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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Vsx1_Uncx_Prrx2_Shox2_Noto

Z-value: 0.98

Motif logo

Transcription factors associated with Vsx1_Uncx_Prrx2_Shox2_Noto

Gene Symbol Gene ID Gene Info
ENSRNOG00000042220 visual system homeobox 1
ENSRNOG00000001284 UNC homeobox
ENSRNOG00000058329 paired related homeobox 2
ENSRNOG00000012478 short stature homeobox 2
ENSRNOG00000037863 notochord homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Uncxrn6_v1_chr12_-_17186679_171866790.761.4e-01Click!
Shox2rn6_v1_chr2_-_164126783_1641267830.652.3e-01Click!
Prrx2rn6_v1_chr3_+_9681871_96818710.286.5e-01Click!
Vsx1rn6_v1_chr3_-_146491837_146491837-0.089.0e-01Click!

Activity profile of Vsx1_Uncx_Prrx2_Shox2_Noto motif

Sorted Z-values of Vsx1_Uncx_Prrx2_Shox2_Noto motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_2174131 6.90 ENSRNOT00000001313
Purkinje cell protein 2
chr10_-_88670430 2.25 ENSRNOT00000025547
hypocretin neuropeptide precursor
chr2_+_145174876 1.66 ENSRNOT00000040631
mab-21 like 1
chr12_-_17186679 1.35 ENSRNOT00000001730
UNC homeobox
chr4_-_80395502 1.10 ENSRNOT00000014437
neuropeptide VF precursor
chr2_-_185852759 0.71 ENSRNOT00000049461
mab-21 like 2
chr17_+_11683862 0.68 ENSRNOT00000024766
msh homeobox 2
chr1_+_105284753 0.60 ENSRNOT00000041950
solute carrier family 6 member 5
chr10_-_87232723 0.49 ENSRNOT00000015150
keratin 25
chr6_-_125723732 0.49 ENSRNOT00000084815
fibulin 5
chr3_+_95715193 0.44 ENSRNOT00000089525
paired box 6
chr4_-_180234804 0.40 ENSRNOT00000070957
basic helix-loop-helix family, member e41
chr3_-_7498555 0.38 ENSRNOT00000017725
BarH-like homeobox 1
chr5_+_50381244 0.33 ENSRNOT00000012385
glycoprotein hormones, alpha polypeptide
chr6_-_125723944 0.32 ENSRNOT00000007004
fibulin 5
chr8_+_71914867 0.31 ENSRNOT00000023372
death-associated protein kinase 2
chr14_+_4362717 0.29 ENSRNOT00000002887
BarH-like homeobox 2
chr1_-_173764246 0.29 ENSRNOT00000019690
ENSRNOT00000086944
LIM domain only 1
chr2_+_196334626 0.27 ENSRNOT00000050914
ENSRNOT00000028645
ENSRNOT00000090729
semaphorin 6C
chr6_+_28382962 0.27 ENSRNOT00000016976
proopiomelanocortin
chr10_-_87286387 0.25 ENSRNOT00000044206
keratin 28
chr10_+_103395511 0.23 ENSRNOT00000004256
G protein-coupled receptor, class C, group 5, member C
chr3_+_14889510 0.23 ENSRNOT00000080760
DAB2 interacting protein
chr3_+_5709236 0.22 ENSRNOT00000061201
ENSRNOT00000070887
dopamine beta-hydroxylase
chr6_-_106971250 0.22 ENSRNOT00000010926
double PHD fingers 3
chr12_-_45801842 0.21 ENSRNOT00000078837

chr13_+_49005405 0.18 ENSRNOT00000092560
ENSRNOT00000076457
LEM domain containing 1
chr7_-_28711761 0.17 ENSRNOT00000006249
PARP1 binding protein
chr7_+_136182224 0.17 ENSRNOT00000008159
transmembrane protein 117
chr1_-_124803363 0.16 ENSRNOT00000066380
Kruppel-like factor 13
chr3_+_45683993 0.15 ENSRNOT00000038983
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr20_+_44680449 0.15 ENSRNOT00000000728
Traf3 interacting protein 2
chr3_-_57607683 0.15 ENSRNOT00000093222
ENSRNOT00000058524
methyltransferase like 8
chr2_+_239415046 0.13 ENSRNOT00000072196
CXXC finger protein 4
chr1_-_48825364 0.13 ENSRNOT00000024213
1-acylglycerol-3-phosphate O-acyltransferase 4
chr15_-_95514259 0.13 ENSRNOT00000038433
SLIT and NTRK-like family, member 6
chr4_+_22898527 0.13 ENSRNOT00000072455
ENSRNOT00000076123
DBF4 zinc finger
chr5_-_12526962 0.13 ENSRNOT00000092104
suppression of tumorigenicity 18
chr14_+_42714315 0.13 ENSRNOT00000084095
ENSRNOT00000091449
paired-like homeobox 2b
chr2_-_45518502 0.12 ENSRNOT00000014627
heat shock protein family B (small) member 3
chr3_-_141411170 0.12 ENSRNOT00000017364
NK2 homeobox 2
chr17_-_14627937 0.12 ENSRNOT00000020532
osteoglycin
chr16_+_54358471 0.12 ENSRNOT00000047314
microtubule associated tumor suppressor 1
chrX_-_124464963 0.11 ENSRNOT00000036472
ENSRNOT00000077697
transmembrane protein 255A
chr1_+_101178104 0.11 ENSRNOT00000028072
parathyroid hormone 2
chr4_-_100252755 0.11 ENSRNOT00000017301
vesicle-associated membrane protein 8
chr9_-_85243001 0.10 ENSRNOT00000020219
secretogranin II
chr6_-_7058314 0.10 ENSRNOT00000045996
3-hydroxyanthranilate 3,4-dioxygenase
chr6_-_67084234 0.10 ENSRNOT00000050372
NOVA alternative splicing regulator 1
chr7_+_72924799 0.09 ENSRNOT00000008969
lysosomal protein transmembrane 4 beta
chr6_+_58468155 0.09 ENSRNOT00000091263
ets variant 1
chr13_+_71107465 0.08 ENSRNOT00000003239
regulator of G-protein signaling 8
chrX_-_118998300 0.08 ENSRNOT00000025575

chr10_+_91217079 0.08 ENSRNOT00000004218
hexamethylene bis-acetamide inducible 2
chr2_+_80269661 0.08 ENSRNOT00000015975

chr4_+_158088505 0.08 ENSRNOT00000026643
von Willebrand factor
chr1_+_101599018 0.08 ENSRNOT00000028494
fucosyltransferase 1
chr7_-_107616038 0.08 ENSRNOT00000088752
src-like adaptor
chr6_-_111417813 0.07 ENSRNOT00000016324
ENSRNOT00000085458
serine palmitoyltransferase, long chain base subunit 2
chr3_-_161917285 0.07 ENSRNOT00000025150
cadherin 22
chrX_+_118197217 0.07 ENSRNOT00000090922
5-hydroxytryptamine receptor 2C
chr3_-_11452529 0.07 ENSRNOT00000020206
solute carrier family 25 member 25
chr2_-_123972356 0.07 ENSRNOT00000023348
interleukin 21
chrX_+_6273733 0.07 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr4_+_180062799 0.07 ENSRNOT00000021623
Ras association domain family member 8
chr13_-_32427177 0.07 ENSRNOT00000044628
cadherin 19
chr2_+_158097843 0.07 ENSRNOT00000016541
pentraxin 3
chr2_+_51672722 0.06 ENSRNOT00000016485
fibroblast growth factor 10
chr7_+_3173287 0.06 ENSRNOT00000092037
PYM homolog 1, exon junction complex associated factor
chr10_-_84920886 0.06 ENSRNOT00000068083
Sp2 transcription factor
chr1_-_215033460 0.06 ENSRNOT00000044565
dual specificity phosphatase 8
chr9_-_18371856 0.06 ENSRNOT00000027293
SPT3 homolog, SAGA and STAGA complex component
chr5_-_150704117 0.06 ENSRNOT00000067455
sestrin 2
chr9_-_82146874 0.06 ENSRNOT00000024190
FEV, ETS transcription factor
chr1_-_90149991 0.06 ENSRNOT00000076987
similar to RIKEN cDNA 4931406P16
chr4_-_17594598 0.06 ENSRNOT00000008936
semaphorin 3E
chr4_-_18396035 0.06 ENSRNOT00000034692
semaphorin 3A
chr9_+_10941613 0.06 ENSRNOT00000070794
semaphorin 6B
chr19_+_53044379 0.06 ENSRNOT00000072369
forkhead box C2
chr2_+_210880777 0.06 ENSRNOT00000026237
G protein subunit alpha transducin 2
chr4_+_68656928 0.06 ENSRNOT00000016232
taste receptor, type 2, member 108
chr2_-_32518643 0.06 ENSRNOT00000061032
microtubule associated serine/threonine kinase family member 4
chr2_+_198755262 0.06 ENSRNOT00000028807
RNA binding motif protein 8A
chr16_+_7035241 0.06 ENSRNOT00000084977
NIMA-related kinase 4
chr9_+_73418607 0.05 ENSRNOT00000092547
microtubule-associated protein 2
chr15_-_37830131 0.05 ENSRNOT00000075861
eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1
chr10_+_17579284 0.05 ENSRNOT00000079698
F-box and WD repeat domain containing 11
chr3_-_44086006 0.05 ENSRNOT00000034449
ENSRNOT00000082604
ermin
chr15_+_108318664 0.05 ENSRNOT00000057469
UBA domain containing 2
chr2_-_58534211 0.05 ENSRNOT00000089178
S-phase kinase associated protein 2
chr18_-_49937522 0.05 ENSRNOT00000033254
zinc finger protein 608
chr16_+_63958645 0.05 ENSRNOT00000081522
ENSRNOT00000082355
ENSRNOT00000013991
neuregulin 1
chr8_+_47674321 0.05 ENSRNOT00000026170
ENSRNOT00000078776
tripartite motif-containing 29
chr14_-_16903242 0.05 ENSRNOT00000003001
shroom family member 3
chr9_+_81566074 0.05 ENSRNOT00000074131
ENSRNOT00000046229
ENSRNOT00000090383
paroxysmal nonkinesigenic dyskinesia
chrX_+_33443186 0.04 ENSRNOT00000005622
S100 calcium binding protein G
chr18_-_26656879 0.04 ENSRNOT00000086729
erythrocyte membrane protein band 4.1 like 4A
chrX_-_104932508 0.04 ENSRNOT00000075325
NADPH oxidase 1
chrX_+_156463953 0.04 ENSRNOT00000079889
filamin A
chr5_-_136965191 0.04 ENSRNOT00000056842
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
chr10_-_88172910 0.04 ENSRNOT00000046956
keratin 42
chr1_+_13595295 0.04 ENSRNOT00000079250
NHS-like 1
chr1_-_15374850 0.04 ENSRNOT00000016728
peroxisomal biogenesis factor 7
chr1_+_185210922 0.04 ENSRNOT00000055120
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr7_-_101138373 0.04 ENSRNOT00000043257
Ab1-152
chr1_-_134871167 0.04 ENSRNOT00000076300
chromodomain helicase DNA binding protein 2
chrX_-_80142902 0.04 ENSRNOT00000071650
high mobility group nucleosome binding domain 5
chr15_+_11298478 0.04 ENSRNOT00000007672
leucine rich repeat containing 3B
chr15_+_44441856 0.04 ENSRNOT00000018006
gonadotropin releasing hormone 1
chr14_+_76732650 0.04 ENSRNOT00000088197
cytokine-dependent hematopoietic cell linker
chr5_+_139790395 0.03 ENSRNOT00000015033
regulating synaptic membrane exocytosis 3
chr9_-_53315915 0.03 ENSRNOT00000038093
myostatin
chr2_+_226563050 0.03 ENSRNOT00000065111
breast cancer anti-estrogen resistance 3
chr2_+_154580558 0.03 ENSRNOT00000076976
guanine monophosphate synthase
chr8_-_53816447 0.03 ENSRNOT00000011454
tetratricopeptide repeat domain 12
chr5_-_28131133 0.03 ENSRNOT00000067331
solute carrier family 26 member 7
chr13_-_99101208 0.03 ENSRNOT00000004329
H3 histone family member 3A
chr18_+_867048 0.03 ENSRNOT00000065494
collectin sub-family member 12
chr5_+_129756149 0.03 ENSRNOT00000067277
DMRT-like family A2
chr9_+_88493593 0.03 ENSRNOT00000020712
mitochondrial fission factor-like
chr19_+_39229754 0.03 ENSRNOT00000050612
vacuolar protein sorting 4 homolog A
chrX_+_159158194 0.03 ENSRNOT00000043820
ENSRNOT00000001169
ENSRNOT00000083502
four and a half LIM domains 1
chr19_-_49448072 0.03 ENSRNOT00000014997
C-x(9)-C motif containing 2
chr18_+_51523758 0.03 ENSRNOT00000078518
GRAM domain containing 3
chr2_-_235249571 0.03 ENSRNOT00000093631
ENSRNOT00000085096
retinal pigment epithelium derived rhodopsin homolog
chr2_+_225645568 0.03 ENSRNOT00000017878
ATP binding cassette subfamily A member 4
chr4_-_56786754 0.03 ENSRNOT00000050795
kielin/chordin-like protein
chr18_-_61057365 0.03 ENSRNOT00000042352
alpha-kinase 2
chr4_-_4473307 0.03 ENSRNOT00000045773
dipeptidyl peptidase like 6
chr5_+_58855773 0.03 ENSRNOT00000072869
RUN and SH3 domain containing 2
chr10_-_93675991 0.03 ENSRNOT00000090662
membrane associated ring-CH-type finger 10
chr11_-_4397361 0.03 ENSRNOT00000046370
cell adhesion molecule 2
chr18_-_12640716 0.03 ENSRNOT00000020697
kelch-like family member 14
chr4_-_157304653 0.03 ENSRNOT00000051613
leucine rich repeat containing 23
chr1_+_264741911 0.03 ENSRNOT00000019956
semaphorin 4G
chr7_-_142062870 0.02 ENSRNOT00000026531
solute carrier family 11 member 2
chr1_+_193076430 0.02 ENSRNOT00000086492
ENSRNOT00000017885
trinucleotide repeat containing 6a
chr3_+_113319456 0.02 ENSRNOT00000051354
creatine kinase, mitochondrial 1
chr11_-_32550539 0.02 ENSRNOT00000002715
regulator of calcineurin 1
chr20_-_3728844 0.02 ENSRNOT00000074958
psoriasis susceptibility 1 candidate 2
chr17_-_77527894 0.02 ENSRNOT00000032173
BEN domain containing 7
chr15_+_31950986 0.02 ENSRNOT00000080233

chr2_-_88553086 0.02 ENSRNOT00000042494
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr2_+_102685513 0.02 ENSRNOT00000033940
basic helix-loop-helix family, member e22
chr3_-_102826379 0.02 ENSRNOT00000073423
olfactory receptor 769
chr13_+_87986240 0.02 ENSRNOT00000003705
regulator of G-protein signaling 5
chr8_+_103938520 0.02 ENSRNOT00000067835
glycerol kinase 5 (putative)
chr16_-_74264142 0.02 ENSRNOT00000026067
dickkopf WNT signaling pathway inhibitor 4
chr20_+_45458558 0.02 ENSRNOT00000000713
cyclin-dependent kinase 19
chr3_-_37803112 0.02 ENSRNOT00000059461
nebulin
chr6_+_146784915 0.02 ENSRNOT00000008362
Sp8 transcription factor
chr12_-_35979193 0.02 ENSRNOT00000071104
transmembrane protein 132B
chr4_-_21920651 0.02 ENSRNOT00000066211
transmembrane protein 243
chr7_+_44009069 0.02 ENSRNOT00000005523
MGAT4 family, member C
chr14_-_44078897 0.02 ENSRNOT00000031792
NEDD4 binding protein 2
chr11_+_13499164 0.02 ENSRNOT00000013159
similar to heat shock protein 8
chr16_+_4469468 0.02 ENSRNOT00000021164
wingless-type MMTV integration site family, member 5A
chr1_+_277355619 0.02 ENSRNOT00000022788
NHL repeat containing 2
chr1_+_127802978 0.02 ENSRNOT00000055877
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr10_-_91986632 0.02 ENSRNOT00000087824
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr7_+_42269784 0.02 ENSRNOT00000008471
ENSRNOT00000007231
KIT ligand
chr9_-_81566096 0.02 ENSRNOT00000019497
angio-associated, migratory cell protein
chr1_-_102699442 0.02 ENSRNOT00000056109
tryptophan hydroxylase 1
chr9_+_20241062 0.01 ENSRNOT00000071593
leucine-rich repeat-containing protein 23-like
chr6_+_2216623 0.01 ENSRNOT00000008045
regulator of microtubule dynamics 2
chr6_-_115616766 0.01 ENSRNOT00000006143
ENSRNOT00000045870
SEL1L ERAD E3 ligase adaptor subunit
chr11_-_76888178 0.01 ENSRNOT00000049841
osteocrin
chr3_+_2591331 0.01 ENSRNOT00000017466
suppressor APC domain containing 2
chr3_+_95233874 0.01 ENSRNOT00000079743
hypothetical protein LOC691083
chr10_-_87195075 0.01 ENSRNOT00000014851
keratin 24
chr9_+_79630604 0.01 ENSRNOT00000021539
ENSRNOT00000083979
transmembrane protein 169
chr18_-_32670665 0.01 ENSRNOT00000019409
nuclear receptor subfamily 3, group C, member 1
chr1_-_134867001 0.01 ENSRNOT00000090149
chromodomain helicase DNA binding protein 2
chr16_+_50049828 0.01 ENSRNOT00000034448
family with sequence similarity 149, member A
chr7_+_2752680 0.01 ENSRNOT00000033726
citrate synthase
chr9_-_79630452 0.01 ENSRNOT00000078125
ENSRNOT00000086044
ENSRNOT00000089283
peroxisomal trans-2-enoyl-CoA reductase
chr6_+_125876109 0.01 ENSRNOT00000091300
cleavage and polyadenylation specific factor 2
chr12_+_39423596 0.01 ENSRNOT00000066952
intraflagellar transport 81
chr3_-_45169118 0.01 ENSRNOT00000086371
coiled-coil domain containing 148
chr6_-_23316962 0.01 ENSRNOT00000065421
CAP-GLY domain containing linker protein family, member 4
chr11_+_45751812 0.01 ENSRNOT00000079336
similar to Dermal papilla derived protein 7
chr3_+_10036461 0.01 ENSRNOT00000073731
pyroglutamylated RFamide peptide
chr7_-_15073052 0.01 ENSRNOT00000037708
zinc finger protein 799
chr3_+_110855000 0.01 ENSRNOT00000081613
kinetochore scaffold 1
chr5_-_28130803 0.01 ENSRNOT00000093186
solute carrier family 26 member 7
chr10_+_54352270 0.01 ENSRNOT00000036752
dehydrogenase/reductase 7C
chr10_+_53740841 0.01 ENSRNOT00000004295
myosin heavy chain 2
chr3_+_138508899 0.01 ENSRNOT00000009437
lysine acetyltransferase 14
chr11_+_80742467 0.01 ENSRNOT00000002507
mannan-binding lectin serine peptidase 1
chr8_+_23193181 0.01 ENSRNOT00000071703
zinc finger protein 872
chr3_+_9403840 0.01 ENSRNOT00000071380
pyroglutamylated RFamide peptide
chr4_+_61924013 0.01 ENSRNOT00000090717
bisphosphoglycerate mutase
chr15_+_4064706 0.01 ENSRNOT00000011956
synaptopodin 2-like
chr7_+_42304534 0.00 ENSRNOT00000085097
KIT ligand
chr19_+_38039729 0.00 ENSRNOT00000089783
nuclear factor of activated T-cells 3
chr2_+_118910587 0.00 ENSRNOT00000065518
zinc finger protein 639
chr2_-_248484100 0.00 ENSRNOT00000040856
guanylate binding protein 3
chr4_-_169036950 0.00 ENSRNOT00000011295
germ cell associated 1
chr2_+_41442241 0.00 ENSRNOT00000067546
phosphodiesterase 4D
chr7_-_49741540 0.00 ENSRNOT00000006523
myogenic factor 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Vsx1_Uncx_Prrx2_Shox2_Noto

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.6 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.3 2.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 0.7 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 1.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.4 GO:0021918 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.1 0.6 GO:0036233 glycine import(GO:0036233)
0.1 0.3 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.1 1.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.1 GO:0021550 medulla oblongata development(GO:0021550) sensory system development(GO:0048880)
0.0 0.2 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.3 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.0 0.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:1902276 pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276) positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0 0.1 GO:1903015 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.0 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:0060661 mammary gland bud morphogenesis(GO:0060648) submandibular salivary gland formation(GO:0060661) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0021824 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) facioacoustic ganglion development(GO:1903375)
0.0 0.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) positive regulation of vascular wound healing(GO:0035470) glomerular endothelium development(GO:0072011) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.0 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:1901367 response to L-cysteine(GO:1901367)
0.0 0.1 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0071953 elastic fiber(GO:0071953)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.1 0.2 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0071565 nBAF complex(GO:0071565)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 2.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.3 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.4 GO:0043426 MRF binding(GO:0043426)
0.1 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 6.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.0 GO:0003922 GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
0.0 0.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 2.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression