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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Zkscan1
Z-value: 0.43
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Transcription factors associated with Zkscan1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zkscan1 | rn6_v1_chr12_+_19231092_19231092 | 0.26 | 6.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_47987255 Show fit | 1.41 |
ENSRNOT00000074000
|
ubiquitin protein ligase E3B |
|
| chr14_+_1462358 Show fit | 0.31 |
ENSRNOT00000077243
|
colony stimulating factor 2 receptor alpha subunit |
|
| chr2_-_187742747 Show fit | 0.25 |
ENSRNOT00000026530
|
bone gamma-carboxyglutamate protein |
|
| chr2_+_198772937 Show fit | 0.18 |
ENSRNOT00000028812
|
integrin subunit alpha 10 |
|
| chr7_-_119896925 Show fit | 0.14 |
ENSRNOT00000010609
|
extracellular leucine-rich repeat and fibronectin type III domain containing 2 |
|
| chr10_+_71278650 Show fit | 0.11 |
ENSRNOT00000092020
|
synergin, gamma |
|
| chr8_+_116804451 Show fit | 0.11 |
ENSRNOT00000041402
|
inositol hexakisphosphate kinase 1 |
|
| chr2_+_22427474 Show fit | 0.10 |
ENSRNOT00000061761
|
metaxin 3 |
|
| chrX_+_31140960 Show fit | 0.08 |
ENSRNOT00000084395
ENSRNOT00000004494 |
motile sperm domain containing 2 |
|
| chr7_-_123638702 Show fit | 0.08 |
ENSRNOT00000082473
ENSRNOT00000044470 ENSRNOT00000092017 |
cytochrome P450, family 2, subfamily d, polypeptide 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Zkscan1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0038158 | granulocyte colony-stimulating factor signaling pathway(GO:0038158) |
| 0.0 | 0.3 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.0 | 0.1 | GO:1905217 | response to astaxanthin(GO:1905217) cellular response to astaxanthin(GO:1905218) |
| 0.0 | 0.1 | GO:0021918 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937) |
| 0.0 | 0.1 | GO:1904844 | regulation of renal output by angiotensin(GO:0002019) response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 0.0 | 0.1 | GO:0032701 | negative regulation of interleukin-18 production(GO:0032701) |
| 0.0 | 0.1 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0032044 | DSIF complex(GO:0032044) |
| 0.0 | 0.1 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.0 | 0.1 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0051916 | granulocyte colony-stimulating factor binding(GO:0051916) |
| 0.0 | 0.2 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.0 | 0.1 | GO:0052723 | inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.0 | 0.1 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.0 | 0.1 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.0 | 0.1 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 0.0 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.0 | 0.0 | GO:0004781 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
| 0.0 | 0.0 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.0 | 0.0 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |