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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Tfap4
Z-value: 0.64
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Transcription factors associated with Tfap4
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tfap4 | rn6_v1_chr10_+_11206226_11206226 | 0.41 | 4.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_157538303 Show fit | 0.59 |
ENSRNOT00000086418
|
zinc finger protein 384 |
|
| chr10_+_85301875 Show fit | 0.41 |
ENSRNOT00000080935
|
suppressor of cytokine signaling 7 |
|
| chr17_+_12762752 Show fit | 0.36 |
ENSRNOT00000044842
|
DIRAS family GTPase 2 |
|
| chr5_+_90800082 Show fit | 0.36 |
ENSRNOT00000093696
ENSRNOT00000093206 |
lysine demethylase 4C |
|
| chr2_-_140618405 Show fit | 0.34 |
ENSRNOT00000017736
|
SET domain containing (lysine methyltransferase) 7 |
|
| chr9_-_66033871 Show fit | 0.30 |
ENSRNOT00000035209
|
ALS2, alsin Rho guanine nucleotide exchange factor |
|
| chr1_-_219745654 Show fit | 0.23 |
ENSRNOT00000054848
|
hypothetical protein LOC689065 |
|
| chr9_+_94425252 Show fit | 0.22 |
ENSRNOT00000064965
ENSRNOT00000076099 |
GRB10 interacting GYF protein 2 |
|
| chr10_-_64642292 Show fit | 0.22 |
ENSRNOT00000084670
|
active BCR-related |
|
| chrX_+_62754634 Show fit | 0.21 |
ENSRNOT00000016669
|
phosphate cytidylyltransferase 1, choline, beta |
Network of associatons between targets according to the STRING database.
First level regulatory network of Tfap4
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.0 | 0.4 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.0 | 0.3 | GO:0051036 | regulation of endosome size(GO:0051036) |
| 0.0 | 0.3 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.1 | 0.2 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 0.0 | 0.2 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) |
| 0.0 | 0.2 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.0 | 0.2 | GO:1904116 | response to vasopressin(GO:1904116) |
| 0.0 | 0.2 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.0 | 0.2 | GO:0071763 | nuclear membrane organization(GO:0071763) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.3 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.0 | 0.2 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.0 | 0.2 | GO:0071203 | WASH complex(GO:0071203) |
| 0.0 | 0.1 | GO:1990812 | growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812) |
| 0.0 | 0.1 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.0 | 0.1 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.0 | 0.1 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.0 | 0.1 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.0 | 0.1 | GO:0000813 | ESCRT I complex(GO:0000813) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 0.2 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.0 | 0.2 | GO:0051378 | serotonin binding(GO:0051378) |
| 0.0 | 0.1 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 0.0 | 0.1 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.0 | 0.1 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.0 | 0.1 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.0 | 0.1 | GO:0016842 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) amidine-lyase activity(GO:0016842) |
| 0.0 | 0.1 | GO:0005042 | netrin receptor activity(GO:0005042) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |