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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Tfap2e

Z-value: 0.23

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Transcription factors associated with Tfap2e

Gene Symbol Gene ID Gene Info
ENSRNOG00000027595 transcription factor AP-2 epsilon

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2ern6_v1_chr5_-_144761787_144761787-0.454.4e-01Click!

Activity profile of Tfap2e motif

Sorted Z-values of Tfap2e motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_3793985 0.13 ENSRNOT00000049540
ENSRNOT00000086293
RT1 class I, locus CE16
chr15_+_108908607 0.07 ENSRNOT00000089455
Zic family member 2
chr10_+_86340940 0.07 ENSRNOT00000073486
phenylethanolamine-N-methyltransferase
chr1_+_266143818 0.06 ENSRNOT00000026987
SUFU negative regulator of hedgehog signaling
chr1_+_81499821 0.04 ENSRNOT00000027100
Ly6/Plaur domain containing 3
chr4_+_140247313 0.04 ENSRNOT00000040255
ENSRNOT00000064025
ENSRNOT00000041130
ENSRNOT00000043646
inositol 1,4,5-trisphosphate receptor, type 1
chr1_+_98440186 0.04 ENSRNOT00000024150
IgLON family member 5
chr4_-_67520356 0.03 ENSRNOT00000014604
B-Raf proto-oncogene, serine/threonine kinase
chr3_+_5709236 0.03 ENSRNOT00000061201
ENSRNOT00000070887
dopamine beta-hydroxylase
chr19_-_19832812 0.02 ENSRNOT00000084657
poly(A) RNA polymerase D5, non-canonical
chr6_+_29012207 0.02 ENSRNOT00000079077
ATPase family, AAA domain containing 2B
chr12_+_44931494 0.02 ENSRNOT00000001498
replication factor C subunit 5
chr2_+_3400977 0.02 ENSRNOT00000093593
multiple C2 and transmembrane domain containing 1
chr10_+_15485905 0.02 ENSRNOT00000027609
transmembrane protein 8A
chr11_-_57993548 0.01 ENSRNOT00000002957
nectin cell adhesion molecule 3
chr10_-_98018014 0.01 ENSRNOT00000005367
FAM20A, golgi associated secretory pathway pseudokinase
chr4_+_120133713 0.01 ENSRNOT00000017240
GATA binding protein 2
chr1_+_154377447 0.01 ENSRNOT00000084268
ENSRNOT00000092086
ENSRNOT00000091470
ENSRNOT00000025415
phosphatidylinositol binding clathrin assembly protein
chr14_+_81819415 0.01 ENSRNOT00000018515
ENSRNOT00000075863
ENSRNOT00000077060
Max dimerization protein 4
chr15_-_88670349 0.01 ENSRNOT00000012881
ring finger protein 219
chr19_-_19832459 0.01 ENSRNOT00000067582
poly(A) RNA polymerase D5, non-canonical
chr6_+_29012007 0.01 ENSRNOT00000085612
ATPase family, AAA domain containing 2B
chr8_+_108958046 0.01 ENSRNOT00000079618
ENSRNOT00000066917
stromal antigen 1
chr2_+_189169877 0.01 ENSRNOT00000028225
Src homology 2 domain containing E
chrX_-_157095274 0.01 ENSRNOT00000084088
ATP binding cassette subfamily D member 1
chr18_-_40716686 0.01 ENSRNOT00000000172
cysteine dioxygenase type 1
chr19_+_14352411 0.01 ENSRNOT00000067519
HMG-box containing 4
chr1_-_260460791 0.01 ENSRNOT00000018179
tolloid-like 2
chr1_+_78933372 0.01 ENSRNOT00000029810
coiled-coil domain containing 8
chr16_-_54137485 0.01 ENSRNOT00000014202
pericentriolar material 1
chr4_-_64831233 0.01 ENSRNOT00000079285
diacylglycerol kinase, iota
chr10_+_83231409 0.01 ENSRNOT00000006230
speckle type BTB/POZ protein
chr10_+_105156632 0.00 ENSRNOT00000086288
galanin receptor 2
chr20_-_1984737 0.00 ENSRNOT00000040232
ENSRNOT00000051634
ENSRNOT00000079445
gamma-aminobutyric acid type B receptor subunit 1
chr17_-_35037076 0.00 ENSRNOT00000090946
dual specificity phosphatase 22
chr17_+_11953552 0.00 ENSRNOT00000090782
receptor tyrosine kinase-like orphan receptor 2
chr8_-_50531423 0.00 ENSRNOT00000090985
ENSRNOT00000074942
apolipoprotein C3
chr7_-_77162148 0.00 ENSRNOT00000008350
Kruppel-like factor 10

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2e

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0042414 epinephrine metabolic process(GO:0042414)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0034774 secretory granule lumen(GO:0034774)