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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Zfp384
Z-value: 0.88
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Transcription factors associated with Zfp384
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zfp384 | rn6_v1_chr4_+_157538303_157538303 | -0.61 | 2.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_+_24242642 Show fit | 0.43 |
ENSRNOT00000024323
|
ring finger protein 182 |
|
| chr15_-_23969011 Show fit | 0.32 |
ENSRNOT00000014821
|
GTP cyclohydrolase 1 |
|
| chr1_+_218466289 Show fit | 0.32 |
ENSRNOT00000017948
|
MAS related GPR family member F |
|
| chr4_+_438668 Show fit | 0.32 |
ENSRNOT00000008951
|
engrailed homeobox 2 |
|
| chr14_-_91996774 Show fit | 0.29 |
ENSRNOT00000005851
|
dopa decarboxylase |
|
| chr4_-_482645 Show fit | 0.27 |
ENSRNOT00000062073
ENSRNOT00000071713 |
canopy FGF signaling regulator 1 |
|
| chr15_-_34550850 Show fit | 0.27 |
ENSRNOT00000027794
ENSRNOT00000090228 |
cerebellin 3 precursor |
|
| chr12_-_38782010 Show fit | 0.27 |
ENSRNOT00000001813
|
WD repeat domain 66 |
|
| chr13_+_36532758 Show fit | 0.21 |
ENSRNOT00000083007
|
engrailed 1 |
|
| chr18_-_5314511 Show fit | 0.20 |
ENSRNOT00000022637
ENSRNOT00000079682 |
zinc finger protein 521 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Zfp384
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.1 | 0.3 | GO:0014916 | regulation of lung blood pressure(GO:0014916) |
| 0.1 | 0.3 | GO:0052314 | phytoalexin metabolic process(GO:0052314) |
| 0.0 | 0.3 | GO:0019585 | uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) |
| 0.0 | 0.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.3 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.0 | 0.3 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.1 | 0.2 | GO:0039020 | regulation of pronephros size(GO:0035565) pronephric nephron tubule development(GO:0039020) hepatoblast differentiation(GO:0061017) |
| 0.1 | 0.2 | GO:0035470 | positive regulation of vascular wound healing(GO:0035470) |
| 0.1 | 0.2 | GO:0001788 | antibody-dependent cellular cytotoxicity(GO:0001788) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.7 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.3 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.0 | 0.3 | GO:0045275 | respiratory chain complex III(GO:0045275) |
| 0.0 | 0.3 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.0 | 0.2 | GO:0072557 | IPAF inflammasome complex(GO:0072557) |
| 0.0 | 0.2 | GO:1903349 | omegasome membrane(GO:1903349) omegasome(GO:1990462) |
| 0.0 | 0.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.2 | GO:0042555 | MCM complex(GO:0042555) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.4 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.1 | 0.3 | GO:0004058 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
| 0.0 | 0.3 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.0 | 0.3 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.3 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 0.3 | GO:0003954 | NADH dehydrogenase activity(GO:0003954) |
| 0.0 | 0.3 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 0.2 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 0.0 | 0.2 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.0 | 0.0 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.0 | 0.0 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 0.0 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.0 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.0 | 0.0 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 0.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 0.6 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.4 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 0.3 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 0.3 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 0.3 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 0.3 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.0 | 0.3 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.2 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |