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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Zic3

Z-value: 0.26

Motif logo

Transcription factors associated with Zic3

Gene Symbol Gene ID Gene Info
ENSRNOG00000000861 Zic family member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zic3rn6_v1_chrX_+_140878216_140878216-0.365.5e-01Click!

Activity profile of Zic3 motif

Sorted Z-values of Zic3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_14348046 0.24 ENSRNOT00000018630
cadherin-related family member 1
chr8_+_44136496 0.09 ENSRNOT00000087022
sodium voltage-gated channel beta subunit 3
chr3_+_80833272 0.08 ENSRNOT00000023583
cholinergic receptor, muscarinic 4
chrX_+_76786466 0.08 ENSRNOT00000090665
fibroblast growth factor 16
chr18_-_28454756 0.07 ENSRNOT00000040091
spermatogenesis associated 24
chr3_-_39596718 0.07 ENSRNOT00000006784
reprimo, TP53 dependent G2 arrest mediator candidate
chr7_+_12006710 0.06 ENSRNOT00000045421
Kruppel-like factor 16
chr7_-_143967484 0.06 ENSRNOT00000081758
Sp7 transcription factor
chr6_-_95502775 0.05 ENSRNOT00000074990
ENSRNOT00000034289
dehydrogenase/reductase (SDR family) member 7-like 1
chr4_+_115416580 0.05 ENSRNOT00000018303
ATPase H+ transporting V1 subunit B1
chr7_-_61798729 0.05 ENSRNOT00000010283
dual specificity tyrosine phosphorylation regulated kinase 2
chr2_+_216863428 0.05 ENSRNOT00000068413
collagen type XI alpha 1 chain
chr19_-_11144641 0.05 ENSRNOT00000081246
solute carrier family 12 member 3
chr10_+_59566223 0.05 ENSRNOT00000024068
ENSRNOT00000088245
purinergic receptor P2X 1
chr10_+_3227160 0.05 ENSRNOT00000088075
N-terminal asparagine amidase
chr13_+_52887649 0.05 ENSRNOT00000048033
achaete-scute family bHLH transcription factor 5
chr6_+_27975417 0.05 ENSRNOT00000077830
dystrobrevin, beta
chr16_+_22979444 0.05 ENSRNOT00000017822
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr13_-_70626252 0.05 ENSRNOT00000036947
laminin subunit gamma 2
chr7_-_143966863 0.05 ENSRNOT00000018828
Sp7 transcription factor
chr17_+_43458553 0.04 ENSRNOT00000088939
solute carrier family 17, member 4
chr7_-_121311565 0.04 ENSRNOT00000092252
ribosomal protein L3
chr8_-_53362006 0.04 ENSRNOT00000077145
claudin 25-like
chr2_-_260596777 0.04 ENSRNOT00000009370
LIM homeobox 8
chr1_-_88989552 0.04 ENSRNOT00000034001
Rho GTPase activating protein 33
chr9_-_55673704 0.04 ENSRNOT00000066231
ENSRNOT00000081677
transmembrane protein with EGF-like and two follistatin-like domains 2
chr9_-_15700235 0.04 ENSRNOT00000088713
ENSRNOT00000035907
transcriptional regulating factor 1
chr10_-_90312386 0.04 ENSRNOT00000028445
solute carrier family 4 member 1
chr10_-_110585376 0.04 ENSRNOT00000054917
Rab40b, member RAS oncogene family
chr7_+_41115154 0.04 ENSRNOT00000066174
ATPase plasma membrane Ca2+ transporting 1
chr19_+_60017746 0.04 ENSRNOT00000042623
par-3 family cell polarity regulator
chr20_-_47306318 0.03 ENSRNOT00000075151
nuclear receptor subfamily 2, group E, member 1
chr3_+_100787449 0.03 ENSRNOT00000078543
brain-derived neurotrophic factor
chr10_-_87541851 0.03 ENSRNOT00000089610
similar to keratin associated protein 2-4
chr2_+_199283909 0.03 ENSRNOT00000043194
acid phosphatase 6, lysophosphatidic
chr16_+_19800463 0.03 ENSRNOT00000023065
ankyrin repeat and LEM domain containing 1
chr10_-_13580821 0.03 ENSRNOT00000009735
netrin 3
chr2_+_195582781 0.03 ENSRNOT00000066020
thioesterase superfamily member 5
chr3_-_10196626 0.03 ENSRNOT00000012234
PR/SET domain 12
chr20_-_4401610 0.03 ENSRNOT00000091468
palmitoyl-protein thioesterase 2
chr1_-_176607466 0.03 ENSRNOT00000022984
polypeptide N-acetylgalactosaminyltransferase 18
chr5_+_76182121 0.03 ENSRNOT00000020707
G protein subunit gamma 10
chr8_-_48774898 0.03 ENSRNOT00000016303
uroplakin 2
chr7_+_12764993 0.03 ENSRNOT00000017064
glutamate ionotropic receptor NMDA type subunit 3B
chr2_+_9683570 0.03 ENSRNOT00000074157
centrin 3
chr8_-_129919120 0.03 ENSRNOT00000074423
unc-51 like kinase 4
chr10_-_35005287 0.03 ENSRNOT00000032386
nedd4 binding protein 3
chr20_+_4576514 0.03 ENSRNOT00000090125
ENSRNOT00000047370
euchromatic histone lysine methyltransferase 2
chr12_+_48598647 0.03 ENSRNOT00000000889
transmembrane protein 119
chr3_+_175885894 0.03 ENSRNOT00000039780
neurotensin receptor 1
chr13_+_52624878 0.03 ENSRNOT00000076054
ENSRNOT00000076299
troponin I1, slow skeletal type
chr5_-_173653905 0.03 ENSRNOT00000038556
pleckstrin homology domain containing N1
chr3_+_5624506 0.03 ENSRNOT00000036995
ADAMTS-like 2
chr1_-_72461547 0.02 ENSRNOT00000022480
scavenger receptor cysteine rich family member with 5 domains
chr20_-_4390436 0.02 ENSRNOT00000000497
ENSRNOT00000077655
palmitoyl-protein thioesterase 2
chr3_+_111545007 0.02 ENSRNOT00000007247
inositol-trisphosphate 3-kinase A
chr1_+_81230612 0.02 ENSRNOT00000026489
potassium calcium-activated channel subfamily N member 4
chr1_-_228753422 0.02 ENSRNOT00000028626
deltex E3 ubiquitin ligase 4
chr10_+_56260514 0.02 ENSRNOT00000016177
SRY box 15
chr1_-_80744831 0.02 ENSRNOT00000025913
B-cell CLL/lymphoma 3
chr5_+_153507093 0.02 ENSRNOT00000086650
ENSRNOT00000083645
runt-related transcription factor 3
chr9_-_81566642 0.02 ENSRNOT00000080345
angio-associated, migratory cell protein
chr5_-_151895016 0.02 ENSRNOT00000081841
phosphatidylinositol glycan anchor biosynthesis, class V
chr5_+_106952082 0.02 ENSRNOT00000046931
similar to put. precursor MuIFN-alpha 5
chr2_-_130658202 0.02 ENSRNOT00000017012
poly(A) binding protein, cytoplasmic 4-like
chr10_-_14937336 0.02 ENSRNOT00000025494
SRY box 8
chr5_+_133620706 0.02 ENSRNOT00000053202
predicted gene 12830
chr17_+_82066152 0.02 ENSRNOT00000083034
ADP-ribosylation factor like GTPase 5B
chr11_+_45751812 0.02 ENSRNOT00000079336
similar to Dermal papilla derived protein 7
chr13_-_70625842 0.02 ENSRNOT00000092499
laminin subunit gamma 2
chr2_-_24923128 0.02 ENSRNOT00000044087
phosphodiesterase 8B
chrX_-_112328642 0.02 ENSRNOT00000083150
proteasome 26S subunit, non-ATPase 10
chr10_+_82937971 0.02 ENSRNOT00000005797
distal-less homeobox 3
chr3_+_110367939 0.02 ENSRNOT00000010406
BUB1 mitotic checkpoint serine/threonine kinase B
chr2_-_188553289 0.02 ENSRNOT00000088822
tripartite motif-containing 46
chr5_-_58113553 0.02 ENSRNOT00000046589
AT-rich interaction domain 3C
chr1_-_89045586 0.02 ENSRNOT00000063808
zinc finger and BTB domain containing 32
chr4_+_157513414 0.02 ENSRNOT00000078769
PILR alpha associated neural protein
chr1_+_84044551 0.02 ENSRNOT00000028290
coenzyme Q8B
chr7_-_2961873 0.02 ENSRNOT00000067441
ribosomal protein S15, pseudogene 2
chr20_+_5125679 0.02 ENSRNOT00000060832
BCL2-associated athanogene 6
chr10_+_105787935 0.02 ENSRNOT00000000266
methyltransferase like 23
chr4_+_180887182 0.02 ENSRNOT00000042270
ENSRNOT00000002476
FGFR1 oncogene partner 2
chr2_-_28003186 0.02 ENSRNOT00000048554
hexosaminidase subunit beta
chr1_-_220746224 0.02 ENSRNOT00000027734
barrier to autointegration factor 1
chr10_-_56412544 0.02 ENSRNOT00000020578
transmembrane protein 102
chr1_+_219144205 0.02 ENSRNOT00000083942
unc-93 homolog B1 (C. elegans)
chr3_-_146470293 0.02 ENSRNOT00000009627
acyl-CoA synthetase short-chain family member 1
chrX_+_28435507 0.02 ENSRNOT00000005615
phosphoribosyl pyrophosphate synthetase 2
chrX_-_18096938 0.02 ENSRNOT00000042670
spindlin-2B-like
chr10_+_65448950 0.02 ENSRNOT00000082348
ENSRNOT00000037016
RAB34, member RAS oncogene family
chr20_+_14577166 0.02 ENSRNOT00000085583
rhabdoid tumor deletion region gene 1
chr1_+_123015746 0.02 ENSRNOT00000013483
MAGE family member L2
chr5_+_140979435 0.02 ENSRNOT00000056592
poly(A) binding protein, cytoplasmic 4
chr10_+_65507364 0.01 ENSRNOT00000016297
stromal cell derived factor 2
chr1_-_72727112 0.01 ENSRNOT00000031172
BR serine/threonine kinase 1
chr20_-_11737050 0.01 ENSRNOT00000001637
small ubiquitin-like modifier 3
chr19_+_61677542 0.01 ENSRNOT00000014785
integrin subunit beta 1
chr1_+_261291870 0.01 ENSRNOT00000049914
4-hydroxy-2-oxoglutarate aldolase 1
chr4_-_180887050 0.01 ENSRNOT00000065730
integrator complex subunit 13
chr10_+_20320878 0.01 ENSRNOT00000009714
slit guidance ligand 3
chr6_+_128750795 0.01 ENSRNOT00000005781
glutaredoxin 5
chr15_-_45524582 0.01 ENSRNOT00000081912
guanylate cyclase 1 soluble subunit beta 2
chr1_+_151918571 0.01 ENSRNOT00000022342
cathepsin C
chr3_+_150055749 0.01 ENSRNOT00000055335
actin-like 10
chr10_-_58784374 0.01 ENSRNOT00000019919
mediator complex subunit 31
chr3_-_165741967 0.01 ENSRNOT00000017063
zinc finger protein 64
chr6_-_24985716 0.01 ENSRNOT00000010613
polypeptide N-acetylgalactosaminyltransferase 14
chr7_-_136853957 0.01 ENSRNOT00000008985
neural EGFL like 2
chr10_+_104019888 0.01 ENSRNOT00000032016
solute carrier family 16 member 5
chr10_-_56506446 0.01 ENSRNOT00000021357
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr7_-_120026755 0.01 ENSRNOT00000077677
caspase recruitment domain family, member 10
chr8_-_111965889 0.01 ENSRNOT00000032376
beaded filament structural protein 2
chrX_+_54734385 0.01 ENSRNOT00000005023
nuclear receptor subfamily 0, group B, member 1
chr5_-_101166651 0.01 ENSRNOT00000078862
Fras1 related extracellular matrix 1
chr8_-_97115027 0.01 ENSRNOT00000018685
ankyrin repeat domain 34C
chr1_+_282265370 0.01 ENSRNOT00000015687
G protein-coupled receptor kinase 5
chr5_-_107388182 0.01 ENSRNOT00000058358
interferon alpha-1-like
chr1_+_79899155 0.01 ENSRNOT00000078503
Myb-related transcription factor, partner of profilin
chr12_+_22835019 0.01 ENSRNOT00000059530
collagen type XXVI alpha 1 chain
chr9_-_114619711 0.01 ENSRNOT00000050012
microtubule crosslinking factor 1
chr10_+_46840113 0.01 ENSRNOT00000086083
ENSRNOT00000079133
myosin XVA
chr7_-_120027026 0.01 ENSRNOT00000011215
caspase recruitment domain family, member 10
chr1_+_101178104 0.01 ENSRNOT00000028072
parathyroid hormone 2
chr8_-_59239954 0.01 ENSRNOT00000016104
acyl-CoA synthetase bubblegum family member 1
chr1_-_219144610 0.01 ENSRNOT00000023526
NADH:ubiquinone oxidoreductase core subunit S8
chr8_+_116708027 0.01 ENSRNOT00000047309
actin-like 11
chr4_+_160168297 0.01 ENSRNOT00000083226
calcium release activated channel regulator 2A
chr6_-_24563246 0.01 ENSRNOT00000074294
hypothetical protein LOC685881
chr7_+_28066635 0.01 ENSRNOT00000005844
phenylalanine hydroxylase
chr3_-_151363115 0.01 ENSRNOT00000073492
eukaryotic translation initiation factor 6
chr4_-_67520356 0.01 ENSRNOT00000014604
B-Raf proto-oncogene, serine/threonine kinase
chr1_+_222198534 0.01 ENSRNOT00000028712
BCL2-associated agonist of cell death
chr5_+_68717519 0.01 ENSRNOT00000066226
structural maintenance of chromosomes 2
chr17_+_43460782 0.01 ENSRNOT00000059494
solute carrier family 17, member 4
chr10_-_85289777 0.01 ENSRNOT00000055427
ENSRNOT00000014863
G protein-coupled receptor 179
chr7_-_143473697 0.01 ENSRNOT00000055336
ENSRNOT00000083027
keratin 77
chr18_+_16650806 0.01 ENSRNOT00000093679
ENSRNOT00000041961
ENSRNOT00000093140
formin homology 2 domain containing 3
chr8_+_71719563 0.01 ENSRNOT00000022828
peptidylprolyl isomerase B
chr8_+_85489553 0.01 ENSRNOT00000082158
ribosomal protein L12, pseudogene 1
chr17_+_86199623 0.01 ENSRNOT00000022727
pancreas specific transcription factor, 1a
chr9_+_99998275 0.01 ENSRNOT00000074395
glypican 1
chr6_+_136380990 0.01 ENSRNOT00000063865
ENSRNOT00000082914
zinc finger FYVE-type containing 21
chr10_-_34439470 0.01 ENSRNOT00000072081
butyrophilin-like 9
chr3_-_94767239 0.01 ENSRNOT00000056808
glutamine and serine rich 1
chr17_+_8135251 0.01 ENSRNOT00000016982
transient receptor potential cation channel, subfamily C, member 7
chr2_+_243728434 0.01 ENSRNOT00000017252
alcohol dehydrogenase 4 (class II), pi polypeptide
chr2_+_240021152 0.01 ENSRNOT00000012473
tachykinin receptor 3
chr12_+_39913628 0.01 ENSRNOT00000046604
coiled-coil domain containing 63
chr14_-_17436897 0.01 ENSRNOT00000003277
USO1 vesicle transport factor
chr1_+_84304228 0.01 ENSRNOT00000024771
periaxin
chr2_-_21698937 0.01 ENSRNOT00000080165

chr4_+_99823252 0.01 ENSRNOT00000013587
RNA polymerase I subunit A
chr10_+_15620871 0.01 ENSRNOT00000089435
ENSRNOT00000066430
NPR3-like, GATOR1 complex subunit
chr12_+_31536951 0.01 ENSRNOT00000086078
RIMS binding protein 2
chr1_+_280423079 0.01 ENSRNOT00000011983
solute carrier family 18 member A2
chr3_-_176548208 0.01 ENSRNOT00000084339
cholinergic receptor nicotinic alpha 4 subunit
chr10_+_12980674 0.01 ENSRNOT00000004638
BICD family like cargo adaptor 2
chr3_+_35014538 0.01 ENSRNOT00000006341
kinesin family member 5C
chr2_-_218951030 0.01 ENSRNOT00000019172
solute carrier family 30 member 7
chr2_-_56679955 0.01 ENSRNOT00000016722
EGF-like, fibronectin type III and laminin G domains
chr13_-_72890841 0.01 ENSRNOT00000093726
similar to 6820428L09 protein
chr1_+_199248470 0.00 ENSRNOT00000025933
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr20_+_5442390 0.00 ENSRNOT00000037499
ribosomal protein S18
chr1_+_282568287 0.00 ENSRNOT00000015997
carboxylesterase 2I
chr15_+_344360 0.00 ENSRNOT00000077671
potassium calcium-activated channel subfamily M alpha 1
chr1_-_187779675 0.00 ENSRNOT00000024648
ADP-ribosylation factor like GTPase 6 interacting protein 1
chr10_+_56237755 0.00 ENSRNOT00000016163
FMR1 autosomal homolog 2
chr2_-_218658761 0.00 ENSRNOT00000018318
sphingosine-1-phosphate receptor 1
chr1_-_216971183 0.00 ENSRNOT00000077911
MAS related GPR family member E
chr1_-_65681440 0.00 ENSRNOT00000026305
zinc finger protein 128
chr2_+_27365148 0.00 ENSRNOT00000021549
collagen type IV alpha 3 binding protein
chr3_+_8534440 0.00 ENSRNOT00000045827
ENSRNOT00000082672
spectrin, alpha, non-erythrocytic 1
chr1_+_260093641 0.00 ENSRNOT00000019521
cyclin J
chr3_-_11317049 0.00 ENSRNOT00000030558
SWI5 homologous recombination repair protein
chr3_-_14019204 0.00 ENSRNOT00000072400
ENSRNOT00000092918
TNF receptor-associated factor 1
chr6_-_43448280 0.00 ENSRNOT00000081110
ADAM metallopeptidase domain 17
chr18_+_30398113 0.00 ENSRNOT00000027206
protocadherin beta 5
chr18_-_81807627 0.00 ENSRNOT00000020376
translocase of inner mitochondrial membrane 21
chr14_+_13192347 0.00 ENSRNOT00000000092
anthrax toxin receptor 2
chr3_-_2431148 0.00 ENSRNOT00000012978
negative elongation factor complex member B
chr10_-_35833861 0.00 ENSRNOT00000049942
calnexin
chr7_-_70476340 0.00 ENSRNOT00000006800
Rho guanine nucleotide exchange factor 25
chr8_-_55681930 0.00 ENSRNOT00000065744
colorectal cancer associated 2
chr1_+_72635267 0.00 ENSRNOT00000090636
interleukin 11
chr4_-_132111079 0.00 ENSRNOT00000013719
eukaryotic translation initiation factor 4E family member 3
chr3_+_72447969 0.00 ENSRNOT00000012022
structure specific recognition protein 1
chr1_+_245396989 0.00 ENSRNOT00000016757
potassium voltage-gated channel modifier subfamily V member 2
chr1_+_192169841 0.00 ENSRNOT00000025832
calcineurin-like EF hand protein 2
chr3_+_79860179 0.00 ENSRNOT00000081160
ENSRNOT00000068444
receptor-associated protein of the synapse
chr3_-_161212188 0.00 ENSRNOT00000065751
WAP four-disulfide core domain 3
chr3_-_93734282 0.00 ENSRNOT00000012428
cell cycle associated protein 1
chr5_-_74190991 0.00 ENSRNOT00000090366
erythrocyte membrane protein band 4.1 like 4B
chr20_+_5125349 0.00 ENSRNOT00000085598
ENSRNOT00000001129
BCL2-associated athanogene 6
chr16_-_74864816 0.00 ENSRNOT00000017164
ALG11, alpha-1,2-mannosyltransferase
chr4_-_6062641 0.00 ENSRNOT00000074846
chaperonin containing TCP1, subunit 8 (theta)-like 1
chrX_+_65226748 0.00 ENSRNOT00000076181
moesin
chr16_-_5795825 0.00 ENSRNOT00000048043
calcium voltage-gated channel auxiliary subunit alpha2delta 3
chr6_+_105364668 0.00 ENSRNOT00000009513
ENSRNOT00000087090
tetratricopeptide repeat domain 9
chr2_+_104416972 0.00 ENSRNOT00000017125
tripartite motif-containing 55

Network of associatons between targets according to the STRING database.

First level regulatory network of Zic3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002554 serotonin secretion by platelet(GO:0002554)
0.0 0.1 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:2000546 positive regulation of fat cell proliferation(GO:0070346) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.1 GO:0005607 laminin-2 complex(GO:0005607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)