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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Zfp110

Z-value: 2.03

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Transcription factors associated with Zfp110

Gene Symbol Gene ID Gene Info
Zfp110
ENSRNOG00000031328 zinc finger protein 110

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp110rn6_v1_chr1_-_65756528_657565280.983.9e-03Click!

Activity profile of Zfp110 motif

Sorted Z-values of Zfp110 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_37185548 4.40 ENSRNOT00000001338
LOC102556092
uncharacterized LOC102556092
chr1_+_80973739 3.50 ENSRNOT00000026088
ENSRNOT00000081983
AC118165.1

chr1_-_88558696 3.16 ENSRNOT00000038642
AABR07002896.1

chr10_-_74769637 3.06 ENSRNOT00000008889
LOC102555183
zinc finger protein OZF-like
chr1_-_87777668 2.66 ENSRNOT00000037288
AABR07002870.1

chr1_-_62316450 2.53 ENSRNOT00000079171
AABR07001926.3

chr16_-_21473808 1.97 ENSRNOT00000066776
Zfp964
zinc finger protein 964
chr14_+_6298872 1.91 ENSRNOT00000065071
Znf442
zinc finger protein 442
chr7_-_9976367 1.80 ENSRNOT00000044241
Zfp347
zinc finger protein 347
chr7_-_15821927 1.74 ENSRNOT00000050658
LOC691422
similar to zinc finger protein 101
chr5_-_164648328 1.69 ENSRNOT00000090811
Zfp933
zinc finger protein 933
chr7_+_15279611 1.36 ENSRNOT00000043826
Zfp952
zinc finger protein 952
chr1_-_199061107 1.13 ENSRNOT00000085954
Zfp689
zinc finger protein 689
chr1_-_87777359 1.07 ENSRNOT00000074090
AABR07002870.1

chr1_+_84758233 1.06 ENSRNOT00000072734
AABR07002775.1

chr1_-_88558387 1.04 ENSRNOT00000074174
AABR07002896.1

chr1_+_88542035 1.01 ENSRNOT00000032973
Zfp420
zinc finger protein 420
chr15_-_30147793 0.99 ENSRNOT00000060399
AABR07017693.1

chr1_+_88451958 0.82 ENSRNOT00000074301
LOC102549115
zinc finger protein 260-like
chr2_+_230901126 0.72 ENSRNOT00000016026
ENSRNOT00000015564
ENSRNOT00000068198
Camk2d
calcium/calmodulin-dependent protein kinase II delta
chr15_-_48445588 0.68 ENSRNOT00000077197
ENSRNOT00000018583
Extl3
exostosin-like glycosyltransferase 3
chr9_+_50892605 0.63 ENSRNOT00000033133
Bivm
basic, immunoglobulin-like variable motif containing
chr8_+_131965134 0.61 ENSRNOT00000078308
Znf660
zinc finger protein 660
chr16_-_19583386 0.57 ENSRNOT00000090131
Zfp617
zinc finger protein 617
chr1_+_61374379 0.51 ENSRNOT00000015343
Zfp53
zinc finger protein 53
chr5_-_113939127 0.50 ENSRNOT00000039554
Mysm1
myb-like, SWIRM and MPN domains 1
chr19_-_37907714 0.44 ENSRNOT00000026361
Ctrl
chymotrypsin-like
chr1_-_65611815 0.43 ENSRNOT00000036874
Zfp324
zinc finger protein 324
chr3_-_105663457 0.39 ENSRNOT00000067646
Zfp770
zinc finger protein 770
chr13_-_98078946 0.37 ENSRNOT00000035875
Ahctf1
AT hook containing transcription factor 1
chr1_-_61872975 0.34 ENSRNOT00000078809
AABR07001910.1

chr1_+_84652632 0.31 ENSRNOT00000041861
AABR07002774.2

chr18_+_79813759 0.27 ENSRNOT00000021768
Zfp516
zinc finger protein 516
chr1_-_101323960 0.27 ENSRNOT00000041513
Trpm4
transient receptor potential cation channel, subfamily M, member 4
chr1_-_282492912 0.23 ENSRNOT00000047883
AABR07007130.1

chr4_+_149908375 0.23 ENSRNOT00000019504
LOC100909657
uncharacterized LOC100909657
chr18_-_76653056 0.22 ENSRNOT00000078496
Adnp2
ADNP homeobox 2
chr4_+_49369296 0.21 ENSRNOT00000007822
Wnt16
wingless-type MMTV integration site family, member 16
chrX_+_43535737 0.21 ENSRNOT00000087073
LOC102557137
E3 ubiquitin-protein ligase RNF168-like
chr10_+_59533480 0.20 ENSRNOT00000087723
Atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr1_-_62558033 0.20 ENSRNOT00000015520
Zfp40
zinc finger protein 40
chr7_-_15852930 0.16 ENSRNOT00000009270
LOC691422
similar to zinc finger protein 101
chr10_-_70172739 0.16 ENSRNOT00000010015
Rffl
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chrX_-_62698830 0.15 ENSRNOT00000076359
Pola1
DNA polymerase alpha 1, catalytic subunit
chr2_+_22950018 0.15 ENSRNOT00000071804
Homer1
homer scaffolding protein 1
chr10_+_29606748 0.13 ENSRNOT00000080720
AABR07029467.2

chr7_-_120518653 0.13 ENSRNOT00000016362
Baiap2l2
BAI1-associated protein 2-like 2
chr7_+_116655145 0.13 ENSRNOT00000009823
Zfp41
zinc finger protein 41
chr1_-_199655147 0.12 ENSRNOT00000026979
LOC103691238
zinc finger protein 239-like
chr3_-_8979889 0.10 ENSRNOT00000065128
Crat
carnitine O-acetyltransferase
chr20_+_4369178 0.09 ENSRNOT00000088079
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr9_-_120101098 0.08 ENSRNOT00000002917
Fam114a1l1
family with sequence similarity 114, member A1-like 1
chr14_+_71424083 0.08 ENSRNOT00000004274
Tapt1
transmembrane anterior posterior transformation 1
chr5_-_99566317 0.07 ENSRNOT00000051028
ENSRNOT00000089235
Mpdz
multiple PDZ domain crumbs cell polarity complex component
chr17_+_36690249 0.06 ENSRNOT00000089476
ENSRNOT00000082140
LOC688583
similar to High mobility group protein 4 (HMG-4) (High mobility group protein 2a) (HMG-2a)
chr2_+_264864351 0.03 ENSRNOT00000015434
Lrrc40
leucine rich repeat containing 40
chr1_-_72468738 0.03 ENSRNOT00000029136
Zfp628
zinc finger protein 628
chr14_-_45002719 0.03 ENSRNOT00000002883
Fam114a1
family with sequence similarity 114, member A1
chr12_-_11157583 0.02 ENSRNOT00000082535
Zkscan5
zinc finger with KRAB and SCAN domains 5
chr11_+_85508300 0.02 ENSRNOT00000038646
AABR07034730.3

chr4_+_110699557 0.01 ENSRNOT00000030588
ENSRNOT00000092261
Lrrtm4
leucine rich repeat transmembrane neuronal 4
chrX_-_77295426 0.00 ENSRNOT00000090833
Taf9b
TATA-box binding protein associated factor 9b

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp110

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.5 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.3 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 1.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.7 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0034706 sodium channel complex(GO:0034706)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 13.2 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway