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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Zic2

Z-value: 0.87

Motif logo

Transcription factors associated with Zic2

Gene Symbol Gene ID Gene Info
ENSRNOG00000054879 Zic family member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zic2rn6_v1_chr15_+_108908607_108908607-0.553.4e-01Click!

Activity profile of Zic2 motif

Sorted Z-values of Zic2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_15577977 0.67 ENSRNOT00000052292
hemoglobin alpha, adult chain 3
chr1_-_166943592 0.65 ENSRNOT00000026962
folate receptor 1
chr1_+_242572533 0.37 ENSRNOT00000035123
transmembrane protein 252
chr20_-_11620945 0.36 ENSRNOT00000079725
keratin associated protein 12-2
chr6_-_108415093 0.33 ENSRNOT00000031650
synapse differentiation inducing 1-like
chr1_-_216080287 0.32 ENSRNOT00000027682
tyrosine hydroxylase
chr8_+_111107358 0.31 ENSRNOT00000011203
anaphase promoting complex subunit 13
chrX_-_23187341 0.31 ENSRNOT00000000180
5'-aminolevulinate synthase 2
chr1_-_89369960 0.30 ENSRNOT00000028545
hepcidin antimicrobial peptide
chr2_+_127538659 0.30 ENSRNOT00000093483
ENSRNOT00000058476
solute carrier family 25 member 31
chr10_-_97582188 0.29 ENSRNOT00000005076
regulator of G-protein signaling 9
chr12_+_47698947 0.29 ENSRNOT00000001586
transient receptor potential cation channel, subfamily V, member 4
chr9_+_10956056 0.27 ENSRNOT00000073930
perilipin 5
chr2_-_202816562 0.27 ENSRNOT00000020401
family with sequence similarity 46, member C
chr1_+_91152635 0.27 ENSRNOT00000073438
dermokine-like
chr9_-_43127887 0.27 ENSRNOT00000021685
ankyrin repeat domain 39
chr2_-_187668677 0.26 ENSRNOT00000056898
ENSRNOT00000092563
TSSK6 activating co-chaperone
chr20_+_13662867 0.25 ENSRNOT00000032257
similar to Homo sapiens fetal lung specific expression unknown
chrX_-_106607352 0.25 ENSRNOT00000082858

chr17_-_15881327 0.24 ENSRNOT00000022341
ninjurin 1
chr5_+_153197459 0.24 ENSRNOT00000023187
Rh blood group, D antigen
chr10_-_90307658 0.24 ENSRNOT00000092102
solute carrier family 4 member 1
chr1_+_166893734 0.23 ENSRNOT00000026702
paired-like homeobox 2a
chr13_-_42263024 0.23 ENSRNOT00000004741
Ly6/Plaur domain containing 1
chr1_-_12952906 0.22 ENSRNOT00000078193
hypothetical protein LOC100360362
chr4_-_122237754 0.22 ENSRNOT00000029915
carbohydrate sulfotransferase 13
chr5_+_157801163 0.21 ENSRNOT00000024160
aldo-keto reductase family 7 member A3
chr7_-_70842405 0.21 ENSRNOT00000047449
neurexophilin 4
chr7_-_12646960 0.21 ENSRNOT00000014687
proteinase 3
chr3_-_160853650 0.21 ENSRNOT00000018844
matrilin 4
chr3_+_148234193 0.21 ENSRNOT00000010418
cytochrome c oxidase subunit 4i2
chr5_+_135687538 0.21 ENSRNOT00000091664

chr1_-_215858034 0.20 ENSRNOT00000027656
insulin 2
chr5_-_68139199 0.20 ENSRNOT00000009987
phospholipid phosphatase related 1
chr11_+_32211115 0.20 ENSRNOT00000087452
mitochondrial ribosomal protein S6
chr12_-_22478752 0.20 ENSRNOT00000089392
ENSRNOT00000086915
acetylcholinesterase
chr6_+_123974798 0.20 ENSRNOT00000075794
potassium two pore domain channel subfamily K member 13
chr4_-_100883038 0.20 ENSRNOT00000041880
thymosin, beta 10-like
chr4_+_57855416 0.19 ENSRNOT00000029608
carboxypeptidase A2
chr8_-_97083120 0.19 ENSRNOT00000018603
transmembrane p24 trafficking protein 3
chr15_+_34584320 0.19 ENSRNOT00000048255

chr15_-_64191115 0.19 ENSRNOT00000013868
40S ribosomal protein S17-like
chr10_-_57671080 0.18 ENSRNOT00000082511
hypothetical protein LOC691995
chr15_+_44441856 0.18 ENSRNOT00000018006
gonadotropin releasing hormone 1
chr10_+_103438303 0.18 ENSRNOT00000085262
Cd300a molecule
chr11_+_82415995 0.18 ENSRNOT00000051772

chr7_-_18577325 0.18 ENSRNOT00000084308
ENSRNOT00000090849
membrane associated ring-CH-type finger 2
chr2_-_88135410 0.18 ENSRNOT00000014180
carbonic anhydrase 3
chr18_+_62805410 0.18 ENSRNOT00000086679
G protein subunit alpha L
chr5_+_135997052 0.17 ENSRNOT00000024921
Tctex1 domain containing 4
chr7_-_12609694 0.17 ENSRNOT00000093287
ENSRNOT00000079485
KISS1 receptor
chr6_-_123577695 0.17 ENSRNOT00000006604
forkhead box N3
chr6_-_45669148 0.17 ENSRNOT00000010092
radical S-adenosyl methionine domain containing 2
chr19_-_53754602 0.17 ENSRNOT00000035651
family with sequence similarity 92, member B
chr2_-_251970768 0.17 ENSRNOT00000020141
WD repeat domain 63
chr6_+_127333590 0.17 ENSRNOT00000063970
interferon, alpha-inducible protein 27
chr2_+_225645568 0.16 ENSRNOT00000017878
ATP binding cassette subfamily A member 4
chr10_-_91047177 0.16 ENSRNOT00000003986
complement C1q like 1
chr17_+_8299131 0.16 ENSRNOT00000083687
predicted gene 45623
chr3_+_161236898 0.16 ENSRNOT00000082303
ENSRNOT00000020323
ubiquitin-conjugating enzyme E2C
chr17_+_47301511 0.16 ENSRNOT00000092051
ENSRNOT00000087178
NME/NM23 family member 8
chr19_-_41541986 0.15 ENSRNOT00000059172
transducin-like enhancer protein 2-like
chr5_-_38923095 0.15 ENSRNOT00000009146

chr10_-_45534570 0.15 ENSRNOT00000058362
gap junction protein, gamma 2
chr16_+_83161880 0.15 ENSRNOT00000080793
RIKEN cDNA 1700016D06 gene
chr10_-_48038647 0.15 ENSRNOT00000078448
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr13_+_52588917 0.15 ENSRNOT00000011999
pleckstrin homology-like domain, family A, member 3
chr8_+_71822129 0.15 ENSRNOT00000089147
death-associated protein kinase 2
chr10_-_87261717 0.15 ENSRNOT00000015740
keratin 27
chr8_-_75995371 0.15 ENSRNOT00000014014
forkhead box B1
chr9_+_98490608 0.15 ENSRNOT00000027232
kelch-like family member 30
chr10_+_4313100 0.15 ENSRNOT00000074487
eukaryotic peptide chain release factor GTP-binding subunit ERF3B-like
chr6_+_86921721 0.15 ENSRNOT00000048726
ubiquitin-like protein fubi and ribosomal protein S30-like
chr14_-_10694164 0.15 ENSRNOT00000080099

chr15_-_61873406 0.14 ENSRNOT00000045115
LRRGT00053-like
chr7_+_92234597 0.14 ENSRNOT00000067491
ENSRNOT00000089991
mediator complex subunit 30
chr19_+_33160180 0.14 ENSRNOT00000016422
POU class 4 homeobox 2
chr13_+_95416242 0.14 ENSRNOT00000072611
ribosomal protein L30-like 1
chr20_+_8486265 0.14 ENSRNOT00000072213
40S ribosomal protein S20-like
chr10_+_14257001 0.14 ENSRNOT00000021075
mitochondrial ribosomal protein S34
chr10_-_109891879 0.14 ENSRNOT00000077930
centromere protein X
chr16_-_47207487 0.14 ENSRNOT00000059459
dCMP deaminase
chr8_+_28045288 0.14 ENSRNOT00000085997
thymocyte nuclear protein 1
chr10_+_108395860 0.13 ENSRNOT00000075796
glucosidase, alpha, acid
chr2_-_196046311 0.13 ENSRNOT00000028484
proteasome subunit beta 4
chr10_+_49538588 0.13 ENSRNOT00000081415
peripheral myelin protein 22
chr17_-_9695292 0.13 ENSRNOT00000036162
proline rich 7 (synaptic)
chr6_+_104475036 0.13 ENSRNOT00000070995
sushi domain containing 6
chr4_+_25435873 0.13 ENSRNOT00000000018
STEAP family member 1
chr20_+_18547370 0.13 ENSRNOT00000000750
ubiquitin-conjugating enzyme E2D 1
chr20_-_5107899 0.13 ENSRNOT00000038130
ENSRNOT00000086413
lymphocyte antigen 6 complex, locus G5B
chr3_+_147226004 0.13 ENSRNOT00000012765
transmembrane protein 74B
chr1_-_81193729 0.13 ENSRNOT00000026268
tescalcin-like
chr9_-_93607087 0.13 ENSRNOT00000025262
phosphodiesterase 6D
chr3_-_147851768 0.13 ENSRNOT00000032881
neurensin 2
chr1_-_48360131 0.13 ENSRNOT00000051927
ENSRNOT00000023116
solute carrier family 22 member 2
chr9_-_97151832 0.13 ENSRNOT00000040169
ankyrin repeat and SOCS box-containing 18
chr18_+_70739492 0.13 ENSRNOT00000085601
acetyl-CoA acyltransferase 2
chr19_+_55246926 0.13 ENSRNOT00000017358
interleukin 17C
chr5_+_147288723 0.13 ENSRNOT00000033285
transmembrane protein 54
chr9_+_68414339 0.13 ENSRNOT00000040778
par-3 family cell polarity regulator beta
chr17_-_9791781 0.13 ENSRNOT00000090536
regulator of G-protein signaling 14
chr10_+_86950557 0.13 ENSRNOT00000014153
insulin-like growth factor binding protein 4
chr7_-_119623072 0.13 ENSRNOT00000050511
thiosulfate sulfurtransferase
chr9_+_82556573 0.13 ENSRNOT00000026860
desmin
chr16_+_20352480 0.12 ENSRNOT00000025956
arrestin domain containing 2
chr1_+_215609036 0.12 ENSRNOT00000076187
troponin I2, fast skeletal type
chr4_+_44321883 0.12 ENSRNOT00000091095
testin LIM domain protein
chr5_-_76129441 0.12 ENSRNOT00000020335
prostaglandin reductase 1
chr1_-_212549477 0.12 ENSRNOT00000024765
calcyon neuron-specific vesicular protein
chr15_+_45422010 0.12 ENSRNOT00000012231
ribonuclease H2, subunit B
chr9_+_95285592 0.12 ENSRNOT00000063853
UDP glucuronosyltransferase family 1 member A5
chr1_-_57518458 0.12 ENSRNOT00000002040
programmed cell death 2
chr15_+_24159647 0.12 ENSRNOT00000082675
galectin 3
chr9_+_69790831 0.12 ENSRNOT00000045156
ribosomal protein L37-like
chr6_+_108488678 0.12 ENSRNOT00000016089
iron-sulfur cluster assembly 2
chr11_+_75434197 0.12 ENSRNOT00000032569
Mab-21 domain containing 2
chr1_-_222250980 0.12 ENSRNOT00000028734
nudix hydrolase 22
chr5_-_158313426 0.12 ENSRNOT00000025488
paired box 7
chr1_-_82166363 0.12 ENSRNOT00000027774
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3
chr1_+_141986145 0.12 ENSRNOT00000030914
semaphorin 4B
chr1_-_146823762 0.12 ENSRNOT00000018098
zinc finger AN1-type containing 6
chr8_-_79660439 0.11 ENSRNOT00000089949
cell cycle progression 1, opposite strand
chr5_+_131257127 0.11 ENSRNOT00000010628
BEN domain containing 5
chr4_+_67378188 0.11 ENSRNOT00000030892
NADH:ubiquinone oxidoreductase subunit B2
chr10_+_89635675 0.11 ENSRNOT00000028179
similar to SAP18
chrX_-_72078551 0.11 ENSRNOT00000076978
ribosomal protein S4, X-linked
chr1_+_31967978 0.11 ENSRNOT00000081471
ENSRNOT00000021532
thyroid hormone receptor interactor 13
chr9_+_98505259 0.11 ENSRNOT00000051810
erythroferrone
chr7_-_130827152 0.11 ENSRNOT00000019406
synaptotagmin 10
chr7_+_120153184 0.11 ENSRNOT00000013538
galectin 1
chr4_+_56744561 0.11 ENSRNOT00000009737
ATPase H+ transporting V1 subunit F
chr3_-_72219246 0.11 ENSRNOT00000009903
smoothelin-like 1
chr11_+_60907015 0.11 ENSRNOT00000002797
GTP-binding protein 8 (putative)
chr5_-_159336429 0.11 ENSRNOT00000009230
peptidyl arginine deiminase 3
chr8_+_28045093 0.11 ENSRNOT00000073373
thymocyte nuclear protein 1
chrX_+_70461718 0.11 ENSRNOT00000078233
ENSRNOT00000003789
kinesin family member 4A
chr5_+_34040258 0.11 ENSRNOT00000009758
gamma-glutamyl hydrolase
chr7_-_123193761 0.11 ENSRNOT00000007164
phosphomannomutase 1
chr13_+_42220251 0.11 ENSRNOT00000078185

chr7_-_12399910 0.11 ENSRNOT00000021677
RGD1562114
chr3_-_113376751 0.11 ENSRNOT00000030019
cation channel, sperm associated 2
chr6_+_128048099 0.11 ENSRNOT00000084685
ENSRNOT00000087017
Ab1-233
chr17_-_9792007 0.11 ENSRNOT00000021596
regulator of G-protein signaling 14
chr5_-_107857320 0.10 ENSRNOT00000008898
cyclin-dependent kinase inhibitor 2B
chr4_+_7076759 0.10 ENSRNOT00000066598
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_-_254671778 0.10 ENSRNOT00000025493
5-hydroxytryptamine receptor 7
chr8_+_39305128 0.10 ENSRNOT00000008285
fasciculation and elongation protein zeta 1
chr10_-_56935141 0.10 ENSRNOT00000025910
arachidonate 12-lipoxygenase, epidermal
chr8_+_132241134 0.10 ENSRNOT00000006055
C-type lectin domain family 3, member B
chr19_-_57699113 0.10 ENSRNOT00000026767
egl-9 family hypoxia-inducible factor 1
chr7_-_132757558 0.10 ENSRNOT00000021153
solute carrier family 2 member 13
chr7_+_142941122 0.10 ENSRNOT00000055353

chr19_+_10731855 0.10 ENSRNOT00000022277
plasmolipin
chr10_+_3218466 0.10 ENSRNOT00000093629
ENSRNOT00000093338
ENSRNOT00000077695
N-terminal asparagine amidase
chr17_+_10537365 0.10 ENSRNOT00000023651
clathrin, light chain B
chr1_-_254671596 0.10 ENSRNOT00000025450
5-hydroxytryptamine receptor 7
chrX_+_15273933 0.10 ENSRNOT00000075082
erythroid transcription factor
chr4_-_165026414 0.10 ENSRNOT00000071421
killer cell lectin-like receptor, subfamily A, member 1
chr17_-_29438668 0.10 ENSRNOT00000021660
phenylalanyl-tRNA synthetase 2, mitochondrial
chr2_+_263895241 0.10 ENSRNOT00000014126
ENSRNOT00000014034
prostaglandin E receptor 3
chr20_-_56197025 0.09 ENSRNOT00000073028
CD99 molecule
chr3_-_176465162 0.09 ENSRNOT00000048807
Sodium/potassium transporting ATPase interacting 4
chr19_-_43841795 0.09 ENSRNOT00000079539
lactate dehydrogenase D
chr9_+_44003322 0.09 ENSRNOT00000051584

chr10_-_15098791 0.09 ENSRNOT00000026139
chromosome transmission fidelity factor 18
chr2_+_240461505 0.09 ENSRNOT00000019507
3-hydroxybutyrate dehydrogenase 2
chr5_+_2042991 0.09 ENSRNOT00000050236
elongin C
chr1_-_77830399 0.09 ENSRNOT00000052231
ribosomal protein L9-like
chrX_+_92596378 0.09 ENSRNOT00000045001
protocadherin 11 X-linked
chr10_+_15495684 0.09 ENSRNOT00000027662
mitochondrial ribosomal protein L28
chr17_+_47662532 0.09 ENSRNOT00000081314
STARD3 N-terminal like
chr5_+_154037202 0.09 ENSRNOT00000049459
interferon, lambda receptor 1
chr2_+_188561429 0.09 ENSRNOT00000076458
ENSRNOT00000027867
keratinocyte associated protein 2
chr19_-_9843673 0.09 ENSRNOT00000015795
GINS complex subunit 3
chr13_+_82438697 0.09 ENSRNOT00000003759
selectin P
chr3_+_159368273 0.09 ENSRNOT00000041688
serum/glucocorticoid regulated kinase 2
chr5_+_171242897 0.09 ENSRNOT00000032859
similar to RIKEN cDNA A430005L14
chr7_-_119158173 0.09 ENSRNOT00000067483
ENSRNOT00000078528
thioredoxin 2
chr15_-_95514259 0.09 ENSRNOT00000038433
SLIT and NTRK-like family, member 6
chr10_+_4953879 0.09 ENSRNOT00000003455
transition protein 2
chr10_-_57436368 0.09 ENSRNOT00000056608
SLP adaptor and CSK interacting membrane protein
chr10_-_62648844 0.09 ENSRNOT00000034282
abhydrolase domain containing 15
chr12_-_12025549 0.09 ENSRNOT00000001331
neuronal pentraxin 2
chr7_-_107775712 0.09 ENSRNOT00000010811
ENSRNOT00000093459
N-myc downstream regulated 1
chr14_-_41786084 0.09 ENSRNOT00000059439
glutaredoxin and cysteine rich domain containing 1
chr18_-_15637715 0.08 ENSRNOT00000022270
desmoglein 2
chr5_+_114516889 0.08 ENSRNOT00000011767
FGGY carbohydrate kinase domain containing
chr9_+_65172194 0.08 ENSRNOT00000040493

chr1_-_264303762 0.08 ENSRNOT00000019039
NADH:ubiquinone oxidoreductase subunit B8
chr14_+_10581136 0.08 ENSRNOT00000002987
coenzyme Q2, polyprenyltransferase
chr16_-_61753476 0.08 ENSRNOT00000016792
store-operated calcium entry-associated regulatory factor
chr10_+_59743544 0.08 ENSRNOT00000093497
ENSRNOT00000056460
Tax1 binding protein 3
chr17_+_29438980 0.08 ENSRNOT00000072056
LYR motif containing 4
chr10_+_43871613 0.08 ENSRNOT00000080540
ENSRNOT00000003797
RoBo-1
chr16_+_70834957 0.08 ENSRNOT00000019594
farnesyltransferase, CAAX box, alpha
chr10_-_72556564 0.08 ENSRNOT00000048373

chr6_+_26797126 0.08 ENSRNOT00000010586
cell growth regulator with EF hand domain 1
chr1_+_79030291 0.08 ENSRNOT00000037086
ENSRNOT00000088925
carcinoembryonic antigen gene family 4
chr3_-_143223615 0.08 ENSRNOT00000007175
cystatin C

Network of associatons between targets according to the STRING database.

First level regulatory network of Zic2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.1 0.3 GO:0072566 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.3 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.2 GO:0021558 trochlear nerve development(GO:0021558)
0.1 0.3 GO:1901423 response to benzene(GO:1901423)
0.1 0.2 GO:0010070 zygote asymmetric cell division(GO:0010070)
0.1 0.3 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760) cellular response to bile acid(GO:1903413)
0.1 0.2 GO:0046223 toxin catabolic process(GO:0009407) mycotoxin metabolic process(GO:0043385) mycotoxin catabolic process(GO:0043387) aflatoxin metabolic process(GO:0046222) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound metabolic process(GO:1901376) organic heteropentacyclic compound catabolic process(GO:1901377)
0.1 0.2 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1 0.7 GO:0015671 oxygen transport(GO:0015671)
0.1 0.2 GO:0060101 negative regulation of phagocytosis, engulfment(GO:0060101) negative regulation of eosinophil migration(GO:2000417)
0.1 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.2 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.1 0.2 GO:1905133 metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.0 0.1 GO:2000978 negative regulation of forebrain neuron differentiation(GO:2000978)
0.0 0.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.2 GO:0010037 response to carbon dioxide(GO:0010037)
0.0 0.0 GO:1904170 regulation of bleb assembly(GO:1904170)
0.0 0.2 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.1 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769)
0.0 0.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.1 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.2 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0046865 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0 0.1 GO:0030221 basophil differentiation(GO:0030221)
0.0 0.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.4 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.2 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0010710 regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.1 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.0 0.1 GO:1990401 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling(GO:0060683) embryonic lung development(GO:1990401)
0.0 0.1 GO:1904178 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
0.0 0.1 GO:0008358 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.0 0.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.2 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.0 0.1 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0071799 bud outgrowth involved in lung branching(GO:0060447) response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.0 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0 0.0 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.0 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0097327 response to antineoplastic agent(GO:0097327)
0.0 0.1 GO:1904045 cellular response to aldosterone(GO:1904045)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.0 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0003164 His-Purkinje system development(GO:0003164)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.0 0.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.0 0.0 GO:0046967 cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.0 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.0 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.4 GO:0045179 apical cortex(GO:0045179)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.2 GO:1990005 granular vesicle(GO:1990005)
0.0 0.2 GO:0044301 climbing fiber(GO:0044301)
0.0 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0097598 outer dynein arm(GO:0036157) sperm cytoplasmic droplet(GO:0097598)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.0 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.0 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0099567 N-terminal myristoylation domain binding(GO:0031997) calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099567)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.0 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.0 GO:0031826 follicle-stimulating hormone receptor binding(GO:0031762) type 2A serotonin receptor binding(GO:0031826)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.0 GO:0033265 choline binding(GO:0033265)
0.0 0.0 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0032564 dATP binding(GO:0032564)
0.0 0.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)