Project
GSE49485: Hypoxia transcriptome sequencing of rat brain.
Navigation
Downloads
Results for Tcf7l1
Z-value: 0.69
Motif logo
Transcription factors associated with Tcf7l1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tcf7l1 | rn6_v1_chr4_-_100660140_100660140 | 0.43 | 4.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_-_93826665 Show fit | 0.39 |
ENSRNOT00000011344
|
TNF receptor superfamily member 11B |
|
| chr20_-_27208041 Show fit | 0.25 |
ENSRNOT00000084720
|
RUN and FYVE domain containing 2 |
|
| chr20_-_31598118 Show fit | 0.21 |
ENSRNOT00000046537
|
collagen type XIII alpha 1 chain |
|
| chr15_-_41338284 Show fit | 0.20 |
ENSRNOT00000077225
|
TNF receptor superfamily member 19 |
|
| chr2_-_142686577 Show fit | 0.18 |
ENSRNOT00000014562
|
NHL repeat containing 3 |
|
| chr10_-_37645802 Show fit | 0.18 |
ENSRNOT00000008022
|
transcription factor 7 (T-cell specific, HMG-box) |
|
| chr17_+_12762752 Show fit | 0.18 |
ENSRNOT00000044842
|
DIRAS family GTPase 2 |
|
| chr7_-_140090922 Show fit | 0.17 |
ENSRNOT00000014456
|
lactalbumin, alpha |
|
| chr3_+_21764377 Show fit | 0.16 |
ENSRNOT00000063938
|
G protein-coupled receptor 21 |
|
| chr2_-_165739874 Show fit | 0.16 |
ENSRNOT00000014384
|
karyopherin subunit alpha 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Tcf7l1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0042489 | negative regulation of odontogenesis of dentin-containing tooth(GO:0042489) |
| 0.1 | 0.2 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
| 0.0 | 0.2 | GO:0046351 | disaccharide biosynthetic process(GO:0046351) |
| 0.0 | 0.2 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
| 0.0 | 0.2 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.0 | 0.2 | GO:0042159 | lipoprotein catabolic process(GO:0042159) |
| 0.0 | 0.2 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.1 | GO:1900827 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.0 | 0.1 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
| 0.0 | 0.1 | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0044317 | rod spherule(GO:0044317) |
| 0.0 | 0.1 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.0 | 0.1 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.0 | 0.1 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 0.1 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 0.1 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
| 0.0 | 0.1 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 0.1 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.0 | 0.1 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.0 | 0.1 | GO:0044294 | dendritic growth cone(GO:0044294) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 0.2 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) |
| 0.1 | 0.2 | GO:0004507 | steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783) |
| 0.0 | 0.2 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 0.1 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 0.0 | 0.1 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.0 | 0.1 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.0 | 0.1 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.0 | 0.1 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.0 | 0.1 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.0 | 0.1 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |