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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Thrb

Z-value: 0.32

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Transcription factors associated with Thrb

Gene Symbol Gene ID Gene Info
ENSRNOG00000006649 thyroid hormone receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Thrbrn6_v1_chr15_-_8914501_89145010.592.9e-01Click!

Activity profile of Thrb motif

Sorted Z-values of Thrb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_88135410 0.40 ENSRNOT00000014180
carbonic anhydrase 3
chr4_-_30276372 0.09 ENSRNOT00000011823
paraoxonase 1
chr10_-_52483325 0.08 ENSRNOT00000083485

chr1_+_88875375 0.08 ENSRNOT00000028284
Tyro protein tyrosine kinase binding protein
chr8_-_84506328 0.08 ENSRNOT00000064754
muscular LMNA-interacting protein
chr17_+_45175121 0.07 ENSRNOT00000080417
NFKB activating protein-like
chr3_+_81294275 0.07 ENSRNOT00000009068
similar to RIKEN cDNA 1700029I15
chr3_+_148438939 0.07 ENSRNOT00000064196
tubulin tyrosine ligase like 9
chr10_+_108387789 0.07 ENSRNOT00000084845

chr3_-_6626284 0.06 ENSRNOT00000012494
ficolin B
chr14_+_43694183 0.05 ENSRNOT00000046342
similar to ribosomal protein S23
chr4_+_102147211 0.05 ENSRNOT00000083239

chr4_-_157252104 0.05 ENSRNOT00000082739
protein tyrosine phosphatase, non-receptor type 6
chr3_-_4055806 0.05 ENSRNOT00000026408
1-acylglycerol-3-phosphate O-acyltransferase 2
chr9_+_17728816 0.05 ENSRNOT00000065754
calpain 11
chr10_-_56962161 0.05 ENSRNOT00000026038
arachidonate 15-lipoxygenase
chr2_-_209973205 0.04 ENSRNOT00000024593
chymosin
chr15_-_45376324 0.04 ENSRNOT00000076969
deleted in lymphocytic leukemia, 7
chr5_+_34040258 0.04 ENSRNOT00000009758
gamma-glutamyl hydrolase
chr13_+_50977431 0.04 ENSRNOT00000035658
chitinase 1
chr13_-_91776397 0.04 ENSRNOT00000073147
mucosal pentraxin 1
chr7_+_118712035 0.03 ENSRNOT00000074245
apolipoprotein L3-like
chr8_+_111107358 0.03 ENSRNOT00000011203
anaphase promoting complex subunit 13
chr8_-_115358046 0.03 ENSRNOT00000017607
glutamate metabotropic receptor 2
chr14_-_81053905 0.03 ENSRNOT00000045068
ENSRNOT00000040215
regulator of G-protein signaling 12
chr3_-_26056818 0.03 ENSRNOT00000044209
LDL receptor related protein 1B
chr5_-_113939127 0.03 ENSRNOT00000039554
myb-like, SWIRM and MPN domains 1
chr1_-_170431073 0.03 ENSRNOT00000024710
hemopexin
chr8_+_115131367 0.02 ENSRNOT00000014849
ribosomal protein L29
chr1_-_78626284 0.02 ENSRNOT00000052299
carcinoembryonic antigen-related cell adhesion molecule 3-like
chr12_+_50315933 0.02 ENSRNOT00000000826
SRR1 domain containing
chr4_-_157252565 0.02 ENSRNOT00000079947
protein tyrosine phosphatase, non-receptor type 6
chr16_+_4997461 0.02 ENSRNOT00000071042
leucine-rich repeat and transmembrane domain-containing protein 1-like
chr7_-_98197087 0.02 ENSRNOT00000010484
ENSRNOT00000079961
kelch-like family member 38
chr13_+_93751759 0.02 ENSRNOT00000065706
WD repeat domain 64
chr3_-_160922341 0.02 ENSRNOT00000029206
TP53 target 5
chr4_+_52147641 0.02 ENSRNOT00000009458
hyaluronoglucosaminidase 4
chr1_-_216920625 0.02 ENSRNOT00000028119
oxysterol binding protein-like 5
chr5_+_133865331 0.02 ENSRNOT00000035409
TAL bHLH transcription factor 1, erythroid differentiation factor
chr15_+_57290849 0.02 ENSRNOT00000014909
carboxypeptidase B2
chr1_-_222902320 0.01 ENSRNOT00000059154
galectin 12
chr5_+_163867961 0.01 ENSRNOT00000081495

chr10_-_76263866 0.01 ENSRNOT00000003219
serine carboxypeptidase 1
chr3_+_7051695 0.01 ENSRNOT00000013548
mitochondrial ribosomal protein S2
chr10_+_31508512 0.01 ENSRNOT00000031580
family with sequence similarity 71, member B
chr16_+_74865516 0.01 ENSRNOT00000058072
ATPase copper transporting beta
chrX_-_153039372 0.01 ENSRNOT00000085250
paraneoplastic Ma antigen family member 5
chr10_-_88619537 0.01 ENSRNOT00000055250
lysine acetyltransferase 2A
chr1_+_192933540 0.01 ENSRNOT00000035770
RB binding protein 6, ubiquitin ligase
chr19_-_57422093 0.01 ENSRNOT00000025512
similar to RIKEN cDNA 2310022B05
chr10_-_45279299 0.01 ENSRNOT00000073082
ring finger protein 187
chr7_+_97778260 0.01 ENSRNOT00000064264
TBC1 domain family, member 31
chr7_+_35125424 0.01 ENSRNOT00000085978
ENSRNOT00000010117
NADH:ubiquinone oxidoreductase subunit A12
chr15_-_48284548 0.00 ENSRNOT00000038336
homeobox containing 1
chr17_-_90522091 0.00 ENSRNOT00000077767
lysosomal trafficking regulator
chr1_+_219144205 0.00 ENSRNOT00000083942
unc-93 homolog B1 (C. elegans)
chr3_+_138765027 0.00 ENSRNOT00000055588
RGD1566320
chr10_-_110431792 0.00 ENSRNOT00000054922
hypothetical protein LOC619574
chr4_-_162498052 0.00 ENSRNOT00000066349
chromobox homolog 3-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Thrb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:2001204 regulation of osteoclast development(GO:2001204)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.0 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)