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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Tcf7_Tcf7l2

Z-value: 1.06

Motif logo

Transcription factors associated with Tcf7_Tcf7l2

Gene Symbol Gene ID Gene Info
ENSRNOG00000005872 transcription factor 7 (T-cell specific, HMG-box)
ENSRNOG00000049232 transcription factor 7 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf7rn6_v1_chr10_-_37645802_376458020.237.1e-01Click!
AABR07007000.1rn6_v1_chr1_-_276012351_276012351-0.148.2e-01Click!

Activity profile of Tcf7_Tcf7l2 motif

Sorted Z-values of Tcf7_Tcf7l2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_112368557 0.62 ENSRNOT00000075017

chr17_+_48436720 0.62 ENSRNOT00000074309

chr11_+_67555658 0.60 ENSRNOT00000039075
cystatin A (stefin A)
chr3_+_151691515 0.60 ENSRNOT00000052236

chr1_+_168668707 0.60 ENSRNOT00000015108

chr6_+_127941526 0.56 ENSRNOT00000033897
Ab1-233
chr10_-_109840047 0.54 ENSRNOT00000054947
NOTUM, palmitoleoyl-protein carboxylesterase
chr3_-_76012929 0.50 ENSRNOT00000085199

chr15_-_41338284 0.45 ENSRNOT00000077225
TNF receptor superfamily member 19
chr17_+_43868191 0.44 ENSRNOT00000059403
butyrophilin, subfamily 2, member A2
chr10_-_88152064 0.40 ENSRNOT00000019477
keratin 16
chr9_+_12346117 0.37 ENSRNOT00000074599

chr2_+_71753816 0.36 ENSRNOT00000025809

chr9_+_12420368 0.36 ENSRNOT00000071620

chr17_+_22619891 0.35 ENSRNOT00000060403
androgen-dependent TFPI-regulating protein
chr6_+_106039991 0.34 ENSRNOT00000088917
signal-induced proliferation-associated 1 like 1
chr1_-_16989482 0.34 ENSRNOT00000072759

chr2_-_170460754 0.34 ENSRNOT00000013009
SLIT and NTRK-like family, member 3
chr2_+_144861455 0.32 ENSRNOT00000093284
ENSRNOT00000019748
ENSRNOT00000072110
doublecortin-like kinase 1
chr1_+_252409268 0.31 ENSRNOT00000026219
lipase, family member M
chr19_-_21970103 0.28 ENSRNOT00000074210

chr7_-_15821927 0.27 ENSRNOT00000050658
similar to zinc finger protein 101
chr4_+_22859622 0.27 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr2_+_179952227 0.27 ENSRNOT00000015081
platelet derived growth factor C
chr14_+_11988671 0.27 ENSRNOT00000003207
RasGEF domain family, member 1B
chr17_-_86873003 0.26 ENSRNOT00000061526
RIKEN cDNA 6720489N17 gene
chr13_-_26768708 0.25 ENSRNOT00000092763
BCL2, apoptosis regulator
chr7_+_20462081 0.25 ENSRNOT00000088383

chr7_-_143538579 0.25 ENSRNOT00000081518
keratin 79
chr8_+_49441106 0.25 ENSRNOT00000030152
sodium voltage-gated channel beta subunit 4
chr1_-_82004538 0.24 ENSRNOT00000087572
POU class 2 homeobox 2
chr5_+_74766636 0.24 ENSRNOT00000030913

chr3_-_2719135 0.24 ENSRNOT00000080257
lipocalin 12
chr3_-_2719513 0.24 ENSRNOT00000020997
lipocalin 12
chr5_+_48456757 0.23 ENSRNOT00000091482
serine and arginine rich splicing factor 12
chr13_-_82005741 0.23 ENSRNOT00000076404
methyltransferase like 11B
chr1_-_170186462 0.22 ENSRNOT00000035798
olfactory receptor 202
chr16_+_3851270 0.22 ENSRNOT00000014964
placenta-specific 9
chr13_-_82006005 0.22 ENSRNOT00000039581
methyltransferase like 11B
chr6_+_108123816 0.22 ENSRNOT00000089242
ENSRNOT00000063900
basal body orientation factor 1
chr14_-_92495894 0.21 ENSRNOT00000064483
cordon-bleu WH2 repeat protein
chr4_+_102426224 0.21 ENSRNOT00000073768
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 pseudogene
chr1_+_128614138 0.21 ENSRNOT00000076227
ENSRNOT00000078707
tetratricopeptide repeat domain 23
chr1_+_61522298 0.21 ENSRNOT00000029111
zinc finger protein 51
chr3_+_21764377 0.20 ENSRNOT00000063938
G protein-coupled receptor 21
chr3_+_72329967 0.20 ENSRNOT00000090256
solute carrier family 43, member 3
chr10_-_37645802 0.20 ENSRNOT00000008022
transcription factor 7 (T-cell specific, HMG-box)
chr3_+_149741312 0.20 ENSRNOT00000070854
high mobility group protein B1-like
chr10_-_40994872 0.20 ENSRNOT00000058640
similar to High mobility group protein 1 (HMG-1)
chr3_-_153321352 0.19 ENSRNOT00000064824
RB transcriptional corepressor like 1
chr9_+_99795678 0.19 ENSRNOT00000056601
olfactory receptor 1353
chr4_-_169999873 0.18 ENSRNOT00000011697
glutamate ionotropic receptor NMDA type subunit 2B
chr12_-_37682964 0.17 ENSRNOT00000001421
similar to hypothetical protein FLJ38663
chr8_+_44061894 0.17 ENSRNOT00000084416
zinc finger protein 202
chr10_+_38104558 0.17 ENSRNOT00000067809
follistatin-like 4
chr2_-_40386669 0.17 ENSRNOT00000014074
ELOVL fatty acid elongase 7
chr8_+_64531594 0.17 ENSRNOT00000036798
GRAM domain containing 2
chr7_+_141642777 0.17 ENSRNOT00000079811

chr3_-_25212049 0.16 ENSRNOT00000040023
LDL receptor related protein 1B
chr1_-_219422268 0.16 ENSRNOT00000025092
carnosine synthase 1
chrX_-_25628272 0.16 ENSRNOT00000086414
midline 1
chr4_+_92431710 0.16 ENSRNOT00000049438
high mobility group protein B1-like
chr1_-_248377093 0.16 ENSRNOT00000067612
glycine decarboxylase
chr17_-_88095729 0.15 ENSRNOT00000025140
enkurin, TRPC channel interacting protein
chr20_-_27247309 0.15 ENSRNOT00000037409
RUN and FYVE domain-containing protein 2-like
chr13_-_107886476 0.15 ENSRNOT00000077282
potassium two pore domain channel subfamily K member 2
chr1_+_81474553 0.14 ENSRNOT00000083493
pleckstrin homology-like domain, family B, member 3
chr6_-_61405195 0.14 ENSRNOT00000008655
leucine rich repeat neuronal 3
chr3_-_44177689 0.14 ENSRNOT00000006387
cytohesin 1 interacting protein
chr1_+_255710658 0.14 ENSRNOT00000031545

chr1_+_61786900 0.14 ENSRNOT00000090287

chr6_-_76652757 0.14 ENSRNOT00000042177
ferritin light chain 2
chr7_-_116201756 0.14 ENSRNOT00000091401
cytochrome P450, family 11, subfamily b, polypeptide 2
chr9_+_18001105 0.14 ENSRNOT00000071814

chr4_-_161278293 0.13 ENSRNOT00000050332

chr15_-_64191115 0.13 ENSRNOT00000013868
40S ribosomal protein S17-like
chr8_-_53758774 0.13 ENSRNOT00000068040
ankyrin repeat and kinase domain containing 1
chr3_+_149790856 0.13 ENSRNOT00000075275
high mobility group protein B1-like
chr13_+_83996080 0.13 ENSRNOT00000004403
ENSRNOT00000070958
Cd247 molecule
chr9_-_9585865 0.13 ENSRNOT00000073926
adhesion G protein-coupled receptor E1
chr12_-_51965779 0.13 ENSRNOT00000056733
replication protein A3-like
chr8_+_71591360 0.13 ENSRNOT00000090096
casein kinase 1, gamma 1
chr4_+_150199627 0.13 ENSRNOT00000052259

chr8_-_47404010 0.13 ENSRNOT00000038647
transmembrane protein 136
chr3_+_152226070 0.13 ENSRNOT00000073201

chr7_-_70661891 0.13 ENSRNOT00000010240
inhibin beta C subunit
chr7_-_140417530 0.13 ENSRNOT00000077884
FK506 binding protein 11
chr5_+_148066062 0.13 ENSRNOT00000084118

chr7_-_140090922 0.12 ENSRNOT00000014456
lactalbumin, alpha
chr2_+_189993262 0.12 ENSRNOT00000016034
S100 calcium binding protein A3
chr6_-_122572925 0.12 ENSRNOT00000090869

chr6_-_111329882 0.12 ENSRNOT00000074480
isthmin 2
chr8_+_103774358 0.12 ENSRNOT00000014481
5'-3' exoribonuclease 1
chr14_-_114047527 0.12 ENSRNOT00000083199

chr3_+_176494768 0.12 ENSRNOT00000040270
collagen type XX alpha 1 chain
chr4_+_108301129 0.12 ENSRNOT00000007993
leucine rich repeat transmembrane neuronal 1
chr1_-_52894832 0.11 ENSRNOT00000016471
T brachyury transcription factor
chr9_-_41996077 0.11 ENSRNOT00000087372

chr10_-_98294522 0.11 ENSRNOT00000005489
ATP binding cassette subfamily A member 8
chr12_-_9988618 0.11 ENSRNOT00000087449
RAS-like family 11 member A
chr3_-_158328881 0.11 ENSRNOT00000044466
protein tyrosine phosphatase, receptor type, T
chr2_-_208633945 0.11 ENSRNOT00000049155
primary cilia formation
chr3_-_146470293 0.11 ENSRNOT00000009627
acyl-CoA synthetase short-chain family member 1
chr18_+_87637608 0.11 ENSRNOT00000070851
zinc finger protein 120-like
chr1_-_120893997 0.11 ENSRNOT00000081028

chr1_-_263431290 0.11 ENSRNOT00000022633
solute carrier family 25 member 28
chr5_+_74727494 0.11 ENSRNOT00000076683

chrX_-_115375492 0.11 ENSRNOT00000007194

chr10_-_74119009 0.11 ENSRNOT00000085712
ENSRNOT00000006926
DEAH-box helicase 40
chr15_-_82482009 0.11 ENSRNOT00000011926
dachshund family transcription factor 1
chr7_-_139835876 0.11 ENSRNOT00000014258
olfactory receptor 1877
chr8_-_87315955 0.10 ENSRNOT00000081437
filamin A interacting protein 1
chr2_-_232373409 0.10 ENSRNOT00000041479

chr17_-_17947777 0.10 ENSRNOT00000036876
ring finger protein 144B
chr14_-_2610929 0.10 ENSRNOT00000036442
coiled-coil domain containing 18
chr15_+_28439317 0.10 ENSRNOT00000060519
similar to ribosomal protein L31
chr12_-_11808977 0.10 ENSRNOT00000071795

chrX_-_152642531 0.10 ENSRNOT00000085037
gamma-aminobutyric acid type A receptor alpha3 subunit
chr4_-_28310178 0.10 ENSRNOT00000084021
similar to OEF2
chr2_-_98610368 0.10 ENSRNOT00000011641
zinc finger homeobox 4
chr1_+_248210041 0.10 ENSRNOT00000047024

chr6_+_106084815 0.10 ENSRNOT00000058195
signal-induced proliferation-associated 1 like 1
chr14_-_62646110 0.10 ENSRNOT00000002992
glucosamine-6-phosphate deaminase 2
chr11_+_67101714 0.10 ENSRNOT00000078936
CD86 molecule
chr8_+_94693290 0.10 ENSRNOT00000013908
cytochrome b5 reductase 4
chr8_+_5606592 0.10 ENSRNOT00000011727
matrix metallopeptidase 12
chr7_+_63352046 0.09 ENSRNOT00000046453
similar to ribosomal protein S10
chr9_+_60039297 0.09 ENSRNOT00000016262
solute carrier family 39 member 10
chr12_-_37688743 0.09 ENSRNOT00000030251
similar to hypothetical protein FLJ38663
chr17_+_88095830 0.09 ENSRNOT00000045984
threonine synthase-like 1
chr9_-_73799427 0.09 ENSRNOT00000067589
KAT8 regulatory NSL complex subunit 1-like
chr8_+_22648323 0.09 ENSRNOT00000013165
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr13_+_44475970 0.09 ENSRNOT00000024602
ENSRNOT00000091645
cyclin T2
chr8_+_58431407 0.09 ENSRNOT00000011974
sarcolipin
chr15_+_48674380 0.09 ENSRNOT00000018762
F-box protein 16
chr12_-_52596076 0.09 ENSRNOT00000056639
checkpoint with forkhead and ring finger domains
chr11_+_20471764 0.09 ENSRNOT00000078127
neural cell adhesion molecule 2
chr14_-_18862407 0.09 ENSRNOT00000003823
C-X-C motif chemokine ligand 6
chr5_-_6083083 0.09 ENSRNOT00000072411
sulfatase 1
chr10_-_25910298 0.08 ENSRNOT00000065633
ENSRNOT00000079646
cyclin G1
chr1_+_199163086 0.08 ENSRNOT00000025646
cardiotrophin 1
chr12_+_19231092 0.08 ENSRNOT00000045379
zinc finger with KRAB and SCAN domains 1
chr19_+_56803382 0.08 ENSRNOT00000036042
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr18_+_46148849 0.08 ENSRNOT00000026724
proline rich 16
chr8_+_56451240 0.08 ENSRNOT00000085278
mitochondrial ribosomal protein L1-like
chr15_-_34612432 0.08 ENSRNOT00000090206
mast cell protease 1-like 1
chr2_-_125323454 0.08 ENSRNOT00000045837
ankyrin repeat domain 50
chr13_-_90641772 0.08 ENSRNOT00000064601
ATPase Na+/K+ transporting subunit alpha 4
chr12_-_13374500 0.08 ENSRNOT00000038577
zinc finger protein 12
chr13_+_70157522 0.08 ENSRNOT00000036906
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr1_-_62316450 0.08 ENSRNOT00000079171

chrX_-_21710341 0.08 ENSRNOT00000091261
RIB43A domain with coiled-coils 1
chr3_-_46726946 0.08 ENSRNOT00000011030
ENSRNOT00000086576
integrin subunit beta 6
chr1_+_224957517 0.08 ENSRNOT00000026033
nuclear RNA export factor 1
chr1_+_80973739 0.08 ENSRNOT00000026088
ENSRNOT00000081983

chr10_+_89285855 0.08 ENSRNOT00000028033
glucose-6-phosphatase, catalytic subunit
chrX_+_135470915 0.08 ENSRNOT00000009637
solute carrier family 25 member 14
chr2_+_207351051 0.08 ENSRNOT00000084302
suppression of tumorigenicity 7-like
chr5_-_77294735 0.08 ENSRNOT00000018209
ENSRNOT00000056900
zinc finger protein 37
chr1_-_141579871 0.08 ENSRNOT00000020002
alanyl aminopeptidase, membrane
chr5_-_147907733 0.08 ENSRNOT00000032558
transmembrane protein 39b
chr17_+_45078556 0.08 ENSRNOT00000088280
zinc finger protein 192
chr7_+_35070284 0.08 ENSRNOT00000009578
nuclear receptor subfamily 2, group C, member 1
chr9_-_17065600 0.07 ENSRNOT00000025638
delta like non-canonical Notch ligand 2
chr1_+_187149453 0.07 ENSRNOT00000082738
xylosyltransferase 1
chr5_+_126254142 0.07 ENSRNOT00000057471
prolyl-tRNA synthetase 2, mitochondrial (putative)
chr11_+_66878658 0.07 ENSRNOT00000003208
ELL associated factor 2
chr10_-_74376270 0.07 ENSRNOT00000079311
glycerophosphodiester phosphodiesterase domain containing 1
chr1_-_31936537 0.07 ENSRNOT00000060971
zinc finger, DHHC-type containing 11
chr4_+_179481263 0.07 ENSRNOT00000021284
electron transfer flavoprotein regulatory factor 1
chr4_-_159697207 0.07 ENSRNOT00000086440
cyclin D2
chr10_+_43446526 0.07 ENSRNOT00000036959
La ribonucleoprotein domain family, member 1
chr13_+_63526486 0.07 ENSRNOT00000003788
BMP/retinoic acid inducible neural specific 3
chr1_+_185863043 0.07 ENSRNOT00000079072
SRY box 6
chr2_+_243422811 0.07 ENSRNOT00000014694
tRNA methyltransferase 10A
chr1_-_88162583 0.07 ENSRNOT00000087411
cation channel sperm associated auxiliary subunit gamma
chr6_-_25211494 0.07 ENSRNOT00000009634
xanthine dehydrogenase
chr6_+_73553210 0.07 ENSRNOT00000006562
A-kinase anchoring protein 6
chr1_+_88457594 0.07 ENSRNOT00000049877
zinc finger protein 260
chr10_+_74413989 0.07 ENSRNOT00000036098
spindle and kinetochore associated complex subunit 2
chr2_-_91497091 0.07 ENSRNOT00000015185
proprotein convertase subtilisin/kexin type 1
chr9_+_92681078 0.07 ENSRNOT00000034152
SP100 nuclear antigen
chr1_-_218100272 0.07 ENSRNOT00000028411
ENSRNOT00000088588
cyclin D1
chr11_+_88732381 0.07 ENSRNOT00000078367
FYVE, RhoGEF and PH domain containing 4
chr1_+_88922433 0.07 ENSRNOT00000045212
NPHS1 nephrin
chr3_+_8451292 0.07 ENSRNOT00000020407
outer dense fiber of sperm tails 2
chr3_-_166993940 0.07 ENSRNOT00000034669
zinc finger protein 217
chr15_-_20822740 0.07 ENSRNOT00000012957
bone morphogenetic protein 4
chr1_-_62558033 0.07 ENSRNOT00000015520
zinc finger protein 40
chr1_+_202432366 0.06 ENSRNOT00000027681
phospholipid phosphatase 4
chr17_+_9736577 0.06 ENSRNOT00000066586
coagulation factor XII
chr4_+_7144669 0.06 ENSRNOT00000077682
ENSRNOT00000014998
IQ motif containing with AAA domain 1 like
chr8_-_87419564 0.06 ENSRNOT00000015365
filamin A interacting protein 1
chrX_-_21710678 0.06 ENSRNOT00000004184
RIB43A domain with coiled-coils 1
chr4_-_161091010 0.06 ENSRNOT00000043708
Sumo1/sentrin/SMT3 specific peptidase 17
chr8_+_76400341 0.06 ENSRNOT00000087382
ENSRNOT00000081072
BCL2/adenovirus E1B interacting protein 2
chr8_+_107882219 0.06 ENSRNOT00000019902
DAZ interacting zinc finger protein 1-like
chr20_-_4390436 0.06 ENSRNOT00000000497
ENSRNOT00000077655
palmitoyl-protein thioesterase 2
chr11_-_61530567 0.06 ENSRNOT00000076277
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr18_-_786674 0.06 ENSRNOT00000021955
centrin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf7_Tcf7l2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.3 GO:0046671 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.2 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.1 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.5 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.2 GO:0048669 somite specification(GO:0001757) collateral sprouting in absence of injury(GO:0048669)
0.0 0.2 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
0.0 0.2 GO:1902951 NMDA selective glutamate receptor signaling pathway(GO:0098989) negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.0 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.1 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) notochord formation(GO:0014028)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.1 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.0 0.2 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0072642 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.4 GO:0051546 keratinization(GO:0031424) keratinocyte migration(GO:0051546)
0.0 0.1 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.0 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.0 0.0 GO:1990478 response to ultrasound(GO:1990478)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.3 GO:0006415 translational termination(GO:0006415)
0.0 0.1 GO:1900747 xanthine catabolic process(GO:0009115) negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.0 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.0 GO:0009080 alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.0 0.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.0 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.0 GO:0046103 inosine biosynthetic process(GO:0046103)
0.0 0.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.0 GO:0008275 gamma-tubulin small complex(GO:0008275)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.2 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0032551 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0 0.0 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.0 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.0 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0089720 caspase binding(GO:0089720)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols