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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Zkscan1

Z-value: 0.43

Motif logo

Transcription factors associated with Zkscan1

Gene Symbol Gene ID Gene Info
ENSRNOG00000001335 zinc finger with KRAB and SCAN domains 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zkscan1rn6_v1_chr12_+_19231092_192310920.266.7e-01Click!

Activity profile of Zkscan1 motif

Sorted Z-values of Zkscan1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_47987255 1.41 ENSRNOT00000074000
ubiquitin protein ligase E3B
chr14_+_1462358 0.31 ENSRNOT00000077243
colony stimulating factor 2 receptor alpha subunit
chr2_-_187742747 0.25 ENSRNOT00000026530
bone gamma-carboxyglutamate protein
chr2_+_198772937 0.18 ENSRNOT00000028812
integrin subunit alpha 10
chr7_-_119896925 0.14 ENSRNOT00000010609
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr10_+_71278650 0.11 ENSRNOT00000092020
synergin, gamma
chr8_+_116804451 0.11 ENSRNOT00000041402
inositol hexakisphosphate kinase 1
chr2_+_22427474 0.10 ENSRNOT00000061761
metaxin 3
chrX_+_31140960 0.08 ENSRNOT00000084395
ENSRNOT00000004494
motile sperm domain containing 2
chr7_-_123638702 0.08 ENSRNOT00000082473
ENSRNOT00000044470
ENSRNOT00000092017
cytochrome P450, family 2, subfamily d, polypeptide 1
chr7_-_123767797 0.08 ENSRNOT00000012699
transcription factor 20
chr8_-_115358046 0.08 ENSRNOT00000017607
glutamate metabotropic receptor 2
chr5_-_74366817 0.07 ENSRNOT00000076705
protein tyrosine phosphatase, non-receptor type 3
chr9_+_98668231 0.07 ENSRNOT00000027528
ankyrin repeat and SOCS box-containing 1
chr1_-_228755866 0.07 ENSRNOT00000083283
deltex E3 ubiquitin ligase 4
chr3_-_10226286 0.07 ENSRNOT00000093627
far upstream element binding protein 3
chr17_-_10818835 0.07 ENSRNOT00000091046
complexin 2
chr3_+_95715193 0.07 ENSRNOT00000089525
paired box 6
chr4_+_57378069 0.07 ENSRNOT00000080173
ENSRNOT00000011851
nuclear respiratory factor 1
chr13_+_90244681 0.06 ENSRNOT00000078162
CD84 molecule
chr7_+_13039781 0.06 ENSRNOT00000067771
ENSRNOT00000090048
mesoderm induction early response 1, family member 2
chr12_-_52644260 0.06 ENSRNOT00000073986
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr1_+_203971152 0.06 ENSRNOT00000075540
G protein-coupled receptor 26
chr17_+_20619324 0.06 ENSRNOT00000079788

chr17_+_70684539 0.06 ENSRNOT00000025700
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_+_85438105 0.06 ENSRNOT00000048905
SPT5 homolog, DSIF elongation factor subunit
chr7_-_118840634 0.06 ENSRNOT00000031568
apolipoprotein L 11a
chr19_-_55257876 0.05 ENSRNOT00000017564
cytochrome b-245 alpha chain
chr9_+_10305470 0.05 ENSRNOT00000072592
neurturin
chr1_+_219000844 0.05 ENSRNOT00000022486
lysine methyltransferase 5B
chr16_+_71738718 0.05 ENSRNOT00000022097
pleckstrin homology domain containing A2
chr7_-_141001993 0.05 ENSRNOT00000092068
formin-like 3
chr16_-_6404957 0.05 ENSRNOT00000048459
calcium voltage-gated channel subunit alpha1 D
chr5_-_159602251 0.05 ENSRNOT00000011394
NECAP endocytosis associated 2
chr6_-_3254779 0.05 ENSRNOT00000061975
cyclin-dependent kinase-like 4
chr14_+_113202419 0.05 ENSRNOT00000004764
EGF-containing fibulin-like extracellular matrix protein 1
chr5_-_137112927 0.05 ENSRNOT00000078302
protein tyrosine phosphatase, receptor type, F
chr7_-_119797098 0.05 ENSRNOT00000009994
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr7_-_12673659 0.05 ENSRNOT00000091650
ENSRNOT00000041277
ENSRNOT00000044865
polypyrimidine tract binding protein 1
chr3_-_80875817 0.04 ENSRNOT00000091265
diacylglycerol kinase zeta
chr1_+_251145253 0.04 ENSRNOT00000083555
ENSRNOT00000014979
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr6_+_26390689 0.04 ENSRNOT00000079762
ENSRNOT00000091528
intraflagellar transport 172
chr6_-_126582034 0.04 ENSRNOT00000010656
ENSRNOT00000080829
inositol-tetrakisphosphate 1-kinase
chr3_+_100787956 0.04 ENSRNOT00000073636
brain-derived neurotrophic factor
chr3_-_148312791 0.04 ENSRNOT00000091419
Bcl2-like 1
chr17_+_15966234 0.04 ENSRNOT00000084304
WNK lysine deficient protein kinase 2
chr5_+_151413382 0.04 ENSRNOT00000012626
CD164 molecule like 2
chr10_-_65424802 0.04 ENSRNOT00000018468
Tnf receptor associated factor 4
chr18_-_69944632 0.04 ENSRNOT00000047271
mitogen-activated protein kinase 4
chr8_-_120446455 0.04 ENSRNOT00000085161
ENSRNOT00000042854
ENSRNOT00000037199
cAMP regulated phosphoprotein 21
chr3_+_100787449 0.04 ENSRNOT00000078543
brain-derived neurotrophic factor
chr10_+_14248399 0.03 ENSRNOT00000077689
splA/ryanodine receptor domain and SOCS box containing 3
chr1_+_61095171 0.03 ENSRNOT00000042702
vomeronasal 1 receptor 19
chr10_+_46722109 0.03 ENSRNOT00000032685
dynein regulatory complex subunit 3
chr15_-_12513931 0.03 ENSRNOT00000010103
ataxin 7
chr3_-_148312420 0.03 ENSRNOT00000047416
ENSRNOT00000081272
Bcl2-like 1
chr1_-_262014066 0.03 ENSRNOT00000087083
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chr17_+_26785029 0.03 ENSRNOT00000022065
eukaryotic translation elongation factor 1 epsilon 1
chr4_-_85915099 0.03 ENSRNOT00000016182
neuronal differentiation 6
chr6_+_108936664 0.03 ENSRNOT00000007298
dihydrolipoamide S-succinyltransferase
chr1_-_204817080 0.03 ENSRNOT00000077956
family with sequence similarity 53, member B
chr19_-_38484611 0.02 ENSRNOT00000077960
nuclear factor of activated T-cells 5
chr6_+_137184820 0.02 ENSRNOT00000073796
adenylosuccinate synthase like 1
chr17_-_55346279 0.02 ENSRNOT00000025037
supervillin
chr13_-_82753438 0.02 ENSRNOT00000075948
ATPase Na+/K+ transporting subunit beta 1
chr6_+_69971227 0.02 ENSRNOT00000075349
forkhead box G1
chr1_-_87147308 0.02 ENSRNOT00000027773
ENSRNOT00000089305
ENSRNOT00000090402
actinin alpha 4
chr14_-_45165207 0.02 ENSRNOT00000002960
Kruppel like factor 3
chr4_+_77554269 0.02 ENSRNOT00000037248
zinc finger protein 282
chr15_+_18399733 0.01 ENSRNOT00000061158
family with sequence similarity 107, member A
chr7_+_18409147 0.01 ENSRNOT00000086336
ENSRNOT00000011849
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr15_-_18695133 0.01 ENSRNOT00000012271
abhydrolase domain containing 6
chr10_-_104718621 0.01 ENSRNOT00000011560
Fas binding factor 1
chrX_-_1369384 0.01 ENSRNOT00000013745
TIMP metallopeptidase inhibitor 1
chr7_+_11545024 0.01 ENSRNOT00000073221
solute carrier family 39 member 3
chr3_-_151258580 0.01 ENSRNOT00000026120
ER degradation enhancing alpha-mannosidase like protein 2
chr11_+_82848853 0.01 ENSRNOT00000073743
thrombopoietin
chr3_+_80362858 0.01 ENSRNOT00000021353
ENSRNOT00000086242
LDL receptor related protein 4
chr8_-_62893087 0.01 ENSRNOT00000058490
coiled-coil domain containing 33
chr6_+_111642411 0.01 ENSRNOT00000016962
aarF domain containing kinase 1
chr2_-_219097619 0.01 ENSRNOT00000078806
vascular cell adhesion molecule 1
chr7_+_12798868 0.01 ENSRNOT00000038553
protease, serine, 57
chr14_-_5378726 0.01 ENSRNOT00000002896
leucine rich repeat containing 8 family, member C
chr8_+_19888667 0.01 ENSRNOT00000078593
zinc finger protein 317
chr10_-_98018014 0.01 ENSRNOT00000005367
FAM20A, golgi associated secretory pathway pseudokinase
chr6_+_136682126 0.01 ENSRNOT00000017454
asparaginase
chr5_-_153252021 0.01 ENSRNOT00000023221
transmembrane protein 50A
chr6_+_107999846 0.01 ENSRNOT00000058095
prostaglandin reductase 2
chr8_+_67295727 0.01 ENSRNOT00000020443
acidic nuclear phosphoprotein 32 family member A
chr1_-_219682287 0.01 ENSRNOT00000026092
ras homolog family member D
chr16_-_62373253 0.00 ENSRNOT00000034325
testis expressed 15, meiosis and synapsis associated
chr3_+_72134731 0.00 ENSRNOT00000083592
yippee-like 4
chr3_-_59688692 0.00 ENSRNOT00000078752
Sp3 transcription factor
chr5_-_128839433 0.00 ENSRNOT00000065280
oxysterol binding protein-like 9
chr6_-_102196138 0.00 ENSRNOT00000014132
transmembrane protein 229B
chr2_-_30577218 0.00 ENSRNOT00000024674
occludin
chr12_-_36587839 0.00 ENSRNOT00000001295
Bri3 binding protein
chr3_+_152909189 0.00 ENSRNOT00000066341
TGFB-induced factor homeobox 2
chr8_-_21995806 0.00 ENSRNOT00000028034
sphingosine-1-phosphate receptor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Zkscan1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.3 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:1905217 response to astaxanthin(GO:1905217) cellular response to astaxanthin(GO:1905218)
0.0 0.1 GO:0021918 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.0 0.1 GO:1904844 regulation of renal output by angiotensin(GO:0002019) response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0052723 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events