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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Tbx1_Eomes

Z-value: 0.34

Motif logo

Transcription factors associated with Tbx1_Eomes

Gene Symbol Gene ID Gene Info
ENSRNOG00000001892 T-box 1
ENSRNOG00000042140 eomesodermin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Eomesrn6_v1_chr8_+_127144903_1271449030.894.6e-02Click!
Tbx1rn6_v1_chr11_+_86552022_865520220.761.3e-01Click!

Activity profile of Tbx1_Eomes motif

Sorted Z-values of Tbx1_Eomes motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_227047290 0.12 ENSRNOT00000037226
membrane spanning 4-domains A15
chr6_+_28323647 0.10 ENSRNOT00000089093
DNA methyltransferase 3 alpha
chr1_-_124803363 0.10 ENSRNOT00000066380
Kruppel-like factor 13
chr9_-_63637677 0.09 ENSRNOT00000049259
SATB homeobox 2
chr18_+_53609214 0.09 ENSRNOT00000077443
solute carrier family 27 member 6
chr12_+_52359310 0.08 ENSRNOT00000071857
ENSRNOT00000065893
fibrosin-like 1
chr16_+_46731403 0.08 ENSRNOT00000017624
teneurin transmembrane protein 3
chr4_-_180234804 0.08 ENSRNOT00000070957
basic helix-loop-helix family, member e41
chr10_-_88754829 0.07 ENSRNOT00000026354
signal transducer and activator of transcription 5B
chr3_+_161433410 0.07 ENSRNOT00000024657
solute carrier family 12 member 5
chr9_-_15700235 0.07 ENSRNOT00000088713
ENSRNOT00000035907
transcriptional regulating factor 1
chr10_-_88645364 0.07 ENSRNOT00000030344
RAB5C, member RAS oncogene family
chr19_-_25288335 0.07 ENSRNOT00000050214
nanos C2HC-type zinc finger 3
chr5_+_136683592 0.06 ENSRNOT00000085527
solute carrier family 6 member 9
chr3_+_131351587 0.06 ENSRNOT00000010835
BTB domain containing 3
chr2_+_207262934 0.06 ENSRNOT00000016833
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr8_-_45215974 0.06 ENSRNOT00000010792
cytotoxic and regulatory T cell molecule
chr5_+_143500441 0.05 ENSRNOT00000045513
glutamate ionotropic receptor kainate type subunit 3
chr20_+_6351458 0.05 ENSRNOT00000091731
cyclin-dependent kinase inhibitor 1A
chr6_-_44363915 0.05 ENSRNOT00000085925
inhibitor of DNA binding 2, HLH protein
chr17_-_14091766 0.04 ENSRNOT00000075373

chr1_-_20155960 0.04 ENSRNOT00000061389
sterile alpha motif domain containing 3
chr1_+_187149453 0.04 ENSRNOT00000082738
xylosyltransferase 1
chr8_-_78233430 0.04 ENSRNOT00000083220
cingulin-like 1
chr2_-_177924970 0.04 ENSRNOT00000029340
Rap guanine nucleotide exchange factor 2
chr4_+_146455332 0.04 ENSRNOT00000009775
histamine receptor H 1
chr1_+_238222521 0.04 ENSRNOT00000024000
aldehyde dehydrogenase 1 family, member A1
chr15_+_8739589 0.04 ENSRNOT00000071751
nuclear receptor subfamily 1, group D, member 2
chr5_+_63781801 0.03 ENSRNOT00000008302
nuclear receptor subfamily 4, group A, member 3
chr5_-_12563429 0.03 ENSRNOT00000059625
suppression of tumorigenicity 18
chr1_+_79982639 0.03 ENSRNOT00000071916
dystrophia myotonica, WD repeat containing
chr18_-_28871849 0.03 ENSRNOT00000025902
neuregulin 2
chr7_+_41475163 0.03 ENSRNOT00000037844
dual specificity phosphatase 6
chr3_+_160231914 0.03 ENSRNOT00000014411
potassium two pore domain channel subfamily K member 15
chr2_+_263212051 0.03 ENSRNOT00000089396
neuronal growth regulator 1
chr17_-_80320681 0.03 ENSRNOT00000023637
complement C1q like 3
chr5_-_150704117 0.03 ENSRNOT00000067455
sestrin 2
chr6_+_101532518 0.03 ENSRNOT00000075054
gephyrin
chr8_+_32188617 0.03 ENSRNOT00000081145
zinc finger and BTB domain containing 44
chr5_+_58393603 0.02 ENSRNOT00000080082
DnaJ heat shock protein family (Hsp40) member B5
chr11_+_47061354 0.02 ENSRNOT00000039997
PEST proteolytic signal containing nuclear protein
chr14_+_12218553 0.02 ENSRNOT00000003237
protein kinase, cGMP-dependent, type II
chr2_-_62634785 0.02 ENSRNOT00000017937
PDZ domain containing 2
chr7_-_27240528 0.02 ENSRNOT00000029435
ENSRNOT00000079731
heat shock protein 90 beta family member 1
chr20_+_2501252 0.02 ENSRNOT00000079307
ENSRNOT00000084559
tripartite motif-containing 39
chr9_+_3896337 0.02 ENSRNOT00000079166
protein tyrosine phosphatase type IVA 1
chr11_-_4397361 0.02 ENSRNOT00000046370
cell adhesion molecule 2
chr11_+_61662270 0.02 ENSRNOT00000079521
zinc finger, DHHC-type containing 23
chr1_-_264975132 0.02 ENSRNOT00000021748
ladybird homeobox 1
chr4_-_100783016 0.02 ENSRNOT00000020671
potassium channel modulatory factor 1
chrX_+_70563570 0.02 ENSRNOT00000003772
glycerophosphodiester phosphodiesterase domain containing 2
chr5_-_79874671 0.02 ENSRNOT00000084563
tenascin C
chr18_+_46148849 0.02 ENSRNOT00000026724
proline rich 16
chr11_+_80255790 0.02 ENSRNOT00000002522
B-cell CLL/lymphoma 6
chr1_-_72468738 0.02 ENSRNOT00000029136
zinc finger protein 628
chr2_+_74360622 0.02 ENSRNOT00000014013
cadherin 18
chrM_+_7758 0.02 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr8_+_117068582 0.01 ENSRNOT00000073559
aminomethyltransferase
chr8_-_6034142 0.01 ENSRNOT00000014560
baculoviral IAP repeat-containing 2
chr2_-_104133985 0.01 ENSRNOT00000088167
ENSRNOT00000067725
phosphodiesterase 7A
chr2_+_140836006 0.01 ENSRNOT00000074141
dual specificity phosphatase 14-like 1
chr3_-_43119159 0.01 ENSRNOT00000041394
nuclear receptor subfamily 4, group A, member 2
chr19_-_37907714 0.01 ENSRNOT00000026361
chymotrypsin-like
chr6_-_124429701 0.01 ENSRNOT00000037902
ENSRNOT00000080950
tetratricopeptide repeat domain 7B
chr15_-_33250546 0.01 ENSRNOT00000017857
similar to RIKEN cDNA 4931414P19
chr3_+_5624506 0.01 ENSRNOT00000036995
ADAMTS-like 2
chr18_+_72571327 0.01 ENSRNOT00000089468
SMAD family member 2
chr20_+_2058197 0.01 ENSRNOT00000077774
ENSRNOT00000040634
RT1 class I, locus M6, gene 1
chr13_-_25262469 0.01 ENSRNOT00000019921
ring finger protein 152
chr4_+_58053041 0.01 ENSRNOT00000072698
mesoderm specific transcript
chr1_+_224824799 0.01 ENSRNOT00000024757
solute carrier family 22 member 6
chr1_-_226353611 0.01 ENSRNOT00000037624
diacylglycerol lipase, alpha
chr11_+_43143882 0.01 ENSRNOT00000041445
olfactory receptor 1528
chr10_+_85608544 0.01 ENSRNOT00000092122
MLLT6, PHD finger domain containing
chr14_+_42714315 0.01 ENSRNOT00000084095
ENSRNOT00000091449
paired-like homeobox 2b
chr13_-_90467235 0.01 ENSRNOT00000081534
ENSRNOT00000008150
nicastrin
chr5_+_156587093 0.01 ENSRNOT00000019696
heterochromatin protein 1, binding protein 3
chr8_+_36410683 0.00 ENSRNOT00000015177
SRP receptor alpha subunit
chr4_+_71675383 0.00 ENSRNOT00000051265
chloride voltage-gated channel 1
chr16_+_70068378 0.00 ENSRNOT00000073254
similar to DNA segment, Chr 19, Brigham & Womens Genetics 1357 expressed
chr19_+_39063998 0.00 ENSRNOT00000081116
hyaluronan synthase 3
chr13_-_79801112 0.00 ENSRNOT00000087323
ENSRNOT00000036483
SUN domain containing ossification factor
chr18_-_40134504 0.00 ENSRNOT00000022294
tripartite motif-containing 36
chr10_-_83104173 0.00 ENSRNOT00000031252
lysine acetyltransferase 7
chr1_-_214423881 0.00 ENSRNOT00000025290
p53-induced death domain protein 1
chr8_+_28352772 0.00 ENSRNOT00000012391
immunoglobulin superfamily, member 9B
chrX_+_16946207 0.00 ENSRNOT00000003981
similar to cysteine-rich protein 2
chr4_-_82133605 0.00 ENSRNOT00000008023
homeobox A2
chr8_-_36410612 0.00 ENSRNOT00000091308
FAD-dependent oxidoreductase domain containing 1
chr18_-_29611212 0.00 ENSRNOT00000022685
DND microRNA-mediated repression inhibitor 1
chr10_-_56511583 0.00 ENSRNOT00000021402
similar to RIKEN cDNA 2810408A11
chr2_+_198755262 0.00 ENSRNOT00000028807
RNA binding motif protein 8A

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx1_Eomes

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.0 0.1 GO:0090116 hypermethylation of CpG island(GO:0044027) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.0 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.1 GO:0032763 regulation of mast cell cytokine production(GO:0032763)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0070557 PCNA-p21 complex(GO:0070557)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.0 GO:0004969 histamine receptor activity(GO:0004969)