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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Tbx15
Z-value: 0.54
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Transcription factors associated with Tbx15
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tbx15 | rn6_v1_chr2_+_201289357_201289357 | 0.49 | 4.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_45215974 Show fit | 0.37 |
ENSRNOT00000010792
|
cytotoxic and regulatory T cell molecule |
|
| chr15_-_30147793 Show fit | 0.33 |
ENSRNOT00000060399
|
|
|
| chr5_-_12563429 Show fit | 0.29 |
ENSRNOT00000059625
|
suppression of tumorigenicity 18 |
|
| chr18_+_53609214 Show fit | 0.25 |
ENSRNOT00000077443
|
solute carrier family 27 member 6 |
|
| chr3_+_161433410 Show fit | 0.24 |
ENSRNOT00000024657
|
solute carrier family 12 member 5 |
|
| chr13_+_71107465 Show fit | 0.24 |
ENSRNOT00000003239
|
regulator of G-protein signaling 8 |
|
| chr1_-_264975132 Show fit | 0.22 |
ENSRNOT00000021748
|
ladybird homeobox 1 |
|
| chr15_+_8739589 Show fit | 0.21 |
ENSRNOT00000071751
|
nuclear receptor subfamily 1, group D, member 2 |
|
| chr4_+_140247313 Show fit | 0.21 |
ENSRNOT00000040255
ENSRNOT00000064025 ENSRNOT00000041130 ENSRNOT00000043646 |
inositol 1,4,5-trisphosphate receptor, type 1 |
|
| chr3_+_131351587 Show fit | 0.21 |
ENSRNOT00000010835
|
BTB domain containing 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Tbx15
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0002857 | positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) |
| 0.1 | 0.3 | GO:0046544 | development of secondary male sexual characteristics(GO:0046544) |
| 0.0 | 0.3 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.1 | 0.2 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
| 0.0 | 0.2 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.0 | 0.2 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.0 | 0.2 | GO:0048664 | neuron fate determination(GO:0048664) |
| 0.0 | 0.2 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.0 | 0.2 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.0 | 0.2 | GO:0071420 | cellular response to histamine(GO:0071420) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.0 | 0.1 | GO:0061673 | mitotic spindle astral microtubule(GO:0061673) |
| 0.0 | 0.1 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.1 | GO:0033648 | host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) |
| 0.0 | 0.0 | GO:0090534 | calcium ion-transporting ATPase complex(GO:0090534) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 0.2 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.0 | 0.2 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.0 | 0.2 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.2 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.0 | 0.2 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.2 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.0 | 0.1 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 0.0 | 0.1 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) glycoprotein transporter activity(GO:0034437) |
| 0.0 | 0.1 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | PID IL5 PATHWAY | IL5-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 0.2 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.1 | REACTOME AMYLOIDS | Genes involved in Amyloids |