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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Tal1

Z-value: 0.31

Motif logo

Transcription factors associated with Tal1

Gene Symbol Gene ID Gene Info
ENSRNOG00000025051 TAL bHLH transcription factor 1, erythroid differentiation factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tal1rn6_v1_chr5_+_133864798_1338647980.237.1e-01Click!

Activity profile of Tal1 motif

Sorted Z-values of Tal1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_23187341 0.19 ENSRNOT00000000180
5'-aminolevulinate synthase 2
chr10_-_15590220 0.18 ENSRNOT00000048977
hemoglobin alpha, adult chain 2
chr5_+_153197459 0.17 ENSRNOT00000023187
Rh blood group, D antigen
chr20_+_4593389 0.12 ENSRNOT00000001174
solute carrier family 44, member 4
chr10_-_15603649 0.12 ENSRNOT00000051483
hemoglobin alpha, adult chain 2
chr1_+_279798187 0.11 ENSRNOT00000024065
pancreatic lipase
chr1_+_175445088 0.11 ENSRNOT00000036718
adrenomedullin
chr7_-_145174771 0.10 ENSRNOT00000055270
glycosylation dependent cell adhesion molecule 1
chr17_-_22143324 0.09 ENSRNOT00000019361
endothelin 1
chr7_+_121841855 0.09 ENSRNOT00000024673
GRB2-related adaptor protein 2
chr1_-_164205222 0.09 ENSRNOT00000035774
monoacylglycerol O-acyltransferase 2
chr7_-_115981731 0.08 ENSRNOT00000036549
similar to secreted Ly6/uPAR related protein 2
chr7_+_138707426 0.07 ENSRNOT00000037874
PC-esterase domain containing 1B
chrX_-_121731543 0.07 ENSRNOT00000018788
kelch-like family member 13
chr3_-_123702732 0.07 ENSRNOT00000028859
similar to RIKEN cDNA 1700037H04
chr10_-_16788126 0.07 ENSRNOT00000077386
ATPase H+ transporting V0 subunit e1
chr16_-_75648538 0.06 ENSRNOT00000048414
defensin beta 14
chr20_-_5806097 0.06 ENSRNOT00000000611
colipase
chr11_-_81344488 0.06 ENSRNOT00000002492
adiponectin, C1Q and collagen domain containing
chr4_+_57855416 0.06 ENSRNOT00000029608
carboxypeptidase A2
chr16_-_45929 0.06 ENSRNOT00000043153

chr13_-_80745347 0.06 ENSRNOT00000041908
flavin containing monooxygenase 1
chr14_-_84189266 0.05 ENSRNOT00000005934
transcobalamin 2
chr2_+_208541361 0.05 ENSRNOT00000021288
transmembrane and immunoglobulin domain containing 3
chr6_-_137084739 0.05 ENSRNOT00000060943
transmembrane protein 179
chr4_-_166617143 0.05 ENSRNOT00000038077

chr15_-_45524582 0.05 ENSRNOT00000081912
guanylate cyclase 1 soluble subunit beta 2
chr14_-_18704059 0.05 ENSRNOT00000081455
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr1_+_73040901 0.05 ENSRNOT00000071927
glycoprotein 6 (platelet)
chr1_-_37990007 0.05 ENSRNOT00000081054

chr7_-_71269869 0.05 ENSRNOT00000037030
ubiquinol-cytochrome c reductase binding protein
chr8_-_119326938 0.05 ENSRNOT00000044467
C-C motif chemokine receptor like 2
chr5_+_126862987 0.05 ENSRNOT00000080701
heat shock protein family B (small), member 11
chr17_-_21677477 0.04 ENSRNOT00000035448
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr9_+_81535483 0.04 ENSRNOT00000077285
actin related protein 2/3 complex, subunit 2
chr8_-_33661049 0.04 ENSRNOT00000068037
Fli-1 proto-oncogene, ETS transcription factor
chr18_-_81682206 0.04 ENSRNOT00000058219
hypothetical protein LOC100359752
chr5_+_133864798 0.04 ENSRNOT00000091977
TAL bHLH transcription factor 1, erythroid differentiation factor
chr10_-_87407634 0.04 ENSRNOT00000016657
keratin 23
chr2_-_123851854 0.04 ENSRNOT00000023327
interleukin 2
chr16_-_21338771 0.04 ENSRNOT00000014265
PBX homeobox 4
chr13_+_83972212 0.04 ENSRNOT00000004394
cellular repressor of E1A-stimulated genes 1
chr10_-_88107232 0.04 ENSRNOT00000019330
ENSRNOT00000076770
keratin 9
chr10_-_15610826 0.04 ENSRNOT00000027851
hemoglobin subunit zeta
chr7_-_33793565 0.04 ENSRNOT00000065354

chr10_-_102227554 0.04 ENSRNOT00000078035

chr14_+_22517774 0.04 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr1_-_98570949 0.04 ENSRNOT00000033648
sialic acid binding Ig-like lectin 5
chr19_+_14835822 0.04 ENSRNOT00000072804
RIKEN cDNA 1700007B14 gene
chr1_+_279896973 0.04 ENSRNOT00000068119
pancreatic lipase related protein 2
chr9_-_23493081 0.04 ENSRNOT00000072144
Rh-associated glycoprotein
chr7_+_60015998 0.04 ENSRNOT00000007309
bestrophin 3
chr6_+_27975849 0.04 ENSRNOT00000060810
dystrobrevin, beta
chr10_-_34961608 0.04 ENSRNOT00000033056
heterogeneous nuclear ribonucleoprotein A/B
chrX_-_63803915 0.04 ENSRNOT00000076938
MAGE family member D1
chr20_-_2191640 0.03 ENSRNOT00000001016
tripartite motif-containing 10
chr2_+_190073815 0.03 ENSRNOT00000015473
S100 calcium binding protein A8
chr5_+_164808323 0.03 ENSRNOT00000011005
natriuretic peptide A
chr17_+_49714294 0.03 ENSRNOT00000018190
RAS like proto-oncogene A
chr20_+_13498926 0.03 ENSRNOT00000070992
ENSRNOT00000045375
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr8_+_22047697 0.03 ENSRNOT00000067741
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr2_-_187909394 0.03 ENSRNOT00000032355
RAB25, member RAS oncogene family
chr1_+_189359853 0.03 ENSRNOT00000055083
acyl-CoA synthetase medium-chain family member 1
chr1_+_100501676 0.03 ENSRNOT00000043724
family with sequence similarity 71, member E1
chr16_-_68968248 0.03 ENSRNOT00000016885
eukaryotic translation initiation factor 4E binding protein 1
chr3_+_103945329 0.03 ENSRNOT00000008364
ER membrane protein complex subunit 7
chr3_+_5519990 0.03 ENSRNOT00000070873
ENSRNOT00000007640
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr2_-_88660449 0.03 ENSRNOT00000051741
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr19_-_53477420 0.03 ENSRNOT00000071344
hypothetical protein LOC687560
chr7_-_8060373 0.03 ENSRNOT00000071699
olfactory receptor 798
chr5_+_57845819 0.03 ENSRNOT00000017712
nudix hydrolase 2
chr3_+_119561290 0.03 ENSRNOT00000015843
biliverdin reductase A
chr4_-_119148358 0.03 ENSRNOT00000012218
gastrokine 1
chr1_-_213635546 0.03 ENSRNOT00000018861
sirtuin 3
chr10_-_68926264 0.03 ENSRNOT00000008661
prohibitin, pseudogene 1
chr2_-_193335002 0.03 ENSRNOT00000012691
late cornified envelope 1M
chr1_+_220416018 0.03 ENSRNOT00000027233
beta-1,4-glucuronyltransferase 1
chr12_-_38116919 0.03 ENSRNOT00000001467
density regulated reinitiation and release factor
chr8_+_64088913 0.03 ENSRNOT00000013022
ADP-dependent glucokinase
chr7_-_143738237 0.03 ENSRNOT00000055320
SPRY domain containing 3
chr16_-_18645941 0.03 ENSRNOT00000079241
DPY30 domain containing 2
chr5_+_48303366 0.03 ENSRNOT00000009973
gamma-aminobutyric acid type A receptor rho 2 subunit
chr1_+_142883040 0.03 ENSRNOT00000015898
alpha-kinase 3
chr8_-_63291966 0.03 ENSRNOT00000077762

chr16_-_39970532 0.03 ENSRNOT00000071331
spermatogenesis associated 4
chr4_+_7662019 0.03 ENSRNOT00000014023
family with sequence similarity 126, member A
chr14_-_110883784 0.03 ENSRNOT00000086299
ENSRNOT00000068190
vaccinia related kinase 2
chr6_+_58388333 0.03 ENSRNOT00000036337
similar to 40S ribosomal protein S2
chr10_+_105630810 0.03 ENSRNOT00000064904
photoreceptor disc component
chr10_-_89374516 0.03 ENSRNOT00000028084
vesicle amine transport 1
chr8_-_17525906 0.03 ENSRNOT00000007855
N-acetylated alpha-linked acidic dipeptidase 2
chr18_-_37096132 0.02 ENSRNOT00000041188
protein phosphatase 2, regulatory subunit B, beta
chr5_+_144701949 0.02 ENSRNOT00000015618
proteasome subunit beta 2
chrX_-_16537888 0.02 ENSRNOT00000060247
diacylglycerol kinase kappa
chr10_+_10967658 0.02 ENSRNOT00000004999
cell death-inducing p53 target 1
chr10_+_83201311 0.02 ENSRNOT00000006179
solute carrier family 35, member B1
chr7_-_121000272 0.02 ENSRNOT00000020941
dynein, axonemal, light chain 4
chr4_-_145300177 0.02 ENSRNOT00000029728
calcium/calmodulin-dependent protein kinase I
chr8_-_66863476 0.02 ENSRNOT00000018820
ribosomal protein lateral stalk subunit P1
chr8_-_48672732 0.02 ENSRNOT00000079275
hydroxymethylbilane synthase
chr9_-_113358526 0.02 ENSRNOT00000065073
thioredoxin domain containing 2
chr19_-_42920344 0.02 ENSRNOT00000019408
ENSRNOT00000068594
zinc finger homeobox 3
chr1_+_213676954 0.02 ENSRNOT00000050551
NLR family, pyrin domain containing 6
chr10_+_53740841 0.02 ENSRNOT00000004295
myosin heavy chain 2
chr16_+_51748970 0.02 ENSRNOT00000059182
a disintegrin and metallopeptidase domain 26A
chr18_+_35136132 0.02 ENSRNOT00000078731
serine peptidase inhibitor, Kazal type 5
chr4_+_29535852 0.02 ENSRNOT00000087619
collagen, type I, alpha 2
chr15_+_59678165 0.02 ENSRNOT00000074868
ecto-NOX disulfide-thiol exchanger 1
chr7_-_116504853 0.02 ENSRNOT00000056557
similar to Ly6-C antigen gene
chr1_+_88620317 0.02 ENSRNOT00000075116
cytochrome c oxidase subunit 7A1
chr4_-_165195489 0.02 ENSRNOT00000079429
killer cell lectin-like receptor, subfamily A, member 5
chr1_-_100501437 0.02 ENSRNOT00000026445
ER membrane protein complex subunit 10
chr19_-_49623758 0.02 ENSRNOT00000071130
polycystic kidney disease 1-like 2
chr10_-_90415070 0.02 ENSRNOT00000055179
integrin subunit alpha 2b
chr2_+_85377318 0.02 ENSRNOT00000016506
ENSRNOT00000085094
semaphorin 5A
chr1_+_81499821 0.02 ENSRNOT00000027100
Ly6/Plaur domain containing 3
chr17_+_76008807 0.02 ENSRNOT00000070895
enoyl CoA hydratase domain containing 3
chr3_-_161246351 0.02 ENSRNOT00000020348
troponin C2, fast skeletal type
chr16_-_82999827 0.02 ENSRNOT00000041223
testis expressed 29
chr1_-_153752541 0.02 ENSRNOT00000080927
protease, serine, 23
chrX_-_135342996 0.02 ENSRNOT00000084848
ENSRNOT00000008503
apoptosis inducing factor, mitochondria associated 1
chr7_+_120153184 0.02 ENSRNOT00000013538
galectin 1
chr6_+_102477036 0.02 ENSRNOT00000087132
RAD51 paralog B
chr5_-_78324278 0.02 ENSRNOT00000082642
ENSRNOT00000048904
WD repeat domain 31
chr9_-_113357933 0.02 ENSRNOT00000032330
thioredoxin domain containing 2
chr10_+_106785077 0.02 ENSRNOT00000075047
transmembrane channel-like 8
chr2_+_212257225 0.02 ENSRNOT00000077883
vav guanine nucleotide exchange factor 3
chrX_+_13441558 0.02 ENSRNOT00000030170
similar to Ferritin light chain (Ferritin L subunit)
chr13_-_72869396 0.02 ENSRNOT00000093563
similar to 6820428L09 protein
chr4_-_61720956 0.02 ENSRNOT00000012879
aldo-keto reductase family 1 member B
chr5_-_133067245 0.02 ENSRNOT00000033163
selection and upkeep of intraepithelial T cells 10
chr2_+_142717281 0.02 ENSRNOT00000014765
ENSRNOT00000076774
stomatin like 3
chr13_+_51218468 0.02 ENSRNOT00000033636
similar to UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylgluco
chr13_-_51373399 0.02 ENSRNOT00000060656
MGAT4 family, member E
chr10_-_103919605 0.02 ENSRNOT00000004718
HID1 domain containing
chr15_+_33606124 0.02 ENSRNOT00000065210

chr16_+_61926586 0.02 ENSRNOT00000058884

chr3_-_148706972 0.02 ENSRNOT00000036956
testis specific protein, Y-linked 26
chr1_+_213686046 0.02 ENSRNOT00000019808
NACHT, LRR and PYD domains-containing protein 6-like
chr1_+_260289589 0.02 ENSRNOT00000051058
DNA nucleotidylexotransferase
chrX_-_135250519 0.02 ENSRNOT00000044487
E74 like ETS transcription factor 4
chr1_+_198210525 0.02 ENSRNOT00000026755
yippee-like 3
chrX_-_84167717 0.02 ENSRNOT00000006415
premature ovarian failure 1B
chr13_+_76962504 0.02 ENSRNOT00000076581
ring finger and WD repeat domain 2
chr10_-_37055282 0.02 ENSRNOT00000086193
ENSRNOT00000065584
heterogeneous nuclear ribonucleoprotein A/B
chr12_-_24365324 0.02 ENSRNOT00000032250
tripartite motif-containing 50
chr2_+_24668116 0.02 ENSRNOT00000067022
ENSRNOT00000036748
WD repeat domain 41
chr15_+_34446878 0.02 ENSRNOT00000027619
leukotriene B4 receptor 2
chrX_+_124631881 0.02 ENSRNOT00000009329
ATPase Na+/K+ transporting family member beta 4
chr4_+_82776746 0.02 ENSRNOT00000011371
Tax1 binding protein 1
chr12_+_17252093 0.02 ENSRNOT00000047634
zinc finger AN1-type containing 2A
chr3_+_147511406 0.02 ENSRNOT00000082438
solute carrier family 52 member 3
chr16_+_14306804 0.02 ENSRNOT00000017773
leucine-rich repeat, Ig-like and transmembrane domains 1
chr1_-_147077568 0.02 ENSRNOT00000074040
synaptonemal complex protein 3-like
chr1_-_222459952 0.02 ENSRNOT00000028752
OTU deubiquitinase, ubiquitin aldehyde binding 1
chr1_+_86972244 0.02 ENSRNOT00000036907
Ras and Rab interactor-like
chr4_-_165541314 0.02 ENSRNOT00000013833
serine/threonine/tyrosine kinase 1
chr9_+_44025020 0.02 ENSRNOT00000024582
unc-50 inner nuclear membrane RNA binding protein
chr1_+_227640680 0.02 ENSRNOT00000033613
membrane-spanning 4-domains, subfamily A, member 4C
chr1_-_201110928 0.02 ENSRNOT00000027721
NSE4 homolog A, SMC5-SMC6 complex component
chr4_+_56337695 0.02 ENSRNOT00000071926
leptin
chr5_+_173373888 0.02 ENSRNOT00000077602
ubiquitin-conjugating enzyme E2, J2
chr10_+_70417108 0.02 ENSRNOT00000079325
schlafen 4
chr14_-_78469480 0.02 ENSRNOT00000006771
janus kinase and microtubule interacting protein 1
chr4_+_147333056 0.02 ENSRNOT00000012137
peroxisome proliferator-activated receptor gamma
chr4_+_14070553 0.02 ENSRNOT00000077505
CD36 molecule
chr8_-_86286991 0.02 ENSRNOT00000046322
similar to RIKEN cDNA 2900055D03
chr1_+_260732485 0.02 ENSRNOT00000076842
ENSRNOT00000076073
ligand dependent nuclear receptor corepressor
chr7_-_17520780 0.02 ENSRNOT00000029672
similar to NACHT, leucine rich repeat and PYD containing 4A
chr13_+_52645257 0.01 ENSRNOT00000012801
ladinin 1
chr4_+_7661558 0.01 ENSRNOT00000080229
family with sequence similarity 126, member A
chr9_-_44024876 0.01 ENSRNOT00000024366
cytochrome C oxidase assembly factor 5
chr10_+_70411738 0.01 ENSRNOT00000078046
schlafen 4
chr1_-_141893674 0.01 ENSRNOT00000019059
ENSRNOT00000085988
isocitrate dehydrogenase (NADP(+)) 2, mitochondrial
chrX_+_34623405 0.01 ENSRNOT00000041924
NHS actin remodeling regulator
chr15_+_30557388 0.01 ENSRNOT00000072978

chrX_+_69730242 0.01 ENSRNOT00000075980
ENSRNOT00000076425
ectodysplasin-A
chr3_+_147511563 0.01 ENSRNOT00000006828
solute carrier family 52 member 3
chr3_+_56802714 0.01 ENSRNOT00000077551
glutamate-rich 2
chr3_+_114253637 0.01 ENSRNOT00000046843
dual oxidase 1
chr5_+_98387291 0.01 ENSRNOT00000046503
tyrosinase-related protein 1
chr4_-_23718047 0.01 ENSRNOT00000011359
similar to RIKEN cDNA 4921511H03
chr1_+_143583675 0.01 ENSRNOT00000026385
family with sequence similarity 103, member A1
chr3_-_123236535 0.01 ENSRNOT00000028839
solute carrier family 4 member 11
chr10_+_37032043 0.01 ENSRNOT00000037303
ENSRNOT00000091242
5-phosphohydroxy-L-lysine phospho-lyase
chr15_+_57290849 0.01 ENSRNOT00000014909
carboxypeptidase B2
chr10_-_110232843 0.01 ENSRNOT00000054934
Cd7 molecule
chr7_+_125920357 0.01 ENSRNOT00000018365
uroplakin 3A
chr3_-_2453933 0.01 ENSRNOT00000014060
solute carrier family 34 member 3
chr15_-_37410848 0.01 ENSRNOT00000081757
gap junction protein, beta 6
chr1_+_234252757 0.01 ENSRNOT00000091814
RAR-related orphan receptor B
chr18_+_44716226 0.01 ENSRNOT00000086431
TNF alpha induced protein 8
chr1_-_175895510 0.01 ENSRNOT00000064535
eukaryotic translation initiation factor 4, gamma 2
chr13_+_82072497 0.01 ENSRNOT00000063810
ENSRNOT00000085135
kinesin-associated protein 3
chr19_+_10024947 0.01 ENSRNOT00000061392
cilia and flagella associated protein 20
chr20_+_31761405 0.01 ENSRNOT00000000661
neurogenin 3
chr1_+_63263722 0.01 ENSRNOT00000088203
vomeronasal type-1 receptor 4-like
chr14_+_44889287 0.01 ENSRNOT00000091312
ENSRNOT00000032273
transmembrane protein 156
chr1_-_72941869 0.01 ENSRNOT00000032306
EPS8-like 1
chr17_-_84247038 0.01 ENSRNOT00000068553
nebulette

Network of associatons between targets according to the STRING database.

First level regulatory network of Tal1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:1901423 response to benzene(GO:1901423)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0031583 phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.1 GO:0000105 histidine biosynthetic process(GO:0000105)
0.0 0.1 GO:0072249 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532)
0.0 0.0 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.0 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.1 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.0 GO:2000814 positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.0 GO:0032218 riboflavin transport(GO:0032218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0048237 Weibel-Palade body(GO:0033093) rough endoplasmic reticulum lumen(GO:0048237)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0043199 sulfate binding(GO:0043199)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.0 GO:0032217 riboflavin transporter activity(GO:0032217)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins