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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Tead3_Tead4
Z-value: 0.51
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Transcription factors associated with Tead3_Tead4
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tead3 | rn6_v1_chr20_-_7930929_7930929 | -0.76 | 1.3e-01 | Click! |
| Tead4 | rn6_v1_chr4_-_161587222_161587222 | -0.21 | 7.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_161433410 Show fit | 0.43 |
ENSRNOT00000024657
|
solute carrier family 12 member 5 |
|
| chr20_-_12820466 Show fit | 0.21 |
ENSRNOT00000001699
|
formimidoyltransferase cyclodeaminase |
|
| chrX_+_22247088 Show fit | 0.18 |
ENSRNOT00000079802
|
IQ motif and Sec7 domain 2 |
|
| chr3_+_21764377 Show fit | 0.18 |
ENSRNOT00000063938
|
G protein-coupled receptor 21 |
|
| chr11_-_64952687 Show fit | 0.17 |
ENSRNOT00000087892
|
popeye domain containing 2 |
|
| chr7_-_52404774 Show fit | 0.15 |
ENSRNOT00000082100
|
neuron navigator 3 |
|
| chr8_+_48438259 Show fit | 0.15 |
ENSRNOT00000059813
|
membrane frizzled-related protein |
|
| chr5_+_74649765 Show fit | 0.14 |
ENSRNOT00000075952
|
paralemmin 2 |
|
| chr4_+_120672152 Show fit | 0.14 |
ENSRNOT00000077231
|
monoglyceride lipase |
|
| chr1_+_248402980 Show fit | 0.13 |
ENSRNOT00000043517
|
coiled-coil-helix-coiled-coil-helix domain containing 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Tead3_Tead4
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.1 | 0.2 | GO:0043606 | formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606) |
| 0.1 | 0.2 | GO:0060931 | sinoatrial node cell development(GO:0060931) |
| 0.0 | 0.2 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
| 0.0 | 0.1 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
| 0.0 | 0.1 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.0 | 0.1 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.0 | 0.1 | GO:1901726 | negative regulation of histone deacetylase activity(GO:1901726) |
| 0.0 | 0.1 | GO:0045887 | positive regulation of synaptic growth at neuromuscular junction(GO:0045887) regulation of protein geranylgeranylation(GO:2000539) positive regulation of protein geranylgeranylation(GO:2000541) |
| 0.0 | 0.1 | GO:0006543 | glutamine catabolic process(GO:0006543) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.0 | 0.1 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.0 | 0.1 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 0.0 | 0.1 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 0.1 | GO:0005869 | dynactin complex(GO:0005869) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 0.2 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) |
| 0.0 | 0.2 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
| 0.0 | 0.1 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.0 | 0.1 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.0 | 0.1 | GO:0015226 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) antibiotic transporter activity(GO:0042895) |
| 0.0 | 0.1 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.0 | 0.1 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.0 | 0.1 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.0 | 0.1 | GO:0070728 | leucine binding(GO:0070728) |