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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for T

Z-value: 0.33

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Transcription factors associated with T

Gene Symbol Gene ID Gene Info
ENSRNOG00000012229 T brachyury transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Trn6_v1_chr1_-_52894832_528948320.207.4e-01Click!

Activity profile of T motif

Sorted Z-values of T motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_152883210 0.22 ENSRNOT00000056200
coiled-coil domain containing 77
chr4_-_148845267 0.16 ENSRNOT00000037397
transmembrane protein 72
chr1_-_219422268 0.12 ENSRNOT00000025092
carnosine synthase 1
chr8_-_46694613 0.11 ENSRNOT00000084514

chr7_-_130120579 0.10 ENSRNOT00000044376
mitogen-activated protein kinase 12
chr2_-_23289266 0.09 ENSRNOT00000061708
betaine-homocysteine S-methyltransferase 2
chr13_-_25262469 0.09 ENSRNOT00000019921
ring finger protein 152
chr8_+_72405748 0.08 ENSRNOT00000023952
carbonic anhydrase 12
chr9_-_20528879 0.07 ENSRNOT00000085293

chr4_-_59014416 0.07 ENSRNOT00000049811
similar to 60S ribosomal protein L38
chr10_+_55712043 0.06 ENSRNOT00000010141
arachidonate lipoxygenase 3
chr15_+_34552410 0.06 ENSRNOT00000027802
KH and NYN domain containing
chr1_-_214423881 0.06 ENSRNOT00000025290
p53-induced death domain protein 1
chr5_-_62186372 0.06 ENSRNOT00000089789
coronin 2A
chr18_+_38847632 0.06 ENSRNOT00000014916
ELMO domain-containing protein 2-like
chr7_-_47586137 0.05 ENSRNOT00000006086
transmembrane and tetratricopeptide repeat containing 2
chr9_-_89193821 0.05 ENSRNOT00000090881
SPHK1 interactor, AKAP domain containing
chr15_+_10120206 0.05 ENSRNOT00000033048
retinoic acid receptor, beta
chr20_-_27578244 0.05 ENSRNOT00000000708
family with sequence similarity 26, member D
chr18_-_3662654 0.05 ENSRNOT00000092854
ENSRNOT00000016167
NPC intracellular cholesterol transporter 1
chr14_-_16996962 0.05 ENSRNOT00000091936

chr5_-_173233188 0.04 ENSRNOT00000055343
transmembrane protein 88B
chr2_-_9504134 0.04 ENSRNOT00000076996
adhesion G protein-coupled receptor V1
chr8_-_58195884 0.04 ENSRNOT00000010573
acetyl-CoA acetyltransferase 1
chr10_-_61772250 0.04 ENSRNOT00000092338
ENSRNOT00000085394
ENSRNOT00000046110
serine racemase
chr1_-_282492912 0.04 ENSRNOT00000047883

chr10_-_73865364 0.03 ENSRNOT00000005226
ribosomal protein S6 kinase B1
chr2_-_206274079 0.03 ENSRNOT00000056079
homeodomain interacting protein kinase 1
chr14_+_83510278 0.03 ENSRNOT00000081161
POZ (BTB) and AT hook containing zinc finger 1
chr3_+_161413298 0.03 ENSRNOT00000023965
ENSRNOT00000088776
matrix metallopeptidase 9
chr10_+_35637133 0.03 ENSRNOT00000043085
TBC1 domain family member 9B
chr10_+_61772449 0.03 ENSRNOT00000004058
SMG6 nonsense mediated mRNA decay factor
chr6_+_72092194 0.03 ENSRNOT00000005670
G2/M-phase specific E3 ubiquitin protein ligase
chr4_+_145282797 0.03 ENSRNOT00000085766
8-oxoguanine DNA glycosylase
chr14_-_87701884 0.03 ENSRNOT00000079338
motile sperm domain containing 1
chr5_+_117586103 0.03 ENSRNOT00000084640
ubiquitin specific peptidase 1
chr11_+_73198522 0.03 ENSRNOT00000002356
xyloside xylosyltransferase 1
chr13_+_56513286 0.03 ENSRNOT00000015596
zinc finger and BTB domain containing 41
chrX_+_33599671 0.03 ENSRNOT00000006843
taxilin gamma
chr6_-_127508452 0.03 ENSRNOT00000073709
protein Z-dependent protease inhibitor-like
chr2_-_188596222 0.03 ENSRNOT00000027920
ephrin A1
chrX_-_75566481 0.03 ENSRNOT00000003714
zinc finger, DHHC-type containing 15
chr12_+_17253791 0.03 ENSRNOT00000083814
zinc finger AN1-type containing 2A
chr3_-_164728338 0.03 ENSRNOT00000035463
family with sequence similarity 65, member C
chr10_+_15183803 0.03 ENSRNOT00000039777
F-box and leucine-rich repeat protein 16
chr1_+_116604550 0.03 ENSRNOT00000083587
ubiquitin protein ligase E3A
chr1_-_89559960 0.02 ENSRNOT00000092133
sodium voltage-gated channel beta subunit 1
chrX_-_105793306 0.02 ENSRNOT00000015806
nuclear RNA export factor 2
chr18_+_28361283 0.02 ENSRNOT00000026949
matrin 3
chr9_-_19372673 0.02 ENSRNOT00000073667
ENSRNOT00000079517
chloride intracellular channel 5
chr1_+_238222521 0.02 ENSRNOT00000024000
aldehyde dehydrogenase 1 family, member A1
chr10_+_38788992 0.02 ENSRNOT00000009727
growth differentiation factor 9
chr2_+_68821004 0.02 ENSRNOT00000083713
epidermal growth factor
chr6_+_129835919 0.02 ENSRNOT00000036035
vaccinia related kinase 1
chr5_+_148320438 0.02 ENSRNOT00000018742
penta-EF hand domain containing 1
chr20_-_8574082 0.02 ENSRNOT00000048845
MAM domain containing glycosylphosphatidylinositol anchor 1
chr10_+_93811505 0.02 ENSRNOT00000081937
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr11_+_88699222 0.02 ENSRNOT00000084177
FYVE, RhoGEF and PH domain containing 4
chr3_-_133894569 0.02 ENSRNOT00000084221

chr1_+_128199322 0.02 ENSRNOT00000075131
LysM domain containing 4
chr10_-_56289882 0.02 ENSRNOT00000090762
ENSRNOT00000056903
tumor necrosis factor superfamily member 13
chr1_+_197839430 0.02 ENSRNOT00000025043
rabaptin, RAB GTPase binding effector protein 2
chr11_-_55240241 0.02 ENSRNOT00000064614
developmental pluripotency associated 4
chr1_-_141533908 0.02 ENSRNOT00000020117
mesoderm posterior bHLH transcription factor 1
chr4_+_122365093 0.02 ENSRNOT00000024011
Kruppel-like factor 15
chr4_-_170195107 0.02 ENSRNOT00000073808
uncharacterized LOC100912450
chr4_-_170813012 0.02 ENSRNOT00000073975
single-pass membrane and coiled-coil domain-containing protein 3
chrX_-_111179152 0.02 ENSRNOT00000089115
MORC family CW-type zinc finger 4
chr1_-_213635546 0.02 ENSRNOT00000018861
sirtuin 3
chr2_-_1511591 0.02 ENSRNOT00000087906
ENSRNOT00000014709
calpastatin
chr10_+_63778755 0.01 ENSRNOT00000090481
inositol polyphosphate-5-phosphatase K
chr20_+_47494270 0.01 ENSRNOT00000036365
SEC63 homolog, protein translocation regulator
chr20_+_6356423 0.01 ENSRNOT00000000628
cyclin-dependent kinase inhibitor 1A
chr19_-_37907714 0.01 ENSRNOT00000026361
chymotrypsin-like
chr18_-_69723869 0.01 ENSRNOT00000000125
elaC ribonuclease Z 1
chr13_+_49092306 0.01 ENSRNOT00000000039
NUAK family kinase 2
chr1_+_213451721 0.01 ENSRNOT00000045652
olfactory receptor 315
chr10_-_51778939 0.01 ENSRNOT00000078675
ENSRNOT00000057562
myocardin
chr3_+_149493655 0.01 ENSRNOT00000018226
BPI fold containing family A, member 2
chr10_+_11206226 0.01 ENSRNOT00000006979
transcription factor AP-4
chr10_-_47630799 0.01 ENSRNOT00000057907
solute carrier family 47 member 2
chr3_+_175493698 0.01 ENSRNOT00000087356
oxysterol binding protein-like 2
chr15_+_107486555 0.01 ENSRNOT00000074277

chr1_-_167698263 0.01 ENSRNOT00000093046
tripartite motif-containing 21
chr13_+_89774764 0.01 ENSRNOT00000005619
Rho GTPase activating protein 30
chr17_+_10066187 0.01 ENSRNOT00000091200
ubiquitin interaction motif containing 1
chr6_-_103605256 0.01 ENSRNOT00000006005
DDB1 and CUL4 associated factor 5
chr19_+_39126589 0.01 ENSRNOT00000027561
syntrophin, beta 2
chr1_-_215858034 0.01 ENSRNOT00000027656
insulin 2
chr4_-_78074906 0.01 ENSRNOT00000080654
zinc finger protein 467
chr4_+_142780987 0.01 ENSRNOT00000056570
glutamate metabotropic receptor 7
chr5_-_62001196 0.01 ENSRNOT00000012602
tRNA methyltransferase O
chr12_+_46869836 0.01 ENSRNOT00000084421
sirtuin 4
chr1_+_213636093 0.01 ENSRNOT00000019642
proteasome 26S subunit, non-ATPase 13
chr8_-_124399494 0.01 ENSRNOT00000037883
transforming growth factor, beta receptor 2
chr16_-_18645941 0.01 ENSRNOT00000079241
DPY30 domain containing 2
chr4_+_89079014 0.01 ENSRNOT00000087451
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr14_-_14390699 0.01 ENSRNOT00000046639
annexin A3
chr4_-_32087600 0.01 ENSRNOT00000013841
SEM1, 26S proteasome complex subunit
chr4_-_78075398 0.01 ENSRNOT00000010377
zinc finger protein 467
chr10_-_109966782 0.01 ENSRNOT00000078052
ENSRNOT00000075041
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_189870622 0.01 ENSRNOT00000075003
transmembrane protein 159
chr11_+_74057361 0.01 ENSRNOT00000048746
carboxypeptidase N subunit 2
chrX_+_54266687 0.01 ENSRNOT00000058309
LRRGT00076-like
chr1_+_220243473 0.01 ENSRNOT00000084650
ENSRNOT00000027091
mitochondrial ribosomal protein L11
chr7_-_99677268 0.01 ENSRNOT00000013315
similar to Hypothetical protein MGC31278
chr16_+_20962227 0.01 ENSRNOT00000027615
solute carrier family 25, member 42
chr16_+_46731403 0.01 ENSRNOT00000017624
teneurin transmembrane protein 3
chr1_-_73121085 0.01 ENSRNOT00000073464
similar to NACHT, leucine rich repeat and PYD containing 2
chr9_-_81565416 0.00 ENSRNOT00000083582
angio-associated, migratory cell protein
chr10_+_32824 0.00 ENSRNOT00000077828
meiosis arrest female protein 1-like
chr1_+_193335645 0.00 ENSRNOT00000019640
leucine carboxyl methyltransferase 1
chr12_+_40466495 0.00 ENSRNOT00000001816
aldehyde dehydrogenase 2 family (mitochondrial)
chr16_-_81834945 0.00 ENSRNOT00000037806
coagulation factor VII
chr3_+_151126591 0.00 ENSRNOT00000025859
myosin heavy chain 7B
chr3_-_176706896 0.00 ENSRNOT00000017337
protein tyrosine kinase 6
chr1_-_133559975 0.00 ENSRNOT00000046645
multiple C2 and transmembrane domain containing 2
chr4_+_118243132 0.00 ENSRNOT00000023654
similar to Hypothetical protein MGC25529
chr7_+_78732904 0.00 ENSRNOT00000088433
dendritic cell-specific transmembrane protein
chr4_-_9060554 0.00 ENSRNOT00000046248

chr9_-_63637677 0.00 ENSRNOT00000049259
SATB homeobox 2
chrX_+_159703578 0.00 ENSRNOT00000001162
CD40 ligand
chr6_-_21112734 0.00 ENSRNOT00000079819
RAS guanyl releasing protein 3
chr2_+_43271092 0.00 ENSRNOT00000017571
mesoderm induction early response 1, family member 3
chr1_-_22404002 0.00 ENSRNOT00000044098
trace amine-associated receptor 8a
chr5_-_171415354 0.00 ENSRNOT00000055398
tumor protein p73
chr1_-_240601744 0.00 ENSRNOT00000024093
aldehyde dehydrogenase family 1, subfamily A7
chr8_-_75995371 0.00 ENSRNOT00000014014
forkhead box B1
chr19_+_37600148 0.00 ENSRNOT00000023853
CCCTC-binding factor
chr3_+_122928964 0.00 ENSRNOT00000074724
rCG26795-like
chr16_-_82999827 0.00 ENSRNOT00000041223
testis expressed 29

Network of associatons between targets according to the STRING database.

First level regulatory network of T

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0046952 acetyl-CoA catabolic process(GO:0046356) ketone body catabolic process(GO:0046952) metanephric proximal tubule development(GO:0072237)
0.0 0.0 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.0 0.0 GO:0071283 response to high light intensity(GO:0009644) cellular response to iron(III) ion(GO:0071283)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)