ISMARA results: Xbp1

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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Xbp1_Creb3l1

Z-value: 0.38

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Transcription factors associated with Xbp1_Creb3l1

Gene Symbol	Gene ID	Gene Info
Xbp1 NCBI RGD Ensembl	ENSRNOG00000010298	X-box binding protein 1
Creb3l1 NCBI RGD Ensembl	ENSRNOG00000005413	cAMP responsive element binding protein 3-like 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Creb3l1	rn6_v1_chr3_-_80933283_80933283	0.74	1.5e-01	Click!
Xbp1	rn6_v1_chr14_+_85753760_85753760	-0.19	7.5e-01	Click!

Activity profile of Xbp1_Creb3l1 motif

Sorted Z-values of Xbp1_Creb3l1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_-_41671437 Show fit	0.28	ENSRNOT00000001883	Lhx5 NCBI RGD Ensembl Show fit	LIM homeobox 5
chr17_+_6909728 Show fit	0.21	ENSRNOT00000061231	LOC681410 NCBI RGD Ensembl Show fit	hypothetical protein LOC681410
chr8_-_98738446 Show fit	0.20	ENSRNOT00000019860	Zic1 NCBI RGD Ensembl Show fit	Zic family member 1
chr1_-_190965115 Show fit	0.14	ENSRNOT00000023483	AC103221.1 NCBI RGD Ensembl Show fit
chr1_+_105284753 Show fit	0.12	ENSRNOT00000041950	Slc6a5 NCBI RGD Ensembl Show fit	solute carrier family 6 member 5
chr14_+_11198896 Show fit	0.12	ENSRNOT00000079767	Hnrnpdl NCBI RGD Ensembl Show fit	heterogeneous nuclear ribonucleoprotein D-like
chr18_+_73157973 Show fit	0.10	ENSRNOT00000031993	Skor2 NCBI RGD Ensembl Show fit	SKI family transcriptional corepressor 2
chr14_+_83752393 Show fit	0.10	ENSRNOT00000081123	Selenom NCBI RGD Ensembl Show fit	selenoprotein M
chr3_+_14889510 Show fit	0.09	ENSRNOT00000080760	Dab2ip NCBI RGD Ensembl Show fit	DAB2 interacting protein
chr1_+_199941161 Show fit	0.09	ENSRNOT00000027616	Bag3 NCBI RGD Ensembl Show fit	Bcl2-associated athanogene 3

Showing 1 to 10 of 135 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Xbp1_Creb3l1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Total log-likelihood	Term	Description
0.3	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.2	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.1	GO:0036233	glycine import(GO:0036233)
0.1	GO:0036324	vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1	GO:1990523	bone regeneration(GO:1990523)
0.1	GO:0060764	cell-cell signaling involved in mammary gland development(GO:0060764)
0.1	GO:0021936	regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.1	GO:1901073	glucosamine-containing compound biosynthetic process(GO:1901073)
0.1	GO:0035934	corticosterone secretion(GO:0035934)

Showing 1 to 10 of 12 entries

Gene overrepresentation in cellular component category:

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Total log-likelihood	Term	Description
0.1	GO:1990032	parallel fiber(GO:1990032)
0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0	GO:0045242	mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)

Showing 1 to 6 of 6 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.2	GO:0034046	poly(G) binding(GO:0034046)
0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)

Showing 1 to 7 of 7 entries

Results for Xbp1_Creb3l1

Z-value: 0.38

Motif logo

Transcription factors associated with Xbp1_Creb3l1

Activity-expression correlation:

Activity profile of Xbp1_Creb3l1 motif

Sorted Z-values of Xbp1_Creb3l1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Xbp1_Creb3l1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: