 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.6 1.9 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.6 4.2 GO:0001849 complement component C1q binding(GO:0001849)
0.6 7.1 GO:1990405 protein antigen binding(GO:1990405)
0.6 7.6 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.5 7.9 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.5 1.5 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.5 11.7 GO:0051861 glycolipid binding(GO:0051861)
0.5 11.7 GO:0015288 porin activity(GO:0015288)
0.5 11.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.5 3.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.5 8.9 GO:0043422 protein kinase B binding(GO:0043422)
0.5 3.9 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.5 2.8 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.5 5.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4 12.7 GO:0003785 actin monomer binding(GO:0003785)
0.4 9.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.4 9.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.4 5.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 3.4 GO:0043495 protein anchor(GO:0043495)
0.4 3.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.4 1.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.4 1.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.4 1.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.4 15.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.4 42.1 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.3 4.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 33.9 GO:0016503 pheromone receptor activity(GO:0016503)
0.3 7.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.3 3.8 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.3 7.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 1.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.3 1.4 GO:0005042 netrin receptor activity(GO:0005042)
0.3 3.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.3 5.0 GO:0001618 virus receptor activity(GO:0001618)
0.3 1.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 2.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 1.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 5.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 15.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.2 2.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 3.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 8.6 GO:0070888 E-box binding(GO:0070888)
0.2 1.3 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.2 0.6 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 2.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 12.9 GO:0019894 kinesin binding(GO:0019894)
0.2 6.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 1.0 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 1.0 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 8.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 1.1 GO:0045503 dynein light chain binding(GO:0045503)
0.2 2.7 GO:0051400 BH domain binding(GO:0051400)
0.2 4.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 4.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 0.9 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.1 6.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 17.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 3.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 5.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 9.6 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 39.6 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 6.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.6 GO:0032183 SUMO binding(GO:0032183)
0.1 1.9 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 2.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 8.8 GO:0005518 collagen binding(GO:0005518)
0.1 3.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 3.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 2.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 6.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 1.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 2.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 4.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 3.1 GO:0004532 exoribonuclease activity(GO:0004532)
0.1 37.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 1.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 7.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 26.9 GO:0003779 actin binding(GO:0003779)
0.1 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 23.8 GO:0005525 GTP binding(GO:0005525)
0.1 0.6 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.3 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 1.6 GO:0017069 snRNA binding(GO:0017069)
0.1 3.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.9 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 2.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 2.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 2.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 2.1 GO:0003823 antigen binding(GO:0003823)
0.0 7.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 2.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 5.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 14.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.7 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 5.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.3 GO:0004540 ribonuclease activity(GO:0004540)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.2 GO:0005496 steroid binding(GO:0005496)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 1.2 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 16.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.9 20.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.8 9.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.8 11.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.8 64.2 PID AP1 PATHWAY AP-1 transcription factor network
0.5 8.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 16.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.4 8.0 PID ENDOTHELIN PATHWAY Endothelins
0.4 25.8 PID NOTCH PATHWAY Notch signaling pathway
0.4 11.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.4 6.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.4 10.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 7.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.3 8.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.3 10.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 11.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.3 8.3 PID RAS PATHWAY Regulation of Ras family activation
0.2 9.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 5.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 3.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 6.8 PID BARD1 PATHWAY BARD1 signaling events
0.2 3.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 7.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 6.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 8.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 5.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 3.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 26.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 2.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 3.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 4.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 9.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 2.7 PID IL27 PATHWAY IL27-mediated signaling events
0.1 9.8 PID CMYB PATHWAY C-MYB transcription factor network
0.1 3.6 PID ATM PATHWAY ATM pathway
0.1 4.8 PID TNF PATHWAY TNF receptor signaling pathway
0.1 4.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 8.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 6.0 NABA COLLAGENS Genes encoding collagen proteins
0.1 4.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 2.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 2.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.0 ST ADRENERGIC Adrenergic Pathway
0.1 2.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 3.4 PID LKB1 PATHWAY LKB1 signaling events
0.1 13.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.9 PID AURORA B PATHWAY Aurora B signaling
0.1 3.9 PID E2F PATHWAY E2F transcription factor network
0.1 1.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
1.3 10.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.9 15.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.8 4.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.8 9.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.7 9.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.6 6.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.6 6.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.6 5.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.6 8.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.5 31.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.5 11.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.5 6.0 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.5 18.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.5 21.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 6.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.4 4.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 3.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 8.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 4.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 7.9 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.3 4.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 4.6 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2 7.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 14.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 1.9 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.2 5.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 9.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 3.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 4.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2 10.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 4.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2 2.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 3.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 3.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 1.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 2.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 3.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 5.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.2 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.1 8.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.9 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 16.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 2.0 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 3.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 3.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 8.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 5.8 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.1 8.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.9 REACTOME KINESINS Genes involved in Kinesins
0.1 1.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.6 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 9.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 7.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 1.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 3.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 6.8 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1 8.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 4.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 1.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 6.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)