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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Zbtb4

Z-value: 0.48

Motif logo

Transcription factors associated with Zbtb4

Gene Symbol Gene ID Gene Info
ENSRNOG00000014689 zinc finger and BTB domain containing 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb4rn6_v1_chr10_+_56381813_56381813-0.672.2e-01Click!

Activity profile of Zbtb4 motif

Sorted Z-values of Zbtb4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_45815940 0.35 ENSRNOT00000073276
G protein-coupled receptor 6
chrX_+_136460215 0.17 ENSRNOT00000093538
Rho GTPase activating protein 36
chr1_-_80783898 0.14 ENSRNOT00000045306
carcinoembryonic antigen-related cell adhesion molecule 16
chr2_-_195888216 0.14 ENSRNOT00000056436
tuftelin 1
chr4_+_114935970 0.13 ENSRNOT00000082336
solute carrier family 4 member 5
chr10_-_90049112 0.13 ENSRNOT00000028323
peptide YY (mapped)
chr4_+_154309426 0.12 ENSRNOT00000019346
alpha-2-macroglobulin
chr7_-_130350570 0.12 ENSRNOT00000055805
outer dense fiber of sperm tails 3B
chr8_-_55491152 0.12 ENSRNOT00000014965
rCG58364-like
chr7_+_13062196 0.11 ENSRNOT00000000193
phospholipid phosphatase 2
chr3_+_65815080 0.10 ENSRNOT00000006429
ubiquitin-conjugating enzyme E2E 3
chr20_+_2004052 0.10 ENSRNOT00000001008
myelin oligodendrocyte glycoprotein
chr2_+_211930326 0.10 ENSRNOT00000027765
solute carrier family 25 member 24
chr9_-_64096265 0.09 ENSRNOT00000013502
tRNA-yW synthesizing protein 5
chr11_+_32211115 0.09 ENSRNOT00000087452
mitochondrial ribosomal protein S6
chr2_+_211337271 0.08 ENSRNOT00000045155
cytochrome c oxidase subunit 6B1
chr7_-_115979298 0.08 ENSRNOT00000075883
similar to secreted Ly6/uPAR related protein 2
chr8_-_6235967 0.08 ENSRNOT00000068290
hypothetical protein LOC654482
chr10_+_56445647 0.08 ENSRNOT00000056870
transmembrane protein 256
chr8_+_65686648 0.08 ENSRNOT00000017233
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr13_-_102721218 0.08 ENSRNOT00000005459
mitochondrial amidoxime reducing component 1
chr16_+_69048730 0.08 ENSRNOT00000086082
ENSRNOT00000078128
RAB11 family interacting protein 1
chr5_+_138154673 0.08 ENSRNOT00000064452
solute carrier family 2 member 1
chr6_+_95826546 0.08 ENSRNOT00000043587

chr1_-_91588609 0.07 ENSRNOT00000050931
small nuclear ribonucleoprotein polypeptide G
chr2_+_84678948 0.07 ENSRNOT00000046325
family with sequence similarity 173, member B
chr8_-_111965889 0.07 ENSRNOT00000032376
beaded filament structural protein 2
chr1_+_240908483 0.07 ENSRNOT00000019367
Kruppel-like factor 9
chr3_-_9738752 0.07 ENSRNOT00000045993
prostaglandin E synthase
chr14_+_89314176 0.07 ENSRNOT00000006765
uridine phosphorylase 1
chr15_-_52332097 0.07 ENSRNOT00000017723
fibroblast growth factor 17
chr4_-_84768249 0.07 ENSRNOT00000013205
FK506 binding protein 14
chr5_+_159845774 0.07 ENSRNOT00000012328
Eph receptor A2
chr15_-_61564695 0.07 ENSRNOT00000068216
regulator of cell cycle
chr1_-_162385575 0.06 ENSRNOT00000016540
thyroid hormone responsive
chr3_-_15433252 0.06 ENSRNOT00000008817
LIM homeobox 6
chr5_-_16706909 0.06 ENSRNOT00000011314
ribosomal protein S20
chr1_+_193335645 0.06 ENSRNOT00000019640
leucine carboxyl methyltransferase 1
chr11_+_81358592 0.06 ENSRNOT00000002487
replication factor C subunit 4
chr4_+_154423209 0.06 ENSRNOT00000075799
alpha-2-macroglobulin-like
chr20_+_3556975 0.06 ENSRNOT00000089417
discoidin domain receptor tyrosine kinase 1
chr1_-_83977236 0.05 ENSRNOT00000028434
egl-9 family hypoxia-inducible factor 2
chr7_+_10962330 0.05 ENSRNOT00000008360
transducin-like enhancer of split 6
chr8_-_53362006 0.05 ENSRNOT00000077145
claudin 25-like
chr19_+_33928356 0.05 ENSRNOT00000058162
endothelin receptor type A
chr5_-_136721379 0.05 ENSRNOT00000026704
ATPase H+ transporting V0 subunit B
chr5_+_126812187 0.05 ENSRNOT00000057372
low density lipoprotein receptor class A domain containing 1
chr5_-_50193571 0.05 ENSRNOT00000051243
cilia and flagella associated protein 206
chr9_+_101284902 0.05 ENSRNOT00000065533
sialidase 4
chr18_-_55859333 0.05 ENSRNOT00000025989
myozenin 3
chr7_+_122700854 0.05 ENSRNOT00000086603
ring-box 1
chr5_+_48011864 0.05 ENSRNOT00000067610
midasin AAA ATPase 1
chr9_+_10535340 0.05 ENSRNOT00000075408
zinc and ring finger 4
chr2_+_187218851 0.05 ENSRNOT00000017798
SH2 domain containing 2A
chr1_+_7101715 0.05 ENSRNOT00000019994
splicing factor 3b, subunit 5
chrX_+_124516949 0.05 ENSRNOT00000051474
ring finger protein 113A1
chr7_-_59514939 0.05 ENSRNOT00000085579
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr15_+_52241801 0.05 ENSRNOT00000082639
HR, lysine demethylase and nuclear receptor corepressor
chr2_-_84678790 0.05 ENSRNOT00000015886
chaperonin containing TCP1 subunit 5
chr5_+_79179417 0.05 ENSRNOT00000010454
orosomucoid 1
chr10_-_45851984 0.05 ENSRNOT00000058308
zinc finger protein 496
chr15_+_61879184 0.05 ENSRNOT00000042606
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr5_+_169364306 0.05 ENSRNOT00000014213
acyl-CoA thioesterase 7
chr19_+_16417817 0.04 ENSRNOT00000015272
iroquois homeobox 5
chr4_-_171176581 0.04 ENSRNOT00000030850
RAS-like, estrogen-regulated, growth-inhibitor
chr2_-_187622373 0.04 ENSRNOT00000026396
Rh family B glycoprotein
chrX_+_143097525 0.04 ENSRNOT00000004559
coagulation factor IX
chr1_+_189870622 0.04 ENSRNOT00000075003
transmembrane protein 159
chr9_+_80118029 0.04 ENSRNOT00000023068
insulin-like growth factor binding protein 2
chr5_+_152559577 0.04 ENSRNOT00000082245
solute carrier family 30 member 2
chr10_-_62032400 0.04 ENSRNOT00000086378
ENSRNOT00000004161
diphthamide biosynthesis 1
chr16_+_74292438 0.04 ENSRNOT00000026197
voltage-dependent anion channel 3
chrX_+_123404518 0.04 ENSRNOT00000015085
solute carrier family 25 member 5
chr8_+_13796021 0.04 ENSRNOT00000013927
V-set and transmembrane domain containing 5
chr19_+_52374298 0.04 ENSRNOT00000092131
ATPase secretory pathway Ca2+ transporting 2
chr10_-_49196177 0.04 ENSRNOT00000084418
zinc finger protein 286A
chr1_-_225631468 0.04 ENSRNOT00000072579

chr12_+_12227010 0.04 ENSRNOT00000060843
ENSRNOT00000092610
BAI1-associated protein 2-like 1
chr3_+_46286712 0.04 ENSRNOT00000085563
membrane associated ring-CH-type finger 7
chr4_-_123494742 0.04 ENSRNOT00000073268
solute carrier family 41, member 3
chr11_-_45510961 0.04 ENSRNOT00000002238
translocase of outer mitochondrial membrane 70
chr1_-_101741441 0.04 ENSRNOT00000028570
sulfotransferase family 2B member 1
chr12_+_52452273 0.04 ENSRNOT00000056680
ENSRNOT00000088381
peroxisomal membrane protein 2
chrX_+_20351486 0.04 ENSRNOT00000093675
ENSRNOT00000047444
WNK lysine deficient protein kinase 3
chr18_+_70263359 0.04 ENSRNOT00000019573
cilia and flagella associated protein 53
chr17_-_9441526 0.04 ENSRNOT00000000146
thioredoxin domain containing 15
chr4_+_7282948 0.03 ENSRNOT00000011052
cyclin-dependent kinase 5
chr10_+_47282208 0.03 ENSRNOT00000057953
potassium voltage-gated channel subfamily J member 12
chr7_+_12179203 0.03 ENSRNOT00000049170
methyl-CpG binding domain protein 3
chr4_-_115239723 0.03 ENSRNOT00000042699
actin, gamma 2, smooth muscle, enteric
chr9_-_121972055 0.03 ENSRNOT00000089735
clusterin-like protein 1
chr1_-_263803150 0.03 ENSRNOT00000017840
cytochrome P450, family 2, subfamily c, polypeptide 23
chr1_-_100537377 0.03 ENSRNOT00000026599
Spi-B transcription factor
chr20_-_2040422 0.03 ENSRNOT00000052311
RT1 class Ib, locus M5
chr20_+_17750744 0.03 ENSRNOT00000000745
similar to RIKEN cDNA 1700049L16
chr1_-_214511529 0.03 ENSRNOT00000026390
chitinase domain containing 1
chr1_+_101704746 0.03 ENSRNOT00000028564
family with sequence similarity 83, member E
chr6_+_137210052 0.03 ENSRNOT00000031788
ENSRNOT00000065213
SIVA1, apoptosis-inducing factor
chr16_+_56247659 0.03 ENSRNOT00000017452
tumor suppressor candidate 3
chr1_-_53038229 0.03 ENSRNOT00000017282
mitochondrial pyruvate carrier 1
chr1_-_81412251 0.03 ENSRNOT00000026946
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr10_-_38969501 0.03 ENSRNOT00000090691
ENSRNOT00000081309
ENSRNOT00000010029
interleukin 4
chr4_-_80367606 0.03 ENSRNOT00000014331
similar to RIKEN cDNA 4921507P07
chr5_-_131860637 0.03 ENSRNOT00000064569
ENSRNOT00000080242
solute carrier family 5 member 9
chr1_-_266142538 0.03 ENSRNOT00000026792
ARP1 actin-related protein 1 homolog A, centractin alpha
chr8_+_114897011 0.03 ENSRNOT00000074683
twinfilin actin-binding protein 2
chr13_+_78805347 0.03 ENSRNOT00000003748
serpin family C member 1
chr18_-_51651267 0.03 ENSRNOT00000020325
aldehyde dehydrogenase 7 family, member A1
chr8_-_126495347 0.03 ENSRNOT00000013467
C-x(9)-C motif containing 1
chr9_-_65879521 0.03 ENSRNOT00000017517
amyotrophic lateral sclerosis 2 chromosome region, candidate 11
chr4_-_155631856 0.03 ENSRNOT00000088270
solute carrier family 2 member 3
chr10_+_13061170 0.03 ENSRNOT00000004936
protein kinase, membrane associated tyrosine/threonine 1
chr19_-_869490 0.03 ENSRNOT00000080433
CKLF-like MARVEL transmembrane domain containing 1
chrX_+_114929029 0.03 ENSRNOT00000006459
p21 (RAC1) activated kinase 3
chr18_+_29506128 0.03 ENSRNOT00000003878
solute carrier family 35, member A4
chr7_+_36826360 0.03 ENSRNOT00000029783
NADH:ubiquinone oxidoreductase subunit A13
chr1_-_102970950 0.03 ENSRNOT00000018194
tumor susceptibility 101
chr1_+_197813963 0.03 ENSRNOT00000045531
ribosomal protein L36-like
chr16_+_56248331 0.03 ENSRNOT00000085300
tumor suppressor candidate 3
chr1_+_224970807 0.03 ENSRNOT00000026141
transmembrane protein 223
chr18_+_73645907 0.03 ENSRNOT00000023487
lipoxygenase homology domains 1
chr9_+_64095978 0.03 ENSRNOT00000021533
matrix AAA peptidase interacting protein 1
chr7_+_12247498 0.02 ENSRNOT00000022358
proprotein convertase subtilisin/kexin type 4
chr14_-_18849258 0.02 ENSRNOT00000033406
platelet factor 4
chr1_-_214074663 0.02 ENSRNOT00000026215
chitinase domain-containing protein 1-like
chr1_-_100980340 0.02 ENSRNOT00000064272
protein arginine methyltransferase 1
chr16_-_7007287 0.02 ENSRNOT00000041216
inter-alpha trypsin inhibitor, heavy chain 3
chr1_+_85496937 0.02 ENSRNOT00000076809
ENSRNOT00000087175
selenoprotein V
chr7_-_119716238 0.02 ENSRNOT00000075678
interleukin 2 receptor subunit beta
chr7_-_138707221 0.02 ENSRNOT00000009199
adhesion molecule with Ig like domain 2
chr1_-_170397191 0.02 ENSRNOT00000090181
amyloid beta precursor protein binding family B member 1
chr5_+_19471664 0.02 ENSRNOT00000013563
syndecan binding protein
chr7_-_123156558 0.02 ENSRNOT00000005943
RNA polymerase III subunit H
chr17_+_23986758 0.02 ENSRNOT00000024066
sirtuin 5
chr10_+_49299125 0.02 ENSRNOT00000074853
trans-golgi network vesicle protein 23 homolog B
chr7_+_138707426 0.02 ENSRNOT00000037874
PC-esterase domain containing 1B
chr1_-_198128857 0.02 ENSRNOT00000026496
coronin 1A
chr5_+_58151985 0.02 ENSRNOT00000020885
interleukin 11 receptor subunit alpha 1
chr19_+_61677542 0.02 ENSRNOT00000014785
integrin subunit beta 1
chr3_+_55369214 0.02 ENSRNOT00000067161
nitric oxide synthase trafficking
chr10_-_105228547 0.02 ENSRNOT00000028875
signal recognition particle 68
chr4_+_61924013 0.02 ENSRNOT00000090717
bisphosphoglycerate mutase
chr8_+_59111271 0.02 ENSRNOT00000029413
SH2 domain containing 7
chr3_-_2456041 0.02 ENSRNOT00000062001
ring finger protein 224
chr4_-_58875753 0.02 ENSRNOT00000016991
podocalyxin-like
chr9_+_42871950 0.02 ENSRNOT00000089673
AT-rich interaction domain 5A
chr12_-_40680374 0.02 ENSRNOT00000048984
ENSRNOT00000080418
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chr8_+_81766041 0.02 ENSRNOT00000032280
one cut homeobox 1
chr19_-_19727081 0.02 ENSRNOT00000020700
adenylate cyclase 7
chr17_+_77224112 0.02 ENSRNOT00000024178
minichromosome maintenance 10 replication initiation factor
chr7_+_11992543 0.02 ENSRNOT00000024576
abhydrolase domain containing 17A
chr12_+_40553741 0.02 ENSRNOT00000057396
rCG21419-like
chr14_+_43810119 0.02 ENSRNOT00000003327
RNA binding motif protein 47
chrX_+_32495809 0.01 ENSRNOT00000020999
similar to RIKEN cDNA 1700045I19
chr2_+_157316266 0.01 ENSRNOT00000015387
TCDD-inducible poly(ADP-ribose) polymerase
chr3_+_93968855 0.01 ENSRNOT00000014478
F-box protein 3
chr3_-_161322289 0.01 ENSRNOT00000022594
phospholipid transfer protein
chr12_+_41281559 0.01 ENSRNOT00000049622
ENSRNOT00000057266
2'-5' oligoadenylate synthetase 1E
chr11_-_76804510 0.01 ENSRNOT00000002649
coiled-coil domain containing 50
chr8_-_48692295 0.01 ENSRNOT00000065456
VPS11 CORVET/HOPS core subunit
chr2_-_210738378 0.01 ENSRNOT00000025746
glutathione S-transferase, mu 6
chr7_-_12918173 0.01 ENSRNOT00000011010
tubulin polyglutamylase complex subunit 1
chr11_+_87220618 0.01 ENSRNOT00000041975
goosecoid homeobox 2
chr14_+_21041621 0.01 ENSRNOT00000086571
G-rich RNA sequence binding factor 1
chr1_-_220771181 0.01 ENSRNOT00000027811
squamous cell carcinoma antigen recognized by T cells 1
chr3_-_14386118 0.01 ENSRNOT00000025649
RAB14, member RAS oncogene family
chr4_+_158224000 0.01 ENSRNOT00000084240
ENSRNOT00000078495
anoctamin 2
chr13_-_77959089 0.01 ENSRNOT00000003586
calcyclin binding protein
chr8_+_21905865 0.01 ENSRNOT00000027973
peter pan homolog (Drosophila)
chrX_+_63343546 0.01 ENSRNOT00000076315
kelch-like family member 15
chr7_+_121480723 0.01 ENSRNOT00000065304
activating transcription factor 4
chr3_+_171743929 0.01 ENSRNOT00000079113
ENSRNOT00000064400
RAB22A, member RAS oncogene family
chrX_-_10772633 0.01 ENSRNOT00000035153
ubiquitin-conjugating enzyme E2Q family member 2-like
chr7_-_130347587 0.01 ENSRNOT00000040541
thymidine phosphorylase
chr7_-_122967178 0.01 ENSRNOT00000052098
RAN GTPase activating protein 1
chr13_-_93746994 0.01 ENSRNOT00000005072
opsin 3
chr18_-_27725694 0.01 ENSRNOT00000026398
eukaryotic translation termination factor 1
chr1_-_216703534 0.01 ENSRNOT00000027972
pleckstrin homology-like domain, family A, member 2
chrX_+_29525256 0.01 ENSRNOT00000050018
RAB9A, member RAS oncogene family
chr18_+_29110242 0.01 ENSRNOT00000025756
purine rich element binding protein A
chr3_+_161343883 0.01 ENSRNOT00000023202
PDX1 C-terminal inhibiting factor 1
chr12_+_10254951 0.01 ENSRNOT00000061129
G protein-coupled receptor 12
chr20_+_46250363 0.01 ENSRNOT00000076522
ENSRNOT00000000334
CD164 molecule
chr1_+_153589471 0.01 ENSRNOT00000023205
frizzled class receptor 4
chr8_+_82257849 0.01 ENSRNOT00000011963
ENSRNOT00000075708
G protein subunit beta 5
chr15_-_42751330 0.01 ENSRNOT00000066478
ADAM metallopeptidase domain 2
chr3_+_47439076 0.01 ENSRNOT00000011794
TRAF family member-associated NFKB activator
chr5_-_59292944 0.01 ENSRNOT00000051234
olfactory receptor 838
chr1_+_213766758 0.01 ENSRNOT00000005645
interferon induced transmembrane protein 1
chr5_+_48047913 0.01 ENSRNOT00000065926
LYR motif containing 2
chr9_-_99299715 0.01 ENSRNOT00000027622
histone deacetylase 4
chr16_-_7007051 0.01 ENSRNOT00000023984
inter-alpha trypsin inhibitor, heavy chain 3
chr7_-_119623072 0.01 ENSRNOT00000050511
thiosulfate sulfurtransferase
chrX_-_4945944 0.01 ENSRNOT00000077238
lysine demethylase 6A
chr1_+_143036218 0.01 ENSRNOT00000025797
phosphodiesterase 8A
chr16_+_20426566 0.00 ENSRNOT00000026225
IFI30, lysosomal thiol reductase
chr18_+_31444472 0.00 ENSRNOT00000075159
ring finger protein 14
chr1_+_56982821 0.00 ENSRNOT00000059845
ER membrane-associated RNA degradation
chr1_+_142136452 0.00 ENSRNOT00000016445
HD domain containing 3
chr19_+_38846201 0.00 ENSRNOT00000030768
ENSRNOT00000063977
transport and golgi organization 6 homolog

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990402 embryonic liver development(GO:1990402)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0015866 ADP transport(GO:0015866)
0.0 0.0 GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.0 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112) fatty-acyl-CoA catabolic process(GO:0036115)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.0 GO:2000688 positive regulation of rubidium ion transport(GO:2000682) positive regulation of rubidium ion transmembrane transporter activity(GO:2000688)
0.0 0.1 GO:0044206 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) pyrimidine ribonucleoside catabolic process(GO:0046133)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0032426 stereocilium tip(GO:0032426)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0008940 nitrate reductase activity(GO:0008940)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0005111 type 1 fibroblast growth factor receptor binding(GO:0005105) type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)