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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Tfap2b

Z-value: 0.31

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Transcription factors associated with Tfap2b

Gene Symbol Gene ID Gene Info
ENSRNOG00000011823 transcription factor AP-2 beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2brn6_v1_chr9_+_25410669_25410717-0.088.9e-01Click!

Activity profile of Tfap2b motif

Sorted Z-values of Tfap2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_123179644 0.15 ENSRNOT00000028835
leucine zipper tumor suppressor family member 3
chr3_+_155160481 0.14 ENSRNOT00000021133
protein phosphatase 1, regulatory subunit 16B
chr6_-_99783047 0.12 ENSRNOT00000009028
spectrin, beta, erythrocytic
chr10_-_85684138 0.11 ENSRNOT00000017989
phosphatidylinositol-5-phosphate 4-kinase type 2 beta
chr17_+_70684539 0.11 ENSRNOT00000025700
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr17_+_70684134 0.11 ENSRNOT00000025731
ENSRNOT00000068354
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_+_78876205 0.10 ENSRNOT00000022610
paraneoplastic Ma antigen family-like 2
chr19_+_46761570 0.09 ENSRNOT00000058779
WW domain-containing oxidoreductase
chr1_+_87045796 0.09 ENSRNOT00000027620
galectin 7
chr7_+_130498199 0.09 ENSRNOT00000092684
ENSRNOT00000092431
SH3 and multiple ankyrin repeat domains 3
chr1_+_261337594 0.09 ENSRNOT00000019874
phosphatidylinositol 4-kinase type 2 alpha
chr5_+_63781801 0.09 ENSRNOT00000008302
nuclear receptor subfamily 4, group A, member 3
chr1_-_219422268 0.09 ENSRNOT00000025092
carnosine synthase 1
chr2_+_189629297 0.08 ENSRNOT00000049810
DENN domain containing 4B
chr10_+_30833914 0.07 ENSRNOT00000035346
ENSRNOT00000079437
clathrin interactor 1
chr1_-_142164007 0.07 ENSRNOT00000078982
mannosidase, alpha, class 2A, member 2
chr7_-_140546908 0.07 ENSRNOT00000077502
lysine methyltransferase 2D
chr19_-_55490426 0.07 ENSRNOT00000081800
CBFA2/RUNX1 translocation partner 3
chr4_+_123801174 0.07 ENSRNOT00000029055
similar to chromosome 3 open reading frame 20
chr11_-_83926524 0.06 ENSRNOT00000041777
ENSRNOT00000040029
eukaryotic translation initiation factor 4 gamma, 1
chr8_+_48805684 0.06 ENSRNOT00000064041
B-cell CLL/lymphoma 9-like
chr5_+_150833819 0.06 ENSRNOT00000056170
EYA transcriptional coactivator and phosphatase 3
chr7_-_118332577 0.06 ENSRNOT00000090370
RNA binding protein, fox-1 homolog 2
chr8_-_131899023 0.06 ENSRNOT00000034690
zinc finger protein 445
chr20_+_3823596 0.06 ENSRNOT00000087670
retinoid X receptor beta
chr5_+_59348639 0.06 ENSRNOT00000084031
ENSRNOT00000060264
reversion-inducing-cysteine-rich protein with kazal motifs
chr5_-_155381732 0.06 ENSRNOT00000033670
zinc finger and BTB domain containing 40
chr4_-_150616895 0.05 ENSRNOT00000073562
ankyrin repeat domain 26
chr20_+_3827367 0.05 ENSRNOT00000079967
retinoid X receptor beta
chr4_-_88649216 0.05 ENSRNOT00000058626
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr17_-_10208360 0.05 ENSRNOT00000087397
unc-5 netrin receptor A
chr1_-_142164263 0.05 ENSRNOT00000016281
mannosidase, alpha, class 2A, member 2
chrX_+_68782872 0.05 ENSRNOT00000075995
StAR-related lipid transfer domain containing 8
chr6_+_26566494 0.05 ENSRNOT00000079292
general transcription factor IIIC subunit 2
chr3_-_15433252 0.05 ENSRNOT00000008817
LIM homeobox 6
chr2_+_116028781 0.05 ENSRNOT00000089477
polyhomeotic homolog 3
chr18_-_68551558 0.05 ENSRNOT00000016369
RAB27B, member RAS oncogene family
chr1_+_222519615 0.05 ENSRNOT00000083585
REST corepressor 2
chr19_+_37568113 0.05 ENSRNOT00000023710
family with sequence similarity 65, member A
chr7_-_116781766 0.04 ENSRNOT00000010084
MAF bZIP transcription factor A
chr9_+_54212767 0.04 ENSRNOT00000078073
ENSRNOT00000090026
glutaminase
chr1_+_154377447 0.04 ENSRNOT00000084268
ENSRNOT00000092086
ENSRNOT00000091470
ENSRNOT00000025415
phosphatidylinositol binding clathrin assembly protein
chr10_+_17421075 0.04 ENSRNOT00000047011
serine/threonine kinase 10
chr20_-_31072469 0.04 ENSRNOT00000082448
eukaryotic translation initiation factor 4E binding protein 2
chr5_-_136965191 0.04 ENSRNOT00000056842
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
chr10_-_73787083 0.04 ENSRNOT00000035280
mediator complex subunit 13
chr3_+_3310954 0.04 ENSRNOT00000061773
potassium sodium-activated channel subfamily T member 1
chr14_+_64686793 0.04 ENSRNOT00000005894
ENSRNOT00000036646
adhesion G protein-coupled receptor A3
chr1_-_48891130 0.04 ENSRNOT00000083884

chr9_+_16749809 0.04 ENSRNOT00000028786
cullin 9
chr17_+_76306585 0.04 ENSRNOT00000065978
dehydrogenase E1 and transketolase domain containing 1
chr10_+_13145099 0.04 ENSRNOT00000091287
serine/arginine repetitive matrix 2
chr10_-_62287189 0.04 ENSRNOT00000004365
WD repeat domain 81
chr5_+_151436464 0.04 ENSRNOT00000012463
mitogen-activated protein kinase kinase kinase 6
chr19_-_55423052 0.04 ENSRNOT00000019528
ENSRNOT00000079641
galactosamine (N-acetyl)-6-sulfatase
chr12_-_30810964 0.03 ENSRNOT00000001235
ENSRNOT00000093237
ENSRNOT00000077977
splicing factor SWAP homolog
chr4_+_157523770 0.03 ENSRNOT00000055985
ENSRNOT00000023240
zinc finger protein 384
chr15_-_28611946 0.03 ENSRNOT00000016288
SPT16 homolog, facilitates chromatin remodeling subunit
chr8_-_111984572 0.03 ENSRNOT00000014519
transmembrane protein 108
chr1_+_87045335 0.03 ENSRNOT00000084393
galectin 7
chrX_+_120859968 0.03 ENSRNOT00000085185
WD repeat domain 44
chr20_+_5067330 0.03 ENSRNOT00000037482
lymphocyte antigen 6 complex, locus G6E
chr15_+_19690194 0.03 ENSRNOT00000010612
serine/threonine/tyrosine interacting protein
chr12_-_37682964 0.03 ENSRNOT00000001421
similar to hypothetical protein FLJ38663
chr1_+_177764445 0.03 ENSRNOT00000037185
Ras association domain family member 10
chr8_-_56696523 0.03 ENSRNOT00000080043
zinc finger CCCH type containing 12C
chr5_-_74191167 0.03 ENSRNOT00000088169
erythrocyte membrane protein band 4.1 like 4B
chr4_+_7662019 0.03 ENSRNOT00000014023
family with sequence similarity 126, member A
chrX_-_114232939 0.03 ENSRNOT00000042639
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr4_+_140092352 0.03 ENSRNOT00000008892
SET domain and mariner transposase fusion gene
chr11_-_47113993 0.03 ENSRNOT00000034940
zinc finger and BTB domain containing 11
chr9_+_17086475 0.03 ENSRNOT00000025660
tight junction associated protein 1
chr17_-_63994169 0.03 ENSRNOT00000075651
cholinergic receptor, muscarinic 3
chr7_-_63578490 0.03 ENSRNOT00000007295
Ras association domain family member 3
chr8_+_118821729 0.03 ENSRNOT00000028409
SET domain containing 2
chr1_-_162300515 0.03 ENSRNOT00000031161
ubiquitin specific peptidase 35
chr3_-_162581610 0.03 ENSRNOT00000079324
zinc finger, MYND-type containing 8
chr13_+_51795867 0.02 ENSRNOT00000006747
ubiquitin-conjugating enzyme E2T
chr8_-_56696968 0.02 ENSRNOT00000016637
zinc finger CCCH type containing 12C
chr3_-_57913999 0.02 ENSRNOT00000090426
solute carrier family 25 member 12
chr2_-_234296145 0.02 ENSRNOT00000014155
ELOVL fatty acid elongase 6
chr1_+_1784078 0.02 ENSRNOT00000020098
large tumor suppressor kinase 1
chr17_-_9695292 0.02 ENSRNOT00000036162
proline rich 7 (synaptic)
chr1_-_127599257 0.02 ENSRNOT00000018436
ankyrin repeat and SOCS box-containing 7
chrX_+_14498283 0.02 ENSRNOT00000092143
X-linked Kx blood group
chr13_-_72869396 0.02 ENSRNOT00000093563
similar to 6820428L09 protein
chr3_+_79729739 0.02 ENSRNOT00000084833
kelch repeat and BTB domain containing 4
chr7_-_36000906 0.02 ENSRNOT00000011178
plexin C1
chr8_+_63036976 0.02 ENSRNOT00000011383
stomatin like 1
chr7_-_119185238 0.02 ENSRNOT00000007598
FAD-dependent oxidoreductase domain containing 2
chr20_+_3556560 0.02 ENSRNOT00000085635
discoidin domain receptor tyrosine kinase 1
chr13_-_49169918 0.01 ENSRNOT00000000036
transmembrane and coiled-coil domain family 2
chr6_-_110904288 0.01 ENSRNOT00000014645
interferon regulatory factor 2 binding protein-like
chr7_+_78092037 0.01 ENSRNOT00000050753
regulating synaptic membrane exocytosis 2
chr13_-_53108713 0.01 ENSRNOT00000035404
similar to hypothetical protein FLJ10901
chr16_-_61091169 0.01 ENSRNOT00000016328
dual specificity phosphatase 4
chr1_+_221735517 0.01 ENSRNOT00000028628
ENSRNOT00000044866
splicing factor 1
chr2_+_189169877 0.01 ENSRNOT00000028225
Src homology 2 domain containing E
chr19_+_37252843 0.01 ENSRNOT00000021145
E2F transcription factor 4
chr8_-_48652064 0.01 ENSRNOT00000030745
ENSRNOT00000083490
C2CD2-like
chr13_-_60496511 0.01 ENSRNOT00000004495
cell division cycle 73
chr10_+_86564928 0.01 ENSRNOT00000039892
leucine rich repeat containing 3C
chr9_+_82053581 0.01 ENSRNOT00000086375
wingless-type MMTV integration site family, member 10A
chr9_+_100888501 0.01 ENSRNOT00000025529
autophagy related 4B, cysteine peptidase
chr10_+_94207336 0.01 ENSRNOT00000010816
potassium voltage-gated channel subfamily H member 6
chr20_-_29511382 0.01 ENSRNOT00000085026
DNA-damage-inducible transcript 4
chr19_+_57614628 0.01 ENSRNOT00000026617
glyceronephosphate O-acyltransferase
chr3_+_172385672 0.01 ENSRNOT00000090989
GNAS complex locus
chr3_+_46286712 0.01 ENSRNOT00000085563
membrane associated ring-CH-type finger 7
chr3_+_13838304 0.01 ENSRNOT00000025067
heat shock protein family A member 5
chr6_+_136042059 0.01 ENSRNOT00000088784
microtubule affinity regulating kinase 3
chr4_-_147592699 0.01 ENSRNOT00000013831
Raf-1 proto-oncogene, serine/threonine kinase
chr19_-_57614558 0.01 ENSRNOT00000025948
similar to RIKEN cDNA 0610039J04
chr3_-_52998650 0.01 ENSRNOT00000009988
similar to 40S ribosomal protein S3
chr3_-_170040953 0.01 ENSRNOT00000005866
cerebellin 4 precursor
chr6_+_93281408 0.00 ENSRNOT00000009610
FERM domain containing 6
chr18_+_54206651 0.00 ENSRNOT00000073295
chondroitin sulfate synthase 3
chr20_+_6973398 0.00 ENSRNOT00000041665
FYVE, RhoGEF and PH domain containing 2
chr7_-_77162148 0.00 ENSRNOT00000008350
Kruppel-like factor 10
chr16_+_55834458 0.00 ENSRNOT00000086141

chr10_-_35800120 0.00 ENSRNOT00000004361
mastermind-like transcriptional coactivator 1
chr2_-_243224883 0.00 ENSRNOT00000014139
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr12_-_30501860 0.00 ENSRNOT00000001227
chaperonin containing TCP1 subunit 6A
chr14_+_86101277 0.00 ENSRNOT00000018846
AE binding protein 1
chr3_-_3594475 0.00 ENSRNOT00000064861
RGD1564379
chr3_-_80933283 0.00 ENSRNOT00000007771
cAMP responsive element binding protein 3-like 1
chr1_+_68436917 0.00 ENSRNOT00000088586
leucyl-cystinyl aminopeptidase
chr1_-_59347472 0.00 ENSRNOT00000017718
leucyl and cystinyl aminopeptidase
chr1_+_78933372 0.00 ENSRNOT00000029810
coiled-coil domain containing 8
chr5_-_159293673 0.00 ENSRNOT00000009081
peptidyl arginine deiminase 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0045575 basophil activation(GO:0045575)
0.0 0.1 GO:1900623 regulation of mast cell cytokine production(GO:0032763) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.1 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.0 0.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0014731 spectrin(GO:0008091) spectrin-associated cytoskeleton(GO:0014731)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.0 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)