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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Zfp524

Z-value: 0.70

Motif logo

Transcription factors associated with Zfp524

Gene Symbol Gene ID Gene Info
ENSRNOG00000016565 zinc finger protein 524

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp524rn6_v1_chr1_-_72377434_72377434-0.583.0e-01Click!

Activity profile of Zfp524 motif

Sorted Z-values of Zfp524 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_89008008 0.50 ENSRNOT00000074586
CCAAT/enhancer binding protein delta
chr10_-_97582188 0.46 ENSRNOT00000005076
regulator of G-protein signaling 9
chr16_+_20352480 0.38 ENSRNOT00000025956
arrestin domain containing 2
chr16_-_8685529 0.34 ENSRNOT00000092751
solute carrier family 18 member A3
chr18_+_63130542 0.28 ENSRNOT00000024947
tubulin, beta 6 class V
chr13_-_50499060 0.27 ENSRNOT00000065347
ENSRNOT00000076924
ethanolamine kinase 2
chr4_-_28702559 0.26 ENSRNOT00000013910
ENSRNOT00000013937
calcitonin receptor
chr2_-_257484587 0.25 ENSRNOT00000083344
nexilin (F actin binding protein)
chr9_-_5330815 0.25 ENSRNOT00000014548
solute carrier family 5 member 7
chr1_+_205842489 0.24 ENSRNOT00000081610
fibronectin type 3 and ankyrin repeat domains 1
chr11_+_67465236 0.24 ENSRNOT00000042374
stefin A2
chr7_+_141370491 0.24 ENSRNOT00000087662
glycerol-3-phosphate dehydrogenase 1
chr19_-_37427989 0.24 ENSRNOT00000022863
tubulin polymerization-promoting protein family member 3
chr19_-_11308740 0.23 ENSRNOT00000067391
metallothionein 2A
chr5_-_127983515 0.22 ENSRNOT00000043054
family with sequence similarity 159, member A
chr12_+_47698947 0.22 ENSRNOT00000001586
transient receptor potential cation channel, subfamily V, member 4
chr13_+_52588917 0.22 ENSRNOT00000011999
pleckstrin homology-like domain, family A, member 3
chr1_+_279798187 0.22 ENSRNOT00000024065
pancreatic lipase
chr12_-_22477052 0.21 ENSRNOT00000075504
acetylcholinesterase
chr9_-_82146874 0.20 ENSRNOT00000024190
FEV, ETS transcription factor
chr17_+_24416651 0.19 ENSRNOT00000024458
CD83 molecule
chr1_-_88881460 0.19 ENSRNOT00000028287
hematopoietic cell signal transducer
chr13_-_44345735 0.19 ENSRNOT00000005006
transmembrane protein 163
chr3_-_111422203 0.18 ENSRNOT00000084290
Opa interacting protein 5
chr1_+_163445527 0.18 ENSRNOT00000020520
leucine rich repeat containing 32
chr13_+_89386023 0.18 ENSRNOT00000086223
Fc fragment of IgG receptor IIIa
chr1_+_198690794 0.18 ENSRNOT00000023999
zinc finger protein 771
chr11_+_64882288 0.18 ENSRNOT00000077727
phospholipase A1 member A
chr13_+_89385859 0.18 ENSRNOT00000047434
Fc fragment of IgG receptor IIIa
chr19_+_44164935 0.18 ENSRNOT00000048998
GABA type A receptor associated protein like 2
chr4_-_10269748 0.17 ENSRNOT00000074662
family with sequence similarity 185, member A
chr20_+_32450733 0.17 ENSRNOT00000036449
radial spoke head 4 homolog A
chr11_+_47243342 0.16 ENSRNOT00000041116
NFKB inhibitor zeta
chr10_+_86303727 0.16 ENSRNOT00000037752
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr1_+_238222521 0.16 ENSRNOT00000024000
aldehyde dehydrogenase 1 family, member A1
chr11_+_32211115 0.16 ENSRNOT00000087452
mitochondrial ribosomal protein S6
chr11_+_87204175 0.16 ENSRNOT00000000306
solute carrier family 25 member 1
chr2_-_200513564 0.16 ENSRNOT00000056173
phosphoglycerate dehydrogenase
chr5_-_143062226 0.15 ENSRNOT00000029388
dynein, axonemal, light intermediate chain 1
chr10_-_54512169 0.15 ENSRNOT00000005066
cilia and flagella associated protein 52
chr19_+_25123724 0.15 ENSRNOT00000007407
hypothetical protein LOC686013
chr7_+_123573930 0.14 ENSRNOT00000066149
family with sequence similarity 109, member B
chr20_+_33945829 0.14 ENSRNOT00000064063
radial spoke head protein 4 homolog A
chr10_+_3218466 0.14 ENSRNOT00000093629
ENSRNOT00000093338
ENSRNOT00000077695
N-terminal asparagine amidase
chr1_-_212548730 0.14 ENSRNOT00000089729
calcyon neuron-specific vesicular protein
chr17_+_9736577 0.14 ENSRNOT00000066586
coagulation factor XII
chr15_+_24141651 0.14 ENSRNOT00000082304
galectin 3
chr2_+_127538659 0.14 ENSRNOT00000093483
ENSRNOT00000058476
solute carrier family 25 member 31
chr2_-_188413219 0.14 ENSRNOT00000065065
farnesyl diphosphate synthase
chr4_+_145580799 0.13 ENSRNOT00000013727
von Hippel-Lindau tumor suppressor
chr8_+_118378059 0.13 ENSRNOT00000043247

chr8_-_82351108 0.13 ENSRNOT00000013053
mitogen-activated protein kinase 6
chr11_-_36479868 0.13 ENSRNOT00000075762
non-histone chromosomal protein HMG-14-like
chr6_-_45669148 0.13 ENSRNOT00000010092
radical S-adenosyl methionine domain containing 2
chr6_+_2969333 0.13 ENSRNOT00000047356
MORN repeat containing 2
chr6_-_91518996 0.13 ENSRNOT00000005835
DNA polymerase epsilon 2, accessory subunit
chr7_+_117394372 0.13 ENSRNOT00000048706
glycosylphosphatidylinositol anchor attachment 1
chr3_+_72385666 0.13 ENSRNOT00000011168
proteoglycan 2
chr16_-_61791091 0.13 ENSRNOT00000042003
membrane bound O-acyltransferase domain containing 4
chr5_-_58106706 0.13 ENSRNOT00000019561
dynactin subunit 3
chr4_+_62780596 0.13 ENSRNOT00000073846
hypothetical protein LOC689574
chr5_-_75676584 0.12 ENSRNOT00000044348
lysophosphatidic acid receptor 1
chr17_+_15845931 0.12 ENSRNOT00000092083
caspase recruitment domain family, member 19
chr1_-_43884267 0.12 ENSRNOT00000024418
Cnksr family member 3
chr3_+_72226613 0.12 ENSRNOT00000010619
translocase of inner mitochondrial membrane 10
chr10_+_85646633 0.12 ENSRNOT00000086608
proteasome subunit beta 3
chr11_-_32088002 0.12 ENSRNOT00000002732
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr10_+_15241590 0.12 ENSRNOT00000037372
ENSRNOT00000037381
methyltransferase like 26
chr13_+_83681322 0.12 ENSRNOT00000004206
mitochondrial pyruvate carrier 2
chr9_+_100076958 0.12 ENSRNOT00000084297
dual specificity phosphatase 28
chr20_-_3819200 0.12 ENSRNOT00000000542
ENSRNOT00000081486
hydroxysteroid (17-beta) dehydrogenase 8
chr15_+_33121273 0.12 ENSRNOT00000016020
RRAD and GEM like GTPase 2
chr10_-_58924137 0.11 ENSRNOT00000066740
tektin 1
chr1_+_31967978 0.11 ENSRNOT00000081471
ENSRNOT00000021532
thyroid hormone receptor interactor 13
chr1_-_190914610 0.11 ENSRNOT00000023189
cerebellar degeneration-related protein 2
chr3_-_171342646 0.11 ENSRNOT00000071853
prostate transmembrane protein, androgen induced 1
chr17_+_70684340 0.11 ENSRNOT00000051067
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr16_+_80826681 0.11 ENSRNOT00000000123
coordinator of PRMT5 and differentiation stimulator
chr1_-_89474252 0.11 ENSRNOT00000028597
FXYD domain-containing ion transport regulator 5
chr3_-_7632345 0.11 ENSRNOT00000049889
cilia and flagella associated protein 77
chr7_-_143353925 0.11 ENSRNOT00000068533
keratin 71
chr2_-_189573280 0.11 ENSRNOT00000022897
ribosomal protein S27
chr19_+_37226186 0.11 ENSRNOT00000075933
ENSRNOT00000065013
heat shock transcription factor 4
chr13_+_88557860 0.11 ENSRNOT00000058547
SH2 domain containing 1B2
chr5_-_167999853 0.11 ENSRNOT00000087402
Parkinsonism associated deglycase
chr1_+_202432366 0.11 ENSRNOT00000027681
phospholipid phosphatase 4
chr16_+_10250404 0.11 ENSRNOT00000087037
ENSRNOT00000081183
growth differentiation factor 10
chr3_+_23301455 0.11 ENSRNOT00000019405
actin related protein 2/3 complex, subunit 5-like
chr19_+_24800072 0.11 ENSRNOT00000005470
prostaglandin E receptor 1
chr4_+_112773938 0.10 ENSRNOT00000009321
eva-1 homolog A, regulator of programmed cell death
chr11_+_30363280 0.10 ENSRNOT00000002885
superoxide dismutase 1, soluble
chr1_-_173764246 0.10 ENSRNOT00000019690
ENSRNOT00000086944
LIM domain only 1
chr17_+_18031228 0.10 ENSRNOT00000081708
thiopurine S-methyltransferase
chr6_-_27024129 0.10 ENSRNOT00000012273
dihydropyrimidinase-like 5
chr1_+_87248489 0.10 ENSRNOT00000028091
double PHD fingers 1
chr15_-_19575914 0.10 ENSRNOT00000043897

chr13_+_51972974 0.10 ENSRNOT00000008164
ADP-ribosylation factor like GTPase 8A
chr9_-_17698569 0.10 ENSRNOT00000087528
mitochondrial ribosomal protein L14
chr10_+_86340940 0.10 ENSRNOT00000073486
phenylethanolamine-N-methyltransferase
chr20_-_5192000 0.10 ENSRNOT00000079677
tumor necrosis factor
chr16_-_74408030 0.10 ENSRNOT00000026418
solute carrier family 20 member 2
chr19_+_24456976 0.10 ENSRNOT00000004900
uncoupling protein 1
chr17_-_2705123 0.09 ENSRNOT00000024940
olfactory receptor 1652
chr2_-_211017778 0.09 ENSRNOT00000026883
synaptophysin-like 2
chr9_+_17784468 0.09 ENSRNOT00000026831
solute carrier family 29 member 1
chr19_+_21372163 0.09 ENSRNOT00000020329
siah E3 ubiquitin protein ligase 1
chrX_-_20807216 0.09 ENSRNOT00000075757
family with sequence similarity 156, member B
chr20_-_1984737 0.09 ENSRNOT00000040232
ENSRNOT00000051634
ENSRNOT00000079445
gamma-aminobutyric acid type B receptor subunit 1
chr17_+_16333415 0.09 ENSRNOT00000060550
protein tyrosine phosphatase domain containing 1
chr11_-_61530567 0.09 ENSRNOT00000076277
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr5_-_145392123 0.09 ENSRNOT00000019266
gap junction protein, beta 3
chr19_+_16417817 0.09 ENSRNOT00000015272
iroquois homeobox 5
chr6_+_111296417 0.09 ENSRNOT00000075425
activator of Hsp90 ATPase activity 1
chr2_+_204932159 0.09 ENSRNOT00000078376
nerve growth factor
chr10_+_14598014 0.09 ENSRNOT00000068336
TSR3, 20S rRNA accumulation
chr19_-_19376789 0.09 ENSRNOT00000065103
nucleotide-binding oligomerization domain containing 2
chr20_+_4855829 0.09 ENSRNOT00000001110
tumor necrosis factor-like
chr17_-_53102342 0.09 ENSRNOT00000073834
proteasome subunit alpha 2
chr4_+_78735279 0.09 ENSRNOT00000011970
mitochondrial assembly of ribosomal large subunit 1
chr17_-_62299655 0.09 ENSRNOT00000024855
gap junction protein, delta 4
chr5_+_14890408 0.09 ENSRNOT00000033116
SRY box 17
chr10_+_64556064 0.09 ENSRNOT00000010778
translocase of inner mitochondrial membrane 22
chr6_+_75429729 0.09 ENSRNOT00000043250
ribosomal protein S10-like 1
chr7_-_67345295 0.09 ENSRNOT00000087045
ENSRNOT00000005829
arginine vasopressin receptor 1A
chr3_+_160908769 0.09 ENSRNOT00000030054
Sys1 golgi trafficking protein
chr13_+_82298534 0.09 ENSRNOT00000003636
methyltransferase like 18
chr4_+_171748273 0.09 ENSRNOT00000009998
deoxyribose-phosphate aldolase
chr13_+_49074644 0.09 ENSRNOT00000000041
kelch domain containing 8A
chr20_-_10842370 0.09 ENSRNOT00000001580
heat shock transcription factor 2 binding protein
chr12_-_18540166 0.09 ENSRNOT00000001792
interleukin 3 receptor subunit alpha
chr1_-_101514547 0.09 ENSRNOT00000079633
protein phosphatase 1, regulatory subunit 15A
chr2_-_39434560 0.09 ENSRNOT00000090193
NADH:ubiquinone oxidoreductase complex assembly factor 2
chr3_+_8450612 0.09 ENSRNOT00000040457
outer dense fiber of sperm tails 2
chr9_-_99818262 0.09 ENSRNOT00000056600
COP9 signalosome subunit 9
chr8_+_21663325 0.09 ENSRNOT00000027749
ubiquitin-like 5
chr1_+_16910069 0.08 ENSRNOT00000020015
aldehyde dehydrogenase 8 family, member A1
chr3_-_81282157 0.08 ENSRNOT00000051258
LARGE xylosyl- and glucuronyltransferase 2
chr2_-_143104412 0.08 ENSRNOT00000058116
ubiquitin-fold modifier 1
chr1_-_52894832 0.08 ENSRNOT00000016471
T brachyury transcription factor
chr8_+_119135013 0.08 ENSRNOT00000056114
protease, serine, 50
chr9_+_43259709 0.08 ENSRNOT00000022487
cytochrome c oxidase subunit 5B
chr12_+_37211316 0.08 ENSRNOT00000032739
coiled-coil domain containing 92
chr6_+_8346704 0.08 ENSRNOT00000092218

chr20_+_3744395 0.08 ENSRNOT00000086065
transcription factor 19
chr11_+_64790801 0.08 ENSRNOT00000004023
translocase of inner mitochondrial membrane domain containing 1
chr16_-_8686131 0.08 ENSRNOT00000080202
choline O-acetyltransferase
chr5_+_172648950 0.08 ENSRNOT00000055361
Fanconi anemia core complex associated protein 20
chrX_+_26294066 0.08 ENSRNOT00000037862
holocytochrome c synthase
chr7_+_2458833 0.08 ENSRNOT00000085092
nascent polypeptide-associated complex alpha subunit
chr2_+_193572053 0.08 ENSRNOT00000056479

chr3_-_161027943 0.08 ENSRNOT00000078633
serine peptidase inhibitor, Kunitz type, 3
chr1_-_201110928 0.08 ENSRNOT00000027721
NSE4 homolog A, SMC5-SMC6 complex component
chr15_+_48327461 0.08 ENSRNOT00000018071
integrator complex subunit 9
chrX_-_111942749 0.08 ENSRNOT00000087583

chr1_-_216750844 0.08 ENSRNOT00000054862
nucleosome assembly protein 1-like 4
chr8_+_50604768 0.08 ENSRNOT00000059383

chr4_-_157252565 0.08 ENSRNOT00000079947
protein tyrosine phosphatase, non-receptor type 6
chr7_+_3320103 0.08 ENSRNOT00000090381
Cd63 molecule
chr3_+_140106766 0.08 ENSRNOT00000014046
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr1_-_263920934 0.08 ENSRNOT00000090755
ENSRNOT00000017006
biogenesis of lysosomal organelles complex-1, subunit 2
chr1_+_65537640 0.08 ENSRNOT00000031007
ubiquitin-conjugating enzyme E2M
chr1_+_78833157 0.08 ENSRNOT00000022461
prostaglandin I2 (prostacyclin) receptor (IP)
chr7_+_11301957 0.08 ENSRNOT00000027847
tight junction protein 3
chr1_+_198259496 0.08 ENSRNOT00000026955
family with sequence similarity 57, member B
chr10_-_13542077 0.08 ENSRNOT00000008736
ATPase H+ transporting V0 subunit C
chr5_-_152464850 0.08 ENSRNOT00000021937
zinc finger protein 593
chr4_-_147719072 0.08 ENSRNOT00000014493
ribosomal protein L32
chr16_+_54332660 0.08 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr3_+_168124673 0.08 ENSRNOT00000070809
prefoldin subunit 4
chr7_+_11784341 0.08 ENSRNOT00000026155
pleckstrin homology domain containing J1
chr12_-_16126953 0.07 ENSRNOT00000001682
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_-_119714302 0.07 ENSRNOT00000013299
RAB43, member RAS oncogene family
chr3_-_168018410 0.07 ENSRNOT00000087579
breast carcinoma amplified sequence 1
chr1_+_225037737 0.07 ENSRNOT00000077959
BSCL2, seipin lipid droplet biogenesis associated
chr2_+_188784222 0.07 ENSRNOT00000028095
phosphomevalonate kinase
chrX_-_14220662 0.07 ENSRNOT00000045753
sushi-repeat-containing protein, X-linked
chr7_+_125576327 0.07 ENSRNOT00000016679
proline rich 5
chr6_+_108488678 0.07 ENSRNOT00000016089
iron-sulfur cluster assembly 2
chr13_-_36022197 0.07 ENSRNOT00000091280
cilia and flagella associated protein 221
chr20_+_13827132 0.07 ENSRNOT00000001664
D-dopachrome tautomerase
chr9_-_82673898 0.07 ENSRNOT00000027165
chondroitin polymerizing factor
chr1_-_77830399 0.07 ENSRNOT00000052231
ribosomal protein L9-like
chr10_+_11046221 0.07 ENSRNOT00000005109
NmrA like redox sensor 1
chr20_+_3990820 0.07 ENSRNOT00000000528
proteasome subunit beta 8
chr8_-_91338843 0.07 ENSRNOT00000012999
ELOVL fatty acid elongase 4
chr7_+_2458264 0.07 ENSRNOT00000003550
nascent polypeptide-associated complex alpha subunit
chr1_+_191829555 0.07 ENSRNOT00000067138
sodium channel epithelial 1 beta subunit
chr1_+_216254979 0.07 ENSRNOT00000046669
tumor suppressing subtransferable candidate 4
chrX_-_13116743 0.07 ENSRNOT00000004305
MID1 interacting protein 1
chr10_+_43601689 0.07 ENSRNOT00000029238
mitochondrial ribosomal protein L22
chr14_-_37475418 0.07 ENSRNOT00000002996
OCIA domain containing 1
chr6_-_108488330 0.07 ENSRNOT00000016076
NPC intracellular cholesterol transporter 2
chr7_+_34326087 0.07 ENSRNOT00000006971
histidine ammonia lyase
chr1_-_1474846 0.07 ENSRNOT00000028992
retinoic acid early transcript delta
chr7_-_18585313 0.07 ENSRNOT00000010399
membrane associated ring-CH-type finger 2
chr5_+_131719922 0.07 ENSRNOT00000010524
spermatogenesis associated 6
chr9_+_102862890 0.07 ENSRNOT00000050494
ENSRNOT00000080129
family with sequence similarity 174, member A
chr5_-_139505065 0.07 ENSRNOT00000013899
CTP synthase 1
chr1_+_167538744 0.07 ENSRNOT00000093070
ribonucleotide reductase catalytic subunit M1
chr17_+_76079720 0.07 ENSRNOT00000073933
proline and serine rich 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp524

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.2 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.1 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.3 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.2 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
0.0 0.3 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.1 GO:0090648 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703) response to environmental enrichment(GO:0090648) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.1 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0002876 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.0 0.2 GO:0015746 citrate transport(GO:0015746)
0.0 0.2 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:1903195 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) TRAIL receptor biosynthetic process(GO:0045557) regulation of TRAIL receptor biosynthetic process(GO:0045560) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.2 GO:0097332 response to antipsychotic drug(GO:0097332)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0035419 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419)
0.0 0.1 GO:0061010 inner cell mass cellular morphogenesis(GO:0001828) endodermal cell fate determination(GO:0007493) gall bladder development(GO:0061010)
0.0 0.3 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.4 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 0.1 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0071673 positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.0 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.1 GO:0014028 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) notochord formation(GO:0014028) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0000053 argininosuccinate metabolic process(GO:0000053)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.0 GO:1904313 response to methamphetamine hydrochloride(GO:1904313)
0.0 0.1 GO:0033123 positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0 0.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.0 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0050904 diapedesis(GO:0050904)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.1 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.0 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.0 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.0 GO:0051695 actin filament uncapping(GO:0051695)
0.0 0.0 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.0 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.0 0.0 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.1 GO:0035826 rubidium ion transport(GO:0035826)
0.0 0.1 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.0 GO:0035106 operant conditioning(GO:0035106)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.0 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:1990622 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.0 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.0 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.4 GO:0019767 IgE receptor activity(GO:0019767)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.2 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368)
0.1 0.3 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.2 GO:0015137 citrate transmembrane transporter activity(GO:0015137)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0034235 GPI-anchor transamidase activity(GO:0003923) GPI anchor binding(GO:0034235)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.0 GO:0051903 all-trans retinal binding(GO:0005503) benzaldehyde dehydrogenase activity(GO:0019115) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0050700 peptidoglycan binding(GO:0042834) CARD domain binding(GO:0050700)
0.0 0.0 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.0 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.0 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)