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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Zbtb3
Z-value: 0.58
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Transcription factors associated with Zbtb3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zbtb3 | rn6_v1_chr1_+_224998172_224998172 | 0.85 | 6.9e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_71210301 Show fit | 0.39 |
ENSRNOT00000006504
|
family with sequence similarity 171, member B |
|
| chr16_-_84939323 Show fit | 0.35 |
ENSRNOT00000022742
|
myosin XVI |
|
| chr1_+_226435979 Show fit | 0.34 |
ENSRNOT00000048704
ENSRNOT00000036232 ENSRNOT00000035576 ENSRNOT00000036180 ENSRNOT00000036168 ENSRNOT00000047964 ENSRNOT00000036283 ENSRNOT00000007429 |
synaptotagmin 7 |
|
| chr1_-_261446570 Show fit | 0.23 |
ENSRNOT00000020182
|
secreted frizzled-related protein 5 |
|
| chr7_-_113937941 Show fit | 0.20 |
ENSRNOT00000012408
|
potassium two pore domain channel subfamily K member 9 |
|
| chr3_+_161433410 Show fit | 0.20 |
ENSRNOT00000024657
|
solute carrier family 12 member 5 |
|
| chrX_+_65040934 Show fit | 0.20 |
ENSRNOT00000044006
|
zinc finger CCCH-type containing 12B |
|
| chr1_-_65597899 Show fit | 0.19 |
ENSRNOT00000046708
|
zinc finger protein 446 |
|
| chr11_+_69739384 Show fit | 0.19 |
ENSRNOT00000016340
|
kalirin, RhoGEF kinase |
|
| chr14_+_86652365 Show fit | 0.18 |
ENSRNOT00000077428
|
zinc finger, MIZ-type containing 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Zbtb3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:1990926 | short-term synaptic potentiation(GO:1990926) |
| 0.1 | 0.2 | GO:2000040 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
| 0.0 | 0.2 | GO:0061366 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) NMDA selective glutamate receptor signaling pathway(GO:0098989) |
| 0.0 | 0.2 | GO:0038170 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 0.0 | 0.2 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.0 | 0.2 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.0 | 0.1 | GO:1902214 | regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of apoptotic cell clearance(GO:2000426) |
| 0.0 | 0.1 | GO:0001982 | baroreceptor response to decreased systemic arterial blood pressure(GO:0001982) |
| 0.0 | 0.1 | GO:0003051 | angiotensin-mediated drinking behavior(GO:0003051) |
| 0.0 | 0.1 | GO:0072156 | distal tubule morphogenesis(GO:0072156) metanephric proximal tubule development(GO:0072237) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0032009 | early phagosome(GO:0032009) |
| 0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.0 | 0.1 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.0 | 0.1 | GO:0008275 | gamma-tubulin small complex(GO:0008275) |
| 0.0 | 0.1 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.0 | 0.1 | GO:0097441 | basilar dendrite(GO:0097441) |
| 0.0 | 0.1 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.0 | 0.0 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 0.0 | 0.0 | GO:1990836 | lysosomal matrix(GO:1990836) |
| 0.0 | 0.0 | GO:0005899 | insulin receptor complex(GO:0005899) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.0 | 0.2 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.1 | GO:0004478 | methionine adenosyltransferase activity(GO:0004478) |
| 0.0 | 0.1 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 0.0 | 0.1 | GO:0000991 | transcription factor activity, core RNA polymerase II binding(GO:0000991) |
| 0.0 | 0.1 | GO:0047635 | L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635) |
| 0.0 | 0.1 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.0 | 0.1 | GO:0016972 | thiol oxidase activity(GO:0016972) |
| 0.0 | 0.1 | GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.0 | 0.1 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |