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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Tcf4_Mesp1

Z-value: 0.35

Motif logo

Transcription factors associated with Tcf4_Mesp1

Gene Symbol Gene ID Gene Info
ENSRNOG00000012405 transcription factor 4
ENSRNOG00000014951 mesoderm posterior bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf4rn6_v1_chr18_+_65285318_65285318-0.355.7e-01Click!
Mesp1rn6_v1_chr1_-_141533908_141533908-0.237.1e-01Click!

Activity profile of Tcf4_Mesp1 motif

Sorted Z-values of Tcf4_Mesp1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_2174131 0.79 ENSRNOT00000001313
Purkinje cell protein 2
chr6_+_33885495 0.43 ENSRNOT00000086633
syndecan 1
chr10_+_59529785 0.33 ENSRNOT00000064840
ENSRNOT00000065181
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr7_-_130120579 0.28 ENSRNOT00000044376
mitogen-activated protein kinase 12
chr5_-_21345805 0.28 ENSRNOT00000081296
ENSRNOT00000007802
carbonic anhydrase 8
chr16_-_20807070 0.27 ENSRNOT00000072536
cartilage oligomeric matrix protein
chr5_+_154522119 0.25 ENSRNOT00000072618
E2F transcription factor 2
chr3_-_9037942 0.25 ENSRNOT00000036770
immediate early response 5-like
chr19_-_46167950 0.24 ENSRNOT00000071024

chr3_-_123119460 0.24 ENSRNOT00000028833
arginine vasopressin
chr9_+_16565225 0.21 ENSRNOT00000022307
glycine N-methyltransferase
chr9_-_9985630 0.21 ENSRNOT00000071780
crumbs 3, cell polarity complex component
chr1_+_221673590 0.21 ENSRNOT00000038016
CDC42 binding protein kinase gamma
chr7_-_107634287 0.19 ENSRNOT00000093672
ENSRNOT00000087116
src-like adaptor
chr18_-_3662654 0.18 ENSRNOT00000092854
ENSRNOT00000016167
NPC intracellular cholesterol transporter 1
chr19_+_41482728 0.18 ENSRNOT00000022943
calbindin 2
chr20_+_40618128 0.17 ENSRNOT00000001075
ENSRNOT00000057364
cAMP-dependent protein kinase inhibitor beta
chr9_+_84203072 0.16 ENSRNOT00000018882
sphingosine-1-phosphate phosphatase 2
chr5_+_117052260 0.15 ENSRNOT00000010211
PATJ, crumbs cell polarity complex component
chr16_-_19918644 0.15 ENSRNOT00000083345
ENSRNOT00000023926
plasmalemma vesicle associated protein
chr10_-_88551056 0.15 ENSRNOT00000032737
zinc finger protein 385C
chr10_+_86399827 0.15 ENSRNOT00000009299
growth factor receptor bound protein 7
chr6_-_99783047 0.15 ENSRNOT00000009028
spectrin, beta, erythrocytic
chr16_-_20888907 0.15 ENSRNOT00000027428
homer scaffolding protein 3
chr20_+_5067330 0.15 ENSRNOT00000037482
lymphocyte antigen 6 complex, locus G6E
chr9_+_16314173 0.15 ENSRNOT00000072812
glycine N-methyltransferase-like
chr6_-_11494459 0.14 ENSRNOT00000021570
potassium two pore domain channel subfamily K member 12
chr7_-_123445613 0.14 ENSRNOT00000070937
shisa family member 8
chrX_-_111942749 0.14 ENSRNOT00000087583

chr12_-_48857724 0.13 ENSRNOT00000080783
WSC domain containing 2
chr6_+_3012804 0.13 ENSRNOT00000061980
Rho guanine nucleotide exchange factor 33
chr14_-_82055290 0.13 ENSRNOT00000058062
RGD1560394
chrX_-_157286936 0.12 ENSRNOT00000078100
ATPase plasma membrane Ca2+ transporting 3
chr1_-_264975132 0.12 ENSRNOT00000021748
ladybird homeobox 1
chr20_-_3440769 0.12 ENSRNOT00000084981
immediate early response 3
chr13_+_25778317 0.12 ENSRNOT00000021129
TNF receptor superfamily member 11A
chr17_-_84488480 0.12 ENSRNOT00000000158
ENSRNOT00000075983
nebulette
chr19_-_645937 0.12 ENSRNOT00000016521
carbonic anhydrase 7
chr7_+_11737293 0.12 ENSRNOT00000046059
leucine rich repeat and Ig domain containing 3
chr4_-_160662974 0.12 ENSRNOT00000089199
tetraspanin 9
chr8_+_57886168 0.11 ENSRNOT00000039336
exophilin 5
chr20_+_6351458 0.11 ENSRNOT00000091731
cyclin-dependent kinase inhibitor 1A
chr15_-_28406046 0.11 ENSRNOT00000015418
zinc finger protein 219
chr12_+_47551935 0.11 ENSRNOT00000056932
RGD1560398
chr9_-_93735636 0.11 ENSRNOT00000025582
natriuretic peptide C
chr12_-_16934706 0.11 ENSRNOT00000001720
MAF bZIP transcription factor K
chrX_-_156155014 0.11 ENSRNOT00000088637
L antigen family member 3-like
chr1_-_142197182 0.10 ENSRNOT00000015521
furin (paired basic amino acid cleaving enzyme)
chr16_-_59366824 0.10 ENSRNOT00000015062
similar to 6430573F11Rik protein
chr4_-_82160240 0.10 ENSRNOT00000038775
ENSRNOT00000058985
homeo box A4
chr19_-_43596801 0.10 ENSRNOT00000025625
fatty acid 2-hydroxylase
chr6_-_102196138 0.10 ENSRNOT00000014132
transmembrane protein 229B
chr7_-_101140308 0.10 ENSRNOT00000006279
family with sequence similarity 84, member B
chr10_+_47281786 0.10 ENSRNOT00000089123
potassium voltage-gated channel subfamily J member 12
chr15_-_30147793 0.10 ENSRNOT00000060399

chr20_-_12352377 0.10 ENSRNOT00000044212
solute carrier family 19 member 1
chr8_+_73593310 0.10 ENSRNOT00000012048
C2 calcium-dependent domain containing 4B
chr1_-_89539210 0.10 ENSRNOT00000077462
ENSRNOT00000028644
hepsin
chr1_+_105284753 0.09 ENSRNOT00000041950
solute carrier family 6 member 5
chr20_-_13706205 0.09 ENSRNOT00000038623
derlin 3
chr6_-_125027553 0.09 ENSRNOT00000005908
coiled-coil domain containing 88C
chr8_+_130749838 0.09 ENSRNOT00000079273
SNF related kinase
chr14_+_16491573 0.09 ENSRNOT00000002995
sosondowah ankyrin repeat domain family member B
chr7_+_144647587 0.09 ENSRNOT00000022398
homeo box C4
chr8_-_108109801 0.09 ENSRNOT00000034277
SRY box 14
chr8_-_115167486 0.09 ENSRNOT00000033018
G protein-coupled receptor 62
chr3_+_2877293 0.09 ENSRNOT00000061855
lipocalin 5
chr15_+_37806836 0.09 ENSRNOT00000076285
interleukin 17D
chr9_+_40972089 0.09 ENSRNOT00000067928
protein tyrosine phosphatase, non-receptor type 18
chr12_+_52637000 0.08 ENSRNOT00000063905
GTP binding protein 6 (putative)
chr6_+_28382962 0.08 ENSRNOT00000016976
proopiomelanocortin
chr15_-_80713153 0.08 ENSRNOT00000063800
kelch-like family member 1
chr5_+_151776004 0.08 ENSRNOT00000009683
nuclear receptor subfamily 0, group B, member 2
chr5_-_152987211 0.08 ENSRNOT00000000163
low density lipoprotein receptor adaptor protein 1
chr5_+_139963002 0.08 ENSRNOT00000048506
collagen type IX alpha 2 chain
chr1_+_87224677 0.08 ENSRNOT00000028070
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr18_+_76770012 0.08 ENSRNOT00000089389
PQ loop repeat containing 1
chr14_+_87312203 0.08 ENSRNOT00000088032
adenylate cyclase 1
chr1_-_124803363 0.08 ENSRNOT00000066380
Kruppel-like factor 13
chr13_-_44345735 0.08 ENSRNOT00000005006
transmembrane protein 163
chr3_+_161121697 0.08 ENSRNOT00000036020
WAP four-disulfide core domain 10A
chr5_-_12541019 0.08 ENSRNOT00000091649
suppression of tumorigenicity 18
chr6_-_109004598 0.08 ENSRNOT00000007790
placental growth factor
chr17_-_27112820 0.08 ENSRNOT00000018359
bone morphogenetic protein 6
chr15_-_33527031 0.08 ENSRNOT00000019979
homeobox and leucine zipper encoding
chr7_+_140742418 0.08 ENSRNOT00000089211
peripherin
chr16_+_20672374 0.07 ENSRNOT00000063780
similar to RIKEN cDNA 2810428I15
chr1_-_165680176 0.07 ENSRNOT00000025245
ENSRNOT00000082697
pleckstrin homology domain containing B1
chr10_+_48240330 0.07 ENSRNOT00000057798
sperm antigen with calponin homology and coiled-coil domains 1
chr7_-_130350570 0.07 ENSRNOT00000055805
outer dense fiber of sperm tails 3B
chr4_-_123494742 0.07 ENSRNOT00000073268
solute carrier family 41, member 3
chr9_-_9985358 0.07 ENSRNOT00000080856
crumbs 3, cell polarity complex component
chr10_-_88307132 0.07 ENSRNOT00000040845
junction plakoglobin
chr15_+_41069507 0.07 ENSRNOT00000018533
C1q and tumor necrosis factor related protein 9
chr1_+_211423022 0.07 ENSRNOT00000029587
dihydropyrimidinase-like 4
chr1_+_217173199 0.07 ENSRNOT00000075078
SH3 and multiple ankyrin repeat domains 2
chr6_-_125723944 0.07 ENSRNOT00000007004
fibulin 5
chr9_-_46401911 0.07 ENSRNOT00000046557
cellular repressor of E1A-stimulated genes 2
chr3_+_171037957 0.07 ENSRNOT00000008764
RNA binding motif protein 38
chr4_+_180123905 0.07 ENSRNOT00000083173
Ras association domain family member 8
chr14_+_83724933 0.07 ENSRNOT00000029848
phospholipase A2, group III
chr1_+_100199057 0.07 ENSRNOT00000025831
kallikrein 1
chr1_-_89399039 0.07 ENSRNOT00000028585
ENSRNOT00000044678
lipolysis stimulated lipoprotein receptor
chr10_-_105116916 0.07 ENSRNOT00000012373
envoplakin
chr1_-_89068348 0.07 ENSRNOT00000033621
uroplakin 1A
chr5_+_169475270 0.07 ENSRNOT00000014625
isoprenylcysteine carboxyl methyltransferase
chr15_+_30413488 0.06 ENSRNOT00000071781

chr1_+_214328071 0.06 ENSRNOT00000024725
EPS8-like 2
chr8_-_23390773 0.06 ENSRNOT00000019601
ENSRNOT00000071846
anillin, actin binding protein
chr7_-_12221330 0.06 ENSRNOT00000042204
polo-like kinase 5
chr1_+_152072665 0.06 ENSRNOT00000022538
RAB38, member RAS oncogene family
chr10_-_82887497 0.06 ENSRNOT00000005644
integrin subunit alpha 3
chr14_-_85191557 0.06 ENSRNOT00000011604
neurofilament heavy
chr12_-_44279002 0.06 ENSRNOT00000064900
F-box protein 21
chr12_-_11785493 0.06 ENSRNOT00000039687
zinc finger protein 498
chr8_+_5967463 0.06 ENSRNOT00000086251
transmembrane protein 123
chr10_+_66099531 0.06 ENSRNOT00000056192
LYR motif containing 9
chr17_-_72046381 0.06 ENSRNOT00000073919

chr12_+_52670898 0.06 ENSRNOT00000056632
putative GTP-binding protein 6-like
chr19_-_25288335 0.06 ENSRNOT00000050214
nanos C2HC-type zinc finger 3
chr1_+_24900858 0.06 ENSRNOT00000075616
similar to spermatogenesis associated glutamate (E)-rich protein 4d
chr5_-_137372524 0.06 ENSRNOT00000009061
transmembrane protein 125
chr20_+_13778178 0.06 ENSRNOT00000058314
glutathione S-transferase, theta 4
chr5_-_134978125 0.06 ENSRNOT00000018004
RAD54 like (S. cerevisiae)
chr6_-_125723732 0.06 ENSRNOT00000084815
fibulin 5
chr19_+_16417817 0.06 ENSRNOT00000015272
iroquois homeobox 5
chr3_-_11417546 0.06 ENSRNOT00000018776
lipocalin 2
chr14_+_80403001 0.06 ENSRNOT00000012109
carboxypeptidase Z
chr5_-_12563429 0.06 ENSRNOT00000059625
suppression of tumorigenicity 18
chr1_+_46779860 0.06 ENSRNOT00000075268
sorting nexin 9
chr5_-_160620334 0.06 ENSRNOT00000019171
transmembrane protein 51
chr10_-_108691367 0.06 ENSRNOT00000005067
neuronal pentraxin 1
chr7_-_11003785 0.06 ENSRNOT00000061279
transducin-like enhancer of split 2
chr10_-_63952726 0.06 ENSRNOT00000090461
double C2 domain beta
chr19_+_25123724 0.06 ENSRNOT00000007407
hypothetical protein LOC686013
chrX_+_71272042 0.06 ENSRNOT00000076034
ENSRNOT00000076816
gap junction protein, beta 1
chr3_+_164424515 0.06 ENSRNOT00000083876
CCAAT/enhancer binding protein beta
chr8_-_130429132 0.06 ENSRNOT00000026261
hedgehog acyltransferase-like
chr9_-_98551410 0.06 ENSRNOT00000066346
ENSRNOT00000086678
hes family bHLH transcription factor 6
chr20_-_12351813 0.06 ENSRNOT00000065236
solute carrier family 19 member 1
chr10_+_40247436 0.06 ENSRNOT00000079830
glutathione peroxidase 3
chr10_-_85938085 0.06 ENSRNOT00000043561
plexin domain containing 1
chr6_-_28994519 0.06 ENSRNOT00000006668
UBX domain protein 2A
chr1_+_79727597 0.05 ENSRNOT00000034790

chr5_-_127273656 0.05 ENSRNOT00000057341
DMRT-like family B with proline-rich C-terminal, 1
chr8_+_116771982 0.05 ENSRNOT00000083240

chr19_+_27835890 0.05 ENSRNOT00000042150
disks large homolog 5-like
chr15_+_37790141 0.05 ENSRNOT00000076392
ENSRNOT00000091953
interleukin 17D
chr8_+_50559126 0.05 ENSRNOT00000024918
apolipoprotein A5
chr20_+_4823662 0.05 ENSRNOT00000090028
NFKB inhibitor like 1
chr10_+_36099263 0.05 ENSRNOT00000083568
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr10_-_38838272 0.05 ENSRNOT00000089495
sosondowah ankyrin repeat domain family member A
chr11_+_71872830 0.05 ENSRNOT00000050364
negative regulator of reactive oxygen species
chr10_-_91291774 0.05 ENSRNOT00000004356
rCG33642-like
chrX_-_123662350 0.05 ENSRNOT00000092624
septin 6
chr9_+_10339075 0.05 ENSRNOT00000073402
vimentin-type intermediate filament associated coiled-coil protein
chr4_+_87026530 0.05 ENSRNOT00000018425
AVL9 cell migration associated
chr1_-_88558387 0.05 ENSRNOT00000074174

chr19_+_209926 0.05 ENSRNOT00000071393
uncharacterized LOC108348293
chr12_-_23841049 0.05 ENSRNOT00000031555
heat shock protein family B (small) member 1
chr8_-_116349896 0.05 ENSRNOT00000087306
leucine-rich single-pass membrane protein 2
chr13_-_51183269 0.05 ENSRNOT00000039540
PTPRF interacting protein alpha 4
chr7_+_141370491 0.05 ENSRNOT00000087662
glycerol-3-phosphate dehydrogenase 1
chr20_-_3819200 0.05 ENSRNOT00000000542
ENSRNOT00000081486
hydroxysteroid (17-beta) dehydrogenase 8
chr7_-_11018160 0.05 ENSRNOT00000092061
amino-terminal enhancer of split
chr6_+_108285822 0.05 ENSRNOT00000015889
visual system homeobox 2
chr5_+_137371825 0.05 ENSRNOT00000072816
transmembrane protein 125
chr2_+_225827504 0.05 ENSRNOT00000018343
glutamate cysteine ligase, modifier subunit
chr4_-_30556814 0.05 ENSRNOT00000012760
pyruvate dehydrogenase kinase 4
chr1_-_277768368 0.05 ENSRNOT00000023113
actin filament associated protein 1-like 2
chr1_+_221792221 0.05 ENSRNOT00000054828
neurexin 2
chr1_+_214440503 0.05 ENSRNOT00000025964
calcium release activated channel regulator 2B
chr1_-_222118459 0.05 ENSRNOT00000067217
coiled-coil domain containing 88B
chr1_-_87221826 0.05 ENSRNOT00000046611
ENSRNOT00000028006
serine peptidase inhibitor, Kunitz type, 2
chr1_-_255815733 0.05 ENSRNOT00000047387
cytoplasmic polyadenylation element binding protein 3
chr5_+_169452493 0.05 ENSRNOT00000014444
G protein-coupled receptor 153
chr1_-_242765807 0.05 ENSRNOT00000020763
phosphoglucomutase 5
chr1_-_216156409 0.05 ENSRNOT00000027688
achaete-scute family bHLH transcription factor 2
chr7_-_98960736 0.05 ENSRNOT00000011984
ENSRNOT00000080155
MTSS1, I-BAR domain containing
chr6_+_110410141 0.05 ENSRNOT00000013867
estrogen-related receptor beta
chr4_-_31730386 0.05 ENSRNOT00000013817
solute carrier family 25 member 13
chr3_+_11593655 0.05 ENSRNOT00000074122
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr1_-_72366455 0.05 ENSRNOT00000031786
zinc finger protein 865-like
chr12_+_41385241 0.05 ENSRNOT00000074974
deltex E3 ubiquitin ligase 1
chr12_+_18074033 0.05 ENSRNOT00000001727
integrator complex subunit 1-like
chr1_-_165891627 0.05 ENSRNOT00000038408
RELT tumor necrosis factor receptor
chr19_-_26053762 0.05 ENSRNOT00000004646
microtubule associated serine/threonine kinase 1
chr20_-_3386048 0.05 ENSRNOT00000089550
ENSRNOT00000065025
DEAH-box helicase 16
chr18_+_38847632 0.05 ENSRNOT00000014916
ELMO domain-containing protein 2-like
chr15_+_24153602 0.05 ENSRNOT00000014216
galectin 3
chr4_+_156752082 0.05 ENSRNOT00000084588
ENSRNOT00000068407
CD163 molecule
chr11_+_47200029 0.05 ENSRNOT00000079598
neurexophilin and PC-esterase domain family, member 3
chr4_+_155313671 0.04 ENSRNOT00000020812
microfibrillar associated protein 5
chr5_+_103479767 0.04 ENSRNOT00000008999
SH3 domain-containing GRB2-like 2
chr8_-_22974321 0.04 ENSRNOT00000017369
erythropoietin receptor
chr4_-_183293999 0.04 ENSRNOT00000079695
importin 8
chr12_-_40227297 0.04 ENSRNOT00000030600
family with sequence similarity 109, member A
chr5_+_28480023 0.04 ENSRNOT00000075067
ENSRNOT00000093754
uncharacterized LOC100912373
chr4_+_7355574 0.04 ENSRNOT00000013800
potassium voltage-gated channel subfamily H member 2
chr17_+_15845931 0.04 ENSRNOT00000092083
caspase recruitment domain family, member 19

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf4_Mesp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.3 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.2 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.1 GO:0032900 negative regulation of neurotrophin production(GO:0032900)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:0034769 basement membrane disassembly(GO:0034769)
0.0 0.1 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:1990792 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
0.0 0.2 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.1 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0032349 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0035711 granuloma formation(GO:0002432) T-helper 1 cell activation(GO:0035711)
0.0 0.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.0 GO:0071663 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.0 0.0 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.0 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:1904373 response to kainic acid(GO:1904373)
0.0 0.0 GO:2000019 negative regulation of male gonad development(GO:2000019)
0.0 0.0 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.0 0.0 GO:0031439 positive regulation of mRNA cleavage(GO:0031439) positive regulation of endoribonuclease activity(GO:1902380) positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904722)
0.0 0.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.0 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:1903059 regulation of protein lipidation(GO:1903059)
0.0 0.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.1 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.0 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.0 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.0 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0032423 regulation of mismatch repair(GO:0032423)
0.0 0.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.0 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.0 GO:0021550 medulla oblongata development(GO:0021550)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.0 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0032173 septin collar(GO:0032173)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 0.2 GO:0098603 selenol Se-methyltransferase activity(GO:0098603)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.2 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.0 GO:0031249 denatured protein binding(GO:0031249)
0.0 0.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.0 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.0 GO:0004956 prostaglandin D receptor activity(GO:0004956)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions