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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Trp53
Z-value: 0.52
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Transcription factors associated with Trp53
| Gene Symbol | Gene ID | Gene Info |
|---|
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tp53 | rn6_v1_chr10_+_56193856_56193866 | -0.94 | 1.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_63176463 Show fit | 0.35 |
ENSRNOT00000004717
|
solute carrier family 6 member 4 |
|
| chr7_-_28711761 Show fit | 0.26 |
ENSRNOT00000006249
|
PARP1 binding protein |
|
| chr8_+_72743426 Show fit | 0.24 |
ENSRNOT00000072573
|
ribosomal protein S27-like |
|
| chr6_-_76270457 Show fit | 0.24 |
ENSRNOT00000009894
|
NFKB inhibitor alpha |
|
| chr14_-_37770059 Show fit | 0.22 |
ENSRNOT00000029721
|
solute carrier family 10, member 4 |
|
| chr5_-_153924896 Show fit | 0.21 |
ENSRNOT00000065247
|
grainyhead-like transcription factor 3 |
|
| chr20_-_14020007 Show fit | 0.20 |
ENSRNOT00000093521
|
gamma-glutamyltransferase 1 |
|
| chr19_+_41482728 Show fit | 0.18 |
ENSRNOT00000022943
|
calbindin 2 |
|
| chr10_-_90049112 Show fit | 0.18 |
ENSRNOT00000028323
|
peptide YY (mapped) |
|
| chr20_-_3439983 Show fit | 0.17 |
ENSRNOT00000080822
ENSRNOT00000001099 |
immediate early response 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Trp53
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.1 | 0.4 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
| 0.0 | 0.2 | GO:0031179 | peptide modification(GO:0031179) |
| 0.0 | 0.2 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
| 0.0 | 0.2 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.0 | 0.2 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.0 | 0.2 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
| 0.0 | 0.2 | GO:0045820 | negative regulation of glycolytic process(GO:0045820) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.0 | 0.2 | GO:0032096 | negative regulation of response to food(GO:0032096) |
| 0.0 | 0.1 | GO:0045799 | positive regulation of chromatin assembly or disassembly(GO:0045799) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.1 | GO:0097453 | mesaxon(GO:0097453) ensheathing process(GO:1990015) |
| 0.0 | 0.1 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.0 | 0.1 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 0.0 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0015222 | serotonin transmembrane transporter activity(GO:0015222) |
| 0.1 | 0.2 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.0 | 0.2 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.2 | GO:0036374 | gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374) |
| 0.0 | 0.2 | GO:0019841 | retinol binding(GO:0019841) |
| 0.0 | 0.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
| 0.0 | 0.1 | GO:0004478 | methionine adenosyltransferase activity(GO:0004478) |
| 0.0 | 0.1 | GO:0004365 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.0 | 0.1 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.0 | 0.1 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.0 | 0.2 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.0 | 0.1 | REACTOME OPSINS | Genes involved in Opsins |