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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Zfp423

Z-value: 0.30

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Transcription factors associated with Zfp423

Gene Symbol Gene ID Gene Info
ENSRNOG00000014658 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp423rn6_v1_chr19_+_20147037_201470370.941.6e-02Click!

Activity profile of Zfp423 motif

Sorted Z-values of Zfp423 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_77945016 0.19 ENSRNOT00000076223
zinc finger protein 37
chr10_-_18131562 0.12 ENSRNOT00000006676
T-cell leukemia, homeobox 3
chr1_+_266953139 0.11 ENSRNOT00000054696
neuralized E3 ubiquitin protein ligase 1
chr4_+_142453013 0.11 ENSRNOT00000056573

chr12_-_47793534 0.10 ENSRNOT00000001588
family with sequence similarity 222, member A
chr1_-_198316882 0.09 ENSRNOT00000085304
ENSRNOT00000064985
TAO kinase 2
chr7_+_130532435 0.08 ENSRNOT00000092672
ENSRNOT00000092535
SH3 and multiple ankyrin repeat domains 3
chr1_-_259484569 0.08 ENSRNOT00000021289
ENSRNOT00000021114
ENSRNOT00000021229
ENSRNOT00000021347
ENSRNOT00000021226
sorbin and SH3 domain containing 1
chr19_+_55094585 0.07 ENSRNOT00000068452
zinc finger protein, multitype 1
chr7_+_120067379 0.06 ENSRNOT00000011270
CDC42 effector protein 1
chr15_-_28733513 0.06 ENSRNOT00000078180
spalt-like transcription factor 2
chr4_-_156427755 0.06 ENSRNOT00000085675
ENSRNOT00000014030
peroxisomal targeting signal 1 receptor-like
chr4_-_157008947 0.06 ENSRNOT00000073341
peroxisomal biogenesis factor 5
chr1_+_198932870 0.06 ENSRNOT00000055003
fibrosin
chr13_-_90710148 0.06 ENSRNOT00000010113
ENSRNOT00000080638
potassium voltage-gated channel subfamily J member 9
chr1_-_226924244 0.05 ENSRNOT00000028971
transmembrane protein 132A
chr1_-_225948626 0.05 ENSRNOT00000077823
inner centromere protein
chr1_-_226152524 0.05 ENSRNOT00000027756
fatty acid desaturase 2
chr1_+_40529045 0.04 ENSRNOT00000026564
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr13_+_51384562 0.04 ENSRNOT00000077928
lysine demethylase 5B
chr15_-_52210746 0.04 ENSRNOT00000046054
bone morphogenetic protein 1
chr7_-_144960527 0.03 ENSRNOT00000086554
zinc finger protein 385A
chr19_-_55490426 0.03 ENSRNOT00000081800
CBFA2/RUNX1 translocation partner 3
chr7_-_14189688 0.03 ENSRNOT00000037456
notch 3
chr16_-_74264142 0.03 ENSRNOT00000026067
dickkopf WNT signaling pathway inhibitor 4
chr1_-_131454689 0.03 ENSRNOT00000014152
nuclear receptor subfamily 2, group F, member 2
chr12_-_17358617 0.02 ENSRNOT00000001733
G protein-coupled receptor 146
chr13_+_35554964 0.02 ENSRNOT00000072632
transmembrane protein 185B
chr7_-_3074359 0.02 ENSRNOT00000019738
IKAROS family zinc finger 4
chr2_-_210413985 0.02 ENSRNOT00000025036
striatin interacting protein 1
chr3_+_56868167 0.02 ENSRNOT00000087134
glutamate decarboxylase 1
chrX_+_140878216 0.02 ENSRNOT00000075840
ENSRNOT00000077026
Zic family member 3
chr6_-_44361908 0.02 ENSRNOT00000009491
inhibitor of DNA binding 2, HLH protein
chr9_+_53120656 0.02 ENSRNOT00000043714
PMS1 homolog 1, mismatch repair system component
chr1_-_101856881 0.01 ENSRNOT00000028615
glutamate ionotropic receptor NMDA type subunit 2D
chr7_-_70926903 0.01 ENSRNOT00000031005
LDL receptor related protein 1
chr8_+_82038967 0.01 ENSRNOT00000079535
myosin VA
chr10_+_80790168 0.01 ENSRNOT00000073315
ENSRNOT00000075163
carbonic anhydrase 10
chr1_-_170464341 0.01 ENSRNOT00000024850
tripartite motif-containing 3
chr16_+_47665816 0.01 ENSRNOT00000030519
CDKN2A interacting protein
chrX_-_72515320 0.01 ENSRNOT00000076725
phosphorylase kinase, alpha 1
chr3_-_122920684 0.01 ENSRNOT00000028818
carboxypeptidase X (M14 family), member 1
chr1_-_82546937 0.01 ENSRNOT00000028100
heterogeneous nuclear ribonucleoprotein U-like 1
chr2_-_61949926 0.01 ENSRNOT00000025966
natriuretic peptide receptor 3
chr1_+_226091774 0.01 ENSRNOT00000027693
fatty acid desaturase 3
chr10_-_104097812 0.01 ENSRNOT00000004867
small ubiquitin-like modifier 2
chr9_+_117538346 0.01 ENSRNOT00000022849
erythrocyte membrane protein band 4.1-like 3
chr4_-_157009674 0.00 ENSRNOT00000071625
peroxisomal biogenesis factor 5
chr7_-_11444786 0.00 ENSRNOT00000027323
zinc finger and BTB domain containing 7a
chr19_-_11057254 0.00 ENSRNOT00000025559
homocysteine inducible ER protein with ubiquitin like domain 1
chr5_+_138279506 0.00 ENSRNOT00000084651
prolyl 3-hydroxylase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp423

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0090202 mitral valve formation(GO:0003192) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.1 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:1904008 response to monosodium glutamate(GO:1904008)
0.0 0.0 GO:0015942 formate metabolic process(GO:0015942)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.0 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)