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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Zbtb33_Chd2
Z-value: 1.21
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Transcription factors associated with Zbtb33_Chd2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Chd2 | rn6_v1_chr1_-_134870255_134870255 | -0.44 | 4.6e-01 | Click! |
| Zbtb33 | rn6_v1_chrX_+_124393332_124393332 | -0.08 | 9.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_19652898 Show fit | 0.56 |
ENSRNOT00000009648
|
spindle apparatus coiled-coil protein 1 |
|
| chr6_+_144291974 Show fit | 0.44 |
ENSRNOT00000035255
|
non-SMC condensin II complex, subunit G2 |
|
| chr12_+_23954574 Show fit | 0.44 |
ENSRNOT00000046343
|
serine/threonine/tyrosine interacting-like 1 |
|
| chr1_+_280103695 Show fit | 0.42 |
ENSRNOT00000065289
|
enolase family member 4 |
|
| chr1_+_205706468 Show fit | 0.41 |
ENSRNOT00000089957
ENSRNOT00000023877 |
erythroid differentiation regulatory factor 1 |
|
| chr6_+_49529669 Show fit | 0.40 |
ENSRNOT00000079520
|
transmembrane protein 18 |
|
| chr18_+_52917124 Show fit | 0.38 |
ENSRNOT00000021921
|
solute carrier family 12 member 2 |
|
| chr6_+_49529228 Show fit | 0.32 |
ENSRNOT00000006836
|
transmembrane protein 18 |
|
| chr3_-_151724654 Show fit | 0.31 |
ENSRNOT00000026964
|
RNA binding motif protein 39 |
|
| chr8_-_79119720 Show fit | 0.29 |
ENSRNOT00000086562
|
testis expressed 9 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Zbtb33_Chd2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.0 | 0.5 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.1 | 0.4 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 0.0 | 0.4 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.1 | 0.3 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 0.0 | 0.3 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.0 | 0.3 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.0 | 0.3 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.1 | 0.2 | GO:0060825 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) |
| 0.1 | 0.2 | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 0.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 0.4 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 0.4 | GO:0000796 | condensin complex(GO:0000796) |
| 0.0 | 0.3 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 0.2 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 0.1 | 0.2 | GO:0000802 | transverse filament(GO:0000802) |
| 0.0 | 0.2 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681) |
| 0.0 | 0.2 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.0 | 0.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.1 | 0.5 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) NFAT protein binding(GO:0051525) |
| 0.1 | 0.4 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.1 | 0.4 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.0 | 0.4 | GO:0015288 | porin activity(GO:0015288) |
| 0.0 | 0.3 | GO:0015556 | C4-dicarboxylate transmembrane transporter activity(GO:0015556) |
| 0.0 | 0.3 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.0 | 0.3 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.0 | 0.2 | GO:0050785 | IgE binding(GO:0019863) advanced glycation end-product receptor activity(GO:0050785) |
| 0.0 | 0.2 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 0.3 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.0 | 0.2 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.1 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.5 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.2 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 0.2 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 0.2 | REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
| 0.0 | 0.1 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.0 | 0.1 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |